## Mon Mar 17 21:45:36 2025
## emapper-2.1.9
## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/YYD2_bin.13.fa -m mmseqs --itype genome -o YYD2_bin.13 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/YYD2_bin.13 --cpu 8
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YYD2_k127_1021946_0	981369.JQMJ01000004_gene2915	1.545e-58	215.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,2NF31@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_1021946_1	1385515.N791_10915	5.27e-14	81.0	COG0346@1|root,COG0346@2|Bacteria,1RHM9@1224|Proteobacteria,1S6Y3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_1021946_2	1110502.TMO_1817	1.096e-12	77.0	COG2329@1|root,COG2329@2|Bacteria,1N70M@1224|Proteobacteria,2UHBM@28211|Alphaproteobacteria,2JXZQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4865)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4865
YYD2_k127_1040775_0	251221.35211292	3.197e-236	759.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
YYD2_k127_104670_1	1089550.ATTH01000001_gene1065	2.163e-100	342.0	COG0612@1|root,COG0612@2|Bacteria,4PICD@976|Bacteroidetes,1FJRH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD2_k127_104670_0	714943.Mucpa_6445	1.617e-144	483.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YYD2_k127_104670_2	237368.SCABRO_02485	5.839e-36	142.0	COG0745@1|root,COG0745@2|Bacteria	237368.SCABRO_02485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1082428_2	309807.SRU_0927	1.394e-09	70.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1FIXX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD2_k127_1082428_1	246197.MXAN_0527	3.313e-43	173.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42RBE@68525|delta/epsilon subdivisions,2WN7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD2_k127_1082428_0	1266925.JHVX01000001_gene2643	8.951e-133	436.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,372VV@32003|Nitrosomonadales	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD2_k127_1088878_0	903818.KI912268_gene1372	5.656e-08	64.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YYD2_k127_1102226_0	661478.OP10G_2194	1.918e-72	266.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
YYD2_k127_1104457_0	1125863.JAFN01000001_gene1446	1.575e-129	431.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_1104457_1	269799.Gmet_2454	2.951e-80	279.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD2_k127_1107709_1	1104324.P186_2872	7.355e-23	109.0	COG0308@1|root,arCOG02969@2157|Archaea,2XPQ3@28889|Crenarchaeota	28889|Crenarchaeota	E	PBS lyase HEAT domain protein repeat-containing protein	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,HEAT_PBS,Peptidase_M1
YYD2_k127_1107709_0	1174528.JH992898_gene938	2.584e-117	385.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1107709_2	1463920.JOGB01000018_gene5324	7.536e-15	74.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria	201174|Actinobacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
YYD2_k127_1113165_0	1121372.AULK01000005_gene1782	5.212e-07	61.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4FMGF@85023|Microbacteriaceae	201174|Actinobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YYD2_k127_1113165_1	1209989.TepiRe1_1527	9.041e-07	59.0	COG4966@1|root,COG4966@2|Bacteria,1UF09@1239|Firmicutes,25K0H@186801|Clostridia,42IS4@68295|Thermoanaerobacterales	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YYD2_k127_11181_0	243231.GSU2032	8.164e-78	273.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,43UK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YYD2_k127_11181_1	1125863.JAFN01000001_gene1507	3.872e-60	226.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YYD2_k127_11181_2	246197.MXAN_5782	9.08e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1MZCR@1224|Proteobacteria,42R7I@68525|delta/epsilon subdivisions,2WMT6@28221|Deltaproteobacteria,2YW4K@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	pilG	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_11184_7	243231.GSU2043	1.945e-31	137.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YYD2_k127_11184_10	246197.MXAN_5782	5.678e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,1MZCR@1224|Proteobacteria,42R7I@68525|delta/epsilon subdivisions,2WMT6@28221|Deltaproteobacteria,2YW4K@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	pilG	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_11184_8	1173264.KI913949_gene1190	2.075e-22	110.0	COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria,1H81Z@1150|Oscillatoriales	1117|Cyanobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
YYD2_k127_11184_5	197221.22295627	2.04e-54	205.0	COG1131@1|root,COG1131@2|Bacteria,1G0UC@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_11184_12	290397.Adeh_0635	2.909e-07	62.0	COG4969@1|root,COG4969@2|Bacteria,1Q5KV@1224|Proteobacteria,42UIT@68525|delta/epsilon subdivisions,2WQNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
YYD2_k127_11184_1	1379698.RBG1_1C00001G1210	5.226e-146	476.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_11184_6	1125863.JAFN01000001_gene2901	5.186e-38	162.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,43BPZ@68525|delta/epsilon subdivisions,2X717@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sensor histidine kinase PilS, PAS domain-containing	pilS	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4
YYD2_k127_11184_3	269799.Gmet_1395	1.559e-129	425.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43TBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YYD2_k127_11184_2	404589.Anae109_0668	2.861e-137	449.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD2_k127_11184_0	1379698.RBG1_1C00001G1743	1.745e-181	593.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YYD2_k127_11184_9	861299.J421_4159	3.096e-15	82.0	COG1555@1|root,COG1555@2|Bacteria,1ZV96@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
YYD2_k127_11184_11	330214.NIDE2640	2.269e-11	78.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE2640|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_11184_4	1122921.KB898185_gene3632	1.026e-75	263.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,26RUZ@186822|Paenibacillaceae	91061|Bacilli	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YYD2_k127_1119983_2	456320.Mvol_0239	1.42e-34	147.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y12G@28890|Euryarchaeota,23R8Z@183939|Methanococci	183939|Methanococci	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
YYD2_k127_1119983_0	479434.Sthe_1141	1.089e-82	286.0	COG0673@1|root,COG0673@2|Bacteria,2G6PI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD2_k127_1119983_1	1038867.AXAY01000016_gene1877	7.14e-39	155.0	2DDAT@1|root,2Z8YJ@2|Bacteria,1NKBV@1224|Proteobacteria,2UYD7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1119983_3	322710.Avin_30000	8.641e-32	139.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_1120079_1	927677.ALVU02000001_gene4114	3.684e-28	117.0	COG1975@1|root,COG1975@2|Bacteria,1G2SP@1117|Cyanobacteria	1117|Cyanobacteria	O	maturation factor XdhC CoxF family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
YYD2_k127_1120079_0	1123368.AUIS01000019_gene1214	2.499e-142	462.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YYD2_k127_1125946_3	411467.BACCAP_02399	2.142e-30	128.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,268PT@186813|unclassified Clostridiales	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_1125946_5	1124780.ANNU01000005_gene2436	1.024e-05	57.0	COG1366@1|root,COG1366@2|Bacteria,4NT5G@976|Bacteroidetes,47RJ2@768503|Cytophagia	976|Bacteroidetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD2_k127_1125946_4	234267.Acid_1344	8.598e-12	71.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbW	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,MatE,SpoIIE
YYD2_k127_1125946_1	240015.ACP_1487	1.03e-161	522.0	COG1027@1|root,COG1027@2|Bacteria,3Y3XS@57723|Acidobacteria,2JHYF@204432|Acidobacteriia	204432|Acidobacteriia	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
YYD2_k127_1125946_0	1191523.MROS_1690	5.499e-210	687.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria	2|Bacteria	C	malic enzyme	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
YYD2_k127_1125946_2	429009.Adeg_1730	5.576e-41	176.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42HQU@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD2_k127_1125946_6	1121405.dsmv_1320	1.197e-05	59.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD2_k127_1128840_1	1499967.BAYZ01000097_gene4350	3.227e-69	241.0	COG4826@1|root,COG4826@2|Bacteria,2NQVB@2323|unclassified Bacteria	2|Bacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YYD2_k127_1128840_0	864051.BurJ1DRAFT_0325	6.77e-146	475.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08162,ko:K08226,ko:K16211	-	-	-	-	ko00000,ko02000	2.A.1.2.21,2.A.1.41,2.A.2.6	-	-	MFS_1,PUCC
YYD2_k127_1128840_3	1356852.N008_08295	7.147e-08	65.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,47KD5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YYD2_k127_1128840_2	667014.Thein_0968	4.028e-16	84.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
YYD2_k127_1131449_2	485917.Phep_4073	2.126e-14	81.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1IW3N@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YYD2_k127_1131449_1	517418.Ctha_2484	1.217e-23	103.0	COG0713@1|root,COG0713@2|Bacteria,1FFEB@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YYD2_k127_1131449_0	1125863.JAFN01000001_gene2410	1.053e-168	543.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YYD2_k127_1146511_3	1379698.RBG1_1C00001G0055	2.9e-32	141.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YYD2_k127_1146511_1	194439.CT1949	9.814e-56	209.0	COG0451@1|root,COG0451@2|Bacteria,1FDUB@1090|Chlorobi	1090|Chlorobi	M	3-beta hydroxysteroid dehydrogenase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD2_k127_1146511_0	1144275.COCOR_04256	1.393e-114	380.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1146511_4	1121380.JNIW01000089_gene2929	8.071e-25	110.0	2FGUY@1|root,348Q9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1146511_5	234267.Acid_3395	3.474e-24	114.0	2FGUY@1|root,348Q9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1146511_6	744872.Spica_1365	2.828e-20	107.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2J5MW@203691|Spirochaetes	203691|Spirochaetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
YYD2_k127_1146511_2	187272.Mlg_2251	2.417e-44	169.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1WWPE@135613|Chromatiales	135613|Chromatiales	G	HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD2_k127_1222952_0	234267.Acid_2121	6.078e-51	196.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_2121|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
YYD2_k127_1222952_1	379066.GAU_3840	7.66e-47	176.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD2_k127_122754_1	1131269.AQVV01000038_gene1561	1.843e-47	177.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	bacE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
YYD2_k127_122754_0	945713.IALB_1163	7.557e-68	250.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
YYD2_k127_1227593_0	1121920.AUAU01000019_gene2603	2.983e-94	328.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12065	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Porin_O_P
YYD2_k127_1227593_1	1125863.JAFN01000001_gene3582	7.317e-07	62.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
YYD2_k127_1254141_3	395961.Cyan7425_1597	7.621e-17	83.0	COG0735@1|root,COG0735@2|Bacteria,1G5UC@1117|Cyanobacteria,3KI9M@43988|Cyanothece	1117|Cyanobacteria	K	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YYD2_k127_1254141_1	1121920.AUAU01000007_gene500	1.252e-68	235.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria	57723|Acidobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YYD2_k127_1254141_0	608538.HTH_1527	1.027e-116	390.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,DUF3501,Fer4_8
YYD2_k127_1254141_2	502025.Hoch_2200	2.71e-36	144.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
YYD2_k127_1254141_4	290315.Clim_0596	4.356e-15	79.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
YYD2_k127_1254141_5	880073.Calab_2401	2.758e-10	63.0	COG2374@1|root,COG2374@2|Bacteria,2NRB5@2323|unclassified Bacteria	2|Bacteria	G	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,LTD
YYD2_k127_1259512_0	637905.SVI_1691	1.104e-116	391.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
YYD2_k127_1259512_1	1380390.JIAT01000009_gene1779	2.649e-41	166.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
YYD2_k127_127440_0	1121935.AQXX01000098_gene1654	7.332e-16	81.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1XKMI@135619|Oceanospirillales	135619|Oceanospirillales	CO	Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
YYD2_k127_127440_1	635013.TherJR_1839	3.771e-11	75.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,2629I@186807|Peptococcaceae	186801|Clostridia	T	PFAM Prokaryotic dksA traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
YYD2_k127_127497_7	1444309.JAQG01000087_gene2644	4.98e-09	65.0	COG0745@1|root,COG0745@2|Bacteria,1UECI@1239|Firmicutes,4HENE@91061|Bacilli,26SXE@186822|Paenibacillaceae	91061|Bacilli	T	regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_127497_5	314345.SPV1_10361	6.294e-12	72.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria	1224|Proteobacteria	U	Preprotein translocase, subunit SecG	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YYD2_k127_127497_1	1121468.AUBR01000012_gene2583	1.633e-76	266.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,42FAI@68295|Thermoanaerobacterales	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YYD2_k127_127497_6	1341151.ASZU01000008_gene1623	4.031e-11	75.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,27BKM@186824|Thermoactinomycetaceae	91061|Bacilli	G	Phosphoglycerate kinase	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
YYD2_k127_127497_0	517417.Cpar_2077	7.008e-125	411.0	COG0126@1|root,COG0126@2|Bacteria,1FDBD@1090|Chlorobi	1090|Chlorobi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YYD2_k127_127497_4	880073.Calab_0143	1.088e-13	84.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
YYD2_k127_127497_2	945713.IALB_1643	2.869e-54	207.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_127497_3	459349.CLOAM0604	2.47e-16	85.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1286531_3	1089550.ATTH01000001_gene554	8.495e-05	50.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_1286531_2	945713.IALB_2417	7.971e-09	69.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	ASH,C_GCAxxG_C_C,FlgD_ig,Peptidase_S74
YYD2_k127_1286531_1	1379698.RBG1_1C00001G0069	3.554e-89	320.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CHU_C,FlgD_ig,PKD,Peptidase_S8
YYD2_k127_1286531_0	1232410.KI421415_gene3010	3.139e-97	330.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43S8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YYD2_k127_1324632_4	1293048.CBMB010000003_gene1284	2.344e-06	59.0	arCOG08110@1|root,arCOG08110@2157|Archaea,2XUWV@28890|Euryarchaeota,23S8I@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1324632_1	1121428.DESHY_80106___1	8.004e-26	118.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,261ZV@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YYD2_k127_1324632_2	1122222.AXWR01000009_gene680	1.557e-20	108.0	COG1597@1|root,COG1597@2|Bacteria,1WI0N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Diacylglycerol kinase, catalytic	bmrU	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YYD2_k127_1324632_3	215803.DB30_3774	5.86e-12	79.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YVF7@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,Aminotran_1_2
YYD2_k127_1324632_0	883.DvMF_0664	1.212e-37	147.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2M9PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD2_k127_132747_1	690850.Desaf_1376	5.853e-09	66.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Big_5,LVIVD,Laminin_G_3,PKD
YYD2_k127_132747_0	682795.AciX8_0967	1.307e-27	126.0	COG3503@1|root,COG3503@2|Bacteria,3Y6EK@57723|Acidobacteria,2JKNW@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
YYD2_k127_132747_2	1177181.T9A_02292	0.0009263	53.0	COG1657@1|root,COG2304@1|root,COG1657@2|Bacteria,COG2304@2|Bacteria,1RFDH@1224|Proteobacteria,1S0SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF1194,Prenyltrans
YYD2_k127_1348623_3	1316927.ATKI01000120_gene3667	6.751e-24	116.0	COG2244@1|root,COG2244@2|Bacteria,1QS7T@1224|Proteobacteria,1RU3F@1236|Gammaproteobacteria,1YNMJ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
YYD2_k127_1348623_0	880073.Calab_0265	1.511e-65	256.0	COG0760@1|root,COG0760@2|Bacteria,2NP7B@2323|unclassified Bacteria	2|Bacteria	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
YYD2_k127_1348623_2	574087.Acear_0620	1.65e-54	217.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YYD2_k127_1348623_1	748449.Halha_1884	2.822e-58	230.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YYD2_k127_1353984_1	1125863.JAFN01000001_gene3034	1.245e-51	207.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
YYD2_k127_1353984_0	1499967.BAYZ01000193_gene3921	8.521e-67	246.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
YYD2_k127_1353984_2	682795.AciX8_4862	3.997e-45	168.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria,2JJ1A@204432|Acidobacteriia	204432|Acidobacteriia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YYD2_k127_1355571_0	1279009.ADICEAN_00215	1.05e-82	280.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes	976|Bacteroidetes	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_1355571_1	861299.J421_1535	1.297e-67	235.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_1355571_2	1121920.AUAU01000006_gene258	3.781e-61	224.0	COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria	57723|Acidobacteria	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
YYD2_k127_1356823_1	521011.Mpal_2209	5.048e-36	152.0	COG0614@1|root,COG3291@1|root,arCOG02510@2157|Archaea,arCOG03611@2157|Archaea	2157|Archaea	P	PFAM PKD domain containing protein	ush	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	CBM_6,DUF839,NHL,NosD,PKD,Peptidase_C1,Peptidase_S8
YYD2_k127_1356823_2	1151117.AJLF01000001_gene704	7.492e-07	63.0	COG5617@1|root,arCOG07110@2157|Archaea,2Y38Y@28890|Euryarchaeota,24337@183968|Thermococci	183968|Thermococci	S	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
YYD2_k127_1356823_0	290397.Adeh_0591	1.638e-73	262.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2Z30T@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YYD2_k127_1361213_1	342610.Patl_1912	2.309e-83	289.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	ERAP1-like C-terminal domain	-	-	3.4.11.14,3.4.11.2	ko:K01256,ko:K01263	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
YYD2_k127_1361213_6	518766.Rmar_0721	1.661e-11	78.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1361213_0	1379698.RBG1_1C00001G0069	2.478e-93	340.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NRP6@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CHU_C,FlgD_ig,PKD,Peptidase_S8
YYD2_k127_1361213_7	871963.Desdi_1116	3.855e-09	66.0	COG3088@1|root,COG3088@2|Bacteria,1VNV1@1239|Firmicutes,254YU@186801|Clostridia	186801|Clostridia	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
YYD2_k127_1361213_2	1379698.RBG1_1C00001G0205	1.345e-81	297.0	COG0648@1|root,COG0648@2|Bacteria,2NNN3@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
YYD2_k127_1361213_4	1117958.PE143B_0114680	1.204e-34	140.0	COG0847@1|root,COG0847@2|Bacteria,1RDF2@1224|Proteobacteria	1224|Proteobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF5051,RNase_T
YYD2_k127_1361213_5	1125863.JAFN01000001_gene3046	6.389e-31	128.0	2CEMF@1|root,33GFG@2|Bacteria,1NIQ6@1224|Proteobacteria,42X94@68525|delta/epsilon subdivisions,2WSWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1361213_3	671143.DAMO_2127	4.576e-39	154.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD2_k127_1362991_0	595460.RRSWK_05402	2.404e-179	578.0	COG0243@1|root,COG0243@2|Bacteria,2IXVV@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
YYD2_k127_1365301_3	204669.Acid345_4034	3.058e-19	90.0	COG0498@1|root,COG0498@2|Bacteria,3Y2GX@57723|Acidobacteria,2JHWS@204432|Acidobacteriia	204432|Acidobacteriia	E	TIGRFAM Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_1365301_2	314230.DSM3645_15830	7.329e-25	116.0	COG1158@1|root,COG1158@2|Bacteria,2J3DE@203682|Planctomycetes	203682|Planctomycetes	K	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
YYD2_k127_1365301_1	1122611.KB903940_gene1994	4.615e-49	180.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4EJX7@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
YYD2_k127_1365301_0	1242864.D187_004349	5.05e-54	194.0	COG5500@1|root,COG5500@2|Bacteria,1N0PP@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
YYD2_k127_1368160_1	1038859.AXAU01000016_gene6869	2.357e-57	202.0	COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
YYD2_k127_1368160_0	215803.DB30_7610	9.311e-75	283.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YYD2_k127_137102_0	234831.PSM_A0515	1.174e-86	306.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	ERAP1-like C-terminal domain	-	-	3.4.11.14,3.4.11.2	ko:K01256,ko:K01263	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
YYD2_k127_137102_1	1121377.KB906400_gene1258	1.783e-33	141.0	COG1794@1|root,COG1794@2|Bacteria	2|Bacteria	M	racemase activity, acting on amino acids and derivatives	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
YYD2_k127_137800_0	292459.STH3193	8.686e-105	351.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
YYD2_k127_137800_1	1382304.JNIL01000001_gene450	9.619e-96	344.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
YYD2_k127_137800_4	1089547.KB913013_gene2762	2.825e-07	59.0	COG2456@1|root,COG2456@2|Bacteria,4NSNR@976|Bacteroidetes,47RRP@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
YYD2_k127_137800_3	290397.Adeh_3051	3.874e-62	224.0	COG1216@1|root,COG1216@2|Bacteria,1QW1K@1224|Proteobacteria,43BRI@68525|delta/epsilon subdivisions,2WN0V@28221|Deltaproteobacteria,2Z30Y@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_137800_2	713586.KB900536_gene594	4.273e-73	253.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1WX4B@135613|Chromatiales	135613|Chromatiales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YYD2_k127_1385236_0	572477.Alvin_2609	6.459e-67	243.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RZRG@1236|Gammaproteobacteria,1WVXI@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_1385236_4	272134.KB731324_gene6634	1.367e-34	136.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1HBSI@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_1385236_5	357808.RoseRS_2793	7.359e-27	122.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi,375U9@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_1385236_1	1123366.TH3_20738	1.407e-50	186.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2JS6U@204441|Rhodospirillales	204441|Rhodospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
YYD2_k127_1385236_3	1207063.P24_08169	1.052e-36	151.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2U9G3@28211|Alphaproteobacteria,2JTMJ@204441|Rhodospirillales	204441|Rhodospirillales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
YYD2_k127_1385236_6	1333507.AUTQ01000059_gene3622	2.094e-20	97.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,2Q2HJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	TQO small subunit DoxD	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YYD2_k127_1385236_7	1379281.AVAG01000110_gene232	1.182e-10	73.0	COG2881@1|root,COG2881@2|Bacteria,1N6EP@1224|Proteobacteria,42U9Y@68525|delta/epsilon subdivisions,2WQGR@28221|Deltaproteobacteria,2MAET@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Yip1,zinc_ribbon_4
YYD2_k127_1385236_2	665571.STHERM_c18030	1.474e-37	152.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD2_k127_1385236_8	1210884.HG799462_gene8426	4.257e-07	52.0	COG1186@1|root,COG1186@2|Bacteria,2IZSY@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
YYD2_k127_1391147_1	759362.KVU_0741	0.0002536	51.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD2_k127_1391147_0	448385.sce4660	1.061e-68	241.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2Z3JZ@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
YYD2_k127_1408303_1	1125863.JAFN01000001_gene1391	1.303e-75	285.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
YYD2_k127_1408303_0	105559.Nwat_1650	2.334e-133	447.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1SYTD@1236|Gammaproteobacteria,1X2IM@135613|Chromatiales	135613|Chromatiales	EO	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M1,Peptidase_M28
YYD2_k127_1414985_1	1121289.JHVL01000009_gene1414	8.128e-17	86.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia,36JMK@31979|Clostridiaceae	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
YYD2_k127_1414985_0	1267534.KB906754_gene3274	4.742e-52	209.0	COG0265@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
YYD2_k127_1423373_1	103690.17134335	0.0003978	48.0	COG4671@1|root,COG4671@2|Bacteria,1G0X1@1117|Cyanobacteria,1HNIA@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iJN678.sll1722	Glyco_tran_28_C
YYD2_k127_1423373_0	771875.Ferpe_0714	2.382e-75	275.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
YYD2_k127_1432785_1	743722.Sph21_1159	7.313e-69	241.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YYD2_k127_1432785_0	481448.Minf_2176	2.133e-253	790.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,37G43@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD2_k127_1432785_2	290397.Adeh_3593	1.862e-36	140.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YYD2_k127_1438329_0	1191523.MROS_2418	3.382e-294	916.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YYD2_k127_144250_2	760568.Desku_1273	1.484e-119	404.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2611D@186807|Peptococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
YYD2_k127_144250_0	1380763.BG53_03300	1.441e-181	585.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,26TDB@186822|Paenibacillaceae	91061|Bacilli	I	catalyzes the conversion of acetate and CoA to acetyl-CoA	acsA_1	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
YYD2_k127_144250_4	493475.GARC_5136	0.0001872	49.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP-7	-	-	-	-	-	-	-	-	-	-	-	PP-binding
YYD2_k127_144250_1	1313301.AUGC01000008_gene386	3.207e-159	517.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_144250_3	1121918.ARWE01000001_gene50	6.187e-06	53.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1Q5XI@1224|Proteobacteria,437EC@68525|delta/epsilon subdivisions,2X2KQ@28221|Deltaproteobacteria,43VY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1453865_1	107636.JQNK01000004_gene852	0.0003327	53.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,36ZR3@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
YYD2_k127_1453865_0	945713.IALB_2930	2.508e-52	196.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1459548_0	1267535.KB906767_gene447	2.535e-60	227.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
YYD2_k127_1459548_1	886293.Sinac_4051	7.516e-20	100.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD2_k127_1469291_1	56780.SYN_02178	7.345e-57	202.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2MQDY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD2_k127_1469291_0	635013.TherJR_2972	7.835e-144	474.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YYD2_k127_1469291_2	1380390.JIAT01000011_gene2863	7.591e-18	98.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CP8Q@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
YYD2_k127_15019_0	1379698.RBG1_1C00001G1786	1.688e-18	95.0	2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_15019_1	1379698.RBG1_1C00001G1785	1.618e-13	81.0	2EAWV@1|root,334Y2@2|Bacteria,2NRSF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_15019_2	589865.DaAHT2_2116	2.562e-05	55.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
YYD2_k127_150222_0	1125863.JAFN01000001_gene1060	2.066e-76	272.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_150222_1	867903.ThesuDRAFT_00680	2.032e-29	126.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3WCM6@538999|Clostridiales incertae sedis	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YYD2_k127_150222_2	1121405.dsmv_3383	1.485e-12	72.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
YYD2_k127_1512796_2	521674.Plim_0157	2.835e-27	122.0	COG1011@1|root,COG1011@2|Bacteria,2J40T@203682|Planctomycetes	203682|Planctomycetes	S	subfamily IA, variant 1	-	-	3.1.3.5	ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD2_k127_1512796_1	1125863.JAFN01000001_gene2408	5.244e-107	383.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YYD2_k127_1512796_0	1379698.RBG1_1C00001G1061	3.208e-179	576.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YYD2_k127_1529980_0	1379698.RBG1_1C00001G1461	2.444e-101	335.0	COG1788@1|root,COG1788@2|Bacteria,2NPDX@2323|unclassified Bacteria	2|Bacteria	I	Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01034	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
YYD2_k127_1529980_1	1123389.ATXJ01000007_gene1692	5.486e-15	76.0	COG2185@1|root,COG2185@2|Bacteria,1WJS8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM methylmalonyl-CoA mutase C-terminal domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
YYD2_k127_1534157_0	240015.ACP_0992	6.776e-08	66.0	COG0457@1|root,COG0457@2|Bacteria	240015.ACP_0992|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1555989_0	1379698.RBG1_1C00001G0119	1.024e-90	312.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_159735_2	671143.DAMO_1275	3.902e-37	145.0	COG0471@1|root,COG0471@2|Bacteria,2NPNA@2323|unclassified Bacteria	2|Bacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319,ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47,2.A.47.1	-	-	Na_sulph_symp
YYD2_k127_159735_3	326427.Cagg_1049	2.308e-28	119.0	COG0838@1|root,COG0838@2|Bacteria,2G78Y@200795|Chloroflexi,375UC@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YYD2_k127_159735_1	1121403.AUCV01000026_gene2341	7.422e-68	243.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2MNCS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD2_k127_159735_0	1150621.SMUL_0519	3.042e-180	585.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
YYD2_k127_1633228_2	768710.DesyoDRAFT_4997	1.318e-66	235.0	COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,247QD@186801|Clostridia,26493@186807|Peptococcaceae	186801|Clostridia	H	PFAM Citrate lyase, alpha subunit (CitF)	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19975	CitF
YYD2_k127_1633228_0	404380.Gbem_3859	7.582e-124	409.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,42NDX@68525|delta/epsilon subdivisions,2X5NC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.25,4.1.3.34	ko:K01644,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YYD2_k127_1633228_3	1304888.ATWF01000002_gene212	9.919e-48	178.0	COG1661@1|root,COG1661@2|Bacteria,2GGFV@200930|Deferribacteres	200930|Deferribacteres	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
YYD2_k127_1633228_4	443143.GM18_4292	8.984e-21	96.0	COG3052@1|root,COG3052@2|Bacteria,1N20F@1224|Proteobacteria,433DT@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Covalent carrier of the coenzyme of citrate lyase	citD	-	-	ko:K01646	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001	-	-	-	ACP
YYD2_k127_1633228_1	404380.Gbem_3862	2.214e-99	335.0	COG3053@1|root,COG3053@2|Bacteria,1NGEJ@1224|Proteobacteria	1224|Proteobacteria	H	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase	citC	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008771,GO:0009987,GO:0016874,GO:0016877,GO:0016878,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	6.2.1.22	ko:K01910	ko02020,map02020	-	R04449	RC00012,RC00039	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Citrate_ly_lig
YYD2_k127_1637172_2	344747.PM8797T_00025	4.799e-30	124.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YYD2_k127_1637172_0	1047013.AQSP01000142_gene195	1.551e-102	349.0	COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YYD2_k127_1637172_4	1280689.AUJC01000009_gene3414	2.76e-29	130.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,36E2T@31979|Clostridiaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YYD2_k127_1637172_1	1385515.N791_03730	3.301e-50	190.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1X51A@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_1637172_3	1121406.JAEX01000001_gene384	2.729e-29	131.0	COG0438@1|root,COG0438@2|Bacteria,1PDTW@1224|Proteobacteria,42P4N@68525|delta/epsilon subdivisions,2WKT5@28221|Deltaproteobacteria,2M9ET@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
YYD2_k127_1637256_0	1121920.AUAU01000008_gene1589	0.0	1751.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,3Y415@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
YYD2_k127_1637256_1	1121920.AUAU01000008_gene1590	7.889e-121	398.0	COG0167@1|root,COG0167@2|Bacteria,3Y464@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YYD2_k127_1637256_2	1499967.BAYZ01000159_gene545	4.232e-26	124.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_4_9,Exo_endo_phos,F5_F8_type_C,FIVAR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N
YYD2_k127_1639452_3	1172188.KB911820_gene2242	1.322e-52	211.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4FEV0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M36
YYD2_k127_1639452_11	1382359.JIAL01000001_gene29	1.866e-12	68.0	COG2128@1|root,COG2128@2|Bacteria,3Y8IA@57723|Acidobacteria,2JNES@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YYD2_k127_1639452_8	204669.Acid345_1839	2.685e-18	87.0	COG2128@1|root,COG2128@2|Bacteria,3Y8IA@57723|Acidobacteria,2JNES@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YYD2_k127_1639452_0	247490.KSU1_B0016	3.159e-122	416.0	COG0158@1|root,COG0158@2|Bacteria,2IWT3@203682|Planctomycetes	203682|Planctomycetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
YYD2_k127_1639452_7	768710.DesyoDRAFT_4571	5.06e-19	98.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,262G3@186807|Peptococcaceae	186801|Clostridia	D	PFAM DivIVA	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
YYD2_k127_1639452_1	314230.DSM3645_15720	4.311e-93	314.0	COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
YYD2_k127_1639452_4	1379698.RBG1_1C00001G0104	6.051e-30	123.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YYD2_k127_1639452_5	1121406.JAEX01000019_gene2782	9.617e-27	115.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,2MB6W@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YYD2_k127_1639452_2	335543.Sfum_3657	1.046e-78	273.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD2_k127_1639452_6	880073.Calab_1909	1.083e-19	101.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YYD2_k127_1639452_9	204669.Acid345_2515	7.335e-18	91.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria,2JJGJ@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
YYD2_k127_1639452_10	1120971.AUCA01000020_gene1013	1.015e-13	81.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,278JB@186823|Alicyclobacillaceae	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YYD2_k127_1639452_12	1118054.CAGW01000018_gene4265	3.596e-08	63.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,26Q9M@186822|Paenibacillaceae	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
YYD2_k127_1640905_1	1291050.JAGE01000001_gene62	5.096e-31	138.0	COG0477@1|root,COG2814@2|Bacteria,1V19N@1239|Firmicutes	1239|Firmicutes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_1640905_0	1120985.AUMI01000011_gene577	5.087e-36	145.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H355@909932|Negativicutes	909932|Negativicutes	P	Transporter DASS family	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YYD2_k127_1649166_2	1121430.JMLG01000001_gene2276	9.048e-42	162.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25ZY0@186807|Peptococcaceae	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YYD2_k127_1649166_1	452637.Oter_0497	1.251e-89	306.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD2_k127_1649166_0	1278073.MYSTI_03397	0.0	1219.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YYD2_k127_1649166_3	530564.Psta_4139	1.3e-12	70.0	COG2096@1|root,COG2096@2|Bacteria,2IZZ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YYD2_k127_1668933_1	1499967.BAYZ01000157_gene602	1.223e-74	266.0	COG1686@1|root,COG1686@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YYD2_k127_1668933_2	1499967.BAYZ01000157_gene602	1.811e-60	229.0	COG1686@1|root,COG1686@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
YYD2_k127_1668933_0	56780.SYN_00357	2.537e-145	477.0	COG1351@1|root,COG1351@2|Bacteria,1QF4I@1224|Proteobacteria,43A0P@68525|delta/epsilon subdivisions,2X9Q1@28221|Deltaproteobacteria,2MSCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
YYD2_k127_1668933_3	1163407.UU7_00150	4.477e-08	57.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria,1SCXB@1236|Gammaproteobacteria,1X823@135614|Xanthomonadales	135614|Xanthomonadales	O	Methyltransferase	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	PEMT
YYD2_k127_1672895_4	518766.Rmar_2387	3.861e-08	65.0	COG3203@1|root,COG3203@2|Bacteria,4NPPT@976|Bacteroidetes	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1672895_1	671143.DAMO_1620	1.199e-138	449.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YYD2_k127_1672895_0	671143.DAMO_1619	1.519e-249	786.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YYD2_k127_1672895_2	941639.BCO26_0942	6.407e-68	240.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,1ZCSW@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD2_k127_1672895_3	443218.AS9A_2937	1.42e-47	186.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,235FM@1762|Mycobacteriaceae	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
YYD2_k127_1672895_5	1224164.B843_00285	3.671e-05	55.0	COG2227@1|root,COG2227@2|Bacteria,2H5TR@201174|Actinobacteria,22NJK@1653|Corynebacteriaceae	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YYD2_k127_1672941_3	398720.MED217_09657	3.896e-05	54.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia,2XIM3@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD2_k127_1672941_2	1449063.JMLS01000001_gene4225	7.79e-08	62.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria,1UV23@1239|Firmicutes,4HTNN@91061|Bacilli	91061|Bacilli	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
YYD2_k127_1672941_1	861299.J421_1145	1.421e-35	144.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YYD2_k127_1672941_0	269799.Gmet_0988	2.012e-41	157.0	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2WP3N@28221|Deltaproteobacteria,43UZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
YYD2_k127_1672941_4	247490.KSU1_C0449	0.0001623	54.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
YYD2_k127_1674145_3	449673.BACSTE_01319	2.066e-24	116.0	COG0438@1|root,COG0438@2|Bacteria,4NM38@976|Bacteroidetes,2FNUT@200643|Bacteroidia,4ANIE@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_1674145_1	56110.Oscil6304_1713	3.69e-44	176.0	COG5653@1|root,COG5653@2|Bacteria,1GC7U@1117|Cyanobacteria,1HEMP@1150|Oscillatoriales	1117|Cyanobacteria	M	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YYD2_k127_1674145_0	338963.Pcar_1124	9.65e-63	229.0	COG0535@1|root,COG0535@2|Bacteria,1QUN1@1224|Proteobacteria,42WPW@68525|delta/epsilon subdivisions,2WVZ2@28221|Deltaproteobacteria,43VU9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
YYD2_k127_1674145_2	1307761.L21SP2_2314	3.124e-33	134.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD2_k127_1674257_0	1232410.KI421426_gene1341	2.929e-199	651.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
YYD2_k127_1674257_1	1121920.AUAU01000016_gene1287	1.306e-47	194.0	COG1633@1|root,COG1633@2|Bacteria,3Y925@57723|Acidobacteria	57723|Acidobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YYD2_k127_1682311_0	452637.Oter_2033	1.232e-86	305.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
YYD2_k127_1682311_2	306281.AJLK01000162_gene58	2.033e-13	72.0	COG2002@1|root,COG2002@2|Bacteria,1G9J8@1117|Cyanobacteria,1JJ0Y@1189|Stigonemataceae	1117|Cyanobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PrlF_antitoxin
YYD2_k127_1682311_1	331678.Cphamn1_1153	2.608e-14	79.0	COG5611@1|root,COG5611@2|Bacteria,1FFDE@1090|Chlorobi	1090|Chlorobi	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD2_k127_1689100_1	351348.Maqu_1656	7.883e-84	287.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
YYD2_k127_1689100_3	1452718.JBOY01000161_gene2110	3.007e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YYD2_k127_1689100_2	269799.Gmet_1993	7.048e-62	239.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,42PTN@68525|delta/epsilon subdivisions,2WKBJ@28221|Deltaproteobacteria,43SC3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c
YYD2_k127_1689100_0	243231.GSU1940	1.967e-124	413.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria,43TK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_1695399_0	1122179.KB890436_gene1409	6.01e-28	131.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YYD2_k127_1698160_1	204669.Acid345_4646	1.11e-31	140.0	COG0303@1|root,COG0303@2|Bacteria,3Y3F0@57723|Acidobacteria,2JICE@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YYD2_k127_1698160_0	1458427.BAWN01000032_gene1823	1.266e-49	186.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ6F@28216|Betaproteobacteria,4ADGN@80864|Comamonadaceae	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YYD2_k127_170679_0	240015.ACP_2544	8.341e-140	462.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD2_k127_1719862_0	1121403.AUCV01000013_gene4008	1.571e-109	369.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions,2X7M8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1719862_1	103733.JNYO01000050_gene1301	1.865e-05	53.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXC3@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
YYD2_k127_172336_5	880073.Calab_2548	0.0006972	44.0	COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,LVIVD,TSP_3
YYD2_k127_172336_3	518766.Rmar_2487	3.064e-52	198.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1FJ65@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YYD2_k127_172336_1	562970.Btus_1567	2.932e-80	289.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,277XZ@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YYD2_k127_172336_4	1380763.BG53_03370	9.413e-34	149.0	COG2227@1|root,COG2227@2|Bacteria,1V1FG@1239|Firmicutes,4HFP0@91061|Bacilli,26UIQ@186822|Paenibacillaceae	91061|Bacilli	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
YYD2_k127_172336_0	309801.trd_1791	9.162e-96	344.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
YYD2_k127_172336_2	1379698.RBG1_1C00001G0380	5.294e-62	230.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YYD2_k127_1750582_1	1267533.KB906733_gene3472	1.458e-90	310.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
YYD2_k127_1750582_3	1121875.KB907548_gene1637	3.841e-20	106.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
YYD2_k127_1750582_0	1168034.FH5T_19015	1.049e-113	390.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1750582_2	498848.TaqDRAFT_3772	3.092e-22	105.0	COG0737@1|root,COG0737@2|Bacteria,1WI46@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
YYD2_k127_1755347_0	264462.Bd2562	1.118e-29	135.0	COG5276@1|root,COG5276@2|Bacteria,1RBM1@1224|Proteobacteria,42TF9@68525|delta/epsilon subdivisions,2MU9U@213481|Bdellovibrionales,2WPX5@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YYD2_k127_1772755_1	448385.sce9040	9.083e-23	114.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2YU4W@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YYD2_k127_1772755_0	518766.Rmar_1656	6.802e-315	989.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	2.7.2.4,4.1.1.20	ko:K00928,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD2_k127_1772755_2	404589.Anae109_3022	2.935e-17	88.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
YYD2_k127_1772755_3	404589.Anae109_1632	3.041e-06	56.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
YYD2_k127_1813259_0	880073.Calab_0065	1.456e-66	247.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YYD2_k127_1813259_1	1379698.RBG1_1C00001G1136	2.551e-07	59.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	ciaB	-	-	ko:K07502,ko:K08309,ko:K19804,ko:K21572	-	-	-	-	ko00000,ko01000,ko01011,ko02000	8.A.46.1,8.A.46.3	GH23	-	SusD-like_3,SusD_RagB,TPR_16,TPR_6,TPR_8
YYD2_k127_184308_4	1123376.AUIU01000017_gene102	3.491e-26	108.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	modE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
YYD2_k127_184308_0	404589.Anae109_0505	1.127e-126	412.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YYD2_k127_184308_2	156889.Mmc1_3202	1.14e-49	184.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YYD2_k127_184308_1	945713.IALB_2784	6.747e-90	329.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
YYD2_k127_184308_3	706587.Desti_2735	2.48e-28	119.0	COG1729@1|root,COG4232@1|root,COG1729@2|Bacteria,COG4232@2|Bacteria,1N0AW@1224|Proteobacteria,42TGH@68525|delta/epsilon subdivisions,2WQ33@28221|Deltaproteobacteria,2MRZ1@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,Thioredoxin_2,Thioredoxin_7
YYD2_k127_184308_5	290397.Adeh_1416	1.382e-12	78.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH,HNH_4
YYD2_k127_1864164_1	309807.SRU_1237	3.798e-51	187.0	COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,1FIQS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
YYD2_k127_1864164_0	203124.Tery_0447	1.071e-89	306.0	COG1611@1|root,COG1611@2|Bacteria,1G0JD@1117|Cyanobacteria,1H6ZX@1150|Oscillatoriales	1117|Cyanobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD2_k127_1884092_1	1047013.AQSP01000052_gene2600	1.754e-100	337.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD2_k127_1884092_2	1047013.AQSP01000052_gene2599	6.306e-93	322.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD2_k127_1884092_4	1121405.dsmv_0796	1.875e-48	197.0	COG0287@1|root,COG0287@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
YYD2_k127_1884092_0	1379698.RBG1_1C00001G0698	2.741e-298	936.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
YYD2_k127_1884092_3	481448.Minf_1377	7.056e-91	315.0	COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,37GEM@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
YYD2_k127_1884092_5	886293.Sinac_2273	2.437e-33	141.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
YYD2_k127_1884092_6	243230.DR_0234	1.689e-19	97.0	COG3860@1|root,COG3860@2|Bacteria,1WN7K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087
YYD2_k127_1884092_7	1132441.KI519455_gene2739	2.58e-05	54.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
YYD2_k127_1885582_1	1125863.JAFN01000001_gene3450	8.126e-151	497.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
YYD2_k127_1885582_2	401526.TcarDRAFT_2301	7.918e-84	289.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,4H2FP@909932|Negativicutes	909932|Negativicutes	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YYD2_k127_1885582_0	1038859.AXAU01000016_gene6869	5.243e-198	626.0	COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
YYD2_k127_1885582_3	518766.Rmar_2393	4.611e-05	49.0	COG2730@1|root,COG2911@1|root,COG2730@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,CBM60,CBM_2,CBM_3,CBM_35,CBM_6,CHB_HEX_C_1,Cellulase,F5_F8_type_C,FlgD_ig,Glyco_hydro_44,Pec_lyase_C,fn3
YYD2_k127_190076_1	266779.Meso_2458	2.894e-32	130.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
YYD2_k127_190076_0	404589.Anae109_3668	2.136e-188	597.0	COG2197@1|root,COG2197@2|Bacteria,1R03J@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
YYD2_k127_1910695_2	880073.Calab_0993	1.275e-16	87.0	COG4194@1|root,COG4194@2|Bacteria	2|Bacteria	K	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
YYD2_k127_1910695_5	1313172.YM304_41870	6.021e-05	50.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
YYD2_k127_1910695_3	591159.ACEZ01000104_gene5138	7.764e-07	61.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YYD2_k127_1910695_0	1047013.AQSP01000139_gene2416	4.963e-92	335.0	COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_1910695_4	59374.Fisuc_1197	9.694e-06	57.0	2C26A@1|root,33DD0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1910695_1	1089550.ATTH01000001_gene2205	7.939e-18	96.0	COG4775@1|root,COG4775@2|Bacteria,4P624@976|Bacteroidetes,1FIN0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD2_k127_1913261_2	861299.J421_3473	3.478e-21	103.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YYD2_k127_1913261_0	880073.Calab_2803	1.258e-215	677.0	COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
YYD2_k127_1931070_2	204669.Acid345_3322	1.852e-17	89.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_1931070_0	880073.Calab_2355	6.81e-226	709.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
YYD2_k127_1931070_1	296591.Bpro_1660	1.835e-18	92.0	COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,2WBYH@28216|Betaproteobacteria,4AIJ8@80864|Comamonadaceae	28216|Betaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD2_k127_1931602_3	1051632.TPY_0375	1.774e-19	90.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,24JQE@186801|Clostridia,3WDJF@538999|Clostridiales incertae sedis	186801|Clostridia	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YYD2_k127_1931602_1	880072.Desac_0143	1.355e-45	177.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
YYD2_k127_1931602_2	869210.Marky_1393	1.094e-43	173.0	COG1108@1|root,COG1108@2|Bacteria,1WJ32@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type Mn2 Zn2 transport systems permease components	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
YYD2_k127_1931602_0	1379698.RBG1_1C00001G1377	6.388e-72	254.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
YYD2_k127_1936180_3	1123389.ATXJ01000006_gene2264	1.759e-18	87.0	COG0111@1|root,COG0111@2|Bacteria,1WJ6E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
YYD2_k127_1936180_4	1123023.JIAI01000008_gene1487	3.481e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DXVD@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
YYD2_k127_1936180_2	1408433.JHXV01000005_gene2349	1.529e-37	159.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
YYD2_k127_1936180_0	1267533.KB906733_gene3472	5.616e-134	459.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
YYD2_k127_1936180_1	1173026.Glo7428_1851	1.311e-88	304.0	COG1653@1|root,COG1653@2|Bacteria,1G0AA@1117|Cyanobacteria	1117|Cyanobacteria	G	ABC-type sugar transport system periplasmic component	ugpB	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
YYD2_k127_1938054_2	1379270.AUXF01000001_gene2721	7.402e-16	81.0	COG2363@1|root,COG2363@2|Bacteria,1ZUWK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
YYD2_k127_1938054_0	1382306.JNIM01000001_gene4084	1.273e-28	132.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
YYD2_k127_1938054_1	1123054.KB907705_gene2416	2.25e-17	96.0	COG0729@1|root,COG0729@2|Bacteria,1QVUN@1224|Proteobacteria,1T2JF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD2_k127_19404_3	1120968.AUBX01000017_gene1904	7.067e-36	149.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,47XWC@768503|Cytophagia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
YYD2_k127_19404_2	1123392.AQWL01000003_gene209	1.103e-67	244.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,1KSNJ@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer,NTP_transferase
YYD2_k127_19404_0	1195236.CTER_1970	4.47e-90	318.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_19404_1	1297865.APJD01000003_gene6216	9.966e-87	318.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U3N3@28211|Alphaproteobacteria,3K615@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_19404_4	575540.Isop_3306	2.789e-28	131.0	COG0438@1|root,COG0438@2|Bacteria,2IY70@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_1945104_2	1122179.KB890436_gene1409	8.02e-35	145.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YYD2_k127_1945104_4	880073.Calab_3363	0.0003556	52.0	COG3291@1|root,COG3386@1|root,COG4733@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4,3.2.1.89,4.2.2.3	ko:K01179,ko:K01224,ko:K01729	ko00051,ko00500,ko01100,map00051,map00500,map01100	-	R03706,R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CHU_C,DUF1566,HATPase_c,HTH_18,HisKA,PKD,Reg_prop,Response_reg
YYD2_k127_1945104_1	526222.Desal_2833	1.248e-81	276.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MB6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YYD2_k127_1945104_0	927658.AJUM01000034_gene68	1.708e-167	551.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,3XJPB@558415|Marinilabiliaceae	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD2_k127_1945202_2	398767.Glov_3063	3.865e-111	373.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
YYD2_k127_1945202_7	1121127.JAFA01000070_gene6110	1.353e-12	79.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,1KA6B@119060|Burkholderiaceae	28216|Betaproteobacteria	O	hydrogenase expression formation protein	hypC1	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
YYD2_k127_1945202_0	401526.TcarDRAFT_0344	9.034e-212	692.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,4H3B6@909932|Negativicutes	909932|Negativicutes	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
YYD2_k127_1945202_6	646529.Desaci_2870	6.263e-14	83.0	COG0680@1|root,COG0680@2|Bacteria,1V7KQ@1239|Firmicutes,24IHW@186801|Clostridia	186801|Clostridia	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
YYD2_k127_1945202_1	237368.SCABRO_02487	9.697e-130	437.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
YYD2_k127_1945202_5	237368.SCABRO_02488	3.729e-77	271.0	COG1941@1|root,COG1941@2|Bacteria,2IXWB@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
YYD2_k127_1945202_3	552811.Dehly_0927	1.218e-94	317.0	COG0543@1|root,COG2204@1|root,COG0543@2|Bacteria,COG2204@2|Bacteria,2G7HU@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.3	ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YYD2_k127_1945202_4	572477.Alvin_0810	2.954e-77	272.0	COG1143@1|root,COG1143@2|Bacteria,1QVAQ@1224|Proteobacteria,1T4SQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
YYD2_k127_1976096_0	926560.KE387023_gene2049	1.406e-115	394.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
YYD2_k127_1997639_1	1267535.KB906767_gene3177	1.45e-184	595.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YYD2_k127_1997639_5	696281.Desru_1009	1.441e-43	184.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,261YZ@186807|Peptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
YYD2_k127_1997639_0	264732.Moth_0531	3.384e-270	870.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD2_k127_1997639_2	580331.Thit_0619	5.664e-175	557.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YYD2_k127_1997639_3	760568.Desku_0397	2.611e-92	306.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,260UI@186807|Peptococcaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YYD2_k127_1997639_4	1340493.JNIF01000003_gene2845	2.33e-63	234.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YYD2_k127_2001696_3	1121378.KB899725_gene93	2.723e-15	84.0	COG0746@1|root,COG0746@2|Bacteria,1WIB6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YYD2_k127_2001696_0	234267.Acid_3899	1.92e-22	108.0	COG1959@1|root,COG1959@2|Bacteria,3Y8ZE@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YYD2_k127_2001696_4	1158150.KB906246_gene1912	6.146e-12	78.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Nitrate_red_del
YYD2_k127_2001696_2	634497.HAH_4413	2.153e-15	88.0	arCOG04198@1|root,arCOG04198@2157|Archaea,2XU58@28890|Euryarchaeota,23UGH@183963|Halobacteria	183963|Halobacteria	Q	TIGRFAM DMSO reductase family type II enzyme, heme b subunit	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
YYD2_k127_2001696_1	1255043.TVNIR_1120	7.56e-17	82.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
YYD2_k127_2012751_1	1519464.HY22_07730	3.488e-16	93.0	COG1572@1|root,COG1572@2|Bacteria,1FEWM@1090|Chlorobi	1090|Chlorobi	S	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
YYD2_k127_2012751_0	370438.PTH_2122	0.0	1053.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,2602D@186807|Peptococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD2_k127_2030302_0	1446473.JHWH01000017_gene3971	7.752e-140	476.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2PUGP@265|Paracoccus	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YYD2_k127_2030302_2	1304275.C41B8_16929	8.679e-50	188.0	COG0671@1|root,COG0671@2|Bacteria,1RGM4@1224|Proteobacteria	1224|Proteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD2_k127_2030302_1	1385935.N836_32435	2.671e-78	282.0	COG0697@1|root,COG0697@2|Bacteria,1G4U5@1117|Cyanobacteria,1HFB2@1150|Oscillatoriales	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD2_k127_2030302_3	479432.Sros_5880	2.452e-35	138.0	2E5J0@1|root,330AB@2|Bacteria,2I805@201174|Actinobacteria,4ERAW@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2030302_4	521674.Plim_1471	3.093e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,2J0SR@203682|Planctomycetes	203682|Planctomycetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD2_k127_2030302_7	1379698.RBG1_1C00001G0055	1.146e-19	100.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YYD2_k127_2030302_5	479434.Sthe_1445	1.457e-30	129.0	COG0558@1|root,COG0558@2|Bacteria,2G7HQ@200795|Chloroflexi,27YAM@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YYD2_k127_2030302_8	96561.Dole_1813	1.232e-13	73.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria,42R19@68525|delta/epsilon subdivisions,2WMNW@28221|Deltaproteobacteria,2MMR8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
YYD2_k127_2065551_1	1121430.JMLG01000010_gene185	3.435e-78	270.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,2600U@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
YYD2_k127_2065551_2	497964.CfE428DRAFT_0598	1.147e-73	252.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	PFAM glutamine amidotransferase class-I	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YYD2_k127_2065551_0	443144.GM21_1804	3.764e-139	471.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YYD2_k127_2065551_3	867903.ThesuDRAFT_00086	3.68e-43	169.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WCFS@538999|Clostridiales incertae sedis	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
YYD2_k127_2068149_0	1379270.AUXF01000001_gene2652	2.67e-81	277.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_2068149_1	861299.J421_4355	5.843e-66	248.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2071697_3	56780.SYN_02948	1.462e-45	168.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD2_k127_2071697_0	1304885.AUEY01000002_gene358	0.0	1301.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI2Z@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD2_k127_2071697_1	1304885.AUEY01000002_gene357	2.756e-153	499.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MJ5Q@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
YYD2_k127_2071697_2	290317.Cpha266_2140	2.884e-60	213.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
YYD2_k127_2088614_2	1123508.JH636441_gene3757	3e-19	87.0	COG4877@1|root,COG4877@2|Bacteria,2J4M8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2088614_0	745411.B3C1_13254	1.54e-102	341.0	COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,1RUQU@1236|Gammaproteobacteria,1J7WG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD2_k127_2088614_1	1396141.BATP01000007_gene5722	1.691e-52	193.0	COG0500@1|root,COG2226@2|Bacteria,46V7M@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD2_k127_2088614_3	710686.Mycsm_02186	5.547e-18	91.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,2GJDH@201174|Actinobacteria,233NI@1762|Mycobacteriaceae	201174|Actinobacteria	ET	phosphoserine phosphatase	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
YYD2_k127_2091364_0	471852.Tcur_3271	4.923e-126	419.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4EFSX@85012|Streptosporangiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD2_k127_2091364_1	1123284.KB899045_gene2414	0.0008996	43.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	ykfB	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YYD2_k127_2149713_4	1411123.JQNH01000001_gene2054	4.164e-16	91.0	COG2864@1|root,COG2864@2|Bacteria,1R5NK@1224|Proteobacteria,2U2HQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Ni_hydr_CYTB
YYD2_k127_2149713_0	563192.HMPREF0179_02334	1.444e-139	461.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2M9RV@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD2_k127_2149713_2	880073.Calab_1379	3.356e-119	393.0	COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YYD2_k127_2149713_3	1254432.SCE1572_22330	3.485e-27	123.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
YYD2_k127_2149713_1	1121468.AUBR01000058_gene881	1.671e-137	453.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YYD2_k127_2151453_4	478741.JAFS01000002_gene956	2.57e-06	50.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia,37GDF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
YYD2_k127_2151453_1	237368.SCABRO_03012	2.542e-51	190.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2151453_0	671143.DAMO_0350	7.05e-59	222.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2151453_2	330214.NIDE2490	7.231e-45	171.0	29ZH8@1|root,30MGZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2151453_3	247490.KSU1_B0650	8.727e-23	99.0	28MEN@1|root,2ZASA@2|Bacteria,2IZ1H@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2153692_0	880073.Calab_1111	1.967e-114	402.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
YYD2_k127_2153692_1	511051.CSE_05130	5.771e-58	211.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
YYD2_k127_2153692_2	644968.DFW101_3632	9.285e-11	64.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,42NEI@68525|delta/epsilon subdivisions,2WJP9@28221|Deltaproteobacteria,2M8HK@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
YYD2_k127_2154274_3	880073.Calab_0061	9.57e-67	245.0	COG2876@1|root,COG2876@2|Bacteria,2NNPG@2323|unclassified Bacteria	2|Bacteria	E	PFAM DAHP synthetase I KDSA	ccmA1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YYD2_k127_2154274_0	370438.PTH_2544	3.883e-95	336.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae	186801|Clostridia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD2_k127_2154274_8	2325.TKV_c05020	1.326e-17	97.0	2C0MY@1|root,2ZC2Z@2|Bacteria,1V9XB@1239|Firmicutes,24PCF@186801|Clostridia,42G5R@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2154274_1	671143.DAMO_1215	1.685e-92	312.0	COG0524@1|root,COG0524@2|Bacteria,2NP1T@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
YYD2_k127_2154274_7	517418.Ctha_0064	1.262e-29	123.0	COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi	1090|Chlorobi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
YYD2_k127_2154274_4	909663.KI867150_gene1333	2.222e-64	233.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2MQBX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YYD2_k127_2154274_2	1125863.JAFN01000001_gene2073	1.984e-80	285.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD2_k127_2154274_6	1379698.RBG1_1C00001G0287	2.833e-34	150.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
YYD2_k127_2154274_5	1283299.AUKG01000002_gene4917	9.433e-39	157.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
YYD2_k127_2155381_2	208444.JNYY01000006_gene7037	3.869e-06	56.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD2_k127_2155381_1	477974.Daud_0351	2.297e-54	205.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,260TJ@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD2_k127_2155381_0	1144275.COCOR_01334	8.951e-102	341.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YYD2_k127_2155852_0	391625.PPSIR1_09331	3.845e-45	184.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1532,iJN746.PP_3282	3HCDH,3HCDH_N
YYD2_k127_2159788_9	443143.GM18_0926	2.676e-08	57.0	COG4191@1|root,COG4191@2|Bacteria,1QUMH@1224|Proteobacteria,42MM2@68525|delta/epsilon subdivisions,2WJBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD2_k127_2159788_7	247490.KSU1_C1671	7.251e-45	180.0	COG1538@1|root,COG1538@2|Bacteria,2IZPU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD2_k127_2159788_2	886293.Sinac_2526	9.967e-101	352.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
YYD2_k127_2159788_0	886293.Sinac_2525	1.541e-215	682.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YYD2_k127_2159788_1	1379698.RBG1_1C00001G0078	4.54e-118	409.0	COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547,iB21_1397.B21_00525,iECBD_1354.ECBD_3087,iECB_1328.ECB_00536,iECD_1391.ECD_00536	ACR_tran
YYD2_k127_2159788_5	404589.Anae109_1654	4.31e-59	209.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,2Z0UJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
YYD2_k127_2159788_8	1191523.MROS_1345	4.871e-35	139.0	COG2314@1|root,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
YYD2_k127_2159788_4	489825.LYNGBM3L_30420	1.772e-64	240.0	COG0500@1|root,COG2226@2|Bacteria,1GQ2Q@1117|Cyanobacteria	1117|Cyanobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
YYD2_k127_2159788_3	1499967.BAYZ01000119_gene3214	4.155e-81	282.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
YYD2_k127_2159788_6	909663.KI867150_gene885	5.039e-52	187.0	COG0574@1|root,COG1669@1|root,COG0574@2|Bacteria,COG1669@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MR7X@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
YYD2_k127_2161852_0	443143.GM18_1345	2.503e-66	234.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YYD2_k127_2161852_1	234267.Acid_3541	2.106e-11	77.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria	57723|Acidobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2167897_5	1382358.JHVN01000001_gene1050	1.339e-46	171.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,21WGS@150247|Anoxybacillus	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YYD2_k127_2167897_0	290397.Adeh_1230	0.0	1022.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria,2YUIB@29|Myxococcales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
YYD2_k127_2167897_3	867845.KI911784_gene1787	3.732e-153	492.0	COG2718@1|root,COG2718@2|Bacteria,2G6DB@200795|Chloroflexi,375C8@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
YYD2_k127_2167897_1	1144275.COCOR_06337	7.637e-195	619.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,42MYY@68525|delta/epsilon subdivisions,2WJ6V@28221|Deltaproteobacteria,2YUGF@29|Myxococcales	28221|Deltaproteobacteria	S	SpoVR like protein	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
YYD2_k127_2167897_4	401053.AciPR4_2165	8.355e-140	464.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
YYD2_k127_2167897_2	671143.DAMO_2494	9.074e-173	562.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD2_k127_2167897_6	1068978.AMETH_2873	1.65e-31	134.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4E2QQ@85010|Pseudonocardiales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YYD2_k127_2167897_7	1242864.D187_003254	1.388e-15	79.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2YVCN@29|Myxococcales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YYD2_k127_2168106_4	485915.Dret_1750	9.414e-43	164.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
YYD2_k127_2168106_1	398767.Glov_0521	9.293e-106	365.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,43SUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YYD2_k127_2168106_2	1232410.KI421415_gene3101	1.53e-75	266.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,43RXT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Ferrochelatase	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
YYD2_k127_2168106_0	404589.Anae109_1129	5.02e-146	477.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2WMB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YYD2_k127_2168106_3	338963.Pcar_0769	3.655e-61	220.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,43S1P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
YYD2_k127_2169924_5	913325.N799_08000	2.371e-08	60.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1X5ZA@135614|Xanthomonadales	135614|Xanthomonadales	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
YYD2_k127_2169924_2	1121468.AUBR01000034_gene1378	1.126e-113	391.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
YYD2_k127_2169924_4	290397.Adeh_1665	3.471e-50	193.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_2169924_3	880073.Calab_0217	4.939e-110	372.0	COG1250@1|root,COG1250@2|Bacteria,2NP11@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbdA	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YYD2_k127_2169924_0	1379698.RBG1_1C00001G1459	3.01e-150	486.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD2_k127_2169924_1	246194.CHY_1350	1.436e-132	433.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
YYD2_k127_2170657_0	562970.Btus_2226	1.757e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,278K5@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_2170657_2	264732.Moth_2363	0.0004867	52.0	COG5662@1|root,COG5662@2|Bacteria,1VC8Y@1239|Firmicutes,24NRN@186801|Clostridia,42GY2@68295|Thermoanaerobacterales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
YYD2_k127_2170657_1	1209989.TepiRe1_0358	8.029e-11	74.0	COG1664@1|root,COG1664@2|Bacteria,1VBC3@1239|Firmicutes,24NSR@186801|Clostridia,42I1I@68295|Thermoanaerobacterales	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2172887_2	1125863.JAFN01000001_gene2732	3.247e-10	64.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YYD2_k127_2172887_1	1125863.JAFN01000001_gene2731	4.315e-28	117.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD2_k127_2172887_0	483219.LILAB_09155	3.856e-57	226.0	COG1835@1|root,COG1835@2|Bacteria,1RFAU@1224|Proteobacteria,434WP@68525|delta/epsilon subdivisions,2WZ7M@28221|Deltaproteobacteria,2Z1I5@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
YYD2_k127_2172887_3	1123229.AUBC01000013_gene2524	6.513e-07	61.0	COG1073@1|root,COG1073@2|Bacteria,1N8YB@1224|Proteobacteria,2TVHE@28211|Alphaproteobacteria,3JXFB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
YYD2_k127_2173217_1	1356854.N007_04105	7.655e-67	234.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,277ZQ@186823|Alicyclobacillaceae	91061|Bacilli	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD2_k127_2173217_0	1048834.TC41_1959	1.1e-108	361.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,27844@186823|Alicyclobacillaceae	91061|Bacilli	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
YYD2_k127_2173217_2	529709.PYCH_10870	3.031e-31	137.0	COG0697@1|root,arCOG00271@2157|Archaea,2XVTF@28890|Euryarchaeota,243ED@183968|Thermococci	183968|Thermococci	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD2_k127_2182583_2	1379698.RBG1_1C00001G1725	6.982e-15	76.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
YYD2_k127_2182583_0	378806.STAUR_2268	3.457e-108	361.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,42QN8@68525|delta/epsilon subdivisions,2WM0P@28221|Deltaproteobacteria,2YUBY@29|Myxococcales	28221|Deltaproteobacteria	C	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
YYD2_k127_2182583_1	391615.ABSJ01000032_gene712	1.69e-58	209.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD2_k127_2187331_1	205918.Psyr_2021	5.439e-20	93.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Z5Z5@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
YYD2_k127_2187331_0	45351.EDO49675	5.863e-217	686.0	COG0334@1|root,KOG2250@2759|Eukaryota,38GEK@33154|Opisthokonta,3BKKN@33208|Metazoa	33208|Metazoa	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YYD2_k127_2187331_3	671143.DAMO_1635	4.375e-07	63.0	COG0392@1|root,COG0392@2|Bacteria,2NPJC@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD2_k127_2187331_2	158190.SpiGrapes_2254	4.568e-08	64.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4983,FIVAR,Hemopexin,Laminin_G_3,PA14,Phosphodiest
YYD2_k127_2188049_1	756883.Halar_1502	5.642e-74	274.0	COG1165@1|root,arCOG04611@2157|Archaea	2157|Archaea	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
YYD2_k127_2188049_2	235909.GK2876	1.18e-62	235.0	COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4H9K8@91061|Bacilli,1WEK9@129337|Geobacillus	91061|Bacilli	H	Catalyzes the conversion of chorismate to isochorismate	menF	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30830	Chorismate_bind
YYD2_k127_2188049_0	247490.KSU1_B0348	5.621e-86	293.0	COG0501@1|root,COG0501@2|Bacteria,2J512@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD2_k127_2188049_3	426117.M446_1754	1.385e-06	61.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,1JSRD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
YYD2_k127_2188616_4	1123320.KB889683_gene2044	1.471e-14	83.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
YYD2_k127_2188616_2	207559.Dde_0667	1.756e-52	200.0	COG3021@1|root,COG3021@2|Bacteria,1NJVF@1224|Proteobacteria,430DR@68525|delta/epsilon subdivisions,2WVVN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YYD2_k127_2188616_3	96561.Dole_2043	2.113e-26	126.0	COG1800@1|root,COG2885@1|root,COG3420@1|root,COG1800@2|Bacteria,COG2885@2|Bacteria,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2188616_0	880073.Calab_0341	2.662e-182	587.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YYD2_k127_2188616_1	518766.Rmar_0251	1.731e-87	298.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1FIQK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
YYD2_k127_2192552_0	696369.KI912183_gene2326	7.472e-251	833.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,2600Y@186807|Peptococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YYD2_k127_2192552_1	1205680.CAKO01000006_gene3328	7.177e-78	274.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2192552_2	1089550.ATTH01000001_gene1005	3.93e-25	118.0	COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EO	Trypsin-like serine protease	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
YYD2_k127_2201562_1	1123489.AUAN01000004_gene1826	1.021e-32	143.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,4H3GY@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YYD2_k127_2201562_0	264732.Moth_2008	1.05e-154	505.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YYD2_k127_2201562_2	47763.JNZA01000004_gene3732	3.72e-06	50.0	COG0154@1|root,COG0154@2|Bacteria,2GN7F@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD2_k127_2202314_1	639282.DEFDS_1228	4.344e-172	545.0	COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres	200930|Deferribacteres	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD2_k127_2202314_2	1487953.JMKF01000007_gene5870	5.308e-146	479.0	COG0439@1|root,COG0439@2|Bacteria,1G1M0@1117|Cyanobacteria,1H87J@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD2_k127_2202314_3	1304885.AUEY01000058_gene2314	4.986e-09	67.0	COG4770@1|root,COG5016@1|root,COG4770@2|Bacteria,COG5016@2|Bacteria,1P6RE@1224|Proteobacteria,43BQE@68525|delta/epsilon subdivisions,2X71H@28221|Deltaproteobacteria,2MHKV@213118|Desulfobacterales	28221|Deltaproteobacteria	CI	Conserved carboxylase domain	-	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
YYD2_k127_2202314_0	997346.HMPREF9374_0342	1.378e-196	631.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,27B33@186824|Thermoactinomycetaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YYD2_k127_2204689_2	1499967.BAYZ01000063_gene6022	9.637e-37	156.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
YYD2_k127_2204689_4	439235.Dalk_2132	1.504e-15	92.0	COG3291@1|root,COG3292@1|root,COG3291@2|Bacteria,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria,2MNQR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
YYD2_k127_2204689_1	518766.Rmar_0572	7.224e-57	220.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1FIXH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
YYD2_k127_2204689_3	1385513.N780_10410	1.275e-16	87.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,2YA96@289201|Pontibacillus	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YYD2_k127_2204689_6	378806.STAUR_6271	1.126e-06	57.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,STAS,STAS_2
YYD2_k127_2204689_0	1042156.CXIVA_02590	1.625e-59	220.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,36E4H@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YYD2_k127_2204689_5	1219072.VHA01S_003_02900	1.915e-14	82.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XTH5@135623|Vibrionales	135623|Vibrionales	D	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
YYD2_k127_2216205_1	194867.ALBQ01000018_gene2463	6.739e-17	81.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2K16Q@204457|Sphingomonadales	204457|Sphingomonadales	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD2_k127_2223487_0	1379698.RBG1_1C00001G1403	2.509e-118	397.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
YYD2_k127_2223487_1	443143.GM18_3797	1.428e-37	145.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
YYD2_k127_2226520_4	1089550.ATTH01000001_gene1072	2.841e-08	66.0	COG1409@1|root,COG1572@1|root,COG4733@1|root,COG1409@2|Bacteria,COG1572@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4,3.4.21.96	ko:K01179,ko:K01361,ko:K13277,ko:K21449	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	GH5,GH9	-	Amidase_2,DUF1735,Glucosaminidase,Laminin_G_3
YYD2_k127_2226520_0	247490.KSU1_B0344	9.425e-63	226.0	2A417@1|root,2ZPBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2226520_3	429009.Adeg_0089	1.9e-09	67.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42GIC@68295|Thermoanaerobacterales	186801|Clostridia	K	RNA polymerase sigma factor	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_2226520_1	56110.Oscil6304_3156	2.525e-36	160.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G0BI@1117|Cyanobacteria,1H9XU@1150|Oscillatoriales	1117|Cyanobacteria	S	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
YYD2_k127_2226520_2	1121373.KB903621_gene1961	9.226e-13	80.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406,ko:K07004	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	Calx-beta,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3
YYD2_k127_2231623_1	479434.Sthe_2271	3.761e-19	100.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_2231623_0	290397.Adeh_2455	1.409e-67	241.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YYD2_k127_2237259_0	1340493.JNIF01000003_gene3002	6.151e-14	72.0	COG1228@1|root,COG1228@2|Bacteria,3Y6WV@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD2_k127_2253133_1	1123073.KB899241_gene3242	1.502e-12	74.0	COG1572@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,1SUAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2253133_2	497964.CfE428DRAFT_5961	2.88e-07	61.0	COG2931@1|root,COG3210@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735,ko:K15125,ko:K20276	ko02024,ko05100,ko05133,map02024,map05100,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Big_3_2,DUF11,HemolysinCabind
YYD2_k127_2253133_0	448385.sce0310	5.028e-105	352.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
YYD2_k127_2269945_1	234267.Acid_3938	1.216e-58	233.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD2_k127_2269945_0	266117.Rxyl_2946	4.499e-140	482.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
YYD2_k127_2269945_2	459349.CLOAM1721	0.000452	53.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD2_k127_2272698_3	1304883.KI912532_gene904	4.232e-82	276.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KV40@206389|Rhodocyclales	206389|Rhodocyclales	P	COG1613 ABC-type sulfate transport system, periplasmic component	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
YYD2_k127_2272698_2	717785.HYPMC_0718	2.831e-110	364.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2TTET@28211|Alphaproteobacteria,3N61W@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Sulfate ABC transporter inner membrane subunit CysT	cysT	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
YYD2_k127_2272698_1	261292.Nit79A3_0993	2.384e-111	385.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,3729U@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
YYD2_k127_2272698_0	1266925.JHVX01000003_gene616	9.403e-129	435.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,372VB@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
YYD2_k127_2278303_4	1380390.JIAT01000016_gene5519	3.026e-12	75.0	COG1807@1|root,COG1807@2|Bacteria,2IITJ@201174|Actinobacteria,4CR1K@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_2278303_0	313628.LNTAR_10061	6.38e-197	632.0	COG0441@1|root,COG0441@2|Bacteria	2|Bacteria	J	threonyl-tRNA aminoacylation	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YYD2_k127_2278303_3	452637.Oter_1575	6.124e-52	205.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YYD2_k127_2278303_5	96561.Dole_0338	6.067e-10	67.0	2FHTG@1|root,349KR@2|Bacteria,1P1C2@1224|Proteobacteria,4318F@68525|delta/epsilon subdivisions,2WWJT@28221|Deltaproteobacteria,2MNZ8@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2278303_6	485913.Krac_8941	1.919e-07	57.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	DUF2087,HTH_20,HTH_5
YYD2_k127_2278303_2	635013.TherJR_0449	3.399e-85	292.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,24A44@186801|Clostridia,260HI@186807|Peptococcaceae	186801|Clostridia	Q	Hypothetical methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YYD2_k127_2278303_1	671143.DAMO_1876	8.217e-132	437.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	nla6	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_229656_2	316067.Geob_2839	3.695e-29	119.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,43T3U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD2_k127_229656_3	379066.GAU_1296	5.663e-20	95.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_229656_0	1125863.JAFN01000001_gene534	4.606e-32	138.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD2_k127_229656_1	471853.Bcav_0823	1.346e-29	126.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
YYD2_k127_229656_4	394221.Mmar10_0616	2.678e-09	61.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,43WNZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YYD2_k127_2309472_0	443143.GM18_1617	4.355e-146	480.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YYD2_k127_23223_1	637389.Acaty_c2461	1.962e-15	84.0	COG1309@1|root,COG1309@2|Bacteria,1Q9E2@1224|Proteobacteria,1TD5N@1236|Gammaproteobacteria,2NCC3@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
YYD2_k127_23223_0	768706.Desor_2109	1.021e-105	357.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,2601Y@186807|Peptococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YYD2_k127_2323808_1	1232437.KL662018_gene599	9.627e-44	179.0	COG0596@1|root,COG0596@2|Bacteria,1NEZY@1224|Proteobacteria,42WGF@68525|delta/epsilon subdivisions,2WSB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2323808_5	270374.MELB17_11228	0.0005606	53.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,465SG@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
YYD2_k127_2323808_4	406552.NJ7G_2412	0.0004256	54.0	COG4885@1|root,COG5276@1|root,arCOG02565@2157|Archaea,arCOG04478@2157|Archaea,2XV6J@28890|Euryarchaeota,23SNQ@183963|Halobacteria	183963|Halobacteria	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YYD2_k127_2323808_0	945713.IALB_0602	9.051e-144	478.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
YYD2_k127_2323808_3	1211815.CBYP010000038_gene2177	1.554e-21	109.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4ERY0@85013|Frankiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
YYD2_k127_2323808_2	324602.Caur_0716	3.303e-33	144.0	COG1404@1|root,COG1404@2|Bacteria,2G87D@200795|Chloroflexi,377KU@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_2325779_0	1121468.AUBR01000003_gene616	4.639e-189	611.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,42EUK@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD2_k127_2325779_6	324057.Pjdr2_3378	7.225e-05	51.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,274UA@186822|Paenibacillaceae	91061|Bacilli	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
YYD2_k127_2325779_1	1110502.TMO_1129	4.758e-145	472.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2JPIZ@204441|Rhodospirillales	204441|Rhodospirillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YYD2_k127_2325779_4	56780.SYN_02029	6.692e-25	116.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MS94@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	LigT like Phosphoesterase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YYD2_k127_2325779_2	379066.GAU_1122	3.35e-74	272.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YYD2_k127_2325779_5	1379698.RBG1_1C00001G1885	1.319e-22	110.0	COG1267@1|root,COG1267@2|Bacteria	2|Bacteria	I	phosphatidylglycerophosphatase activity	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
YYD2_k127_2325779_3	1693.BMIN_0997	1.148e-63	224.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CZRI@85004|Bifidobacteriales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
YYD2_k127_2325779_7	1121918.ARWE01000001_gene240	0.0002643	43.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,43SPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YYD2_k127_2344536_1	661478.OP10G_2024	1.846e-34	141.0	2CEN7@1|root,2Z9XA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2344536_0	1232410.KI421413_gene484	1.099e-45	169.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,437CT@68525|delta/epsilon subdivisions,2XA0U@28221|Deltaproteobacteria,43VKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YYD2_k127_2344536_2	1379698.RBG1_1C00001G0468	4.066e-27	113.0	COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria	2|Bacteria	S	DinB family	yrdA	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD2_k127_2344934_3	1298593.TOL_0098	4.001e-10	73.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XJIR@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_2344934_0	391615.ABSJ01000054_gene1467	1.869e-54	199.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1JAIZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
YYD2_k127_2344934_1	439235.Dalk_2812	1.244e-39	160.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2MHMR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_2344934_2	865937.Gilli_0819	5.109e-28	121.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	2.6.1.9	ko:K00817,ko:K11777	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	HAD_2,Hydrolase,Hydrolase_like
YYD2_k127_2359241_2	1379698.RBG1_1C00001G0503	4.745e-62	234.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
YYD2_k127_2359241_4	348780.NP_1050A	2.199e-26	124.0	COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eIF-2B alpha beta delta subunits family	tif2Ba	-	-	-	-	-	-	-	-	-	-	-	IF-2B,NUDIX
YYD2_k127_2359241_0	706587.Desti_2694	1.518e-135	441.0	COG0057@1|root,COG0057@2|Bacteria,1N2N1@1224|Proteobacteria	1224|Proteobacteria	G	Glyceraldehyde-3-phosphate dehydrogenase	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
YYD2_k127_2359241_1	945713.IALB_1339	1.146e-73	260.0	COG0302@1|root,COG0302@2|Bacteria	2|Bacteria	H	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
YYD2_k127_2359241_3	349161.Dred_1955	3.043e-30	133.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,261DN@186807|Peptococcaceae	186801|Clostridia	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YYD2_k127_2359241_5	301.JNHE01000012_gene1434	7.107e-16	90.0	COG0642@1|root,COG0745@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1YE0H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
YYD2_k127_2359747_0	1500890.JQNL01000001_gene2346	5.688e-59	212.0	2A5P5@1|root,30UDZ@2|Bacteria,1RHAP@1224|Proteobacteria,1SXHY@1236|Gammaproteobacteria,1X69H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2359747_1	671143.DAMO_2920	2.09e-23	106.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2359747_2	290397.Adeh_3744	1.487e-11	64.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YYD2_k127_240992_5	1379698.RBG1_1C00001G0356	6.424e-55	210.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
YYD2_k127_240992_1	1173025.GEI7407_0274	1.548e-104	348.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1H9Q3@1150|Oscillatoriales	1117|Cyanobacteria	M	NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD2_k127_240992_3	479434.Sthe_0859	1.307e-83	301.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,27XQE@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_240992_0	1089550.ATTH01000001_gene217	2.584e-148	474.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD2_k127_240992_2	945713.IALB_0745	5.67e-88	310.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.83	ko:K00721,ko:K03820	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	CN_hydrolase,Glycos_transf_2
YYD2_k127_240992_4	1499967.BAYZ01000063_gene6022	2.599e-73	266.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
YYD2_k127_2415083_0	290397.Adeh_3048	5.878e-188	608.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria	1224|Proteobacteria	T	flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
YYD2_k127_2415083_1	404589.Anae109_2917	4.973e-51	185.0	COG3576@1|root,COG3576@2|Bacteria,1PT74@1224|Proteobacteria,432EH@68525|delta/epsilon subdivisions,2WXW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2415083_2	404589.Anae109_2915	8.782e-15	74.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2420599_2	880073.Calab_2082	8.955e-10	64.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
YYD2_k127_2420599_0	103690.17129820	8.815e-103	341.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria,1HICK@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
YYD2_k127_2420599_1	1303518.CCALI_00760	1.701e-35	150.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,COesterase,Esterase,Peptidase_S9
YYD2_k127_2421837_1	861299.J421_4358	2.094e-50	192.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_2421837_0	861299.J421_4357	1.367e-53	202.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_2440349_0	448385.sce1143	7.979e-07	63.0	COG3210@1|root,COG3210@2|Bacteria,1QW1H@1224|Proteobacteria	1224|Proteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2443918_2	861299.J421_2741	1.939e-20	96.0	COG2332@1|root,COG2332@2|Bacteria,1ZTNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
YYD2_k127_2443918_0	671143.DAMO_1588	2.048e-177	578.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564	-	ko:K02198,ko:K04016	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YYD2_k127_2443918_3	469383.Cwoe_4477	0.0002978	51.0	2A2D1@1|root,30QQ1@2|Bacteria,2HRBZ@201174|Actinobacteria,4CT9D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2443918_1	1125863.JAFN01000001_gene3012	7.063e-54	199.0	COG1131@1|root,COG1131@2|Bacteria,1RGM1@1224|Proteobacteria,43ADE@68525|delta/epsilon subdivisions,2X5TA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
YYD2_k127_2445822_3	1242864.D187_005895	1.225e-36	146.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2WVFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
YYD2_k127_2445822_2	1379698.RBG1_1C00001G0322	1.507e-54	214.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
YYD2_k127_2445822_4	1043205.AFYF01000026_gene404	2.031e-33	147.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4FEM5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
YYD2_k127_2445822_0	269799.Gmet_3041	2.758e-118	396.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,43TYK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_2445822_1	945713.IALB_2784	9.7e-99	353.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
YYD2_k127_2456245_6	1408473.JHXO01000001_gene2077	3.853e-50	188.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YYD2_k127_2456245_7	1304880.JAGB01000002_gene2055	2.144e-37	149.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD2_k127_2456245_11	518766.Rmar_0679	1.393e-12	80.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1FITY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Outer membrane lipoprotein	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
YYD2_k127_2456245_4	1278073.MYSTI_01494	2.821e-105	366.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2YUDC@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
YYD2_k127_2456245_10	1123257.AUFV01000008_gene543	1.849e-15	85.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1X5BW@135614|Xanthomonadales	135614|Xanthomonadales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
YYD2_k127_2456245_2	1123371.ATXH01000006_gene825	4.599e-142	477.0	COG1674@1|root,COG1674@2|Bacteria,2GHMR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YYD2_k127_2456245_0	1303518.CCALI_01905	5.173e-181	584.0	COG0499@1|root,COG0499@2|Bacteria	2|Bacteria	H	adenosylhomocysteinase activity	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YYD2_k127_2456245_1	1125863.JAFN01000001_gene892	5.565e-154	496.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YYD2_k127_2456245_5	1519464.HY22_02585	5.746e-87	314.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
YYD2_k127_2456245_8	1122939.ATUD01000020_gene2153	8.756e-26	124.0	COG2222@1|root,COG2222@2|Bacteria,2IN5A@201174|Actinobacteria,4CP71@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
YYD2_k127_2456245_3	273068.TTE2334	1.444e-133	447.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YYD2_k127_2456245_9	1379270.AUXF01000005_gene735	2.641e-21	96.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YYD2_k127_2456245_12	404589.Anae109_0156	1.794e-08	65.0	COG3716@1|root,COG3716@2|Bacteria,1P02J@1224|Proteobacteria,42RPH@68525|delta/epsilon subdivisions,2WNQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system mannose fructose sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
YYD2_k127_2457973_2	502025.Hoch_5457	5.201e-18	91.0	COG0511@1|root,COG0511@2|Bacteria	2|Bacteria	I	ligase activity, forming carbon-carbon bonds	accB	-	2.3.1.12,2.3.1.39,4.1.1.3	ko:K00627,ko:K00645,ko:K01572,ko:K02160	ko00010,ko00020,ko00061,ko00333,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00333,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R01626,R02569,R11671	RC00004,RC00039,RC00040,RC00367,RC02727,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01004,ko02000	3.B.1.1.1	-	-	Acyl_transf_1,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
YYD2_k127_2457973_0	502025.Hoch_5456	2.248e-253	792.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria,42P34@68525|delta/epsilon subdivisions,2WK9S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
YYD2_k127_2457973_1	880073.Calab_3241	1.88e-156	507.0	COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria	2|Bacteria	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD2_k127_2465387_4	945713.IALB_3080	8.183e-24	117.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD2_k127_2465387_5	880073.Calab_2401	8.082e-19	101.0	COG2374@1|root,COG2374@2|Bacteria,2NRB5@2323|unclassified Bacteria	2|Bacteria	G	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,LTD
YYD2_k127_2465387_2	596153.Alide_1109	1.442e-47	196.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,4AA8Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YYD2_k127_2465387_1	1123371.ATXH01000013_gene1529	5.289e-80	276.0	COG0152@1|root,COG0152@2|Bacteria,2GH07@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YYD2_k127_2465387_0	861299.J421_2989	8.429e-130	432.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YYD2_k127_2465387_3	1121287.AUMU01000006_gene3862	4.554e-30	125.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia,3ZQIN@59732|Chryseobacterium	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YYD2_k127_2467133_0	247490.KSU1_D0230	9.559e-53	209.0	COG2199@1|root,COG2203@1|root,COG3452@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria	2|Bacteria	T	CHASE	ytrP	-	2.7.7.65	ko:K02488,ko:K21009	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	CHASE,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS_3,PAS_8,Response_reg
YYD2_k127_2478320_3	1123277.KB893174_gene5986	3.033e-10	70.0	COG0671@1|root,COG0671@2|Bacteria,4NMQW@976|Bacteroidetes,47PHH@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD2_k127_2478320_2	748449.Halha_2392	1.088e-39	168.0	2DYZV@1|root,34BXN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2478320_0	1123368.AUIS01000024_gene950	4.612e-135	447.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,2NCJF@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD2_k127_2478320_1	1123368.AUIS01000024_gene949	3.124e-67	232.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD2_k127_24878_6	525368.HMPREF0591_4542	3.757e-16	84.0	COG0596@1|root,COG0596@2|Bacteria,2I26T@201174|Actinobacteria,233Q4@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5,3.5.1.101	ko:K01259,ko:K18457	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD2_k127_24878_4	1114959.SZMC14600_07883	2.598e-57	211.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DY3G@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YYD2_k127_24878_0	215803.DB30_8173	2.842e-212	673.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2YUS1@29|Myxococcales	28221|Deltaproteobacteria	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
YYD2_k127_24878_1	518766.Rmar_2461	6.423e-135	443.0	COG0477@1|root,COG2814@2|Bacteria,4PI8A@976|Bacteroidetes,1FJNM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_24878_2	316274.Haur_3284	1.83e-100	339.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G7R5@200795|Chloroflexi,375SY@32061|Chloroflexia	32061|Chloroflexia	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
YYD2_k127_24878_5	443143.GM18_4346	4.484e-48	184.0	COG2346@1|root,COG2346@2|Bacteria,1Q6FD@1224|Proteobacteria,4331P@68525|delta/epsilon subdivisions,2WXI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YYD2_k127_24878_3	266117.Rxyl_2941	5.308e-60	214.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
YYD2_k127_2494005_1	1123239.KB898624_gene1957	1.11e-53	211.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	addA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YYD2_k127_2494005_0	292459.STH2174	1.923e-67	261.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
YYD2_k127_2501773_0	64471.sync_1278	2.534e-95	332.0	COG1200@1|root,COG1200@2|Bacteria,1G17H@1117|Cyanobacteria,1GZ2C@1129|Synechococcus	1117|Cyanobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YYD2_k127_250417_0	2074.JNYD01000001_gene5812	2.559e-119	403.0	COG1073@1|root,COG1073@2|Bacteria,2H036@201174|Actinobacteria,4E1IG@85010|Pseudonocardiales	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4,Peptidase_S9
YYD2_k127_250417_1	929556.Solca_2518	3.264e-52	190.0	2CMS6@1|root,32SFE@2|Bacteria,4NWI0@976|Bacteroidetes,1IYER@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD2_k127_2506517_0	1070774.J07HN4v3_01500	5.409e-06	56.0	COG1525@1|root,arCOG03192@2157|Archaea,2XTIT@28890|Euryarchaeota,23RYX@183963|Halobacteria	183963|Halobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	nuc	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	LTD,SNase
YYD2_k127_2510792_2	1031711.RSPO_c02228	6.416e-19	98.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2VR4M@28216|Betaproteobacteria,1K2UH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
YYD2_k127_2510792_1	1499967.BAYZ01000050_gene2795	1.016e-34	151.0	COG3382@1|root,COG3382@2|Bacteria,2NPUN@2323|unclassified Bacteria	2|Bacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
YYD2_k127_2510792_0	1125863.JAFN01000001_gene2857	2.498e-56	216.0	COG3391@1|root,COG3391@2|Bacteria,1RJQF@1224|Proteobacteria,42VW9@68525|delta/epsilon subdivisions,2WRUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2511865_0	1120971.AUCA01000024_gene455	9.649e-55	209.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,277VQ@186823|Alicyclobacillaceae	91061|Bacilli	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
YYD2_k127_2511865_1	1095769.CAHF01000025_gene686	3.16e-17	93.0	COG2199@1|root,COG3614@1|root,COG2199@2|Bacteria,COG3614@2|Bacteria,1RGCV@1224|Proteobacteria,2WGZP@28216|Betaproteobacteria,47960@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF
YYD2_k127_2541758_1	1459636.NTE_02734	1.727e-05	55.0	arCOG11830@1|root,arCOG11830@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2541758_0	477974.Daud_1294	8.836e-30	134.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,262K6@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
YYD2_k127_2548048_1	232346.JHQL01000001_gene2168	3.238e-88	303.0	COG1158@1|root,COG1158@2|Bacteria,1PW77@1224|Proteobacteria,1RYAS@1236|Gammaproteobacteria,1XHRH@135619|Oceanospirillales	135619|Oceanospirillales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab
YYD2_k127_2548048_0	926569.ANT_18600	1.559e-91	312.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
YYD2_k127_2548146_0	665571.STHERM_c05440	2.192e-80	285.0	COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes	203691|Spirochaetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	rrp-2	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_2567628_1	1356852.N008_00175	4.287e-30	132.0	COG2931@1|root,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes,47RDD@768503|Cytophagia	976|Bacteroidetes	Q	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
YYD2_k127_2567628_0	1268237.G114_03903	3.224e-45	177.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YYD2_k127_258275_3	1254432.SCE1572_16370	6.841e-43	170.0	2A79N@1|root,30W69@2|Bacteria,1PHGN@1224|Proteobacteria,42ZJ6@68525|delta/epsilon subdivisions,2WUWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YYD2_k127_258275_0	880072.Desac_0158	8.079e-86	289.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MQD3@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
YYD2_k127_258275_4	1380390.JIAT01000013_gene283	4.28e-17	96.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4CSV6@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_258275_1	237368.SCABRO_02998	4.567e-60	220.0	COG1994@1|root,COG1994@2|Bacteria,2IZCZ@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YYD2_k127_258275_2	1047013.AQSP01000052_gene2600	1.029e-52	192.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD2_k127_2598394_1	1032480.MLP_53040	2.848e-125	409.0	COG2382@1|root,COG2382@2|Bacteria,2HJEA@201174|Actinobacteria,4DSCH@85009|Propionibacteriales	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
YYD2_k127_2598394_2	1246995.AFR_24945	3.295e-117	392.0	COG1181@1|root,COG1181@2|Bacteria,2HP1M@201174|Actinobacteria,4DHKT@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C
YYD2_k127_2598394_3	1386089.N865_08430	9.217e-93	315.0	COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4FFF6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD2_k127_2598394_0	1089550.ATTH01000001_gene1799	3.839e-215	689.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,4NGW0@976|Bacteroidetes,1FIUK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GCS2
YYD2_k127_2599158_1	1125863.JAFN01000001_gene2376	7.688e-20	93.0	COG1186@1|root,COG1186@2|Bacteria,1ND5C@1224|Proteobacteria,430VS@68525|delta/epsilon subdivisions,2WW3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
YYD2_k127_2599158_2	1041139.KB902713_gene4409	5.152e-07	61.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,4BCFW@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF977,Fic,HTH_24,HTH_DeoR,Penicillinase_R
YYD2_k127_2599158_0	502025.Hoch_6862	4.541e-178	569.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2YWA3@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
YYD2_k127_2601455_0	1254432.SCE1572_00795	1.096e-56	203.0	arCOG07238@1|root,34BTI@2|Bacteria,1P13S@1224|Proteobacteria,4354M@68525|delta/epsilon subdivisions,2WZFN@28221|Deltaproteobacteria,2Z21A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2601455_1	926560.KE387025_gene4075	2.175e-40	164.0	2B5RU@1|root,31YMF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD2_k127_2601455_2	522306.CAP2UW1_1799	1.822e-15	86.0	COG5485@1|root,COG5485@2|Bacteria,1N1VS@1224|Proteobacteria	1224|Proteobacteria	S	Ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD2_k127_2606571_0	665571.STHERM_c15850	1.024e-20	106.0	COG1596@1|root,COG1596@2|Bacteria,2J6A1@203691|Spirochaetes	203691|Spirochaetes	M	export protein	-	-	-	-	-	-	-	-	-	-	-	-	SLBB
YYD2_k127_2616588_0	1379698.RBG1_1C00001G1562	5.746e-153	508.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
YYD2_k127_2616588_1	861299.J421_2719	5.266e-101	342.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
YYD2_k127_2627671_1	1121920.AUAU01000012_gene2648	2.928e-72	253.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YYD2_k127_2627671_0	204669.Acid345_2603	9.203e-75	262.0	COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria,2JP3M@204432|Acidobacteriia	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD2_k127_2640418_5	404589.Anae109_0927	5.378e-16	79.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
YYD2_k127_2640418_1	629773.AORY01000004_gene39	3.781e-117	395.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,2K0AJ@204457|Sphingomonadales	204457|Sphingomonadales	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
YYD2_k127_2640418_4	1232410.KI421417_gene2753	4.991e-38	156.0	COG1877@1|root,COG1877@2|Bacteria,1PF7W@1224|Proteobacteria,42QT9@68525|delta/epsilon subdivisions,2WNR9@28221|Deltaproteobacteria,43UM2@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
YYD2_k127_2640418_0	555779.Dthio_PD2276	1.313e-172	552.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2MEE0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
YYD2_k127_2640418_2	713586.KB900536_gene51	9.883e-56	203.0	COG0438@1|root,COG0438@2|Bacteria,1RA8H@1224|Proteobacteria,1S3Y5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2640418_3	272123.Anacy_4407	3.189e-53	213.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
YYD2_k127_2648900_2	1033739.CAEU01000026_gene3118	1.204e-35	149.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,26ECU@186818|Planococcaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	iYO844.BSU37780	Aldedh
YYD2_k127_2648900_0	1158292.JPOE01000005_gene112	2.497e-47	179.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KKN2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YYD2_k127_2648900_1	1122604.JONR01000001_gene1849	1.606e-41	171.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1X9FU@135614|Xanthomonadales	135614|Xanthomonadales	I	Squalene/phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
YYD2_k127_2662064_2	1345697.M493_14010	1.381e-31	132.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,4HG0Q@91061|Bacilli,1WFP2@129337|Geobacillus	91061|Bacilli	P	Bacterial extracellular solute-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
YYD2_k127_2662064_1	240016.ABIZ01000001_gene1506	1.039e-53	201.0	COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,2IUID@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
YYD2_k127_2662064_0	1144275.COCOR_07236	1.805e-70	254.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,42NN3@68525|delta/epsilon subdivisions,2WJZP@28221|Deltaproteobacteria,2YYTX@29|Myxococcales	28221|Deltaproteobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
YYD2_k127_2662064_4	880073.Calab_2082	1.179e-07	61.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
YYD2_k127_2662064_3	1379698.RBG1_1C00001G1377	3.418e-15	83.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
YYD2_k127_2684497_2	479434.Sthe_0743	1.403e-30	122.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD2_k127_2684497_0	309799.DICTH_1698	2.541e-106	355.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_2684497_1	479434.Sthe_1990	1.368e-34	135.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YYD2_k127_2684497_3	153721.MYP_1747	0.0006973	45.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
YYD2_k127_2684499_0	935948.KE386495_gene1578	1.555e-265	828.0	COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia,42FYF@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
YYD2_k127_2684499_1	479434.Sthe_1990	1.646e-106	361.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
YYD2_k127_2684499_2	316274.Haur_1687	1.319e-27	115.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi,376EH@32061|Chloroflexia	32061|Chloroflexia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_268674_0	404589.Anae109_2424	6.272e-143	471.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
YYD2_k127_268674_1	290397.Adeh_3976	3.655e-64	228.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,42VZ2@68525|delta/epsilon subdivisions,2X8TC@28221|Deltaproteobacteria,2YYPQ@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
YYD2_k127_2686819_0	96561.Dole_1585	4.226e-93	326.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2MHW2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
YYD2_k127_2686819_2	243231.GSU2429	4.847e-41	164.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YYD2_k127_2686819_1	243231.GSU2614	1.288e-68	246.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,43UIB@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YYD2_k127_269465_3	1125863.JAFN01000001_gene3190	1.946e-08	57.0	COG2199@1|root,COG3706@2|Bacteria,1QUKY@1224|Proteobacteria,42NYY@68525|delta/epsilon subdivisions,2WKIY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
YYD2_k127_269465_2	635013.TherJR_2129	4.498e-36	144.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_269465_1	1379698.RBG1_1C00001G1071	1.35e-44	167.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD2_k127_269465_0	1254432.SCE1572_33210	6.479e-85	295.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2Z1M7@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
YYD2_k127_2698051_3	269799.Gmet_3417	6.335e-21	105.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
YYD2_k127_2698051_2	1041930.Mtc_1015	3.305e-34	145.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
YYD2_k127_2698051_0	1562701.BBOF01000071_gene2170	1.343e-56	211.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1K2CE@119060|Burkholderiaceae	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YYD2_k127_2698051_1	644966.Tmar_1040	1.419e-50	199.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WCHZ@538999|Clostridiales incertae sedis	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YYD2_k127_2709508_20	1379698.RBG1_1C00001G0226	3.303e-10	72.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
YYD2_k127_2709508_14	264732.Moth_2128	6.799e-37	150.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42GKK@68295|Thermoanaerobacterales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YYD2_k127_2709508_10	443143.GM18_1770	2.657e-89	319.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YYD2_k127_2709508_13	861299.J421_3581	6.112e-48	192.0	COG0284@1|root,COG0284@2|Bacteria,1ZTQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YYD2_k127_2709508_1	644282.Deba_2080	6.801e-158	513.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD2_k127_2709508_12	56780.SYN_00576	2.731e-57	219.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria,42RZA@68525|delta/epsilon subdivisions,2WNBP@28221|Deltaproteobacteria,2MRPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	WxcM-like, C-terminal	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
YYD2_k127_2709508_6	634956.Geoth_0303	2.83e-118	391.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1WHF3@129337|Geobacillus	91061|Bacilli	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD2_k127_2709508_9	1121017.AUFG01000017_gene2485	1.071e-89	306.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4FHF7@85021|Intrasporangiaceae	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	rfbB	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD2_k127_2709508_19	358823.DF19_26230	2.372e-19	101.0	COG0472@1|root,COG0472@2|Bacteria,2GMPP@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
YYD2_k127_2709508_2	1379698.RBG1_1C00001G1543	3.082e-153	496.0	COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YYD2_k127_2709508_7	1379698.RBG1_1C00001G1544	5.844e-91	316.0	COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria	2|Bacteria	T	Integral membrane sensor signal transduction histidine kinase	vicK	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
YYD2_k127_2709508_0	518766.Rmar_2518	5.719e-164	531.0	COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,1FIZY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
YYD2_k127_2709508_18	867903.ThesuDRAFT_02303	1.85e-24	120.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WCKY@538999|Clostridiales incertae sedis	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YYD2_k127_2709508_17	696281.Desru_0741	1.848e-26	123.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,261MZ@186807|Peptococcaceae	186801|Clostridia	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
YYD2_k127_2709508_16	246194.CHY_0724	5.717e-29	124.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
YYD2_k127_2709508_8	693977.Deipr_1630	2.205e-90	313.0	COG0777@1|root,COG0777@2|Bacteria,1WIB7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD2_k127_2709508_11	1111069.TCCBUS3UF1_2720	2.501e-60	234.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YYD2_k127_2709508_5	1379698.RBG1_1C00001G0864	4.456e-126	445.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
YYD2_k127_2709508_15	1131269.AQVV01000002_gene1187	9.269e-36	151.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	mnuA	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
YYD2_k127_2709508_4	643473.KB235930_gene4490	6.932e-147	478.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1G0T4@1117|Cyanobacteria,1HM63@1161|Nostocales	1117|Cyanobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
YYD2_k127_2709508_3	290397.Adeh_3707	1.206e-147	477.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
YYD2_k127_2709508_21	304371.MCP_2205	6.511e-07	57.0	COG1895@1|root,arCOG02123@2157|Archaea,2Y56Q@28890|Euryarchaeota,2NBDH@224756|Methanomicrobia	224756|Methanomicrobia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
YYD2_k127_2713284_5	203275.BFO_1016	4.059e-16	77.0	COG0432@1|root,COG0432@2|Bacteria,4NUS2@976|Bacteroidetes,2FW13@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD2_k127_2713284_1	114615.BRADO6457	1.537e-70	248.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,2U5FG@28211|Alphaproteobacteria,3JY4S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD2_k127_2713284_0	1379698.RBG1_1C00001G0119	6.931e-99	341.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2713284_4	1379698.RBG1_1C00001G0118	1.327e-49	185.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2713284_2	521674.Plim_3797	3.733e-63	226.0	28MYQ@1|root,2ZB5K@2|Bacteria,2IZUC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2713284_3	344747.PM8797T_23676	6.104e-61	217.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2719303_0	945713.IALB_1146	5.619e-191	601.0	COG3051@1|root,COG3051@2|Bacteria	2|Bacteria	C	citrate CoA-transferase activity	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
YYD2_k127_2728237_2	1379698.RBG1_1C00001G0591	2.914e-07	59.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin_3,DUF11,FlgD_ig
YYD2_k127_2728237_1	525904.Tter_1300	2.416e-57	211.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YYD2_k127_2728237_0	1226325.HMPREF1548_03407	3.866e-76	266.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,36DYK@31979|Clostridiaceae	186801|Clostridia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YYD2_k127_2738764_0	1242864.D187_001787	8.202e-80	283.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,2YTWJ@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YYD2_k127_276841_0	269799.Gmet_0776	2.836e-71	250.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_276841_1	1121934.AUDX01000013_gene1774	2.445e-15	87.0	COG1158@1|root,COG3204@1|root,COG1158@2|Bacteria,COG3204@2|Bacteria,2I94U@201174|Actinobacteria,4FN98@85023|Microbacteriaceae	201174|Actinobacteria	K	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
YYD2_k127_278852_6	644966.Tmar_1010	1.025e-47	189.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WCSG@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
YYD2_k127_278852_8	1382306.JNIM01000001_gene1337	2.202e-33	139.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YYD2_k127_278852_0	1123278.KB893558_gene3297	2.39e-94	318.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YYD2_k127_278852_3	997346.HMPREF9374_0712	1.352e-61	219.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,27AVW@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosome recycling factor	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YYD2_k127_278852_1	671143.DAMO_0673	1.104e-91	307.0	COG0528@1|root,COG0528@2|Bacteria,2NNRY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
YYD2_k127_278852_4	644966.Tmar_1004	3.782e-60	214.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WD1V@538999|Clostridiales incertae sedis	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YYD2_k127_278852_2	1480694.DC28_00800	1.897e-90	304.0	COG0052@1|root,COG0052@2|Bacteria,2J5GZ@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YYD2_k127_278852_7	1123284.KB899051_gene2000	5.595e-34	135.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,26NRR@186821|Sporolactobacillaceae	91061|Bacilli	J	Ribosomal protein S9/S16	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YYD2_k127_278852_5	1121090.KB894720_gene1913	9.123e-51	185.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,1ZFJA@1386|Bacillus	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YYD2_k127_279821_2	404589.Anae109_1212	8.571e-61	234.0	COG0204@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
YYD2_k127_279821_9	1121104.AQXH01000006_gene2309	2.369e-05	57.0	COG1629@1|root,COG2730@1|root,COG2730@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase,TonB_dep_Rec
YYD2_k127_279821_7	929556.Solca_0196	1.054e-13	82.0	COG1075@1|root,COG1075@2|Bacteria,4NJMQ@976|Bacteroidetes,1IYWC@117747|Sphingobacteriia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
YYD2_k127_279821_5	1223410.KN050846_gene308	4.013e-42	173.0	COG1073@1|root,COG1073@2|Bacteria,4PMNT@976|Bacteroidetes,1HZRQ@117743|Flavobacteriia	976|Bacteroidetes	N	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
YYD2_k127_279821_3	290315.Clim_2082	8.242e-55	199.0	COG2606@1|root,COG2606@2|Bacteria,1FF1M@1090|Chlorobi	1090|Chlorobi	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
YYD2_k127_279821_8	880073.Calab_1226	2.405e-06	60.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	lppL	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_279821_1	1337936.IJ00_19060	1.003e-102	341.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YYD2_k127_279821_4	483219.LILAB_18780	1.358e-53	196.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
YYD2_k127_279821_0	1254432.SCE1572_09510	2.434e-230	722.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
YYD2_k127_279821_6	266117.Rxyl_0724	5.167e-28	120.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
YYD2_k127_2809756_2	545693.BMQ_5109	1.749e-14	75.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,1ZJ2S@1386|Bacillus	91061|Bacilli	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
YYD2_k127_2809756_1	56780.SYN_02215	3.148e-53	207.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
YYD2_k127_2809756_0	1232410.KI421428_gene1054	1.942e-115	391.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_2809756_3	1463820.JOGW01000010_gene947	9.791e-05	50.0	COG2197@1|root,COG2197@2|Bacteria,2GN3A@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	chiR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD2_k127_2813540_2	1379698.RBG1_1C00001G0150	7.738e-44	163.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YYD2_k127_2813540_1	1121428.DESHY_30124___1	1.144e-68	243.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,2601T@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YYD2_k127_2813540_0	1379698.RBG1_1C00001G0153	4.542e-232	726.0	COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YYD2_k127_2813540_3	1379698.RBG1_1C00001G0155	9.921e-34	134.0	COG0355@1|root,COG0355@2|Bacteria,2NPSQ@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	ATP-synt_DE,ATP-synt_DE_N
YYD2_k127_2813540_5	395495.Lcho_1103	8.018e-06	58.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,1KJ02@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
YYD2_k127_2813540_4	215803.DB30_5907	9.198e-27	112.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_281443_4	1123072.AUDH01000007_gene1262	1.906e-45	168.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2JP95@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD2_k127_281443_7	1437824.BN940_04516	2.458e-17	87.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VIV6@28216|Betaproteobacteria,3T1TD@506|Alcaligenaceae	28216|Betaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_281443_2	1125863.JAFN01000001_gene1528	2.3e-113	390.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_281443_3	760568.Desku_2564	2.599e-50	194.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24IAZ@186801|Clostridia,261YP@186807|Peptococcaceae	186801|Clostridia	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
YYD2_k127_281443_6	673860.AciM339_1094	1.334e-31	132.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,3F386@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	HIT domain	hit1	-	2.5.1.3,2.7.7.53,3.6.1.17	ko:K01518,ko:K02503,ko:K19710,ko:K21220	ko00230,ko00240,ko00730,ko01100,map00230,map00240,map00730,map01100	-	R00126,R00184,R00969,R01232,R01618,R02805,R03223,R10712	RC00002,RC00224,RC02753,RC02795,RC03255,RC03397	ko00000,ko00001,ko01000,ko04147	-	-	-	HIT
YYD2_k127_281443_0	330214.NIDE0325	1.131e-143	472.0	COG1236@1|root,COG1236@2|Bacteria,3J0FD@40117|Nitrospirae	40117|Nitrospirae	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
YYD2_k127_281443_1	1519464.HY22_12365	6.151e-123	406.0	COG0381@1|root,COG0381@2|Bacteria,1FDZG@1090|Chlorobi	1090|Chlorobi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YYD2_k127_281443_5	1122179.KB890424_gene3627	4.634e-33	137.0	COG0438@1|root,COG0438@2|Bacteria,4NHPJ@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_281650_3	1267535.KB906767_gene1673	1.952e-87	293.0	2DV1K@1|root,33TIU@2|Bacteria,3Y68F@57723|Acidobacteria,2JKW2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_281650_4	234267.Acid_0708	1.359e-80	271.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
YYD2_k127_281650_2	234267.Acid_0709	3.595e-107	367.0	COG4656@1|root,COG4656@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
YYD2_k127_281650_1	1125863.JAFN01000001_gene2796	3.651e-173	564.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
YYD2_k127_281650_6	1125863.JAFN01000001_gene2795	1.839e-26	124.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
YYD2_k127_281650_0	1125863.JAFN01000001_gene2794	1.994e-199	641.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome b b6 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
YYD2_k127_281650_5	1125863.JAFN01000001_gene2793	8.987e-36	143.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YYD2_k127_281990_2	1201288.M900_1053	1.722e-76	273.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,42TK6@68525|delta/epsilon subdivisions,2MSTK@213481|Bdellovibrionales,2WMDD@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	TIGRFAM phosphonate ABC transporter, inner membrane subunit	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
YYD2_k127_281990_1	1307761.L21SP2_1483	1.575e-81	298.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
YYD2_k127_281990_0	459349.CLOAM1518	1.19e-95	326.0	COG3221@1|root,COG3221@2|Bacteria,2NPZY@2323|unclassified Bacteria	2|Bacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
YYD2_k127_2836824_0	429009.Adeg_1824	0.0	1187.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YYD2_k127_2836824_1	485913.Krac_11103	5.549e-99	336.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD2_k127_2842503_5	1379698.RBG1_1C00001G1725	4.34e-36	147.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
YYD2_k127_2842503_1	1379698.RBG1_1C00001G1724	8.649e-108	382.0	COG0845@1|root,COG0845@2|Bacteria,2NR7K@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YYD2_k127_2842503_6	443143.GM18_2046	3.578e-12	79.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,42UQA@68525|delta/epsilon subdivisions,2WQXF@28221|Deltaproteobacteria,43TDQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD2_k127_2842503_0	1254432.SCE1572_06975	0.0	1169.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YYD2_k127_2842503_3	404589.Anae109_2915	5.557e-59	211.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_2842503_4	1131269.AQVV01000028_gene40	5.114e-48	179.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Nfu_N,NifU
YYD2_k127_2842503_2	886293.Sinac_5331	3.566e-103	340.0	COG0249@1|root,COG0249@2|Bacteria,2IY9B@203682|Planctomycetes	203682|Planctomycetes	L	Mismatch repair ATPase (MutS family)	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
YYD2_k127_2842722_2	631362.Thi970DRAFT_00715	1.669e-48	179.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
YYD2_k127_2842722_1	1120936.KB907226_gene2847	1.596e-63	229.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4EN22@85012|Streptosporangiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD2_k127_2842722_0	443143.GM18_4095	3.854e-95	342.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,43TZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD2_k127_2842722_3	1121904.ARBP01000015_gene200	0.0003952	53.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,47KXU@768503|Cytophagia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
YYD2_k127_2855293_2	1499967.BAYZ01000036_gene2419	4.52e-58	203.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
YYD2_k127_2855293_4	59538.XP_005977183.1	1.471e-23	108.0	COG0474@1|root,KOG0202@2759|Eukaryota,38B7J@33154|Opisthokonta,3BAM2@33208|Metazoa,3CZ7Z@33213|Bilateria,480YI@7711|Chordata,492V5@7742|Vertebrata,3J5GV@40674|Mammalia	33208|Metazoa	P	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YYD2_k127_2855293_1	335543.Sfum_0943	2.339e-61	227.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,43065@68525|delta/epsilon subdivisions,2WV8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD2_k127_2855293_0	631362.Thi970DRAFT_04891	2.719e-111	383.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RNNF@1236|Gammaproteobacteria,1X05T@135613|Chromatiales	135613|Chromatiales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YYD2_k127_2855293_3	1123242.JH636434_gene4709	7.194e-33	131.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD2_k127_286329_0	247490.KSU1_C0701	1.163e-118	404.0	COG0577@1|root,COG0577@2|Bacteria,2IY2P@203682|Planctomycetes	203682|Planctomycetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX,MacB_PCD
YYD2_k127_286329_1	1382306.JNIM01000001_gene783	8.78e-84	286.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_286329_2	1122951.ATUE01000005_gene1555	7.723e-05	49.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,3NJBY@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD2_k127_2884956_4	1379698.RBG1_1C00001G1143	3.705e-27	114.0	COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup_1	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YYD2_k127_2884956_1	1492922.GY26_10715	2.439e-62	228.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1J4HG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YYD2_k127_2884956_3	525904.Tter_1865	1.829e-29	125.0	COG0558@1|root,COG0558@2|Bacteria,2NPRA@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,DUF4833
YYD2_k127_2884956_2	351607.Acel_1971	2.742e-44	177.0	COG0125@1|root,COG0477@1|root,COG0125@2|Bacteria,COG2814@2|Bacteria,2GNTI@201174|Actinobacteria,4ES48@85013|Frankiales	201174|Actinobacteria	EFGP	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
YYD2_k127_2884956_0	335543.Sfum_2531	1.462e-81	289.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MRAV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
YYD2_k127_2891117_0	59374.Fisuc_2848	2.993e-167	541.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria	2|Bacteria	J	methionyl-tRNA aminoacylation	metG	GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.20,6.1.1.6	ko:K01874,ko:K01890,ko:K04566,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03658,R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Anticodon_1,tRNA-synt_1g,tRNA_bind
YYD2_k127_2891117_1	1379698.RBG1_1C00001G0119	3.019e-77	266.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_289839_0	1210884.HG799462_gene8442	8.595e-71	246.0	COG0603@1|root,COG0603@2|Bacteria,2IZ5W@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
YYD2_k127_289839_1	575540.Isop_3456	5.619e-42	157.0	COG0720@1|root,COG0720@2|Bacteria,2J000@203682|Planctomycetes	203682|Planctomycetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
YYD2_k127_289839_2	1128421.JAGA01000002_gene312	1.769e-06	57.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD2_k127_2918478_3	926550.CLDAP_09390	6.942e-52	190.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
YYD2_k127_2918478_0	247490.KSU1_C0085	2.476e-78	270.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YYD2_k127_2918478_2	589865.DaAHT2_1614	2.869e-62	223.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,42R9E@68525|delta/epsilon subdivisions,2WNRJ@28221|Deltaproteobacteria,2MPAU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YYD2_k127_2918478_1	290397.Adeh_3744	2.35e-65	234.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YYD2_k127_2924998_0	935866.JAER01000041_gene3069	2.418e-108	362.0	COG3392@1|root,COG3392@2|Bacteria,2IBCB@201174|Actinobacteria,4DPB3@85009|Propionibacteriales	201174|Actinobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
YYD2_k127_2924998_1	1047013.AQSP01000084_gene763	4.779e-63	231.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YYD2_k127_293135_6	864702.OsccyDRAFT_3403	0.0001328	53.0	COG1912@1|root,COG1912@2|Bacteria,1G1B1@1117|Cyanobacteria,1H78G@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
YYD2_k127_293135_5	404589.Anae109_1180	3.776e-23	103.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YYD2_k127_293135_2	880073.Calab_2472	4.931e-36	158.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
YYD2_k127_293135_4	1382359.JIAL01000001_gene1268	1.576e-33	147.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
YYD2_k127_293135_0	378806.STAUR_8324	1.203e-68	249.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YUUC@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_293135_3	869210.Marky_2237	1.252e-35	142.0	COG2059@1|root,COG2059@2|Bacteria,1WKSK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
YYD2_k127_293135_1	1198232.CYCME_2436	7.887e-54	199.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YYD2_k127_2943929_1	518766.Rmar_2706	5.945e-93	326.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1FIWK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
YYD2_k127_2943929_0	1121430.JMLG01000003_gene624	1.761e-106	370.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD2_k127_2960505_0	448385.sce6976	1.543e-115	394.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
YYD2_k127_2960505_1	1461693.ATO10_00920	1.047e-38	148.0	COG4875@1|root,COG4875@2|Bacteria,1N89Y@1224|Proteobacteria,2UKHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,SnoaL_3
YYD2_k127_2960505_2	639030.JHVA01000001_gene2668	7.462e-25	103.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YYD2_k127_299299_5	865937.Gilli_0819	3.133e-05	51.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	2.6.1.9	ko:K00817,ko:K11777	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	HAD_2,Hydrolase,Hydrolase_like
YYD2_k127_299299_3	383372.Rcas_1616	2.185e-29	130.0	COG2816@1|root,COG2816@2|Bacteria,2GBM2@200795|Chloroflexi,3781X@32061|Chloroflexia	32061|Chloroflexia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD2_k127_299299_0	1201290.M902_1567	3.537e-131	429.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_299299_1	930169.B5T_00970	1.413e-50	188.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1XJB3@135619|Oceanospirillales	135619|Oceanospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
YYD2_k127_299299_4	1198114.AciX9_2150	7.797e-20	92.0	COG2154@1|root,COG2154@2|Bacteria,3Y5UG@57723|Acidobacteria,2JNDN@204432|Acidobacteriia	204432|Acidobacteriia	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YYD2_k127_299299_2	518766.Rmar_0610	3.689e-44	177.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YYD2_k127_2995088_2	330214.NIDE1596	1.667e-50	181.0	COG1225@1|root,COG1225@2|Bacteria,3J13P@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_2995088_0	584708.Apau_0105	9.89e-127	419.0	COG3844@1|root,COG3844@2|Bacteria,3TA91@508458|Synergistetes	508458|Synergistetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
YYD2_k127_2995088_3	1250278.JQNQ01000001_gene1144	2.523e-33	146.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD2_k127_2995088_1	290397.Adeh_0307	4.292e-60	216.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
YYD2_k127_3011640_0	1125863.JAFN01000001_gene2400	2.828e-63	240.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
YYD2_k127_3011640_1	1125863.JAFN01000001_gene4	2.345e-53	210.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42QZK@68525|delta/epsilon subdivisions,2WMZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
YYD2_k127_3040098_2	1089553.Tph_c07150	3.498e-49	182.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YYD2_k127_3040098_0	649638.Trad_2464	4.365e-105	358.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
YYD2_k127_3040098_1	515635.Dtur_1286	1.408e-63	233.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YYD2_k127_3051376_1	479434.Sthe_2195	2.762e-50	198.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,27Z0A@189775|Thermomicrobia	189775|Thermomicrobia	H	Quinolinate phosphoribosyl transferase, N-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YYD2_k127_3051376_0	1191523.MROS_0907	1.689e-167	535.0	COG0556@1|root,COG0556@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YYD2_k127_3055953_3	880073.Calab_1920	4.697e-59	211.0	COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_3055953_2	264732.Moth_2248	2.203e-60	218.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,42FDQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
YYD2_k127_3055953_1	1125863.JAFN01000001_gene2162	3.021e-77	268.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YYD2_k127_3055953_0	1379698.RBG1_1C00001G1627	2.513e-238	761.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YYD2_k127_3055953_4	42256.RradSPS_1974	9.436e-30	128.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YYD2_k127_3055953_5	986075.CathTA2_2663	7.84e-07	53.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YYD2_k127_3066347_1	290397.Adeh_3976	1.767e-14	86.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,42VZ2@68525|delta/epsilon subdivisions,2X8TC@28221|Deltaproteobacteria,2YYPQ@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
YYD2_k127_3066347_0	1123392.AQWL01000002_gene1980	2.61e-137	444.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,1KSIB@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
YYD2_k127_3071190_0	1192034.CAP_4484	2.366e-25	121.0	COG1621@1|root,COG1807@1|root,COG1621@2|Bacteria,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3072777_0	1125863.JAFN01000001_gene2283	7.386e-65	242.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
YYD2_k127_3072777_2	1089544.KB912942_gene2642	0.0002409	54.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4E0TS@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
YYD2_k127_3072777_1	215803.DB30_6216	5.643e-05	54.0	COG0737@1|root,COG0737@2|Bacteria,1ND4P@1224|Proteobacteria,42W6F@68525|delta/epsilon subdivisions,2WRWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	Cytochrome_C554
YYD2_k127_307306_2	1234664.AMRO01000027_gene1268	1.853e-26	118.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1WEKT@129337|Geobacillus	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YYD2_k127_307306_1	635013.TherJR_2563	1.582e-89	299.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,260UI@186807|Peptococcaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YYD2_k127_307306_0	555079.Toce_1766	2.502e-176	561.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YYD2_k127_308062_0	562970.Btus_1051	5.078e-39	153.0	COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,2792M@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD2_k127_308062_1	1210884.HG799463_gene10293	4.352e-23	114.0	COG0535@1|root,COG0535@2|Bacteria,2IWZK@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
YYD2_k127_3090941_0	926560.KE387025_gene4040	3.96e-22	109.0	COG1956@1|root,COG2199@1|root,COG1956@2|Bacteria,COG3706@2|Bacteria,1WITS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD2_k127_3090941_2	390989.JOEG01000019_gene5999	4.993e-06	57.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YYD2_k127_3090941_1	448385.sce6976	6.027e-13	71.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
YYD2_k127_3129282_2	78245.Xaut_0977	0.0002952	53.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,2TVRG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD2_k127_3129282_1	1048834.TC41_2936	1.328e-23	109.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_3129282_0	215803.DB30_3833	1.215e-97	330.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2YX1M@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD2_k127_313103_0	204669.Acid345_3767	4.709e-144	471.0	COG0312@1|root,COG0312@2|Bacteria,3Y6TF@57723|Acidobacteria	57723|Acidobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD2_k127_313103_1	1449126.JQKL01000013_gene3402	5.022e-122	400.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YYD2_k127_314863_4	56110.Oscil6304_1713	2.722e-18	97.0	COG5653@1|root,COG5653@2|Bacteria,1GC7U@1117|Cyanobacteria,1HEMP@1150|Oscillatoriales	1117|Cyanobacteria	M	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
YYD2_k127_314863_3	42256.RradSPS_3078	5.746e-25	110.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
YYD2_k127_314863_2	671143.DAMO_1931	6.491e-44	177.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD2_k127_314863_1	234267.Acid_4152	9.579e-47	193.0	COG0845@1|root,COG0845@2|Bacteria,3Y4YK@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD2_k127_314863_0	269799.Gmet_3127	2.828e-55	199.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,43TI4@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YYD2_k127_3163363_1	1127696.HMPREF9134_01346	1.691e-12	73.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia,22YCQ@171551|Porphyromonadaceae	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_3163363_0	234267.Acid_5088	7.325e-222	698.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD2_k127_3170731_4	1382359.JIAL01000001_gene1199	1.734e-46	184.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
YYD2_k127_3170731_0	357804.Ping_3708	5.354e-115	385.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,2QJ8J@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_3170731_1	1454004.AW11_00065	1.62e-112	377.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_3170731_2	765911.Thivi_0930	1.526e-83	293.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_3170731_3	580332.Slit_2080	2.239e-77	275.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YYD2_k127_3170731_7	1123072.AUDH01000006_gene3251	7.535e-05	56.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,2JSP2@204441|Rhodospirillales	204441|Rhodospirillales	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
YYD2_k127_3170731_5	358681.BBR47_37570	1.769e-45	172.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD2_k127_3170731_6	479434.Sthe_3338	1.143e-27	115.0	COG2329@1|root,COG5485@1|root,COG2329@2|Bacteria,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
YYD2_k127_3241825_0	1379281.AVAG01000001_gene249	1.75e-199	630.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2M8XA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YYD2_k127_3241825_2	1121468.AUBR01000010_gene2431	2.635e-117	403.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
YYD2_k127_3241825_3	195522.BD01_0631	3.663e-30	128.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci	183968|Thermococci	S	Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YYD2_k127_3241825_4	861299.J421_3007	1.108e-24	106.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3241825_1	1191523.MROS_1214	7.343e-170	544.0	2CD20@1|root,2Z7SQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3241825_5	1123023.JIAI01000064_gene9244	0.0007278	51.0	COG0457@1|root,COG0457@2|Bacteria	1123023.JIAI01000064_gene9244|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3247840_1	671143.DAMO_0410	1.013e-155	497.0	COG2060@1|root,COG2060@2|Bacteria,2NP13@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717	KdpA
YYD2_k127_3247840_0	1254432.SCE1572_09215	7.194e-321	996.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2YWXY@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
YYD2_k127_3247840_2	671143.DAMO_0413	2.306e-63	222.0	COG2156@1|root,COG2156@2|Bacteria,2NPIZ@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iEcE24377_1341.EcE24377A_0722,ic_1306.c0781	KdpC
YYD2_k127_3248778_10	880073.Calab_2081	0.0003837	53.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
YYD2_k127_3248778_2	378806.STAUR_6533	5.696e-62	240.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
YYD2_k127_3248778_1	1128421.JAGA01000003_gene3146	3.891e-71	251.0	COG0846@1|root,COG0846@2|Bacteria,2NPJR@2323|unclassified Bacteria	2|Bacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YYD2_k127_3248778_6	330214.NIDE0775	5.669e-11	73.0	COG0558@1|root,COG0558@2|Bacteria,3J183@40117|Nitrospirae	40117|Nitrospirae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YYD2_k127_3248778_0	1379698.RBG1_1C00001G0186	0.0	1105.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.3.13,2.7.9.1	ko:K01006,ko:K22424	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD2_k127_3248778_8	1265502.KB905942_gene2832	7.288e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,1RJ20@1224|Proteobacteria,2WG0T@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_3248778_5	1121930.AQXG01000023_gene1643	4.477e-12	79.0	28KE7@1|root,2ZA0G@2|Bacteria,4P0D4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3248778_4	162425.CADANIAP00002953	4.201e-15	89.0	KOG4155@1|root,KOG4155@2759|Eukaryota,3AG0Y@33154|Opisthokonta,3Q4RG@4751|Fungi,3RN16@4890|Ascomycota,20UKC@147545|Eurotiomycetes,3SE9V@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,PNP_UDP_1,WD40
YYD2_k127_3248778_9	1121930.AQXG01000023_gene1641	2.438e-05	58.0	COG3209@1|root,COG3209@2|Bacteria,4P5ZD@976|Bacteroidetes	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3248778_7	880073.Calab_0039	2.336e-09	70.0	COG0308@1|root,COG0308@2|Bacteria,2NRIZ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Cofac_haem_bdg,NAAA-beta,Peptidase_M1,Phospholip_B
YYD2_k127_3248778_3	459349.CLOAM1790	6.727e-22	109.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
YYD2_k127_3251442_1	1385514.N782_10790	2.025e-35	145.0	COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,2Y9BK@289201|Pontibacillus	91061|Bacilli	S	Major pilin protein fimA	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
YYD2_k127_3251442_2	861299.J421_2050	6.746e-30	124.0	COG3695@1|root,COG3695@2|Bacteria	2|Bacteria	L	enzyme binding	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,YjbR
YYD2_k127_3251442_0	264462.Bd2784	5.08e-321	1000.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2MTH2@213481|Bdellovibrionales,2WIIV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	aconitate hydratase	aco	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD2_k127_3255365_0	530564.Psta_2426	6.145e-79	273.0	COG0564@1|root,COG0564@2|Bacteria,2J01R@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD2_k127_3255365_1	1122603.ATVI01000001_gene1875	3.811e-39	152.0	COG2885@1|root,COG2885@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the ompA family	mopB	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
YYD2_k127_325603_0	667014.Thein_1214	7.627e-132	436.0	COG0151@1|root,COG0151@2|Bacteria,2GGTX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
YYD2_k127_325603_1	269799.Gmet_2903	4.161e-45	173.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria,43UKG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YYD2_k127_3256162_6	868595.Desca_2117	3.892e-35	144.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,260JY@186807|Peptococcaceae	186801|Clostridia	CI	Acetyl-CoA carboxylase, biotin carboxyl carrier protein	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
YYD2_k127_3256162_1	1121920.AUAU01000018_gene1781	2.298e-189	602.0	COG0439@1|root,COG0439@2|Bacteria,3Y2QZ@57723|Acidobacteria	57723|Acidobacteria	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD2_k127_3256162_0	204669.Acid345_1392	1.112e-248	779.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
YYD2_k127_3256162_2	204669.Acid345_1391	7.159e-171	544.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD2_k127_3256162_3	204669.Acid345_1390	2.77e-143	464.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YYD2_k127_3256162_5	330214.NIDE0778	1.041e-79	287.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
YYD2_k127_3256162_4	1499967.BAYZ01000027_gene1786	2.878e-128	459.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_3256162_7	1499967.BAYZ01000075_gene2072	9.58e-28	120.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
YYD2_k127_3256345_0	945713.IALB_2399	9.236e-36	150.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	DUF2723,PMT_2
YYD2_k127_3256345_1	269799.Gmet_0042	3.172e-28	126.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
YYD2_k127_3264782_2	1150474.JQJI01000010_gene1073	3.989e-14	79.0	COG2076@1|root,COG2076@2|Bacteria,2GDJW@200918|Thermotogae	200918|Thermotogae	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Multi_Drug_Res
YYD2_k127_3264782_0	379066.GAU_2901	2.541e-52	206.0	COG0125@1|root,COG0125@2|Bacteria,1ZUCV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
YYD2_k127_3264782_1	1227739.Hsw_1020	4.639e-16	92.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,47Q56@768503|Cytophagia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
YYD2_k127_3265534_2	903818.KI912268_gene2323	8.526e-78	276.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria	57723|Acidobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
YYD2_k127_3265534_3	926550.CLDAP_20490	9.834e-78	278.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
YYD2_k127_3265534_1	1278073.MYSTI_06635	1.468e-148	485.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_3265534_0	497964.CfE428DRAFT_2129	6.223e-294	917.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD2_k127_3274074_6	935567.JAES01000020_gene563	6.843e-05	55.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1X5KW@135614|Xanthomonadales	135614|Xanthomonadales	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_16
YYD2_k127_3274074_0	266117.Rxyl_2763	9.203e-165	537.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YYD2_k127_3274074_3	1121405.dsmv_3093	5.683e-72	265.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria,2MMYR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YYD2_k127_3274074_4	671143.DAMO_2120	6.448e-54	218.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
YYD2_k127_3274074_2	379066.GAU_2447	1.39e-72	262.0	COG0534@1|root,COG0534@2|Bacteria,1ZTFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
YYD2_k127_3274074_1	243231.GSU1796	1.043e-78	273.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,43SCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
YYD2_k127_3279010_3	1173028.ANKO01000106_gene307	5.219e-11	76.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_2,TPR_8
YYD2_k127_3279010_1	880073.Calab_3781	1.068e-114	379.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YYD2_k127_3279010_0	880073.Calab_3781	2.215e-137	445.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YYD2_k127_3279010_2	306281.AJLK01000072_gene645	1.577e-54	197.0	COG1764@1|root,COG1764@2|Bacteria,1G767@1117|Cyanobacteria,1JKB8@1189|Stigonemataceae	1117|Cyanobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
YYD2_k127_3281463_0	1267535.KB906767_gene3542	4.043e-169	536.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YYD2_k127_3281463_2	240015.ACP_3109	5.046e-17	93.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
YYD2_k127_3281463_4	1340493.JNIF01000003_gene1706	0.0005216	53.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
YYD2_k127_3281463_1	1047013.AQSP01000036_gene1385	4.601e-59	221.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
YYD2_k127_3282646_5	865937.Gilli_0729	4.098e-25	109.0	COG3011@1|root,COG3011@2|Bacteria,4NPGN@976|Bacteroidetes,1I2KY@117743|Flavobacteriia,2P7K2@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
YYD2_k127_3282646_2	3988.XP_002536412.1	3.06e-96	321.0	COG0450@1|root,KOG0854@2759|Eukaryota,37SP5@33090|Viridiplantae,3GAU6@35493|Streptophyta,4JMYM@91835|fabids	35493|Streptophyta	O	1-Cys peroxiredoxin	-	-	1.11.1.15,1.11.1.7	ko:K11188	ko00940,ko01100,ko01110,map00940,map01100,map01110	-	R00602,R02596,R03919,R04007,R07443	RC00034	ko00000,ko00001,ko01000	-	-	-	1-cysPrx_C,AhpC-TSA
YYD2_k127_3282646_1	472759.Nhal_2910	2.993e-172	552.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,1WXIJ@135613|Chromatiales	135613|Chromatiales	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
YYD2_k127_3282646_3	266117.Rxyl_0746	7.593e-89	322.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_3282646_6	1183438.GKIL_0677	7.745e-25	111.0	COG1310@1|root,COG1310@2|Bacteria,1G7SZ@1117|Cyanobacteria	1117|Cyanobacteria	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
YYD2_k127_3282646_0	1303518.CCALI_00532	1.592e-174	561.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
YYD2_k127_3282646_11	1480694.DC28_01735	1.072e-05	57.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
YYD2_k127_3282646_12	926561.KB900617_gene1658	7.762e-05	55.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,25413@186801|Clostridia,3WC1R@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM TonB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
YYD2_k127_3282646_9	62928.azo0419	5.469e-09	64.0	COG0848@1|root,COG0848@2|Bacteria,1NFDF@1224|Proteobacteria,2VWMV@28216|Betaproteobacteria,2KZ18@206389|Rhodocyclales	206389|Rhodocyclales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
YYD2_k127_3282646_10	1094553.MCS_01232	9.668e-06	53.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,48TZE@772|Bartonellaceae	28211|Alphaproteobacteria	U	Biopolymer transport protein ExbD/TolR	exbD	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YYD2_k127_3282646_8	637389.Acaty_c0347	1.592e-20	105.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,2NCJP@225057|Acidithiobacillales	225057|Acidithiobacillales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YYD2_k127_3282646_14	1122197.ATWI01000009_gene1382	0.000829	53.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,YfiO
YYD2_k127_3282646_13	907348.TresaDRAFT_1714	0.0001029	54.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
YYD2_k127_3282646_4	1379698.RBG1_1C00001G1334	5.202e-29	131.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
YYD2_k127_3282646_7	1297865.APJD01000003_gene6130	1.817e-24	119.0	COG1572@1|root,COG2755@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1572@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JWUW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HemolysinCabind
YYD2_k127_3284957_0	1144275.COCOR_07662	2.866e-295	944.0	COG0308@1|root,COG1668@1|root,COG0308@2|Bacteria,COG1668@2|Bacteria,1PTWJ@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1
YYD2_k127_3284957_1	1144275.COCOR_07663	4.207e-123	404.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria	1224|Proteobacteria	V	(ABC) transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_3284957_2	545276.KB898730_gene1472	7.145e-35	145.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,1SMYA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3284957_3	190650.CC_3417	2.691e-16	80.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
YYD2_k127_3288898_2	1123508.JH636441_gene3757	5.953e-12	66.0	COG4877@1|root,COG4877@2|Bacteria,2J4M8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3288898_0	1123376.AUIU01000012_gene1444	1.519e-143	466.0	COG0156@1|root,COG0156@2|Bacteria,3J0XU@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_3288898_1	1267535.KB906767_gene1674	1.23e-61	241.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
YYD2_k127_3288898_3	1120960.ATXG01000004_gene1655	1.985e-10	68.0	COG0524@1|root,COG0524@2|Bacteria,2IKD4@201174|Actinobacteria	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.218	ko:K10710	-	-	R08124	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
YYD2_k127_3293381_0	1047013.AQSP01000077_gene2274	3.301e-148	483.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
YYD2_k127_3293381_3	1047013.AQSP01000093_gene13	4.081e-28	122.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
YYD2_k127_3293381_2	1047013.AQSP01000093_gene14	2.134e-36	152.0	COG2920@1|root,COG2920@2|Bacteria,2NQ6I@2323|unclassified Bacteria	2|Bacteria	P	DsrC like protein	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
YYD2_k127_3293381_1	1173022.Cri9333_2806	3.397e-51	191.0	COG2340@1|root,COG2340@2|Bacteria,1G68A@1117|Cyanobacteria,1HBHS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
YYD2_k127_3293381_4	459349.CLOAM1307	3.941e-06	55.0	COG1361@1|root,COG1361@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,FlgD_ig,SdrD_B
YYD2_k127_3304931_0	1121904.ARBP01000014_gene142	4.098e-54	198.0	arCOG07533@1|root,2ZF5I@2|Bacteria,4NS85@976|Bacteroidetes,47X6K@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
YYD2_k127_3304931_4	378806.STAUR_6820	2.734e-18	97.0	2CDDP@1|root,33XZD@2|Bacteria,1NVRR@1224|Proteobacteria,4380H@68525|delta/epsilon subdivisions,2X3AJ@28221|Deltaproteobacteria,2YV52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3304931_3	1128912.GMES_4405	8.199e-19	100.0	COG3540@1|root,COG3540@2|Bacteria,1NRFH@1224|Proteobacteria,1SJKC@1236|Gammaproteobacteria,469GY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3304931_5	880073.Calab_0544	1.632e-07	64.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-binding_MopE,FlgD_ig
YYD2_k127_3304931_1	1183438.GKIL_2106	6.969e-40	168.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
YYD2_k127_3304931_2	1122132.AQYH01000010_gene4009	8.476e-25	116.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YYD2_k127_3310703_2	913325.N799_06400	4.971e-53	194.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1X37F@135614|Xanthomonadales	135614|Xanthomonadales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YYD2_k127_3310703_0	204669.Acid345_4185	5.77e-203	641.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria,2JM1F@204432|Acidobacteriia	204432|Acidobacteriia	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
YYD2_k127_3310703_4	298654.FraEuI1c_5769	4.379e-28	120.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria	201174|Actinobacteria	C	NADP transhydrogenase	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
YYD2_k127_3310703_1	330214.NIDE3615	7.276e-133	438.0	COG2081@1|root,COG2081@2|Bacteria,3J12U@40117|Nitrospirae	40117|Nitrospirae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
YYD2_k127_3310703_3	419610.Mext_4281	2.865e-32	146.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,1JSKK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YYD2_k127_3310703_5	1192034.CAP_3155	1.214e-05	56.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
YYD2_k127_3339538_1	502025.Hoch_0385	1.039e-92	311.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	-	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
YYD2_k127_3339538_0	314285.KT71_17271	1.427e-143	478.0	COG1404@1|root,COG1404@2|Bacteria,1PE2Y@1224|Proteobacteria,1SQ8B@1236|Gammaproteobacteria,1JBCF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_3345916_0	1265313.HRUBRA_02304	4.165e-27	127.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria	1224|Proteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3356342_2	797299.HALLA_12770	0.0004317	43.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota,23TIK@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD2_k127_3356342_1	1089550.ATTH01000001_gene548	5.035e-34	146.0	2DG3I@1|root,2ZUAR@2|Bacteria	1089550.ATTH01000001_gene548|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3356342_0	886293.Sinac_6090	2.987e-46	169.0	COG0693@1|root,COG0693@2|Bacteria,2IYYE@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YYD2_k127_3367534_5	862908.BMS_2992	1.418e-83	301.0	COG0451@1|root,COG0451@2|Bacteria,1NEDD@1224|Proteobacteria,42QH7@68525|delta/epsilon subdivisions,2WIME@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3367534_15	102129.Lepto7375DRAFT_2341	1.088e-06	61.0	COG0392@1|root,COG0392@2|Bacteria,1G41A@1117|Cyanobacteria,1HD8Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD2_k127_3367534_10	1191523.MROS_0338	8.402e-26	114.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YYD2_k127_3367534_4	1379698.RBG1_1C00001G0735	3.217e-89	303.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
YYD2_k127_3367534_1	1379698.RBG1_1C00001G0736	1.913e-220	705.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
YYD2_k127_3367534_6	869210.Marky_1897	5.076e-57	216.0	COG0719@1|root,COG0719@2|Bacteria,1WJ1E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	TIGRFAM FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
YYD2_k127_3367534_12	886293.Sinac_5289	6.505e-25	111.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
YYD2_k127_3367534_2	266117.Rxyl_0166	3.713e-159	518.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
YYD2_k127_3367534_7	1379698.RBG1_1C00001G0740	4.161e-35	143.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YYD2_k127_3367534_13	525904.Tter_1833	1.12e-21	104.0	COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria	2|Bacteria	S	Pfam:DUF59	yitW	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
YYD2_k127_3367534_11	596151.DesfrDRAFT_0689	1.567e-25	119.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,42Z10@68525|delta/epsilon subdivisions,2WU0N@28221|Deltaproteobacteria,2M9PY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
YYD2_k127_3367534_9	1242864.D187_002024	5.952e-34	149.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MASE1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD2_k127_3367534_3	321332.CYB_1511	3.385e-146	482.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,1GYWY@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
YYD2_k127_3367534_14	443144.GM21_1590	3.818e-18	99.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43U0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YYD2_k127_3367534_0	1267535.KB906767_gene2350	2.29e-302	937.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YYD2_k127_3367534_16	1296990.H845_3202	0.0004768	49.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2JPB2@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YYD2_k127_3370262_0	768671.ThimaDRAFT_1344	3.521e-22	107.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,1X0DY@135613|Chromatiales	135613|Chromatiales	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
YYD2_k127_3370262_1	1128421.JAGA01000002_gene587	7.363e-08	64.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD2_k127_3383603_1	869210.Marky_2223	1.281e-16	85.0	COG4911@1|root,COG4911@2|Bacteria,1WJWB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
YYD2_k127_3383603_0	321327.CYA_2514	9.474e-124	409.0	COG1473@1|root,COG1473@2|Bacteria,1G01G@1117|Cyanobacteria,1GYJQ@1129|Synechococcus	1117|Cyanobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	ama	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_3383603_2	545276.KB898730_gene1483	2.673e-12	76.0	COG2062@1|root,COG2062@2|Bacteria,1NH0V@1224|Proteobacteria,1SJ8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
YYD2_k127_3427004_5	85643.Tmz1t_2951	7.909e-64	225.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
YYD2_k127_3427004_1	316067.Geob_0097	1.475e-112	375.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_3427004_2	406817.XNC1_2156	2.602e-87	318.0	COG1022@1|root,COG3321@1|root,COG1022@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
YYD2_k127_3427004_4	1121405.dsmv_2843	4.387e-68	248.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	TIGRFAM CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
YYD2_k127_3427004_0	1125863.JAFN01000001_gene2400	7.292e-166	532.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
YYD2_k127_3427004_6	1121405.dsmv_2843	5.481e-36	154.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	TIGRFAM CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
YYD2_k127_3427004_3	1125863.JAFN01000001_gene2400	8.719e-82	283.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
YYD2_k127_347478_4	1250232.JQNJ01000001_gene3799	3.624e-15	85.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
YYD2_k127_347478_0	880073.Calab_2268	9.175e-199	639.0	COG0006@1|root,COG0006@2|Bacteria,2NNZX@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9	ko:K01262,ko:K02027	-	M00207	-	-	ko00000,ko00002,ko01000,ko01002,ko02000	3.A.1.1	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
YYD2_k127_347478_6	525904.Tter_1998	0.0008308	50.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CW_binding_1,Cellulase,Collagen_bind_2,DUF4038,DUF5060
YYD2_k127_347478_1	1144275.COCOR_00586	1.015e-133	440.0	COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,42PE0@68525|delta/epsilon subdivisions,2WITD@28221|Deltaproteobacteria,2YUZH@29|Myxococcales	28221|Deltaproteobacteria	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
YYD2_k127_347478_3	204669.Acid345_2640	3.2e-45	182.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_2,Abhydrolase_4,Esterase
YYD2_k127_347478_2	66692.ABC0375	2.443e-110	386.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli,1ZC3P@1386|Bacillus	91061|Bacilli	IQ	Class II Aldolase and Adducin N-terminal domain	yuxG	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
YYD2_k127_347478_5	358681.BBR47_07420	4.447e-06	55.0	COG1266@1|root,COG1266@2|Bacteria,1V8M6@1239|Firmicutes,4HJJJ@91061|Bacilli,26XPV@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD2_k127_3489449_0	886293.Sinac_7050	1.839e-30	140.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IY73@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16
YYD2_k127_3493278_3	1234595.C725_0313	1.574e-05	53.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,4BQB6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YYD2_k127_3493278_2	1122180.Lokhon_00113	2.638e-15	81.0	COG0463@1|root,COG0463@2|Bacteria,1REDH@1224|Proteobacteria,2UEN2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_3493278_0	667014.Thein_2151	1.438e-70	257.0	COG0463@1|root,COG0463@2|Bacteria,2GHE8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_3493278_1	102129.Lepto7375DRAFT_5494	9.873e-42	160.0	COG0500@1|root,COG2226@2|Bacteria,1G3CH@1117|Cyanobacteria,1HAB6@1150|Oscillatoriales	1117|Cyanobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD2_k127_3493383_1	204669.Acid345_3938	2.306e-28	131.0	COG1208@1|root,COG1208@2|Bacteria,3Y4HJ@57723|Acidobacteria	57723|Acidobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
YYD2_k127_3493383_0	706587.Desti_1114	1.124e-108	364.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MRDD@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
YYD2_k127_3493412_2	338969.Rfer_3145	4.981e-19	90.0	COG0599@1|root,COG0599@2|Bacteria,1P85X@1224|Proteobacteria,2W5YK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YYD2_k127_3493412_0	338969.Rfer_3144	7.444e-66	236.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_3493412_1	1538295.JY96_18405	3.569e-57	202.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,1KN9K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
YYD2_k127_3497471_5	1125863.JAFN01000001_gene103	1.72e-24	110.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
YYD2_k127_3497471_4	443143.GM18_0784	2.898e-28	125.0	COG2050@1|root,COG2050@2|Bacteria,1R0AE@1224|Proteobacteria,43CSS@68525|delta/epsilon subdivisions,2WU2I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
YYD2_k127_3497471_6	1131814.JAFO01000001_gene4702	3.088e-09	64.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
YYD2_k127_3497471_2	1191523.MROS_1563	5.861e-51	194.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7,Multi-haem_cyto
YYD2_k127_3497471_1	1379698.RBG1_1C00001G0778	1.692e-135	447.0	COG3005@1|root,COG3005@2|Bacteria,2NQ9M@2323|unclassified Bacteria	2|Bacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
YYD2_k127_3497471_0	880073.Calab_1599	3.885e-173	566.0	COG2864@1|root,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YYD2_k127_3497471_3	1379698.RBG1_1C00001G0777	9.72e-38	150.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
YYD2_k127_3497747_2	9913.ENSBTAP00000003805	6.802e-41	156.0	COG4826@1|root,KOG2392@2759|Eukaryota,38VR6@33154|Opisthokonta,3BBFJ@33208|Metazoa,3CV81@33213|Bilateria,482SZ@7711|Chordata,496G1@7742|Vertebrata,3JCVT@40674|Mammalia,4J9MM@91561|Cetartiodactyla	33208|Metazoa	V	Belongs to the serpin family	SERPINB3	GO:0000323,GO:0001618,GO:0001775,GO:0001932,GO:0001933,GO:0002020,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0004869,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0006469,GO:0006810,GO:0006887,GO:0006955,GO:0007154,GO:0007267,GO:0008150,GO:0008284,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010466,GO:0010563,GO:0010604,GO:0010605,GO:0010646,GO:0010648,GO:0010717,GO:0010718,GO:0010950,GO:0010951,GO:0010952,GO:0012505,GO:0016032,GO:0016192,GO:0019058,GO:0019220,GO:0019222,GO:0019899,GO:0023051,GO:0023052,GO:0023057,GO:0030141,GO:0030162,GO:0030234,GO:0030260,GO:0030334,GO:0030335,GO:0030414,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032270,GO:0032872,GO:0032873,GO:0032879,GO:0032940,GO:0033673,GO:0034774,GO:0035425,GO:0035578,GO:0036230,GO:0038001,GO:0040012,GO:0040017,GO:0042119,GO:0042127,GO:0042325,GO:0042326,GO:0042582,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043506,GO:0043508,GO:0043549,GO:0044092,GO:0044093,GO:0044403,GO:0044409,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045595,GO:0045597,GO:0045859,GO:0045861,GO:0045862,GO:0045936,GO:0046328,GO:0046329,GO:0046718,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051272,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0070302,GO:0070303,GO:0071900,GO:0071901,GO:0080090,GO:0080134,GO:0080135,GO:0097708,GO:0098772,GO:0099503,GO:0104005,GO:1902531,GO:1902532,GO:2000026,GO:2000145,GO:2000147	-	ko:K13963,ko:K13966	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YYD2_k127_3497747_1	1198452.Jab_1c23560	2.546e-53	195.0	COG4430@1|root,COG4430@2|Bacteria,1RG2R@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
YYD2_k127_3497747_0	1192034.CAP_4790	4.301e-146	475.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2WJXZ@28221|Deltaproteobacteria,2YUTQ@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
YYD2_k127_3497747_3	1121920.AUAU01000013_gene1721	6.798e-14	72.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_3531725_9	404589.Anae109_0759	1.696e-15	78.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YYD2_k127_3531725_3	1449346.JQMO01000003_gene4225	6.46e-138	449.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,2M0IA@2063|Kitasatospora	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_3531725_1	247490.KSU1_D0121	2.314e-178	568.0	COG0538@1|root,COG0538@2|Bacteria,2J51C@203682|Planctomycetes	203682|Planctomycetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
YYD2_k127_3531725_5	1047013.AQSP01000062_gene1209	1.804e-52	209.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	XK27_02215	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5
YYD2_k127_3531725_8	1294273.roselon_00827	3.905e-42	170.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG1956 GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
YYD2_k127_3531725_6	292459.STH1524	1.967e-50	194.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YYD2_k127_3531725_2	1379698.RBG1_1C00001G0513	6.202e-147	479.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YYD2_k127_3531725_4	289376.THEYE_A0567	3.769e-129	423.0	COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_3531725_7	935840.JAEQ01000007_gene3855	4.964e-48	177.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,43IDN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630	-	R00653	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	Pep_deformylase
YYD2_k127_3531725_0	204669.Acid345_3065	1.687e-193	619.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
YYD2_k127_3536148_0	653733.Selin_0886	2.379e-160	514.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
YYD2_k127_3536148_1	716928.AJQT01000068_gene3402	3.491e-34	135.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2UPFY@28211|Alphaproteobacteria,4B9SR@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	oxidoreductase	nuoE2	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YYD2_k127_3538290_0	313590.MED134_01460	5.857e-130	429.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia,37EAT@326319|Dokdonia	976|Bacteroidetes	E	Aminotransferase class-V	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_3538290_1	880073.Calab_2775	3.869e-25	112.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.11.1,4.6.1.1	ko:K01768,ko:K12132	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	DUF3467
YYD2_k127_3539866_1	1123368.AUIS01000028_gene1311	5.214e-91	316.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,2NCSC@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD2_k127_3539866_0	525897.Dbac_2863	1.093e-104	369.0	COG1042@1|root,COG1042@2|Bacteria,1NU6B@1224|Proteobacteria,42NAU@68525|delta/epsilon subdivisions,2WJHX@28221|Deltaproteobacteria,2M8HI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YYD2_k127_3539866_2	1185876.BN8_00183	4.952e-72	260.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
YYD2_k127_3545461_0	1379698.RBG1_1C00001G1355	3.478e-40	155.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YYD2_k127_3545461_1	483219.LILAB_31135	0.0001232	53.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
YYD2_k127_3545462_3	272134.KB731324_gene5171	6.425e-05	55.0	COG0510@1|root,COG0510@2|Bacteria,1G023@1117|Cyanobacteria,1HEZ0@1150|Oscillatoriales	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD2_k127_3545462_0	234267.Acid_4030	3.717e-120	418.0	COG1132@1|root,COG1132@2|Bacteria,3Y6PT@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD2_k127_3545462_2	380394.Lferr_0766	2.362e-71	276.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,2NDHR@225057|Acidithiobacillales	225057|Acidithiobacillales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_3545462_1	1033736.CAHK01000033_gene1090	1.29e-89	335.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4F91M@85019|Brevibacteriaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_3545519_9	1317122.ATO12_12685	2.48e-08	67.0	COG2730@1|root,COG3250@1|root,COG4733@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,COG4733@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2YJTE@290174|Aquimarina	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,F5_F8_type_C,fn3
YYD2_k127_3545519_2	861299.J421_2495	3.527e-52	198.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
YYD2_k127_3545519_4	1499967.BAYZ01000121_gene3405	3.155e-27	124.0	COG1596@1|root,COG1596@2|Bacteria,2NPNM@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide export protein	-	-	-	ko:K01991,ko:K20988	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YYD2_k127_3545519_6	883.DvMF_0688	5.133e-12	79.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42PYQ@68525|delta/epsilon subdivisions,2WKRC@28221|Deltaproteobacteria,2MADY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
YYD2_k127_3545519_5	595460.RRSWK_05514	3.21e-23	109.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2IZZC@203682|Planctomycetes	203682|Planctomycetes	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31
YYD2_k127_3545519_1	1121439.dsat_1282	2.071e-71	255.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,439Z2@68525|delta/epsilon subdivisions,2X1YW@28221|Deltaproteobacteria,2M834@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_3545519_3	357808.RoseRS_3322	1.83e-46	194.0	COG1413@1|root,COG2909@1|root,COG3947@1|root,COG1413@2|Bacteria,COG2909@2|Bacteria,COG3947@2|Bacteria,2G6RU@200795|Chloroflexi,375JR@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HEAT_2,Trans_reg_C
YYD2_k127_3545519_8	518766.Rmar_0260	7.604e-10	72.0	COG4447@1|root,COG4447@2|Bacteria,4P02B@976|Bacteroidetes,1FIYU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
YYD2_k127_3545519_7	1379698.RBG1_1C00001G1377	6.138e-10	72.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
YYD2_k127_3545519_11	756067.MicvaDRAFT_0991	7.058e-05	50.0	2DKXX@1|root,30TW4@2|Bacteria,1G65F@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3545519_10	1123242.JH636435_gene1594	6.808e-07	53.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YYD2_k127_3545519_0	1123242.JH636435_gene1594	4.093e-144	466.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YYD2_k127_3550691_3	331869.BAL199_03269	1.494e-14	75.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,4BPPR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YYD2_k127_3550691_2	1382359.JIAL01000001_gene1420	3.211e-70	245.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria,2JJ36@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD2_k127_3550691_1	1125863.JAFN01000001_gene2454	1.455e-90	309.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
YYD2_k127_3550691_0	1120972.AUMH01000004_gene1385	4.9e-107	353.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,279A5@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK5	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD2_k127_3558153_0	706587.Desti_4883	2.933e-90	310.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
YYD2_k127_3558153_2	459495.SPLC1_S500880	5.621e-71	255.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria,1H9KV@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
YYD2_k127_3558153_4	945713.IALB_2812	2.232e-28	122.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YYD2_k127_3558153_5	1449343.JQLQ01000002_gene79	1.242e-26	113.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HXJS@91061|Bacilli,27HYK@186828|Carnobacteriaceae	91061|Bacilli	J	Translation initiation factor 1A / IF-1	-	-	-	-	-	-	-	-	-	-	-	-	eIF-1a
YYD2_k127_3558153_3	530564.Psta_1506	5.071e-29	119.0	COG0724@1|root,COG0724@2|Bacteria,2J0SR@203682|Planctomycetes	203682|Planctomycetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD2_k127_3558153_1	1125863.JAFN01000001_gene2041	3.499e-79	284.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YYD2_k127_3558153_7	1242864.D187_009699	1.946e-07	61.0	2BRRN@1|root,32KRG@2|Bacteria,1Q9QC@1224|Proteobacteria,434IP@68525|delta/epsilon subdivisions,2WYVX@28221|Deltaproteobacteria,2Z0RV@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
YYD2_k127_3558153_6	204669.Acid345_4187	2.309e-23	104.0	COG3288@1|root,COG3288@2|Bacteria,3Y2S0@57723|Acidobacteria,2JM52@204432|Acidobacteriia	204432|Acidobacteriia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
YYD2_k127_3568962_0	521045.Kole_0173	1.015e-280	887.0	COG0495@1|root,COG0495@2|Bacteria,2GC3Z@200918|Thermotogae	200918|Thermotogae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YYD2_k127_3570325_4	526226.Gbro_2102	0.0005817	44.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4GBDZ@85026|Gordoniaceae	201174|Actinobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD2_k127_3570325_1	1379698.RBG1_1C00001G0961	1.114e-240	771.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
YYD2_k127_3570325_0	1379698.RBG1_1C00001G1656	0.0	1153.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YYD2_k127_3570325_2	459349.CLOAM1266	2.381e-34	138.0	COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	sec59	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YYD2_k127_3570325_3	111781.Lepto7376_2259	3.052e-06	51.0	COG0457@1|root,COG0741@1|root,COG1729@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,COG1729@2|Bacteria,1G1HC@1117|Cyanobacteria,1H76P@1150|Oscillatoriales	1117|Cyanobacteria	M	COGs COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
YYD2_k127_3574708_0	717231.Flexsi_0576	1.039e-12	68.0	COG2204@1|root,COG2204@2|Bacteria,2GF35@200930|Deferribacteres	200930|Deferribacteres	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_3576136_0	479434.Sthe_2189	1.072e-22	108.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_358055_1	1125863.JAFN01000001_gene514	3.371e-98	328.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WJNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
YYD2_k127_358055_4	1121468.AUBR01000030_gene1250	1.576e-53	205.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC4@186801|Clostridia,42IAE@68295|Thermoanaerobacterales	186801|Clostridia	E	Amino-transferase class IV	ilvE2	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD2_k127_358055_6	211586.SO_0409	7.346e-16	90.0	COG0526@1|root,COG0526@2|Bacteria,1NAHI@1224|Proteobacteria,1SCND@1236|Gammaproteobacteria,2QB1H@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
YYD2_k127_358055_7	1089455.MOPEL_029_01620	5.83e-07	61.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria,4F81J@85018|Dermatophilaceae	201174|Actinobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
YYD2_k127_358055_5	234267.Acid_3653	1.19e-22	106.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_2
YYD2_k127_358055_2	404589.Anae109_0052	2.416e-86	292.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YYD2_k127_358055_3	247490.KSU1_C0198	3.099e-64	232.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
YYD2_k127_358055_0	379066.GAU_2872	6.385e-174	565.0	COG0841@1|root,COG0841@2|Bacteria,1ZUFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD2_k127_3581021_0	1121413.JMKT01000001_gene1689	8.254e-125	411.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,42NK8@68525|delta/epsilon subdivisions,2WIM0@28221|Deltaproteobacteria,2M8SV@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
YYD2_k127_3581021_1	644282.Deba_2013	1.501e-55	214.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
YYD2_k127_3586762_0	1089550.ATTH01000001_gene1831	1.947e-118	405.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
YYD2_k127_3586762_3	880073.Calab_2214	5.565e-11	77.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
YYD2_k127_3586762_2	1089548.KI783301_gene205	3.653e-21	110.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
YYD2_k127_3586762_1	391625.PPSIR1_11110	3.141e-69	246.0	COG2988@1|root,COG2988@2|Bacteria	2|Bacteria	E	succinylglutamate desuccinylase activity	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
YYD2_k127_3587669_2	1123073.KB899241_gene2459	2.852e-05	48.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,1X31W@135614|Xanthomonadales	135614|Xanthomonadales	J	pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
YYD2_k127_3587669_1	62928.azo0386	2.531e-13	83.0	COG1807@1|root,COG1807@2|Bacteria,1PVFF@1224|Proteobacteria,2WB9Q@28216|Betaproteobacteria,2KZFX@206389|Rhodocyclales	206389|Rhodocyclales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_3587669_3	234267.Acid_4430	6.84e-05	56.0	COG0457@1|root,COG0726@1|root,COG4249@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria,COG4249@2|Bacteria,3Y77C@57723|Acidobacteria	57723|Acidobacteria	G	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Polysacc_deac_1,TPR_2,WD40
YYD2_k127_3587669_0	1121441.AUCX01000017_gene2004	3.198e-237	758.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
YYD2_k127_3608953_0	1379698.RBG1_1C00001G1860	4.128e-138	447.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YYD2_k127_3612819_0	290397.Adeh_1107	6.311e-147	480.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YYD2_k127_3612819_1	1340493.JNIF01000003_gene1428	3.81e-08	61.0	COG4980@1|root,COG4980@2|Bacteria,3Y5IA@57723|Acidobacteria	57723|Acidobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
YYD2_k127_3613292_1	886293.Sinac_6872	3.003e-15	78.0	COG3330@1|root,COG3330@2|Bacteria,2IWVT@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
YYD2_k127_3613292_0	1121472.AQWN01000002_gene2293	5.383e-190	610.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
YYD2_k127_3620044_7	1120973.AQXL01000121_gene88	5.576e-09	63.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,279BF@186823|Alicyclobacillaceae	91061|Bacilli	D	Segregation and condensation protein ScpA	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YYD2_k127_3620044_5	247490.KSU1_D0660	3.844e-41	161.0	COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YYD2_k127_3620044_3	429009.Adeg_1292	2.564e-57	207.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD2_k127_3620044_4	1218076.BAYB01000015_gene3212	7.408e-53	201.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,1JZU8@119060|Burkholderiaceae	28216|Betaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,4.2.1.91,5.4.99.5	ko:K01713,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
YYD2_k127_3620044_1	264732.Moth_1332	4.819e-98	336.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,42ER2@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
YYD2_k127_3620044_2	1410617.JHXH01000008_gene2147	1.854e-57	217.0	COG0204@1|root,COG0283@1|root,COG0204@2|Bacteria,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
YYD2_k127_3620044_0	1379698.RBG1_1C00001G1225	1.022e-212	676.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
YYD2_k127_3620044_6	1379698.RBG1_1C00001G1136	2.809e-19	100.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	ciaB	-	-	ko:K07502,ko:K08309,ko:K19804,ko:K21572	-	-	-	-	ko00000,ko01000,ko01011,ko02000	8.A.46.1,8.A.46.3	GH23	-	SusD-like_3,SusD_RagB,TPR_16,TPR_6,TPR_8
YYD2_k127_3635761_0	485915.Dret_1838	3.397e-51	191.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MA3S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
YYD2_k127_3635761_1	459349.CLOAM1225	2.716e-14	84.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3654616_1	330214.NIDE0407	1.12e-124	417.0	COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,3J11D@40117|Nitrospirae	40117|Nitrospirae	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.1.15,1.8.7.1	ko:K00362,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00530	R00787,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YYD2_k127_3654616_0	717605.Theco_0315	2.57e-138	450.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,26QT9@186822|Paenibacillaceae	91061|Bacilli	P	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
YYD2_k127_3656087_2	880073.Calab_2251	3.544e-25	115.0	COG4775@1|root,COG4775@2|Bacteria,2NQXR@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD2_k127_3656087_3	118168.MC7420_2926	1.172e-12	83.0	COG2911@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2982@2|Bacteria,1G1RU@1117|Cyanobacteria,1H71Y@1150|Oscillatoriales	1117|Cyanobacteria	U	function (DUF490)	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	DUF3971,DUF748,TamB
YYD2_k127_3656087_0	857293.CAAU_1776	2.333e-154	514.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,36DGD@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YYD2_k127_3656087_4	1051632.TPY_0986	3.479e-10	67.0	COG0721@1|root,COG0721@2|Bacteria,1VPYV@1239|Firmicutes	1239|Firmicutes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YYD2_k127_3656087_1	1121468.AUBR01000017_gene2371	1.199e-152	500.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD2_k127_3683856_0	945713.IALB_2314	2.491e-32	141.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
YYD2_k127_3683856_1	234267.Acid_2705	3.606e-12	78.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD2_k127_3687767_0	1192034.CAP_4099	2.594e-13	85.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.107	ko:K04771,ko:K11749	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,PDZ,PDZ_2,Peptidase_S41,Trypsin_2
YYD2_k127_3687767_1	930169.B5T_03804	0.0001961	51.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XJFF@135619|Oceanospirillales	135619|Oceanospirillales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YYD2_k127_3704734_1	1121346.KB899808_gene3366	7.929e-33	131.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli,26S37@186822|Paenibacillaceae	91061|Bacilli	J	Metal-dependent phosphoesterase	php	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
YYD2_k127_3704734_0	1379698.RBG1_1C00001G0460	0.0	1132.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
YYD2_k127_371655_0	472759.Nhal_1913	3.347e-220	695.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X04H@135613|Chromatiales	135613|Chromatiales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YYD2_k127_3721500_0	1379698.RBG1_1C00001G1263	1.531e-45	180.0	COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_3721500_1	1122611.KB903953_gene5733	3.482e-07	61.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4EICR@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
YYD2_k127_3724421_0	395961.Cyan7425_3876	5.25e-29	132.0	COG2244@1|root,COG2244@2|Bacteria,1G4VC@1117|Cyanobacteria	1117|Cyanobacteria	S	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YYD2_k127_3724421_1	498761.HM1_1182	5.698e-17	85.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,24GPH@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
YYD2_k127_3759344_0	756272.Plabr_0410	8.41e-74	257.0	COG5587@1|root,COG5587@2|Bacteria,2J2RK@203682|Planctomycetes	203682|Planctomycetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
YYD2_k127_3759344_2	1036674.A28LD_0671	8.347e-20	104.0	2DPEU@1|root,331SS@2|Bacteria,1NDKB@1224|Proteobacteria,1RTE7@1236|Gammaproteobacteria,2QG29@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
YYD2_k127_3759344_1	1280950.HJO_04200	7.006e-33	140.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,43XF3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_6,Hydrolase_like,NTP_transferase
YYD2_k127_375980_0	1121472.AQWN01000008_gene2021	3.161e-44	182.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,24GPH@186801|Clostridia,260YH@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
YYD2_k127_375980_1	448385.sce8918	2.882e-41	168.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_3766508_1	309807.SRU_2713	1.723e-06	61.0	COG3210@1|root,COG4412@1|root,COG3210@2|Bacteria,COG4412@2|Bacteria,4PEZ5@976|Bacteroidetes,1FJW1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Laminin_G_3
YYD2_k127_3766508_0	264732.Moth_0241	1.388e-31	143.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Calx-beta,DUF11,DUF1573,F5_F8_type_C,FG-GAP,Glyco_hyd_101C,Glyco_hydro_101,NPCBM_assoc,SASA
YYD2_k127_3788151_5	1003195.SCAT_5069	3.949e-10	72.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
YYD2_k127_3788151_0	330214.NIDE2199	2.308e-73	267.0	COG2206@1|root,COG2206@2|Bacteria,3J14V@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD
YYD2_k127_3788151_3	443144.GM21_0234	3.699e-40	169.0	COG1413@1|root,COG1413@2|Bacteria,1NYRW@1224|Proteobacteria,430VV@68525|delta/epsilon subdivisions,2WVZE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3788151_4	471854.Dfer_3145	3.066e-10	74.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
YYD2_k127_3788151_1	290397.Adeh_4094	2.583e-55	196.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
YYD2_k127_3788151_2	404589.Anae109_2242	6.151e-54	196.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42SK2@68525|delta/epsilon subdivisions,2WPB3@28221|Deltaproteobacteria,2Z0CU@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD2_k127_3790133_0	1292020.H483_0106975	1.312e-05	55.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria	201174|Actinobacteria	M	Lipid A biosynthesis	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
YYD2_k127_3795427_0	1453500.AT05_08675	3.027e-44	170.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1HYQC@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_3795427_2	478741.JAFS01000001_gene1111	9.816e-13	81.0	COG0392@1|root,COG0392@2|Bacteria,46YYT@74201|Verrucomicrobia,37GP8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD2_k127_3795427_1	1499967.BAYZ01000103_gene3728	1.728e-38	147.0	COG2350@1|root,COG2350@2|Bacteria,2NR74@2323|unclassified Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
YYD2_k127_3802057_0	861299.J421_5978	1.551e-69	243.0	COG1940@1|root,COG1940@2|Bacteria,1ZSZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
YYD2_k127_3802057_2	511051.CSE_08830	2.601e-11	76.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YYD2_k127_3802057_1	404589.Anae109_1471	2.567e-34	143.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
YYD2_k127_3802587_0	998674.ATTE01000001_gene3400	1.173e-45	182.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
YYD2_k127_3806021_0	1123267.JONN01000001_gene1238	4.647e-235	764.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
YYD2_k127_3806021_1	1123267.JONN01000001_gene1239	8.376e-24	110.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YYD2_k127_3806021_4	1237149.C900_03046	1.167e-06	61.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47NGK@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YYD2_k127_3806021_2	42256.RradSPS_1688	9.829e-17	92.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3806620_2	1379698.RBG1_1C00001G1107	1.345e-33	134.0	COG1207@1|root,COG1207@2|Bacteria,2NQ8F@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
YYD2_k127_3806620_0	880072.Desac_2413	1.622e-131	428.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria,2MR4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4921)	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
YYD2_k127_3806620_1	945713.IALB_1452	1.228e-121	409.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YYD2_k127_3816459_0	404589.Anae109_1836	2.291e-77	276.0	COG3005@1|root,COG3005@2|Bacteria,1QYGG@1224|Proteobacteria,42NFU@68525|delta/epsilon subdivisions,2WKHN@28221|Deltaproteobacteria,2Z2AP@29|Myxococcales	28221|Deltaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
YYD2_k127_3816459_1	272943.RSP_1168	1.967e-16	94.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,1FATS@1060|Rhodobacter	28211|Alphaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
YYD2_k127_3819737_1	314230.DSM3645_01871	2.851e-25	108.0	COG0243@1|root,COG0243@2|Bacteria,2IXVV@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
YYD2_k127_3819737_2	448385.sce1473	1.948e-12	70.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YYD2_k127_3819737_0	330214.NIDE3218	5.595e-74	264.0	COG0388@1|root,COG0388@2|Bacteria,3J11H@40117|Nitrospirae	40117|Nitrospirae	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
YYD2_k127_3819737_3	713586.KB900536_gene1479	0.0007388	49.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
YYD2_k127_3819978_0	56780.SYN_02082	2.89e-306	970.0	COG0744@1|root,COG5009@1|root,COG0744@2|Bacteria,COG5009@2|Bacteria,1NRPB@1224|Proteobacteria,42ZB6@68525|delta/epsilon subdivisions,2WTUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
YYD2_k127_3824189_1	518766.Rmar_1484	9.792e-06	57.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
YYD2_k127_3824189_0	37682.EMT22473	3.017e-09	59.0	COG0820@1|root,2QV91@2759|Eukaryota,37KF1@33090|Viridiplantae,3GDQQ@35493|Streptophyta,3KRYP@4447|Liliopsida,3IGJR@38820|Poales	35493|Streptophyta	J	4Fe-4S single cluster domain	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
YYD2_k127_3828044_0	983917.RGE_05590	3.376e-69	240.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,1KMBQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	hmsR	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
YYD2_k127_3828044_1	1202768.JROF01000018_gene2905	1.982e-05	56.0	arCOG04998@1|root,arCOG04998@2157|Archaea,2Y7YH@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3828044_2	1379698.RBG1_1C00001G0462	5.458e-05	49.0	COG2067@1|root,COG2067@2|Bacteria,2NPVZ@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3828639_5	867903.ThesuDRAFT_01750	1.984e-10	71.0	COG0419@1|root,COG0419@2|Bacteria,1UMHS@1239|Firmicutes,25GIK@186801|Clostridia,3WDIT@538999|Clostridiales incertae sedis	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
YYD2_k127_3828639_4	867903.ThesuDRAFT_01750	3.167e-19	92.0	COG0419@1|root,COG0419@2|Bacteria,1UMHS@1239|Firmicutes,25GIK@186801|Clostridia,3WDIT@538999|Clostridiales incertae sedis	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
YYD2_k127_3828639_0	292459.STH2307	1.284e-58	219.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
YYD2_k127_3828639_2	1459636.NTE_01016	9.375e-40	154.0	COG2947@1|root,arCOG08640@2157|Archaea,41SK6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YYD2_k127_3828639_3	1191523.MROS_0441	5.106e-35	143.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD2_k127_3828639_1	391625.PPSIR1_21764	3.478e-40	151.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
YYD2_k127_3833676_2	521674.Plim_3986	1.972e-108	366.0	COG4531@1|root,COG4531@2|Bacteria,2IY65@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3833676_4	502025.Hoch_2415	5.426e-56	212.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z0GX@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD2_k127_3833676_5	502025.Hoch_2415	2.676e-49	203.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z0GX@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD2_k127_3833676_1	344747.PM8797T_11856	2.698e-213	672.0	COG5557@1|root,COG5557@2|Bacteria,2IWYN@203682|Planctomycetes	203682|Planctomycetes	C	Polysulphide reductase	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
YYD2_k127_3833676_0	1128421.JAGA01000003_gene2870	1.041e-289	927.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
YYD2_k127_3833676_3	344747.PM8797T_11846	2.156e-88	296.0	COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
YYD2_k127_3833676_7	1380384.JADN01000006_gene2727	2.163e-06	59.0	COG3420@1|root,COG4886@1|root,COG3420@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Laminin_G_3
YYD2_k127_3836316_0	386456.JQKN01000002_gene2422	6.328e-118	396.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,23NUT@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
YYD2_k127_3836316_1	868131.MSWAN_1300	1.535e-106	380.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,23NX2@183925|Methanobacteria	183925|Methanobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,tRNA-synt_2d
YYD2_k127_3836316_2	1452718.JBOY01000028_gene97	1.156e-21	106.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
YYD2_k127_3847542_1	234267.Acid_0265	2.94e-62	232.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
YYD2_k127_3847542_0	880073.Calab_3793	9.145e-201	635.0	COG0442@1|root,COG0442@2|Bacteria,2NNKF@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
YYD2_k127_3847542_2	1265505.ATUG01000002_gene1947	1.016e-13	75.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42QM3@68525|delta/epsilon subdivisions,2WKI2@28221|Deltaproteobacteria,2MI4S@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YYD2_k127_3848430_0	639030.JHVA01000001_gene3822	1.163e-144	464.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria,2JIC4@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD2_k127_3848430_2	1243664.CAVL020000005_gene328	6.435e-42	174.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,1ZBB5@1386|Bacillus	91061|Bacilli	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iYO844.BSU28450	Sdh_cyt
YYD2_k127_3848430_1	644282.Deba_1277	4.001e-68	244.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
YYD2_k127_3852554_7	984262.SGRA_1641	0.0005523	52.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1IXQD@117747|Sphingobacteriia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YYD2_k127_3852554_1	751944.HALDL1_10980	2.164e-113	376.0	COG0451@1|root,arCOG01369@2157|Archaea,2Y7SY@28890|Euryarchaeota,23SBI@183963|Halobacteria	183963|Halobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD2_k127_3852554_2	1125863.JAFN01000001_gene2936	7.627e-47	190.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07710	ko02020,map02020	M00500,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
YYD2_k127_3852554_0	269799.Gmet_0555	1.329e-124	414.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_3852554_4	1379698.RBG1_1C00001G0332	1.904e-24	109.0	COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
YYD2_k127_3852554_6	420246.GTNG_2449	1.064e-06	60.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1WFKD@129337|Geobacillus	91061|Bacilli	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YYD2_k127_3852554_3	631454.N177_1337	1.081e-30	136.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,1JP8P@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_3852554_5	1249975.JQLP01000005_gene1538	2.22e-15	81.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA_1	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD2_k127_3858389_1	880073.Calab_2081	3.938e-08	64.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
YYD2_k127_3858389_4	1123508.JH636439_gene1383	0.000208	53.0	COG0526@1|root,COG0526@2|Bacteria,2IZ08@203682|Planctomycetes	203682|Planctomycetes	CO	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3858389_3	1254432.SCE1572_42170	4.401e-05	55.0	COG1947@1|root,COG1947@2|Bacteria,1Q9QD@1224|Proteobacteria,434IQ@68525|delta/epsilon subdivisions,2WYVY@28221|Deltaproteobacteria,2Z0RW@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3858389_2	742727.HMPREF9447_02029	7.465e-06	55.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,2FQ5H@200643|Bacteroidia,4ANSR@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3858389_0	459349.CLOAM1883	2.084e-31	131.0	COG0526@1|root,COG0526@2|Bacteria,2NRMM@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin-like	resA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,Redoxin
YYD2_k127_3863556_0	644966.Tmar_0901	1.961e-142	469.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
YYD2_k127_3863556_1	1545915.JROG01000009_gene2807	1.548e-08	62.0	COG4447@1|root,COG4447@2|Bacteria,1R9D5@1224|Proteobacteria,2UPW4@28211|Alphaproteobacteria,2K9S4@204457|Sphingomonadales	204457|Sphingomonadales	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_386918_6	1128421.JAGA01000002_gene1077	1.334e-08	62.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1,DUF4399
YYD2_k127_386918_1	865861.AZSU01000002_gene3030	9.879e-120	396.0	COG1172@1|root,COG1172@2|Bacteria,1TSDH@1239|Firmicutes,247VP@186801|Clostridia,36HI2@31979|Clostridiaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
YYD2_k127_386918_3	688269.Theth_1907	2.173e-97	342.0	COG1172@1|root,COG1172@2|Bacteria,2GDW6@200918|Thermotogae	200918|Thermotogae	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
YYD2_k127_386918_0	592015.HMPREF1705_00674	5.516e-179	587.0	COG1129@1|root,COG1129@2|Bacteria,3TA0G@508458|Synergistetes	508458|Synergistetes	G	PFAM ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
YYD2_k127_386918_2	688269.Theth_1904	1.129e-108	364.0	COG0683@1|root,COG0683@2|Bacteria,2GDRX@200918|Thermotogae	200918|Thermotogae	E	Protein of unknown function (DUF3798)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3798
YYD2_k127_386918_5	1128421.JAGA01000002_gene1022	4.965e-72	250.0	COG0812@1|root,COG0812@2|Bacteria,2NPHQ@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD2_k127_3890495_0	1449126.JQKL01000005_gene923	6.125e-161	525.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,267JT@186813|unclassified Clostridiales	186801|Clostridia	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2
YYD2_k127_3890495_3	1047013.AQSP01000057_gene1924	3.642e-07	61.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
YYD2_k127_3890495_2	926567.TheveDRAFT_1797	2.563e-13	78.0	COG2110@1|root,COG2110@2|Bacteria,3TB5Z@508458|Synergistetes	508458|Synergistetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
YYD2_k127_3890495_1	1207063.P24_13558	2.465e-21	104.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,2JPVK@204441|Rhodospirillales	204441|Rhodospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD2_k127_39018_1	926569.ANT_20600	2.251e-06	55.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_39018_0	357808.RoseRS_1092	1.456e-187	621.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2G64C@200795|Chloroflexi,376K3@32061|Chloroflexia	32061|Chloroflexia	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
YYD2_k127_3903217_7	349124.Hhal_0891	9.274e-20	96.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1WYGP@135613|Chromatiales	135613|Chromatiales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
YYD2_k127_3903217_3	644966.Tmar_2171	4.001e-85	310.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia	186801|Clostridia	O	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
YYD2_k127_3903217_1	644966.Tmar_2172	6.065e-97	327.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3WCEH@538999|Clostridiales incertae sedis	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YYD2_k127_3903217_9	1298920.KI911353_gene4100	1.835e-09	66.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,21XFR@1506553|Lachnoclostridium	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	ushA	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
YYD2_k127_3903217_2	671143.DAMO_2568	3.177e-93	313.0	COG1432@1|root,COG1432@2|Bacteria,2NQWI@2323|unclassified Bacteria	2|Bacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
YYD2_k127_3903217_0	1304880.JAGB01000002_gene1835	9.119e-195	624.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YYD2_k127_3903217_8	478741.JAFS01000001_gene2221	2.654e-10	71.0	COG5652@1|root,COG5652@2|Bacteria,46Z0R@74201|Verrucomicrobia,37GZJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YYD2_k127_3903217_6	986075.CathTA2_1331	6.14e-26	112.0	COG1762@1|root,COG1762@2|Bacteria,1VA2N@1239|Firmicutes,4HJYU@91061|Bacilli	91061|Bacilli	G	PTS fructose transporter subunit IIA	-	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
YYD2_k127_3903217_4	448385.sce1432	3.076e-69	267.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Pkinase,Sigma54_activat
YYD2_k127_3903217_5	243231.GSU1870	2.876e-29	132.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria,43W33@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD2_k127_3905714_3	1121403.AUCV01000001_gene880	5.594e-22	108.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2MMM3@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
YYD2_k127_3905714_1	909663.KI867151_gene3006	9.97e-107	361.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2MQBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
YYD2_k127_3905714_0	485913.Krac_0576	2.57e-125	409.0	COG0451@1|root,COG0451@2|Bacteria,2G8UC@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YYD2_k127_3905714_2	215803.DB30_5754	5.448e-91	307.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
YYD2_k127_3914373_0	379066.GAU_2946	2.427e-18	100.0	COG4206@1|root,COG4774@1|root,COG4206@2|Bacteria,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YYD2_k127_391500_0	926561.KB900620_gene3233	2.568e-194	629.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WA8Y@53433|Halanaerobiales	186801|Clostridia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YYD2_k127_391500_1	1340493.JNIF01000004_gene171	2.256e-105	348.0	COG1209@1|root,COG1209@2|Bacteria,3Y2ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD2_k127_391500_2	219305.MCAG_04709	5.035e-09	69.0	COG2244@1|root,COG2244@2|Bacteria,2GRGT@201174|Actinobacteria	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
YYD2_k127_3920614_1	1203606.HMPREF1526_00134	5.786e-09	59.0	COG0169@1|root,COG0703@1|root,COG0169@2|Bacteria,COG0703@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,36E3G@31979|Clostridiaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
YYD2_k127_3920614_2	319795.Dgeo_1396	9.759e-09	62.0	COG1826@1|root,COG1826@2|Bacteria,1WKBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YYD2_k127_3920614_0	945713.IALB_2905	4.153e-37	153.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3921542_1	944547.ABLL_0450	6.526e-43	163.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2YPIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
YYD2_k127_3921542_0	118005.AWNK01000006_gene1206	9.765e-113	377.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YYD2_k127_3921542_2	404589.Anae109_1294	1.386e-15	84.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
YYD2_k127_3931156_14	1121406.JAEX01000002_gene904	2.691e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2M93P@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
YYD2_k127_3931156_1	518766.Rmar_0643	1.631e-147	511.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1FIP5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YYD2_k127_3931156_9	743721.Psesu_2959	1.612e-37	154.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1X5D1@135614|Xanthomonadales	135614|Xanthomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YYD2_k127_3931156_6	1379698.RBG1_1C00001G0197	6.839e-61	220.0	COG1521@1|root,COG1521@2|Bacteria,2NP3Z@2323|unclassified Bacteria	2|Bacteria	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
YYD2_k127_3931156_10	118173.KB235914_gene2937	6.268e-29	117.0	COG0234@1|root,COG0234@2|Bacteria,1G6J1@1117|Cyanobacteria,1HBIM@1150|Oscillatoriales	1117|Cyanobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YYD2_k127_3931156_0	518766.Rmar_1918	7.402e-218	688.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1FIJH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD2_k127_3931156_11	871968.DESME_00405	7.388e-15	81.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262E7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
YYD2_k127_3931156_8	1234364.AMSF01000015_gene3257	1.489e-37	153.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1X6UH@135614|Xanthomonadales	135614|Xanthomonadales	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK2	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
YYD2_k127_3931156_4	880073.Calab_2860	1.02e-70	254.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
YYD2_k127_3931156_2	909663.KI867151_gene3047	3.508e-94	319.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2MQ99@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YYD2_k127_3931156_3	1128421.JAGA01000002_gene351	8.772e-72	265.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YYD2_k127_3931156_5	290315.Clim_0309	4.655e-61	229.0	COG1207@1|root,COG1207@2|Bacteria,1FDEZ@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.23	ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
YYD2_k127_3931156_13	1121104.AQXH01000009_gene2244	2.218e-08	63.0	COG1316@1|root,COG1316@2|Bacteria,4P5Q5@976|Bacteroidetes	976|Bacteroidetes	K	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
YYD2_k127_3931156_12	883096.HMPREF9699_01815	1.388e-10	64.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YYD2_k127_3931156_7	448385.sce0363	8.39e-51	193.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_3931613_3	357808.RoseRS_1234	8.185e-12	66.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_3931613_2	357808.RoseRS_1235	2.498e-24	116.0	COG5662@1|root,COG5662@2|Bacteria,2G7G7@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3931613_0	526227.Mesil_0789	9.253e-94	319.0	COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_3931613_1	383372.Rcas_3764	7.719e-69	243.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
YYD2_k127_3935076_1	518766.Rmar_0140	7.167e-20	105.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4P5KZ@976|Bacteroidetes,1FJUW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD2_k127_3935076_0	1166018.FAES_3476	5.268e-29	136.0	COG0526@1|root,COG1729@1|root,COG0526@2|Bacteria,COG1729@2|Bacteria,4NKFI@976|Bacteroidetes,47MM5@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
YYD2_k127_3940324_2	1392486.JIAF01000003_gene637	6.36e-17	94.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YYD2_k127_3940324_0	880073.Calab_0866	1.263e-49	194.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
YYD2_k127_3940324_1	1379698.RBG1_1C00001G0810	2.977e-44	168.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
YYD2_k127_3940324_3	1193181.BN10_300071	2.173e-11	66.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4FH0J@85021|Intrasporangiaceae	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD2_k127_3941104_1	502025.Hoch_3592	1.837e-101	340.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2Z2XK@29|Myxococcales	28221|Deltaproteobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YYD2_k127_3941104_0	1379698.RBG1_1C00001G1488	3.334e-122	403.0	COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD2_k127_3941104_2	1122176.KB903619_gene5336	4.632e-20	104.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1INQF@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YYD2_k127_3943185_1	1379698.RBG1_1C00001G0779	6.628e-69	264.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YYD2_k127_3943185_0	671143.DAMO_0821	2.674e-142	463.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
YYD2_k127_3943185_3	1379698.RBG1_1C00001G0781	7.297e-44	166.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
YYD2_k127_3943185_4	1535422.ND16A_3836	7.663e-34	144.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,1RWBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3
YYD2_k127_3943185_2	1379698.RBG1_1C00001G1080	3.789e-53	196.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YYD2_k127_3944481_0	1484157.PSNIH2_17045	1.906e-62	230.0	COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,3VZ2J@53335|Pantoea	1236|Gammaproteobacteria	G	Lipopolysaccharide biosynthesis protein	walW	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_3953346_0	234267.Acid_3454	3.239e-34	151.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	57723|Acidobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
YYD2_k127_3953346_1	234267.Acid_3455	1.4e-25	115.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD2_k127_3955871_2	644282.Deba_1070	9.426e-33	129.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YYD2_k127_3955871_0	292459.STH1166	2.098e-130	426.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
YYD2_k127_3955871_3	1307761.L21SP2_0329	9.718e-19	91.0	COG1862@1|root,COG1862@2|Bacteria,2J8D6@203691|Spirochaetes	203691|Spirochaetes	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
YYD2_k127_3955871_1	1304880.JAGB01000001_gene685	3.043e-52	189.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YYD2_k127_3975980_0	1047013.AQSP01000144_gene809	1.125e-78	273.0	COG1215@1|root,COG1215@2|Bacteria,2NQUG@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_3975980_2	1121434.AULY01000006_gene486	4.257e-31	127.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2MCER@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YYD2_k127_3975980_3	1283299.AUKG01000001_gene2771	4.43e-28	130.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
YYD2_k127_3975980_4	553178.CAPGI0001_1693	6.474e-20	93.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia,1ESC1@1016|Capnocytophaga	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YYD2_k127_3975980_1	880073.Calab_1105	2.089e-46	193.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
YYD2_k127_3983157_0	1123242.JH636436_gene298	1.896e-38	153.0	COG1845@1|root,COG1845@2|Bacteria,2IYXN@203682|Planctomycetes	203682|Planctomycetes	C	Heme copper-type cytochrome quinol oxidase, subunit	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YYD2_k127_3983157_1	1192034.CAP_2034	1.988e-25	117.0	2DR0H@1|root,339NS@2|Bacteria,1R3N7@1224|Proteobacteria,42X1P@68525|delta/epsilon subdivisions,2X8S7@28221|Deltaproteobacteria,2Z3NK@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
YYD2_k127_3983157_2	1411123.JQNH01000001_gene1791	5.406e-24	108.0	COG1845@1|root,COG1845@2|Bacteria,1MXAB@1224|Proteobacteria,2TRFQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YYD2_k127_3989012_0	671143.DAMO_0004	9.25e-72	260.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD2_k127_3989012_1	314285.KT71_18736	3.165e-06	58.0	COG1404@1|root,COG1520@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	rhs family	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
YYD2_k127_401061_1	502025.Hoch_0385	4.817e-65	227.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	-	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
YYD2_k127_401061_2	1123508.JH636441_gene3394	1.761e-06	58.0	COG1595@1|root,COG1595@2|Bacteria,2J04K@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YYD2_k127_401061_0	1210884.HG799471_gene14563	4.303e-70	249.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_4044579_1	880073.Calab_1132	8.935e-98	338.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD2_k127_4044579_0	243231.GSU2431	1.038e-113	379.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
YYD2_k127_4046103_0	448385.sce2737	0.0	1090.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WTZ0@28221|Deltaproteobacteria,2YUKM@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
YYD2_k127_4046103_1	1242864.D187_001942	1.11e-90	320.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42T6A@68525|delta/epsilon subdivisions,2WPV8@28221|Deltaproteobacteria,2YUNA@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
YYD2_k127_4052962_1	1379698.RBG1_1C00001G0991	2.744e-07	60.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
YYD2_k127_4052962_0	903818.KI912268_gene2712	2.517e-133	436.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
YYD2_k127_4057430_2	56780.SYN_02636	1.863e-62	229.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
YYD2_k127_4057430_1	324057.Pjdr2_0486	3.528e-82	285.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,26SQU@186822|Paenibacillaceae	91061|Bacilli	C	Electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
YYD2_k127_4057430_3	867903.ThesuDRAFT_02082	1.328e-48	178.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3WDHI@538999|Clostridiales incertae sedis	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
YYD2_k127_4057430_5	1123371.ATXH01000012_gene1469	6.753e-27	123.0	COG1082@1|root,COG1082@2|Bacteria,2GGQY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD2_k127_4057430_4	398767.Glov_3074	9.889e-37	155.0	COG4191@1|root,COG4191@2|Bacteria,1QUMH@1224|Proteobacteria,42MM2@68525|delta/epsilon subdivisions,2X7N8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD2_k127_4057430_0	1232410.KI421416_gene2592	2.068e-116	391.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_4064558_1	1385935.N836_10115	1.66e-14	76.0	COG0500@1|root,COG2226@2|Bacteria,1G3CH@1117|Cyanobacteria,1HAB6@1150|Oscillatoriales	1117|Cyanobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD2_k127_4064558_0	1499967.BAYZ01000069_gene1838	8.047e-123	411.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YYD2_k127_406493_0	1122165.AUHS01000015_gene699	1.158e-109	375.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD2_k127_406493_1	272624.lpg1676	1.225e-42	173.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YYD2_k127_4070084_1	945713.IALB_0147	4.077e-31	139.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
YYD2_k127_4070084_0	740709.A10D4_00975	5.172e-64	247.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
YYD2_k127_4086985_1	404589.Anae109_1317	1.008e-23	102.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RQR@68525|delta/epsilon subdivisions,2WNTF@28221|Deltaproteobacteria,2Z0PC@29|Myxococcales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YYD2_k127_4086985_0	1370121.AUWS01000024_gene2538	2.875e-122	421.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	pknK_2	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
YYD2_k127_4087881_2	179408.Osc7112_1646	1.718e-21	95.0	COG1085@1|root,COG1085@2|Bacteria,1G1CA@1117|Cyanobacteria,1H82Z@1150|Oscillatoriales	1117|Cyanobacteria	C	galactose-1-phosphate	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf,HIT
YYD2_k127_4087881_0	1499683.CCFF01000013_gene324	3.716e-199	629.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YYD2_k127_4087881_1	1047013.AQSP01000142_gene242	3.633e-134	451.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
YYD2_k127_4092359_0	945713.IALB_2711	5.626e-72	250.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_4092359_1	1283299.AUKG01000002_gene4917	6.927e-39	157.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
YYD2_k127_4095598_1	401526.TcarDRAFT_1170	1.507e-39	151.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4H4DD@909932|Negativicutes	909932|Negativicutes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YYD2_k127_4095598_2	1122164.JHWF01000022_gene1733	1.544e-07	53.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4095598_4	1121355.KB903379_gene745	0.0002768	48.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YYD2_k127_4095598_0	1278073.MYSTI_01113	1.683e-43	164.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YYD2_k127_4096263_0	518766.Rmar_2727	5.487e-07	63.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1072	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
YYD2_k127_4096263_1	1227497.C491_14887	7.96e-05	56.0	COG3420@1|root,arCOG02519@2157|Archaea,2XTQ7@28890|Euryarchaeota,23TF0@183963|Halobacteria	183963|Halobacteria	P	Nitrous oxidase accessory protein	nosD1	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,NosL
YYD2_k127_4097306_0	502025.Hoch_6065	3.098e-16	91.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2Z301@29|Myxococcales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YYD2_k127_4097306_1	706587.Desti_3709	2.67e-11	75.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,2MS4A@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YYD2_k127_4097306_2	1265505.ATUG01000001_gene2843	0.0003645	49.0	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria,2MKBA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YYD2_k127_4115203_0	518766.Rmar_1770	1.808e-99	333.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1FJR1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ABC transporter	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_4115203_2	1313304.CALK_1619	3.247e-58	222.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
YYD2_k127_4115203_3	545694.TREPR_2502	5.495e-48	192.0	COG3225@1|root,COG3225@2|Bacteria,2J6NB@203691|Spirochaetes	203691|Spirochaetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
YYD2_k127_4115203_4	377629.TERTU_2532	2.052e-10	73.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,2PQB7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YYD2_k127_4115203_1	502025.Hoch_5266	4.554e-87	296.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria,2YUTV@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
YYD2_k127_4119480_2	1125863.JAFN01000001_gene4	8.069e-59	216.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42QZK@68525|delta/epsilon subdivisions,2WMZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
YYD2_k127_4119480_1	1265505.ATUG01000002_gene1830	4.038e-61	228.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria,2MJ0F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YYD2_k127_4119480_0	1379698.RBG1_1C00001G0907	1.877e-147	476.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YYD2_k127_4119480_4	457570.Nther_2211	8.33e-45	179.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
YYD2_k127_4119480_6	1121440.AUMA01000003_gene2819	2.536e-16	89.0	COG2068@1|root,COG2068@2|Bacteria,1RAAE@1224|Proteobacteria,42QNZ@68525|delta/epsilon subdivisions,2WNX6@28221|Deltaproteobacteria,2MG8P@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD,NTP_transf_3
YYD2_k127_4119480_5	1379698.RBG1_1C00001G0893	9.287e-32	135.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
YYD2_k127_4119480_3	1232410.KI421419_gene2458	1.059e-47	175.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,43TIS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YYD2_k127_4134131_0	1380386.JIAW01000001_gene4883	1.034e-51	187.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,239UW@1762|Mycobacteriaceae	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_4134131_1	1151126.AQYI01000006_gene2751	9.967e-06	58.0	COG4932@1|root,COG4932@2|Bacteria,2HU92@201174|Actinobacteria,4FSW9@85023|Microbacteriaceae	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD2_k127_413896_0	880073.Calab_0233	1.527e-168	537.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YYD2_k127_413896_2	264201.pc1671	7.862e-24	111.0	COG0712@1|root,COG0712@2|Bacteria,2JGGM@204428|Chlamydiae	204428|Chlamydiae	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YYD2_k127_413896_3	765952.PUV_23590	7.21e-22	102.0	COG0711@1|root,COG0711@2|Bacteria,2JGAI@204428|Chlamydiae	204428|Chlamydiae	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
YYD2_k127_413896_4	1379698.RBG1_1C00001G0147	1.296e-18	87.0	COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
YYD2_k127_413896_1	1379698.RBG1_1C00001G0146	1.626e-67	248.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
YYD2_k127_413896_6	1379698.RBG1_1C00001G0145	5.363e-05	51.0	2EPKR@1|root,33H7C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_413896_5	1437425.CSEC_0646	8.334e-07	55.0	2EQQP@1|root,33IAK@2|Bacteria,2JGJU@204428|Chlamydiae	204428|Chlamydiae	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
YYD2_k127_4178186_0	479434.Sthe_3075	2.632e-28	132.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
YYD2_k127_4178862_0	1210884.HG799463_gene9368	6.011e-37	158.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YYD2_k127_4179136_0	1121957.ATVL01000014_gene1459	4.793e-54	207.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4179136_1	886293.Sinac_1860	1.56e-08	68.0	COG1807@1|root,COG1807@2|Bacteria,2J21M@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_4179136_2	1463820.JOGW01000001_gene5468	0.0005676	52.0	COG1807@1|root,COG1807@2|Bacteria,2GP96@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_419276_1	391625.PPSIR1_01909	2.207e-16	85.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2X5AW@28221|Deltaproteobacteria,2Z34Y@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
YYD2_k127_419276_2	1128421.JAGA01000002_gene1077	4.906e-11	69.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1,DUF4399
YYD2_k127_4200015_0	1123242.JH636434_gene3359	1.237e-205	657.0	COG1166@1|root,COG1166@2|Bacteria,2IX6P@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YYD2_k127_4200015_2	1121085.AUCI01000001_gene3663	4.285e-11	74.0	COG4818@1|root,COG4818@2|Bacteria,1VBIZ@1239|Firmicutes,4HKBZ@91061|Bacilli,1ZJCH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
YYD2_k127_4200015_1	1379698.RBG1_1C00001G0425	1.175e-56	210.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD2_k127_4207006_2	868131.MSWAN_0806	6.869e-05	56.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YYD2_k127_4207006_0	1379698.RBG1_1C00001G0286	5.294e-19	102.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	1379698.RBG1_1C00001G0286|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4207006_1	765420.OSCT_2114	3.022e-13	79.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
YYD2_k127_4210061_0	760568.Desku_0657	3.252e-104	362.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YYD2_k127_4226272_0	379066.GAU_1920	9.456e-80	286.0	COG1629@1|root,COG4771@2|Bacteria,1ZST4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CarboxypepD_reg-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD2_k127_4233948_0	243233.MCA2124	2.794e-61	228.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_4237401_0	671143.DAMO_1298	1.687e-123	409.0	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_4237401_2	1125863.JAFN01000001_gene848	4.551e-39	168.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,42R9V@68525|delta/epsilon subdivisions,2WN4M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
YYD2_k127_4237401_3	1049564.TevJSym_au00200	1.304e-05	49.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1J6EW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	P COG0025 NhaP-type Na H and K H antiporters	-	-	-	ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Na_H_Exchanger
YYD2_k127_4237401_1	1123242.JH636435_gene2052	2.482e-45	168.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YYD2_k127_4242300_2	1307761.L21SP2_1151	0.0003573	49.0	COG2227@1|root,COG2227@2|Bacteria,2J6CB@203691|Spirochaetes	203691|Spirochaetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD2_k127_4242300_0	1192034.CAP_7240	8.873e-37	156.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_4242300_1	518766.Rmar_0744	6.976e-06	50.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_4247354_1	1304883.KI912532_gene1603	2.66e-14	73.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,2KVSV@206389|Rhodocyclales	206389|Rhodocyclales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_4247354_2	1205680.CAKO01000041_gene5510	0.0004566	43.0	COG0810@1|root,COG0810@2|Bacteria,1NJ1R@1224|Proteobacteria,2UGFN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD2_k127_4247354_0	1382359.JIAL01000001_gene1199	9.663e-47	185.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
YYD2_k127_4249512_2	521674.Plim_2252	2.209e-09	62.0	COG1595@1|root,COG1595@2|Bacteria,2J08Y@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_4249512_3	1265505.ATUG01000001_gene3090	3.254e-07	62.0	COG4232@1|root,COG4232@2|Bacteria,1R1X1@1224|Proteobacteria,42SD6@68525|delta/epsilon subdivisions,2WP2I@28221|Deltaproteobacteria,2MKNH@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
YYD2_k127_4249512_0	266117.Rxyl_2540	5.911e-217	701.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
YYD2_k127_4249512_1	404589.Anae109_0191	8.82e-45	169.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria,2Z0K4@29|Myxococcales	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
YYD2_k127_4252694_4	929712.KI912613_gene2840	2.304e-30	135.0	COG2802@1|root,COG2802@2|Bacteria,2HP4R@201174|Actinobacteria,4CQGD@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
YYD2_k127_4252694_5	234267.Acid_3880	3.039e-12	79.0	COG1225@1|root,COG1225@2|Bacteria,3Y8N3@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD2_k127_4252694_2	1379698.RBG1_1C00001G1168	9.262e-119	393.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
YYD2_k127_4252694_1	1131269.AQVV01000024_gene2364	9.942e-123	410.0	COG0260@1|root,COG4398@1|root,COG0260@2|Bacteria,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	FIST,FIST_C,Peptidase_M17,Peptidase_M17_N
YYD2_k127_4252694_0	429009.Adeg_1398	1.977e-193	623.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,42EPX@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
YYD2_k127_4252694_3	911008.GLAD_01924	9.293e-72	249.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	elbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
YYD2_k127_4252694_6	452637.Oter_2809	7.943e-06	48.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,3K7SP@414999|Opitutae	414999|Opitutae	L	Helix-hairpin-helix domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8
YYD2_k127_4261653_0	316274.Haur_4643	5.538e-17	96.0	COG1572@1|root,COG1572@2|Bacteria,2G7MU@200795|Chloroflexi,374XB@32061|Chloroflexia	2|Bacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,Peptidase_M66,fn3
YYD2_k127_4300932_0	1300345.LF41_901	2.237e-128	432.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XDED@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
YYD2_k127_4300932_3	1121920.AUAU01000004_gene627	8.587e-33	147.0	COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD2_k127_4300932_2	794903.OPIT5_18650	2.563e-98	333.0	COG0845@1|root,COG0845@2|Bacteria,46U1B@74201|Verrucomicrobia,3K78A@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YYD2_k127_4300932_1	497964.CfE428DRAFT_2129	7.463e-99	327.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD2_k127_4301316_6	1442599.JAAN01000033_gene1630	1.177e-24	113.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1X503@135614|Xanthomonadales	135614|Xanthomonadales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
YYD2_k127_4301316_8	459349.CLOAM0180	9.147e-10	65.0	COG1188@1|root,COG1188@2|Bacteria,2NQ1V@2323|unclassified Bacteria	2|Bacteria	J	S4 RNA-binding domain	yabO	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3558,S4
YYD2_k127_4301316_1	1121896.JMLU01000002_gene506	4.426e-49	186.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia,2NT0W@237|Flavobacterium	976|Bacteroidetes	D	Phosphonate ABC transporter ATP-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
YYD2_k127_4301316_7	879309.HMPREF9199_0791	2.393e-20	104.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
YYD2_k127_4301316_5	591001.Acfer_0659	1.956e-40	166.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes	909932|Negativicutes	D	Peptidase M23	envC_1	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YYD2_k127_4301316_4	518766.Rmar_2254	1.151e-41	176.0	COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1FJ1I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
YYD2_k127_4301316_3	880073.Calab_1952	8.145e-44	177.0	COG1774@1|root,COG1774@2|Bacteria,2NPEB@2323|unclassified Bacteria	2|Bacteria	S	PSP1 C-terminal conserved region	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	PSP1
YYD2_k127_4301316_0	1121430.JMLG01000016_gene389	1.954e-55	209.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,260P1@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YYD2_k127_4301316_2	1437606.BBOH_0660	7.189e-44	168.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CYS9@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YYD2_k127_4310415_4	694427.Palpr_1114	1.502e-20	105.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,2FV1K@200643|Bacteroidia,22Z9F@171551|Porphyromonadaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
YYD2_k127_4310415_2	96561.Dole_2327	3.528e-107	368.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MIBD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YYD2_k127_4310415_1	370438.PTH_2736	5.684e-134	468.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,260I5@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YYD2_k127_4310415_3	867903.ThesuDRAFT_00100	7.117e-69	244.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WD2S@538999|Clostridiales incertae sedis	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD2_k127_4310415_0	926550.CLDAP_29770	4.384e-141	471.0	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
YYD2_k127_4317283_0	290397.Adeh_4240	1.575e-134	444.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4M@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	sasR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_4317283_1	1144275.COCOR_01160	2.589e-80	290.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2X797@28221|Deltaproteobacteria,2YWR1@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	sasS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD2_k127_4317283_2	338963.Pcar_1648	1.449e-10	66.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,43TQX@69541|Desulfuromonadales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
YYD2_k127_4318395_0	357808.RoseRS_1092	1.425e-188	606.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2G64C@200795|Chloroflexi,376K3@32061|Chloroflexia	32061|Chloroflexia	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
YYD2_k127_4318395_1	266117.Rxyl_2933	0.0001317	49.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria	201174|Actinobacteria	S	CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
YYD2_k127_4321392_3	945713.IALB_1488	2.64e-07	60.0	COG3291@1|root,COG4409@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	wcoB	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,PKD,Reprolysin_4
YYD2_k127_4321392_1	671143.DAMO_0415	9.843e-95	316.0	COG0745@1|root,COG0745@2|Bacteria,2NQWD@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_4321392_0	671143.DAMO_0414	1.481e-298	940.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
YYD2_k127_4321392_2	1304872.JAGC01000003_gene2537	4.294e-43	161.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
YYD2_k127_4329921_0	1123508.JH636449_gene7284	2.241e-54	200.0	COG3459@1|root,COG3459@2|Bacteria,2IYJ0@203682|Planctomycetes	203682|Planctomycetes	G	Putative glucoamylase	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YYD2_k127_4329921_1	1122962.AULH01000027_gene3419	1.733e-05	57.0	28H8H@1|root,2Z7KE@2|Bacteria,1MV77@1224|Proteobacteria,2TSVV@28211|Alphaproteobacteria,371J1@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Aerotolerance regulator N-terminal	MA20_44655	-	-	-	-	-	-	-	-	-	-	-	BatA,DUF4159
YYD2_k127_4336984_1	324602.Caur_2628	7.082e-32	130.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
YYD2_k127_4336984_0	379066.GAU_3517	1.005e-55	199.0	COG0783@1|root,COG0783@2|Bacteria	2|Bacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
YYD2_k127_4336984_2	1869.MB27_11800	3.367e-06	58.0	COG1708@1|root,COG1708@2|Bacteria,2I1CC@201174|Actinobacteria	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YYD2_k127_4336984_3	1265313.HRUBRA_00729	0.0002932	45.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1J5K3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YYD2_k127_4342785_0	194439.CT1993	4.018e-113	391.0	COG0621@1|root,COG0621@2|Bacteria,1FDCV@1090|Chlorobi	1090|Chlorobi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YYD2_k127_4342785_1	589865.DaAHT2_1905	2.109e-52	194.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2MI7N@213118|Desulfobacterales	28221|Deltaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
YYD2_k127_4343777_0	1379698.RBG1_1C00001G0871	3.168e-86	306.0	COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YYD2_k127_4344287_1	1280390.CBQR020000048_gene957	7.923e-46	180.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
YYD2_k127_4344287_0	290397.Adeh_0870	2.524e-164	534.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
YYD2_k127_434716_2	1032480.MLP_27670	3.711e-88	297.0	COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria,4DVZ5@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_4,CPSase_L_D2
YYD2_k127_434716_1	861299.J421_0426	7.169e-139	452.0	COG0458@1|root,COG0458@2|Bacteria,1ZTAX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp
YYD2_k127_434716_0	1380393.JHVP01000005_gene3587	5.578e-179	569.0	COG0151@1|root,COG0151@2|Bacteria,2I624@201174|Actinobacteria,4EXFF@85013|Frankiales	201174|Actinobacteria	F	Carbamoyl-phosphate synthase L chain, ATP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_434716_3	1043205.AFYF01000045_gene2918	3.226e-57	211.0	COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria,4FETH@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
YYD2_k127_434716_4	1032480.MLP_53040	1.368e-07	65.0	COG2382@1|root,COG2382@2|Bacteria,2HJEA@201174|Actinobacteria,4DSCH@85009|Propionibacteriales	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
YYD2_k127_4347273_1	234267.Acid_0827	1.372e-27	116.0	COG1108@1|root,COG1108@2|Bacteria,3Y93X@57723|Acidobacteria	57723|Acidobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
YYD2_k127_4347273_0	502025.Hoch_3917	3.556e-49	191.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQ7S@28221|Deltaproteobacteria,2YTZ9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
YYD2_k127_4347273_2	1379698.RBG1_1C00001G0107	3.752e-18	96.0	COG3170@1|root,COG3170@2|Bacteria,2NPXD@2323|unclassified Bacteria	2|Bacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4352542_0	1396141.BATP01000030_gene3662	1.481e-06	61.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46Z1Z@74201|Verrucomicrobia,2IUA3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
YYD2_k127_435309_0	498211.CJA_1369	4.728e-07	59.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria,1FGM2@10|Cellvibrio	1236|Gammaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iB21_1397.B21_03429,iECBD_1354.ECBD_0105,iECB_1328.ECB_03478,iECD_1391.ECD_03478,iECNA114_1301.ECNA114_3774,iECSF_1327.ECSF_3456,iSF_1195.SF3661,iS_1188.S4107	Glyco_transf_9
YYD2_k127_436136_1	1379698.RBG1_1C00001G0978	1.652e-58	209.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YYD2_k127_436136_0	1379698.RBG1_1C00001G0979	1.196e-85	291.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD2_k127_436136_2	313596.RB2501_13264	4.976e-22	107.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YYD2_k127_436136_3	316274.Haur_3781	4.264e-20	93.0	COG0457@1|root,COG0457@2|Bacteria	316274.Haur_3781|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_43692_0	1229781.C272_15552	4.15e-05	51.0	COG2334@1|root,COG2334@2|Bacteria,2IKR1@201174|Actinobacteria,4F8Y8@85019|Brevibacteriaceae	201174|Actinobacteria	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD2_k127_43692_1	1223410.KN050846_gene2453	6.135e-05	55.0	COG2866@1|root,COG3291@1|root,COG4886@1|root,COG4935@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
YYD2_k127_43692_2	1179778.PMM47T1_06236	0.0006441	47.0	COG1595@1|root,COG1595@2|Bacteria,1RA91@1224|Proteobacteria,1SIR8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	foxI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_4373140_0	290397.Adeh_3062	5.864e-72	269.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YYD2_k127_4373140_1	1121937.AUHJ01000005_gene2153	7.223e-05	55.0	COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,1S4AZ@1236|Gammaproteobacteria,4695K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
YYD2_k127_4374300_2	1236976.JCM16418_3617	0.0002653	54.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1TRF1@1239|Firmicutes,4HI50@91061|Bacilli,274ZR@186822|Paenibacillaceae	91061|Bacilli	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
YYD2_k127_4374300_1	1500894.JQNN01000001_gene4265	6.114e-14	85.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria	2|Bacteria	Q	domain protein	sagI	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
YYD2_k127_4374300_0	867903.ThesuDRAFT_00747	1.274e-85	293.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WD2R@538999|Clostridiales incertae sedis	186801|Clostridia	V	ABC transporter	yfiL	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD2_k127_4387891_0	575540.Isop_2142	2.97e-204	647.0	COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
YYD2_k127_4389895_1	1496688.ER33_04910	1.932e-20	92.0	COG0277@1|root,COG0277@2|Bacteria,1G1U2@1117|Cyanobacteria,22SJ4@167375|Cyanobium	1117|Cyanobacteria	C	Glycolate oxidase subunit	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD2_k127_4389895_2	265729.GS18_0205945	7.085e-17	94.0	COG0277@1|root,COG0277@2|Bacteria,1TQMR@1239|Firmicutes,4HDHV@91061|Bacilli,1ZEDC@1386|Bacillus	91061|Bacilli	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD2_k127_4389895_0	562970.Btus_2619	2.268e-61	237.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,278U1@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
YYD2_k127_439970_4	580331.Thit_1977	5.023e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,42EPJ@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD2_k127_439970_0	880073.Calab_2123	3.282e-291	910.0	COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD2_k127_439970_3	1278073.MYSTI_04641	1.402e-59	209.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2YUYC@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YYD2_k127_439970_2	335541.Swol_2338	4.062e-61	213.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,42JWQ@68298|Syntrophomonadaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YYD2_k127_439970_1	1379698.RBG1_1C00001G1604	1.612e-287	908.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YYD2_k127_4402813_0	518766.Rmar_0472	3.206e-272	852.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1FIXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YYD2_k127_4402813_1	1449357.JQLK01000001_gene685	1.448e-18	93.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YYD2_k127_442106_0	1379698.RBG1_1C00001G1345	3.294e-143	476.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
YYD2_k127_442106_5	929556.Solca_3300	5.852e-15	81.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1IU3X@117747|Sphingobacteriia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD2_k127_442106_2	1379698.RBG1_1C00001G1850	5.278e-48	186.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD2_k127_442106_6	880073.Calab_2081	8.557e-14	85.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
YYD2_k127_442106_8	935866.JAER01000011_gene2258	0.000843	52.0	COG0737@1|root,COG2374@1|root,COG3942@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,COG3942@2|Bacteria,2GKC3@201174|Actinobacteria,4DUQV@85009|Propionibacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Big_3_5,Exo_endo_phos,LTD,Metallophos,PKD
YYD2_k127_442106_4	391625.PPSIR1_42054	8.82e-18	98.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Exo_endo_phos,HemolysinCabind,LTD
YYD2_k127_442106_3	880073.Calab_2400	6.168e-22	110.0	2E2T1@1|root,32XVB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_442106_1	880073.Calab_2402	1.167e-89	329.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_442106_7	1283299.AUKG01000001_gene1354	0.0001244	53.0	COG3391@1|root,COG3391@2|Bacteria,2GWAV@201174|Actinobacteria,4CRHS@84995|Rubrobacteria	84995|Rubrobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD2_k127_4423443_0	329726.AM1_2415	9.937e-76	262.0	COG0120@1|root,COG0120@2|Bacteria,1G2DW@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.rpiA	Rib_5-P_isom_A
YYD2_k127_4423443_1	195250.CM001776_gene471	2.903e-53	203.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1H0VR@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YYD2_k127_4423443_2	518766.Rmar_1151	0.0005338	52.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1076	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Autotransporter,DUF1929,Glyoxal_oxid_N,PA14
YYD2_k127_4447914_0	645991.Sgly_2480	6.592e-250	789.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YYD2_k127_4447914_7	795359.TOPB45_0364	2.604e-23	114.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	wzi	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi,PAP2
YYD2_k127_4447914_1	1380390.JIAT01000014_gene6174	6.529e-99	333.0	COG0673@1|root,COG0673@2|Bacteria,2HPZE@201174|Actinobacteria,4CREW@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YYD2_k127_4447914_2	1382356.JQMP01000001_gene1020	4.522e-78	281.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YYD2_k127_4447914_3	880072.Desac_0827	9.763e-69	255.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43DC7@68525|delta/epsilon subdivisions,2X8I7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YYD2_k127_4447914_5	1121918.ARWE01000001_gene1082	2.772e-56	215.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD2_k127_4447914_4	665571.STHERM_c09340	6.599e-61	219.0	COG1191@1|root,COG1191@2|Bacteria,2J5RA@203691|Spirochaetes	203691|Spirochaetes	K	Belongs to the sigma-70 factor family	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
YYD2_k127_4447914_6	635013.TherJR_1520	2.309e-50	194.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,26151@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
YYD2_k127_4464594_0	1161401.ASJA01000003_gene2857	5.04e-75	270.0	COG1680@1|root,COG1680@2|Bacteria,1QJH7@1224|Proteobacteria,2VFCQ@28211|Alphaproteobacteria,44130@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD2_k127_4465250_6	1380390.JIAT01000010_gene4797	7.796e-09	57.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_4465250_2	42256.RradSPS_2676	5.809e-74	264.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CP61@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YYD2_k127_4465250_3	1380394.JADL01000003_gene5164	1.404e-64	235.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
YYD2_k127_4465250_5	448385.sce5846	5.571e-33	144.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
YYD2_k127_4465250_4	1313421.JHBV01000043_gene3152	8.111e-39	164.0	28PN7@1|root,2ZCB2@2|Bacteria,4NJSS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4465250_1	204669.Acid345_3484	3.889e-116	388.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD2_k127_4465250_0	459349.CLOAM0442	9.847e-172	595.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
YYD2_k127_4465250_7	207954.MED92_04552	2.438e-06	49.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YYD2_k127_4465250_8	1382303.JPOM01000001_gene1125	3.746e-05	53.0	COG0810@1|root,COG0810@2|Bacteria,1RI3K@1224|Proteobacteria,2UA6S@28211|Alphaproteobacteria,2KGR4@204458|Caulobacterales	204458|Caulobacterales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD2_k127_4468863_1	1144275.COCOR_02607	4.214e-77	265.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2YUBB@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YYD2_k127_4468863_0	290397.Adeh_4004	4.933e-111	369.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
YYD2_k127_4468863_2	404589.Anae109_0419	6.151e-14	72.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD2_k127_4472655_5	518766.Rmar_0721	7.498e-08	65.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4472655_0	879212.DespoDRAFT_00577	4.663e-128	426.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria,2MHP9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
YYD2_k127_4472655_4	1123355.JHYO01000005_gene827	3.922e-25	117.0	COG0664@1|root,COG0664@2|Bacteria,1QERK@1224|Proteobacteria,2UGJU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
YYD2_k127_4472655_1	1278073.MYSTI_06647	2.762e-108	357.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,42ZGE@68525|delta/epsilon subdivisions,2WUVC@28221|Deltaproteobacteria,2YW9A@29|Myxococcales	28221|Deltaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
YYD2_k127_4472655_3	246197.MXAN_5034	1.009e-50	201.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2YUZA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
YYD2_k127_4472655_2	1121422.AUMW01000018_gene1867	1.27e-51	189.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,260VA@186807|Peptococcaceae	186801|Clostridia	KT	PFAM Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_9,PrpR_N,Sigma54_activat
YYD2_k127_4480835_2	935948.KE386495_gene1642	4.475e-55	198.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,42G9G@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YYD2_k127_4480835_3	880073.Calab_2162	1.939e-48	183.0	COG1428@1|root,COG1428@2|Bacteria,2NR23@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
YYD2_k127_4480835_0	1031288.AXAA01000007_gene906	1.467e-74	256.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia,36DNP@31979|Clostridiaceae	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
YYD2_k127_4480835_1	880073.Calab_0822	2.14e-68	242.0	COG1435@1|root,COG1435@2|Bacteria,2NP88@2323|unclassified Bacteria	2|Bacteria	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
YYD2_k127_4482451_1	1379698.RBG1_1C00001G0356	3.565e-73	273.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
YYD2_k127_4482451_0	861299.J421_3119	5.927e-94	333.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_4482451_2	59374.Fisuc_0695	6.194e-63	226.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YYD2_k127_4482451_4	429009.Adeg_1279	2.267e-20	104.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,42H28@68295|Thermoanaerobacterales	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YYD2_k127_4482451_3	743299.Acife_2731	5.403e-48	177.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,2NBQ5@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YYD2_k127_4482451_5	1120985.AUMI01000015_gene1458	2.734e-11	65.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H2XI@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
YYD2_k127_4495274_0	266117.Rxyl_2923	3.541e-92	312.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4CQPH@84995|Rubrobacteria	84995|Rubrobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
YYD2_k127_4495274_1	1121403.AUCV01000012_gene4113	1.643e-85	291.0	COG0623@1|root,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD2_k127_454538_4	477974.Daud_1317	7.433e-26	113.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,261KK@186807|Peptococcaceae	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD2_k127_454538_1	561175.KB894099_gene4933	6.442e-48	190.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4EIP6@85012|Streptosporangiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
YYD2_k127_454538_7	1125863.JAFN01000001_gene754	0.0002705	54.0	COG0457@1|root,COG0457@2|Bacteria,1NPUK@1224|Proteobacteria,42XSW@68525|delta/epsilon subdivisions,2WTHP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_454538_5	1235797.C816_02995	3.251e-25	116.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,2N69F@216572|Oscillospiraceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD2_k127_454538_3	391625.PPSIR1_12168	7.028e-43	165.0	2AB1F@1|root,310F3@2|Bacteria,1R7ZR@1224|Proteobacteria,43579@68525|delta/epsilon subdivisions,2WZI8@28221|Deltaproteobacteria,2Z27G@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
YYD2_k127_454538_2	391625.PPSIR1_02456	1.507e-44	171.0	2DB7W@1|root,2Z7P1@2|Bacteria,1N65F@1224|Proteobacteria,434RW@68525|delta/epsilon subdivisions,2X8ZY@28221|Deltaproteobacteria,2Z17U@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
YYD2_k127_454538_0	483219.LILAB_14785	1.393e-118	390.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,43B0A@68525|delta/epsilon subdivisions,2X6EE@28221|Deltaproteobacteria,2YUMP@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	leuB2	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD2_k127_454538_8	1121930.AQXG01000007_gene490	0.0003061	52.0	COG1649@1|root,COG4254@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4254@2|Bacteria,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1IU8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_454538_6	1265505.ATUG01000002_gene1898	2.599e-23	112.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
YYD2_k127_4567233_2	1423144.Gal_02777	5.263e-07	51.0	COG1999@1|root,COG1999@2|Bacteria,1MZAW@1224|Proteobacteria,2U1D6@28211|Alphaproteobacteria,34GD9@302485|Phaeobacter	28211|Alphaproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YYD2_k127_4567233_0	1116472.MGMO_138c00290	1.069e-128	424.0	COG1858@1|root,COG1999@1|root,COG1858@2|Bacteria,COG1999@2|Bacteria,1MV70@1224|Proteobacteria,1RRZM@1236|Gammaproteobacteria,1XH02@135618|Methylococcales	135618|Methylococcales	C	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,SCO1-SenC
YYD2_k127_4567233_1	1089553.Tph_c01250	1.685e-07	61.0	COG3222@1|root,COG3222@2|Bacteria,1V0BV@1239|Firmicutes	1239|Firmicutes	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064
YYD2_k127_4571450_5	9544.ENSMMUP00000019291	0.0005328	49.0	KOG3544@1|root,KOG3544@2759|Eukaryota,38CJN@33154|Opisthokonta,3BAFZ@33208|Metazoa,3CSDK@33213|Bilateria,485KV@7711|Chordata,491AC@7742|Vertebrata,3J8PF@40674|Mammalia,35MWU@314146|Euarchontoglires,4M5ND@9443|Primates,35YWX@314294|Cercopithecoidea	33208|Metazoa	W	Collagen type VII alpha 1	COL7A1	GO:0001704,GO:0001706,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005581,GO:0005590,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005793,GO:0005798,GO:0006810,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006996,GO:0007275,GO:0007369,GO:0007492,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009888,GO:0009987,GO:0012505,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0022607,GO:0030020,GO:0030134,GO:0030135,GO:0030154,GO:0030198,GO:0030934,GO:0031012,GO:0031090,GO:0031410,GO:0031974,GO:0031982,GO:0032501,GO:0032502,GO:0032991,GO:0033116,GO:0035987,GO:0042802,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048598,GO:0048646,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0061024,GO:0062023,GO:0065003,GO:0070013,GO:0071840,GO:0090114,GO:0097708,GO:0098588,GO:0098644,GO:0098648,GO:0098652,GO:0099080	-	ko:K16628	ko04974,map04974	-	-	-	ko00000,ko00001	-	-	-	Collagen,Kunitz_BPTI,VWA,fn3
YYD2_k127_4571450_0	862908.BMS_0702	2.52e-138	454.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
YYD2_k127_4571450_3	1123073.KB899242_gene962	1.386e-25	114.0	COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,1SD4H@1236|Gammaproteobacteria,1X7SY@135614|Xanthomonadales	135614|Xanthomonadales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
YYD2_k127_4571450_1	880073.Calab_1130	3.021e-87	300.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
YYD2_k127_4571450_2	880073.Calab_1131	9.123e-49	187.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_1131|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4571450_4	1380394.JADL01000004_gene6095	1.469e-13	70.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2U2JX@28211|Alphaproteobacteria,2JRBY@204441|Rhodospirillales	204441|Rhodospirillales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_458012_1	861299.J421_1876	2.488e-58	205.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
YYD2_k127_458012_0	296591.Bpro_3196	2.95e-138	448.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,4ADVR@80864|Comamonadaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
YYD2_k127_458012_2	204669.Acid345_0913	1.357e-30	140.0	COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4595435_2	1047013.AQSP01000115_gene361	5.444e-108	383.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_4595435_3	290397.Adeh_0625	2.795e-80	289.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,42PS3@68525|delta/epsilon subdivisions,2X7MQ@28221|Deltaproteobacteria,2YVCB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_8
YYD2_k127_4595435_1	204669.Acid345_1390	1.846e-146	473.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YYD2_k127_4595435_0	204669.Acid345_1391	1.855e-157	502.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD2_k127_4597307_1	1382359.JIAL01000001_gene1597	1.212e-67	246.0	COG1194@1|root,COG1194@2|Bacteria,3Y50Y@57723|Acidobacteria,2JHYP@204432|Acidobacteriia	204432|Acidobacteriia	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD2_k127_4597307_6	518766.Rmar_0609	2.158e-09	67.0	2FFT5@1|root,347QA@2|Bacteria,4P5W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
YYD2_k127_4597307_2	742817.HMPREF9449_01252	6.09e-49	184.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
YYD2_k127_4597307_4	497964.CfE428DRAFT_6228	1.748e-29	131.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	2|Bacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
YYD2_k127_4597307_0	290397.Adeh_0688	4.592e-112	388.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJU@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_4597307_3	997346.HMPREF9374_2476	7.052e-32	141.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,27AWT@186824|Thermoactinomycetaceae	91061|Bacilli	T	PAS domain	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
YYD2_k127_4597307_5	661478.OP10G_3487	7.205e-22	106.0	COG0745@1|root,COG0745@2|Bacteria	661478.OP10G_3487|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
YYD2_k127_4597307_7	760192.Halhy_6784	0.0008371	48.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1IQ66@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YYD2_k127_4613043_0	1210046.B277_07800	5.97e-23	109.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4FF65@85021|Intrasporangiaceae	201174|Actinobacteria	EI	Phospholipid biosynthesis protein	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
YYD2_k127_4613043_1	1123024.AUII01000005_gene2400	2.017e-15	83.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4DZAH@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM glycine oxidase ThiO	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
YYD2_k127_4622222_7	459349.CLOAM1690	0.0002198	55.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
YYD2_k127_4622222_5	679191.HMPREF9018_0242	4.092e-38	165.0	COG1361@1|root,COG1361@2|Bacteria,4PNRN@976|Bacteroidetes,2G0WE@200643|Bacteroidia	976|Bacteroidetes	M	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
YYD2_k127_4622222_3	518766.Rmar_0269	2.071e-73	256.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1FK1T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YYD2_k127_4622222_4	518766.Rmar_0268	3.105e-47	178.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1FK4G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YYD2_k127_4622222_1	926550.CLDAP_31240	6.713e-94	327.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD2_k127_4622222_2	696369.KI912183_gene1429	2.18e-75	270.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,260PT@186807|Peptococcaceae	186801|Clostridia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD2_k127_4622222_0	204669.Acid345_4761	8.425e-107	364.0	COG0312@1|root,COG0312@2|Bacteria,3Y2TY@57723|Acidobacteria,2JI8B@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD2_k127_4622222_6	1121920.AUAU01000006_gene258	1.052e-27	115.0	COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria	57723|Acidobacteria	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
YYD2_k127_4626951_0	497321.C664_12095	3.928e-122	397.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KV40@206389|Rhodocyclales	206389|Rhodocyclales	P	COG1613 ABC-type sulfate transport system, periplasmic component	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
YYD2_k127_4626951_1	671143.DAMO_1034	6.096e-98	329.0	COG0175@1|root,COG0175@2|Bacteria,2NPHM@2323|unclassified Bacteria	2|Bacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25	ko:K00366,ko:K00390,ko:K00860	ko00230,ko00910,ko00920,ko01100,ko01120,map00230,map00910,map00920,map01100,map01120	M00176,M00531	R00509,R00790,R02021,R04928	RC00002,RC00007,RC00078,RC00176,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YYD2_k127_4626951_2	123214.PERMA_0517	1.231e-13	80.0	COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,2G51R@200783|Aquificae	200783|Aquificae	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,PAPS_reduct,ThiS,TusA
YYD2_k127_4650711_0	562970.Btus_3284	1.273e-58	218.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,27876@186823|Alicyclobacillaceae	91061|Bacilli	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_4650711_1	497964.CfE428DRAFT_3893	5.726e-40	158.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD2_k127_4650711_3	644282.Deba_0755	1.05e-31	132.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
YYD2_k127_4650711_2	743721.Psesu_0771	6.21e-33	135.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1X6GJ@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YYD2_k127_4653196_0	717605.Theco_0340	7.556e-22	101.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_4743376_3	1521187.JPIM01000022_gene635	7.768e-05	57.0	COG1002@1|root,COG1002@2|Bacteria,2G7X3@200795|Chloroflexi,37694@32061|Chloroflexia	32061|Chloroflexia	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
YYD2_k127_4743376_0	1132509.C447_02652	6.442e-44	185.0	arCOG02636@1|root,arCOG04814@1|root,arCOG08946@1|root,arCOG02636@2157|Archaea,arCOG04814@2157|Archaea,arCOG08946@2157|Archaea,2XUQ7@28890|Euryarchaeota,23SFJ@183963|Halobacteria	183963|Halobacteria	V	COG1002 Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
YYD2_k127_4743376_2	880073.Calab_2777	8.476e-08	62.0	COG1361@1|root,COG2356@1|root,COG1361@2|Bacteria,COG2356@2|Bacteria,2NQUF@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease I	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,Fn3-like,LTD
YYD2_k127_4743376_1	1232437.KL662018_gene599	7.546e-35	135.0	COG0596@1|root,COG0596@2|Bacteria,1NEZY@1224|Proteobacteria,42WGF@68525|delta/epsilon subdivisions,2WSB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4750305_2	926566.Terro_0790	2.342e-31	132.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria,2JNIT@204432|Acidobacteriia	204432|Acidobacteriia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YYD2_k127_4750305_0	1192034.CAP_1695	8.14e-126	422.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_4750305_1	485913.Krac_8960	2.952e-70	246.0	COG0500@1|root,COG2226@2|Bacteria,2G6R0@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD2_k127_4755563_1	1122179.KB890480_gene3104	3.538e-15	87.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD2_k127_4755563_0	644966.Tmar_1010	1.083e-101	341.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WCSG@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
YYD2_k127_4804298_1	243232.MJ_0960	1.825e-76	264.0	COG0176@1|root,arCOG05061@2157|Archaea,2XTET@28890|Euryarchaeota,23Q23@183939|Methanococci	183939|Methanococci	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YYD2_k127_4804298_2	945713.IALB_1484	5.997e-76	273.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_4804298_0	477974.Daud_1634	9.66e-136	456.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YYD2_k127_4804298_3	1094715.CM001373_gene3313	2.682e-60	231.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD2_k127_4831489_0	1378168.N510_00620	3.442e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes	1239|Firmicutes	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_4831489_1	697284.ERIC2_c31020	0.0001781	50.0	2DS5W@1|root,33EPQ@2|Bacteria,1VMYK@1239|Firmicutes,4HSD8@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4840130_0	459349.CLOAM0871	1.325e-80	291.0	COG2843@1|root,COG3291@1|root,COG2843@2|Bacteria,COG3291@2|Bacteria,2NPJI@2323|unclassified Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap,PKD,Peptidase_M15_4
YYD2_k127_4840130_1	1379698.RBG1_1C00001G1437	4.197e-18	86.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YYD2_k127_4845976_10	1968.JOEV01000013_gene855	6.839e-52	197.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
YYD2_k127_4845976_11	555088.DealDRAFT_2711	1.415e-36	150.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,42K2Z@68298|Syntrophomonadaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YYD2_k127_4845976_13	1229172.JQFA01000004_gene345	8.07e-28	130.0	COG0169@1|root,COG0169@2|Bacteria,1G0CS@1117|Cyanobacteria,1H8SN@1150|Oscillatoriales	1117|Cyanobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
YYD2_k127_4845976_14	243230.DR_1389	3.19e-27	120.0	COG1040@1|root,COG1040@2|Bacteria,1WKB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YYD2_k127_4845976_1	1379698.RBG1_1C00001G0983	5.613e-152	495.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
YYD2_k127_4845976_15	1121430.JMLG01000002_gene985	1.57e-26	117.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,262DA@186807|Peptococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YYD2_k127_4845976_12	240015.ACP_2746	5.214e-32	126.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YYD2_k127_4845976_3	706587.Desti_3839	2.765e-114	376.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MQPY@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF987.Gmet_1360	Ldh_1_C,Ldh_1_N
YYD2_k127_4845976_9	471854.Dfer_5048	8.328e-56	205.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YYD2_k127_4845976_0	697284.ERIC2_c39010	4.839e-210	675.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YYD2_k127_4845976_7	478741.JAFS01000001_gene1890	1.688e-77	273.0	COG2877@1|root,COG2877@2|Bacteria,46SMZ@74201|Verrucomicrobia,37GGF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
YYD2_k127_4845976_8	945713.IALB_1894	1.046e-76	279.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria	2|Bacteria	M	arabinose-5-phosphate isomerase activity	kdsD	-	2.5.1.55,5.3.1.13	ko:K01627,ko:K03281,ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530,R03254	RC00435,RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	2.A.49	-	iAF987.Gmet_1278	CBS,SIS
YYD2_k127_4845976_19	984262.SGRA_1775	7.706e-10	70.0	COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
YYD2_k127_4845976_5	59374.Fisuc_1240	2.569e-91	308.0	COG1137@1|root,COG1137@2|Bacteria	2|Bacteria	S	lipopolysaccharide-transporting ATPase activity	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
YYD2_k127_4845976_4	1379270.AUXF01000006_gene272	1.769e-103	355.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YYD2_k127_4845976_16	484770.UFO1_4086	9.05e-21	99.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4H43Y@909932|Negativicutes	909932|Negativicutes	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
YYD2_k127_4845976_6	861299.J421_3121	1.712e-88	302.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
YYD2_k127_4845976_18	1122947.FR7_0506	1.152e-11	70.0	COG2893@1|root,COG2893@2|Bacteria,1VB2D@1239|Firmicutes,4H4Z8@909932|Negativicutes	909932|Negativicutes	G	PTS system, mannose fructose sorbose family, IIA subunit	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
YYD2_k127_4845976_17	390989.JOEG01000008_gene1283	8.618e-19	96.0	COG3444@1|root,COG3444@2|Bacteria,2GR9K@201174|Actinobacteria	201174|Actinobacteria	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02745,ko:K02793,ko:K02794	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277	R02630,R08366	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.4	-	-	EIIA-man,PTSIIB_sorb
YYD2_k127_4845976_2	880073.Calab_2422	7.894e-125	424.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
YYD2_k127_4847404_0	1499967.BAYZ01000195_gene3087	1.698e-121	407.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
YYD2_k127_4847404_3	113355.CM001775_gene3987	1.007e-26	115.0	COG0494@1|root,COG0494@2|Bacteria,1G1E4@1117|Cyanobacteria	1117|Cyanobacteria	L	mutator MutT protein	mutT	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX_4
YYD2_k127_4847404_2	330214.NIDE0722	5.246e-33	142.0	COG1018@1|root,COG1018@2|Bacteria	330214.NIDE0722|-	C	nitric oxide dioxygenase activity	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	-
YYD2_k127_4847404_1	379066.GAU_2637	2.862e-78	271.0	COG0603@1|root,COG0603@2|Bacteria,1ZT7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
YYD2_k127_4847404_4	1150469.RSPPHO_01086	9.085e-08	64.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,2JPK3@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YYD2_k127_4854138_4	1209072.ALBT01000023_gene4089	1.183e-21	111.0	COG1807@1|root,COG1807@2|Bacteria,1QSVX@1224|Proteobacteria,1RWGI@1236|Gammaproteobacteria,1FIC7@10|Cellvibrio	1236|Gammaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_4854138_5	1284352.AOIG01000018_gene4411	1.78e-21	109.0	COG4346@1|root,COG4346@2|Bacteria,1TSHX@1239|Firmicutes,4ISHD@91061|Bacilli,26SCF@186822|Paenibacillaceae	91061|Bacilli	O	Glycosyl transferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	F5_F8_type_C,GT87,PMT,PMT_2,PMT_4TMC
YYD2_k127_4854138_3	631454.N177_3529	7.742e-24	116.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2U3WV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YYD2_k127_4854138_1	237368.SCABRO_03725	2.453e-165	527.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
YYD2_k127_4854138_0	237368.SCABRO_03724	2.665e-174	572.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
YYD2_k127_4854138_2	247490.KSU1_B0225	1.708e-87	293.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1b
YYD2_k127_4854430_1	1150864.MILUP08_42631	0.0007773	51.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4DCV9@85008|Micromonosporales	201174|Actinobacteria	O	Subtilase family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
YYD2_k127_4854430_0	234267.Acid_3454	3.033e-45	186.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	57723|Acidobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
YYD2_k127_4862611_8	795359.TOPB45_1143	1.8e-11	65.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YYD2_k127_4862611_4	572477.Alvin_0777	5.211e-69	243.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
YYD2_k127_4862611_9	87626.PTD2_17885	1.821e-05	46.0	2DR6A@1|root,33ACN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4862611_7	1415779.JOMH01000001_gene1853	2.1e-19	98.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1X6IC@135614|Xanthomonadales	135614|Xanthomonadales	K	MerR family transcriptional regulator	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
YYD2_k127_4862611_3	1234364.AMSF01000080_gene3055	8.015e-79	283.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1X2XQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YYD2_k127_4862611_6	867903.ThesuDRAFT_00140	9.904e-33	136.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WCMQ@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YYD2_k127_4862611_0	349161.Dred_1160	2.233e-120	407.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YYD2_k127_4862611_2	1121422.AUMW01000001_gene2454	1.449e-105	358.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
YYD2_k127_4862611_5	644282.Deba_0825	1.153e-61	226.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YYD2_k127_4862611_1	517417.Cpar_1905	1.989e-107	368.0	COG0323@1|root,COG0323@2|Bacteria,1FDFS@1090|Chlorobi	1090|Chlorobi	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YYD2_k127_4876945_2	1122218.KB893653_gene765	6.371e-11	72.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,1JQP8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YYD2_k127_4876945_3	1121904.ARBP01000018_gene2603	1.104e-07	57.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YYD2_k127_4876945_1	1307759.JOMJ01000003_gene786	4.654e-39	159.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M7UX@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YYD2_k127_4876945_0	909663.KI867150_gene1384	4.397e-74	258.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MR4I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YYD2_k127_4896925_1	857293.CAAU_1205	1.5e-91	307.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,36E2S@31979|Clostridiaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD2_k127_4896925_9	861299.J421_3580	1.838e-11	64.0	COG0257@1|root,COG0257@2|Bacteria,1ZVAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YYD2_k127_4896925_4	525903.Taci_1158	1.4e-49	179.0	COG0099@1|root,COG0099@2|Bacteria,3TAYV@508458|Synergistetes	508458|Synergistetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YYD2_k127_4896925_5	935948.KE386495_gene1486	3.146e-48	175.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,42G9M@68295|Thermoanaerobacterales	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YYD2_k127_4896925_3	1121430.JMLG01000033_gene1357	6.957e-78	268.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,260U9@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YYD2_k127_4896925_0	1379698.RBG1_1C00001G1568	1.24e-105	353.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YYD2_k127_4896925_6	1111454.HMPREF1250_0439	1.353e-31	134.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4H4TR@909932|Negativicutes	909932|Negativicutes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YYD2_k127_4896925_7	304371.MCP_0420	7.437e-31	132.0	arCOG01637@1|root,arCOG01637@2157|Archaea,2Y1E8@28890|Euryarchaeota,2NA48@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD2_k127_4896925_8	1340493.JNIF01000003_gene4645	5.546e-25	118.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
YYD2_k127_4896925_2	479434.Sthe_0481	6.318e-78	272.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi,27Y22@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
YYD2_k127_4906278_0	1519464.HY22_06250	4.988e-34	150.0	COG1629@1|root,COG4771@2|Bacteria,1FEPH@1090|Chlorobi	1090|Chlorobi	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
YYD2_k127_4911245_8	414684.RC1_3268	8.385e-06	50.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2JPTX@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YYD2_k127_4911245_7	1210884.HG799462_gene9284	6.443e-43	171.0	COG0584@1|root,COG0584@2|Bacteria,2IYVE@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD_2
YYD2_k127_4911245_6	1157490.EL26_06945	9.638e-52	204.0	COG0312@1|root,COG0312@2|Bacteria,1V3G5@1239|Firmicutes	1239|Firmicutes	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD2_k127_4911245_3	1157490.EL26_06940	1.313e-84	305.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,4HA0D@91061|Bacilli	91061|Bacilli	S	Zn-dependent proteases and their inactivated homologs	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD2_k127_4911245_5	861299.J421_5582	7.047e-64	241.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
YYD2_k127_4911245_4	1254432.SCE1572_45390	1.992e-78	286.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YYD2_k127_4911245_2	1123388.AQWU01000067_gene652	8.817e-108	364.0	COG0604@1|root,COG0604@2|Bacteria,1WI1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_4911245_1	1379698.RBG1_1C00001G0806	4.174e-118	385.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
YYD2_k127_4911245_0	1379698.RBG1_1C00001G0805	1.783e-182	584.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD2_k127_4914994_1	861299.J421_3894	1.531e-28	121.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD2_k127_4914994_0	861299.J421_3893	7.847e-132	434.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YYD2_k127_4918571_4	1121920.AUAU01000006_gene301	4.148e-09	57.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4918571_2	574376.BAMA_04195	1.137e-61	224.0	COG2162@1|root,COG2162@2|Bacteria,1VA4Y@1239|Firmicutes,4HKYP@91061|Bacilli,1ZGW6@1386|Bacillus	91061|Bacilli	Q	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
YYD2_k127_4918571_3	368407.Memar_0639	4.224e-13	83.0	COG3291@1|root,arCOG02527@1|root,arCOG02542@1|root,arCOG02508@2157|Archaea,arCOG02527@2157|Archaea,arCOG02542@2157|Archaea,2XYVG@28890|Euryarchaeota	28890|Euryarchaeota	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
YYD2_k127_4918571_1	1095769.CAHF01000005_gene1545	6.699e-66	237.0	COG1018@1|root,COG1018@2|Bacteria,1RAS4@1224|Proteobacteria,2VQ3I@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
YYD2_k127_4918571_0	370438.PTH_2214	2.221e-123	413.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
YYD2_k127_4921134_1	1123368.AUIS01000003_gene1617	1.161e-91	325.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,2NC5I@225057|Acidithiobacillales	225057|Acidithiobacillales	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
YYD2_k127_4921134_4	330214.NIDE3418	3.509e-57	214.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_4921134_0	1379698.RBG1_1C00001G1029	1.229e-147	487.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YYD2_k127_4921134_3	515635.Dtur_1285	2.182e-59	225.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
YYD2_k127_4921134_2	439235.Dalk_1044	3.464e-61	221.0	290BN@1|root,2ZN16@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4921134_5	1144275.COCOR_05757	7.137e-06	57.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YZ03@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,PKD
YYD2_k127_4923095_5	479433.Caci_5435	5.938e-06	59.0	COG3832@1|root,COG3832@2|Bacteria,2IFRJ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD2_k127_4923095_3	653733.Selin_1334	3.346e-22	100.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
YYD2_k127_4923095_2	55529.EKX50984	1.333e-36	150.0	KOG0266@1|root,KOG0274@1|root,KOG0266@2759|Eukaryota,KOG0274@2759|Eukaryota	2759|Eukaryota	M	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	-	GO:0000003,GO:0000151,GO:0000746,GO:0000747,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006508,GO:0006511,GO:0006807,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0019005,GO:0019538,GO:0019941,GO:0019953,GO:0022414,GO:0030163,GO:0030674,GO:0031145,GO:0031461,GO:0032991,GO:0043161,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0044703,GO:0044764,GO:0050789,GO:0050794,GO:0051603,GO:0051704,GO:0051726,GO:0060090,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234	-	ko:K03361,ko:K22071	ko04111,ko04120,map04111,map04120	M00407	-	-	ko00000,ko00001,ko00002,ko03029,ko04121	-	-	-	F-box-like,HET,NACHT,WD40
YYD2_k127_4923095_0	926569.ANT_17720	3.855e-158	509.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YYD2_k127_4923095_1	690850.Desaf_1287	1.094e-60	225.0	COG1271@1|root,COG1271@2|Bacteria,1QXQF@1224|Proteobacteria,42NKJ@68525|delta/epsilon subdivisions,2WKHM@28221|Deltaproteobacteria,2M95S@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidase subunit	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	-
YYD2_k127_4923095_4	1168034.FH5T_03790	3.679e-18	86.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,4NZYJ@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD2_k127_4946371_2	1123320.KB889607_gene9508	1.161e-05	55.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Polysacc_deac_1
YYD2_k127_4946371_0	479434.Sthe_1363	1.102e-50	189.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
YYD2_k127_4946371_1	861299.J421_1222	5.599e-27	113.0	COG1393@1|root,COG1393@2|Bacteria,1ZTUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
YYD2_k127_49549_1	861299.J421_3860	2.047e-40	154.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
YYD2_k127_49549_0	1379698.RBG1_1C00001G1816	5.324e-70	260.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
YYD2_k127_4955639_0	1210884.HG799466_gene12558	1.939e-291	917.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YYD2_k127_4957965_0	448385.sce6263	1.594e-100	343.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
YYD2_k127_4957965_1	309807.SRU_0977	3.627e-68	248.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_4963250_3	1379698.RBG1_1C00001G0436	4.824e-18	86.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD2_k127_4963250_2	1121866.AUGK01000004_gene246	1.015e-20	99.0	COG0779@1|root,COG0779@2|Bacteria,2HUVT@201174|Actinobacteria,4CVTM@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
YYD2_k127_4963250_0	1379698.RBG1_1C00001G1152	8.497e-110	375.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YYD2_k127_4963250_1	1379698.RBG1_1C00001G1153	1.672e-74	265.0	COG0532@1|root,COG0532@2|Bacteria,2NNRG@2323|unclassified Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
YYD2_k127_498338_1	927677.ALVU02000001_gene2236	2.047e-48	178.0	COG0477@1|root,COG0477@2|Bacteria,1G155@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_498338_0	1380393.JHVP01000003_gene1104	1.571e-158	527.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
YYD2_k127_498338_2	518766.Rmar_0433	1.218e-09	67.0	COG2353@1|root,COG2353@2|Bacteria,4PBAH@976|Bacteroidetes,1FK7G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YYD2_k127_4997113_0	935848.JAEN01000026_gene301	7.319e-06	59.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YYD2_k127_5000903_3	679192.HMPREF9013_0797	5.293e-11	64.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,3VPDK@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score 8.87	aroF	-	-	-	-	-	-	-	-	-	-	-	DAHP_synth_1
YYD2_k127_5000903_1	243231.GSU1870	3.247e-33	143.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria,43W33@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD2_k127_5000903_0	459349.CLOAM0176	1.197e-33	149.0	COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YYD2_k127_5000903_2	309798.COPRO5265_1266	2.536e-17	90.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YYD2_k127_506678_0	926560.KE387023_gene3595	3.503e-50	194.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
YYD2_k127_5072986_0	324925.Ppha_0260	1.432e-62	237.0	COG5617@1|root,COG5617@2|Bacteria,1FDV6@1090|Chlorobi	1090|Chlorobi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
YYD2_k127_5083066_1	880073.Calab_2084	2.288e-15	78.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,FlgD_ig,Peptidase_S74
YYD2_k127_5083066_0	644966.Tmar_0456	2.917e-19	93.0	COG1430@1|root,COG1430@2|Bacteria,1UQXC@1239|Firmicutes,258QC@186801|Clostridia,3WDN7@538999|Clostridiales incertae sedis	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
YYD2_k127_5083066_3	1384056.N787_06460	7.105e-08	62.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S3GT@1236|Gammaproteobacteria,1XC77@135614|Xanthomonadales	135614|Xanthomonadales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_5083066_2	240015.ACP_2689	3.314e-09	64.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y4M5@57723|Acidobacteria,2JP1D@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_5100013_1	459349.CLOAM0865	2.144e-33	135.0	29EG8@1|root,334DW@2|Bacteria,2NPTE@2323|unclassified Bacteria	2|Bacteria	S	Capsule biosynthesis CapC	capC	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
YYD2_k127_5100013_0	1047013.AQSP01000131_gene1824	3.28e-51	196.0	28JNG@1|root,2Z9ES@2|Bacteria,2NPDF@2323|unclassified Bacteria	2|Bacteria	-	-	pgsW	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5100818_2	1121931.AUHG01000010_gene433	1.265e-29	124.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,1I0ZQ@117743|Flavobacteriia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
YYD2_k127_5100818_1	344747.PM8797T_23676	8.514e-49	185.0	2ANS9@1|root,31DS7@2|Bacteria,2IZX5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5100818_0	1379698.RBG1_1C00001G0113	1.041e-60	220.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5120803_1	929712.KI912613_gene2446	6.337e-17	90.0	2DTFW@1|root,33K6G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
YYD2_k127_5120803_0	1123242.JH636434_gene4579	3.992e-118	385.0	COG0191@1|root,COG0191@2|Bacteria,2IWXE@203682|Planctomycetes	203682|Planctomycetes	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
YYD2_k127_5125236_1	391625.PPSIR1_36027	3.31e-06	54.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,42RXB@68525|delta/epsilon subdivisions,2WNXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
YYD2_k127_5125236_0	1121445.ATUZ01000020_gene2126	1.873e-11	69.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,42N56@68525|delta/epsilon subdivisions,2WITM@28221|Deltaproteobacteria,2MHBB@213115|Desulfovibrionales	28221|Deltaproteobacteria	KQ	sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,PAS,PAS_8,Sigma54_activat
YYD2_k127_5125435_2	379066.GAU_1512	4.607e-54	192.0	COG0151@1|root,COG0151@2|Bacteria,1ZSWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
YYD2_k127_5125435_0	1163617.SCD_n00855	0.0	1076.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YYD2_k127_5125435_1	502025.Hoch_0068	3.636e-56	221.0	COG3227@1|root,COG3227@2|Bacteria,1Q6DC@1224|Proteobacteria,432XR@68525|delta/epsilon subdivisions,2WYJ7@28221|Deltaproteobacteria,2Z34H@29|Myxococcales	28221|Deltaproteobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5125611_0	240015.ACP_2544	7.566e-147	473.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD2_k127_5125611_1	1121285.AUFK01000014_gene2872	3.992e-31	126.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia,3ZS1C@59732|Chryseobacterium	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YYD2_k127_5137441_0	321327.CYA_2836	4.778e-130	453.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1GYFK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD2_k127_5137918_6	667014.Thein_2154	8.164e-33	133.0	COG0223@1|root,COG0223@2|Bacteria,2GGW2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YYD2_k127_5137918_4	1089550.ATTH01000001_gene512	6.466e-44	181.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,4NEV7@976|Bacteroidetes,1FITV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
YYD2_k127_5137918_10	1121472.AQWN01000014_gene631	2.838e-12	78.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
YYD2_k127_5137918_2	537013.CLOSTMETH_02118	3.943e-51	191.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YYD2_k127_5137918_0	644966.Tmar_0957	8.196e-141	460.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WCDI@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
YYD2_k127_5137918_9	429009.Adeg_1416	5.302e-18	87.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
YYD2_k127_5137918_7	880073.Calab_2052	1.307e-27	114.0	COG1837@1|root,COG1837@2|Bacteria,2NPUP@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
YYD2_k127_5137918_8	309799.DICTH_1425	1.004e-23	109.0	COG0806@1|root,COG0806@2|Bacteria	2|Bacteria	J	ribosome binding	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
YYD2_k127_5137918_1	515635.Dtur_1534	1.763e-68	247.0	COG0336@1|root,COG0336@2|Bacteria	2|Bacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YYD2_k127_5137918_5	767817.Desgi_2740	3.109e-40	152.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YYD2_k127_5137918_3	264732.Moth_0976	1.469e-45	186.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,42FWD@68295|Thermoanaerobacterales	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
YYD2_k127_5149822_4	1380390.JIAT01000016_gene5509	1.995e-11	68.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CPNE@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YYD2_k127_5149822_2	945713.IALB_2183	1.116e-95	327.0	COG0686@1|root,COG0686@2|Bacteria	2|Bacteria	E	alanine dehydrogenase activity	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
YYD2_k127_5149822_0	1111069.TCCBUS3UF1_4090	1.687e-181	576.0	COG0427@1|root,COG0427@2|Bacteria,1WJIT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
YYD2_k127_5149822_1	1380394.JADL01000007_gene4450	7.438e-101	346.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,2JYB7@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
YYD2_k127_5149822_3	391008.Smal_3688	7.583e-87	303.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,1X3CG@135614|Xanthomonadales	135614|Xanthomonadales	S	N-acyl-L-amino acid amidohydrolase	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YYD2_k127_5151635_2	192875.XP_004348661.1	9.518e-32	142.0	COG2234@1|root,KOG2195@2759|Eukaryota	2759|Eukaryota	L	exopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD2_k127_5151635_1	243233.MCA1010	2.724e-34	133.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XFY6@135618|Methylococcales	135618|Methylococcales	S	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD2_k127_5151635_0	118163.Ple7327_4070	7.169e-68	254.0	COG0612@1|root,COG0612@2|Bacteria,1G3GH@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD2_k127_5152037_0	1173028.ANKO01000112_gene4786	9.709e-68	246.0	COG5379@1|root,COG5379@2|Bacteria,1GC1E@1117|Cyanobacteria,1HEN7@1150|Oscillatoriales	1117|Cyanobacteria	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
YYD2_k127_5152037_3	266117.Rxyl_0272	9.943e-14	84.0	COG1183@1|root,COG1183@2|Bacteria,2IC3M@201174|Actinobacteria	201174|Actinobacteria	I	phosphatidylcholine synthase	pcs	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YYD2_k127_5152037_4	234267.Acid_0751	0.0001694	54.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD2_k127_5152037_1	573370.DMR_08160	4.857e-49	197.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42RQD@68525|delta/epsilon subdivisions,2WNSR@28221|Deltaproteobacteria,2MG5H@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_5152037_2	1151126.AQYI01000007_gene1986	3.119e-38	157.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4FKVV@85023|Microbacteriaceae	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD2_k127_5152757_0	215803.DB30_5113	2.727e-99	344.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
YYD2_k127_5152757_1	1384054.N790_05820	1.882e-57	216.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1Q5AK@1224|Proteobacteria,1S19Z@1236|Gammaproteobacteria,1X5VR@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
YYD2_k127_5152757_2	471223.GWCH70_1493	1.688e-24	109.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1WHEI@129337|Geobacillus	91061|Bacilli	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YYD2_k127_5163117_1	1121920.AUAU01000012_gene2648	4.388e-79	274.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
YYD2_k127_5163117_0	945713.IALB_2426	4.532e-87	295.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4
YYD2_k127_5163117_2	1232437.KL662048_gene5081	8.094e-13	77.0	COG0509@1|root,COG0509@2|Bacteria,1NRFW@1224|Proteobacteria,42ZAN@68525|delta/epsilon subdivisions,2WUQI@28221|Deltaproteobacteria,2MMY2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
YYD2_k127_5163117_3	706587.Desti_3892	6.39e-11	71.0	COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
YYD2_k127_5167587_0	926550.CLDAP_34140	1.963e-50	192.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
YYD2_k127_5167587_1	926569.ANT_10740	1.433e-38	159.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
YYD2_k127_5167587_2	404589.Anae109_1332	8.715e-18	92.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
YYD2_k127_5180138_0	304371.MCP_1804	2.106e-149	483.0	COG1914@1|root,arCOG04531@2157|Archaea,2XU6H@28890|Euryarchaeota,2NASS@224756|Methanomicrobia	224756|Methanomicrobia	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
YYD2_k127_5180138_1	1379698.RBG1_1C00001G1240	4.777e-78	276.0	COG2239@1|root,COG2239@2|Bacteria,2NP79@2323|unclassified Bacteria	2|Bacteria	P	MgtE intracellular N domain	opuCA	-	3.6.3.32	ko:K02000,ko:K05847	ko02010,map02010	M00208,M00209	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	iSB619.SA_RS12845	ABC_tran,CBS,MgtE_N,PRC
YYD2_k127_5180138_2	42256.RradSPS_1156	4.353e-51	194.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_5180138_3	644282.Deba_1175	2.376e-10	66.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
YYD2_k127_5188312_5	987059.RBXJA2T_11723	1.857e-05	51.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KK0F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_5188312_1	247490.KSU1_C1550	2.291e-44	173.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	ideR	-	-	ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
YYD2_k127_5188312_0	404589.Anae109_2250	7.521e-175	576.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
YYD2_k127_5188312_3	1121920.AUAU01000014_gene2815	1.068e-32	132.0	COG0735@1|root,COG0735@2|Bacteria,3Y5IN@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YYD2_k127_5188312_2	215803.DB30_6652	1.253e-38	151.0	COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,430R4@68525|delta/epsilon subdivisions,2WW5G@28221|Deltaproteobacteria,2YY3X@29|Myxococcales	28221|Deltaproteobacteria	G	SIS domain	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS_2
YYD2_k127_5190026_2	1089550.ATTH01000001_gene1072	2.467e-06	50.0	COG1409@1|root,COG1572@1|root,COG4733@1|root,COG1409@2|Bacteria,COG1572@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4,3.4.21.96	ko:K01179,ko:K01361,ko:K13277,ko:K21449	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	GH5,GH9	-	Amidase_2,DUF1735,Glucosaminidase,Laminin_G_3
YYD2_k127_5190026_1	379066.GAU_3840	4.629e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD2_k127_5190026_0	502025.Hoch_1577	1.397e-106	379.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD2_k127_5203393_0	1122223.KB890700_gene2026	6.815e-49	193.0	COG0438@1|root,COG0438@2|Bacteria,1WK9I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_5252559_0	1476583.DEIPH_ctg026orf0048	2.297e-12	71.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_16,Wzy_C
YYD2_k127_5252559_1	944560.HMPREF9058_1898	6.16e-09	68.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4D3WM@85005|Actinomycetales	201174|Actinobacteria	M	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
YYD2_k127_5259895_2	243231.GSU2269	1.285e-42	161.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YYD2_k127_5259895_1	671143.DAMO_1656	4.201e-105	355.0	COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria	2|Bacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
YYD2_k127_5259895_0	1379698.RBG1_1C00001G1211	2.887e-156	505.0	COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
YYD2_k127_5262318_1	365044.Pnap_1340	3.327e-34	140.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
YYD2_k127_5262318_2	1379270.AUXF01000003_gene3588	2.117e-26	117.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
YYD2_k127_5262318_0	935836.JAEL01000041_gene4722	1.39e-57	203.0	COG0179@1|root,COG0179@2|Bacteria,1TXPE@1239|Firmicutes,4I6Q6@91061|Bacilli,1ZME2@1386|Bacillus	91061|Bacilli	Q	Fumarylacetoacetase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase,FAA_hydrolase_N
YYD2_k127_527841_1	1124780.ANNU01000078_gene772	1.444e-21	102.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD2_k127_527841_0	926550.CLDAP_26800	2.423e-43	167.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD2_k127_5283577_0	1187851.A33M_3198	9.06e-118	386.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
YYD2_k127_5283577_1	1232410.KI421421_gene3273	2.276e-89	308.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2X5NK@28221|Deltaproteobacteria,43W2S@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
YYD2_k127_5290481_4	1224746.B932_0467	9.366e-07	51.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1MWF0@1224|Proteobacteria,2UA73@28211|Alphaproteobacteria,2JTPT@204441|Rhodospirillales	204441|Rhodospirillales	P	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
YYD2_k127_5290481_3	889378.Spiaf_0715	3.944e-55	200.0	COG0765@1|root,COG0765@2|Bacteria,2J5BG@203691|Spirochaetes	203691|Spirochaetes	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
YYD2_k127_5290481_2	498761.HM1_1263	9.735e-85	289.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028,ko:K10041	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
YYD2_k127_5290481_1	1267535.KB906767_gene1151	3.946e-295	920.0	COG1048@1|root,COG1048@2|Bacteria,3Y4NH@57723|Acidobacteria	57723|Acidobacteria	C	Aconitase family (aconitate hydratase)	-	-	-	-	-	-	-	-	-	-	-	-	Aconitase,Aconitase_C
YYD2_k127_5290481_0	1121468.AUBR01000064_gene947	1.329e-301	937.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24E00@186801|Clostridia,42FQ1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD2_k127_5296579_0	1379698.RBG1_1C00001G1661	5.938e-162	526.0	COG1239@1|root,COG1239@2|Bacteria,2NQQG@2323|unclassified Bacteria	2|Bacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
YYD2_k127_5296579_1	530564.Psta_1338	1.609e-12	79.0	29X2I@1|root,33MMI@2|Bacteria,2J1I2@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YYD2_k127_5323620_2	211586.SO_1925	1.163e-43	176.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,2Q9HX@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YYD2_k127_5323620_0	880073.Calab_1195	7.636e-240	794.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD2_k127_5323620_1	1121104.AQXH01000001_gene1413	1.815e-148	518.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD2_k127_5346668_0	459349.CLOAM0769	3.552e-60	222.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
YYD2_k127_5346668_1	459349.CLOAM0177	5.694e-11	68.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
YYD2_k127_5373566_0	1121875.KB907549_gene1886	5.061e-95	326.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1HYVR@117743|Flavobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
YYD2_k127_5373566_1	1185876.BN8_01300	2.956e-30	126.0	COG3631@1|root,COG3631@2|Bacteria,4NVWJ@976|Bacteroidetes,47WCU@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD2_k127_5374213_2	986075.CathTA2_2562	1.536e-56	203.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD2_k127_5374213_4	243090.RB10458	8.41e-25	107.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD2_k127_5374213_3	1304872.JAGC01000009_gene650	1.016e-50	195.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WPW4@28221|Deltaproteobacteria,2MCTH@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD2_k127_5374213_5	2880.D8LNY1	3.096e-09	69.0	2BFIX@1|root,2S176@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Chlam_PMP
YYD2_k127_5374213_1	240015.ACP_3311	4.716e-138	453.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
YYD2_k127_5374213_0	1007103.AFHW01000087_gene6321	3.919e-144	474.0	COG3508@1|root,COG3508@2|Bacteria,1UYZ0@1239|Firmicutes,4HCCC@91061|Bacilli,26V1U@186822|Paenibacillaceae	91061|Bacilli	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
YYD2_k127_5374213_7	269799.Gmet_3221	3.638e-05	56.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_5374213_6	639282.DEFDS_0275	2.099e-07	53.0	COG1729@1|root,COG1729@2|Bacteria,2GFHW@200930|Deferribacteres	200930|Deferribacteres	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
YYD2_k127_5376237_7	710111.FraQA3DRAFT_3216	7.842e-13	69.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
YYD2_k127_5376237_6	349741.Amuc_2132	8.009e-14	76.0	COG0375@1|root,COG0375@2|Bacteria,46WGA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
YYD2_k127_5376237_4	1408428.JNJP01000024_gene3775	2.364e-62	222.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2M883@213115|Desulfovibrionales	28221|Deltaproteobacteria	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
YYD2_k127_5376237_5	234267.Acid_1872	1.429e-23	107.0	COG1146@1|root,COG1146@2|Bacteria,3Y8V9@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	-
YYD2_k127_5376237_1	880073.Calab_0324	6.994e-150	481.0	COG0674@1|root,COG0674@2|Bacteria,2NNWT@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
YYD2_k127_5376237_0	880073.Calab_0325	3.631e-184	589.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,2NNMC@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porG	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00177,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,TPP_enzyme_C
YYD2_k127_5376237_2	1408444.JHYC01000027_gene493	1.125e-107	358.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1JCKN@118969|Legionellales	118969|Legionellales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
YYD2_k127_5376237_3	247490.KSU1_D0400	2.155e-90	307.0	COG2204@1|root,COG2204@2|Bacteria	247490.KSU1_D0400|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5376803_1	215803.DB30_7949	2.625e-223	706.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
YYD2_k127_5376803_0	1121920.AUAU01000023_gene2395	2.013e-231	751.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.3,4.2.1.33,4.2.1.35	ko:K01681,ko:K01703,ko:K01704,ko:K17749	ko00020,ko00290,ko00400,ko00630,ko00660,ko00720,ko00966,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00400,map00630,map00660,map00720,map00966,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00432,M00535,M00740	R01324,R01325,R01900,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170,R10501	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD2_k127_5376803_2	439235.Dalk_3860	0.0005024	51.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
YYD2_k127_5391266_2	1125863.JAFN01000001_gene531	2.581e-17	84.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
YYD2_k127_5391266_1	58123.JOFJ01000015_gene4404	4.784e-44	180.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria	201174|Actinobacteria	I	Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YYD2_k127_5391266_0	429009.Adeg_0438	3.525e-121	401.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,42F9F@68295|Thermoanaerobacterales	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
YYD2_k127_5397340_0	1128421.JAGA01000001_gene2075	1.444e-123	405.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-3	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YYD2_k127_5397340_1	518766.Rmar_1871	4.638e-61	220.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1FJBX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	LD-carboxypeptidase	ldcA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
YYD2_k127_5403720_1	680198.SCAB_65291	3.749e-06	59.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
YYD2_k127_5403720_0	530564.Psta_3518	5.832e-10	72.0	COG3832@1|root,COG3832@2|Bacteria,2J16I@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD2_k127_5407589_5	1349767.GJA_455	5.381e-09	67.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,4743P@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
YYD2_k127_5407589_1	338963.Pcar_3063	1.903e-86	297.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,43T66@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YYD2_k127_5407589_0	644966.Tmar_1263	6.346e-97	344.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YYD2_k127_5407589_2	945713.IALB_0544	4.148e-40	160.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YYD2_k127_5407589_3	546414.Deide_23390	1.311e-37	152.0	COG1192@1|root,COG1192@2|Bacteria,1WIIX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YYD2_k127_5407589_4	34506.g1113	4.715e-37	141.0	COG1048@1|root,KOG0453@2759|Eukaryota,38CNX@33154|Opisthokonta,3B95S@33208|Metazoa,3CSK2@33213|Bilateria,40BJU@6231|Nematoda,1KV47@119089|Chromadorea,40XVW@6236|Rhabditida	33208|Metazoa	CE	Aconitase C-terminal domain	ACO2	GO:0001889,GO:0003674,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006102,GO:0006950,GO:0007275,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0031974,GO:0032501,GO:0032502,GO:0035900,GO:0043167,GO:0043169,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0048513,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0061008,GO:0070013,GO:0071704,GO:0072350	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD2_k127_5417065_0	1120971.AUCA01000026_gene630	8.327e-114	378.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,277Y5@186823|Alicyclobacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YYD2_k127_5417065_1	215803.DB30_1735	5.531e-12	71.0	COG2010@1|root,COG2010@2|Bacteria,1Q37P@1224|Proteobacteria,438YG@68525|delta/epsilon subdivisions,2X9X4@28221|Deltaproteobacteria,2YY6N@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YYD2_k127_5430162_0	1123288.SOV_1c05850	6.627e-126	424.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4H3B3@909932|Negativicutes	909932|Negativicutes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
YYD2_k127_5430162_2	1329516.JPST01000012_gene160	8.939e-38	154.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,27C20@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glycine cleavage H-protein	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YYD2_k127_5430162_1	221360.RS9917_06175	4.202e-57	204.0	COG0404@1|root,COG0404@2|Bacteria,1G0GR@1117|Cyanobacteria,1GYU4@1129|Synechococcus	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YYD2_k127_5451697_1	234267.Acid_4597	1.588e-44	166.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD2_k127_5451697_0	1122917.KB899662_gene2150	2.5e-92	320.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,26RRS@186822|Paenibacillaceae	91061|Bacilli	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD2_k127_5451697_3	1089550.ATTH01000001_gene176	0.0002241	53.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1FK4U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
YYD2_k127_5451697_2	469382.Hbor_17010	5.569e-10	61.0	COG0451@1|root,arCOG01369@2157|Archaea,2Y7SY@28890|Euryarchaeota,23SBI@183963|Halobacteria	183963|Halobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD2_k127_5455551_0	1123278.KB893444_gene1718	4.871e-05	56.0	COG4447@1|root,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YYD2_k127_545838_1	880073.Calab_2467	3.674e-75	264.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
YYD2_k127_545838_0	1379698.RBG1_1C00001G1779	1.243e-127	419.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD2_k127_545838_2	1192034.CAP_1885	4.729e-39	150.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,2YW79@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YYD2_k127_545838_3	1297742.A176_02922	8.298e-19	87.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2YTTC@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YYD2_k127_5464081_1	237368.SCABRO_03474	6.895e-44	178.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD2_k127_5464081_0	96561.Dole_2158	1.926e-54	205.0	COG0583@1|root,COG1910@1|root,COG0583@2|Bacteria,COG1910@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MIF9@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD2_k127_5464081_2	880073.Calab_3487	1.587e-14	82.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6
YYD2_k127_5467274_0	1382306.JNIM01000001_gene1548	5.017e-94	328.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5468928_0	313612.L8106_08611	5.554e-60	226.0	COG0438@1|root,COG0438@2|Bacteria,1G0AQ@1117|Cyanobacteria,1HA76@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_5468928_1	766499.C357_23040	2.637e-26	121.0	COG0578@1|root,COG0578@2|Bacteria,1RKH8@1224|Proteobacteria,2UANY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO
YYD2_k127_5468928_2	929703.KE386491_gene2656	2.237e-10	65.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
YYD2_k127_5478817_4	1123279.ATUS01000001_gene622	4.43e-16	87.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1J4W1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2515 1-aminocyclopropane-1-carboxylate deaminase	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
YYD2_k127_5478817_1	1379698.RBG1_1C00001G0410	1.255e-76	269.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YYD2_k127_5478817_0	1125863.JAFN01000001_gene594	6.489e-78	267.0	COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,42VB4@68525|delta/epsilon subdivisions,2WS37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
YYD2_k127_5478817_3	1463820.JOGW01000021_gene210	1.963e-18	96.0	COG0463@1|root,COG0463@2|Bacteria,2I3W9@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_5478817_2	1278073.MYSTI_03345	2.253e-24	115.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_5482376_1	41431.PCC8801_3455	0.0002042	49.0	COG2192@1|root,COG2192@2|Bacteria,1GRBF@1117|Cyanobacteria,3KI6V@43988|Cyanothece	1117|Cyanobacteria	O	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5482376_0	1499967.BAYZ01000095_gene4126	2.542e-263	824.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YYD2_k127_5486113_0	378806.STAUR_4411	0.0	1323.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD2_k127_5487611_2	1121931.AUHG01000010_gene507	8.088e-31	127.0	2DEWP@1|root,2ZPJE@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD2_k127_5487611_0	1408254.T458_20775	4.944e-115	385.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YYD2_k127_5487611_1	1007103.AFHW01000032_gene2246	8.47e-91	303.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YYD2_k127_549414_0	1267535.KB906767_gene2550	2.855e-220	694.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YYD2_k127_5494558_1	518766.Rmar_0625	1.261e-62	222.0	COG1515@1|root,COG1515@2|Bacteria,4NI4J@976|Bacteroidetes,1FK2J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
YYD2_k127_5494558_0	573413.Spirs_1890	1.236e-114	395.0	COG0617@1|root,COG1418@1|root,COG0617@2|Bacteria,COG1418@2|Bacteria,2J5ZC@203691|Spirochaetes	203691|Spirochaetes	H	PolyA polymerase	papS	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
YYD2_k127_5494558_2	706587.Desti_4742	4.644e-20	96.0	2EH48@1|root,33AW7@2|Bacteria,1NIYU@1224|Proteobacteria,42XKK@68525|delta/epsilon subdivisions,2WSKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5494558_3	1267005.KB911256_gene1443	1.214e-12	72.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,3N798@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
YYD2_k127_550275_27	671143.DAMO_0267	6.939e-09	58.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
YYD2_k127_550275_15	631362.Thi970DRAFT_01597	4.893e-45	171.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1WWQB@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
YYD2_k127_550275_0	1343739.PAP_07605	3.152e-185	589.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
YYD2_k127_550275_5	1379270.AUXF01000006_gene245	3.929e-129	423.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
YYD2_k127_550275_22	1499967.BAYZ01000050_gene2820	1.203e-24	118.0	COG0074@1|root,COG0074@2|Bacteria,2NNZD@2323|unclassified Bacteria	2|Bacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
YYD2_k127_550275_9	309801.trd_1803	4.518e-84	282.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
YYD2_k127_550275_17	485915.Dret_2164	4.654e-41	155.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MBKB@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YYD2_k127_550275_24	1232410.KI421413_gene696	1.759e-20	98.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,43V81@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
YYD2_k127_550275_26	289376.THEYE_A1479	6.467e-14	72.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YYD2_k127_550275_7	585503.HMPREF7545_1138	5.513e-91	314.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4H1ZZ@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YYD2_k127_550275_6	580331.Thit_1283	1.835e-116	385.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YYD2_k127_550275_10	880073.Calab_0619	6.944e-84	288.0	COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria	2|Bacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
YYD2_k127_550275_12	1341151.ASZU01000004_gene113	3.734e-80	277.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,27BBK@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	KR domain	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
YYD2_k127_550275_21	648996.Theam_0392	5.611e-27	111.0	COG0236@1|root,COG0236@2|Bacteria,2G491@200783|Aquificae	200783|Aquificae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YYD2_k127_550275_1	997346.HMPREF9374_0894	5.693e-176	560.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YYD2_k127_550275_13	1379698.RBG1_1C00001G1823	2.732e-55	205.0	COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria	2|Bacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YYD2_k127_550275_23	1191523.MROS_2052	2.925e-23	114.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
YYD2_k127_550275_19	443144.GM21_1589	3.014e-37	159.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,43U1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
YYD2_k127_550275_18	880073.Calab_0781	1.02e-38	152.0	COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_550275_28	319225.Plut_0624	0.000394	51.0	COG5662@1|root,COG5662@2|Bacteria,1FE7W@1090|Chlorobi	1090|Chlorobi	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD2_k127_550275_25	509190.Cseg_1012	1.6e-15	90.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2KF74@204458|Caulobacterales	204458|Caulobacterales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_550275_8	1125863.JAFN01000001_gene2280	1.102e-84	295.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
YYD2_k127_550275_14	1121422.AUMW01000001_gene2545	1.227e-47	174.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,2621A@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
YYD2_k127_550275_20	1415780.JPOG01000001_gene2316	6.096e-34	136.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1X67R@135614|Xanthomonadales	135614|Xanthomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
YYD2_k127_550275_4	1379698.RBG1_1C00001G1502	3.066e-132	434.0	COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD2_k127_550275_2	1235279.C772_01205	7.194e-165	533.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,26D6P@186818|Planococcaceae	91061|Bacilli	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD2_k127_550275_16	1232410.KI421418_gene2259	6.628e-44	184.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,43RYS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YYD2_k127_550275_11	1379698.RBG1_1C00001G1858	6.461e-83	296.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
YYD2_k127_550275_3	1379698.RBG1_1C00001G0435	2.242e-140	499.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
YYD2_k127_553003_0	1267535.KB906767_gene880	5.076e-113	389.0	COG0612@1|root,COG0612@2|Bacteria,3Y2FB@57723|Acidobacteria,2JHWY@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
YYD2_k127_5543340_2	1286093.C266_04769	5.761e-50	201.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2VJES@28216|Betaproteobacteria,1JZP3@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
YYD2_k127_5543340_0	518766.Rmar_2194	2.047e-160	519.0	COG0160@1|root,COG0160@2|Bacteria,4NGPB@976|Bacteroidetes,1FITF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	-	Aminotran_3
YYD2_k127_5543340_3	1007105.PT7_2550	3.568e-19	92.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,3T49W@506|Alcaligenaceae	28216|Betaproteobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
YYD2_k127_5543340_1	404589.Anae109_4100	6.179e-130	421.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
YYD2_k127_5543869_2	243164.DET0542	6.524e-39	157.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi,34CM8@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_5543869_0	1123261.AXDW01000009_gene158	4.091e-84	282.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria,1X60R@135614|Xanthomonadales	135614|Xanthomonadales	P	Bacterioferritin (cytochrome b1)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD2_k127_5543869_1	1298863.AUEP01000004_gene2100	1.835e-49	197.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4DQH7@85009|Propionibacteriales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
YYD2_k127_5545186_3	1121423.JONT01000001_gene1996	5.567e-33	130.0	COG0073@1|root,COG0073@2|Bacteria,1V6N9@1239|Firmicutes,24JJZ@186801|Clostridia,2659H@186807|Peptococcaceae	186801|Clostridia	J	TIGRFAM export-related chaperone CsaA	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
YYD2_k127_5545186_2	1379698.RBG1_1C00001G0249	9.59e-40	150.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_5545186_1	269797.Mbar_A1616	1.571e-45	179.0	COG0613@1|root,arCOG00308@2157|Archaea,2Y8GF@28890|Euryarchaeota,2NBPP@224756|Methanomicrobia	224756|Methanomicrobia	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5545186_0	261292.Nit79A3_1298	6.625e-134	434.0	COG0425@1|root,COG0425@2|Bacteria,1R8DP@1224|Proteobacteria,2WFJB@28216|Betaproteobacteria,373Y3@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	AurF
YYD2_k127_5573357_1	290317.Cpha266_0860	1.409e-35	141.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD2_k127_5573357_0	330214.NIDE3360	1.059e-69	248.0	COG0823@1|root,COG0823@2|Bacteria,3J0U9@40117|Nitrospirae	40117|Nitrospirae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YYD2_k127_5578511_0	526227.Mesil_0256	1.032e-29	139.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
YYD2_k127_5578511_1	234267.Acid_0950	8.538e-28	132.0	COG0515@1|root,COG0515@2|Bacteria,3Y4M5@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_5584112_3	517418.Ctha_0896	5.771e-13	73.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	oprP	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
YYD2_k127_5584112_0	290397.Adeh_4006	2.047e-100	336.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YYD2_k127_5584112_1	290397.Adeh_4005	2.225e-96	327.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD2_k127_5584112_2	290397.Adeh_4004	7.962e-14	77.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
YYD2_k127_558783_6	247490.KSU1_A0013	5.588e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,2J3FA@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
YYD2_k127_558783_2	1161401.ASJA01000022_gene138	2.666e-76	269.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,43WX8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
YYD2_k127_558783_0	1379698.RBG1_1C00001G0312	1.155e-204	647.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YYD2_k127_558783_4	1122236.KB905146_gene1948	2.906e-25	106.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,2KP7H@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Ribosomal protein L31	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L31
YYD2_k127_558783_1	635013.TherJR_2905	6.018e-117	387.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,260RM@186807|Peptococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YYD2_k127_558783_3	518766.Rmar_1808	3.362e-53	199.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1FJ98@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25
YYD2_k127_558783_5	452637.Oter_2210	1.347e-15	90.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.5.1.23	ko:K12349	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00099	R01494	RC00064,RC00328	ko00000,ko00001,ko00002,ko01000	-	-	-	Ceramidase_alk,Ceramidse_alk_C
YYD2_k127_5590851_0	429009.Adeg_0304	1.369e-100	337.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
YYD2_k127_5605593_0	1121396.KB893052_gene3387	1.505e-37	150.0	COG1102@1|root,COG1102@2|Bacteria,1RCTZ@1224|Proteobacteria,42R0B@68525|delta/epsilon subdivisions,2WMVD@28221|Deltaproteobacteria,2MJH5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
YYD2_k127_5605593_1	1121378.KB899725_gene64	3.996e-28	123.0	COG2120@1|root,COG2120@2|Bacteria,1WIUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YYD2_k127_5605593_2	1528106.JRJE01000032_gene2538	6.062e-16	78.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,2JU6A@204441|Rhodospirillales	204441|Rhodospirillales	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
YYD2_k127_5609295_0	880073.Calab_2251	5.419e-27	123.0	COG4775@1|root,COG4775@2|Bacteria,2NQXR@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD2_k127_5611059_3	1379698.RBG1_1C00001G0957	2.206e-32	134.0	COG1293@1|root,COG1293@2|Bacteria,2NP83@2323|unclassified Bacteria	2|Bacteria	K	Fibronectin-binding protein A N-terminus (FbpA)	FbpA	-	3.1.21.3,3.2.1.170	ko:K01153,ko:K15524	-	-	-	-	ko00000,ko01000,ko02048	-	GH38	-	DUF814,FbpA
YYD2_k127_5611059_0	1125863.JAFN01000001_gene1723	4.332e-141	464.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YYD2_k127_5611059_2	1121430.JMLG01000005_gene717	4.421e-54	196.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae	186801|Clostridia	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
YYD2_k127_5611059_1	335541.Swol_2560	2.788e-86	304.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,42JS8@68298|Syntrophomonadaceae	186801|Clostridia	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
YYD2_k127_5637748_0	502025.Hoch_5723	4.601e-224	702.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YU4T@29|Myxococcales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YYD2_k127_5637748_2	1121104.AQXH01000001_gene1149	2.186e-14	85.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	-
YYD2_k127_5637748_1	404589.Anae109_2804	6.615e-69	247.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42SJR@68525|delta/epsilon subdivisions,2WRRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD2_k127_5638883_0	1144313.PMI10_03735	7.424e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1ICYX@117743|Flavobacteriia,2NW87@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
YYD2_k127_5643390_0	1408439.JHXW01000002_gene773	5.612e-22	100.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,379DH@32066|Fusobacteria	32066|Fusobacteria	G	PTS system, fructose-specific IIB	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
YYD2_k127_5643390_1	314230.DSM3645_13975	1.766e-21	106.0	COG1639@1|root,COG1639@2|Bacteria,2IZRQ@203682|Planctomycetes	203682|Planctomycetes	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
YYD2_k127_5644467_0	1232410.KI421428_gene1030	1.298e-79	273.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD2_k127_5645935_4	1274524.BSONL12_05933	0.0008835	45.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YYD2_k127_5645935_2	497964.CfE428DRAFT_2435	2.836e-36	155.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
YYD2_k127_5645935_3	1294142.CINTURNW_3665	1.177e-17	92.0	COG2068@1|root,COG2068@2|Bacteria,1UY6E@1239|Firmicutes,249PV@186801|Clostridia,36FU4@31979|Clostridiaceae	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	HD,NTP_transf_3
YYD2_k127_5645935_0	404589.Anae109_0100	1.054e-112	389.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
YYD2_k127_5645935_1	1499968.TCA2_1882	8.693e-83	288.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli,26RWE@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD2_k127_5657877_1	344747.PM8797T_16887	9.063e-09	66.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_5657877_0	880074.BARVI_05940	1.618e-62	228.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,2FPN9@200643|Bacteroidia,22XQM@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_5657877_2	381764.Fnod_0142	2.492e-06	57.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria,2GEAZ@200918|Thermotogae	200918|Thermotogae	O	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PDZ_2
YYD2_k127_5657900_1	1123060.JONP01000016_gene5478	2.628e-47	177.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,2JQGR@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD2_k127_5657900_3	344747.PM8797T_15181	6.735e-22	99.0	COG2331@1|root,COG2331@2|Bacteria,2J0TW@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YYD2_k127_5657900_0	644966.Tmar_2202	1.08e-107	361.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WCE5@538999|Clostridiales incertae sedis	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
YYD2_k127_5657900_2	926550.CLDAP_39650	5.873e-42	172.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YYD2_k127_5664254_3	1042326.AZNV01000008_gene2528	0.000151	53.0	COG0457@1|root,COG0457@2|Bacteria,1R5C2@1224|Proteobacteria,2UBAS@28211|Alphaproteobacteria,4BBCM@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_17,TPR_19
YYD2_k127_5664254_1	945713.IALB_0415	4.985e-75	286.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5664254_0	861299.J421_2976	6.127e-77	264.0	COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD2_k127_5664254_2	56780.SYN_01525	3.882e-57	211.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MQS8@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YYD2_k127_5664254_4	335543.Sfum_1239	0.0008195	42.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MR54@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YYD2_k127_567272_5	580331.Thit_1977	3.835e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,42EPJ@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD2_k127_567272_7	1121447.JONL01000001_gene735	9.57e-05	46.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_567272_1	269799.Gmet_0057	8.531e-134	472.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
YYD2_k127_567272_2	880073.Calab_1889	2.786e-53	213.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,SSF,SpoIIE
YYD2_k127_567272_3	795666.MW7_1842	4.227e-44	169.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1K0T3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
YYD2_k127_567272_4	338963.Pcar_0103	1.438e-38	166.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,42RJ4@68525|delta/epsilon subdivisions,2WNQ3@28221|Deltaproteobacteria,43SZQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
YYD2_k127_567272_0	1227349.C170_05408	9.608e-137	449.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,26QQ5@186822|Paenibacillaceae	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
YYD2_k127_568613_0	518766.Rmar_2045	2.789e-86	289.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1FIPT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YYD2_k127_568613_2	1379698.RBG1_1C00001G0229	4.504e-10	70.0	2BIY5@1|root,32D6E@2|Bacteria,2NRW7@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_568613_1	123899.JPQP01000017_gene2186	2.189e-33	133.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,3T3XD@506|Alcaligenaceae	28216|Betaproteobacteria	J	endoribonuclease	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YYD2_k127_5688696_2	1254432.SCE1572_08670	4.265e-37	147.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
YYD2_k127_5688696_0	234267.Acid_1998	9.166e-133	431.0	COG0667@1|root,COG0667@2|Bacteria,3Y35T@57723|Acidobacteria	57723|Acidobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_5688696_1	396588.Tgr7_0007	6.518e-84	289.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YYD2_k127_5688696_3	278957.ABEA03000174_gene3406	9.44e-09	67.0	29WZ7@1|root,30IME@2|Bacteria,46Y1Z@74201|Verrucomicrobia,3K8U0@414999|Opitutae	414999|Opitutae	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_569113_2	743299.Acife_1149	4.566e-75	262.0	29CPA@1|root,2ZZMJ@2|Bacteria,1QWMK@1224|Proteobacteria,1T56K@1236|Gammaproteobacteria,2NE6S@225057|Acidithiobacillales	1224|Proteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
YYD2_k127_569113_4	309801.trd_A0914	4.351e-13	76.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_03510	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	EamA
YYD2_k127_569113_0	323261.Noc_2839	8.878e-97	326.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X250@135613|Chromatiales	135613|Chromatiales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD2_k127_569113_1	880073.Calab_2811	2.808e-87	320.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2NPC4@2323|unclassified Bacteria	2|Bacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,TrkA_C,Voltage_CLC
YYD2_k127_569113_3	335543.Sfum_1157	1.488e-32	128.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria,2MRHM@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
YYD2_k127_5695372_4	768710.DesyoDRAFT_0167	8.694e-20	95.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YYD2_k127_5695372_2	644282.Deba_1280	2.94e-90	325.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YYD2_k127_5695372_0	243231.GSU3089	2.729e-126	443.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43U19@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YYD2_k127_5695372_3	1379698.RBG1_1C00001G1480	1.107e-21	106.0	COG1579@1|root,COG1579@2|Bacteria,2NPW0@2323|unclassified Bacteria	2|Bacteria	S	C4-type zinc ribbon domain	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
YYD2_k127_5695372_5	34506.g3068	1.67e-09	69.0	2D1ZE@1|root,2SJVP@2759|Eukaryota,3AI9D@33154|Opisthokonta,3BX0X@33208|Metazoa,3DEMU@33213|Bilateria	33208|Metazoa	S	LppC putative lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LppC
YYD2_k127_5695372_7	1000565.METUNv1_02021	0.0002172	55.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2VN72@28216|Betaproteobacteria,2KU7A@206389|Rhodocyclales	206389|Rhodocyclales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	PMT_2
YYD2_k127_5695372_1	880073.Calab_2849	1.808e-112	384.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
YYD2_k127_571059_2	309807.SRU_1974	2.806e-43	170.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1FJB8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD2_k127_571059_0	1123368.AUIS01000031_gene1422	3.654e-129	421.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_571059_1	926554.KI912628_gene2730	1.623e-100	339.0	COG0667@1|root,COG0667@2|Bacteria,1WJPF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_571059_4	1304875.JAFZ01000004_gene476	0.0008282	42.0	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5718440_3	1122176.KB903547_gene1064	3.134e-05	48.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YYD2_k127_5718440_2	1284352.AOIG01000031_gene208	4.215e-31	129.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,26R52@186822|Paenibacillaceae	91061|Bacilli	S	protein with conserved CXXC pairs	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
YYD2_k127_5718440_1	1379270.AUXF01000006_gene305	2.476e-88	312.0	COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
YYD2_k127_5718440_0	760568.Desku_3183	5.835e-181	578.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YYD2_k127_5724236_0	555079.Toce_0008	4.291e-204	646.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,42FIB@68295|Thermoanaerobacterales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YYD2_k127_5724236_1	1379698.RBG1_1C00001G0271	2.54e-135	436.0	COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YYD2_k127_5729391_0	373903.Hore_18840	4.229e-84	287.0	COG1215@1|root,COG1215@2|Bacteria,1VS3N@1239|Firmicutes,24XJR@186801|Clostridia,3WBK3@53433|Halanaerobiales	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5729391_1	1499967.BAYZ01000080_gene958	2.025e-65	253.0	COG1044@1|root,COG1044@2|Bacteria,2NQT1@2323|unclassified Bacteria	2|Bacteria	M	SpoIVB peptidase S55	-	-	2.7.7.24	ko:K00973,ko:K02414,ko:K21449	ko00521,ko00523,ko00525,ko01130,ko02040,map00521,map00523,map00525,map01130,map02040	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko02035	1.B.40.2	-	-	AMP-binding,APH,DUF4114,DUF4842,Hexapep,PP-binding,Peptidase_S55
YYD2_k127_5729391_2	234267.Acid_0265	2.025e-44	176.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
YYD2_k127_5740048_0	1340493.JNIF01000003_gene2186	1.756e-260	848.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YYD2_k127_5743477_1	903818.KI912268_gene2233	1.598e-38	145.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YYD2_k127_5743477_2	639030.JHVA01000001_gene3618	7.969e-23	106.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria,2JJM8@204432|Acidobacteriia	204432|Acidobacteriia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YYD2_k127_5743477_3	983548.Krodi_1221	1.388e-10	70.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia,37F6X@326319|Dokdonia	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD2_k127_5743477_0	742738.HMPREF9460_00063	1.976e-68	243.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,2688N@186813|unclassified Clostridiales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD2_k127_5768692_0	1379698.RBG1_1C00001G1725	0.0	1282.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
YYD2_k127_5769436_3	113355.CM001775_gene1664	0.0007487	49.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
YYD2_k127_5769436_0	1121033.AUCF01000013_gene1686	1.222e-46	181.0	COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,2TXDS@28211|Alphaproteobacteria,2JTYI@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD2_k127_5769436_2	314256.OG2516_14341	8.732e-14	82.0	COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,2TXDS@28211|Alphaproteobacteria,2PEWF@252301|Oceanicola	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD2_k127_5769436_1	644966.Tmar_0783	3.563e-29	133.0	COG0419@1|root,COG0419@2|Bacteria,1UMHS@1239|Firmicutes,25GIK@186801|Clostridia,3WDIT@538999|Clostridiales incertae sedis	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
YYD2_k127_577454_1	445970.ALIPUT_00361	6.607e-72	249.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia,22U1B@171550|Rikenellaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
YYD2_k127_577454_4	1267533.KB906734_gene3938	1.263e-10	66.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YYD2_k127_577454_2	575788.VS_1608	1.924e-32	136.0	COG1247@1|root,COG1247@2|Bacteria,1RC8Z@1224|Proteobacteria,1THNM@1236|Gammaproteobacteria,1XWXT@135623|Vibrionales	135623|Vibrionales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
YYD2_k127_577454_0	426117.M446_6009	4.616e-73	252.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2TRRV@28211|Alphaproteobacteria,1JUWV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Phosphoenolpyruvate phosphomutase	MA20_35565	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
YYD2_k127_5781267_2	1123367.C666_05705	0.0009726	42.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2VSF6@28216|Betaproteobacteria,2KWMP@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
YYD2_k127_5781267_0	518766.Rmar_1795	1.135e-137	444.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1FJC0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YYD2_k127_5781872_1	1379698.RBG1_1C00001G0278	7.585e-117	387.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YYD2_k127_5781872_2	379066.GAU_1881	1.049e-51	190.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
YYD2_k127_5781872_0	525904.Tter_0977	0.0	1045.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YYD2_k127_5781872_3	1131730.BAVI_03369	2.54e-30	130.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HHTW@91061|Bacilli,1ZQYF@1386|Bacillus	91061|Bacilli	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
YYD2_k127_5789594_3	1341151.ASZU01000003_gene2690	1.639e-32	133.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27BBV@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YYD2_k127_5789594_1	1121422.AUMW01000036_gene2700	1.032e-40	159.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24NFX@186801|Clostridia,2624K@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
YYD2_k127_5789594_0	483219.LILAB_14080	1.312e-68	253.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,43C12@68525|delta/epsilon subdivisions,2WXMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD2_k127_5789594_2	648996.Theam_1071	9.03e-35	150.0	COG0542@1|root,COG0542@2|Bacteria,2G3N7@200783|Aquificae	200783|Aquificae	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YYD2_k127_5789594_4	370438.PTH_1386	5.698e-19	88.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YYD2_k127_5789965_2	324925.Ppha_0987	5.129e-32	132.0	COG2318@1|root,COG2318@2|Bacteria,1FF75@1090|Chlorobi	1090|Chlorobi	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD2_k127_5789965_1	690850.Desaf_0801	4.067e-32	134.0	2A1V8@1|root,30Q4E@2|Bacteria,1Q12F@1224|Proteobacteria,43EUK@68525|delta/epsilon subdivisions,2X1T9@28221|Deltaproteobacteria,2MFMU@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5789965_0	644966.Tmar_1355	3.932e-41	169.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WD8J@538999|Clostridiales incertae sedis	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07642,ko:K07652,ko:K10681	ko02020,map02020	M00450,M00459,M00468,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegV,HAMP,HATPase_c,HisKA,Hpt,Response_reg
YYD2_k127_5802860_0	1192034.CAP_2016	7.132e-30	139.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YU18@29|Myxococcales	28221|Deltaproteobacteria	KLT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,Pkinase
YYD2_k127_5804921_0	404589.Anae109_4301	1.208e-176	568.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,430DD@68525|delta/epsilon subdivisions,2WVKB@28221|Deltaproteobacteria,2YUBR@29|Myxococcales	28221|Deltaproteobacteria	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	ligB	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YYD2_k127_58129_3	1123367.C666_11410	1.218e-14	83.0	COG2010@1|root,COG2010@2|Bacteria,1N7I9@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_58129_2	448385.sce0681	5.433e-46	183.0	COG1595@1|root,COG1595@2|Bacteria,1N3BR@1224|Proteobacteria	1224|Proteobacteria	K	rna polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD2_k127_58129_0	1379270.AUXF01000001_gene1941	3.915e-81	305.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
YYD2_k127_58129_1	1123024.AUII01000052_gene3914	4.61e-60	215.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD2_k127_5819438_4	641491.DND132_1650	1e-99	341.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2M838@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YYD2_k127_5819438_2	1144275.COCOR_06090	1.08e-113	379.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YYD2_k127_5819438_7	330214.NIDE0765	3.084e-06	59.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589,ko:K06438	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
YYD2_k127_5819438_0	1316927.ATKI01000143_gene4090	1.297e-146	481.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1YQ0R@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD2_k127_5819438_5	401526.TcarDRAFT_0182	1.062e-79	296.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4H294@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YYD2_k127_5819438_6	330214.NIDE0760	1.82e-61	228.0	COG0772@1|root,COG0772@2|Bacteria,3J0M8@40117|Nitrospirae	40117|Nitrospirae	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YYD2_k127_5819438_3	429009.Adeg_1566	5.522e-105	356.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
YYD2_k127_5819438_1	1379698.RBG1_1C00001G0393	1.586e-140	457.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
YYD2_k127_5819438_8	1223543.GP2_028_00210	2.848e-05	47.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4GA43@85026|Gordoniaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD2_k127_5823545_0	580327.Tthe_2116	6.355e-202	639.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
YYD2_k127_5836084_2	76636.JOEC01000001_gene375	9.864e-06	60.0	COG1361@1|root,COG2373@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,2I8F1@201174|Actinobacteria,4FMYQ@85023|Microbacteriaceae	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YYD2_k127_5836084_1	404589.Anae109_1268	2.839e-48	183.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2Z304@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YYD2_k127_5836084_0	518766.Rmar_0288	3.048e-55	211.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4NI98@976|Bacteroidetes	976|Bacteroidetes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
YYD2_k127_583976_1	1316936.K678_14187	1.47e-27	127.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2JPSX@204441|Rhodospirillales	204441|Rhodospirillales	M	NmrA-like family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
YYD2_k127_583976_0	886293.Sinac_5836	1.389e-30	125.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD2_k127_583976_2	1499967.BAYZ01000177_gene5755	4.933e-06	49.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
YYD2_k127_5840182_3	222534.KB893672_gene2980	1.399e-29	131.0	COG1397@1|root,COG1397@2|Bacteria,2GKHI@201174|Actinobacteria,4ET0I@85013|Frankiales	201174|Actinobacteria	OT	ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH,DSPc
YYD2_k127_5840182_1	429009.Adeg_0372	8.784e-109	364.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,42FFM@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YYD2_k127_5840182_0	324602.Caur_1772	0.0	1223.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,375DP@32061|Chloroflexia	32061|Chloroflexia	F	Carbamoyl-phosphate synthetase large chain domain protein	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YYD2_k127_5840182_2	234267.Acid_6345	2.344e-35	143.0	COG1533@1|root,COG1533@2|Bacteria,3Y2S5@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD2_k127_584889_2	404589.Anae109_2759	0.0004132	44.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,42WEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	cytochrome c	norC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
YYD2_k127_584889_0	404589.Anae109_2758	3.246e-220	690.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
YYD2_k127_584889_1	1245475.ANAE01000088_gene1386	2.728e-28	126.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD2_k127_5888095_0	502025.Hoch_3647	2.06e-179	571.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YYD2_k127_5888095_1	596151.DesfrDRAFT_4136	8.845e-51	191.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,2M9W5@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Homocysteine S-methyltransferase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
YYD2_k127_5888095_2	861299.J421_1385	0.0007327	51.0	COG2062@1|root,COG2062@2|Bacteria,1ZU0U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
YYD2_k127_590452_2	862908.BMS_2495	5.759e-34	134.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD2_k127_590452_3	66875.JODY01000030_gene3996	8.707e-11	76.0	COG3595@1|root,COG3595@2|Bacteria,2I8IR@201174|Actinobacteria	201174|Actinobacteria	T	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YYD2_k127_590452_0	459349.CLOAM1019	6.042e-122	417.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	3.6.3.44	ko:K06147,ko:K06148,ko:K11085,ko:K16787,ko:K18104,ko:K18889	ko01501,ko02010,map01501,map02010	M00582,M00700,M00707	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
YYD2_k127_590452_1	326427.Cagg_2627	3.906e-119	405.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,37630@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD2_k127_5911206_2	880073.Calab_0853	4.234e-25	111.0	COG2262@1|root,COG2262@2|Bacteria,2NNWI@2323|unclassified Bacteria	2|Bacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YYD2_k127_5911206_0	1121004.ATVC01000112_gene2188	5.208e-119	396.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,2VI3J@28216|Betaproteobacteria,2KPJA@206351|Neisseriales	206351|Neisseriales	S	xanthine uracil permease family protein K06901	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
YYD2_k127_5911206_1	266117.Rxyl_1482	4.113e-34	146.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD2_k127_5911206_3	309807.SRU_1974	1.71e-05	48.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1FJB8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD2_k127_5917037_0	1379698.RBG1_1C00001G0436	1.8e-48	183.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD2_k127_5923181_0	56780.SYN_01499	4.098e-54	198.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MQBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
YYD2_k127_5923181_1	330214.NIDE1616	4.617e-10	72.0	2DM57@1|root,31S0Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_5923181_2	1382304.JNIL01000001_gene3057	3.555e-09	64.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,4HADV@91061|Bacilli	91061|Bacilli	J	Alanyl-tRNA synthetase	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD2_k127_5923869_3	1429851.X548_11885	4.439e-92	317.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1S4G6@1236|Gammaproteobacteria,1X3NS@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
YYD2_k127_5923869_2	1123073.KB899241_gene2803	6.801e-108	359.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1S6CY@1236|Gammaproteobacteria,1X3CM@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC-type sugar transport systems, permease components	lacF	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
YYD2_k127_5923869_1	215803.DB30_8575	3.202e-139	461.0	COG1653@1|root,COG1653@2|Bacteria,1MX59@1224|Proteobacteria	1224|Proteobacteria	G	ABC transporter substrate-binding protein	malE	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
YYD2_k127_5923869_0	215803.DB30_8576	3.066e-183	586.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria	1224|Proteobacteria	N	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
YYD2_k127_5931406_1	1379698.RBG1_1C00001G1789	2.341e-83	307.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
YYD2_k127_5931406_0	300852.55772292	5.795e-103	362.0	COG0557@1|root,COG0557@2|Bacteria,1WI1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_IclR,OB_RNB,RNB,S1
YYD2_k127_5932964_1	1382356.JQMP01000003_gene2001	7.522e-95	329.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi,27Y0D@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
YYD2_k127_5932964_2	1379270.AUXF01000005_gene399	2.585e-90	317.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YYD2_k127_5932964_4	665571.STHERM_c06620	6.967e-17	91.0	COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
YYD2_k127_5932964_0	572479.Hprae_0246	6.491e-114	384.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WA5V@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YYD2_k127_5932964_5	1234664.AMRO01000001_gene2338	1.573e-06	57.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,1WFR5@129337|Geobacillus	91061|Bacilli	S	YacP-like NYN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
YYD2_k127_5932964_3	1487953.JMKF01000053_gene1899	3.501e-46	171.0	COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria,1H9IP@1150|Oscillatoriales	1117|Cyanobacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD2_k127_5935429_18	321327.CYA_1894	6.682e-10	67.0	COG4398@1|root,COG4398@2|Bacteria,1G0TB@1117|Cyanobacteria,1GYRY@1129|Synechococcus	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
YYD2_k127_5935429_5	1509405.GV67_19485	2.42e-113	385.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2VF2U@28211|Alphaproteobacteria,4BMCM@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD2_k127_5935429_4	1230476.C207_02133	4.4e-115	385.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,3JU8X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD2_k127_5935429_8	1379698.RBG1_1C00001G0988	1.96e-68	267.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
YYD2_k127_5935429_3	404589.Anae109_1279	5.944e-122	408.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YYD2_k127_5935429_2	639282.DEFDS_1973	5.084e-140	465.0	COG1008@1|root,COG1008@2|Bacteria,2GF24@200930|Deferribacteres	200930|Deferribacteres	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YYD2_k127_5935429_0	880073.Calab_2685	2.394e-204	661.0	COG1009@1|root,COG1009@2|Bacteria,2NNM8@2323|unclassified Bacteria	2|Bacteria	CP	NADH-quinone oxidoreductase chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
YYD2_k127_5935429_16	404589.Anae109_1282	1.103e-26	119.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42WIQ@68525|delta/epsilon subdivisions,2WS3A@28221|Deltaproteobacteria,2Z1V8@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YYD2_k127_5935429_15	319225.Plut_0749	1.371e-33	139.0	COG0839@1|root,COG0839@2|Bacteria,1FDZK@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YYD2_k127_5935429_12	1191523.MROS_2374	1.129e-37	148.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K03615,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
YYD2_k127_5935429_6	880073.Calab_2689	4.41e-107	359.0	COG1005@1|root,COG1005@2|Bacteria,2NQIK@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YYD2_k127_5935429_1	1191523.MROS_2376	1.328e-152	495.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YYD2_k127_5935429_11	269798.CHU_0511	2.778e-40	163.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,47PNZ@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YYD2_k127_5935429_9	1123242.JH636436_gene424	5.161e-67	241.0	COG0377@1|root,COG0377@2|Bacteria,2IY3F@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD2_k127_5935429_13	1191523.MROS_2379	1.942e-35	140.0	COG0838@1|root,COG0838@2|Bacteria	2|Bacteria	C	NADH dehydrogenase (ubiquinone) activity	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330,ko:K05574	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YYD2_k127_5935429_10	161156.JQKW01000010_gene375	5.569e-41	158.0	COG0566@1|root,COG0566@2|Bacteria,2GHKT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
YYD2_k127_5935429_14	298655.KI912266_gene1280	2.029e-34	143.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4ERJW@85013|Frankiales	201174|Actinobacteria	T	protein phosphatase 2C domain protein	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
YYD2_k127_5935429_7	1380394.JADL01000001_gene3101	1.646e-95	331.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2JV5D@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
YYD2_k127_5935429_17	530564.Psta_4154	2.504e-17	96.0	COG1305@1|root,COG1305@2|Bacteria,2IYTT@203682|Planctomycetes	203682|Planctomycetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
YYD2_k127_5938989_0	1232410.KI421415_gene3041	1.901e-46	186.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43S3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	TilS substrate binding domain	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YYD2_k127_5945704_1	1121033.AUCF01000016_gene5441	4.032e-13	83.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria,2JT2W@204441|Rhodospirillales	204441|Rhodospirillales	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_4,TPR_7
YYD2_k127_5945704_0	1128421.JAGA01000002_gene62	7.666e-71	248.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD2_k127_5956557_0	1192034.CAP_6838	1.058e-120	418.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42Z9H@68525|delta/epsilon subdivisions,2WUIK@28221|Deltaproteobacteria,2YUAX@29|Myxococcales	28221|Deltaproteobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
YYD2_k127_5956557_1	264732.Moth_0874	5.342e-98	330.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,42FQ5@68295|Thermoanaerobacterales	186801|Clostridia	V	pfam abc	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
YYD2_k127_5956557_2	1232410.KI421416_gene2620	7.32e-72	274.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,42N8F@68525|delta/epsilon subdivisions,2WK3B@28221|Deltaproteobacteria,43U4Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
YYD2_k127_5956557_6	7091.BGIBMGA001024-TA	0.000155	55.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,41W55@6656|Arthropoda,3SG5T@50557|Insecta,442B1@7088|Lepidoptera	33208|Metazoa	S	Domain of unknown function (DUF1736)	TMTC3	GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
YYD2_k127_5956557_3	643648.Slip_1112	3.891e-59	226.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,42JKX@68298|Syntrophomonadaceae	186801|Clostridia	J	Protein of unknown function (DUF933)	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YYD2_k127_5956557_4	880073.Calab_3451	4.899e-15	87.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
YYD2_k127_5967779_4	1236959.BAMT01000010_gene3316	1.332e-06	60.0	2DKYH@1|root,30WKQ@2|Bacteria,1RCXC@1224|Proteobacteria,2VR6P@28216|Betaproteobacteria,2KN4S@206350|Nitrosomonadales	206350|Nitrosomonadales	S	TIGRFAM EpsI family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
YYD2_k127_5967779_0	1232410.KI421418_gene2414	2.822e-38	159.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,43U07@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
YYD2_k127_5967779_1	1232410.KI421418_gene2330	6.144e-29	135.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WN1C@28221|Deltaproteobacteria,43S7E@69541|Desulfuromonadales	28221|Deltaproteobacteria	DM	Chain length determinant protein	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
YYD2_k127_5967779_2	471874.PROSTU_00493	1.419e-22	113.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,3Z7R8@586|Providencia	1236|Gammaproteobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YYD2_k127_5967779_3	1126627.BAWE01000005_gene6442	4.623e-12	77.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,3JSHU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
YYD2_k127_5997997_2	316056.RPC_0641	8.811e-57	202.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,3JU06@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD2_k127_5997997_1	1267533.KB906734_gene3652	4.41e-80	276.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
YYD2_k127_5997997_0	1379698.RBG1_1C00001G0516	6.699e-129	434.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD2_k127_5997997_3	1125863.JAFN01000001_gene3467	1.148e-30	129.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YYD2_k127_6005700_2	1042877.GQS_00080	0.000276	53.0	arCOG03264@1|root,arCOG03264@2157|Archaea,2Y50J@28890|Euryarchaeota,244SG@183968|Thermococci	183968|Thermococci	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
YYD2_k127_6005700_1	1123501.KB902299_gene3682	1.665e-10	74.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1520 FOG WD40-like repeat	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
YYD2_k127_6005700_0	1379698.RBG1_1C00001G1445	2.954e-90	314.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
YYD2_k127_6007899_4	1123401.JHYQ01000006_gene116	1.107e-32	127.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales	72273|Thiotrichales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YYD2_k127_6007899_3	1379698.RBG1_1C00001G0425	1.291e-61	218.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD2_k127_6007899_2	264732.Moth_0582	4.151e-78	286.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
YYD2_k127_6007899_0	644282.Deba_0611	7.417e-106	355.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,42P3H@68525|delta/epsilon subdivisions,2WK0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_6007899_1	1499967.BAYZ01000017_gene6221	6.555e-84	297.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
YYD2_k127_6008518_1	926562.Oweho_2865	2.697e-06	61.0	COG4206@1|root,COG4772@1|root,COG4206@2|Bacteria,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YYD2_k127_6008518_0	937777.Deipe_2665	6.201e-13	74.0	COG4448@1|root,COG4448@2|Bacteria,1WIDX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
YYD2_k127_6010817_2	575540.Isop_2730	2.444e-156	505.0	COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
YYD2_k127_6010817_4	502025.Hoch_4654	3.108e-127	416.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,42PDK@68525|delta/epsilon subdivisions,2WJKJ@28221|Deltaproteobacteria,2YTX7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
YYD2_k127_6010817_0	290397.Adeh_1230	1.225e-296	917.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria,2YUIB@29|Myxococcales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
YYD2_k127_6010817_6	391625.PPSIR1_25216	1.771e-31	143.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria,2YUIB@29|Myxococcales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
YYD2_k127_6010817_3	1232410.KI421418_gene2202	3.058e-155	499.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,42N0R@68525|delta/epsilon subdivisions,2WMPF@28221|Deltaproteobacteria,43U7D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Fer2_BFD
YYD2_k127_6010817_1	1211115.ALIQ01000235_gene2602	2.793e-166	531.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,3NCBS@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24
YYD2_k127_6010817_7	292564.Cyagr_1939	1.839e-29	122.0	COG0286@1|root,COG0286@2|Bacteria,1G2AI@1117|Cyanobacteria,22SHX@167375|Cyanobium	1117|Cyanobacteria	V	Type I restriction-modification system methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
YYD2_k127_6010817_5	1123392.AQWL01000005_gene3018	6.166e-44	163.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VKXG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	3-Demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
YYD2_k127_601307_0	316067.Geob_3079	5.863e-72	270.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_601998_1	1121920.AUAU01000006_gene301	2.734e-51	190.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_601998_0	215803.DB30_8621	4.481e-69	265.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
YYD2_k127_6026187_2	684949.ATTJ01000003_gene3134	5.491e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,1WKZV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_6026187_0	1382306.JNIM01000001_gene2604	1.94e-147	486.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
YYD2_k127_6026187_1	326427.Cagg_2109	8.187e-85	310.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YYD2_k127_6029867_5	1379698.RBG1_1C00001G1645	9.861e-49	182.0	COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
YYD2_k127_6029867_1	671143.DAMO_1646	2.483e-93	332.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YYD2_k127_6029867_3	1049564.TevJSym_ao00230	2.702e-61	226.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1SYTB@1236|Gammaproteobacteria,1J7DI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YYD2_k127_6029867_2	1379698.RBG1_1C00001G1648	6.715e-75	259.0	COG1043@1|root,COG1043@2|Bacteria,2NP5V@2323|unclassified Bacteria	2|Bacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YYD2_k127_6029867_0	1379698.RBG1_1C00001G1649	2.727e-134	449.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
YYD2_k127_6029867_4	1379698.RBG1_1C00001G1848	2.423e-53	192.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
YYD2_k127_6031504_1	497964.CfE428DRAFT_6304	6.483e-133	439.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
YYD2_k127_6031504_0	1500893.JQNB01000001_gene930	1.217e-134	448.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1X2ZR@135614|Xanthomonadales	135614|Xanthomonadales	G	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
YYD2_k127_6031504_2	530564.Psta_2541	8.768e-69	241.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
YYD2_k127_6033494_0	1158150.KB906246_gene1915	0.0	1371.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
YYD2_k127_6033494_1	1158150.KB906246_gene1914	2.388e-157	503.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
YYD2_k127_6033631_3	1000565.METUNv1_03348	1.494e-20	106.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD2_k127_6033631_1	316274.Haur_1809	9.987e-48	182.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	2|Bacteria	P	PFAM ABC transporter related	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YYD2_k127_6033631_4	335283.Neut_2150	1.92e-10	67.0	2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,2WBFI@28216|Betaproteobacteria,373DI@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6033631_0	56780.SYN_00535	7.791e-57	213.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2MS0Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YYD2_k127_6033631_2	56780.SYN_00536	2.343e-22	106.0	COG1708@1|root,COG1708@2|Bacteria,1NMP8@1224|Proteobacteria,42Y4J@68525|delta/epsilon subdivisions,2WSMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6042_2	880073.Calab_1875	9.381e-40	155.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD2_k127_6042_0	1379698.RBG1_1C00001G0201	2.425e-132	432.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD2_k127_6042_1	1379698.RBG1_1C00001G0202	1.509e-93	316.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YYD2_k127_6042_3	929556.Solca_0931	1.301e-11	73.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
YYD2_k127_6054044_1	760568.Desku_0294	1.823e-106	354.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,260D6@186807|Peptococcaceae	186801|Clostridia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
YYD2_k127_6054044_3	390874.Tpet_1749	2.79e-15	89.0	COG0526@1|root,COG0526@2|Bacteria,2GD8V@200918|Thermotogae	200918|Thermotogae	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YYD2_k127_6054044_0	575540.Isop_2571	1.531e-156	507.0	COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes	203682|Planctomycetes	P	COG0798 Arsenite efflux pump ACR3 and related	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YYD2_k127_6054044_2	530564.Psta_4632	8.742e-37	141.0	COG0394@1|root,COG0394@2|Bacteria,2J0IQ@203682|Planctomycetes	203682|Planctomycetes	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
YYD2_k127_6070462_2	1541065.JRFE01000006_gene4739	3.64e-11	72.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,3VKZ2@52604|Pleurocapsales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_6070462_0	926550.CLDAP_25710	1.175e-34	139.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
YYD2_k127_6070462_1	1499967.BAYZ01000148_gene1744	9.36e-12	73.0	2CG94@1|root,337GB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6070462_3	1089547.KB913013_gene4394	1.636e-05	57.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
YYD2_k127_6070691_0	309807.SRU_1916	1.765e-18	88.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4PM65@976|Bacteroidetes,1FKEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
YYD2_k127_6070691_1	448385.sce7933	2.14e-18	87.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria,2Z0Y9@29|Myxococcales	28221|Deltaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YYD2_k127_6076967_0	1499967.BAYZ01000011_gene5215	4.953e-176	591.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
YYD2_k127_6085986_0	1267535.KB906767_gene784	6.059e-31	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD2_k127_6091997_3	338969.Rfer_0689	1.33e-18	91.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,4ABQ6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
YYD2_k127_6091997_0	926550.CLDAP_39770	6.726e-125	411.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD2_k127_6091997_1	316274.Haur_3900	5.787e-84	289.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD2_k127_6091997_4	1045855.DSC_05445	3.331e-07	63.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1X503@135614|Xanthomonadales	135614|Xanthomonadales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
YYD2_k127_6091997_2	401053.AciPR4_3332	1.285e-20	98.0	COG3536@1|root,COG3536@2|Bacteria,3Y4UI@57723|Acidobacteria,2JJF2@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
YYD2_k127_610067_1	1278073.MYSTI_03884	2.786e-86	295.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla6	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_610067_0	518766.Rmar_0302	2.909e-155	505.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1FISX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
YYD2_k127_610067_3	404589.Anae109_1306	2.583e-63	230.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2YW8E@29|Myxococcales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
YYD2_k127_610067_4	652103.Rpdx1_2709	5.951e-54	199.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,3K2VA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
YYD2_k127_610067_7	1089550.ATTH01000001_gene2518	1.503e-29	124.0	COG0526@1|root,COG0526@2|Bacteria,4PIEG@976|Bacteroidetes,1FK6M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD2_k127_610067_6	867903.ThesuDRAFT_02292	1.072e-40	164.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WDGV@538999|Clostridiales incertae sedis	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
YYD2_k127_610067_2	517418.Ctha_0236	4.242e-75	282.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_610067_5	1122194.AUHU01000006_gene514	6.966e-45	172.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
YYD2_k127_615633_0	309807.SRU_1258	8.026e-120	406.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
YYD2_k127_615633_1	871963.Desdi_2890	1.181e-34	154.0	COG0438@1|root,COG0438@2|Bacteria,1VTEP@1239|Firmicutes,24DKY@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD2_k127_6171907_0	575540.Isop_3553	9.338e-42	175.0	COG0457@1|root,COG0457@2|Bacteria,2IZ0D@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6177026_0	401526.TcarDRAFT_1997	1.829e-312	984.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4H20U@909932|Negativicutes	1239|Firmicutes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YYD2_k127_6177026_7	1303518.CCALI_01175	1.18e-17	84.0	COG0607@1|root,32YCZ@2|Bacteria	2|Bacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YYD2_k127_6177026_2	448385.sce5264	4.577e-152	486.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42YJ9@68525|delta/epsilon subdivisions,2WTRB@28221|Deltaproteobacteria,2YZPH@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD2_k127_6177026_8	670487.Ocepr_0458	3.817e-16	92.0	COG1664@1|root,COG1664@2|Bacteria,1WKED@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD2_k127_6177026_3	485915.Dret_0280	1.172e-149	484.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD2_k127_6177026_6	1096546.WYO_3961	5.505e-23	115.0	COG0535@1|root,COG0535@2|Bacteria,1NJZV@1224|Proteobacteria,2U4H8@28211|Alphaproteobacteria,1JSDQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
YYD2_k127_6177026_5	945550.VISI1226_05954	3.729e-31	138.0	COG2227@1|root,COG2227@2|Bacteria,1QXQ4@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD2_k127_6177026_1	1403819.BATR01000162_gene5395	2.107e-166	539.0	COG0457@1|root,COG0457@2|Bacteria,46W9Q@74201|Verrucomicrobia,2IVDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6177026_4	1254432.SCE1572_02795	2.377e-61	218.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_6187227_2	1382304.JNIL01000001_gene1028	1.906e-31	134.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0403 family	yphP	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
YYD2_k127_6187227_1	76114.ebA6557	3.922e-57	202.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6187227_0	243274.THEMA_02295	3.076e-101	344.0	COG0162@1|root,COG0162@2|Bacteria,2GCKH@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iLJ478.TM0478	S4,tRNA-synt_1b
YYD2_k127_6187227_4	1499967.BAYZ01000002_gene5902	0.0001692	53.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2NS18@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
YYD2_k127_6187743_0	443143.GM18_1480	8.093e-71	252.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
YYD2_k127_6187743_1	871968.DESME_12280	2.527e-62	231.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD2_k127_6199818_2	1121918.ARWE01000001_gene1405	2.952e-11	74.0	COG0640@1|root,COG0640@2|Bacteria,1PCBT@1224|Proteobacteria,42W4D@68525|delta/epsilon subdivisions,2WSFX@28221|Deltaproteobacteria,43V48@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
YYD2_k127_6199818_4	1122951.ATUE01000005_gene1919	1.312e-07	63.0	2EUPJ@1|root,33N5B@2|Bacteria,1NV2N@1224|Proteobacteria,1SNKW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6199818_0	1379698.RBG1_1C00001G0825	1.285e-36	154.0	28P4Q@1|root,2ZBZV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6199818_1	1499967.BAYZ01000164_gene6670	2.335e-36	153.0	COG3907@1|root,COG3907@2|Bacteria	2|Bacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD2_k127_6201589_0	1246995.AFR_17080	2.231e-162	522.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD2_k127_6201589_1	861299.J421_4428	4.019e-58	207.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YYD2_k127_6209346_1	880073.Calab_0876	4.169e-154	500.0	COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD2_k127_6209346_8	644966.Tmar_1664	3.516e-61	220.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,24GE9@186801|Clostridia	186801|Clostridia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YYD2_k127_6209346_0	880073.Calab_0665	4.885e-266	844.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2NNT2@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	CP_0743	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YYD2_k127_6209346_6	861299.J421_3598	7.39e-92	313.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YYD2_k127_6209346_3	485913.Krac_11170	2.251e-121	397.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
YYD2_k127_6209346_5	880073.Calab_0664	1.255e-110	375.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD2_k127_6209346_4	518766.Rmar_2195	1.184e-114	378.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1FIV9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YYD2_k127_6209346_9	867903.ThesuDRAFT_00167	3.569e-39	153.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WCIP@538999|Clostridiales incertae sedis	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YYD2_k127_6209346_10	880073.Calab_2038	1.332e-09	65.0	2DEXR@1|root,2ZPPS@2|Bacteria,2NRXB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6209346_2	580340.Tlie_0854	1.197e-147	487.0	COG2804@1|root,COG2804@2|Bacteria,3T9WP@508458|Synergistetes	508458|Synergistetes	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YYD2_k127_6209346_7	497964.CfE428DRAFT_3562	8.562e-87	302.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YYD2_k127_6209346_11	927677.ALVU02000001_gene2887	1.263e-06	58.0	COG4968@1|root,COG4968@2|Bacteria,1GHF2@1117|Cyanobacteria,1H5WA@1142|Synechocystis	1117|Cyanobacteria	NU	Pfam:N_methyl_2	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_GH
YYD2_k127_6209346_12	1209989.TepiRe1_1527	2.353e-05	55.0	COG4966@1|root,COG4966@2|Bacteria,1UF09@1239|Firmicutes,25K0H@186801|Clostridia,42IS4@68295|Thermoanaerobacterales	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
YYD2_k127_6213178_2	983917.RGE_36580	2.902e-89	311.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VIVJ@28216|Betaproteobacteria,1KMWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
YYD2_k127_6213178_0	404589.Anae109_0939	9.038e-287	921.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
YYD2_k127_6213178_1	404589.Anae109_0938	4.781e-94	317.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
YYD2_k127_6213178_3	404589.Anae109_0937	3.325e-71	250.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
YYD2_k127_6218756_1	937777.Deipe_0706	2.293e-06	52.0	COG0448@1|root,COG0448@2|Bacteria,1WMAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Nucleotidyl transferase	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD2_k127_6218756_0	1499967.BAYZ01000068_gene1973	1.713e-127	422.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27,2.7.7.91	ko:K00975,ko:K20427	ko00500,ko00520,ko00525,ko01100,ko01110,ko01130,ko02026,map00500,map00520,map00525,map01100,map01110,map01130,map02026	M00565,M00814	R00948,R11237,R11246,R11402	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
YYD2_k127_6226825_1	717773.Thicy_1516	5.049e-08	61.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,460F8@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
YYD2_k127_6226825_2	880073.Calab_0631	0.0002614	54.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y,YceI
YYD2_k127_6226825_0	525904.Tter_0464	4.007e-96	332.0	COG0405@1|root,COG0405@2|Bacteria,2NP14@2323|unclassified Bacteria	2|Bacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YYD2_k127_6228817_2	641491.DND132_2360	1.726e-14	75.0	COG1744@1|root,COG1744@2|Bacteria,1NGHH@1224|Proteobacteria,42RBQ@68525|delta/epsilon subdivisions,2WN1W@28221|Deltaproteobacteria,2MBUC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
YYD2_k127_6228817_0	1116232.AHBF01000004_gene1006	6.307e-106	364.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
YYD2_k127_6228817_1	502025.Hoch_6737	3.119e-38	157.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42RQG@68525|delta/epsilon subdivisions,2WNDT@28221|Deltaproteobacteria,2YZU8@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
YYD2_k127_6232351_0	644966.Tmar_0757	9.016e-174	552.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
YYD2_k127_6232351_2	518766.Rmar_2679	1.099e-121	413.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1FIW7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD2_k127_6232351_4	935948.KE386494_gene822	1.048e-26	117.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YYD2_k127_6232351_3	68223.JNZY01000023_gene6160	3.032e-27	122.0	COG0009@1|root,COG0009@2|Bacteria,2GN4J@201174|Actinobacteria	201174|Actinobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YYD2_k127_6232351_1	251221.35211608	5.68e-140	455.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YYD2_k127_6235174_0	635013.TherJR_1781	8.842e-164	530.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
YYD2_k127_6235174_3	1288079.AUKN01000009_gene959	3.581e-51	188.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YYD2_k127_6235174_2	290318.Cvib_1105	8.276e-59	220.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1FDJQ@1090|Chlorobi	1090|Chlorobi	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YYD2_k127_6235174_4	215803.DB30_6565	2.014e-05	52.0	COG2165@1|root,COG2165@2|Bacteria,1QX8K@1224|Proteobacteria,43C1Q@68525|delta/epsilon subdivisions,2X7CB@28221|Deltaproteobacteria,2Z3FC@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilin PilA	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,Pilin_PilA
YYD2_k127_6235174_1	398767.Glov_3251	3.084e-121	404.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,43U60@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YYD2_k127_6237473_3	909663.KI867150_gene2169	7.668e-97	333.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria,2MQ9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	MOFRL family	Glyctk	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
YYD2_k127_6237473_1	909663.KI867151_gene3000	2.089e-189	600.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MQYT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
YYD2_k127_6237473_2	909663.KI867151_gene3008	4.894e-173	552.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
YYD2_k127_6237473_4	909663.KI867151_gene3009	4.942e-60	215.0	COG0668@1|root,COG0668@2|Bacteria,1RK3V@1224|Proteobacteria,437YT@68525|delta/epsilon subdivisions,2X9SI@28221|Deltaproteobacteria,2MSF0@213462|Syntrophobacterales	2|Bacteria	M	transmembrane transport	ygxB	-	-	-	-	-	-	-	-	-	-	-	TM_helix
YYD2_k127_6237473_0	502025.Hoch_4095	1.445e-289	904.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2Z34A@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YYD2_k127_6240282_0	1120797.KB908260_gene4073	4.973e-125	435.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	pknK_2	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
YYD2_k127_6269632_7	1121957.ATVL01000014_gene1459	5.626e-58	220.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_11	518766.Rmar_1071	9.568e-08	64.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
YYD2_k127_6269632_5	37659.JNLN01000001_gene1577	2.005e-87	304.0	COG1670@1|root,COG1680@1|root,COG1670@2|Bacteria,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Gram_pos_anchor
YYD2_k127_6269632_6	1379698.RBG1_1C00001G0112	3.092e-64	238.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_4	1379698.RBG1_1C00001G0113	2.553e-93	314.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_8	1379698.RBG1_1C00001G0114	2.267e-56	204.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_3	1379698.RBG1_1C00001G0115	4.248e-103	347.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_2	1379698.RBG1_1C00001G0120	3.193e-125	414.0	28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_0	1379698.RBG1_1C00001G0122	2.395e-255	810.0	COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria	2|Bacteria	G	MutL protein	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
YYD2_k127_6269632_9	1379698.RBG1_1C00001G0125	4.606e-17	86.0	2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_10	1379698.RBG1_1C00001G0126	1.88e-12	75.0	2C451@1|root,2ZRAU@2|Bacteria,2NS2X@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6269632_1	401526.TcarDRAFT_2680	8.408e-140	452.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4H2E4@909932|Negativicutes	909932|Negativicutes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
YYD2_k127_6269661_0	1313301.AUGC01000004_gene2198	4.402e-137	451.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes	976|Bacteroidetes	E	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
YYD2_k127_6269661_2	935863.AWZR01000012_gene2548	1.863e-38	163.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1X738@135614|Xanthomonadales	135614|Xanthomonadales	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YYD2_k127_6269661_3	103733.JNYO01000052_gene5991	8.983e-06	57.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E0I8@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,BTAD,NB-ARC,TPR_12,TPR_8,Trans_reg_C
YYD2_k127_6269661_1	404589.Anae109_2419	6.14e-135	445.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_6277183_0	1047013.AQSP01000140_gene2536	3.919e-93	321.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_6277183_2	1047013.AQSP01000140_gene2537	9.726e-91	313.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD2_k127_6277183_1	945713.IALB_1699	2.449e-92	311.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_6277183_3	1379698.RBG1_1C00001G1364	3.652e-72	262.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YYD2_k127_6277183_4	497964.CfE428DRAFT_5939	1.026e-08	66.0	COG1538@1|root,COG1538@2|Bacteria,46T0P@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD2_k127_6281377_0	1499967.BAYZ01000065_gene6111	1.2e-62	221.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
YYD2_k127_6281377_1	1303518.CCALI_00674	3.066e-48	181.0	COG0503@1|root,COG0503@2|Bacteria	2|Bacteria	F	purine ribonucleoside salvage	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	PRTase_2,Pribosyltran,TRSP
YYD2_k127_6281377_2	457570.Nther_1838	2.061e-12	78.0	COG0640@1|root,COG2309@1|root,COG0640@2|Bacteria,COG2309@2|Bacteria,1VC7T@1239|Firmicutes,24PC2@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
YYD2_k127_6285703_0	1192034.CAP_5366	7.472e-116	382.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales	28221|Deltaproteobacteria	E	synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
YYD2_k127_6285703_4	525904.Tter_0083	3.063e-11	73.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8
YYD2_k127_6285703_3	84531.JMTZ01000018_gene3940	1.486e-16	94.0	2B2WH@1|root,31VH2@2|Bacteria,1QCMM@1224|Proteobacteria,1T8D0@1236|Gammaproteobacteria,1XAGE@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6285703_1	998674.ATTE01000001_gene2961	6.579e-80	273.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,1RNSP@1236|Gammaproteobacteria,46334@72273|Thiotrichales	72273|Thiotrichales	L	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YYD2_k127_6285703_2	1408473.JHXO01000001_gene1949	8.889e-46	178.0	COG3104@1|root,COG3104@2|Bacteria,4NIIT@976|Bacteroidetes,2FR16@200643|Bacteroidia	976|Bacteroidetes	E	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_6286760_7	246194.CHY_2625	6.288e-28	124.0	COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,42FT7@68295|Thermoanaerobacterales	186801|Clostridia	M	G5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
YYD2_k127_6286760_9	1048983.EL17_15775	2.053e-15	82.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47SCM@768503|Cytophagia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD2_k127_6286760_6	760192.Halhy_0782	5.251e-33	147.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,1IPME@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YYD2_k127_6286760_0	886293.Sinac_7194	4.717e-95	327.0	COG0626@1|root,COG0626@2|Bacteria,2IYKV@203682|Planctomycetes	203682|Planctomycetes	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
YYD2_k127_6286760_2	472759.Nhal_3774	8.72e-64	238.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1WWFG@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
YYD2_k127_6286760_4	383372.Rcas_3070	2.068e-48	188.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YYD2_k127_6286760_10	243231.GSU0622	6.85e-12	79.0	COG0457@1|root,COG0457@2|Bacteria	243231.GSU0622|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_6286760_3	994479.GL877878_gene979	5.298e-54	214.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4E1NP@85010|Pseudonocardiales	201174|Actinobacteria	Q	naringenin-chalcone synthase	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
YYD2_k127_6286760_5	1089550.ATTH01000001_gene332	5.828e-46	183.0	COG0654@1|root,COG0654@2|Bacteria,4PM2V@976|Bacteroidetes,1FJWJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
YYD2_k127_6286760_8	330214.NIDE1118	3.405e-23	116.0	COG4783@1|root,COG4783@2|Bacteria,3J193@40117|Nitrospirae	40117|Nitrospirae	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD2_k127_6286760_1	289376.THEYE_A1970	2.229e-71	247.0	COG3264@1|root,COG3264@2|Bacteria,3J0R7@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
YYD2_k127_6306171_1	1089553.Tph_c08010	5.237e-74	266.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1TT8V@1239|Firmicutes,24BFH@186801|Clostridia,42ETS@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
YYD2_k127_6306171_0	1163617.SCD_n02012	2.439e-115	378.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD2_k127_6309756_1	215803.DB30_5907	4.224e-10	61.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_6309756_2	215803.DB30_5907	4.769e-10	67.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_6309756_0	795359.TOPB45_0363	3.626e-44	176.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
YYD2_k127_632712_2	595460.RRSWK_01118	5.06e-09	63.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD2_k127_632712_1	589865.DaAHT2_1706	8.135e-25	115.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQ9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD2_k127_632712_0	443144.GM21_4097	7.86e-39	164.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42S0N@68525|delta/epsilon subdivisions,2WN9X@28221|Deltaproteobacteria,43U96@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
YYD2_k127_632935_3	880073.Calab_3681	7.415e-105	377.0	COG3051@1|root,COG3051@2|Bacteria,2NP8D@2323|unclassified Bacteria	2|Bacteria	C	Citrate lyase, alpha subunit (CitF)	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
YYD2_k127_632935_1	945713.IALB_1147	8.269e-142	460.0	COG2301@1|root,COG3052@1|root,COG2301@2|Bacteria,COG3052@2|Bacteria	2|Bacteria	C	prosthetic group binding	citD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	4.1.3.25,4.1.3.34	ko:K01644,ko:K01646,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	ACP,HpcH_HpaI
YYD2_k127_632935_0	945713.IALB_1153	1.394e-191	604.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	dlpA	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh,MoCF_biosynth,RraA-like
YYD2_k127_632935_5	1343158.SACS_1572	1.441e-14	83.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2JSJ9@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD2_k127_632935_2	1382359.JIAL01000001_gene2095	9.469e-135	445.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_632935_4	671143.DAMO_1877	8.466e-76	280.0	COG5000@1|root,COG5000@2|Bacteria,2NQZA@2323|unclassified Bacteria	2|Bacteria	T	Multi-sensor signal transduction histidine kinase	ntrB	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
YYD2_k127_6374529_3	561175.KB894104_gene1192	3.396e-13	74.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
YYD2_k127_6374529_1	714943.Mucpa_3108	7.25e-52	192.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
YYD2_k127_6374529_0	1379698.RBG1_1C00001G0364	3.396e-130	426.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YYD2_k127_6374529_4	446462.Amir_4959	4.302e-05	56.0	COG1807@1|root,COG1807@2|Bacteria,2I3WA@201174|Actinobacteria,4EE5H@85010|Pseudonocardiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT
YYD2_k127_6374529_2	1449353.JQMQ01000005_gene987	4.814e-44	175.0	COG0842@1|root,COG0842@2|Bacteria,2HNB6@201174|Actinobacteria,2NHZ8@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
YYD2_k127_6379499_1	489825.LYNGBM3L_22490	1.473e-54	200.0	COG0578@1|root,COG0578@2|Bacteria,1G1T3@1117|Cyanobacteria,1H86N@1150|Oscillatoriales	1117|Cyanobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
YYD2_k127_6379499_0	1499967.BAYZ01000123_gene2530	1.221e-126	426.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YYD2_k127_6379499_2	644282.Deba_0617	2.19e-38	155.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQ4T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD2_k127_6391478_2	1396418.BATQ01000166_gene1865	8.327e-06	50.0	COG4805@1|root,COG4805@2|Bacteria,46XD2@74201|Verrucomicrobia,2IVH8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YYD2_k127_6391478_1	1125863.JAFN01000001_gene529	1.73e-106	357.0	COG0859@1|root,COG0859@2|Bacteria,1NCZT@1224|Proteobacteria,42VSS@68525|delta/epsilon subdivisions,2WS4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD2_k127_6391478_0	1379698.RBG1_1C00001G1033	4.58e-191	616.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD2_k127_6410996_0	886293.Sinac_6888	6.951e-72	252.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YYD2_k127_6410996_1	264462.Bd3044	1.447e-15	81.0	COG2036@1|root,COG2036@2|Bacteria,1N3S6@1224|Proteobacteria,42UYX@68525|delta/epsilon subdivisions,2MU6K@213481|Bdellovibrionales,2WQE4@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_649864_0	1191523.MROS_2798	1.33e-286	918.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
YYD2_k127_649864_1	1499967.BAYZ01000119_gene3216	1.321e-199	638.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
YYD2_k127_649864_2	671143.DAMO_1514	7.949e-62	222.0	COG1806@1|root,COG1806@2|Bacteria,2NRN6@2323|unclassified Bacteria	2|Bacteria	S	Kinase/pyrophosphorylase	yqfL	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
YYD2_k127_658333_2	204669.Acid345_2605	1.531e-25	122.0	COG1913@1|root,COG1913@2|Bacteria,3Y880@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
YYD2_k127_658333_0	945713.IALB_2429	1.861e-156	510.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD2_k127_658333_1	290397.Adeh_3383	4.231e-38	149.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,2Z0GM@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
YYD2_k127_66036_2	1408823.AXUS01000005_gene2501	7.32e-35	134.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,25RCD@186804|Peptostreptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
YYD2_k127_66036_1	1379698.RBG1_1C00001G1495	8.254e-125	411.0	COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
YYD2_k127_66036_0	1121468.AUBR01000026_gene2952	6.96e-127	432.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,42F1H@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YYD2_k127_66036_3	880073.Calab_3481	1.246e-08	68.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
YYD2_k127_662604_1	404589.Anae109_2479	3.568e-13	70.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD2_k127_662604_2	1451261.AS96_14240	4.643e-12	70.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD2_k127_662604_0	670292.JH26_15675	6.685e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,1NQ71@1224|Proteobacteria,2UQI7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratrico peptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_5
YYD2_k127_662604_3	1121335.Clst_0120	5.823e-06	58.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD2_k127_691608_0	349124.Hhal_0037	3.107e-28	128.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD2_k127_693438_0	1128421.JAGA01000002_gene62	1.33e-46	172.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD2_k127_693438_2	1089550.ATTH01000002_gene18	1.016e-05	57.0	COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria,4PHV3@976|Bacteroidetes,1FK10@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_693438_1	555088.DealDRAFT_0635	5.872e-25	119.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,42JQK@68298|Syntrophomonadaceae	186801|Clostridia	L	Belongs to the helicase family. AddB RexB type 1 subfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
YYD2_k127_697669_1	1173020.Cha6605_2607	7.807e-116	386.0	COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
YYD2_k127_697669_0	485913.Krac_4915	3.334e-165	531.0	COG1249@1|root,COG1249@2|Bacteria,2G5VW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	merA	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD2_k127_697669_2	1210884.HG799462_gene8785	1.218e-09	61.0	COG0693@1|root,COG0693@2|Bacteria,2IYYE@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YYD2_k127_757591_1	1125863.JAFN01000001_gene2541	1.825e-116	424.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria	1224|Proteobacteria	C	Belongs to the citrate synthase family	gltA	GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0026,iYL1228.KPN_00727	Citrate_synt
YYD2_k127_757591_0	880073.Calab_0527	5.365e-295	962.0	COG0454@1|root,COG1022@1|root,COG0456@2|Bacteria,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	2.5.1.16,6.2.1.3	ko:K00797,ko:K01897	ko00061,ko00071,ko00270,ko00330,ko00410,ko00480,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00270,map00330,map00410,map00480,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00034,M00086,M00133	R01280,R01920,R02869,R08359	RC00004,RC00014,RC00021,RC00053	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
YYD2_k127_757591_2	1121926.AXWO01000001_gene3783	2.299e-19	94.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4EXTR@85014|Glycomycetales	201174|Actinobacteria	G	Phosphofructokinase	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
YYD2_k127_759491_3	768671.ThimaDRAFT_2780	0.0001109	55.0	COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,1RSFQ@1236|Gammaproteobacteria,1WWNG@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_16
YYD2_k127_759491_1	1499967.BAYZ01000019_gene6266	2.978e-55	210.0	COG2304@1|root,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
YYD2_k127_759491_0	880073.Calab_2474	1.939e-88	309.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
YYD2_k127_759491_2	1242864.D187_006461	2.302e-06	55.0	2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_77966_3	1267533.KB906735_gene4549	3.706e-20	96.0	COG0515@1|root,COG0515@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
YYD2_k127_77966_0	62928.azo1320	4.212e-114	379.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,2KZS6@206389|Rhodocyclales	206389|Rhodocyclales	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
YYD2_k127_77966_1	1496688.ER33_00820	9.247e-112	370.0	COG0500@1|root,COG2226@2|Bacteria,1G1WF@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
YYD2_k127_77966_2	1121481.AUAS01000006_gene877	3.255e-47	184.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
YYD2_k127_795689_0	880073.Calab_1833	5.027e-132	429.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,2NNYT@2323|unclassified Bacteria	2|Bacteria	E	Aconitase family (aconitate hydratase)	leuD	-	4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01704,ko:K01705	ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD2_k127_795689_1	460265.Mnod_5853	9.655e-80	273.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,1JSFG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
YYD2_k127_809952_1	1121472.AQWN01000001_gene137	6.051e-113	373.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
YYD2_k127_809952_14	1267535.KB906767_gene3291	1.112e-08	60.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
YYD2_k127_809952_11	479434.Sthe_1258	6.507e-22	101.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi,27YJU@189775|Thermomicrobia	189775|Thermomicrobia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YYD2_k127_809952_5	338966.Ppro_0966	3.935e-60	227.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,43UI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
YYD2_k127_809952_7	1323663.AROI01000017_gene642	6.762e-54	203.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
YYD2_k127_809952_9	370438.PTH_1274	5.324e-31	124.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,262DU@186807|Peptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YYD2_k127_809952_0	1379698.RBG1_1C00001G1160	1.914e-248	784.0	COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria	2|Bacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YYD2_k127_809952_2	1379698.RBG1_1C00001G1161	2.272e-100	342.0	COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD2_k127_809952_8	985665.HPL003_18425	5.278e-45	169.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,26WU8@186822|Paenibacillaceae	91061|Bacilli	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
YYD2_k127_809952_6	1379698.RBG1_1C00001G1249	5.068e-54	200.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
YYD2_k127_809952_3	1125863.JAFN01000001_gene1126	2.59e-81	282.0	COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_809952_10	1292034.OR37_02443	2.601e-24	114.0	COG1596@1|root,COG1596@2|Bacteria,1RDXY@1224|Proteobacteria,2U7HK@28211|Alphaproteobacteria,2KGGC@204458|Caulobacterales	204458|Caulobacterales	M	PFAM polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YYD2_k127_809952_13	1232410.KI421418_gene2330	2.759e-16	92.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WN1C@28221|Deltaproteobacteria,43S7E@69541|Desulfuromonadales	28221|Deltaproteobacteria	DM	Chain length determinant protein	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
YYD2_k127_809952_4	316067.Geob_2237	2.837e-63	227.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	SMART AAA ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
YYD2_k127_809952_12	1121448.DGI_1959	8.222e-20	98.0	COG0489@1|root,COG0489@2|Bacteria,1MZ64@1224|Proteobacteria,432Z4@68525|delta/epsilon subdivisions,2WXW1@28221|Deltaproteobacteria,2MDQQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	AAA domain	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31
YYD2_k127_810457_0	886293.Sinac_2075	1.982e-80	278.0	COG0697@1|root,COG0697@2|Bacteria,2J1H6@203682|Planctomycetes	203682|Planctomycetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD2_k127_810457_1	880073.Calab_2081	6.436e-16	92.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
YYD2_k127_810457_2	391625.PPSIR1_33339	3.04e-09	61.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD2_k127_813393_2	382464.ABSI01000011_gene3052	4.341e-34	132.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,2IU3F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YYD2_k127_813393_0	479434.Sthe_2364	1.049e-119	405.0	COG0076@1|root,COG0076@2|Bacteria,2G8Q9@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD2_k127_813393_1	215803.DB30_5797	3.765e-85	299.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,438ST@68525|delta/epsilon subdivisions,2X9CS@28221|Deltaproteobacteria,2YXPE@29|Myxococcales	28221|Deltaproteobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_81615_4	314278.NB231_05936	2.377e-05	55.0	291NB@1|root,2ZP8I@2|Bacteria,1P5ZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YYD2_k127_81615_1	338963.Pcar_0607	1.851e-41	162.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,43UPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YYD2_k127_81615_0	316067.Geob_1587	7.837e-118	384.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43TNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
YYD2_k127_81615_3	58344.JOEL01000004_gene7082	5.601e-11	73.0	COG2104@1|root,COG2104@2|Bacteria,2GQKM@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD2_k127_81615_2	118163.Ple7327_2078	4.067e-32	134.0	COG0665@1|root,COG2022@1|root,COG0665@2|Bacteria,COG2022@2|Bacteria,1FZYU@1117|Cyanobacteria,3VIRP@52604|Pleurocapsales	1117|Cyanobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	DAO,ThiG
YYD2_k127_816624_2	903818.KI912268_gene1040	1.041e-34	153.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DUF4388,DnaJ
YYD2_k127_816624_4	338963.Pcar_0504	4.51e-10	67.0	2BP69@1|root,32HXD@2|Bacteria,1Q1KM@1224|Proteobacteria,437BM@68525|delta/epsilon subdivisions,2X2GS@28221|Deltaproteobacteria,43VCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_816624_0	485913.Krac_7836	2.014e-156	502.0	COG1960@1|root,COG1960@2|Bacteria,2G7JH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD2_k127_816624_1	767817.Desgi_1968	3.046e-56	207.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes	1239|Firmicutes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
YYD2_k127_816624_3	386415.NT01CX_0538	2.134e-20	91.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,36DVG@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA2	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD2_k127_822084_3	861299.J421_0956	1.675e-38	156.0	COG0583@1|root,COG0583@2|Bacteria,1ZU5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
YYD2_k127_822084_0	861299.J421_3601	3.553e-208	660.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
YYD2_k127_822084_1	1462527.CCDM010000006_gene4704	1.048e-68	247.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,23MKV@182709|Oceanobacillus	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YYD2_k127_822084_2	1379698.RBG1_1C00001G1514	1.807e-45	178.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
YYD2_k127_826365_2	1089551.KE386572_gene1955	5.533e-26	116.0	COG3119@1|root,COG3119@2|Bacteria,1MYHH@1224|Proteobacteria,2UA67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YYD2_k127_826365_1	1379698.RBG1_1C00001G1318	2.634e-46	185.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD2_k127_826365_0	637905.SVI_1560	9.481e-64	239.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4983,FIVAR,Hemopexin,Laminin_G_3,PA14,Phosphodiest
YYD2_k127_827398_0	504472.Slin_1834	1.997e-315	992.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47K02@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD2_k127_827398_1	102232.GLO73106DRAFT_00005840	9.456e-115	382.0	COG3386@1|root,COG3386@2|Bacteria,1G1H9@1117|Cyanobacteria	1117|Cyanobacteria	G	Major royal jelly protein	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
YYD2_k127_827398_2	861299.J421_1598	1.549e-61	216.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.metX	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YYD2_k127_833463_1	1463856.JOHY01000030_gene2830	1.153e-13	83.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria	201174|Actinobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YYD2_k127_833463_0	525904.Tter_2416	2.872e-95	330.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
YYD2_k127_839276_3	1125863.JAFN01000001_gene3521	2.074e-11	73.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
YYD2_k127_839276_0	1278073.MYSTI_06338	6.21e-82	293.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
YYD2_k127_839276_1	498761.HM1_0465	3.375e-76	264.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
YYD2_k127_839276_2	1307759.JOMJ01000003_gene2150	1.947e-23	106.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MB1P@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
YYD2_k127_840678_0	204669.Acid345_2395	2.334e-85	309.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
YYD2_k127_847599_0	1254432.SCE1572_37995	8.972e-61	213.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,439P5@68525|delta/epsilon subdivisions,2X50M@28221|Deltaproteobacteria,2YZXZ@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD2_k127_847599_2	1403819.BATR01000130_gene4660	2.202e-17	92.0	COG3794@1|root,COG3794@2|Bacteria,46SUG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD2_k127_847599_1	572477.Alvin_1750	6.441e-35	154.0	COG0642@1|root,COG3437@1|root,COG5000@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1T4M1@1236|Gammaproteobacteria,1WYGE@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
YYD2_k127_849203_2	1237149.C900_05249	2.02e-70	248.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
YYD2_k127_849203_8	1265505.ATUG01000002_gene1413	2.062e-21	107.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MMVB@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YYD2_k127_849203_4	1265505.ATUG01000002_gene1414	5.181e-38	154.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,42RSB@68525|delta/epsilon subdivisions,2X6V6@28221|Deltaproteobacteria,2MMG6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YYD2_k127_849203_1	1242864.D187_010275	1.167e-77	283.0	COG0204@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
YYD2_k127_849203_9	1160137.KB907307_gene352	0.0005751	51.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	pfaA	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
YYD2_k127_849203_7	38727.Pavir.Aa01091.1.p	3.879e-30	138.0	COG1024@1|root,KOG1679@2759|Eukaryota,37RGM@33090|Viridiplantae,3GG5X@35493|Streptophyta,3KVGY@4447|Liliopsida,3I2C5@38820|Poales	35493|Streptophyta	I	Belongs to the enoyl-CoA hydratase isomerase family	-	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.18	ko:K05607	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YYD2_k127_849203_3	1121017.AUFG01000032_gene404	5.833e-68	252.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	PPA2234	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
YYD2_k127_849203_0	1123242.JH636435_gene2291	2.405e-135	446.0	COG2327@1|root,COG2327@2|Bacteria	2|Bacteria	S	slime layer polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
YYD2_k127_849203_6	1283299.AUKG01000001_gene2474	9.142e-31	139.0	COG3320@1|root,COG3320@2|Bacteria,2I9YC@201174|Actinobacteria,4CS8U@84995|Rubrobacteria	84995|Rubrobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
YYD2_k127_849203_5	502025.Hoch_3248	8.112e-31	131.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
YYD2_k127_865647_0	880073.Calab_3450	5.8e-127	433.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
YYD2_k127_869233_0	1210884.HG799466_gene12575	2.463e-10	71.0	COG0457@1|root,COG0457@2|Bacteria,2J039@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_872177_0	696281.Desru_2798	1.234e-170	546.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,2614W@186807|Peptococcaceae	186801|Clostridia	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD2_k127_872177_1	880073.Calab_2424	2.815e-43	177.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
YYD2_k127_872177_3	908937.Prede_1557	6.928e-06	55.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
YYD2_k127_872177_2	1125863.JAFN01000001_gene268	8.546e-09	65.0	COG0848@1|root,COG0848@2|Bacteria,1NN40@1224|Proteobacteria,42XMQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YYD2_k127_884389_13	404589.Anae109_0495	4.103e-44	162.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QU3@68525|delta/epsilon subdivisions,2WMTF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD2_k127_884389_17	215803.DB30_6611	7.613e-36	145.0	COG1695@1|root,COG1695@2|Bacteria,1RFWJ@1224|Proteobacteria,42W87@68525|delta/epsilon subdivisions,2WR6P@28221|Deltaproteobacteria,2YX8V@29|Myxococcales	28221|Deltaproteobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
YYD2_k127_884389_5	1121468.AUBR01000016_gene2303	2.64e-101	349.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
YYD2_k127_884389_7	401526.TcarDRAFT_0885	7.752e-87	293.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4H223@909932|Negativicutes	909932|Negativicutes	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
YYD2_k127_884389_6	1117379.BABA_05681	1.204e-88	314.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,1ZB0Q@1386|Bacillus	91061|Bacilli	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YYD2_k127_884389_2	1379698.RBG1_1C00001G1349	1.407e-112	373.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YYD2_k127_884389_3	1379698.RBG1_1C00001G1350	2.218e-111	367.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YYD2_k127_884389_1	1379698.RBG1_1C00001G1351	3.38e-136	444.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YYD2_k127_884389_0	868864.Dester_0191	3.225e-225	717.0	COG0480@1|root,COG0480@2|Bacteria,2G3NW@200783|Aquificae	200783|Aquificae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD2_k127_884389_25	203122.Sde_2615	3.333e-06	58.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,1RGHP@1224|Proteobacteria,1S54W@1236|Gammaproteobacteria,468YG@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
YYD2_k127_884389_11	349161.Dred_0478	5.912e-52	196.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,265QT@186807|Peptococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	PaaY	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
YYD2_k127_884389_18	439235.Dalk_2411	9.945e-35	144.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MJT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
YYD2_k127_884389_24	880073.Calab_2464	2.021e-06	60.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Beta-lactamase,DUF3471,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
YYD2_k127_884389_23	1294273.roselon_00969	3.473e-10	72.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidylprolyl isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
YYD2_k127_884389_15	880073.Calab_2408	2.249e-37	146.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YYD2_k127_884389_20	1120973.AQXL01000133_gene1807	7.167e-25	105.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,27AAM@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YYD2_k127_884389_22	671143.DAMO_0511	2.618e-17	90.0	COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria	2|Bacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YYD2_k127_884389_21	1499684.CCNP01000010_gene103	2.913e-19	93.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YYD2_k127_884389_14	1121468.AUBR01000106_gene3110	9.792e-43	164.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,42GBC@68295|Thermoanaerobacterales	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YYD2_k127_884389_16	373903.Hore_21220	2.659e-36	150.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WBPT@53433|Halanaerobiales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YYD2_k127_884389_4	1121468.AUBR01000004_gene198	3.7e-106	357.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,42EXR@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YYD2_k127_884389_19	264462.Bd2801	2.319e-25	109.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2MU0J@213481|Bdellovibrionales,2WQYK@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
YYD2_k127_884389_10	370438.PTH_0096	4.181e-54	211.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,261HE@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_884389_8	635013.TherJR_2839	9.055e-76	268.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,2621I@186807|Peptococcaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
YYD2_k127_884389_9	335543.Sfum_2262	1.982e-56	212.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WKQ9@28221|Deltaproteobacteria,2MRJ6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YYD2_k127_884389_12	635013.TherJR_1904	5.277e-48	181.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,260FP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD2_k127_885007_2	1121428.DESHY_110132___1	1.212e-36	143.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25ZXR@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YYD2_k127_885007_1	1303518.CCALI_01793	1.414e-44	169.0	COG0194@1|root,COG0194@2|Bacteria	2|Bacteria	F	guanylate kinase activity	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YYD2_k127_885007_0	370438.PTH_1797	7.107e-67	241.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,2617V@186807|Peptococcaceae	186801|Clostridia	S	PFAM YicC-like family, N-terminal region	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
YYD2_k127_885007_3	671143.DAMO_0478	2.01e-27	125.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	vncS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3	ko:K07315,ko:K07641,ko:K10819,ko:K13924	ko02020,ko02030,map02020,map02030	M00449,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YYD2_k127_897415_1	351160.RCIX757	1.399e-48	181.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,2NASJ@224756|Methanomicrobia	224756|Methanomicrobia	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
YYD2_k127_897415_2	448385.sce1953	1.17e-33	150.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YYD2_k127_897415_6	880073.Calab_2081	0.000331	54.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
YYD2_k127_897415_5	35754.JNYJ01000110_gene4626	1.756e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,2GXH4@201174|Actinobacteria,4DFZB@85008|Micromonosporales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2
YYD2_k127_897415_4	317013.NY99_12840	1.756e-07	64.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1SCVJ@1236|Gammaproteobacteria,1X7BK@135614|Xanthomonadales	135614|Xanthomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD2_k127_897415_3	459349.CLOAM0442	2.753e-10	73.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
YYD2_k127_897415_0	459349.CLOAM1312	1.664e-65	245.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD2_k127_923608_0	1121377.KB906424_gene3959	2.452e-99	352.0	COG2771@1|root,COG3903@1|root,COG2771@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,BTAD,DUF4019,GerE,NB-ARC,TPR_12
YYD2_k127_924676_2	886293.Sinac_5397	5.493e-20	93.0	COG1225@1|root,COG1225@2|Bacteria,2IZIQ@203682|Planctomycetes	203682|Planctomycetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD2_k127_924676_1	575540.Isop_3564	1.281e-21	104.0	COG1381@1|root,COG1381@2|Bacteria,2IZU9@203682|Planctomycetes	203682|Planctomycetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
YYD2_k127_924676_0	309803.CTN_0328	2.104e-22	102.0	COG2876@1|root,COG2876@2|Bacteria,2GCMH@200918|Thermotogae	200918|Thermotogae	E	PFAM DAHP synthetase I	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YYD2_k127_929952_1	378806.STAUR_3879	1.975e-64	226.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
YYD2_k127_929952_0	1254432.SCE1572_02795	5.152e-126	422.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD2_k127_929952_2	234267.Acid_3455	5.082e-22	108.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD2_k127_929952_3	234267.Acid_3454	7.623e-22	108.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	57723|Acidobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
YYD2_k127_930923_5	66429.JOFL01000006_gene2122	9.432e-13	81.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
YYD2_k127_930923_1	204669.Acid345_1822	5.497e-173	553.0	COG4992@1|root,COG4992@2|Bacteria,3Y40B@57723|Acidobacteria,2JHYT@204432|Acidobacteriia	204432|Acidobacteriia	E	TIGRFAM ornithine aminotransferase	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
YYD2_k127_930923_3	903818.KI912268_gene2010	1.502e-72	271.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,CHASE8,GAF_2,HATPase_c,HisKA,Hpt,PAS_8,PAS_9,Response_reg
YYD2_k127_930923_0	264198.Reut_B4987	1.351e-173	558.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD2_k127_930923_4	1380394.JADL01000014_gene241	6.286e-20	104.0	COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2UKCD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	-
YYD2_k127_930923_2	243233.MCA2067	4.525e-86	294.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XDJM@135618|Methylococcales	1236|Gammaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YYD2_k127_933158_1	1379270.AUXF01000004_gene3078	1.12e-75	270.0	COG0182@1|root,COG0182@2|Bacteria,1ZT28@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YYD2_k127_933158_2	555079.Toce_0738	1.283e-46	179.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
YYD2_k127_933158_3	1121346.KB899811_gene1646	4.402e-46	171.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,26XEB@186822|Paenibacillaceae	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YYD2_k127_933158_0	1173021.ALWA01000019_gene346	3.957e-175	576.0	COG0317@1|root,COG0317@2|Bacteria,1G0KC@1117|Cyanobacteria	1117|Cyanobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YYD2_k127_933158_4	880070.Cycma_1083	5.531e-10	64.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YYD2_k127_93607_3	1142394.PSMK_16050	5.03e-13	79.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,Peptidase_M42
YYD2_k127_93607_2	330214.NIDE0521	2.055e-60	222.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
YYD2_k127_93607_1	177437.HRM2_09660	3.56e-70	264.0	COG0697@1|root,COG2371@1|root,COG0697@2|Bacteria,COG2371@2|Bacteria,1N3FA@1224|Proteobacteria,42RW0@68525|delta/epsilon subdivisions,2WNEH@28221|Deltaproteobacteria,2MMWS@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD2_k127_93607_0	1379698.RBG1_1C00001G0675	2.013e-73	261.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
YYD2_k127_948900_2	446466.Cfla_3491	1.652e-09	62.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD2_k127_948900_1	42256.RradSPS_2320	1.34e-65	235.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CTQB@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YYD2_k127_948900_0	909663.KI867150_gene1810	5.387e-110	375.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2MRF6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YYD2_k127_948901_5	671143.DAMO_1863	1.383e-13	72.0	COG0291@1|root,COG0291@2|Bacteria,2NQ3J@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YYD2_k127_948901_4	1232683.ADIMK_2664	8.33e-33	134.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,466ZJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YYD2_k127_948901_6	498761.HM1_1799	0.0001978	49.0	COG3027@1|root,COG3027@2|Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
YYD2_k127_948901_0	1121430.JMLG01000001_gene2105	2.454e-143	472.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25ZZN@186807|Peptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
YYD2_k127_948901_1	1195236.CTER_2342	2.03e-93	315.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,3WHB0@541000|Ruminococcaceae	186801|Clostridia	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
YYD2_k127_948901_3	886293.Sinac_3010	5.887e-53	195.0	COG0190@1|root,COG0190@2|Bacteria,2IXS4@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YYD2_k127_948901_2	187272.Mlg_0693	2.468e-93	333.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YYD2_k127_952187_0	107636.JQNK01000008_gene4265	3.072e-87	292.0	COG1309@1|root,COG1309@2|Bacteria,1NBMY@1224|Proteobacteria,2UX53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YYD2_k127_952187_2	1268072.PSAB_08730	1.093e-31	140.0	2AKFW@1|root,31B7M@2|Bacteria,1TZN5@1239|Firmicutes,4I8X9@91061|Bacilli,270NP@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
YYD2_k127_952187_1	452637.Oter_2474	1.024e-34	142.0	COG1752@1|root,COG1752@2|Bacteria,46UXK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
YYD2_k127_952679_9	518766.Rmar_2727	2.934e-14	81.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1072	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
YYD2_k127_952679_3	661478.OP10G_0347	5.597e-66	229.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD2_k127_952679_4	1463900.JOIX01000104_gene3059	2.029e-60	220.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
YYD2_k127_952679_5	661478.OP10G_1195	4.145e-59	211.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
YYD2_k127_952679_7	886293.Sinac_3111	1.838e-42	160.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
YYD2_k127_952679_1	592015.HMPREF1705_00545	1.942e-113	377.0	COG2605@1|root,COG2605@2|Bacteria,3TC8T@508458|Synergistetes	508458|Synergistetes	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD2_k127_952679_2	929556.Solca_0936	2.499e-92	331.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	2.4.1.21	ko:K00703,ko:K00754	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4,GT5	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD2_k127_952679_6	1380394.JADL01000004_gene5973	1.07e-56	208.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VF0J@28211|Alphaproteobacteria,2JYN6@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YYD2_k127_952679_0	234267.Acid_2705	1.513e-181	596.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD2_k127_956948_0	485915.Dret_1750	9.916e-197	632.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
YYD2_k127_956948_1	1121015.N789_10795	1.422e-76	269.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,1S297@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM pyridoxamine 5-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD2_k127_958468_2	1173028.ANKO01000208_gene5099	9.266e-78	269.0	COG1975@1|root,COG1975@2|Bacteria,1G2SP@1117|Cyanobacteria,1H9YC@1150|Oscillatoriales	1117|Cyanobacteria	O	'Xanthine and CO dehydrogenases maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
YYD2_k127_958468_4	1144275.COCOR_06640	4.088e-35	151.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,42SCH@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	MobA-like NTP transferase domain	mocA	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YYD2_k127_958468_3	1128421.JAGA01000002_gene1526	6.153e-41	159.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
YYD2_k127_958468_1	1379698.RBG1_1C00001G1004	1.367e-85	301.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
YYD2_k127_958468_0	1379698.RBG1_1C00001G1003	2.497e-118	403.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
YYD2_k127_958468_6	1379698.RBG1_1C00001G1002	4.689e-05	55.0	29494@1|root,2ZRPB@2|Bacteria	2|Bacteria	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
YYD2_k127_958468_5	555088.DealDRAFT_1022	1.761e-19	96.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,42K0F@68298|Syntrophomonadaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
YYD2_k127_960397_3	1519464.HY22_04635	1.2e-44	169.0	COG3186@1|root,COG3186@2|Bacteria	2|Bacteria	E	Phenylalanine-4-hydroxylase	phhA	GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
YYD2_k127_960397_0	880073.Calab_0341	1.271e-166	530.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YYD2_k127_960397_2	1047013.AQSP01000140_gene2469	2.329e-52	191.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YYD2_k127_960397_1	1254432.SCE1572_41875	1.492e-73	256.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria,2YTZF@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
YYD2_k127_982177_1	768704.Desmer_4043	1.798e-35	151.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YYD2_k127_982177_0	479434.Sthe_1107	1.843e-177	562.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi,27Z10@189775|Thermomicrobia	189775|Thermomicrobia	E	Urocanase C-terminal domain	-	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
YYD2_k127_98445_1	373903.Hore_06090	5.02e-31	128.0	COG1388@1|root,COG1450@1|root,COG4796@1|root,COG1388@2|Bacteria,COG1450@2|Bacteria,COG4796@2|Bacteria,1UK31@1239|Firmicutes,24PRP@186801|Clostridia,3WB70@53433|Halanaerobiales	186801|Clostridia	U	Type II and III secretion system protein	-	-	-	ko:K02453,ko:K02666	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	LysM,Secretin,Secretin_N
YYD2_k127_98445_0	1158318.ATXC01000001_gene807	3.117e-88	302.0	COG2805@1|root,COG2805@2|Bacteria,2G3S2@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD2_k127_98445_2	745718.JADT01000023_gene1431	3.111e-22	102.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,FG-GAP_2,LVIVD
YYD2_k127_990335_2	290397.Adeh_1023	1.876e-34	134.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2Z0TJ@29|Myxococcales	28221|Deltaproteobacteria	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
YYD2_k127_990335_1	1304885.AUEY01000001_gene3203	3.246e-58	218.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
YYD2_k127_990335_3	1499967.BAYZ01000050_gene2876	7.246e-29	128.0	COG0526@1|root,COG0526@2|Bacteria,2NQ68@2323|unclassified Bacteria	2|Bacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	resA_1	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
YYD2_k127_990335_4	643562.Daes_0505	1.177e-17	94.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria,2MD57@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	TIGRFAM redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YYD2_k127_990335_0	497321.C664_17300	9.295e-188	597.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VNTF@28216|Betaproteobacteria,2KVB8@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
## 2531 queries scanned
## Total time (seconds): 6.551179647445679
## Rate: 386.34 q/s