## Fri Feb 20 09:09:58 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/YYD3_bin.12.fa -m mmseqs --output YYD3_bin.12 --output_dir /data/result/bins/wyx/eggqs50+/YYD3_bin.12 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YYD3_k127_100005_0	1463920.JOGB01000015_gene1090	6.491e-75	270.0	COG3864@1|root,COG3864@2|Bacteria,2GWVA@201174|Actinobacteria	201174|Actinobacteria	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
YYD3_k127_100005_2	298655.KI912266_gene1935	4.314e-09	67.0	COG1216@1|root,COG4123@1|root,COG1216@2|Bacteria,COG4123@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
YYD3_k127_100005_1	627192.SLG_25140	1.053e-27	125.0	2EVK9@1|root,33P0C@2|Bacteria,1NDYB@1224|Proteobacteria,2UQHZ@28211|Alphaproteobacteria,2K9N4@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1010776_12	1121413.JMKT01000017_gene440	7.489e-06	54.0	2DHQR@1|root,300KJ@2|Bacteria,1Q6C0@1224|Proteobacteria,432U6@68525|delta/epsilon subdivisions,2WYED@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dehyd-heme_bind
YYD3_k127_1010776_3	344747.PM8797T_06150	1.49e-93	322.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1010776_7	1185876.BN8_05065	2.696e-22	109.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YYD3_k127_1010776_8	649349.Lbys_0105	1.559e-20	101.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
YYD3_k127_1010776_10	187272.Mlg_1073	5.325e-11	70.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,1RNSU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CK	Regulator of nitric oxide reductase transcription	nosR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind,Fer4,Fer4_5
YYD3_k127_1010776_6	311424.DhcVS_881	5.878e-27	123.0	COG0348@1|root,COG0348@2|Bacteria,2GB0I@200795|Chloroflexi,34DPT@301297|Dehalococcoidia	301297|Dehalococcoidia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YYD3_k127_1010776_5	1449049.JONW01000011_gene2133	1.553e-33	135.0	2E5IZ@1|root,330AA@2|Bacteria,1N9JX@1224|Proteobacteria,2UVCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1010776_2	1242864.D187_007066	2.351e-97	329.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria	1224|Proteobacteria	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_1010776_0	1267533.KB906733_gene3215	2.273e-223	722.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_1010776_1	502025.Hoch_4038	2.434e-100	337.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,MFS_1
YYD3_k127_1010776_9	682795.AciX8_2516	4.248e-11	67.0	COG2027@1|root,COG2027@2|Bacteria	2|Bacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	DUF3738,Peptidase_S13
YYD3_k127_1010776_11	861299.J421_1099	1.932e-10	73.0	COG2010@1|root,COG2010@2|Bacteria,1ZV02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_1010776_4	886293.Sinac_1153	1.916e-69	248.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_1031106_1	1279038.KB907345_gene3408	1.257e-27	114.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,2JR8S@204441|Rhodospirillales	204441|Rhodospirillales	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD3_k127_1031106_0	1122603.ATVI01000007_gene1691	1.811e-155	497.0	COG2813@1|root,COG2813@2|Bacteria,1QWWU@1224|Proteobacteria,1T5SK@1236|Gammaproteobacteria,1XARZ@135614|Xanthomonadales	1224|Proteobacteria	J	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
YYD3_k127_1031106_2	331869.BAL199_14202	1.439e-23	100.0	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,2U9CN@28211|Alphaproteobacteria,4BSC0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YYD3_k127_1035804_2	58344.JOEL01000022_gene988	2.057e-60	218.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
YYD3_k127_1035804_0	234267.Acid_5827	9.149e-238	760.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_1035804_1	234267.Acid_2032	4.725e-138	452.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_1035804_3	886293.Sinac_1155	5.022e-15	80.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
YYD3_k127_1148701_1	338963.Pcar_2234	4.194e-75	267.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,43TGR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YYD3_k127_1148701_0	1125863.JAFN01000001_gene241	2.187e-150	488.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
YYD3_k127_1148701_2	698757.Pogu_1036	1.326e-41	158.0	COG1225@1|root,arCOG00310@2157|Archaea,2XQPI@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD3_k127_1159289_1	314278.NB231_12219	5.437e-168	546.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1WX08@135613|Chromatiales	135613|Chromatiales	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
YYD3_k127_1159289_3	1442599.JAAN01000003_gene1096	2.768e-117	395.0	COG1360@1|root,COG3455@1|root,COG1360@2|Bacteria,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1T2Y7@1236|Gammaproteobacteria,1X5CU@135614|Xanthomonadales	135614|Xanthomonadales	N	Type IV VI secretion system protein, DotU family	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU,OmpA
YYD3_k127_1159289_2	1218084.BBJK01000017_gene1822	9.164e-147	477.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,2VKW8@28216|Betaproteobacteria,1K1D3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
YYD3_k127_1159289_9	247639.MGP2080_06247	2.423e-27	118.0	COG3521@1|root,COG3521@2|Bacteria,1N80I@1224|Proteobacteria,1SXD1@1236|Gammaproteobacteria,1J7AM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
YYD3_k127_1159289_5	190486.XAC4122	8.031e-73	263.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1T0B8@1236|Gammaproteobacteria,1X5CC@135614|Xanthomonadales	135614|Xanthomonadales	T	Forkhead associated domain	-	-	-	ko:K11894	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	FHA
YYD3_k127_1159289_6	349163.Acry_2098	1.023e-57	225.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
YYD3_k127_1159289_11	59538.XP_005979423.1	1.483e-06	52.0	COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla	33208|Metazoa	C	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
YYD3_k127_1159289_10	1267535.KB906767_gene3605	1.044e-12	76.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
YYD3_k127_1159289_4	264732.Moth_1322	1.785e-113	383.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,42F2X@68295|Thermoanaerobacterales	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YYD3_k127_1159289_8	204669.Acid345_1185	5.507e-29	125.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria,2JP27@204432|Acidobacteriia	204432|Acidobacteriia	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YYD3_k127_1159289_7	1499967.BAYZ01000068_gene1971	2.113e-56	209.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YYD3_k127_1159289_0	1382359.JIAL01000001_gene432	3.141e-172	566.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria,2JI1K@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YYD3_k127_1175077_2	234267.Acid_3693	1.915e-57	220.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y78P@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
YYD3_k127_1175077_3	379066.GAU_0069	1.051e-42	166.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_1175077_1	1455608.JDTH01000001_gene3463	4.269e-66	229.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,23V5W@183963|Halobacteria	183963|Halobacteria	O	COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YYD3_k127_1175077_0	575540.Isop_3152	6.549e-298	931.0	COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YYD3_k127_1188927_1	1125863.JAFN01000001_gene2041	1.208e-76	279.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YYD3_k127_1188927_5	485913.Krac_9241	9.475e-32	141.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_1188927_6	452637.Oter_4048	1.169e-12	72.0	2EE7S@1|root,3382A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1188927_0	857087.Metme_1588	2.59e-77	281.0	COG1520@1|root,COG1520@2|Bacteria,1NDU1@1224|Proteobacteria,1TH93@1236|Gammaproteobacteria,1XFEN@135618|Methylococcales	135618|Methylococcales	O	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1188927_4	401053.AciPR4_3363	1.476e-44	187.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1188927_3	1267535.KB906767_gene15	4.755e-59	222.0	COG0760@1|root,COG0760@2|Bacteria,3Y42Z@57723|Acidobacteria,2JHQ4@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
YYD3_k127_1188927_2	861299.J421_0975	6.744e-74	256.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yhhY	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	2.3.1.128,2.3.1.178	ko:K03790,ko:K03825,ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_4
YYD3_k127_1200250_0	861299.J421_0887	7.419e-117	393.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1ZUNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_1200250_1	749414.SBI_07512	9.195e-41	168.0	COG3447@1|root,COG3447@2|Bacteria,2GJB0@201174|Actinobacteria	201174|Actinobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MASE1,SpoIIE
YYD3_k127_1200250_2	909663.KI867150_gene2946	2.34e-20	105.0	COG2202@1|root,COG2206@1|root,COG2202@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions,2X706@28221|Deltaproteobacteria,2MQZA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_4,PAS_9,Response_reg,sCache_2
YYD3_k127_1204281_8	861299.J421_0393	6.072e-40	154.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0393|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1204281_2	1156935.QWE_23599	5.012e-102	344.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,4B9GW@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	malK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
YYD3_k127_1204281_4	484019.THA_846	2.198e-77	267.0	COG0395@1|root,COG0395@2|Bacteria,2GCIV@200918|Thermotogae	200918|Thermotogae	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
YYD3_k127_1204281_5	935948.KE386495_gene1086	9.782e-77	267.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,42FWJ@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
YYD3_k127_1204281_3	309803.CTN_0780	2.745e-84	294.0	COG1653@1|root,COG1653@2|Bacteria,2GC1I@200918|Thermotogae	200918|Thermotogae	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
YYD3_k127_1204281_9	398511.BpOF4_14105	3.861e-17	85.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,1ZGQV@1386|Bacillus	91061|Bacilli	K	GntR family transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
YYD3_k127_1204281_6	1210884.HG799463_gene10348	1.445e-66	238.0	COG2264@1|root,COG2264@2|Bacteria	2|Bacteria	J	protein methyltransferase activity	prmA1	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_31,PrmA
YYD3_k127_1204281_10	926549.KI421517_gene821	8.086e-13	75.0	COG0384@1|root,COG0384@2|Bacteria,4NMWV@976|Bacteroidetes,47PEQ@768503|Cytophagia	976|Bacteroidetes	S	phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
YYD3_k127_1204281_0	234267.Acid_3938	6.594e-181	599.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1204281_1	566466.NOR53_484	1.931e-103	350.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1J8R1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
YYD3_k127_1225080_1	1340493.JNIF01000004_gene667	1.11e-197	626.0	COG4262@1|root,COG4262@2|Bacteria,3Y3M2@57723|Acidobacteria	57723|Acidobacteria	S	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YYD3_k127_1225080_6	204669.Acid345_0110	1.498e-14	77.0	2EGTE@1|root,301RU@2|Bacteria,3Y93P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
YYD3_k127_1225080_7	379066.GAU_3059	3.846e-11	74.0	291F4@1|root,31505@2|Bacteria,1ZV76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1225080_2	522306.CAP2UW1_0240	5.129e-123	422.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2WGZK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
YYD3_k127_1225080_5	1340493.JNIF01000004_gene662	8.477e-32	128.0	COG1586@1|root,COG1586@2|Bacteria,3Y8GM@57723|Acidobacteria	57723|Acidobacteria	E	S-adenosylmethionine decarboxylase	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
YYD3_k127_1225080_0	234267.Acid_4800	0.0	1131.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
YYD3_k127_1225080_4	1185876.BN8_00131	7.237e-55	197.0	COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,47Q3P@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
YYD3_k127_1225080_3	861299.J421_4117	1.079e-61	216.0	COG2318@1|root,COG2318@2|Bacteria,1ZV1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_1225080_8	1121035.AUCH01000005_gene219	3.803e-09	64.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
YYD3_k127_1232509_0	204669.Acid345_2476	5.12e-27	128.0	COG0729@1|root,COG4775@1|root,COG0729@2|Bacteria,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
YYD3_k127_1232509_1	1340493.JNIF01000003_gene3549	8.962e-07	61.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_1242183_2	1122915.AUGY01000060_gene151	5.754e-22	109.0	COG0671@1|root,COG0671@2|Bacteria,1VBSU@1239|Firmicutes,4HPN8@91061|Bacilli,26S0G@186822|Paenibacillaceae	91061|Bacilli	I	Phosphoesterase PA-phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YYD3_k127_1242183_3	1463821.JOGR01000006_gene2680	0.0001261	51.0	COG0346@1|root,COG0346@2|Bacteria,2IM1B@201174|Actinobacteria,4F0BE@85014|Glycomycetales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1242183_1	234267.Acid_3123	3.083e-25	115.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_1242183_0	1267535.KB906767_gene1287	2.746e-152	501.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_1268432_2	1267535.KB906767_gene3869	3.304e-94	325.0	COG3637@1|root,COG3637@2|Bacteria,3Y783@57723|Acidobacteria	57723|Acidobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
YYD3_k127_1268432_0	1396418.BATQ01000051_gene63	3.229e-178	567.0	COG0715@1|root,COG0715@2|Bacteria,46U3D@74201|Verrucomicrobia,2IU5R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
YYD3_k127_1268432_1	530564.Psta_4090	8.541e-98	345.0	COG0600@1|root,COG0600@2|Bacteria,2IYBH@203682|Planctomycetes	203682|Planctomycetes	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
YYD3_k127_1268432_4	530564.Psta_4089	3.929e-70	247.0	COG1116@1|root,COG1116@2|Bacteria,2IYQ7@203682|Planctomycetes	203682|Planctomycetes	P	COG1116 ABC-type nitrate sulfonate	-	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
YYD3_k127_1268432_3	1396141.BATP01000062_gene4436	8.741e-83	289.0	COG1116@1|root,COG1116@2|Bacteria,46UJC@74201|Verrucomicrobia,2ITHC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YYD3_k127_1268432_5	671143.DAMO_1432	1.579e-61	220.0	COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria	2|Bacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_1268432_6	1128421.JAGA01000003_gene3320	4.887e-26	110.0	COG1051@1|root,COG1051@2|Bacteria,2NQ2W@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	mutT	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_1268604_3	163908.KB235896_gene4415	4.771e-36	148.0	COG1442@1|root,COG1442@2|Bacteria	2|Bacteria	M	lipopolysaccharide 3-alpha-galactosyltransferase activity	kdsB2	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
YYD3_k127_1268604_7	1184609.KILIM_087_00090	0.0003993	52.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YYD3_k127_1268604_4	29306.JOBE01000063_gene5501	1.78e-20	104.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_1268604_5	1266909.AUAG01000011_gene996	9.336e-11	72.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1WX56@135613|Chromatiales	135613|Chromatiales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
YYD3_k127_1268604_0	163908.KB235896_gene3037	8.829e-78	283.0	COG0438@1|root,COG0438@2|Bacteria,1G09P@1117|Cyanobacteria,1HRH4@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD3_k127_1268604_1	572479.Hprae_0340	1.424e-66	250.0	COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,25ERN@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.348	ko:K06338,ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_1268604_2	795359.TOPB45_0361	1.606e-53	211.0	COG2148@1|root,COG2148@2|Bacteria,2GHZH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
YYD3_k127_1268604_6	410358.Mlab_1392	2.329e-09	60.0	COG0644@1|root,arCOG00570@2157|Archaea,2XUI9@28890|Euryarchaeota,2N9DD@224756|Methanomicrobia	224756|Methanomicrobia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,HI0933_like,Lycopene_cycl
YYD3_k127_1299999_2	204669.Acid345_2578	6.89e-09	61.0	COG0412@1|root,COG0515@1|root,COG1262@1|root,COG0412@2|Bacteria,COG0515@2|Bacteria,COG1262@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_1299999_3	1380393.JHVP01000006_gene3978	7.536e-08	64.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Lactonase,TIG
YYD3_k127_1299999_1	234267.Acid_5219	2.687e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,3Y7YB@57723|Acidobacteria	2|Bacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
YYD3_k127_1299999_0	234267.Acid_5749	8.558e-79	274.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_134148_0	1305737.JAFX01000001_gene612	1.285e-101	349.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_134148_1	661478.OP10G_1598	2.459e-34	135.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_134148_2	926550.CLDAP_09190	3.321e-34	139.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_1357398_3	234267.Acid_4161	1.004e-43	168.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
YYD3_k127_1357398_5	1121406.JAEX01000002_gene912	1.102e-18	93.0	COG1989@1|root,COG1989@2|Bacteria,1R34X@1224|Proteobacteria,42V6M@68525|delta/epsilon subdivisions,2WRP6@28221|Deltaproteobacteria,2MCVZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	NOU	PFAM Peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
YYD3_k127_1357398_9	991905.SL003B_3666	2.92e-05	51.0	COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,2UJE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Flp Fap pilin component	MA20_03885	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
YYD3_k127_1357398_7	370438.PTH_1447	2.131e-08	62.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,262QH@186807|Peptococcaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
YYD3_k127_1357398_4	1121459.AQXE01000002_gene1225	1.831e-37	156.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YYD3_k127_1357398_1	648996.Theam_0530	2.968e-52	203.0	COG1893@1|root,COG1893@2|Bacteria,2G45N@200783|Aquificae	200783|Aquificae	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
YYD3_k127_1357398_10	1158050.KB895452_gene698	0.0007861	52.0	COG1807@1|root,COG1807@2|Bacteria,2ICG0@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD3_k127_1357398_6	1380391.JIAS01000015_gene296	7.692e-11	76.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,2JU6X@204441|Rhodospirillales	204441|Rhodospirillales	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
YYD3_k127_1357398_0	1304872.JAGC01000003_gene2874	2.195e-139	455.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42ZMZ@68525|delta/epsilon subdivisions,2X27A@28221|Deltaproteobacteria,2M8TC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_1357398_2	1403819.BATR01000092_gene2705	1.169e-50	191.0	COG0500@1|root,COG2226@2|Bacteria,46XQZ@74201|Verrucomicrobia,2IWE6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_1357398_8	1382306.JNIM01000001_gene3762	2.221e-07	64.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD3_k127_14092_2	1210884.HG799464_gene10528	6.441e-155	494.0	COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes	203682|Planctomycetes	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
YYD3_k127_14092_5	1242864.D187_009687	1.027e-97	327.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria,2YWGV@29|Myxococcales	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
YYD3_k127_14092_1	221288.JH992901_gene3895	2.948e-162	525.0	COG0715@1|root,COG0715@2|Bacteria,1GFIM@1117|Cyanobacteria	1117|Cyanobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
YYD3_k127_14092_4	1210884.HG799464_gene10580	6.279e-134	439.0	COG0475@1|root,COG0475@2|Bacteria,2IY97@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YYD3_k127_14092_0	379066.GAU_0803	1.297e-213	706.0	COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_14092_3	243090.RB4667	1.734e-137	452.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_14092_6	948106.AWZT01000001_gene5337	6.14e-56	205.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,1K3AS@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
YYD3_k127_14092_7	1123008.KB905694_gene1564	5.656e-45	166.0	COG4430@1|root,COG4430@2|Bacteria,4NQAJ@976|Bacteroidetes	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
YYD3_k127_1428002_4	1280952.HJA_08844	8.418e-06	55.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF4440,SnoaL_2,SnoaL_3,YkuD
YYD3_k127_1428002_3	156889.Mmc1_0348	1.092e-40	159.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TQTD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
YYD3_k127_1428002_2	240015.ACP_3525	6.611e-47	182.0	COG3182@1|root,COG3182@2|Bacteria,3Y2R7@57723|Acidobacteria,2JIBB@204432|Acidobacteriia	204432|Acidobacteriia	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
YYD3_k127_1428002_0	279238.Saro_1864	7.882e-102	349.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2TTWF@28211|Alphaproteobacteria,2K2II@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_1428002_1	452637.Oter_0578	1.478e-87	299.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1442807_1	1168034.FH5T_18125	1.247e-12	70.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_1442807_0	234267.Acid_6847	6.99e-60	225.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_144588_1	1380394.JADL01000011_gene4021	3.028e-84	289.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2TRBF@28211|Alphaproteobacteria,2JYWK@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K05819,ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12,2.A.1.15	-	-	MFS_1,Sugar_tr
YYD3_k127_144588_3	1114922.CIFAM_06_00050	2.244e-56	212.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
YYD3_k127_144588_4	1121920.AUAU01000011_gene222	3.971e-54	192.0	COG3189@1|root,COG3189@2|Bacteria,3Y86R@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
YYD3_k127_144588_6	1121346.KB899827_gene482	2.14e-05	55.0	COG5492@1|root,COG5492@2|Bacteria,1UFP5@1239|Firmicutes,4HFJH@91061|Bacilli,26RD3@186822|Paenibacillaceae	91061|Bacilli	N	Bacterial Ig-like domain 2	tNN	-	-	-	-	-	-	-	-	-	-	-	Big_2
YYD3_k127_144588_0	909613.UO65_3523	3.619e-141	454.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DXA1@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YYD3_k127_144588_5	420324.KI911992_gene7698	2.502e-09	69.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_144588_2	97096.XP_007790920.1	1.59e-62	231.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_1448460_0	1209072.ALBT01000023_gene4126	7.469e-179	581.0	COG0627@1|root,COG0627@2|Bacteria,1MX6W@1224|Proteobacteria,1T3M9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_1448460_2	287986.DV20_04860	4.915e-54	196.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4E45T@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_1448460_6	682795.AciX8_1793	1.155e-05	48.0	COG2027@1|root,COG2027@2|Bacteria,3Y64Y@57723|Acidobacteria,2JKU1@204432|Acidobacteriia	204432|Acidobacteriia	M	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
YYD3_k127_1448460_5	268739.Nmlp_1774	3.557e-10	68.0	arCOG02709@1|root,arCOG02709@2157|Archaea,2XXZ2@28890|Euryarchaeota,23W35@183963|Halobacteria	183963|Halobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	glo2	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_1448460_1	926550.CLDAP_21950	5.605e-173	558.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
YYD3_k127_1448460_4	665956.HMPREF1032_03657	1.811e-18	97.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,3WHPI@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_1448460_3	247633.GP2143_17796	4.676e-37	153.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1448460_7	639030.JHVA01000001_gene2808	6.371e-05	46.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria,2JM9F@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1452903_3	1122604.JONR01000059_gene1132	2.233e-10	61.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,1SZ73@1236|Gammaproteobacteria,1X33T@135614|Xanthomonadales	135614|Xanthomonadales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_1452903_4	493475.GARC_5346	1.051e-07	61.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_1452903_1	452637.Oter_1642	6.385e-158	507.0	COG0563@1|root,COG0563@2|Bacteria,46UF6@74201|Verrucomicrobia,3K7G4@414999|Opitutae	414999|Opitutae	F	adenylate kinase	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
YYD3_k127_1452903_0	1499967.BAYZ01000036_gene2415	1.055e-166	537.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YYD3_k127_1452903_2	1335760.ASTG01000003_gene1750	1.937e-23	112.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1452903_5	1165096.ARWF01000001_gene441	3.771e-05	48.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1474400_0	452662.SJA_C2-03510	3.63e-135	438.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
YYD3_k127_1474400_2	1245469.S58_53610	4.676e-47	185.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,3JW83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_1483390_2	861299.J421_2216	1.051e-26	111.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_1483390_1	1380390.JIAT01000009_gene1773	1.762e-52	204.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_1483390_0	570967.JMLV01000008_gene1306	6.306e-93	322.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2JPVS@204441|Rhodospirillales	204441|Rhodospirillales	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
YYD3_k127_1483390_5	1128421.JAGA01000002_gene374	0.0003777	51.0	COG4632@1|root,COG4632@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NAGPA
YYD3_k127_1483390_3	861299.J421_4310	2.203e-07	57.0	2EA12@1|root,3346D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
YYD3_k127_1483390_4	378806.STAUR_3497	0.0001479	46.0	28KD9@1|root,2Z9ZW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1484581_0	215803.DB30_0399	1.117e-126	412.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
YYD3_k127_1484581_1	868864.Dester_1458	2.363e-102	352.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YYD3_k127_1484581_2	290397.Adeh_3471	5.67e-51	185.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_1484868_2	1379698.RBG1_1C00001G1800	1.032e-06	53.0	arCOG11509@1|root,31KIR@2|Bacteria,2NR0T@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1484868_1	1210884.HG799463_gene9717	1.76e-99	334.0	COG1262@1|root,COG1262@2|Bacteria,2IZNJ@203682|Planctomycetes	203682|Planctomycetes	CO	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YYD3_k127_1484868_0	234267.Acid_3938	3.776e-185	612.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1492452_0	234267.Acid_7510	1.708e-103	356.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1507465_19	1340493.JNIF01000004_gene304	1.977e-23	109.0	COG1404@1|root,COG5164@1|root,COG1404@2|Bacteria,COG5164@2|Bacteria,3Y5WB@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
YYD3_k127_1507465_10	1198114.AciX9_2892	1.301e-88	316.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD3_k127_1507465_15	518766.Rmar_2028	8.828e-80	297.0	COG0457@1|root,COG3829@1|root,COG0457@2|Bacteria,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1FIME@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
YYD3_k127_1507465_11	383372.Rcas_2891	3.186e-84	291.0	COG3804@1|root,COG3804@2|Bacteria,2G7MJ@200795|Chloroflexi	200795|Chloroflexi	C	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
YYD3_k127_1507465_4	1089547.KB913013_gene2262	2.976e-145	485.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
YYD3_k127_1507465_24	1313421.JHBV01000041_gene3549	3.999e-09	68.0	2C08E@1|root,2ZBCG@2|Bacteria,4NGBR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1507465_16	298655.KI912266_gene1355	2.781e-39	166.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ETCD@85013|Frankiales	201174|Actinobacteria	S	Laminin G domain	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
YYD3_k127_1507465_21	290317.Cpha266_0859	2.184e-13	83.0	COG0823@1|root,COG0823@2|Bacteria,1FEIQ@1090|Chlorobi	1090|Chlorobi	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
YYD3_k127_1507465_5	266117.Rxyl_2946	5.779e-135	466.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
YYD3_k127_1507465_28	401053.AciPR4_4100	0.0008175	45.0	COG2027@1|root,COG2027@2|Bacteria,3Y64Y@57723|Acidobacteria,2JKU1@204432|Acidobacteriia	204432|Acidobacteriia	M	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
YYD3_k127_1507465_27	1267534.KB906758_gene2527	3.744e-05	48.0	COG2027@1|root,COG2027@2|Bacteria,3Y7ZS@57723|Acidobacteria,2JMZE@204432|Acidobacteriia	204432|Acidobacteriia	M	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
YYD3_k127_1507465_25	1246995.AFR_22940	2.958e-07	60.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD3_k127_1507465_26	234267.Acid_1154	4.544e-07	55.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1507465_17	1209072.ALBT01000032_gene2092	2.037e-34	138.0	2CK8Q@1|root,31PVK@2|Bacteria,1RIRH@1224|Proteobacteria,1SD2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1507465_1	518766.Rmar_0629	1.068e-221	724.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
YYD3_k127_1507465_18	234267.Acid_4928	8.468e-27	117.0	29ZWG@1|root,30MXU@2|Bacteria,3Y5VK@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_1507465_9	234267.Acid_3938	2.084e-94	340.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1507465_2	861299.J421_0790	2.121e-164	557.0	COG0405@1|root,COG0823@1|root,COG0405@2|Bacteria,COG0823@2|Bacteria,1ZSSP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
YYD3_k127_1507465_0	330214.NIDE2536	3.335e-247	778.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YYD3_k127_1507465_22	204669.Acid345_3199	7.052e-11	70.0	2ED8Q@1|root,33759@2|Bacteria,3Y5NT@57723|Acidobacteria,2JJWR@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
YYD3_k127_1507465_6	1519464.HY22_10895	2.039e-132	432.0	COG0473@1|root,COG0473@2|Bacteria,1FEMW@1090|Chlorobi	1090|Chlorobi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD3_k127_1507465_20	1415780.JPOG01000001_gene3194	2.262e-21	108.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YYD3_k127_1507465_12	525904.Tter_0599	8.382e-84	291.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
YYD3_k127_1507465_8	926560.KE387023_gene2040	2.354e-103	350.0	COG0624@1|root,COG0624@2|Bacteria,1WMBR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_1507465_7	1469245.JFBG01000027_gene1490	1.434e-108	380.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
YYD3_k127_1507465_14	471852.Tcur_4423	7.797e-80	278.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4EIZR@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_1507465_13	383372.Rcas_4417	1.229e-82	285.0	COG2358@1|root,COG2358@2|Bacteria,2G9YX@200795|Chloroflexi,377E1@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
YYD3_k127_1507465_3	2002.JOEQ01000005_gene3463	1.055e-160	528.0	COG4666@1|root,COG4666@2|Bacteria,2H91Y@201174|Actinobacteria,4EM5T@85012|Streptosporangiales	201174|Actinobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YYD3_k127_1507465_23	1382359.JIAL01000001_gene1053	1.235e-09	61.0	2C987@1|root,331JK@2|Bacteria,3Y5R0@57723|Acidobacteria,2JK28@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1508372_4	1121377.KB906402_gene3334	3.642e-24	115.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,Guanylate_cyc,NB-ARC,TPR_12
YYD3_k127_1508372_3	388413.ALPR1_00690	4.458e-28	116.0	2CFT1@1|root,32S2F@2|Bacteria,4NTM5@976|Bacteroidetes,47RXR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1508372_5	219305.MCAG_00121	1.259e-14	78.0	2CRSQ@1|root,32SPK@2|Bacteria,2IQ50@201174|Actinobacteria,4DESH@85008|Micromonosporales	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
YYD3_k127_1508372_2	247490.KSU1_D0599	1.777e-31	141.0	COG4191@1|root,COG4191@2|Bacteria,2IYZD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD3_k127_1508372_1	204669.Acid345_2946	3.925e-38	159.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,3Y56X@57723|Acidobacteria,2JM0P@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
YYD3_k127_1508372_0	861299.J421_6076	2.848e-81	283.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
YYD3_k127_1509996_2	877421.AUJT01000019_gene2788	1.302e-24	111.0	COG0562@1|root,COG0562@2|Bacteria,1UDAR@1239|Firmicutes,25HZF@186801|Clostridia,27RAQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	UDP-galactopyranose mutase	-	-	-	-	-	-	-	-	-	-	-	-	GLF,NAD_binding_8
YYD3_k127_1509996_0	614083.AWQR01000023_gene159	1.586e-116	383.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2VU66@28216|Betaproteobacteria,4AG0U@80864|Comamonadaceae	28216|Betaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD3_k127_1509996_1	290315.Clim_1892	7.621e-40	152.0	COG0279@1|root,COG0279@2|Bacteria	2|Bacteria	G	D-glycero-D-manno-heptose 7-phosphate metabolic process	gmhA	-	3.1.3.82,3.1.3.83,5.3.1.28	ko:K03271,ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05645,R05647,R09768,R09769,R09771	RC00017,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YYD3_k127_1511659_0	1038860.AXAP01000018_gene3108	7.329e-144	477.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_1511659_5	1123024.AUII01000001_gene2941	1.99e-42	159.0	COG0251@1|root,COG0251@2|Bacteria,2IIXG@201174|Actinobacteria,4EAYK@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
YYD3_k127_1511659_6	391603.FBALC1_15127	2.963e-33	140.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1511659_1	1267535.KB906767_gene5132	1.211e-117	411.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_1511659_2	439235.Dalk_3479	3.01e-76	273.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2WKBM@28221|Deltaproteobacteria,2MHN3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
YYD3_k127_1511659_3	1234364.AMSF01000015_gene3198	4.395e-65	229.0	COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1T0AZ@1236|Gammaproteobacteria,1XCZV@135614|Xanthomonadales	135614|Xanthomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
YYD3_k127_1511659_4	1123508.JH636439_gene1117	2.124e-43	171.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_1532299_0	1082933.MEA186_09775	7.748e-75	265.0	COG2041@1|root,COG2041@2|Bacteria,1NR5V@1224|Proteobacteria,2UQ6F@28211|Alphaproteobacteria,43R8Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
YYD3_k127_1532299_3	243164.DET1294	3.749e-05	51.0	COG2204@1|root,COG3311@1|root,COG2204@2|Bacteria,COG3311@2|Bacteria,2G9P5@200795|Chloroflexi,34CV5@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
YYD3_k127_1532299_1	1123256.KB907943_gene444	1.253e-65	232.0	COG0412@1|root,COG0412@2|Bacteria,1R8KY@1224|Proteobacteria,1T08Q@1236|Gammaproteobacteria,1XCZA@135614|Xanthomonadales	135614|Xanthomonadales	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YYD3_k127_1532299_2	234267.Acid_2176	2.268e-21	100.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_1542502_7	556268.OFAG_01559	4.216e-12	68.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,47297@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	DNA topoisomerase	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
YYD3_k127_1542502_4	379066.GAU_1959	4.964e-46	176.0	2EQJ9@1|root,33I5A@2|Bacteria,1ZTSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1542502_6	861299.J421_1376	6.676e-33	143.0	2AER0@1|root,314MK@2|Bacteria,1ZTTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1542502_2	118173.KB235914_gene835	3.971e-83	301.0	COG2133@1|root,COG2133@2|Bacteria,1G2QD@1117|Cyanobacteria,1H7CA@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
YYD3_k127_1542502_1	204669.Acid345_4403	3.424e-124	406.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5
YYD3_k127_1542502_8	411467.BACCAP_00375	9.967e-09	67.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,2488X@186801|Clostridia,26825@186813|unclassified Clostridiales	186801|Clostridia	K	ParB-like nuclease domain	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD3_k127_1542502_9	338963.Pcar_0504	8.707e-08	60.0	2BP69@1|root,32HXD@2|Bacteria,1Q1KM@1224|Proteobacteria,437BM@68525|delta/epsilon subdivisions,2X2GS@28221|Deltaproteobacteria,43VCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1542502_0	861299.J421_3743	1.215e-145	470.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_1542502_3	452637.Oter_0829	7.484e-56	204.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_1542502_5	264198.Reut_B5452	2.822e-39	164.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria,1N0Y7@1224|Proteobacteria,2VP6G@28216|Betaproteobacteria,1K67U@119060|Burkholderiaceae	28216|Betaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,MASE1
YYD3_k127_1549195_2	880072.Desac_1962	3.877e-36	158.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CF9@68525|delta/epsilon subdivisions,2X7QB@28221|Deltaproteobacteria,2MS55@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16087,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.2,1.B.14.3	-	-	Plug,TonB_dep_Rec
YYD3_k127_1549195_3	1123255.JHYS01000007_gene1643	5.882e-32	146.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria,4AF43@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM multicopper oxidase type	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
YYD3_k127_1549195_4	204669.Acid345_1170	5.202e-29	124.0	COG1917@1|root,COG1917@2|Bacteria,3Y802@57723|Acidobacteria,2JN05@204432|Acidobacteriia	204432|Acidobacteriia	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1549195_1	1267533.KB906734_gene3978	9.018e-100	329.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_1549195_0	1415779.JOMH01000001_gene3235	4.35e-163	520.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,1RZ6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Pfam Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_1551893_1	1476583.DEIPH_ctg012orf0054	1.898e-82	278.0	COG0708@1|root,COG0708@2|Bacteria,1WMBY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YYD3_k127_1551893_0	1179773.BN6_53990	2.195e-167	539.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4E013@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
YYD3_k127_1552085_3	1267535.KB906767_gene3667	7.698e-50	182.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_1552085_4	234267.Acid_6900	1.677e-49	187.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
YYD3_k127_1552085_1	1267535.KB906767_gene3668	1.622e-112	386.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738,Peptidase_M56
YYD3_k127_1552085_2	234267.Acid_6900	5.67e-57	211.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
YYD3_k127_1552085_0	1267535.KB906767_gene3671	1.37e-201	651.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria,2JKK3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1552085_5	682795.AciX8_2512	3.405e-41	154.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria,2JKK3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1554845_1	1049564.TevJSym_aw00650	4.073e-67	245.0	COG3673@1|root,COG3673@2|Bacteria	2|Bacteria	M	conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,DUF4280
YYD3_k127_1554845_3	1394178.AWOO02000001_gene1228	2.507e-25	110.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4EQIN@85012|Streptosporangiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_1554845_2	459495.SPLC1_S171240	7.63e-47	183.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
YYD3_k127_1554845_4	1217718.ALOU01000034_gene2889	0.0001163	49.0	2F8W1@1|root,3417Y@2|Bacteria,1NXB4@1224|Proteobacteria,2W35T@28216|Betaproteobacteria,1K8UE@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1554845_0	234267.Acid_2620	1.326e-194	616.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1560100_2	1229909.NSED_07250	4.045e-08	55.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S7I@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18594	ko00720,ko01120,map00720,map01120	-	R03157	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YYD3_k127_1560100_0	1121472.AQWN01000001_gene188	2.538e-88	310.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YYD3_k127_1560100_1	234267.Acid_1009	2.968e-84	291.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria	57723|Acidobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YYD3_k127_1561748_6	926560.KE387027_gene263	1.264e-66	233.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YYD3_k127_1561748_1	869210.Marky_1927	1.042e-180	583.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD3_k127_1561748_3	1380394.JADL01000018_gene1921	1.932e-162	515.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria,2JYNK@204441|Rhodospirillales	204441|Rhodospirillales	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
YYD3_k127_1561748_4	1380394.JADL01000018_gene1922	3.829e-152	486.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1561748_2	398525.KB900701_gene7345	3.698e-164	521.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2TWC9@28211|Alphaproteobacteria,3JVP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YYD3_k127_1561748_9	269799.Gmet_2627	4.452e-25	122.0	COG1073@1|root,COG1073@2|Bacteria,1R9V1@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF900
YYD3_k127_1561748_10	1306406.ASHX01000002_gene4666	1.909e-14	83.0	COG4106@1|root,COG4106@2|Bacteria,2GK0K@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_1561748_0	1267535.KB906767_gene903	3.937e-211	677.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA2	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
YYD3_k127_1561748_7	56780.SYN_01954	2.809e-48	193.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
YYD3_k127_1561748_5	1163407.UU7_04432	5.95e-78	282.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X5U0@135614|Xanthomonadales	135614|Xanthomonadales	T	c-di-gmp phosphodiesterase	pdeA	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,PAS_9
YYD3_k127_1561748_11	1002339.HMPREF9373_2632	2.101e-08	59.0	2E27W@1|root,30SFJ@2|Bacteria,1NI6N@1224|Proteobacteria,1SRI1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1561748_8	195250.CM001776_gene1121	1.497e-40	164.0	COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria,1H175@1129|Synechococcus	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1566013_3	1040989.AWZU01000019_gene1861	5.39e-92	309.0	COG0730@1|root,COG0730@2|Bacteria,1PK9F@1224|Proteobacteria,2TRK3@28211|Alphaproteobacteria,3JVTD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
YYD3_k127_1566013_2	555079.Toce_0450	6.907e-101	342.0	COG0477@1|root,COG2814@2|Bacteria,1UHNA@1239|Firmicutes,25F3B@186801|Clostridia,42J72@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
YYD3_k127_1566013_0	234267.Acid_4063	2.381e-118	396.0	COG2421@1|root,COG2421@2|Bacteria,3Y7AP@57723|Acidobacteria	57723|Acidobacteria	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
YYD3_k127_1566013_5	926549.KI421517_gene3367	2.025e-80	284.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YYD3_k127_1566013_16	1233950.IW22_19275	1.045e-11	73.0	28NR7@1|root,2ZBQI@2|Bacteria,4NMCH@976|Bacteroidetes,1I5M4@117743|Flavobacteriia,3ZT6F@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1566013_8	1276756.AUEX01000004_gene2547	1.729e-42	171.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,4AA1T@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
YYD3_k127_1566013_11	247633.GP2143_18121	1.025e-24	113.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1566013_6	379066.GAU_3463	8.779e-59	209.0	2DMXW@1|root,32UAS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1566013_7	1163407.UU7_07408	1.747e-44	165.0	COG0346@1|root,COG0346@2|Bacteria,1RE6F@1224|Proteobacteria,1SP6R@1236|Gammaproteobacteria,1X75F@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_1566013_1	251229.Chro_2223	1.125e-102	342.0	COG0500@1|root,COG2226@2|Bacteria,1G5RE@1117|Cyanobacteria	1117|Cyanobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1566013_9	218284.CCDN010000001_gene1942	9.384e-37	145.0	COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,4HHSJ@91061|Bacilli,1ZFRA@1386|Bacillus	91061|Bacilli	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YYD3_k127_1566013_15	1423144.Gal_00228	2.533e-18	93.0	COG0500@1|root,COG0500@2|Bacteria,1R5D7@1224|Proteobacteria,2UA9F@28211|Alphaproteobacteria,34FUX@302485|Phaeobacter	28211|Alphaproteobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
YYD3_k127_1566013_12	936136.ARRT01000006_gene2334	4.285e-22	102.0	COG0454@1|root,COG0456@2|Bacteria,1NF6A@1224|Proteobacteria,2UHY0@28211|Alphaproteobacteria,4BJQR@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
YYD3_k127_1566013_13	743525.TSC_c02450	6.189e-20	99.0	COG0500@1|root,COG2226@2|Bacteria,1WJAK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_1566013_10	1122182.KB903813_gene2605	2.103e-27	121.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4DENZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_1566013_4	861299.J421_1365	8.147e-89	314.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_1568772_1	483219.LILAB_27660	1.151e-60	210.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,42Z2R@68525|delta/epsilon subdivisions,2WUGF@28221|Deltaproteobacteria,2Z37Y@29|Myxococcales	28221|Deltaproteobacteria	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Mac
YYD3_k127_1568772_3	1384056.N787_11275	2.902e-11	73.0	COG1506@1|root,COG1506@2|Bacteria,1QWCQ@1224|Proteobacteria,1S38C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6
YYD3_k127_1568772_0	1340493.JNIF01000003_gene1629	7.167e-123	419.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1568772_2	234267.Acid_5676	5.092e-28	116.0	COG0515@1|root,COG1262@1|root,COG1506@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	1.14.99.50,2.7.11.1	ko:K01990,ko:K08884,ko:K12132,ko:K18912	ko00340,map00340	M00254	R11013	RC03323,RC03324	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000	3.A.1	-	-	FGE-sulfatase,Peptidase_S15,Pkinase
YYD3_k127_1571829_1	946235.CAER01000008_gene395	4.965e-76	273.0	COG4993@1|root,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli	91061|Bacilli	CG	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_1571829_3	404589.Anae109_0806	9.213e-24	109.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2Z1J6@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_1571829_2	518766.Rmar_1007	2.314e-27	123.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FJR9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_1571829_0	1463887.KL590022_gene2781	3.148e-192	628.0	COG0429@1|root,COG3345@1|root,COG0429@2|Bacteria,COG3345@2|Bacteria,2GKJ5@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,NPCBM,NPCBM_assoc
YYD3_k127_1571829_8	543632.JOJL01000014_gene9196	0.0006341	44.0	COG2220@1|root,COG2220@2|Bacteria,2HEV7@201174|Actinobacteria,4DHRX@85008|Micromonosporales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
YYD3_k127_1571829_6	41431.PCC8801_0908	1.525e-05	53.0	COG0500@1|root,COG2226@2|Bacteria,1GQ5G@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_1571829_7	1038859.AXAU01000001_gene3253	0.0001439	52.0	COG0500@1|root,COG2226@2|Bacteria,1MZ58@1224|Proteobacteria,2UETX@28211|Alphaproteobacteria,3K4ZH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_1571829_4	443144.GM21_3334	1.653e-16	81.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YYD3_k127_1574302_5	1437425.CSEC_1554	3.513e-38	152.0	COG0500@1|root,COG0500@2|Bacteria,2JH3P@204428|Chlamydiae	204428|Chlamydiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1574302_4	401053.AciPR4_3363	1.756e-56	226.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1574302_1	1123242.JH636435_gene2360	4.004e-134	448.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_1574302_6	335543.Sfum_0737	8.72e-33	132.0	COG0589@1|root,COG0589@2|Bacteria,1NDJW@1224|Proteobacteria,430KQ@68525|delta/epsilon subdivisions,2WVKY@28221|Deltaproteobacteria,2MRZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_1574302_0	497321.C664_15668	5.784e-202	643.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	ligB	-	1.13.11.57	ko:K04099	ko00627,ko01120,map00627,map01120	-	R03550,R04280,R09565	RC00233,RC00535,RC02567,RC02694	ko00000,ko00001,ko01000	-	-	-	LigA,LigB
YYD3_k127_1574302_7	1088721.NSU_2813	0.0004875	51.0	2FIXR@1|root,34ANN@2|Bacteria,1NNY2@1224|Proteobacteria,2UMAG@28211|Alphaproteobacteria,2K886@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
YYD3_k127_1574302_3	1340493.JNIF01000003_gene3476	1.527e-83	297.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
YYD3_k127_1574302_2	234267.Acid_2032	1.025e-115	388.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_1580385_3	439375.Oant_2734	1.614e-53	203.0	COG0500@1|root,COG0500@2|Bacteria,1RJ4T@1224|Proteobacteria,2UCY0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_1580385_2	156889.Mmc1_0107	2.254e-84	293.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glycos_transf_2,NTP_transf_5
YYD3_k127_1580385_0	316058.RPB_1530	3.752e-123	407.0	28KU8@1|root,2ZCM9@2|Bacteria,1NKE5@1224|Proteobacteria,2UMUZ@28211|Alphaproteobacteria,3K5CQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	STELLO glycosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	STELLO
YYD3_k127_1580385_1	864702.OsccyDRAFT_2354	1.118e-112	391.0	28IB2@1|root,2Z8DJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1589169_3	479434.Sthe_0453	1.064e-77	278.0	COG1409@1|root,COG1409@2|Bacteria,2G88X@200795|Chloroflexi,27Z25@189775|Thermomicrobia	189775|Thermomicrobia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_1589169_12	1278073.MYSTI_05277	3.412e-14	85.0	COG3746@1|root,COG3746@2|Bacteria,1N2GT@1224|Proteobacteria,42W61@68525|delta/epsilon subdivisions,2WRSI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
YYD3_k127_1589169_6	234267.Acid_4036	2.81e-56	219.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
YYD3_k127_1589169_9	1340493.JNIF01000003_gene2123	2.901e-26	124.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1589169_2	1210884.HG799463_gene9741	1.818e-132	449.0	COG3852@1|root,COG3852@2|Bacteria,2J4Y6@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YYD3_k127_1589169_8	1047013.AQSP01000139_gene2414	1.513e-33	140.0	COG0457@1|root,COG0457@2|Bacteria,2NRWN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1589169_7	1209072.ALBT01000032_gene2094	4.606e-52	188.0	COG1917@1|root,COG1917@2|Bacteria,1QEE2@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,DUF4437
YYD3_k127_1589169_10	204669.Acid345_3218	1.33e-25	125.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria,2JKBG@204432|Acidobacteriia	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_1589169_5	1179773.BN6_32750	4.72e-65	228.0	2C1XE@1|root,301BZ@2|Bacteria,2IGAE@201174|Actinobacteria,4E3XG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1589169_11	1382356.JQMP01000004_gene650	9.793e-19	97.0	2EDQP@1|root,337KB@2|Bacteria,2G9JE@200795|Chloroflexi,27YPT@189775|Thermomicrobia	189775|Thermomicrobia	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
YYD3_k127_1589169_1	867903.ThesuDRAFT_01401	2.955e-139	458.0	COG0348@1|root,COG0348@2|Bacteria,1U9JQ@1239|Firmicutes,24ADI@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
YYD3_k127_1589169_0	204669.Acid345_1692	2.791e-146	477.0	COG4585@1|root,COG4585@2|Bacteria,3Y3UD@57723|Acidobacteria,2JKVP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YYD3_k127_1589169_4	204669.Acid345_1691	6.282e-74	254.0	COG2197@1|root,COG2197@2|Bacteria,3Y4RA@57723|Acidobacteria,2JMRJ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_1594610_1	159087.Daro_2048	1.066e-115	383.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,Response_reg
YYD3_k127_1594610_0	234267.Acid_0085	1.366e-139	451.0	COG1132@1|root,COG1132@2|Bacteria,3Y6PT@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD3_k127_1597854_0	330084.JNYZ01000020_gene4708	1.234e-48	194.0	COG1506@1|root,COG1506@2|Bacteria,2I2J3@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Peptidase_S9
YYD3_k127_1597854_1	706587.Desti_5503	8.989e-33	138.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Spermine spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YYD3_k127_1615_16	1047013.AQSP01000108_gene2058	2.416e-42	167.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YYD3_k127_1615_18	204669.Acid345_2993	1.708e-17	88.0	2DR0H@1|root,339NS@2|Bacteria,3Y59F@57723|Acidobacteria,2JJP9@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Caa(3)-type oxidase, subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
YYD3_k127_1615_10	1340493.JNIF01000004_gene143	2.352e-75	259.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YYD3_k127_1615_1	234267.Acid_0498	5.835e-252	787.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YYD3_k127_1615_4	204669.Acid345_2996	2.703e-120	394.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
YYD3_k127_1615_9	204669.Acid345_2997	1.205e-75	265.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria,2JIUU@204432|Acidobacteriia	204432|Acidobacteriia	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
YYD3_k127_1615_20	1128421.JAGA01000003_gene2875	8.3e-11	73.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1615_5	234267.Acid_0494	4.526e-111	372.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria	57723|Acidobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1615_11	204669.Acid345_3000	1.577e-68	238.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_1615_14	1128421.JAGA01000003_gene2872	5.479e-63	221.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD3_k127_1615_2	1128421.JAGA01000003_gene2871	2.632e-210	662.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
YYD3_k127_1615_0	1128421.JAGA01000003_gene2870	0.0	1154.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
YYD3_k127_1615_8	234267.Acid_0489	3.973e-92	306.0	COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
YYD3_k127_1615_15	880073.Calab_1228	6.592e-53	194.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
YYD3_k127_1615_12	1429916.X566_21020	3.07e-65	229.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YYD3_k127_1615_3	555079.Toce_0176	3.932e-150	491.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,42EYY@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
YYD3_k127_1615_7	234267.Acid_1043	1.685e-101	344.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD3_k127_1615_19	400682.PAC_15706242	4.312e-15	79.0	COG2331@1|root,2SYQZ@2759|Eukaryota	2759|Eukaryota	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YYD3_k127_1615_6	234267.Acid_4336	5.205e-105	361.0	COG4805@1|root,COG4805@2|Bacteria,3Y47D@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YYD3_k127_1615_13	91464.S7335_2020	5.435e-65	233.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1GYBH@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YYD3_k127_1657788_1	502025.Hoch_1576	1.409e-48	180.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_1657788_0	1121918.ARWE01000001_gene3253	2.506e-135	440.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
YYD3_k127_1657788_2	1283299.AUKG01000002_gene5208	1.401e-25	107.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4CQN1@84995|Rubrobacteria	84995|Rubrobacteria	M	Large-conductance mechanosensitive channel, MscL	-	-	-	-	-	-	-	-	-	-	-	-	MscL
YYD3_k127_1684325_0	861299.J421_0319	2.558e-267	841.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
YYD3_k127_1684325_5	404589.Anae109_2807	2.135e-63	220.0	COG0346@1|root,COG0346@2|Bacteria,1MZD3@1224|Proteobacteria,434M2@68525|delta/epsilon subdivisions,2X8XQ@28221|Deltaproteobacteria,2Z0XI@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_1684325_6	448385.sce2665	5.633e-57	209.0	COG1335@1|root,COG1335@2|Bacteria,1MZP9@1224|Proteobacteria,42SNF@68525|delta/epsilon subdivisions,2X6IF@28221|Deltaproteobacteria,2Z22A@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YYD3_k127_1684325_4	1123504.JQKD01000022_gene75	1.652e-81	285.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2VHC0@28216|Betaproteobacteria,4AC17@80864|Comamonadaceae	28216|Betaproteobacteria	T	Gaf domain protein	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport,GAF_2
YYD3_k127_1684325_8	861299.J421_3958	6.868e-52	188.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
YYD3_k127_1684325_1	330084.JNYZ01000007_gene8710	2.446e-143	461.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4DZ52@85010|Pseudonocardiales	201174|Actinobacteria	IQ	short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
YYD3_k127_1684325_2	1434929.X946_3276	2.595e-104	355.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHD2@28216|Betaproteobacteria,1K0JI@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YYD3_k127_1684325_7	861299.J421_0647	5.047e-53	190.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_1684325_13	1134912.AJTV01000049_gene3635	1.482e-12	70.0	2DPU9@1|root,333E7@2|Bacteria,1N6Y7@1224|Proteobacteria,2UHW4@28211|Alphaproteobacteria,3711A@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	ko:K22014	-	-	-	-	ko00000	-	-	-	-
YYD3_k127_1684325_9	234267.Acid_4772	2.04e-48	175.0	COG1695@1|root,COG1695@2|Bacteria,3Y7WH@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_1684325_11	28229.ND2E_3439	3.577e-35	147.0	2EMAE@1|root,33EZF@2|Bacteria,1P1K8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1684325_3	1242864.D187_004525	1.536e-98	329.0	COG0863@1|root,COG0863@2|Bacteria,1Q6AU@1224|Proteobacteria,432RM@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
YYD3_k127_1684325_10	1430440.MGMSRv2_1582	2.009e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,1N1R7@1224|Proteobacteria,2UBVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YYD3_k127_1684325_12	685778.AORL01000019_gene1782	9.568e-33	130.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2TW1S@28211|Alphaproteobacteria,2K1QC@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_1711887_1	429009.Adeg_0526	2.508e-140	461.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YYD3_k127_1711887_15	1121406.JAEX01000007_gene2415	2.815e-05	56.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8VA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_1711887_5	945713.IALB_2604	5.323e-59	217.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD3_k127_1711887_12	682795.AciX8_3341	1.274e-07	62.0	2DDRA@1|root,2ZIZF@2|Bacteria,3Y956@57723|Acidobacteria,2JNTV@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1711887_13	378806.STAUR_7434	7.324e-07	60.0	COG1670@1|root,COG3170@1|root,COG1670@2|Bacteria,COG3170@2|Bacteria,1R3TU@1224|Proteobacteria,43E5S@68525|delta/epsilon subdivisions,2WZT9@28221|Deltaproteobacteria,2Z2PX@29|Myxococcales	28221|Deltaproteobacteria	NU	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin,Inhibitor_I36
YYD3_k127_1711887_2	234267.Acid_0081	1.881e-80	280.0	COG1409@1|root,COG1409@2|Bacteria,3Y6AF@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_1711887_8	382464.ABSI01000012_gene2041	2.811e-46	183.0	COG3004@1|root,COG3004@2|Bacteria,46XIZ@74201|Verrucomicrobia,2IW1K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1
YYD3_k127_1711887_0	756272.Plabr_3028	1.78e-231	732.0	COG2217@1|root,COG2217@2|Bacteria,2IXE1@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
YYD3_k127_1711887_9	357808.RoseRS_0607	3.829e-45	168.0	COG2010@1|root,COG2010@2|Bacteria,2G6R3@200795|Chloroflexi,377DZ@32061|Chloroflexia	32061|Chloroflexia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
YYD3_k127_1711887_6	1348657.M622_08260	1.102e-47	183.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria	1224|Proteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YYD3_k127_1711887_7	335543.Sfum_2497	2.421e-47	187.0	COG4591@1|root,COG4591@2|Bacteria,1RD9H@1224|Proteobacteria,43AMQ@68525|delta/epsilon subdivisions,2X61T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1711887_10	926550.CLDAP_36950	2.815e-34	150.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1711887_4	1303518.CCALI_02700	4.421e-59	221.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_1711887_11	1232410.KI421421_gene3612	2.362e-20	105.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,43RY1@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1711887_3	909663.KI867150_gene69	4.025e-60	215.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1725028_1	234267.Acid_3470	3.47e-176	580.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1725028_2	234267.Acid_7209	2.069e-48	175.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_1725028_0	1267535.KB906767_gene437	2.458e-316	1000.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria,2JI3C@204432|Acidobacteriia	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1725028_7	555793.WSK_4046	5.186e-13	74.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1725028_10	395965.Msil_0410	0.0006086	52.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1725028_5	247633.GP2143_17791	2.257e-20	102.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1725028_9	1122222.AXWR01000009_gene714	9.077e-10	66.0	2CBAE@1|root,32YK1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1725028_8	938709.AUSH02000031_gene1273	2.325e-12	78.0	2DBIE@1|root,32TXH@2|Bacteria,4NSJE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1725028_4	1082931.KKY_123	4.067e-22	108.0	2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1725028_6	103733.JNYO01000005_gene8606	4.823e-18	95.0	COG0454@1|root,COG0456@2|Bacteria,2HJGF@201174|Actinobacteria,4E0PN@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YYD3_k127_1725028_3	247633.GP2143_18131	2.804e-32	129.0	2C42J@1|root,3359Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1735528_5	627192.SLG_09880	2.713e-16	88.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1735528_7	204669.Acid345_3584	3.813e-13	75.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_1735528_4	317936.Nos7107_1461	4.053e-32	128.0	COG2442@1|root,COG2442@2|Bacteria,1G8FX@1117|Cyanobacteria,1HPIE@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YYD3_k127_1735528_8	251229.Chro_0246	4.8e-08	55.0	COG1598@1|root,COG1598@2|Bacteria,1G985@1117|Cyanobacteria,3VKSV@52604|Pleurocapsales	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YYD3_k127_1735528_3	1297742.A176_03023	5.34e-40	160.0	COG0596@1|root,COG0596@2|Bacteria,1MW2P@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_1735528_1	880072.Desac_2282	2.657e-182	601.0	COG1752@1|root,COG1752@2|Bacteria,1PGY0@1224|Proteobacteria,42MKJ@68525|delta/epsilon subdivisions,2WK4M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
YYD3_k127_1735528_6	868131.MSWAN_2224	1.326e-14	84.0	arCOG13037@1|root,arCOG13037@2157|Archaea,2Y5VI@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1735528_9	679926.Mpet_0462	7.625e-07	51.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y4NR@28890|Euryarchaeota,2NB66@224756|Methanomicrobia	224756|Methanomicrobia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
YYD3_k127_1735528_0	234267.Acid_3938	2.43e-190	625.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1735528_2	234267.Acid_7790	4.064e-102	337.0	COG0412@1|root,COG0412@2|Bacteria,3Y6ZZ@57723|Acidobacteria	57723|Acidobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
YYD3_k127_1737733_8	1267535.KB906767_gene1049	9.655e-51	185.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
YYD3_k127_1737733_10	1267535.KB906767_gene200	7.778e-37	143.0	COG1959@1|root,COG1959@2|Bacteria,3Y4X0@57723|Acidobacteria,2JJEV@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YYD3_k127_1737733_0	1267535.KB906767_gene199	1.027e-202	637.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD3_k127_1737733_5	1267535.KB906767_gene198	6.998e-66	228.0	COG0822@1|root,COG0822@2|Bacteria,3Y4B9@57723|Acidobacteria,2JJ45@204432|Acidobacteriia	204432|Acidobacteriia	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YYD3_k127_1737733_13	1382359.JIAL01000001_gene823	1.634e-31	127.0	COG0316@1|root,COG0316@2|Bacteria,3Y518@57723|Acidobacteria,2JJGN@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YYD3_k127_1737733_11	1382359.JIAL01000001_gene824	1.897e-34	142.0	COG1076@1|root,COG1076@2|Bacteria,3Y4MR@57723|Acidobacteria,2JJBF@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM heat shock protein DnaJ	-	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
YYD3_k127_1737733_1	744872.Spica_2740	4.117e-169	554.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YYD3_k127_1737733_9	1267535.KB906767_gene1459	3.554e-45	168.0	COG0633@1|root,COG0633@2|Bacteria,3Y4T7@57723|Acidobacteria,2JJFT@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
YYD3_k127_1737733_14	240015.ACP_2551	2.608e-21	94.0	COG2975@1|root,COG2975@2|Bacteria,3Y5I4@57723|Acidobacteria,2JJZY@204432|Acidobacteriia	204432|Acidobacteriia	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
YYD3_k127_1737733_7	247490.KSU1_C1155	1.434e-53	197.0	COG0775@1|root,COG0775@2|Bacteria,2J4NX@203682|Planctomycetes	203682|Planctomycetes	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
YYD3_k127_1737733_2	1150600.ADIARSV_2432	3.651e-108	356.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YYD3_k127_1737733_3	1122604.JONR01000011_gene3715	9.948e-97	333.0	COG0614@1|root,COG0614@2|Bacteria,1PK1A@1224|Proteobacteria,1RRDK@1236|Gammaproteobacteria,1X3UZ@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC transporter substrate-binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD3_k127_1737733_4	1382359.JIAL01000001_gene1727	6.68e-80	276.0	COG2102@1|root,COG2102@2|Bacteria,3Y46Z@57723|Acidobacteria,2JIS5@204432|Acidobacteriia	204432|Acidobacteriia	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
YYD3_k127_1737733_12	502025.Hoch_0419	4.333e-32	139.0	COG4558@1|root,COG4558@2|Bacteria,1QTSV@1224|Proteobacteria,43CYE@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Periplasmic binding protein	hmuT	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD3_k127_1737733_6	1026882.MAMP_02936	1.11e-62	224.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,460DW@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
YYD3_k127_1744268_0	1267535.KB906767_gene5005	2.603e-114	380.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YYD3_k127_1744268_1	1267535.KB906767_gene1985	6.992e-40	151.0	COG0640@1|root,COG0640@2|Bacteria,3Y5ZP@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
YYD3_k127_1744268_2	555793.WSK_2321	8.334e-07	55.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1744686_1	234267.Acid_7680	1.659e-86	292.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1744686_3	1126627.BAWE01000002_gene553	5.268e-13	71.0	2BUZT@1|root,32QCC@2|Bacteria,1Q8TE@1224|Proteobacteria,2UYDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1744686_2	1187851.A33M_4394	3.094e-54	194.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_1744686_0	1303518.CCALI_00822	4.361e-97	327.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
YYD3_k127_1749209_0	743836.AYNA01000080_gene2797	1.68e-77	271.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,370UH@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
YYD3_k127_1753356_0	1340493.JNIF01000003_gene1819	3.152e-153	546.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
YYD3_k127_1753356_2	1340493.JNIF01000003_gene1818	6.529e-07	59.0	COG0457@1|root,COG0457@2|Bacteria	1340493.JNIF01000003_gene1818|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1753356_1	388051.AUFE01000004_gene926	1.003e-42	160.0	COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2VUFU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
YYD3_k127_1779980_3	945713.IALB_0790	2.355e-146	473.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	dapE	-	3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_1779980_20	485913.Krac_12168	1.471e-43	176.0	COG0491@1|root,COG0491@2|Bacteria,2G8W8@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1779980_17	479435.Kfla_2262	7.104e-52	193.0	COG1183@1|root,COG1183@2|Bacteria,2IC3M@201174|Actinobacteria,4DRZ8@85009|Propionibacteriales	201174|Actinobacteria	I	phosphatidylcholine synthase	pcs	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YYD3_k127_1779980_8	309801.trd_A0275	5.277e-96	332.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
YYD3_k127_1779980_19	671143.DAMO_2862	1.685e-46	173.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	def2	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YYD3_k127_1779980_16	266117.Rxyl_0013	2.4e-52	190.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudC_1	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
YYD3_k127_1779980_1	945713.IALB_0026	1.094e-169	539.0	COG1830@1|root,COG1830@2|Bacteria	2|Bacteria	G	lyase activity	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
YYD3_k127_1779980_5	330214.NIDE1125	1.52e-119	400.0	COG0301@1|root,COG0301@2|Bacteria	2|Bacteria	H	tRNA thio-modification	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
YYD3_k127_1779980_15	391625.PPSIR1_11225	2.164e-66	243.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria	1224|Proteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
YYD3_k127_1779980_14	671143.DAMO_1512	6.205e-67	241.0	COG1562@1|root,COG1562@2|Bacteria,2NQ19@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
YYD3_k127_1779980_13	1123368.AUIS01000001_gene2032	1.076e-70	250.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
YYD3_k127_1779980_18	290397.Adeh_3476	1.474e-50	195.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
YYD3_k127_1779980_11	330214.NIDE1914	1.977e-89	299.0	COG1194@1|root,COG1194@2|Bacteria,3J160@40117|Nitrospirae	40117|Nitrospirae	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD3_k127_1779980_23	880073.Calab_1124	9.899e-24	115.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
YYD3_k127_1779980_22	929712.KI912613_gene3241	5.035e-37	161.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
YYD3_k127_1779980_21	379066.GAU_3598	8.7e-40	167.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
YYD3_k127_1779980_7	1267535.KB906767_gene5433	2.679e-99	331.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
YYD3_k127_1779980_10	1267535.KB906767_gene5432	4.827e-90	304.0	COG0414@1|root,COG0414@2|Bacteria,3Y40A@57723|Acidobacteria,2JHS1@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
YYD3_k127_1779980_9	477184.KYC_24392	7.933e-96	329.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria	28216|Betaproteobacteria	EQ	PFAM peptidase S58, DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
YYD3_k127_1779980_4	379066.GAU_3550	1.313e-120	402.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
YYD3_k127_1779980_2	379066.GAU_3552	6.529e-158	505.0	COG0473@1|root,COG0473@2|Bacteria,1ZTDX@142182|Gemmatimonadetes	2|Bacteria	C	Isocitrate/isopropylmalate dehydrogenase	ttuC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006108,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009027,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_1288,ic_1306.c2207	Iso_dh
YYD3_k127_1779980_0	1122223.KB890697_gene1024	1.888e-185	590.0	COG1690@1|root,COG1690@2|Bacteria,1WMKR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
YYD3_k127_1779980_12	1121920.AUAU01000013_gene1734	9.341e-80	275.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	MTS
YYD3_k127_1779980_6	926549.KI421517_gene2223	5.871e-110	385.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YYD3_k127_1784613_5	937777.Deipe_3720	2.99e-08	60.0	29UQ5@1|root,30G1W@2|Bacteria	2|Bacteria	C	spheroidene monooxygenase	crtA	-	1.14.15.9	ko:K09847	ko00906,ko01100,map00906,map01100	-	R07525,R07526,R07537,R07538	RC02084	ko00000,ko00001,ko01000	-	-	-	DUF3291
YYD3_k127_1784613_2	192952.MM_0503	1.564e-50	190.0	COG1266@1|root,arCOG02768@2157|Archaea,2XYFG@28890|Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD3_k127_1784613_3	404589.Anae109_0256	1.583e-43	167.0	2DYDA@1|root,34983@2|Bacteria,1N38S@1224|Proteobacteria,4318W@68525|delta/epsilon subdivisions,2WWC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_1784613_1	861299.J421_0475	1.819e-60	215.0	COG1595@1|root,COG1595@2|Bacteria,1ZUZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_1784613_0	861299.J421_0476	1.659e-272	864.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZTK4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
YYD3_k127_1787693_1	234267.Acid_2289	6.388e-213	681.0	COG2303@1|root,COG4993@1|root,COG2303@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2,1.1.5.9	ko:K00117,ko:K19813	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R00305,R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,PQQ,PQQ_2
YYD3_k127_1787693_3	234267.Acid_4011	6.405e-100	342.0	COG3503@1|root,COG3503@2|Bacteria,3Y3XK@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
YYD3_k127_1787693_4	1163408.UU9_07526	2.075e-55	216.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1X6PT@135614|Xanthomonadales	135614|Xanthomonadales	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
YYD3_k127_1787693_0	886293.Sinac_4683	1.395e-271	850.0	COG0457@1|root,COG0457@2|Bacteria	886293.Sinac_4683|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
YYD3_k127_1787693_9	1384056.N787_06750	3.901e-32	130.0	29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,1SB4D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
YYD3_k127_1787693_8	671143.DAMO_0438	6.095e-36	139.0	COG2350@1|root,COG2350@2|Bacteria,2NR74@2323|unclassified Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
YYD3_k127_1787693_6	1340493.JNIF01000003_gene3979	6.812e-44	165.0	COG5507@1|root,COG5507@2|Bacteria,3Y82V@57723|Acidobacteria	57723|Acidobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
YYD3_k127_1787693_7	945713.IALB_1910	7.294e-42	168.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5,Acyl_transf_3,DUF1624
YYD3_k127_1787693_2	1379270.AUXF01000001_gene2303	9.437e-181	591.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
YYD3_k127_1787693_5	1379270.AUXF01000001_gene2302	6.103e-48	186.0	COG4249@1|root,COG4249@2|Bacteria,1ZUQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1793099_13	234267.Acid_0107	5.558e-25	106.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_1793099_11	1499967.BAYZ01000193_gene3921	5.79e-84	290.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
YYD3_k127_1793099_3	1089553.Tph_c02150	1.532e-162	518.0	COG2006@1|root,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,42F8W@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
YYD3_k127_1793099_7	1047013.AQSP01000140_gene2461	1.258e-115	387.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
YYD3_k127_1793099_12	1499967.BAYZ01000038_gene2273	4.386e-64	235.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
YYD3_k127_1793099_5	204669.Acid345_3356	4.935e-138	454.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_1793099_1	204669.Acid345_3357	1.032e-172	577.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
YYD3_k127_1793099_14	401053.AciPR4_2114	4.202e-05	57.0	COG3485@1|root,COG3485@2|Bacteria,3Y44E@57723|Acidobacteria,2JIGS@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1793099_15	682795.AciX8_3035	5.108e-05	51.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1793099_4	330214.NIDE1796	9.53e-153	495.0	COG0448@1|root,COG0448@2|Bacteria,3J0BI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD3_k127_1793099_2	886293.Sinac_7515	1.053e-166	535.0	COG0148@1|root,COG0148@2|Bacteria,2IXRG@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YYD3_k127_1793099_6	234267.Acid_4374	8.572e-118	383.0	COG0588@1|root,COG0588@2|Bacteria,3Y6SZ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YYD3_k127_1793099_0	340099.Teth39_0902	6.586e-213	672.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YYD3_k127_1793099_10	644966.Tmar_1340	3.712e-93	313.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YYD3_k127_1793099_9	1444309.JAQG01000073_gene256	1.808e-99	333.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,26QEH@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
YYD3_k127_1793099_8	1267535.KB906767_gene3077	1.047e-101	335.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_1804865_0	1121920.AUAU01000004_gene813	1.727e-143	470.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
YYD3_k127_1804865_1	521674.Plim_1577	6.605e-22	99.0	COG1028@1|root,COG1028@2|Bacteria,2IXK3@203682|Planctomycetes	203682|Planctomycetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
YYD3_k127_1812648_2	1123392.AQWL01000005_gene2891	8.549e-28	114.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1KRW4@119069|Hydrogenophilales	119069|Hydrogenophilales	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YYD3_k127_1812648_1	1242864.D187_003185	2.125e-38	162.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,42XQG@68525|delta/epsilon subdivisions,2WT9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
YYD3_k127_1812648_0	861299.J421_5667	8.938e-125	409.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
YYD3_k127_1817256_4	1173028.ANKO01000214_gene6278	1.526e-98	333.0	COG0840@1|root,COG0840@2|Bacteria,1G4MY@1117|Cyanobacteria,1HA77@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
YYD3_k127_1817256_16	1173029.JH980292_gene2725	6.042e-43	167.0	COG0835@1|root,COG0835@2|Bacteria,1G7FI@1117|Cyanobacteria,1HBXN@1150|Oscillatoriales	1117|Cyanobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YYD3_k127_1817256_0	1173022.Cri9333_3522	4.68e-181	593.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1G26V@1117|Cyanobacteria,1HABC@1150|Oscillatoriales	1117|Cyanobacteria	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
YYD3_k127_1817256_19	861299.J421_5918	9.621e-40	151.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_5918|-	T	phosphorelay signal transduction system	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	-
YYD3_k127_1817256_20	285535.JOEY01000010_gene6327	1.635e-33	138.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YYD3_k127_1817256_24	1090318.ATTI01000001_gene970	7.727e-17	90.0	COG3258@1|root,COG3258@2|Bacteria,1R0F2@1224|Proteobacteria,2TYQH@28211|Alphaproteobacteria,2K6ZI@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_1817256_11	1459636.NTE_03052	3.157e-49	180.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_1817256_3	861299.J421_0616	2.865e-104	351.0	COG0272@1|root,COG0515@1|root,COG0272@2|Bacteria,COG0515@2|Bacteria	2|Bacteria	KLT	protein kinase activity	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	2.7.7.7,6.5.1.2	ko:K01972,ko:K02342,ko:K04096	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378,R00382	RC00005,RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,DNA_processg_A,HHH_2,HHH_5,RNase_T
YYD3_k127_1817256_6	234267.Acid_3227	1.77e-88	314.0	COG2857@1|root,COG2857@2|Bacteria	2|Bacteria	C	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_5	1038858.AXBA01000003_gene4276	4.965e-94	314.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2U5V7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
YYD3_k127_1817256_22	404380.Gbem_2013	2.458e-30	123.0	2DQJB@1|root,3377V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_14	1335760.ASTG01000005_gene981	5.106e-47	175.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_9	525368.HMPREF0591_0516	3.39e-74	271.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,234HP@1762|Mycobacteriaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
YYD3_k127_1817256_2	404589.Anae109_3248	5.603e-112	371.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria	1224|Proteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
YYD3_k127_1817256_21	234267.Acid_2952	1.786e-32	140.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YYD3_k127_1817256_10	234267.Acid_2953	4.229e-66	237.0	COG2304@1|root,COG2304@2|Bacteria,3Y7U1@57723|Acidobacteria	2|Bacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
YYD3_k127_1817256_23	234267.Acid_2955	3.107e-17	93.0	2FBCE@1|root,343I9@2|Bacteria,3Y8Q4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_15	1082931.KKY_83	1.107e-45	184.0	28JDP@1|root,32SV2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_13	994479.GL877878_gene1192	1.89e-47	172.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria,4E51J@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_1817256_1	479435.Kfla_6234	2.905e-164	533.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DN3F@85009|Propionibacteriales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_1817256_18	551789.ATVJ01000001_gene1039	1.206e-41	157.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_12	247633.GP2143_18126	3.215e-48	188.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_8	247633.GP2143_17791	5.651e-81	283.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_17	643648.Slip_0781	1.371e-42	179.0	COG0613@1|root,COG0613@2|Bacteria,1UVWH@1239|Firmicutes,2592Y@186801|Clostridia,42KDK@68298|Syntrophomonadaceae	186801|Clostridia	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1817256_7	1187851.A33M_1157	1.287e-82	282.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,3FCQP@34008|Rhodovulum	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YYD3_k127_1818358_11	204669.Acid345_1319	5.922e-12	72.0	COG0789@1|root,COG0789@2|Bacteria,3Y5EZ@57723|Acidobacteria,2JN9T@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
YYD3_k127_1818358_5	561175.KB894108_gene4879	4.635e-62	229.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4EH02@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
YYD3_k127_1818358_3	1340493.JNIF01000003_gene3519	3.228e-81	302.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_1818358_2	234267.Acid_1102	8.514e-90	319.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD3_k127_1818358_4	234267.Acid_1101	5.863e-81	276.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_1818358_8	234267.Acid_6678	2.793e-24	113.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1818358_10	243090.RB1240	8.959e-13	76.0	COG3453@1|root,COG3453@2|Bacteria,2J4Z0@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YYD3_k127_1818358_0	204669.Acid345_4566	2.562e-152	491.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.metX	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YYD3_k127_1818358_6	1183438.GKIL_4142	1.362e-52	188.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
YYD3_k127_1818358_9	278963.ATWD01000001_gene3461	5.974e-23	103.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria,2JJ4E@204432|Acidobacteriia	204432|Acidobacteriia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD3_k127_1818358_7	204669.Acid345_3681	3.223e-36	139.0	COG0139@1|root,COG0139@2|Bacteria,3Y4SN@57723|Acidobacteria,2JJIB@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	-	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
YYD3_k127_1818358_1	234267.Acid_3856	4.416e-122	398.0	COG0040@1|root,COG0040@2|Bacteria,3Y31Q@57723|Acidobacteria	57723|Acidobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
YYD3_k127_1818358_12	1227739.Hsw_2178	7.733e-06	55.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,47JSY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YYD3_k127_1844036_1	234267.Acid_5112	9.962e-95	314.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YYD3_k127_1844036_6	240015.ACP_1446	4.204e-25	109.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria,2JJ8K@204432|Acidobacteriia	204432|Acidobacteriia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YYD3_k127_1844036_5	240015.ACP_1447	6.069e-40	152.0	COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria,2JJMI@204432|Acidobacteriia	204432|Acidobacteriia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YYD3_k127_1844036_0	204669.Acid345_1229	4.447e-121	394.0	COG0090@1|root,COG0090@2|Bacteria,3Y3DH@57723|Acidobacteria,2JI2K@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YYD3_k127_1844036_7	1267534.KB906757_gene819	2.057e-24	106.0	COG0089@1|root,COG0089@2|Bacteria,3Y58W@57723|Acidobacteria,2JJR2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YYD3_k127_1844036_3	1267535.KB906767_gene2703	8.608e-54	205.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria,2JIZE@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YYD3_k127_1844036_2	234267.Acid_5118	6.772e-78	267.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YYD3_k127_1844036_4	204669.Acid345_1225	1.737e-52	187.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YYD3_k127_1844036_8	716544.wcw_0584	2.319e-19	87.0	COG0050@1|root,COG0050@2|Bacteria,2JFRG@204428|Chlamydiae	204428|Chlamydiae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD3_k127_1865892_1	290397.Adeh_1029	8.913e-58	210.0	COG0500@1|root,COG2226@2|Bacteria,1PEZM@1224|Proteobacteria,434HR@68525|delta/epsilon subdivisions,2X8WH@28221|Deltaproteobacteria,2Z0PT@29|Myxococcales	28221|Deltaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_1865892_5	314278.NB231_04047	1.502e-08	58.0	2AI8M@1|root,318P7@2|Bacteria,1PAB9@1224|Proteobacteria	1224|Proteobacteria	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
YYD3_k127_1865892_0	709986.Deima_0904	1.586e-81	294.0	COG2133@1|root,COG2133@2|Bacteria,1WMHH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	COGs COG2133 Glucose sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_1865892_4	1219035.NT2_11_00380	9.915e-13	75.0	COG2010@1|root,COG2010@2|Bacteria,1N7I9@1224|Proteobacteria,2V1R3@28211|Alphaproteobacteria,2KBX4@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1865892_3	391587.KAOT1_01235	1.603e-14	84.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1865892_2	756272.Plabr_3437	8.157e-19	98.0	COG2010@1|root,COG2010@2|Bacteria,2J3TA@203682|Planctomycetes	203682|Planctomycetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
YYD3_k127_1870523_1	344747.PM8797T_21603	6.463e-09	58.0	COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_1870523_0	344747.PM8797T_21598	2.872e-160	518.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_1893659_5	483219.LILAB_31320	2.031e-59	231.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
YYD3_k127_1893659_4	671143.DAMO_2311	1.781e-65	230.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
YYD3_k127_1893659_2	204669.Acid345_4701	5.057e-104	346.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD3_k127_1893659_3	330214.NIDE1579	1.577e-74	273.0	COG0285@1|root,COG0285@2|Bacteria,3J0I6@40117|Nitrospirae	40117|Nitrospirae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YYD3_k127_1893659_6	1047013.AQSP01000138_gene1041	1.298e-54	218.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659	-	ko:K04744,ko:K09774,ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2,1.B.42.1	-	iAF987.Gmet_2474,iECO111_1330.ECO111_4695,iECSF_1327.ECSF_3725,iEcSMS35_1347.EcSMS35_4260	KdgM,OstA,OstA_2,OstA_C
YYD3_k127_1893659_0	1047013.AQSP01000144_gene874	2.158e-149	483.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
YYD3_k127_1893659_1	247490.KSU1_C0923	3.562e-115	391.0	COG1088@1|root,COG1088@2|Bacteria,2IY3D@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_1973915_2	59538.XP_005981185.1	6.374e-23	104.0	2CMC3@1|root,2QPXZ@2759|Eukaryota,38CYT@33154|Opisthokonta	33154|Opisthokonta	G	feruloyl esterase activity	faeB-1	GO:0000272,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010393,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0016998,GO:0017144,GO:0030600,GO:0042737,GO:0042802,GO:0042803,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0045488,GO:0045490,GO:0045491,GO:0045493,GO:0046983,GO:0052689,GO:0071554,GO:0071704,GO:1901575	3.1.1.73	ko:K09252	-	-	-	-	ko00000,ko01000	-	-	-	Tannase
YYD3_k127_1973915_0	1121377.KB906405_gene135	9.09e-130	432.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YYD3_k127_1973915_1	649638.Trad_2529	1.356e-62	224.0	COG1028@1|root,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD3_k127_1979912_2	401053.AciPR4_3363	4.737e-45	178.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1979912_3	234267.Acid_2558	3.575e-38	151.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_1979912_0	234267.Acid_2557	5.575e-274	864.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_1979912_1	1379270.AUXF01000002_gene1145	1.756e-104	357.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_1980066_3	1123499.KB908028_gene102	4.592e-23	114.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VP3I@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_1980066_2	1124780.ANNU01000074_gene751	1.464e-30	134.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_1980066_0	234267.Acid_7368	6.321e-84	292.0	COG2220@1|root,COG2220@2|Bacteria,3Y2TV@57723|Acidobacteria	57723|Acidobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YYD3_k127_1980066_1	663610.JQKO01000012_gene3076	1.754e-44	178.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1983765_0	85643.Tmz1t_0222	2.543e-149	481.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VIFB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	cobS	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CobS_N
YYD3_k127_1983765_1	1313172.YM304_14100	1.073e-105	346.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4CN01@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
YYD3_k127_1983765_2	234267.Acid_2366	1.245e-09	69.0	COG0789@1|root,COG0789@2|Bacteria,3Y4XP@57723|Acidobacteria	57723|Acidobacteria	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
YYD3_k127_1987139_3	1169143.KB911037_gene3943	9.62e-17	80.0	COG3408@1|root,COG3408@2|Bacteria,1QUN2@1224|Proteobacteria,2WHH3@28216|Betaproteobacteria,1KIP3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
YYD3_k127_1987139_2	234267.Acid_1777	9.04e-92	322.0	COG0668@1|root,COG0668@2|Bacteria,3Y6BI@57723|Acidobacteria	57723|Acidobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
YYD3_k127_1987139_0	1202532.FF52_04800	3.725e-153	512.0	COG5164@1|root,COG5164@2|Bacteria,4NFN0@976|Bacteroidetes,1IMWB@117743|Flavobacteriia,2NVM5@237|Flavobacterium	976|Bacteroidetes	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1987139_4	1318628.MARLIPOL_12999	4.059e-12	76.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1SGG7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
YYD3_k127_1987139_1	398767.Glov_0364	3.095e-112	387.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
YYD3_k127_2013501_10	682795.AciX8_3013	1.153e-16	81.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria,2JKRT@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_2013501_12	1340493.JNIF01000003_gene2122	2.869e-12	72.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2013501_11	1122223.KB890696_gene78	1.717e-15	88.0	COG2010@1|root,COG2010@2|Bacteria,1WN9N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_2013501_6	497321.C664_09853	2.409e-46	172.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,2VRVD@28216|Betaproteobacteria,2KWIM@206389|Rhodocyclales	206389|Rhodocyclales	E	Glycine cleavage system regulatory protein	gcvR	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
YYD3_k127_2013501_13	1165096.ARWF01000001_gene441	7.821e-05	51.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2013501_5	926566.Terro_0915	1.412e-56	203.0	2CGTC@1|root,331SF@2|Bacteria,3Y7P6@57723|Acidobacteria,2JMRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD3_k127_2013501_7	450851.PHZ_c3077	5.31e-43	171.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2013501_2	861299.J421_0285	9.214e-151	515.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0285|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2013501_4	1210884.HG799466_gene12816	2.3e-65	248.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_2013501_3	1267533.KB906733_gene3355	1.63e-116	407.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2013501_14	1121033.AUCF01000005_gene5128	0.0001563	52.0	COG3637@1|root,COG3637@2|Bacteria,1N2XM@1224|Proteobacteria,2UMEY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
YYD3_k127_2013501_1	518766.Rmar_0629	7.558e-171	573.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
YYD3_k127_2013501_8	1444310.JANV01000091_gene4175	3.227e-29	126.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HF93@91061|Bacilli,1ZPV8@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	pdaC	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
YYD3_k127_2013501_9	136993.KB900627_gene392	3.436e-28	124.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2013501_0	1301098.PKB_3948	2.598e-304	952.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	lhr	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
YYD3_k127_2021143_1	999541.bgla_2g17310	1.067e-48	178.0	COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria,2VUD7@28216|Betaproteobacteria,1KASE@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_2021143_0	240015.ACP_2643	3.805e-106	347.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YYD3_k127_2022849_6	234267.Acid_3603	2.503e-45	167.0	COG1595@1|root,COG1595@2|Bacteria,3Y5BP@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2022849_1	400682.PAC_15708170	6.642e-176	561.0	COG0160@1|root,KOG1404@2759|Eukaryota,38EI2@33154|Opisthokonta,3BWYI@33208|Metazoa	33208|Metazoa	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
YYD3_k127_2022849_0	1120934.KB894404_gene746	8.185e-199	642.0	COG1520@1|root,COG1680@1|root,COG1520@2|Bacteria,COG1680@2|Bacteria,2HSCZ@201174|Actinobacteria,4EDAG@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2022849_3	323259.Mhun_2065	4.513e-72	262.0	COG1233@1|root,arCOG01521@2157|Archaea,2Y1KE@28890|Euryarchaeota	28890|Euryarchaeota	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
YYD3_k127_2022849_5	671143.DAMO_0449	3.529e-48	196.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3367,DUF5122,HemolysinCabind,NPCBM
YYD3_k127_2022849_12	395965.Msil_1295	0.0001344	46.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_2022849_2	234267.Acid_3734	2.588e-73	257.0	COG1735@1|root,COG1735@2|Bacteria,3Y646@57723|Acidobacteria	57723|Acidobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2022849_4	234267.Acid_2447	2.171e-70	253.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_2022849_11	69395.JQLZ01000004_gene582	5.386e-05	55.0	COG0662@1|root,COG0662@2|Bacteria,1NVCR@1224|Proteobacteria,2URU1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
YYD3_k127_2022849_8	551789.ATVJ01000001_gene1037	1.187e-40	163.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2022849_7	247633.GP2143_17796	1.145e-44	180.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2043186_3	1125863.JAFN01000001_gene2149	5.197e-65	229.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
YYD3_k127_2043186_2	639030.JHVA01000001_gene1281	8.808e-95	342.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y6C4@57723|Acidobacteria,2JM8A@204432|Acidobacteriia	204432|Acidobacteriia	E	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2043186_8	484770.UFO1_1519	4.608e-24	111.0	COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4H4RM@909932|Negativicutes	909932|Negativicutes	S	Isoprenylcysteine carboxyl methyltransferase	-	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
YYD3_k127_2043186_7	671143.DAMO_0700	1.282e-35	150.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	fixC	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
YYD3_k127_2043186_1	886293.Sinac_7060	9.925e-122	405.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YYD3_k127_2043186_10	395961.Cyan7425_2945	8.123e-17	91.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
YYD3_k127_2043186_9	639030.JHVA01000001_gene1715	5.438e-19	91.0	2BYAI@1|root,315Y9@2|Bacteria,3Y52S@57723|Acidobacteria,2JJJK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2043186_0	269799.Gmet_3214	4.583e-247	786.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_2043186_4	1232410.KI421412_gene406	9.706e-65	235.0	COG1193@1|root,COG1193@2|Bacteria,1QYV7@1224|Proteobacteria	1224|Proteobacteria	L	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2043186_5	234267.Acid_5489	2.944e-60	237.0	COG0457@1|root,COG4219@1|root,COG0457@2|Bacteria,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
YYD3_k127_2043186_6	234267.Acid_5488	7.992e-39	147.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_2079174_1	392499.Swit_3080	2.12e-134	457.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2K1GK@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_2079174_0	1267533.KB906733_gene3563	2.035e-155	513.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
YYD3_k127_2079174_3	937777.Deipe_1304	4.44e-30	130.0	COG1917@1|root,COG1917@2|Bacteria,1WMIY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2079174_4	1183438.GKIL_3396	1.132e-29	120.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
YYD3_k127_2094644_9	102129.Lepto7375DRAFT_2567	2.776e-18	100.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14,Trypsin_2
YYD3_k127_2094644_4	344747.PM8797T_21598	1.411e-83	305.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_2094644_3	706587.Desti_1404	2.35e-130	443.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
YYD3_k127_2094644_1	1267533.KB906733_gene3429	6.583e-158	504.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YYD3_k127_2094644_2	1267534.KB906754_gene2651	2.147e-150	484.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD3_k127_2094644_7	1267533.KB906735_gene4737	1.325e-26	115.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2094644_5	234267.Acid_1441	3.336e-64	236.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_2094644_6	234267.Acid_1440	1.242e-58	213.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
YYD3_k127_2094644_8	1392498.JQLH01000001_gene1011	5.559e-22	112.0	COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia,2PI1V@252356|Maribacter	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
YYD3_k127_2102920_0	234267.Acid_5749	2.18e-126	420.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2102920_1	1267533.KB906733_gene3563	4.093e-125	416.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
YYD3_k127_2154075_2	700598.Niako_4637	1.709e-31	138.0	2CYFR@1|root,32T44@2|Bacteria,4P6IN@976|Bacteroidetes,1IZDY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
YYD3_k127_2154075_1	1282361.ABAC402_17780	4.028e-37	155.0	2CK59@1|root,32VV2@2|Bacteria,1P616@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2154075_0	864051.BurJ1DRAFT_2134	1.297e-41	161.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2VVI3@28216|Betaproteobacteria,1KP7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2168513_0	861299.J421_1758	5.414e-188	604.0	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YYD3_k127_2184395_3	1040989.AWZU01000008_gene3756	1.297e-28	117.0	COG0642@1|root,COG2205@2|Bacteria,1N5YU@1224|Proteobacteria,2TTXK@28211|Alphaproteobacteria,3K5Y2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_2184395_1	861299.J421_1935	4.477e-260	826.0	COG2091@1|root,COG2091@2|Bacteria,1ZU9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2184395_0	1266925.JHVX01000006_gene2125	0.0	1477.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2VJBD@28216|Betaproteobacteria,372I3@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DUF1080,FAD_binding_2,GMC_oxred_C
YYD3_k127_2184395_2	748247.AZKH_2190	8.864e-35	134.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.178,2.3.1.183	ko:K03823,ko:K06718	ko00260,ko00440,ko01100,ko01120,ko01130,map00260,map00440,map01100,map01120,map01130	M00033	R06978,R08871,R08938	RC00004,RC00064,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
YYD3_k127_218532_1	1198114.AciX9_0630	2.691e-57	205.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
YYD3_k127_218532_0	479434.Sthe_2627	4.65e-106	356.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,27Y3V@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_218532_2	671143.DAMO_2591	4.445e-32	141.0	2E0UX@1|root,32WC9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YYD3_k127_218532_3	1242864.D187_005579	2.008e-14	79.0	COG3055@1|root,COG3209@1|root,COG3055@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2YUH1@29|Myxococcales	28221|Deltaproteobacteria	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
YYD3_k127_2192496_6	97139.C824_01589	5.788e-51	188.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,36DHM@31979|Clostridiaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YYD3_k127_2192496_5	1379698.RBG1_1C00001G0930	1.699e-59	214.0	COG0432@1|root,COG0432@2|Bacteria,2NPB7@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD3_k127_2192496_7	204669.Acid345_1350	6.976e-38	147.0	COG1051@1|root,COG1051@2|Bacteria,3Y5BM@57723|Acidobacteria,2JJTC@204432|Acidobacteriia	204432|Acidobacteriia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_2192496_4	204669.Acid345_1412	2.713e-68	237.0	COG2316@1|root,COG2316@2|Bacteria,3Y4GI@57723|Acidobacteria,2JJBG@204432|Acidobacteriia	204432|Acidobacteriia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
YYD3_k127_2192496_1	1047013.AQSP01000128_gene416	1.532e-96	325.0	COG1131@1|root,COG1131@2|Bacteria,2NQRI@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_2192496_9	1047013.AQSP01000128_gene415	1.419e-26	119.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
YYD3_k127_2192496_2	1210884.HG799462_gene8051	3.177e-95	321.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YYD3_k127_2192496_8	1047013.AQSP01000128_gene413	1.66e-27	125.0	2DU2Y@1|root,33NQT@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
YYD3_k127_2192496_12	1254432.SCE1572_22840	7.799e-06	57.0	COG1404@1|root,COG1404@2|Bacteria,1PBYF@1224|Proteobacteria,4386G@68525|delta/epsilon subdivisions,2X3GD@28221|Deltaproteobacteria,2YVZB@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2192496_10	1122605.KB893646_gene140	7.836e-11	68.0	COG2105@1|root,COG2105@2|Bacteria,4NUSS@976|Bacteroidetes,1IZG0@117747|Sphingobacteriia	976|Bacteroidetes	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
YYD3_k127_2192496_13	748247.AZKH_0194	0.0001409	52.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVEE@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
YYD3_k127_2192496_0	1379698.RBG1_1C00001G0471	2.672e-225	707.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD3_k127_2192496_3	903818.KI912268_gene2181	4.259e-75	284.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_2192496_11	1340493.JNIF01000003_gene3549	8.566e-10	63.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_2192721_6	1209072.ALBT01000032_gene2124	4.997e-25	113.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2192721_5	1382306.JNIM01000001_gene1216	1.921e-48	176.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
YYD3_k127_2192721_3	1000565.METUNv1_01254	2.599e-56	199.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VTA1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_2192721_7	330214.NIDE1012	6.42e-08	61.0	COG1714@1|root,COG1714@2|Bacteria,3J0U3@40117|Nitrospirae	40117|Nitrospirae	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
YYD3_k127_2192721_0	1123277.KB893176_gene3687	2.523e-299	939.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
YYD3_k127_2192721_2	234267.Acid_5036	7.998e-90	336.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
YYD3_k127_2192721_4	234267.Acid_5940	9.271e-52	212.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_2192721_1	935840.JAEQ01000009_gene1380	7.599e-157	513.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
YYD3_k127_2192721_8	204669.Acid345_0263	0.0004308	46.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_2195864_0	498761.HM1_2138	1.152e-46	191.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
YYD3_k127_2195864_1	196490.AUEZ01000094_gene5850	1.567e-05	53.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,3JR7Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	symbiont process	nolO	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YYD3_k127_2244994_7	1340493.JNIF01000004_gene123	0.0002075	48.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM
YYD3_k127_2244994_1	1191523.MROS_1496	7.927e-171	547.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_2244994_2	1191523.MROS_1497	4.254e-125	416.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_2244994_6	861299.J421_5835	4.941e-27	116.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_2244994_3	404589.Anae109_3508	1.721e-64	231.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Asparaginase	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
YYD3_k127_2244994_4	1499967.BAYZ01000158_gene443	5.83e-57	206.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
YYD3_k127_2244994_0	379066.GAU_3538	5.774e-190	622.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
YYD3_k127_2244994_5	997346.HMPREF9374_2150	4.536e-29	123.0	COG0165@1|root,COG0165@2|Bacteria,1U4V0@1239|Firmicutes,4HE7Q@91061|Bacilli,27CIX@186824|Thermoactinomycetaceae	91061|Bacilli	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
YYD3_k127_2253419_1	234267.Acid_2447	1.094e-81	282.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_2253419_0	316067.Geob_3650	2.837e-220	702.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
YYD3_k127_2253419_2	313606.M23134_03754	9.528e-17	90.0	2DS14@1|root,33E1R@2|Bacteria,4NXJ9@976|Bacteroidetes,47SSF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
YYD3_k127_2253419_3	234267.Acid_5749	0.0007497	46.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2254940_5	1123508.JH636452_gene7055	6.341e-97	323.0	COG1028@1|root,COG1028@2|Bacteria	1123508.JH636452_gene7055|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2254940_3	1054213.HMPREF9946_04488	1.153e-102	351.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	algG	-	5.1.3.37	ko:K01795	ko00051,map00051	-	R08693	RC00509	ko00000,ko00001,ko01000	-	-	-	Beta_helix,DUF1565,NosD
YYD3_k127_2254940_11	313589.JNB_05545	2.309e-41	169.0	COG2227@1|root,COG2227@2|Bacteria,2GQYM@201174|Actinobacteria,4FI85@85021|Intrasporangiaceae	201174|Actinobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_2254940_6	1380355.JNIJ01000089_gene2468	1.707e-82	297.0	COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2V8VX@28211|Alphaproteobacteria,3K1ZD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2254940_19	376686.Fjoh_4177	1.283e-06	56.0	COG2273@1|root,COG2273@2|Bacteria,4NKMT@976|Bacteroidetes,1IJUZ@117743|Flavobacteriia,2NV1U@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
YYD3_k127_2254940_21	143224.JQMD01000002_gene3799	0.0004082	44.0	COG2133@1|root,COG2911@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,4PKJH@976|Bacteroidetes,1IJAY@117743|Flavobacteriia	976|Bacteroidetes	G	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PKD
YYD3_k127_2254940_13	1121926.AXWO01000001_gene3399	2.168e-34	141.0	COG2730@1|root,COG2730@2|Bacteria,2H7D7@201174|Actinobacteria,4F071@85014|Glycomycetales	201174|Actinobacteria	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,RicinB_lectin_2,Ricin_B_lectin
YYD3_k127_2254940_20	497964.CfE428DRAFT_0245	7.541e-05	53.0	COG3506@1|root,COG5434@1|root,COG3506@2|Bacteria,COG5434@2|Bacteria,46VT5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
YYD3_k127_2254940_17	1227739.Hsw_4191	1.035e-17	93.0	COG2133@1|root,COG2273@1|root,COG3325@1|root,COG2133@2|Bacteria,COG2273@2|Bacteria,COG3325@2|Bacteria,4NKMT@976|Bacteroidetes	976|Bacteroidetes	G	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
YYD3_k127_2254940_8	1173027.Mic7113_1165	9.219e-57	211.0	2925F@1|root,2ZPQC@2|Bacteria,1G6AN@1117|Cyanobacteria,1HBS5@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
YYD3_k127_2254940_16	1349767.GJA_2659	2.848e-21	105.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,474GQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
YYD3_k127_2254940_15	1347392.CCEZ01000018_gene1076	4.531e-29	126.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,36H48@31979|Clostridiaceae	186801|Clostridia	K	response regulator, receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_2254940_12	1340493.JNIF01000004_gene643	1.382e-36	148.0	COG1596@1|root,COG1596@2|Bacteria,3Y591@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YYD3_k127_2254940_14	926566.Terro_1728	9.613e-33	144.0	COG3206@1|root,COG3206@2|Bacteria,3Y4H3@57723|Acidobacteria,2JJ3W@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
YYD3_k127_2254940_18	247490.KSU1_C0002	5.559e-11	73.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2J0AY@203682|Planctomycetes	203682|Planctomycetes	D	Capsular exopolysaccharide family	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
YYD3_k127_2254940_4	1267535.KB906767_gene2401	1.043e-101	350.0	COG2148@1|root,COG2148@2|Bacteria,3Y3GZ@57723|Acidobacteria,2JIAU@204432|Acidobacteriia	204432|Acidobacteriia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YYD3_k127_2254940_0	525904.Tter_1172	3.916e-160	510.0	COG0451@1|root,COG0451@2|Bacteria,2NPS7@2323|unclassified Bacteria	2|Bacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD3_k127_2254940_2	604331.AUHY01000023_gene1652	7.207e-111	368.0	COG1922@1|root,COG1922@2|Bacteria,1WJJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
YYD3_k127_2254940_7	56110.Oscil6304_2655	2.38e-73	256.0	COG0500@1|root,COG2226@2|Bacteria,1GGSE@1117|Cyanobacteria,1HGM1@1150|Oscillatoriales	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_2254940_10	1123389.ATXJ01000021_gene1071	1.584e-48	188.0	COG0438@1|root,COG0438@2|Bacteria,1WK9I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_2254940_9	319795.Dgeo_2502	2.93e-56	216.0	COG2244@1|root,COG2244@2|Bacteria,1WKII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2254940_1	319795.Dgeo_2505	2.011e-126	415.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_2259145_1	1121920.AUAU01000006_gene330	6.713e-52	210.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_2259145_0	290397.Adeh_2899	5.711e-109	385.0	COG0823@1|root,COG0823@2|Bacteria,1NKG5@1224|Proteobacteria	1224|Proteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD3_k127_2259145_3	1267534.KB906757_gene1063	2.373e-05	52.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_2269068_5	290397.Adeh_4303	2.661e-51	195.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD3_k127_2269068_3	886293.Sinac_0691	4.861e-98	337.0	2ET0U@1|root,33KJ2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2269068_0	639030.JHVA01000001_gene841	5.616e-218	705.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
YYD3_k127_2269068_8	706587.Desti_2926	5.474e-20	92.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42WGE@68525|delta/epsilon subdivisions,2WRF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YYD3_k127_2269068_2	1379270.AUXF01000001_gene2562	2.826e-111	372.0	COG0513@1|root,COG0513@2|Bacteria,1ZSX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JKL	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YYD3_k127_2269068_7	1192034.CAP_7104	2.645e-28	124.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1PQD2@1224|Proteobacteria,4323R@68525|delta/epsilon subdivisions,2WXJB@28221|Deltaproteobacteria,2Z10C@29|Myxococcales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_1,TPR_17,TPR_8
YYD3_k127_2269068_4	443144.GM21_2219	1.2e-69	247.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,42QTP@68525|delta/epsilon subdivisions,2WN6N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
YYD3_k127_2269068_1	335659.S23_39120	5.544e-145	475.0	COG0277@1|root,COG0277@2|Bacteria,1QA8T@1224|Proteobacteria,2UZ74@28211|Alphaproteobacteria,3K5MN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
YYD3_k127_2269068_6	1340493.JNIF01000003_gene2123	1.587e-33	141.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2312039_5	1122239.AULS01000004_gene1338	0.0004809	47.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_2312039_3	1385520.N802_07710	2.554e-09	60.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_2312039_1	234267.Acid_5749	5.734e-209	679.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2312039_0	234267.Acid_3725	8.41e-223	719.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2312039_4	1382356.JQMP01000003_gene1357	5.819e-07	55.0	COG1977@1|root,COG1977@2|Bacteria,2GBBB@200795|Chloroflexi,27Z8W@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD3_k127_2312039_2	443143.GM18_0358	1.842e-73	253.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
YYD3_k127_2313301_0	663610.JQKO01000012_gene3076	3.176e-72	254.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2313301_1	247633.GP2143_17796	2.239e-39	159.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2313301_2	1047013.AQSP01000100_gene599	4.325e-36	159.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_231654_5	1220534.B655_0937	7.461e-05	51.0	arCOG01917@1|root,arCOG01917@2157|Archaea	2157|Archaea	M	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3,zinc_ribbon_2
YYD3_k127_231654_3	290397.Adeh_2010	7.685e-32	133.0	COG1913@1|root,COG1913@2|Bacteria,1NEU5@1224|Proteobacteria,42WCP@68525|delta/epsilon subdivisions,2X5BA@28221|Deltaproteobacteria,2Z2ND@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
YYD3_k127_231654_0	290397.Adeh_2009	3.748e-194	614.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
YYD3_k127_231654_2	290397.Adeh_2007	1.154e-103	345.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2Z1ZF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
YYD3_k127_231654_1	290397.Adeh_2006	1.033e-134	438.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
YYD3_k127_2316670_16	1267533.KB906735_gene4737	1.938e-09	59.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2316670_15	710111.FraQA3DRAFT_1200	1.094e-09	70.0	COG0500@1|root,COG2226@2|Bacteria,2I3AK@201174|Actinobacteria,4EXCB@85013|Frankiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_2316670_7	351160.RCIX1920	3.254e-67	236.0	COG0110@1|root,arCOG01848@2157|Archaea,2XWJM@28890|Euryarchaeota,2N98J@224756|Methanomicrobia	224756|Methanomicrobia	S	transferase hexapeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
YYD3_k127_2316670_6	1430440.MGMSRv2_3402	6.201e-85	293.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,2JSRW@204441|Rhodospirillales	204441|Rhodospirillales	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_2316670_12	1121406.JAEX01000017_gene1945	2.402e-31	136.0	COG0451@1|root,COG0451@2|Bacteria,1RKD3@1224|Proteobacteria,42U2S@68525|delta/epsilon subdivisions,2WVN0@28221|Deltaproteobacteria,2MD58@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD3_k127_2316670_11	309801.trd_0619	4.54e-34	143.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_2316670_14	5722.XP_001581386.1	3.717e-17	93.0	2E3SF@1|root,2SAST@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2316670_9	234267.Acid_0623	1e-52	209.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding,TPR_8
YYD3_k127_2316670_4	234267.Acid_0558	2.442e-119	392.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
YYD3_k127_2316670_3	234267.Acid_0622	6.061e-145	473.0	COG1004@1|root,COG1004@2|Bacteria,3Y3GR@57723|Acidobacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD3_k127_2316670_2	1205680.CAKO01000003_gene3681	1.074e-151	485.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
YYD3_k127_2316670_17	1051632.TPY_1415	8.362e-09	69.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8,Pro-kuma_activ
YYD3_k127_2316670_18	345341.KUTG_00136	1.756e-07	64.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4DYCY@85010|Pseudonocardiales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Ricin_B_lectin
YYD3_k127_2316670_10	330214.NIDE0518	6.576e-35	141.0	COG2802@1|root,COG2802@2|Bacteria,3J13Q@40117|Nitrospirae	40117|Nitrospirae	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
YYD3_k127_2316670_1	1382359.JIAL01000001_gene2487	1.332e-157	509.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria,2JHSR@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
YYD3_k127_2316670_0	1267535.KB906767_gene4009	6.112e-184	587.0	COG1239@1|root,COG1239@2|Bacteria,3Y3FM@57723|Acidobacteria,2JHY2@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
YYD3_k127_2316670_8	399739.Pmen_0662	1.317e-57	210.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,1S3SX@1236|Gammaproteobacteria,1YHMZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
YYD3_k127_2316670_5	670487.Ocepr_0388	5.927e-86	295.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_2335660_1	713586.KB900536_gene2253	1.72e-69	244.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,1WZJX@135613|Chromatiales	135613|Chromatiales	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
YYD3_k127_2335660_0	370438.PTH_0039	5.786e-115	384.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_2335660_2	326427.Cagg_0009	1.096e-38	147.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi,376XE@32061|Chloroflexia	32061|Chloroflexia	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_2338475_2	1122222.AXWR01000033_gene2219	3.835e-17	82.0	COG0251@1|root,COG0251@2|Bacteria,1WK0P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YYD3_k127_2338475_0	1267533.KB906741_gene424	6.786e-248	784.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YYD3_k127_2338475_3	41431.PCC8801_1300	1.536e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,1GIT8@1117|Cyanobacteria,3KHZU@43988|Cyanothece	1117|Cyanobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8,Trypsin_2
YYD3_k127_2338475_1	1379270.AUXF01000001_gene2815	5.025e-168	547.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_2339492_10	290397.Adeh_1326	3.148e-54	197.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2339492_7	404380.Gbem_0470	5.715e-81	280.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD3_k127_2339492_2	1235279.C772_00547	1.951e-137	450.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,26EMG@186818|Planococcaceae	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
YYD3_k127_2339492_1	497965.Cyan7822_0107	6.893e-249	797.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1G092@1117|Cyanobacteria,3KGR1@43988|Cyanothece	1117|Cyanobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
YYD3_k127_2339492_9	1121472.AQWN01000001_gene111	6.47e-69	248.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
YYD3_k127_2339492_18	1082931.KKY_3160	5.371e-18	88.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,3N72P@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
YYD3_k127_2339492_13	278963.ATWD01000001_gene2512	2.936e-32	126.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YYD3_k127_2339492_3	1123376.AUIU01000016_gene303	4.61e-117	387.0	COG0536@1|root,COG0536@2|Bacteria,3J0E3@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
YYD3_k127_2339492_12	292459.STH434	3.774e-38	152.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD3_k127_2339492_16	204669.Acid345_0022	1.452e-27	117.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria,2JJ9Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
YYD3_k127_2339492_15	78245.Xaut_3090	6.166e-31	132.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,3EZ7T@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YYD3_k127_2339492_5	518766.Rmar_1907	1.019e-107	370.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YYD3_k127_2339492_14	221103.XP_007850782.1	5.453e-31	129.0	COG0125@1|root,KOG3327@2759|Eukaryota,39U2H@33154|Opisthokonta,3P2YY@4751|Fungi,3V0X5@5204|Basidiomycota,228D0@155619|Agaricomycetes,3W6WV@5338|Agaricales	4751|Fungi	F	thymidylate kinase	CDC8	GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YYD3_k127_2339492_4	1380394.JADL01000003_gene5194	1.646e-110	371.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,2JPEE@204441|Rhodospirillales	204441|Rhodospirillales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD3_k127_2339492_11	204669.Acid345_1027	3.757e-43	166.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria,2JJAJ@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2339492_19	234267.Acid_0107	1.122e-10	70.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_2339492_20	204669.Acid345_3665	1.168e-06	59.0	2DJMQ@1|root,32UDD@2|Bacteria,3Y57W@57723|Acidobacteria,2JJP8@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2339492_8	272558.10176317	1.743e-72	262.0	COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus	91061|Bacilli	P	Protein of unknown function (DUF418)	yrkO	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
YYD3_k127_2339492_6	1452718.JBOY01000066_gene2404	6.337e-84	287.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
YYD3_k127_2339492_0	338963.Pcar_0087	0.0	1119.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,43SBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ABC transporter	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YYD3_k127_2351058_1	1123242.JH636434_gene4003	1.672e-130	433.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
YYD3_k127_2351058_6	234267.Acid_2431	2.251e-80	278.0	2F63Z@1|root,33YN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2351058_4	1123508.JH636442_gene4015	7.968e-102	347.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_2351058_9	1403819.BATR01000066_gene1961	1.036e-39	157.0	COG4785@1|root,COG4785@2|Bacteria,46WU1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	May be involved in cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2351058_10	395019.Bmul_3791	4.649e-08	61.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2VTJR@28216|Betaproteobacteria,1K8AF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_2351058_2	344747.PM8797T_05400	5.228e-127	418.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_2351058_7	234267.Acid_4468	3.163e-64	229.0	2CDZB@1|root,2ZBFS@2|Bacteria,3Y5HH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2351058_3	1382359.JIAL01000001_gene110	3.446e-117	395.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria,2JHUM@204432|Acidobacteriia	204432|Acidobacteriia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
YYD3_k127_2351058_5	1047013.AQSP01000140_gene2461	1.757e-85	297.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
YYD3_k127_2351058_11	314260.PB2503_07379	3.312e-05	56.0	COG3595@1|root,COG3595@2|Bacteria,1QUNK@1224|Proteobacteria,2TW1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2351058_0	1089550.ATTH01000001_gene794	2.741e-265	832.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1FIMS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD3_k127_2351058_8	518766.Rmar_1803	2.454e-43	169.0	COG0287@1|root,COG4747@1|root,COG0287@2|Bacteria,COG4747@2|Bacteria,4NEKF@976|Bacteroidetes,1FJ4K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YYD3_k127_235769_0	1117647.M5M_17220	6.973e-131	430.0	COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,1JA4W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YYD3_k127_235769_3	980584.AFPB01000174_gene1596	7.129e-23	104.0	COG0399@1|root,COG0399@2|Bacteria,4P9JE@976|Bacteroidetes,1IGJK@117743|Flavobacteriia,4078G@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YYD3_k127_235769_1	234267.Acid_3334	1.504e-73	261.0	COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
YYD3_k127_235769_4	926560.KE387025_gene4038	3.584e-08	60.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1WI35@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,Dehyd-heme_bind
YYD3_k127_235769_2	1128421.JAGA01000002_gene1518	8.46e-31	122.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
YYD3_k127_2373825_2	234267.Acid_3357	2.315e-05	47.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_2373825_1	1230476.C207_03224	7.353e-08	64.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3JTTQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2373825_0	234267.Acid_6167	2.595e-15	83.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	nreC3	-	-	-	-	-	-	-	-	-	-	-	GerE
YYD3_k127_2374944_2	639030.JHVA01000001_gene1884	4.831e-29	130.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2374944_1	1120972.AUMH01000006_gene1809	1.09e-44	175.0	COG0657@1|root,COG0657@2|Bacteria,1UWRG@1239|Firmicutes,4I9QW@91061|Bacilli,27AB6@186823|Alicyclobacillaceae	91061|Bacilli	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YYD3_k127_2374944_0	1340493.JNIF01000003_gene1816	1.886e-133	432.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	He_PIG,NHL,SGL
YYD3_k127_2381528_1	768671.ThimaDRAFT_3012	2.472e-36	149.0	2C8KX@1|root,32RMF@2|Bacteria,1N68G@1224|Proteobacteria,1SDSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
YYD3_k127_2381528_0	1121015.N789_03455	5.086e-51	192.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XCG4@135614|Xanthomonadales	135614|Xanthomonadales	D	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
YYD3_k127_2384789_5	1502852.FG94_02296	1.328e-35	140.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,474DH@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YYD3_k127_2384789_2	1267533.KB906738_gene2234	8.379e-134	458.0	COG2844@1|root,COG2844@2|Bacteria,3Y2FJ@57723|Acidobacteria,2JI19@204432|Acidobacteriia	204432|Acidobacteriia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
YYD3_k127_2384789_7	1396141.BATP01000028_gene2319	0.0001027	53.0	2EU5N@1|root,32KSV@2|Bacteria,46X68@74201|Verrucomicrobia,2IUN0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2384789_6	1403819.BATR01000105_gene3638	5.1e-17	91.0	2EU5N@1|root,33MN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2384789_1	262724.TT_C1950	8.297e-178	565.0	COG0004@1|root,COG0004@2|Bacteria,1WIFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
YYD3_k127_2384789_0	1267534.KB906757_gene1155	7.157e-222	709.0	COG0480@1|root,COG0480@2|Bacteria,3Y2RR@57723|Acidobacteria,2JI85@204432|Acidobacteriia	204432|Acidobacteriia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_2384789_4	1382303.JPOM01000001_gene1832	7.223e-36	143.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2KGBZ@204458|Caulobacterales	204458|Caulobacterales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YYD3_k127_2384789_3	1267533.KB906735_gene5103	4.9e-103	340.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YYD3_k127_2409569_22	1045855.DSC_15185	1.657e-21	100.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
YYD3_k127_2409569_4	237368.SCABRO_03072	1.192e-85	292.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	cmoA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	2.8.1.10	ko:K03149,ko:K15256	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
YYD3_k127_2409569_10	234267.Acid_2512	2.286e-49	183.0	COG1595@1|root,COG1595@2|Bacteria,3Y8V2@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2409569_17	234267.Acid_6900	5.221e-36	148.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
YYD3_k127_2409569_7	690850.Desaf_0971	8.887e-59	216.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2409569_8	234267.Acid_1603	6.322e-52	196.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria	57723|Acidobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_2409569_18	1123508.JH636456_gene134	4.951e-35	145.0	COG2202@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3,STAS
YYD3_k127_2409569_13	667632.KB890164_gene2209	2.517e-44	168.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria	1224|Proteobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K05518	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
YYD3_k127_2409569_11	667632.KB890164_gene2210	1.914e-46	173.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,2VSW8@28216|Betaproteobacteria,1K88Q@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
YYD3_k127_2409569_14	667632.KB890164_gene2211	2.835e-44	165.0	COG1366@1|root,COG1366@2|Bacteria,1RJM8@1224|Proteobacteria,2VT28@28216|Betaproteobacteria,1K7XA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_2409569_1	469383.Cwoe_3437	4.68e-133	430.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
YYD3_k127_2409569_25	1419583.V466_30385	5.956e-07	57.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2409569_9	318424.EU78_23200	1.037e-50	187.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,2371P@1762|Mycobacteriaceae	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
YYD3_k127_2409569_3	570967.JMLV01000008_gene1306	2.734e-91	316.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2JPVS@204441|Rhodospirillales	204441|Rhodospirillales	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
YYD3_k127_2409569_15	243231.GSU0287	7.62e-44	178.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PHB@68525|delta/epsilon subdivisions,2WMJX@28221|Deltaproteobacteria,43S0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,KOW
YYD3_k127_2409569_6	1380394.JADL01000010_gene4296	1.144e-60	222.0	COG3386@1|root,COG3386@2|Bacteria,1RHPS@1224|Proteobacteria,2UBD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2409569_16	1267535.KB906767_gene227	3.186e-36	146.0	COG1881@1|root,COG1881@2|Bacteria,3Y5UH@57723|Acidobacteria,2JNWC@204432|Acidobacteriia	204432|Acidobacteriia	S	Phosphatidylethanolamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP
YYD3_k127_2409569_12	1198452.Jab_1c17810	2.812e-46	181.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VK61@28216|Betaproteobacteria,47775@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	gnl1	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
YYD3_k127_2409569_20	1094715.CM001373_gene663	4.588e-26	117.0	2AH6M@1|root,317GF@2|Bacteria,1RKMX@1224|Proteobacteria,1SUSB@1236|Gammaproteobacteria,1JFK2@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2409569_5	583345.Mmol_0846	3.056e-85	294.0	2C55T@1|root,2ZARV@2|Bacteria,1R77G@1224|Proteobacteria,2VSED@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
YYD3_k127_2409569_2	1038859.AXAU01000016_gene6832	6.633e-119	389.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3JRVC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_2409569_27	1340493.JNIF01000003_gene4475	8.37e-06	55.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_2409569_24	504472.Slin_2516	9.635e-08	63.0	COG0346@1|root,COG0346@2|Bacteria,4NHD0@976|Bacteroidetes,47U3G@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_2409569_26	875328.JDM601_3263	9.381e-07	53.0	COG1848@1|root,COG1848@2|Bacteria,2IK8U@201174|Actinobacteria,2396G@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_2409569_0	1266925.JHVX01000013_gene1654	4.578e-301	934.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,372VA@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
YYD3_k127_2409569_21	388413.ALPR1_15839	6.351e-22	106.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,47V7E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2426348_0	234267.Acid_5375	5.955e-65	235.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2426348_2	641491.DND132_2495	5.042e-26	116.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,42TS3@68525|delta/epsilon subdivisions,2WQN1@28221|Deltaproteobacteria,2MCJM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
YYD3_k127_2426348_3	317936.Nos7107_0339	7.207e-25	108.0	2CIIF@1|root,315FB@2|Bacteria,1G6R8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2491770_0	234267.Acid_4415	5.041e-63	224.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD3_k127_2491770_1	234267.Acid_3898	1.423e-41	172.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
YYD3_k127_2496970_2	196490.AUEZ01000002_gene4240	6.29e-185	586.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2U0D0@28211|Alphaproteobacteria,3JURI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
YYD3_k127_2496970_0	338966.Ppro_0419	3.036e-305	949.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,43U1C@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YYD3_k127_2496970_1	768671.ThimaDRAFT_4559	4.807e-216	685.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXWA@135613|Chromatiales	135613|Chromatiales	U	sulphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
YYD3_k127_2496970_3	401053.AciPR4_2597	6.524e-184	607.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria,2JKKF@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_2511304_1	1163409.UUA_18294	8.88e-13	70.0	COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,1T2EV@1236|Gammaproteobacteria,1XD5B@135614|Xanthomonadales	135614|Xanthomonadales	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
YYD3_k127_2511304_3	411154.GFO_0980	0.0003402	51.0	COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2511304_2	35754.JNYJ01000042_gene1357	8.532e-11	73.0	COG3391@1|root,COG3391@2|Bacteria,2HWNH@201174|Actinobacteria,4DJP0@85008|Micromonosporales	201174|Actinobacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
YYD3_k127_2511304_0	234267.Acid_5749	5.736e-110	381.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2539942_1	1444711.CCJF01000005_gene918	5.395e-25	112.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD3_k127_2539942_0	321327.CYA_1531	2.417e-46	183.0	COG0739@1|root,COG0739@2|Bacteria,1GGCW@1117|Cyanobacteria,1H2H9@1129|Synechococcus	1117|Cyanobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD3_k127_2553409_0	627192.SLG_04410	1.751e-119	417.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K1V6@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_2553409_1	234267.Acid_3938	9.956e-94	327.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2553409_3	401053.AciPR4_0047	2.702e-06	50.0	COG0577@1|root,COG0577@2|Bacteria,3Y410@57723|Acidobacteria,2JNZI@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2553409_2	555793.WSK_4047	3.253e-19	94.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2590454_0	1502851.FG93_00182	4.538e-135	450.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
YYD3_k127_2597053_0	398512.JQKC01000010_gene60	2.925e-64	229.0	COG3291@1|root,COG5337@1|root,COG3291@2|Bacteria,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes	1239|Firmicutes	M	Spore Coat Protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,PKD
YYD3_k127_2597053_1	1123354.AUDR01000020_gene1992	8.423e-36	143.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1KRJZ@119069|Hydrogenophilales	119069|Hydrogenophilales	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2597134_5	1519464.HY22_08585	4.938e-112	380.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
YYD3_k127_2597134_26	443143.GM18_3269	1.572e-09	68.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria,42X7Z@68525|delta/epsilon subdivisions,2WSMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
YYD3_k127_2597134_18	357808.RoseRS_2131	3.049e-28	119.0	COG2062@1|root,COG2062@2|Bacteria,2GB93@200795|Chloroflexi,377KE@32061|Chloroflexia	32061|Chloroflexia	T	TIGRFAM phosphohistidine phosphatase SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
YYD3_k127_2597134_17	331113.SNE_A07170	2.254e-50	190.0	COG1597@1|root,COG1597@2|Bacteria,2JH3J@204428|Chlamydiae	204428|Chlamydiae	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YYD3_k127_2597134_15	350688.Clos_1392	5.656e-54	199.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_2597134_0	234267.Acid_7271	5.977e-261	827.0	COG0421@1|root,COG0421@2|Bacteria,3Y6UP@57723|Acidobacteria	57723|Acidobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YYD3_k127_2597134_3	402777.KB235904_gene4517	4.788e-129	424.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria,1H7C1@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
YYD3_k127_2597134_1	1267533.KB906738_gene2315	4.079e-239	745.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
YYD3_k127_2597134_13	1267533.KB906738_gene2316	1.358e-59	213.0	2AI77@1|root,318MJ@2|Bacteria,3Y7RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2597134_27	926569.ANT_06410	1.114e-08	68.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
YYD3_k127_2597134_21	1112212.JH584235_gene2729	3.645e-20	91.0	COG1278@1|root,COG1278@2|Bacteria,1QRMX@1224|Proteobacteria,2V17U@28211|Alphaproteobacteria,2KB7U@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock protein domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
YYD3_k127_2597134_11	1340493.JNIF01000003_gene4369	3.601e-71	251.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119	GDPD
YYD3_k127_2597134_9	1232410.KI421426_gene1377	7.92e-72	246.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,42MQB@68525|delta/epsilon subdivisions,2WPIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YYD3_k127_2597134_20	1227739.Hsw_3268	1.061e-25	124.0	COG5617@1|root,COG5617@2|Bacteria,4P1FA@976|Bacteroidetes,47UGP@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2597134_14	1242864.D187_001222	6.399e-56	198.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YYD3_k127_2597134_19	266117.Rxyl_2877	5.258e-28	118.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
YYD3_k127_2597134_2	1192034.CAP_4280	1.07e-139	479.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions,2X77J@28221|Deltaproteobacteria,2YUN6@29|Myxococcales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_2597134_10	1227739.Hsw_3750	8.77e-72	265.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,47MBP@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
YYD3_k127_2597134_24	517418.Ctha_1739	2.281e-14	79.0	2ES4T@1|root,33JPM@2|Bacteria,1FFC2@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2597134_6	398767.Glov_0589	4.965e-99	345.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
YYD3_k127_2597134_12	443143.GM18_1481	7.846e-67	234.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,43TEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_2597134_4	234267.Acid_3186	2.076e-117	387.0	COG0306@1|root,COG0306@2|Bacteria,3Y3ZW@57723|Acidobacteria	57723|Acidobacteria	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
YYD3_k127_2597134_16	243231.GSU0388	1.186e-51	190.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
YYD3_k127_2597134_22	425104.Ssed_1027	3.325e-17	91.0	COG0671@1|root,COG0671@2|Bacteria,1N034@1224|Proteobacteria,1S9KY@1236|Gammaproteobacteria,2QB0R@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD3_k127_2597134_7	309807.SRU_0977	5.391e-79	285.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2597134_25	1408433.JHXV01000001_gene956	9.709e-11	74.0	COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,1HZTM@117743|Flavobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD3_k127_2597134_8	1089550.ATTH01000001_gene1890	3.197e-75	275.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2625960_4	234267.Acid_2901	1.514e-62	225.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
YYD3_k127_2625960_5	243231.GSU0031	1.235e-56	213.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
YYD3_k127_2625960_6	1122917.KB899659_gene5596	7.054e-39	151.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YYD3_k127_2625960_2	1232410.KI421424_gene1723	2.705e-129	428.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD3_k127_2625960_7	994573.T472_0213105	7.595e-33	138.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,36FBU@31979|Clostridiaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YYD3_k127_2625960_3	1379270.AUXF01000007_gene963	1.927e-65	244.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
YYD3_k127_2625960_0	234267.Acid_0368	1.321e-190	601.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YYD3_k127_2625960_1	1286093.C266_24388	6.235e-138	453.0	COG0654@1|root,COG0654@2|Bacteria,1R0KI@1224|Proteobacteria,2WIEI@28216|Betaproteobacteria	28216|Betaproteobacteria	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
YYD3_k127_2627920_0	1163617.SCD_n02239	5.939e-129	417.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
YYD3_k127_2627920_1	215803.DB30_5797	3.007e-98	338.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,438ST@68525|delta/epsilon subdivisions,2X9CS@28221|Deltaproteobacteria,2YXPE@29|Myxococcales	28221|Deltaproteobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2627920_3	103733.JNYO01000026_gene8831	4.089e-05	51.0	COG3541@1|root,COG3541@2|Bacteria,2GUQV@201174|Actinobacteria,4E3CD@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
YYD3_k127_2627920_2	1122970.AUHC01000021_gene2458	2.549e-77	267.0	COG3794@1|root,COG3794@2|Bacteria,1R29B@1224|Proteobacteria	1224|Proteobacteria	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
YYD3_k127_2636907_0	359.CN09_26010	1.756e-132	430.0	COG0657@1|root,COG0657@2|Bacteria,1R41U@1224|Proteobacteria,2U17T@28211|Alphaproteobacteria,4BIBG@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YYD3_k127_2636907_1	215803.DB30_5408	6.166e-55	202.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42TDM@68525|delta/epsilon subdivisions,2WP8D@28221|Deltaproteobacteria,2YV8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
YYD3_k127_2651871_1	159087.Daro_3427	1.111e-96	332.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YYD3_k127_2651871_0	234267.Acid_4577	3.405e-208	660.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_26594_1	1379698.RBG1_1C00001G0669	5.207e-49	184.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	Peptidase_M56
YYD3_k127_26594_0	1267535.KB906767_gene4753	1.001e-188	605.0	COG0419@1|root,COG0515@1|root,COG0419@2|Bacteria,COG0515@2|Bacteria	2|Bacteria	KLT	protein kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	AAA_15,AAA_21,DUF4339,TMP_2,Tubulin_2
YYD3_k127_2681407_5	479434.Sthe_1793	2.962e-38	146.0	COG1804@1|root,COG1804@2|Bacteria,2G61Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
YYD3_k127_2681407_2	1121106.JQKB01000104_gene5603	4.437e-81	279.0	COG1028@1|root,COG1028@2|Bacteria,1R4V3@1224|Proteobacteria,2U2KY@28211|Alphaproteobacteria,2JW3E@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD3_k127_2681407_3	1118054.CAGW01000056_gene2111	6.284e-80	269.0	COG2030@1|root,COG2030@2|Bacteria,1V3VC@1239|Firmicutes,4HH24@91061|Bacilli	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
YYD3_k127_2681407_1	246194.CHY_0061	1.273e-87	301.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,42EX5@68295|Thermoanaerobacterales	186801|Clostridia	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
YYD3_k127_2681407_4	1121445.ATUZ01000001_gene153	2.226e-45	173.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria,2MGV1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
YYD3_k127_2681407_6	1340493.JNIF01000003_gene2123	2.549e-35	145.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2681407_8	1282360.ABAC460_08205	7.042e-12	70.0	COG4118@1|root,COG4118@2|Bacteria,1NME9@1224|Proteobacteria,2UMMS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YYD3_k127_2681407_7	102125.Xen7305DRAFT_00002310	1.23e-17	87.0	COG3744@1|root,COG3744@2|Bacteria,1G5SF@1117|Cyanobacteria,3VNBS@52604|Pleurocapsales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_2681407_0	1207063.P24_13101	2.268e-109	359.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2TRG9@28211|Alphaproteobacteria,2JQV5@204441|Rhodospirillales	204441|Rhodospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2681407_9	1267535.KB906767_gene687	1.739e-09	63.0	COG0477@1|root,COG2814@2|Bacteria,3Y2RQ@57723|Acidobacteria,2JHZK@204432|Acidobacteriia	204432|Acidobacteriia	EGP	PFAM Major facilitator superfamily	-	-	-	ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12	-	-	MFS_1,Sugar_tr
YYD3_k127_2697738_6	1380355.JNIJ01000009_gene1657	6.155e-14	73.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria,3JRKI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	2.2.1.6,4.1.1.8	ko:K01577,ko:K01652	ko00290,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01908,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00620,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD3_k127_2697738_1	861299.J421_0962	3.445e-91	326.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
YYD3_k127_2697738_4	105425.BBPL01000004_gene7770	8.328e-56	205.0	COG4122@1|root,COG4122@2|Bacteria,2IR7F@201174|Actinobacteria,2NMD2@228398|Streptacidiphilus	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YYD3_k127_2697738_2	667632.KB890164_gene2157	3.191e-87	297.0	COG4977@1|root,COG4977@2|Bacteria,1QZQE@1224|Proteobacteria,2WHN5@28216|Betaproteobacteria,1KIP6@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YYD3_k127_2697738_3	1267535.KB906767_gene4863	4.202e-63	226.0	COG3554@1|root,COG3554@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
YYD3_k127_2697738_7	526227.Mesil_1708	2.025e-08	62.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_2697738_0	357808.RoseRS_1363	4.254e-180	594.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
YYD3_k127_2697738_5	1123499.KB908028_gene102	1.492e-21	108.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VP3I@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_2708933_2	1040989.AWZU01000004_gene7078	2.533e-263	814.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria,3JRKI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	2.2.1.6,4.1.1.8	ko:K01577,ko:K01652	ko00290,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01908,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00620,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD3_k127_2708933_3	1380394.JADL01000005_gene5613	1.215e-243	755.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TTM5@28211|Alphaproteobacteria,2JVI4@204441|Rhodospirillales	204441|Rhodospirillales	C	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate	frc	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
YYD3_k127_2708933_0	1411123.JQNH01000001_gene2121	0.0	1186.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TQYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	MA20_15065	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
YYD3_k127_2708933_1	316067.Geob_2478	0.0	1123.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YYD3_k127_2708933_14	1206744.BAGL01000027_gene7464	0.0001622	51.0	290TB@1|root,31J2J@2|Bacteria,2INHR@201174|Actinobacteria,4G3KE@85025|Nocardiaceae	201174|Actinobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
YYD3_k127_2708933_12	517722.AEUE01000010_gene539	3.433e-07	63.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,2K36Q@204457|Sphingomonadales	204457|Sphingomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD3_k127_2708933_9	316067.Geob_0857	1.973e-40	168.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
YYD3_k127_2708933_7	1458357.BG58_31930	1.402e-112	375.0	COG0169@1|root,COG0169@2|Bacteria,1MVW5@1224|Proteobacteria,2VJU3@28216|Betaproteobacteria,1K4DF@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Shikimate dehydrogenase substrate binding domain	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N,ThiF
YYD3_k127_2708933_5	748247.AZKH_p0479	3.978e-218	684.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,2KW0D@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YYD3_k127_2708933_4	1177594.MIC448_1100038	2.505e-234	736.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FM3X@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD3_k127_2708933_6	113395.AXAI01000016_gene4943	3.549e-192	618.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JS0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	repeat protein	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2708933_8	234267.Acid_5050	6.484e-58	218.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M,NPCBM,Peptidase_M16,Peptidase_M16_C
YYD3_k127_2708933_10	663610.JQKO01000012_gene3165	1.278e-32	138.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YYD3_k127_2708933_13	304371.MCP_0028	2.216e-05	53.0	COG0346@1|root,arCOG02708@2157|Archaea,2Y1HZ@28890|Euryarchaeota	28890|Euryarchaeota	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_2727343_2	29581.BW37_00998	1.018e-13	74.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2VRM6@28216|Betaproteobacteria,474SR@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
YYD3_k127_2727343_1	861299.J421_1368	4.967e-126	418.0	COG0312@1|root,COG0312@2|Bacteria,1ZSYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
YYD3_k127_2727343_0	861299.J421_1204	1.681e-158	515.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD3_k127_2756074_3	1047013.AQSP01000066_gene718	7.925e-38	165.0	COG3419@1|root,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
YYD3_k127_2756074_4	290397.Adeh_1301	6.791e-05	54.0	COG3063@1|root,COG3063@2|Bacteria,1RK88@1224|Proteobacteria,42SIP@68525|delta/epsilon subdivisions,2WPT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	TPR repeat	tgl	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
YYD3_k127_2756074_5	1121405.dsmv_2165	0.0005172	52.0	COG4966@1|root,COG4966@2|Bacteria,1QXTT@1224|Proteobacteria,42V8D@68525|delta/epsilon subdivisions,2WRP7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
YYD3_k127_2756074_2	1218086.BBNB01000012_gene1370	1.137e-43	177.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,1T26Z@1236|Gammaproteobacteria,3WX9B@544|Citrobacter	1236|Gammaproteobacteria	T	PAS fold	atoS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
YYD3_k127_2756074_0	243231.GSU2043	7.639e-66	234.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YYD3_k127_2756074_1	204669.Acid345_1573	6.686e-44	169.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2771328_3	1111728.ATYS01000013_gene4820	1.335e-25	111.0	2ECK8@1|root,31WSQ@2|Bacteria,1RHU3@1224|Proteobacteria,1S8BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2771328_0	234267.Acid_5494	1.704e-118	388.0	COG3622@1|root,COG3622@2|Bacteria,3Y6XP@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YYD3_k127_2771328_1	1122135.KB893134_gene3318	4.552e-45	169.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
YYD3_k127_2771328_2	1121861.KB899918_gene3209	1.673e-28	121.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JQA8@204441|Rhodospirillales	204441|Rhodospirillales	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
YYD3_k127_2784603_16	1173028.ANKO01000115_gene5831	7.102e-39	153.0	COG2971@1|root,COG2971@2|Bacteria,1G3SA@1117|Cyanobacteria,1H9RT@1150|Oscillatoriales	1117|Cyanobacteria	G	BadF BadG BcrA BcrD	-	-	2.7.1.59	ko:K00884,ko:K02616	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	BcrAD_BadFG
YYD3_k127_2784603_10	1297742.A176_05915	3.006e-65	230.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,42NH0@68525|delta/epsilon subdivisions,2WM42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
YYD3_k127_2784603_8	518766.Rmar_2753	3.663e-77	270.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1FIKZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
YYD3_k127_2784603_5	292459.STH1821	2.751e-87	297.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD3_k127_2784603_18	1242864.D187_004771	1.621e-34	152.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
YYD3_k127_2784603_4	1047013.AQSP01000132_gene1731	2.879e-108	379.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	-	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
YYD3_k127_2784603_0	1267535.KB906767_gene4360	8.752e-163	538.0	COG1449@1|root,COG1449@2|Bacteria,3Y36M@57723|Acidobacteria,2JM7G@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
YYD3_k127_2784603_11	1047013.AQSP01000134_gene1379	2.675e-59	216.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD3_k127_2784603_7	1047013.AQSP01000134_gene1378	6.188e-82	280.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YYD3_k127_2784603_12	1499967.BAYZ01000157_gene585	1.311e-55	199.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
YYD3_k127_2784603_3	697281.Mahau_1931	5.036e-111	374.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,42FC8@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YYD3_k127_2784603_2	243231.GSU2064	1.705e-121	410.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
YYD3_k127_2784603_13	1121920.AUAU01000023_gene2424	5.731e-54	199.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
YYD3_k127_2784603_20	1125863.JAFN01000001_gene1509	5.946e-22	101.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
YYD3_k127_2784603_23	1267535.KB906767_gene3035	4.235e-05	54.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
YYD3_k127_2784603_9	1047013.AQSP01000135_gene1613	7.473e-68	249.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
YYD3_k127_2784603_19	1047013.AQSP01000135_gene1612	3.721e-34	141.0	COG2885@1|root,COG2885@2|Bacteria,2NPMV@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD3_k127_2784603_22	637390.AFOH01000111_gene2828	1.241e-06	60.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,2NCEN@225057|Acidithiobacillales	225057|Acidithiobacillales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6
YYD3_k127_2784603_14	215803.DB30_3249	1.15e-44	166.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YYD3_k127_2784603_15	1144275.COCOR_04539	3.395e-43	160.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_2784603_1	555079.Toce_1427	7.907e-123	414.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YYD3_k127_2784603_21	1123257.AUFV01000005_gene1375	6.219e-22	98.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1X7PU@135614|Xanthomonadales	135614|Xanthomonadales	G	phosphocarrier protein HPr	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
YYD3_k127_2784603_17	394221.Mmar10_0076	8.667e-35	137.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,43XZ4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	manX	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
YYD3_k127_2784603_6	240015.ACP_0619	1.34e-82	282.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
YYD3_k127_2786150_0	1210884.HG799462_gene8941	1.287e-226	713.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
YYD3_k127_2786150_1	344747.PM8797T_23786	8.481e-186	589.0	COG0174@1|root,COG0174@2|Bacteria,2IXHM@203682|Planctomycetes	203682|Planctomycetes	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YYD3_k127_2792285_0	234267.Acid_2226	1.763e-205	657.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YYD3_k127_2792285_1	479434.Sthe_1400	3.547e-76	265.0	COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi,27XP9@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
YYD3_k127_2792285_3	1177181.T9A_01260	1.357e-18	87.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1XJGS@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YYD3_k127_2792285_2	519989.ECTPHS_13927	2.841e-43	169.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YYD3_k127_2792285_5	517417.Cpar_0534	9.769e-11	66.0	COG3668@1|root,COG3668@2|Bacteria,1FFP3@1090|Chlorobi	1090|Chlorobi	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
YYD3_k127_2792285_7	391625.PPSIR1_29945	6.275e-07	54.0	2BBXM@1|root,325G4@2|Bacteria,1QAR0@1224|Proteobacteria,4358V@68525|delta/epsilon subdivisions,2WZK0@28221|Deltaproteobacteria,2Z2AE@29|Myxococcales	391625.PPSIR1_29945|-	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2792285_6	1157637.KB892095_gene2777	8.333e-10	64.0	28MKP@1|root,2ZAWT@2|Bacteria,2IJQ2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
YYD3_k127_2792285_4	1150600.ADIARSV_0455	5.617e-17	84.0	COG0662@1|root,COG0662@2|Bacteria,4PN7Z@976|Bacteroidetes,1J0NE@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_2799528_0	497964.CfE428DRAFT_2012	5.791e-64	235.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YYD3_k127_2799528_1	269798.CHU_1303	1.7e-29	127.0	COG1225@1|root,COG1225@2|Bacteria,4NXEC@976|Bacteroidetes	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2799717_0	266117.Rxyl_0336	4.367e-223	699.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria,4CSKA@84995|Rubrobacteria	84995|Rubrobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
YYD3_k127_2799717_1	639030.JHVA01000001_gene2810	5.69e-134	438.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,GerE,Trans_reg_C
YYD3_k127_2799717_2	243090.RB10458	1.143e-29	120.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_2799717_4	273057.SSO2390	2.343e-24	110.0	COG0221@1|root,arCOG01711@2157|Archaea,2XQB5@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YYD3_k127_2807821_2	1267533.KB906733_gene3215	7.372e-121	409.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_2807821_1	56107.Cylst_0633	1.071e-175	572.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1HKB6@1161|Nostocales	1117|Cyanobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
YYD3_k127_2807821_3	136993.KB900627_gene392	5.642e-25	118.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2807821_0	1123024.AUII01000035_gene1223	9.325e-194	617.0	COG2414@1|root,COG2414@2|Bacteria,2IF1J@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
YYD3_k127_2813740_1	1123368.AUIS01000004_gene285	4.536e-162	516.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,2NCA6@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C
YYD3_k127_2813740_0	204669.Acid345_2747	0.0	1122.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria,2JIA9@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
YYD3_k127_2813740_3	243231.GSU1402	7.781e-103	343.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,43UDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
YYD3_k127_2813740_2	203119.Cthe_1346	2.272e-141	471.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WI09@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
YYD3_k127_2813740_6	204669.Acid345_1660	0.0001763	55.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
YYD3_k127_2813740_4	671143.DAMO_1189	2.512e-98	332.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
YYD3_k127_2813740_5	667014.Thein_1402	1.694e-46	177.0	COG1508@1|root,COG1508@2|Bacteria,2GHDD@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YYD3_k127_2845780_9	522306.CAP2UW1_2584	2.301e-13	72.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YYD3_k127_2845780_7	1379698.RBG1_1C00001G0021	3.43e-24	106.0	COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330,ko:K05574	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YYD3_k127_2845780_3	1379698.RBG1_1C00001G0022	5.345e-61	223.0	COG0377@1|root,COG0377@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD3_k127_2845780_6	471852.Tcur_4386	8.212e-26	113.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria,4EIQ6@85012|Streptosporangiales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YYD3_k127_2845780_1	1379698.RBG1_1C00001G0024	6.211e-134	437.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333,ko:K05579,ko:K13378	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
YYD3_k127_2845780_2	552811.Dehly_0835	3.557e-87	301.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi,34CTC@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YYD3_k127_2845780_4	1379698.RBG1_1C00001G0026	5.87e-36	144.0	COG1143@1|root,COG1143@2|Bacteria,2NRUK@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3,1.6.99.3	ko:K00338,ko:K02573,ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Fer4,Fer4_7
YYD3_k127_2845780_8	264732.Moth_0983	3.771e-22	108.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,24NAC@186801|Clostridia,42GTX@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YYD3_k127_2845780_5	1379698.RBG1_1C00001G0028	3.932e-31	126.0	COG0713@1|root,COG0713@2|Bacteria,2NQ6R@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YYD3_k127_2845780_0	1379698.RBG1_1C00001G0029	1.307e-142	473.0	COG1009@1|root,COG1009@2|Bacteria,2NNM8@2323|unclassified Bacteria	2|Bacteria	CP	NADH-quinone oxidoreductase chain L	nuoL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00341,ko:K05577	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YYD3_k127_2850296_0	682795.AciX8_3255	1.932e-106	372.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
YYD3_k127_2880722_5	765420.OSCT_0523	4.089e-05	48.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
YYD3_k127_2880722_1	1380355.JNIJ01000016_gene5743	3.571e-166	529.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2TSCE@28211|Alphaproteobacteria,3JSZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_2880722_3	1267535.KB906767_gene1911	5.745e-87	295.0	COG4566@1|root,COG4566@2|Bacteria,3Y4GS@57723|Acidobacteria,2JJ1Z@204432|Acidobacteriia	204432|Acidobacteriia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_2880722_4	1267535.KB906767_gene1910	3.649e-45	172.0	COG4566@1|root,COG4566@2|Bacteria,3Y58V@57723|Acidobacteria,2JJQJ@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_2880722_0	1287116.X734_23605	1.142e-205	667.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
YYD3_k127_2880722_2	1476876.JOJO01000038_gene5975	2.688e-95	317.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria	201174|Actinobacteria	K	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
YYD3_k127_2900127_23	761193.Runsl_0962	1.094e-27	115.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47KIG@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17
YYD3_k127_2900127_9	1379270.AUXF01000007_gene1065	2.233e-101	349.0	COG1055@1|root,COG1055@2|Bacteria,1ZU8M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	MatC_N
YYD3_k127_2900127_29	1297742.A176_05743	1.097e-13	82.0	COG1011@1|root,COG1011@2|Bacteria,1RA0T@1224|Proteobacteria	1224|Proteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_2900127_28	1121924.ATWH01000001_gene4430	1.403e-15	87.0	COG2315@1|root,COG2315@2|Bacteria,2I2W9@201174|Actinobacteria,4FQ8P@85023|Microbacteriaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
YYD3_k127_2900127_11	378806.STAUR_6894	3.516e-87	300.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria	1224|Proteobacteria	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_2900127_12	479434.Sthe_1797	1.85e-85	296.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
YYD3_k127_2900127_4	204669.Acid345_1394	2.392e-160	517.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria,2JIIE@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2900127_6	1125863.JAFN01000001_gene1651	4.328e-129	440.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
YYD3_k127_2900127_16	204669.Acid345_4041	4.009e-62	217.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJC7@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YYD3_k127_2900127_21	1499967.BAYZ01000155_gene669	1.331e-35	151.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD3_k127_2900127_7	234267.Acid_5250	5.555e-116	384.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria	57723|Acidobacteria	F	PFAM SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
YYD3_k127_2900127_30	204669.Acid345_2260	4.592e-13	72.0	COG2204@1|root,COG2204@2|Bacteria,3Y98S@57723|Acidobacteria,2JP05@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
YYD3_k127_2900127_20	671143.DAMO_2458	3.69e-36	141.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YYD3_k127_2900127_0	234267.Acid_6747	6.214e-265	824.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD3_k127_2900127_27	1267535.KB906767_gene4740	8.764e-19	95.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_2900127_8	234267.Acid_4959	1.195e-109	401.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y63K@57723|Acidobacteria	57723|Acidobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
YYD3_k127_2900127_18	1123514.KB905899_gene689	8.494e-47	184.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S43R@1236|Gammaproteobacteria,460S0@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
YYD3_k127_2900127_15	713587.THITH_02335	1.205e-74	255.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_2900127_25	234267.Acid_1287	6.626e-25	115.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_2900127_24	1267533.KB906737_gene1630	1.159e-27	126.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_2900127_31	1121403.AUCV01000012_gene4073	8.812e-13	69.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MKX6@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
YYD3_k127_2900127_2	1345697.M493_15855	4.423e-200	649.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1WF8G@129337|Geobacillus	91061|Bacilli	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YYD3_k127_2900127_13	518766.Rmar_0944	1.176e-84	301.0	COG2379@1|root,COG2379@2|Bacteria,4NI08@976|Bacteroidetes,1FJ0H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
YYD3_k127_2900127_22	671143.DAMO_2528	5.26e-30	131.0	COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
YYD3_k127_2900127_14	1121920.AUAU01000005_gene1090	2.215e-75	260.0	COG2884@1|root,COG2884@2|Bacteria	2|Bacteria	D	Cell division ATP-binding protein ftsE	ftsE	GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
YYD3_k127_2900127_3	1123288.SOV_6c01940	1.013e-172	554.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4H327@909932|Negativicutes	909932|Negativicutes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YYD3_k127_2900127_1	945713.IALB_1142	3.437e-225	709.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
YYD3_k127_2900127_26	497964.CfE428DRAFT_5946	1.404e-19	98.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2900127_5	861299.J421_4428	4.867e-131	431.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YYD3_k127_2900127_32	401053.AciPR4_0694	2.049e-09	64.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
YYD3_k127_2900127_17	1047013.AQSP01000118_gene1234	2.282e-56	218.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
YYD3_k127_2900127_19	760568.Desku_0102	4.364e-45	184.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,261XD@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
YYD3_k127_2900127_10	396588.Tgr7_1732	3.145e-91	311.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WXV4@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD3_k127_292805_0	1267535.KB906767_gene5424	1.968e-124	413.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
YYD3_k127_2933555_30	234267.Acid_0464	4.31e-14	72.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YYD3_k127_2933555_1	330214.NIDE0372	2.381e-226	709.0	COG0055@1|root,COG0055@2|Bacteria,3J0BN@40117|Nitrospirae	40117|Nitrospirae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
YYD3_k127_2933555_27	204669.Acid345_4331	3.123e-31	127.0	COG0355@1|root,COG0355@2|Bacteria,3Y515@57723|Acidobacteria,2JJJV@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
YYD3_k127_2933555_14	1047013.AQSP01000132_gene1706	5.59e-74	258.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
YYD3_k127_2933555_4	1047013.AQSP01000132_gene1707	8.953e-134	438.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
YYD3_k127_2933555_20	1125863.JAFN01000001_gene3040	9.306e-46	176.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
YYD3_k127_2933555_0	204669.Acid345_4549	6.094e-285	917.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YYD3_k127_2933555_31	1123371.ATXH01000003_gene1945	5.025e-14	83.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
YYD3_k127_2933555_25	330214.NIDE2714	2.075e-35	143.0	COG0250@1|root,COG0250@2|Bacteria,3J17S@40117|Nitrospirae	40117|Nitrospirae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
YYD3_k127_2933555_12	370438.PTH_0259	2.366e-74	262.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,26001@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
YYD3_k127_2933555_34	937777.Deipe_0075	1.602e-10	74.0	COG2805@1|root,COG2805@2|Bacteria,1WI5S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Tfp pilus assembly protein pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_2933555_32	879212.DespoDRAFT_02407	6.365e-13	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI07@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2933555_16	525146.Ddes_0187	5.137e-68	246.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2933555_13	215803.DB30_1154	2.639e-74	263.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2YXVA@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2933555_19	1125863.JAFN01000001_gene381	2.308e-52	205.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
YYD3_k127_2933555_15	886293.Sinac_3190	3.479e-69	250.0	COG2204@1|root,COG2204@2|Bacteria,2IXMN@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2933555_35	1408813.AYMG01000039_gene2260	2.156e-05	51.0	2C85M@1|root,334CZ@2|Bacteria,4NQS4@976|Bacteroidetes,1ISR0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YYD3_k127_2933555_3	880072.Desac_2891	8.961e-137	452.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MQ9H@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_2933555_37	330214.NIDE0636	0.0002926	46.0	COG2452@1|root,COG2452@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281,HTH_17
YYD3_k127_2933555_23	675635.Psed_4731	2.398e-37	154.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4DZK1@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
YYD3_k127_2933555_10	357808.RoseRS_3026	4.183e-87	307.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
YYD3_k127_2933555_21	1125863.JAFN01000001_gene2653	1.642e-41	169.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
YYD3_k127_2933555_22	1444309.JAQG01000025_gene3857	1.708e-38	149.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,26XMB@186822|Paenibacillaceae	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YYD3_k127_2933555_5	278963.ATWD01000002_gene729	1.128e-117	402.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
YYD3_k127_2933555_38	379066.GAU_0202	0.000336	52.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
YYD3_k127_2933555_29	1288826.MSNKSG1_01293	2.558e-15	87.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,464ES@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_2933555_7	323098.Nwi_2169	3.774e-102	350.0	COG3746@1|root,COG3746@2|Bacteria,1R45W@1224|Proteobacteria,2U0GV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
YYD3_k127_2933555_8	933262.AXAM01000098_gene3457	4.775e-101	359.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
YYD3_k127_2933555_9	671143.DAMO_1616	1.503e-97	341.0	COG1034@1|root,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
YYD3_k127_2933555_11	1047013.AQSP01000083_gene1193	1.116e-77	290.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
YYD3_k127_2933555_17	204669.Acid345_0959	3.457e-59	220.0	COG2208@1|root,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
YYD3_k127_2933555_2	986075.CathTA2_2561	3.972e-150	484.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli	91061|Bacilli	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_2933555_18	326427.Cagg_1002	2.623e-53	213.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2933555_24	525904.Tter_1235	3.894e-36	150.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	yueF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
YYD3_k127_2933555_6	1519464.HY22_02880	2.084e-110	370.0	COG0436@1|root,COG0436@2|Bacteria,1FEMP@1090|Chlorobi	1090|Chlorobi	E	PFAM aminotransferase, class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YYD3_k127_2933555_28	234267.Acid_5910	8.245e-29	128.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_2933555_26	588932.JHOF01000027_gene1613	2.405e-31	132.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_2933555_36	1173021.ALWA01000013_gene2885	7.884e-05	45.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,Thioesterase
YYD3_k127_2938925_1	69395.JQLZ01000012_gene4283	9.105e-06	56.0	COG1266@1|root,COG1266@2|Bacteria,1NFV7@1224|Proteobacteria,2V70Q@28211|Alphaproteobacteria,2KJMQ@204458|Caulobacterales	204458|Caulobacterales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YYD3_k127_2938925_0	861299.J421_0074	6.754e-17	91.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YYD3_k127_293967_1	263358.VAB18032_27736	6.584e-148	491.0	COG5276@1|root,COG5276@2|Bacteria,2IAAZ@201174|Actinobacteria,4DBJS@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,P_proprotein
YYD3_k127_293967_7	234267.Acid_3837	7.702e-31	141.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_293967_9	1089550.ATTH01000001_gene1889	4.801e-16	91.0	COG0729@1|root,COG0729@2|Bacteria,4PF0B@976|Bacteroidetes,1FJXS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD3_k127_293967_6	304371.MCP_0732	4.244e-39	149.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD3_k127_293967_2	1340493.JNIF01000003_gene3161	1.54e-142	491.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_293967_0	1288494.EBAPG3_30870	2.166e-149	479.0	COG2304@1|root,COG2304@2|Bacteria,1PXCB@1224|Proteobacteria,2WCTS@28216|Betaproteobacteria,374DH@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	Tyrosinase
YYD3_k127_293967_3	1336208.JADY01000020_gene3413	7.446e-137	442.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
YYD3_k127_293967_4	264198.Reut_B5776	1.179e-119	396.0	COG2159@1|root,COG2159@2|Bacteria,1R7NS@1224|Proteobacteria,2WG6X@28216|Betaproteobacteria,1KIAN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YYD3_k127_293967_10	1449063.JMLS01000026_gene3861	1.268e-09	71.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,4HCR6@91061|Bacilli,26S7G@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
YYD3_k127_293967_8	1452535.JARD01000029_gene899	4.873e-29	119.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FP0M@85023|Microbacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
YYD3_k127_2944904_0	234267.Acid_5180	1.646e-169	537.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YYD3_k127_2944904_1	234267.Acid_5179	4.114e-47	173.0	COG0779@1|root,COG0779@2|Bacteria,3Y528@57723|Acidobacteria	57723|Acidobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
YYD3_k127_2982106_8	335543.Sfum_0084	1.16e-22	100.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_2982106_1	909663.KI867150_gene1265	7.138e-223	708.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MQ7P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YYD3_k127_2982106_0	479434.Sthe_0441	0.0	1149.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD3_k127_2982106_5	525904.Tter_2296	1.42e-91	311.0	COG0484@1|root,COG0484@2|Bacteria,2NQI8@2323|unclassified Bacteria	2|Bacteria	O	DnaJ molecular chaperone homology domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
YYD3_k127_2982106_9	309801.trd_0442	7.914e-20	98.0	COG0789@1|root,COG0789@2|Bacteria,2G72X@200795|Chloroflexi,27YHN@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
YYD3_k127_2982106_6	886293.Sinac_6240	1.343e-43	168.0	COG0861@1|root,COG0861@2|Bacteria,2J0FS@203682|Planctomycetes	203682|Planctomycetes	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
YYD3_k127_2982106_2	497964.CfE428DRAFT_1447	2.166e-153	509.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
YYD3_k127_2982106_3	497964.CfE428DRAFT_1447	7.348e-129	425.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
YYD3_k127_2982106_4	497964.CfE428DRAFT_0997	4.381e-114	393.0	COG0744@1|root,COG0744@2|Bacteria,46U6K@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YYD3_k127_2982106_7	1121861.KB899917_gene3614	2.231e-32	130.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2JQMB@204441|Rhodospirillales	204441|Rhodospirillales	L	COG2818 3-methyladenine DNA glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YYD3_k127_2989543_7	234267.Acid_6439	2.356e-66	256.0	COG1752@1|root,COG1752@2|Bacteria,3Y6N9@57723|Acidobacteria	57723|Acidobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
YYD3_k127_2989543_15	330214.NIDE1528	7.946e-32	134.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
YYD3_k127_2989543_9	330214.NIDE1529	1.914e-54	201.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
YYD3_k127_2989543_4	379066.GAU_3834	8.47e-73	268.0	COG0515@1|root,COG0515@2|Bacteria	379066.GAU_3834|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
YYD3_k127_2989543_16	643562.Daes_2568	1.036e-23	111.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,42R9E@68525|delta/epsilon subdivisions,2WNRJ@28221|Deltaproteobacteria,2MAXH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YYD3_k127_2989543_17	278963.ATWD01000001_gene4031	0.000392	44.0	COG1917@1|root,COG1917@2|Bacteria,3Y5JM@57723|Acidobacteria,2JN7Y@204432|Acidobacteriia	204432|Acidobacteriia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_2989543_6	136993.KB900627_gene392	2.993e-67	250.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2989543_12	136993.KB900627_gene393	3.638e-35	153.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2989543_14	639030.JHVA01000001_gene1885	4.859e-32	134.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2989543_13	1165096.ARWF01000001_gene429	1.137e-34	141.0	2FIXR@1|root,312JV@2|Bacteria,1NBAI@1224|Proteobacteria,2W83G@28216|Betaproteobacteria,2KNQ3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
YYD3_k127_2989543_3	861299.J421_1634	3.73e-93	324.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
YYD3_k127_2989543_11	1227739.Hsw_2936	3.485e-37	144.0	2DNUQ@1|root,32Z94@2|Bacteria,4NVH0@976|Bacteroidetes,47QAG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
YYD3_k127_2989543_5	1449346.JQMO01000002_gene153	1.634e-71	252.0	28PB4@1|root,2ZC42@2|Bacteria,2GP5R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2989543_10	525368.HMPREF0591_2130	1.69e-37	153.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,2391H@1762|Mycobacteriaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
YYD3_k127_2989543_0	365044.Pnap_3599	0.0	1012.0	COG4772@1|root,COG4772@2|Bacteria,1MXJU@1224|Proteobacteria,2VN9X@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_2989543_1	886293.Sinac_1153	2.556e-189	627.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_2989543_2	595460.RRSWK_05343	4.038e-94	332.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_2989543_8	1379270.AUXF01000003_gene3619	6.5e-62	242.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2993088_2	167555.NATL1_18651	3.476e-06	48.0	COG0015@1|root,COG0015@2|Bacteria,1G07M@1117|Cyanobacteria,1MM0H@1212|Prochloraceae	1117|Cyanobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YYD3_k127_2993088_0	234267.Acid_7201	3.642e-138	451.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_2993088_1	1125863.JAFN01000001_gene1383	1.143e-101	343.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
YYD3_k127_299955_0	443598.AUFA01000049_gene415	3.375e-140	470.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Abhydrolase_1,DZR,Guanylate_cyc,TPR_4
YYD3_k127_3010248_1	1500894.JQNN01000001_gene650	9.824e-30	125.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria	1224|Proteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YYD3_k127_3010248_0	935567.JAES01000019_gene1025	8.897e-89	304.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1MVI4@1224|Proteobacteria,1S1IH@1236|Gammaproteobacteria,1X71U@135614|Xanthomonadales	135614|Xanthomonadales	M	peptidoglycan-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
YYD3_k127_3047850_0	1232410.KI421415_gene3125	2.913e-102	349.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3047850_2	290397.Adeh_3342	2.056e-37	159.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
YYD3_k127_3047850_6	522373.Smlt0034	3.006e-18	91.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,1S4U7@1236|Gammaproteobacteria,1X7U5@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3047850_4	234267.Acid_2360	8.923e-31	132.0	COG0671@1|root,COG0671@2|Bacteria,3Y8KF@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YYD3_k127_3047850_3	1047013.AQSP01000089_gene1178	2.859e-34	151.0	COG3227@1|root,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	gelE	-	3.4.24.28,3.4.24.30	ko:K01400,ko:K08605,ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
YYD3_k127_3047850_1	446462.Amir_3933	4.922e-100	363.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4E0TN@85010|Pseudonocardiales	201174|Actinobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612,ko:K16035	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09853,R09858	RC00055,RC02840	ko00000,ko00001,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YYD3_k127_3047850_7	319236.JCM19294_1981	6.188e-08	65.0	COG0381@1|root,COG0381@2|Bacteria,4P4KA@976|Bacteroidetes,1I9GS@117743|Flavobacteriia,3HKWN@363408|Nonlabens	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	MGDG_synth
YYD3_k127_3047850_5	1167006.UWK_00092	1.473e-29	123.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MHQS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YYD3_k127_3077844_0	204669.Acid345_4012	2.094e-07	64.0	2DBAV@1|root,2Z84I@2|Bacteria,3Y2PF@57723|Acidobacteria,2JIIF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3080606_3	401053.AciPR4_3363	1.068e-44	188.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3080606_4	1165096.ARWF01000001_gene433	3.298e-39	160.0	COG0607@1|root,COG3386@1|root,COG0607@2|Bacteria,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VHGN@28216|Betaproteobacteria,2KNEV@206350|Nitrosomonadales	206350|Nitrosomonadales	GP	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
YYD3_k127_3080606_7	1267533.KB906734_gene4002	1.007e-11	72.0	COG0577@1|root,COG0577@2|Bacteria	1267533.KB906734_gene4002|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3080606_2	448385.sce0758	2.838e-55	197.0	COG2169@1|root,COG2169@2|Bacteria,1NICQ@1224|Proteobacteria,43EDD@68525|delta/epsilon subdivisions,2X81D@28221|Deltaproteobacteria,2Z3J7@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YYD3_k127_3080606_1	1254432.SCE1572_39360	1.322e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,43827@68525|delta/epsilon subdivisions,2X3CD@28221|Deltaproteobacteria,2YVE1@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_3080606_6	682795.AciX8_1038	9.872e-16	88.0	COG2304@1|root,COG2304@2|Bacteria,3Y7I6@57723|Acidobacteria,2JMVP@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YYD3_k127_3080606_0	1300345.LF41_2983	3.037e-91	308.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Cellulase,NHL,RicinB_lectin_2
YYD3_k127_3080606_5	1121373.KB903621_gene1862	7.313e-30	123.0	COG3852@1|root,COG3852@2|Bacteria,4P3WV@976|Bacteroidetes	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
YYD3_k127_3084883_0	861299.J421_5846	1.166e-136	454.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
YYD3_k127_3084883_1	1306174.JODP01000006_gene3444	0.000955	49.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
YYD3_k127_3125305_6	867903.ThesuDRAFT_01030	5.148e-42	160.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YYD3_k127_3125305_1	867903.ThesuDRAFT_01029	3.52e-131	431.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YYD3_k127_3125305_4	1144275.COCOR_03729	1.845e-63	227.0	COG0321@1|root,COG0494@1|root,COG0321@2|Bacteria,COG0494@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
YYD3_k127_3125305_2	234267.Acid_0914	1.553e-129	428.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_3125305_0	1242864.D187_009915	5.997e-145	473.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD3_k127_3125305_3	269799.Gmet_2453	2.284e-109	371.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43TS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3125305_9	945713.IALB_0305	8.37e-20	93.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YYD3_k127_3125305_5	886293.Sinac_6582	2.06e-42	158.0	COG0780@1|root,COG0780@2|Bacteria,2J07W@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
YYD3_k127_3125305_8	1192034.CAP_6891	6.385e-21	96.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YYD3_k127_3125305_7	1267535.KB906767_gene2048	5.707e-33	138.0	COG0553@1|root,COG0553@2|Bacteria,3Y8RT@57723|Acidobacteria	57723|Acidobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
YYD3_k127_3162740_3	247633.GP2143_17796	5.077e-34	141.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3162740_0	504472.Slin_4695	2.924e-212	677.0	28JZQ@1|root,2Z9PN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3162740_6	215803.DB30_1378	2.358e-07	59.0	COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria,432Z6@68525|delta/epsilon subdivisions,2WXKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YYD3_k127_3162740_4	555793.WSK_4047	5.273e-25	115.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3162740_5	555793.WSK_4047	5.493e-21	106.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3162740_2	1267534.KB906756_gene683	6.66e-122	400.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	ko:K03420,ko:K13525,ko:K17681	ko03050,ko04141,ko05134,map03050,map04141,map05134	M00343,M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko03029,ko03051,ko04131,ko04147	3.A.16.1	-	-	AAA
YYD3_k127_3162740_1	443143.GM18_3484	2.918e-148	489.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WIK4@28221|Deltaproteobacteria,43T2X@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YYD3_k127_3164627_2	395965.Msil_0410	1.472e-34	152.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3164627_0	1120965.AUBV01000004_gene739	7.95e-111	374.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_3164627_1	234267.Acid_2071	4.89e-50	180.0	COG0738@1|root,COG0738@2|Bacteria,3Y723@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_3173875_0	234267.Acid_1154	2.153e-162	544.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_3173875_2	682795.AciX8_0965	4.193e-10	64.0	COG1629@1|root,COG4771@2|Bacteria,3Y3BR@57723|Acidobacteria,2JKS3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3173875_1	1313301.AUGC01000016_gene871	6.472e-22	107.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
YYD3_k127_3173875_3	382464.ABSI01000012_gene2201	2.662e-05	48.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
YYD3_k127_3194084_3	1459636.NTE_00013	7.003e-64	226.0	COG2085@1|root,arCOG00457@2157|Archaea	2157|Archaea	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored,HTH_10
YYD3_k127_3194084_0	1267535.KB906767_gene2552	0.0	1257.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria,2JMMF@204432|Acidobacteriia	204432|Acidobacteriia	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
YYD3_k127_3194084_4	1237149.C900_02500	5.778e-06	50.0	COG2085@1|root,COG2085@2|Bacteria,4NQ1G@976|Bacteroidetes,47Q30@768503|Cytophagia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
YYD3_k127_3194084_1	1267535.KB906767_gene3571	3.073e-209	691.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_3194084_2	1340493.JNIF01000003_gene3330	9.045e-92	303.0	COG3865@1|root,COG3865@2|Bacteria,3Y4UB@57723|Acidobacteria	57723|Acidobacteria	H	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
YYD3_k127_3200818_3	1144275.COCOR_07165	2.631e-10	63.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,43850@68525|delta/epsilon subdivisions,2WX9Z@28221|Deltaproteobacteria,2YWVT@29|Myxococcales	28221|Deltaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD3_k127_3200818_1	234267.Acid_4171	4.099e-58	214.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3200818_0	1121106.JQKB01000003_gene2541	8.175e-121	401.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,2JVWB@204441|Rhodospirillales	204441|Rhodospirillales	G	Malonyl-CoA decarboxylase N-terminal domain	-	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
YYD3_k127_3200818_2	278963.ATWD01000001_gene3210	1.981e-39	150.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_3200966_0	1007096.BAGW01000007_gene1894	3.426e-101	342.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,2N6JB@216572|Oscillospiraceae	186801|Clostridia	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
YYD3_k127_3200966_4	272559.BF9343_3862	3.079e-21	102.0	COG3404@1|root,COG3404@2|Bacteria,4NN2J@976|Bacteroidetes,2FPSN@200643|Bacteroidia,4AMB8@815|Bacteroidaceae	976|Bacteroidetes	E	COG3404 Methenyl tetrahydrofolate cyclohydrolase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C,Peptidase_M78
YYD3_k127_3200966_2	690850.Desaf_1038	8.12e-57	208.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M9N8@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD3_k127_3200966_3	941449.dsx2_2402	1.114e-23	104.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M9N8@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD3_k127_3200966_1	533247.CRD_02890	2e-65	229.0	COG0090@1|root,COG0090@2|Bacteria,1G1P7@1117|Cyanobacteria,1HKZQ@1161|Nostocales	1117|Cyanobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YYD3_k127_3214981_0	1283287.KB822578_gene2446	1.294e-213	675.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4DPQG@85009|Propionibacteriales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YYD3_k127_3214981_2	1379270.AUXF01000007_gene1056	2.723e-92	312.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
YYD3_k127_3214981_3	1321775.HMPREF1980_00360	0.0009086	50.0	COG1470@1|root,COG2373@1|root,COG4932@1|root,COG1470@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,2I66Z@201174|Actinobacteria,4D38B@85005|Actinomycetales	201174|Actinobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
YYD3_k127_3214981_1	234267.Acid_5856	3.141e-133	445.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_324237_3	743721.Psesu_1582	6.976e-05	50.0	2CEN7@1|root,2Z9XA@2|Bacteria,1NQTA@1224|Proteobacteria,1SXXD@1236|Gammaproteobacteria,1X6YN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_324237_2	1267535.KB906767_gene420	8.114e-09	61.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_324237_0	1163617.SCD_n02012	4.377e-112	377.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_324237_1	443598.AUFA01000028_gene7138	1.048e-36	143.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
YYD3_k127_3247686_0	1340493.JNIF01000003_gene3965	2.745e-121	404.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_3252074_0	1122201.AUAZ01000009_gene2863	1.742e-116	380.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,466E6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	epimerase, PhzC PhzF homolog	pab	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
YYD3_k127_3252074_2	93220.LV28_02775	2.529e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_3252074_1	1122201.AUAZ01000005_gene488	7.76e-64	226.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,464MN@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_325247_0	530564.Psta_0825	6.874e-139	452.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2IY3H@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
YYD3_k127_325247_2	234267.Acid_3571	4.679e-50	196.0	COG0558@1|root,COG0558@2|Bacteria,3Y4PW@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
YYD3_k127_325247_1	1499967.BAYZ01000026_gene1617	1.029e-64	229.0	COG0178@1|root,COG0178@2|Bacteria,2NQR8@2323|unclassified Bacteria	2|Bacteria	L	ABC transporter	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YYD3_k127_325453_1	1047013.AQSP01000100_gene599	2.614e-32	147.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_325453_0	136993.KB900626_gene2612	5.352e-45	183.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3262680_0	1267535.KB906767_gene656	4.493e-225	707.0	COG1032@1|root,COG1032@2|Bacteria,3Y2FN@57723|Acidobacteria,2JI6W@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_3262680_1	234267.Acid_2664	1.932e-206	651.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
YYD3_k127_3262680_4	661478.OP10G_2561	1.3e-86	295.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
YYD3_k127_3262680_6	1267534.KB906760_gene1243	1.055e-28	135.0	COG1629@1|root,COG1629@2|Bacteria,3Y98Z@57723|Acidobacteria,2JI5U@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3262680_3	443143.GM18_4080	1.3e-116	407.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WJ5T@28221|Deltaproteobacteria,43SYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg,dCache_1
YYD3_k127_3262680_5	661478.OP10G_3269	4.237e-60	221.0	COG2089@1|root,COG2089@2|Bacteria	2|Bacteria	M	N-acylneuraminate-9-phosphate synthase activity	neuB	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
YYD3_k127_3262680_11	515635.Dtur_0589	9.573e-05	49.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	ATP-grasp_3,HAD_2
YYD3_k127_3262680_10	857087.Metme_3994	9.743e-07	60.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,1RYTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Spore coat polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Glyco_tran_28_C
YYD3_k127_3262680_7	215803.DB30_2933	3.351e-26	127.0	COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,439J0@68525|delta/epsilon subdivisions,2X4VG@28221|Deltaproteobacteria,2YZPG@29|Myxococcales	28221|Deltaproteobacteria	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_3262680_8	401053.AciPR4_3185	6.79e-15	86.0	COG0454@1|root,COG0456@2|Bacteria,3Y32K@57723|Acidobacteria,2JP2F@204432|Acidobacteriia	204432|Acidobacteriia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_3262680_2	398767.Glov_2245	1.104e-116	391.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3262680_9	1192034.CAP_0356	7.082e-10	61.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,439XR@68525|delta/epsilon subdivisions,2WVH6@28221|Deltaproteobacteria,2Z0UX@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_3265289_0	330214.NIDE3498	1.724e-73	260.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
YYD3_k127_3265289_2	1173024.KI912151_gene1963	1.467e-43	171.0	COG4803@1|root,COG4803@2|Bacteria,1GJPE@1117|Cyanobacteria,1JJCG@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
YYD3_k127_3265289_1	859657.RPSI07_mp0397	4.099e-48	193.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,2VT7T@28216|Betaproteobacteria,1KHDD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
YYD3_k127_3265289_5	1123504.JQKD01000007_gene3356	7.712e-05	55.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD3_k127_3289441_2	420662.Mpe_A1812	3.485e-27	116.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1KKET@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YYD3_k127_3289441_0	330214.NIDE4312	3.514e-139	451.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD3_k127_3289441_4	509635.N824_12645	5.895e-12	72.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
YYD3_k127_3289441_3	1121920.AUAU01000030_gene2713	2.179e-23	110.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3289441_1	395964.KE386496_gene484	4.058e-65	227.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,3NCDJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YYD3_k127_3289441_5	935548.KI912159_gene622	3.652e-08	55.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TU9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Cytosine deaminase and related metal-dependent hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_3324126_0	74547.PMT_0541	0.0	1091.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1G2E2@1117|Cyanobacteria,1MMDC@1212|Prochloraceae	1117|Cyanobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
YYD3_k127_3324126_1	1297865.APJD01000003_gene6495	5.491e-215	687.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD3_k127_3324126_9	234267.Acid_6849	1.331e-10	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,DHC
YYD3_k127_3324126_4	1382304.JNIL01000001_gene3207	2.486e-97	321.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YYD3_k127_3324126_2	1198114.AciX9_0825	4.479e-148	479.0	COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria,2JHY8@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YYD3_k127_3324126_3	391625.PPSIR1_11756	3.305e-144	466.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2YYN9@29|Myxococcales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
YYD3_k127_3324126_6	1489678.RDMS_08110	9.782e-47	179.0	COG2102@1|root,COG2102@2|Bacteria,1WMKE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
YYD3_k127_3324126_5	304371.MCP_1094	6.111e-65	237.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,2NA71@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YYD3_k127_3324126_7	1131269.AQVV01000127_gene1621	1.469e-20	97.0	COG0609@1|root,COG0609@2|Bacteria	2|Bacteria	P	iron ion homeostasis	btuC	-	-	ko:K02015,ko:K06073	ko02010,map02010	M00240,M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13,3.A.1.14	-	-	FecCD
YYD3_k127_3343716_0	292459.STH3193	1.687e-135	437.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
YYD3_k127_3343716_1	1205753.A989_03796	2.543e-41	164.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,1X353@135614|Xanthomonadales	135614|Xanthomonadales	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
YYD3_k127_3351105_2	1403819.BATR01000191_gene6569	2.635e-08	55.0	COG3119@1|root,COG3119@2|Bacteria,46YYP@74201|Verrucomicrobia,2ITHV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
YYD3_k127_3351105_1	67315.JOBD01000060_gene330	1.82e-14	83.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
YYD3_k127_3351105_0	204669.Acid345_4390	6.718e-122	424.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_3400698_2	404589.Anae109_2797	7.621e-22	99.0	COG4974@1|root,COG4974@2|Bacteria,1Q4H1@1224|Proteobacteria,43A00@68525|delta/epsilon subdivisions,2X29E@28221|Deltaproteobacteria,2YZ6M@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
YYD3_k127_3400698_0	1250006.JHZZ01000001_gene763	1.415e-44	168.0	28KP8@1|root,2ZA7D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3400698_3	1229172.JQFA01000002_gene4730	9.112e-22	96.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HC3P@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
YYD3_k127_3400698_1	706587.Desti_5217	8.018e-28	115.0	2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3400698_4	497965.Cyan7822_0272	3.527e-17	85.0	2E90H@1|root,3339X@2|Bacteria,1G9EW@1117|Cyanobacteria,3KJ2F@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3416856_4	1345697.M493_14015	6.159e-49	187.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1WFCH@129337|Geobacillus	91061|Bacilli	J	Ferredoxin-fold anticodon binding domain	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YYD3_k127_3416856_11	555079.Toce_1395	1.237e-10	66.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,25B8U@186801|Clostridia,42JED@68295|Thermoanaerobacterales	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
YYD3_k127_3416856_3	1128421.JAGA01000002_gene1502	1.114e-64	235.0	COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU05900	AIRS,AIRS_C
YYD3_k127_3416856_9	234267.Acid_4979	6.32e-15	83.0	COG3584@1|root,COG3584@2|Bacteria,3Y8W5@57723|Acidobacteria	57723|Acidobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
YYD3_k127_3416856_7	696369.KI912183_gene1207	2.148e-28	123.0	COG0500@1|root,COG0500@2|Bacteria,1VJS9@1239|Firmicutes,24TBM@186801|Clostridia	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_3416856_2	1382359.JIAL01000001_gene1619	1.889e-71	269.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
YYD3_k127_3416856_14	864702.OsccyDRAFT_4029	3.423e-05	57.0	COG1426@1|root,COG1426@2|Bacteria,1G72S@1117|Cyanobacteria,1HBXP@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
YYD3_k127_3416856_5	401053.AciPR4_3363	6.085e-42	179.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3416856_0	882378.RBRH_00333	8.332e-118	390.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GerE,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg
YYD3_k127_3416856_6	1396418.BATQ01000179_gene3160	1.756e-29	132.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,46US9@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
YYD3_k127_3416856_10	1523503.JPMY01000023_gene966	9.09e-12	77.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1MU9B@1224|Proteobacteria,1S0J1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis protein	wspA	-	-	ko:K03406,ko:K13487	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
YYD3_k127_3416856_1	1125863.JAFN01000001_gene746	2.345e-116	395.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3416856_13	485913.Krac_10238	1.352e-05	56.0	COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,2G7XD@200795|Chloroflexi	200795|Chloroflexi	NT	InterProIPR000673 IPR000780 IPR013656 IPR003661 IPR 003594 IPR005467 IPR009082	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c
YYD3_k127_3416856_8	246197.MXAN_1552	1.025e-24	109.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_3422250_7	555793.WSK_3225	4.376e-25	109.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3422250_5	1151127.KB906325_gene4573	5.994e-44	169.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3422250_8	1088721.NSU_2823	5.892e-16	87.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3422250_6	555793.WSK_3236	2.976e-27	116.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3422250_3	448385.sce6416	4.682e-69	237.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,439P5@68525|delta/epsilon subdivisions,2X50M@28221|Deltaproteobacteria,2YZXZ@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_3422250_0	1121920.AUAU01000005_gene969	8.047e-183	580.0	COG4941@1|root,COG4941@2|Bacteria,3Y38B@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_3422250_4	177439.DP2251	6.131e-53	195.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2WPDU@28221|Deltaproteobacteria,2MK9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
YYD3_k127_3422250_1	84531.JMTZ01000070_gene1802	1.076e-164	526.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,1RPX7@1236|Gammaproteobacteria,1X5IE@135614|Xanthomonadales	135614|Xanthomonadales	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
YYD3_k127_3422250_2	1210884.HG799465_gene12248	2.732e-146	470.0	COG3186@1|root,COG3186@2|Bacteria	2|Bacteria	E	Phenylalanine-4-hydroxylase	phhA	GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
YYD3_k127_3424927_1	1206732.BAGD01000057_gene2167	3.273e-39	152.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria,4G0IN@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_3424927_2	204669.Acid345_1284	7.289e-39	147.0	COG1695@1|root,COG1695@2|Bacteria,3Y5C5@57723|Acidobacteria,2JNCX@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_3424927_0	1183438.GKIL_4354	1.687e-176	587.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_3424927_3	497964.CfE428DRAFT_5423	5.932e-18	89.0	2EPF9@1|root,33H1X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3483855_1	326427.Cagg_1619	4.047e-70	245.0	COG1028@1|root,COG1028@2|Bacteria,2GAK3@200795|Chloroflexi,3774Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD3_k127_3483855_0	234267.Acid_5749	1.087e-150	508.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_3483855_2	682795.AciX8_3374	8.954e-20	95.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_3494842_11	1499967.BAYZ01000074_gene2162	2.978e-16	81.0	COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase, YajC	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
YYD3_k127_3494842_1	1047013.AQSP01000034_gene1652	3.993e-135	447.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YYD3_k127_3494842_5	1198114.AciX9_3623	1.031e-67	242.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
YYD3_k127_3494842_4	648757.Rvan_3491	1.339e-72	254.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,3N6R7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YYD3_k127_3494842_7	289376.THEYE_A1869	5.461e-39	155.0	COG2928@1|root,COG2928@2|Bacteria,3J0R2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
YYD3_k127_3494842_0	204669.Acid345_1918	0.0	1156.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YYD3_k127_3494842_8	1267535.KB906767_gene4740	7.338e-38	151.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_3494842_6	1340493.JNIF01000003_gene1848	9.477e-64	228.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
YYD3_k127_3494842_9	290318.Cvib_1166	1.569e-23	105.0	COG0848@1|root,COG0848@2|Bacteria,1FE3A@1090|Chlorobi	1090|Chlorobi	D	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
YYD3_k127_3494842_10	379066.GAU_2008	1.17e-19	96.0	COG0848@1|root,COG0848@2|Bacteria,1ZTXP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
YYD3_k127_3494842_2	518766.Rmar_0400	1.056e-123	410.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1FJY0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
YYD3_k127_3494842_3	861299.J421_4166	2.439e-79	274.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3494842_12	497964.CfE428DRAFT_3145	4.111e-06	50.0	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
YYD3_k127_3504451_0	452637.Oter_4060	8.116e-68	240.0	COG0345@1|root,COG0345@2|Bacteria	2|Bacteria	E	pyrroline-5-carboxylate reductase activity	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
YYD3_k127_3504451_4	497964.CfE428DRAFT_1911	1.015e-25	111.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM regulatory protein ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YYD3_k127_3504451_3	404589.Anae109_3644	1.255e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,42VTU@68525|delta/epsilon subdivisions,2WRGJ@28221|Deltaproteobacteria,2YVHK@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
YYD3_k127_3504451_2	187272.Mlg_2711	9.573e-35	136.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor arsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
YYD3_k127_3504451_1	395019.Bmul_5668	1.578e-46	174.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2VK65@28216|Betaproteobacteria,1K4KH@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Arsenite-activated ATPase (ArsA)	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
YYD3_k127_3510817_11	518766.Rmar_2323	5.87e-24	103.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1FIMG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YYD3_k127_3510817_10	479434.Sthe_0107	6.682e-28	120.0	COG1846@1|root,COG1846@2|Bacteria,2G941@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
YYD3_k127_3510817_4	861299.J421_2015	2.203e-80	293.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD3_k127_3510817_3	861299.J421_2016	5.215e-85	294.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD3_k127_3510817_0	1144275.COCOR_00464	0.0	1234.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
YYD3_k127_3510817_5	234267.Acid_0345	6.651e-77	268.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
YYD3_k127_3510817_14	1273538.G159_10695	0.0001453	51.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,26EZ4@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4115)	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
YYD3_k127_3510817_1	240016.ABIZ01000001_gene5783	1.009e-159	514.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia,2ITJM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase
YYD3_k127_3510817_6	927677.ALVU02000001_gene4110	2.332e-66	233.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_3510817_8	1165096.ARWF01000001_gene2279	5.393e-52	193.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	DUF2318,FTR1
YYD3_k127_3510817_2	1463901.JOIY01000027_gene4021	4.942e-101	344.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_3510817_7	2002.JOEQ01000012_gene5594	1.398e-65	238.0	COG0823@1|root,COG0823@2|Bacteria,2GK0R@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD3_k127_3510817_13	1521187.JPIM01000090_gene1830	2.93e-19	92.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
YYD3_k127_3510817_9	234267.Acid_3666	3.369e-38	157.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
YYD3_k127_3510817_12	63737.Npun_F4488	4.529e-20	102.0	2A5JH@1|root,30U9U@2|Bacteria,1GK5Q@1117|Cyanobacteria,1HTB6@1161|Nostocales	1117|Cyanobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
YYD3_k127_3540612_0	292459.STH2558	1.076e-206	659.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YYD3_k127_3540612_3	204669.Acid345_0713	5.491e-60	213.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria,2JIGK@204432|Acidobacteriia	204432|Acidobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YYD3_k127_3540612_5	240015.ACP_2247	3.71e-17	83.0	COG0291@1|root,COG0291@2|Bacteria,3Y5GU@57723|Acidobacteria,2JJX5@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YYD3_k127_3540612_4	204669.Acid345_0715	8.392e-39	148.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YYD3_k127_3540612_1	648996.Theam_1203	4.92e-112	372.0	COG0016@1|root,COG0016@2|Bacteria,2G4K6@200783|Aquificae	200783|Aquificae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YYD3_k127_3540612_2	1125863.JAFN01000001_gene1869	1.018e-103	358.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YYD3_k127_355294_3	530564.Psta_4030	2.254e-20	95.0	COG5507@1|root,COG5507@2|Bacteria,2J071@203682|Planctomycetes	203682|Planctomycetes	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
YYD3_k127_355294_0	880074.BARVI_03030	9.048e-153	503.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,2G105@200643|Bacteroidia,22YWU@171551|Porphyromonadaceae	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_355294_2	572546.Arcpr_1334	3.348e-58	219.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YYD3_k127_355294_1	580332.Slit_1573	1.822e-123	404.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,44W51@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
YYD3_k127_355294_4	756067.MicvaDRAFT_2760	0.0003718	44.0	COG1585@1|root,COG1585@2|Bacteria,1G215@1117|Cyanobacteria,1HAFI@1150|Oscillatoriales	1117|Cyanobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
YYD3_k127_3559300_1	861299.J421_1344	1.082e-27	116.0	COG0262@1|root,COG0262@2|Bacteria,1ZVA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YYD3_k127_3559300_0	1144312.PMI09_05026	5.15e-78	273.0	COG0300@1|root,COG0300@2|Bacteria,1N4CC@1224|Proteobacteria,2U8UA@28211|Alphaproteobacteria,4BM51@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
YYD3_k127_3559300_2	1267535.KB906767_gene1193	1.369e-11	66.0	2E8II@1|root,332WK@2|Bacteria,3Y5J0@57723|Acidobacteria,2JNE0@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3565058_5	247490.KSU1_D0355	7.168e-06	48.0	COG0467@1|root,COG0467@2|Bacteria,2IZBF@203682|Planctomycetes	203682|Planctomycetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
YYD3_k127_3565058_0	234267.Acid_2590	7.131e-93	325.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
YYD3_k127_3565058_3	234267.Acid_2589	9.088e-29	129.0	28U6K@1|root,2ZGCA@2|Bacteria,3Y8UV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3565058_4	234267.Acid_2588	4.497e-23	111.0	290DP@1|root,2ZN31@2|Bacteria,3Y8WY@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD3_k127_3565058_1	234267.Acid_2587	1.063e-54	198.0	COG1595@1|root,COG1595@2|Bacteria,3Y87A@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
YYD3_k127_3565058_2	392499.Swit_0250	1.846e-34	141.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2K1KM@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3577856_1	1120973.AQXL01000112_gene1069	1.57e-27	112.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,2789R@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YYD3_k127_3577856_0	404380.Gbem_0930	1.777e-181	576.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_3582504_0	717785.HYPMC_1838	0.0	1142.0	COG0463@1|root,COG0463@2|Bacteria,1NX2X@1224|Proteobacteria,2U364@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glycos_transf_2,Methyltransf_24
YYD3_k127_3606876_2	1502850.FG91_01261	2.834e-13	81.0	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,2U85Z@28211|Alphaproteobacteria,2K8U6@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_3606876_3	439235.Dalk_3699	2.728e-12	78.0	2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MKRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YYD3_k127_3606876_0	1131269.AQVV01000015_gene2005	1.074e-33	138.0	COG2802@1|root,COG2802@2|Bacteria	2|Bacteria	S	histone H2A-K13 ubiquitination	lonD	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
YYD3_k127_3606876_5	378806.STAUR_3149	3.236e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1PDHU@1224|Proteobacteria,4395I@68525|delta/epsilon subdivisions,2X4BX@28221|Deltaproteobacteria,2YYQ5@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
YYD3_k127_3606876_4	234267.Acid_4306	9.793e-06	48.0	COG2960@1|root,COG2960@2|Bacteria,3Y7EA@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_3628493_2	234267.Acid_3123	2.374e-35	143.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_3628493_0	234267.Acid_4577	8.356e-165	535.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_3628493_1	450851.PHZ_c3077	1.635e-57	212.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3628667_1	234267.Acid_5220	8.783e-21	95.0	COG3540@1|root,COG3540@2|Bacteria,3Y3WC@57723|Acidobacteria	57723|Acidobacteria	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
YYD3_k127_3628667_0	1267535.KB906767_gene447	1.125e-153	514.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
YYD3_k127_3643192_0	234267.Acid_5856	2.71e-118	402.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_3645719_12	234267.Acid_4532	4.512e-13	77.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	asp2	-	3.4.11.5	ko:K01259,ko:K06889,ko:K12269	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002,ko02044	3.A.5.10	-	-	Asp2
YYD3_k127_3645719_8	935840.JAEQ01000002_gene3350	5.184e-56	202.0	COG0431@1|root,COG0431@2|Bacteria,1MXQ8@1224|Proteobacteria,2TRI5@28211|Alphaproteobacteria,43RAT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YYD3_k127_3645719_9	2002.JOEQ01000031_gene1648	1.144e-43	161.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
YYD3_k127_3645719_1	1267534.KB906756_gene86	3.614e-229	712.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
YYD3_k127_3645719_13	105422.BBPM01000064_gene541	0.0004103	53.0	COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,2NJUW@228398|Streptacidiphilus	201174|Actinobacteria	H	Methionine biosynthesis protein MetW	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
YYD3_k127_3645719_0	187272.Mlg_0261	7.952e-291	918.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
YYD3_k127_3645719_10	136993.KB900627_gene392	3.267e-27	124.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3645719_5	861299.J421_2040	8.077e-69	241.0	COG0639@1|root,COG0639@2|Bacteria,1ZUFY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YYD3_k127_3645719_11	68194.JNXR01000021_gene859	2.611e-25	110.0	COG1695@1|root,COG1695@2|Bacteria,2GRVH@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_3645719_2	640511.BC1002_4701	5.803e-88	295.0	COG0684@1|root,COG0684@2|Bacteria,1R70C@1224|Proteobacteria,2VPDE@28216|Betaproteobacteria,1K3G1@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
YYD3_k127_3645719_4	264198.Reut_B5774	2.889e-69	241.0	COG0684@1|root,COG0684@2|Bacteria,1QSHP@1224|Proteobacteria,2VJV8@28216|Betaproteobacteria,1K0T1@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
YYD3_k127_3645719_3	392499.Swit_3064	2.968e-84	291.0	COG3384@1|root,COG3384@2|Bacteria,1R6R4@1224|Proteobacteria,2U82Q@28211|Alphaproteobacteria,2K4FE@204457|Sphingomonadales	204457|Sphingomonadales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15061	ko00627,ko01120,map00627,map01120	-	R09276	RC01306	ko00000,ko00001	-	-	-	LigB
YYD3_k127_3645719_6	1122915.AUGY01000118_gene6542	7.103e-67	244.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
YYD3_k127_3645719_7	1121090.KB894689_gene333	3.4e-56	200.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YYD3_k127_365975_0	861299.J421_0835	6.514e-55	205.0	2DQ6W@1|root,3350G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3676513_3	314230.DSM3645_18851	1.483e-21	104.0	2EK8J@1|root,33DYX@2|Bacteria,2J1AU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3676513_0	1210884.HG799464_gene11027	1.672e-157	509.0	COG0635@1|root,COG0635@2|Bacteria,2IY84@203682|Planctomycetes	203682|Planctomycetes	H	COG0635 Coproporphyrinogen III oxidase and related Fe-S	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_3676513_2	1403819.BATR01000130_gene4641	1.419e-22	102.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia,2IUVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
YYD3_k127_3676513_1	1123242.JH636434_gene5534	3.338e-131	431.0	COG1541@1|root,COG1541@2|Bacteria,2IXI4@203682|Planctomycetes	203682|Planctomycetes	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
YYD3_k127_3688223_5	234267.Acid_7916	1.427e-101	357.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
YYD3_k127_3688223_13	1040989.AWZU01000037_gene7291	2.569e-15	85.0	COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2U5M6@28211|Alphaproteobacteria,3JY65@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the globin family	-	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	Globin
YYD3_k127_3688223_9	344747.PM8797T_04090	2.217e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_3688223_7	1267533.KB906733_gene3472	1.076e-69	253.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
YYD3_k127_3688223_10	326297.Sama_3478	4.092e-44	164.0	COG1017@1|root,COG1017@2|Bacteria,1QUQ4@1224|Proteobacteria,1SAA1@1236|Gammaproteobacteria,2QBZG@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the globin family	-	-	1.14.12.17	ko:K05916	ko05132,map05132	-	-	-	ko00000,ko00001,ko01000	-	-	-	Globin
YYD3_k127_3688223_3	234267.Acid_3757	1.272e-157	517.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K03086,ko:K06867,ko:K06886	-	-	-	-	ko00000,ko03021	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_3688223_8	1267534.KB906754_gene3171	1.12e-55	213.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD3_k127_3688223_0	448385.sce0713	0.0	1140.0	COG0642@1|root,COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43ED4@68525|delta/epsilon subdivisions,2X81C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
YYD3_k127_3688223_4	246197.MXAN_2289	4.745e-151	492.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YYD3_k127_3688223_2	1380393.JHVP01000004_gene612	2.363e-213	677.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
YYD3_k127_3688223_6	761193.Runsl_2787	1.695e-76	278.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
YYD3_k127_3688223_12	1125863.JAFN01000001_gene1462	2.7e-17	89.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
YYD3_k127_3688223_14	547043.BIFPSEUDO_03373	2.827e-14	73.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
YYD3_k127_3688223_1	448385.sce8106	2.669e-239	752.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
YYD3_k127_3688223_11	1123236.KB899401_gene2330	7.913e-26	113.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S9EI@1236|Gammaproteobacteria,468HZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
YYD3_k127_369083_3	1125863.JAFN01000001_gene546	6.464e-19	92.0	COG2402@1|root,COG2402@2|Bacteria,1NK19@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_369083_1	391038.Bphy_7286	6.089e-24	115.0	2A7SR@1|root,30WRT@2|Bacteria,1N1R6@1224|Proteobacteria,2W72Y@28216|Betaproteobacteria,1KDNC@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_369083_0	765913.ThidrDRAFT_4524	8.029e-43	173.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	DUF1186,PRiA4_ORF3,SEC-C
YYD3_k127_369083_2	1123252.ATZF01000021_gene2979	1.342e-20	97.0	2E9JR@1|root,333SK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3708564_0	749927.AMED_1253	1.292e-48	181.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4E2R0@85010|Pseudonocardiales	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YYD3_k127_3708564_1	1124983.PFLCHA0_c21940	1.076e-11	77.0	2E0I2@1|root,33KZA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3738615_1	1298867.AUES01000059_gene4749	3.102e-49	190.0	COG4313@1|root,COG4313@2|Bacteria,1PXJ3@1224|Proteobacteria,2UAPJ@28211|Alphaproteobacteria,3K39K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YYD3_k127_3738615_0	234267.Acid_4431	3.001e-199	653.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_3738615_2	1192034.CAP_1554	0.0001032	45.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1554|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3745696_2	324602.Caur_1579	4.122e-19	87.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi,3765Z@32061|Chloroflexia	32061|Chloroflexia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD3_k127_3745696_0	290317.Cpha266_2588	1.506e-180	582.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
YYD3_k127_3745696_1	743718.Isova_0113	2.279e-79	272.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4F4E7@85017|Promicromonosporaceae	201174|Actinobacteria	S	Belongs to the UPF0271 (lamB) family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
YYD3_k127_3761485_8	926566.Terro_0633	1.601e-78	285.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
YYD3_k127_3761485_3	1382359.JIAL01000001_gene136	1.598e-193	629.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
YYD3_k127_3761485_4	234267.Acid_4486	1.269e-179	580.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria	57723|Acidobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
YYD3_k127_3761485_11	187272.Mlg_0267	6.032e-58	211.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YYD3_k127_3761485_19	671143.DAMO_2063	2.963e-26	117.0	COG3824@1|root,COG3824@2|Bacteria,2NPZF@2323|unclassified Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	MA20_43655	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Zincin_1
YYD3_k127_3761485_10	1095767.CAHD01000035_gene1168	4.914e-58	211.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4F0JA@85016|Cellulomonadaceae	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YYD3_k127_3761485_9	1379270.AUXF01000006_gene164	3.03e-72	249.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YYD3_k127_3761485_2	234267.Acid_7763	1.435e-196	634.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YYD3_k127_3761485_15	278963.ATWD01000001_gene4283	5.379e-37	148.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria,2JJDW@204432|Acidobacteriia	204432|Acidobacteriia	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
YYD3_k127_3761485_12	234267.Acid_7275	6.72e-58	211.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria	57723|Acidobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD3_k127_3761485_7	1144275.COCOR_03253	2.436e-99	337.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2YU6F@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_3761485_6	1089553.Tph_c10350	1.998e-133	440.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,42EX2@68295|Thermoanaerobacterales	186801|Clostridia	C	FAD linked oxidase	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD3_k127_3761485_14	1123261.AXDW01000002_gene1683	1.857e-46	188.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1X3KI@135614|Xanthomonadales	135614|Xanthomonadales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
YYD3_k127_3761485_16	521674.Plim_0560	9.286e-36	140.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
YYD3_k127_3761485_21	1267533.KB906735_gene4559	5.323e-16	79.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
YYD3_k127_3761485_20	1267535.KB906767_gene4539	1.118e-19	100.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3761485_0	926569.ANT_03260	1.639e-278	866.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi	200795|Chloroflexi	H	Thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
YYD3_k127_3761485_13	926569.ANT_03270	1.919e-56	202.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi	200795|Chloroflexi	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
YYD3_k127_3761485_5	1382359.JIAL01000001_gene634	1.426e-153	491.0	COG0059@1|root,COG0059@2|Bacteria,3Y34M@57723|Acidobacteria,2JHXD@204432|Acidobacteriia	204432|Acidobacteriia	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
YYD3_k127_3761485_1	595460.RRSWK_04821	3.706e-264	823.0	COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
YYD3_k127_3761485_18	330214.NIDE3327	8.536e-29	119.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_3761485_17	926550.CLDAP_12520	9.05e-31	128.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_3767039_6	298654.FraEuI1c_4079	8.412e-34	139.0	28JDP@1|root,32SV2@2|Bacteria,2IPQY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3767039_8	1123023.JIAI01000003_gene2732	3.027e-14	83.0	COG3751@1|root,COG3751@2|Bacteria	2|Bacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07336,ko:K07394	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
YYD3_k127_3767039_1	1163407.UU7_06023	1.586e-102	342.0	COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,1RUQU@1236|Gammaproteobacteria,1X4NG@135614|Xanthomonadales	135614|Xanthomonadales	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD3_k127_3767039_7	379066.GAU_3597	8.303e-15	78.0	COG4877@1|root,COG4877@2|Bacteria,1ZVAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3767039_5	1254432.SCE1572_17070	6.168e-62	225.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42RAF@68525|delta/epsilon subdivisions,2WN7G@28221|Deltaproteobacteria,2Z09C@29|Myxococcales	28221|Deltaproteobacteria	H	Site-specific DNA-methyltransferase (Adenine-specific)	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
YYD3_k127_3767039_4	204669.Acid345_1561	1.537e-68	250.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia	204432|Acidobacteriia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YYD3_k127_3767039_2	204669.Acid345_1560	6.429e-90	301.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia	204432|Acidobacteriia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YYD3_k127_3767039_0	290397.Adeh_3352	2.836e-172	550.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YYD3_k127_3767039_3	1267535.KB906767_gene3175	4.481e-75	258.0	COG0466@1|root,COG0466@2|Bacteria,3Y3DI@57723|Acidobacteria,2JIB4@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_3770900_1	525897.Dbac_1178	7.831e-102	349.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2M93H@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
YYD3_k127_3770900_4	237368.SCABRO_03229	3.033e-10	70.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Laminin_G_3,PKD,PPC,Phage-tail_3,Reprolysin_3,fn3
YYD3_k127_3770900_3	479433.Caci_7461	1.695e-14	83.0	COG3979@1|root,COG4934@1|root,COG3979@2|Bacteria,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_5_12,Glyco_hydro_18,He_PIG,fn3
YYD3_k127_3770900_5	330214.NIDE1191	8.17e-06	57.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	fn3
YYD3_k127_3770900_0	1198114.AciX9_2892	1.06e-132	453.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD3_k127_3770900_2	1198114.AciX9_2897	4.015e-64	240.0	COG1404@1|root,COG5164@1|root,COG1404@2|Bacteria,COG5164@2|Bacteria,3Y5WB@57723|Acidobacteria,2JK6I@204432|Acidobacteriia	204432|Acidobacteriia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
YYD3_k127_3795543_22	1038862.KB893807_gene2011	1.644e-16	84.0	COG2867@1|root,COG2867@2|Bacteria,1RFKW@1224|Proteobacteria,2U7PF@28211|Alphaproteobacteria,3JZ48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3795543_27	1267535.KB906767_gene1834	2.691e-05	50.0	COG1793@1|root,COG1793@2|Bacteria,3Y2VV@57723|Acidobacteria,2JIJ7@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase D, 3'-phosphoesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
YYD3_k127_3795543_28	936589.HMPREF1521_1482	5.667e-05	50.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4H68X@909932|Negativicutes	909932|Negativicutes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
YYD3_k127_3795543_21	935567.JAES01000002_gene667	1.91e-23	105.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1X7GP@135614|Xanthomonadales	135614|Xanthomonadales	P	protein involved in tolerance to divalent cations	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
YYD3_k127_3795543_11	1121438.JNJA01000007_gene1645	8.859e-72	250.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MATW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YYD3_k127_3795543_5	1242864.D187_006315	1.719e-146	473.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
YYD3_k127_3795543_13	880073.Calab_1892	2.028e-55	218.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
YYD3_k127_3795543_12	1267533.KB906733_gene3234	2.685e-56	209.0	COG0571@1|root,COG0571@2|Bacteria,3Y4M2@57723|Acidobacteria,2JJ95@204432|Acidobacteriia	204432|Acidobacteriia	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YYD3_k127_3795543_15	1340493.JNIF01000004_gene291	6.72e-47	173.0	COG2346@1|root,COG2346@2|Bacteria,3Y8TC@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YYD3_k127_3795543_23	342949.PNA2_0582	3.702e-10	72.0	COG1672@1|root,arCOG03169@2157|Archaea,2Y162@28890|Euryarchaeota,243JN@183968|Thermococci	183968|Thermococci	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2,HTH_24,Mrr_cat
YYD3_k127_3795543_0	941824.TCEL_01674	3.424e-258	806.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,36DK8@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
YYD3_k127_3795543_3	378806.STAUR_3990	4.201e-154	501.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2YUFR@29|Myxococcales	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
YYD3_k127_3795543_6	1009370.ALO_03244	1.684e-143	467.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H24N@909932|Negativicutes	909932|Negativicutes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
YYD3_k127_3795543_10	1254432.SCE1572_33570	1.526e-88	298.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
YYD3_k127_3795543_8	1254432.SCE1572_33565	1.246e-94	321.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
YYD3_k127_3795543_20	1236959.BAMT01000015_gene2849	8.547e-24	110.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3795543_9	290397.Adeh_0784	2.933e-90	310.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
YYD3_k127_3795543_7	518766.Rmar_0538	1.371e-114	377.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
YYD3_k127_3795543_24	1267535.KB906767_gene555	1.022e-09	71.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_2,TonB_C
YYD3_k127_3795543_25	215803.DB30_6626	2.893e-08	66.0	COG0810@1|root,COG0810@2|Bacteria,1PEIS@1224|Proteobacteria,42X2T@68525|delta/epsilon subdivisions,2X03B@28221|Deltaproteobacteria,2YX9S@29|Myxococcales	28221|Deltaproteobacteria	U	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_3795543_17	861299.J421_1974	2.17e-33	147.0	COG3595@1|root,COG4219@1|root,COG3595@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	DUF4097
YYD3_k127_3795543_16	234267.Acid_4815	5.05e-34	134.0	COG3682@1|root,COG3682@2|Bacteria,3Y8BB@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_3795543_14	861299.J421_1503	5.508e-52	190.0	COG2318@1|root,COG2318@2|Bacteria,1ZU0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_3795543_2	1265505.ATUG01000002_gene1318	7.415e-157	507.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,42U9J@68525|delta/epsilon subdivisions,2WQ39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	ko:K05548,ko:K05819,ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
YYD3_k127_3795543_4	1254432.SCE1572_11415	4.212e-153	503.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
YYD3_k127_3795543_1	935840.JAEQ01000018_gene2029	3.059e-242	754.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	-	ko:K15064	ko00627,ko01120,map00627,map01120	-	R09270	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_3795543_19	452637.Oter_0488	2.365e-24	118.0	COG0457@1|root,COG0457@2|Bacteria,46U59@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
YYD3_k127_3797608_1	234267.Acid_5217	1.695e-15	81.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
YYD3_k127_3797608_0	314230.DSM3645_11631	3.033e-56	201.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_380284_3	1121033.AUCF01000003_gene3041	5.109e-60	219.0	COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,2TTXQ@28211|Alphaproteobacteria,2JWHU@204441|Rhodospirillales	204441|Rhodospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YYD3_k127_380284_15	472759.Nhal_1885	5.808e-27	115.0	COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,1X1W5@135613|Chromatiales	135613|Chromatiales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD3_k127_380284_6	323848.Nmul_A1524	3.867e-50	196.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VQ9I@28216|Betaproteobacteria,371PA@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YYD3_k127_380284_2	472759.Nhal_1635	6.892e-136	469.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales	135613|Chromatiales	I	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2,SNARE_assoc
YYD3_k127_380284_14	1095769.CAHF01000006_gene1704	2.809e-27	120.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2VHM3@28216|Betaproteobacteria,4756U@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Phospholipase D Active site motif	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,PLDc_2,SNARE_assoc
YYD3_k127_380284_9	1123277.KB893177_gene3658	1.428e-46	173.0	COG0454@1|root,COG0456@2|Bacteria,4NU6N@976|Bacteroidetes,47VGZ@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_380284_19	269798.CHU_1017	0.0009671	50.0	COG4914@1|root,COG4914@2|Bacteria,4NT8U@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_380284_10	1349785.BAUG01000022_gene1419	2.859e-42	168.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_380284_17	1237149.C900_05483	5.478e-09	61.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
YYD3_k127_380284_11	234267.Acid_5553	3.98e-41	162.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738,Peptidase_M56
YYD3_k127_380284_13	1500894.JQNN01000001_gene80	1.152e-27	125.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2W2VW@28216|Betaproteobacteria,477Q5@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
YYD3_k127_380284_7	234267.Acid_5553	1.071e-47	188.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738,Peptidase_M56
YYD3_k127_380284_16	551789.ATVJ01000001_gene1039	8.601e-11	69.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_380284_8	861299.J421_0835	1.092e-47	183.0	2DQ6W@1|root,3350G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_380284_1	234267.Acid_7730	1.888e-190	601.0	COG1415@1|root,COG1415@2|Bacteria,3Y6D2@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
YYD3_k127_380284_0	234267.Acid_1737	3.096e-227	757.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_380284_5	1095769.CAHF01000006_gene1858	4.518e-53	197.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2VRGI@28216|Betaproteobacteria,477X3@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
YYD3_k127_380284_4	864069.MicloDRAFT_00013860	6.416e-58	204.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2TQPP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
YYD3_k127_380284_12	467200.ACFA01000441_gene1984	8.888e-29	116.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
YYD3_k127_380284_18	398767.Glov_2674	0.0002061	44.0	2CF4Z@1|root,330XB@2|Bacteria,1NIZ5@1224|Proteobacteria,42WR5@68525|delta/epsilon subdivisions,2WS24@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
YYD3_k127_3817080_0	1244869.H261_21124	2.441e-261	823.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria,2JPK6@204441|Rhodospirillales	204441|Rhodospirillales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
YYD3_k127_3817080_2	1254432.SCE1572_20115	7.676e-23	104.0	COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria	1224|Proteobacteria	S	COG0517, FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
YYD3_k127_3817080_1	626887.J057_15510	1.762e-47	180.0	COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria	1224|Proteobacteria	CH	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
YYD3_k127_3817080_3	1009370.ALO_20812	5.793e-11	74.0	COG0810@1|root,COG0810@2|Bacteria,1VDCH@1239|Firmicutes,4H54A@909932|Negativicutes	909932|Negativicutes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_3849978_4	575540.Isop_0300	7.544e-110	368.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
YYD3_k127_3849978_2	1217720.ALOX01000055_gene961	5.728e-125	406.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TRG7@28211|Alphaproteobacteria,2JRQR@204441|Rhodospirillales	204441|Rhodospirillales	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
YYD3_k127_3849978_9	1239415.CM001837_gene1455	3.758e-30	131.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia,37E67@326319|Dokdonia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3849978_0	1340493.JNIF01000003_gene3558	2.297e-269	840.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
YYD3_k127_3849978_10	62928.azo2654	7.236e-23	111.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2VRX6@28216|Betaproteobacteria,2KWX0@206389|Rhodocyclales	206389|Rhodocyclales	S	Glyoxalase-like domain	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_3849978_12	1403819.BATR01000124_gene4382	1.181e-19	101.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_3849978_7	204669.Acid345_3132	2.09e-45	170.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD3_k127_3849978_5	69395.JQLZ01000005_gene3645	2.631e-61	222.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3849978_13	926566.Terro_0097	1.013e-06	52.0	COG2027@1|root,COG2027@2|Bacteria,3Y7ZS@57723|Acidobacteria,2JMZE@204432|Acidobacteriia	204432|Acidobacteriia	M	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
YYD3_k127_3849978_1	1121377.KB906418_gene3766	2.32e-213	698.0	COG3629@1|root,COG3629@2|Bacteria,1WKSF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
YYD3_k127_3849978_11	1123073.KB899242_gene1520	1.87e-20	97.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	4.4.1.3,5.3.3.19	ko:K16953,ko:K19547	ko00920,ko01130,map00920,map01130	M00787	R02574	RC00747,RC00748	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Arg_Hydrox,Cupin_1,Cupin_2
YYD3_k127_3849978_8	1121377.KB906418_gene3765	3.59e-44	167.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7,DUF4437
YYD3_k127_3849978_6	1112217.PPL19_15099	2.543e-60	220.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,1RPXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	yfjR	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
YYD3_k127_3849978_3	196367.JNFG01000008_gene6597	4.779e-120	392.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2VRSG@28216|Betaproteobacteria,1K889@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_3932234_8	330214.NIDE1919	5.256e-35	138.0	COG0621@1|root,COG0621@2|Bacteria,3J0GE@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YYD3_k127_3932234_9	485918.Cpin_2674	1.323e-27	129.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1IV1T@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3932234_6	1122137.AQXF01000001_gene3194	2.88e-48	188.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3932234_4	1007103.AFHW01000025_gene338	2.19e-74	260.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
YYD3_k127_3932234_3	234267.Acid_5036	1.077e-98	351.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
YYD3_k127_3932234_5	1267533.KB906736_gene1246	7.62e-52	208.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_3932234_2	330214.NIDE0474	8.231e-121	397.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
YYD3_k127_3932234_1	330214.NIDE0473	7.442e-126	429.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
YYD3_k127_3932234_0	1550091.JROE01000002_gene587	3.632e-188	626.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes	976|Bacteroidetes	E	TIGRFAM oligoendopeptidase, M3 family	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YYD3_k127_3932234_10	1116369.KB890024_gene3356	1.571e-06	55.0	COG1359@1|root,COG1359@2|Bacteria,1N1I5@1224|Proteobacteria,2UCV3@28211|Alphaproteobacteria,43KYA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YYD3_k127_3932234_7	1267533.KB906733_gene3215	7.616e-36	145.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_3983776_21	1382359.JIAL01000001_gene2930	8.804e-28	118.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria,2JHJ5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD3_k127_3983776_2	555088.DealDRAFT_1815	9.045e-204	645.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42K3N@68298|Syntrophomonadaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
YYD3_k127_3983776_24	1163407.UU7_07826	8.726e-16	88.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3983776_14	1121441.AUCX01000012_gene3309	7.34e-57	208.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2M9RT@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
YYD3_k127_3983776_23	1047013.AQSP01000099_gene1496	6.749e-16	81.0	COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.64,2.C.1.2	-	-	MttA_Hcf106
YYD3_k127_3983776_7	1198114.AciX9_1119	2.921e-112	382.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YYD3_k127_3983776_6	1201292.DR75_1816	2.646e-124	442.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,4B07V@81852|Enterococcaceae	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
YYD3_k127_3983776_27	391623.TERMP_00526	0.0003622	52.0	COG3595@1|root,arCOG03825@2157|Archaea,2XWNU@28890|Euryarchaeota,243I8@183968|Thermococci	183968|Thermococci	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YYD3_k127_3983776_10	204669.Acid345_0572	2.251e-75	268.0	COG0501@1|root,COG0501@2|Bacteria,3Y2PP@57723|Acidobacteria,2JI24@204432|Acidobacteriia	2|Bacteria	O	Peptidase M48	agmM	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
YYD3_k127_3983776_26	1340434.AXVA01000010_gene5266	1.025e-08	61.0	COG4263@1|root,COG4263@2|Bacteria,1UYT4@1239|Firmicutes,4HUEQ@91061|Bacilli,1ZE59@1386|Bacillus	91061|Bacilli	C	Cupredoxin-like domain	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
YYD3_k127_3983776_9	1267533.KB906739_gene2555	9.021e-94	312.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YYD3_k127_3983776_3	234267.Acid_7759	5.757e-158	511.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria	57723|Acidobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YYD3_k127_3983776_16	1278073.MYSTI_02367	4.24e-36	138.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2YVRR@29|Myxococcales	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YYD3_k127_3983776_12	1267535.KB906767_gene2291	7.162e-62	224.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria,2JIGA@204432|Acidobacteriia	204432|Acidobacteriia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
YYD3_k127_3983776_11	204669.Acid345_4214	1.835e-65	239.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
YYD3_k127_3983776_22	338963.Pcar_1557	2.412e-27	116.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42U0Y@68525|delta/epsilon subdivisions,2WR00@28221|Deltaproteobacteria,43V4Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YYD3_k127_3983776_25	1267535.KB906767_gene3291	2.482e-15	79.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
YYD3_k127_3983776_1	1123371.ATXH01000025_gene203	2.771e-206	674.0	COG0532@1|root,COG0532@2|Bacteria,2GGT0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
YYD3_k127_3983776_4	234267.Acid_5180	3.392e-131	429.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YYD3_k127_3983776_19	370438.PTH_1265	1.559e-30	129.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,2629C@186807|Peptococcaceae	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
YYD3_k127_3983776_5	278963.ATWD01000001_gene1650	2.207e-130	432.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
YYD3_k127_3983776_0	886293.Sinac_2422	5.767e-224	702.0	COG0017@1|root,COG0017@2|Bacteria,2IWX6@203682|Planctomycetes	203682|Planctomycetes	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD3_k127_3983776_17	1382359.JIAL01000001_gene1443	1.757e-35	146.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria,2JJ3U@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_3983776_13	706587.Desti_1483	5.326e-61	223.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
YYD3_k127_3983776_18	290397.Adeh_3692	8.031e-34	144.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
YYD3_k127_3983776_20	1267535.KB906767_gene3462	1.273e-29	125.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria	57723|Acidobacteria	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
YYD3_k127_3983776_8	439235.Dalk_3706	4.841e-96	334.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_3983776_15	234267.Acid_4415	1.329e-54	197.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD3_k127_4005607_2	243231.GSU2429	4.083e-54	203.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
YYD3_k127_4005607_4	713587.THITH_13650	9.321e-16	82.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the HSP15 family	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
YYD3_k127_4005607_3	671143.DAMO_2747	4.872e-45	176.0	COG2378@1|root,COG2378@2|Bacteria,2NPY6@2323|unclassified Bacteria	2|Bacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
YYD3_k127_4005607_0	443144.GM21_2279	4.429e-248	797.0	COG1615@1|root,COG1615@2|Bacteria,1MZ5A@1224|Proteobacteria,42M4M@68525|delta/epsilon subdivisions,2WIPI@28221|Deltaproteobacteria,43SU8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
YYD3_k127_4005607_1	945713.IALB_0353	1.079e-75	262.0	COG0101@1|root,COG0101@2|Bacteria	2|Bacteria	J	tRNA pseudouridine synthase activity	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YYD3_k127_4009337_5	661478.OP10G_3256	1.999e-17	93.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	CBM_35,CBM_6,GHL10,Glyco_hydro_66,Polysacc_deac_1,Ricin_B_lectin,SLH
YYD3_k127_4009337_0	85643.Tmz1t_3390	5.834e-161	520.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,2KUBR@206389|Rhodocyclales	206389|Rhodocyclales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YYD3_k127_4009337_2	886293.Sinac_3357	1.228e-148	482.0	COG1252@1|root,COG1252@2|Bacteria,2IXBA@203682|Planctomycetes	203682|Planctomycetes	C	NADH dehydrogenase, FAD-containing subunit	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD3_k127_4009337_1	292459.STH518	2.672e-150	499.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YYD3_k127_4009337_6	1173028.ANKO01000078_gene3878	9.754e-15	76.0	COG3729@1|root,COG3729@2|Bacteria	2|Bacteria	D	General stress protein	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
YYD3_k127_4009337_4	1267535.KB906767_gene71	2.268e-27	114.0	COG2924@1|root,COG2924@2|Bacteria,3Y4ZS@57723|Acidobacteria	57723|Acidobacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
YYD3_k127_4009337_3	1267535.KB906767_gene75	2.014e-119	399.0	COG1181@1|root,COG1181@2|Bacteria,3Y7GI@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
YYD3_k127_4010203_3	765911.Thivi_3902	3.242e-27	125.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1WWRZ@135613|Chromatiales	135613|Chromatiales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
YYD3_k127_4010203_2	626418.bglu_1g07830	2.042e-32	128.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VXF9@28216|Betaproteobacteria,1KAQV@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
YYD3_k127_4010203_0	1095769.CAHF01000022_gene253	8.181e-166	547.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_4010203_1	1267533.KB906733_gene3362	1.394e-86	308.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
YYD3_k127_4010203_4	285535.JOEY01000006_gene8241	5.937e-08	54.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_403403_0	1267535.KB906767_gene1411	2.408e-141	465.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria,2JIKY@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_403403_2	234267.Acid_4216	1.424e-38	158.0	COG4219@1|root,COG4219@2|Bacteria,3Y9A7@57723|Acidobacteria	2|Bacteria	KT	Protein of unknown function (DUF3738)	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
YYD3_k127_403403_3	234267.Acid_3264	6.21e-34	139.0	COG2027@1|root,COG2027@2|Bacteria,3Y83H@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
YYD3_k127_403403_1	935840.JAEQ01000002_gene3420	6.258e-106	352.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	MA20_34345	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_4039288_0	234267.Acid_3938	2.635e-179	594.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4039288_2	706587.Desti_2015	1.227e-67	236.0	COG4122@1|root,COG4122@2|Bacteria,1R4VI@1224|Proteobacteria,42VVN@68525|delta/epsilon subdivisions,2WRTH@28221|Deltaproteobacteria,2MS9X@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
YYD3_k127_4039288_1	234267.Acid_5827	2.765e-72	262.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4042503_5	1144275.COCOR_07165	1.11e-15	90.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,43850@68525|delta/epsilon subdivisions,2WX9Z@28221|Deltaproteobacteria,2YWVT@29|Myxococcales	28221|Deltaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD3_k127_4042503_2	671143.DAMO_1666	1.698e-72	258.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	mauG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
YYD3_k127_4042503_0	234267.Acid_7636	8.709e-165	551.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
YYD3_k127_4042503_3	861299.J421_5849	1.828e-64	238.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YYD3_k127_4042503_1	234267.Acid_3065	4.914e-73	279.0	COG4773@1|root,COG4773@2|Bacteria,3Y9AC@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4042503_6	1535422.ND16A_3553	1.151e-14	83.0	COG3710@1|root,COG3710@2|Bacteria,1R90V@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
YYD3_k127_4042503_7	633147.Olsu_1755	1.483e-12	76.0	COG1716@1|root,COG1716@2|Bacteria,2HUX0@201174|Actinobacteria,4CVX4@84998|Coriobacteriia	84998|Coriobacteriia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
YYD3_k127_4042503_8	234267.Acid_7637	7.591e-08	57.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4043440_2	1267534.KB906754_gene3822	1.888e-51	187.0	COG3832@1|root,COG3832@2|Bacteria,3Y5QW@57723|Acidobacteria	57723|Acidobacteria	K	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD3_k127_4043440_3	240015.ACP_1945	5.105e-43	163.0	COG2318@1|root,COG2318@2|Bacteria,3Y594@57723|Acidobacteria,2JJNR@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_4043440_6	1183438.GKIL_1779	1.293e-17	89.0	COG2272@1|root,COG3187@1|root,COG2272@2|Bacteria,COG3187@2|Bacteria,1GA7U@1117|Cyanobacteria	1117|Cyanobacteria	O	META domain	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	META
YYD3_k127_4043440_5	1090320.KB900605_gene3394	1.564e-19	95.0	COG2940@1|root,COG2940@2|Bacteria,1Q9DE@1224|Proteobacteria,2VDKT@28211|Alphaproteobacteria,2K32C@204457|Sphingomonadales	204457|Sphingomonadales	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YYD3_k127_4043440_0	383372.Rcas_3399	1.111e-139	454.0	COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi,374VZ@32061|Chloroflexia	32061|Chloroflexia	O	PFAM deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YYD3_k127_4043440_4	1267535.KB906767_gene1573	8.542e-27	124.0	COG0760@1|root,COG0760@2|Bacteria,3Y3V9@57723|Acidobacteria,2JICA@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
YYD3_k127_4043440_1	234267.Acid_4407	3.198e-58	207.0	COG3861@1|root,COG3861@2|Bacteria,3Y5WZ@57723|Acidobacteria	57723|Acidobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD3_k127_4050669_9	639030.JHVA01000001_gene3944	1.035e-55	195.0	COG0717@1|root,COG0717@2|Bacteria,3Y42N@57723|Acidobacteria,2JIA0@204432|Acidobacteriia	204432|Acidobacteriia	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
YYD3_k127_4050669_2	926550.CLDAP_00120	6.207e-143	466.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YYD3_k127_4050669_1	653733.Selin_0828	7.852e-200	638.0	COG0173@1|root,COG0173@2|Bacteria	2|Bacteria	J	aspartate-tRNA(Asn) ligase activity	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YYD3_k127_4050669_5	240015.ACP_1700	4.628e-113	375.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria,2JI4V@204432|Acidobacteriia	204432|Acidobacteriia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YYD3_k127_4050669_11	926692.AZYG01000007_gene1276	3.036e-19	94.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WASX@53433|Halanaerobiales	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
YYD3_k127_4050669_8	1121920.AUAU01000006_gene248	2.316e-59	222.0	COG1253@1|root,COG1253@2|Bacteria,3Y3MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YYD3_k127_4050669_7	1449338.JQLU01000004_gene369	9.272e-92	312.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,27FRT@186828|Carnobacteriaceae	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
YYD3_k127_4050669_3	1047013.AQSP01000072_gene988	5.51e-116	388.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	mgtE	GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511	3.6.1.1	ko:K03281,ko:K04767,ko:K06213,ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.26.1,2.A.49	-	iYO844.BSU13300	CBS,MgtE,MgtE_N
YYD3_k127_4050669_10	1340493.JNIF01000003_gene3550	1.3e-20	100.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria	57723|Acidobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
YYD3_k127_4050669_6	469618.FVAG_01564	2.158e-110	364.0	COG0752@1|root,COG0752@2|Bacteria,3786U@32066|Fusobacteria	32066|Fusobacteria	J	Glycyl-tRNA synthetase alpha	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
YYD3_k127_4050669_4	398767.Glov_1022	2.843e-113	392.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
YYD3_k127_4050669_0	452637.Oter_4089	5.09e-234	729.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD3_k127_4051563_0	1278073.MYSTI_05613	1.401e-67	255.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YYD3_k127_4051563_1	1047013.AQSP01000131_gene1841	7.715e-55	220.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4051563_2	1267535.KB906767_gene1622	3.371e-08	58.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_4069912_2	215803.DB30_3263	4.759e-49	178.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
YYD3_k127_4069912_5	653733.Selin_0887	5.029e-37	159.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YYD3_k127_4069912_0	1128421.JAGA01000002_gene140	2.45e-138	452.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
YYD3_k127_4069912_3	525904.Tter_1542	1.669e-41	158.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
YYD3_k127_4069912_1	671143.DAMO_1605	4.753e-70	240.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD3_k127_4069912_4	1232410.KI421424_gene1780	3.705e-37	143.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42UPV@68525|delta/epsilon subdivisions,2WQB6@28221|Deltaproteobacteria,43UXF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YYD3_k127_4076068_3	682795.AciX8_3485	1.212e-61	230.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YYD3_k127_4076068_2	682795.AciX8_3484	8.509e-64	234.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	204432|Acidobacteriia	Q	pfam abc	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD3_k127_4076068_1	682795.AciX8_3483	2.379e-64	234.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YYD3_k127_4076068_5	404380.Gbem_0453	6.935e-05	45.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,432P8@68525|delta/epsilon subdivisions,2WY79@28221|Deltaproteobacteria,43VVH@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4076068_0	879212.DespoDRAFT_00589	6.252e-98	333.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD3_k127_4076068_4	1340493.JNIF01000003_gene3800	3.356e-16	90.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_4076068_6	639030.JHVA01000001_gene1090	0.0002641	50.0	COG2930@1|root,COG2930@2|Bacteria,3Y4GG@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
YYD3_k127_4086904_3	153721.MYP_2017	8.275e-104	344.0	COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
YYD3_k127_4086904_1	926550.CLDAP_00830	1.6e-110	366.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD3_k127_4086904_4	153721.MYP_2019	2.493e-91	314.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,47KZ4@768503|Cytophagia	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD3_k127_4086904_2	279238.Saro_2279	4.19e-110	365.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JZZN@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YYD3_k127_4086904_5	671143.DAMO_1099	2.067e-65	230.0	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU,PhoU_div
YYD3_k127_4086904_7	318586.Pden_1793	4.025e-09	60.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2UJJF@28211|Alphaproteobacteria,2PXTE@265|Paracoccus	28211|Alphaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
YYD3_k127_4086904_0	671143.DAMO_2812	3.504e-209	657.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YYD3_k127_4086904_6	1382359.JIAL01000001_gene1834	2.337e-53	201.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD3_k127_4095685_1	1157637.KB892111_gene4201	7.658e-78	272.0	COG2267@1|root,COG2267@2|Bacteria,2GU81@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4095685_0	1082931.KKY_2582	3.65e-196	628.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_4095685_2	1121448.DGI_0033	6.508e-38	153.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,43BJZ@68525|delta/epsilon subdivisions,2X6XU@28221|Deltaproteobacteria,2MBAK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_4095685_3	204669.Acid345_3936	5.635e-11	65.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_4104535_2	1430440.MGMSRv2_4074	4.161e-101	342.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2JQPT@204441|Rhodospirillales	204441|Rhodospirillales	H	COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase)	cobT	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
YYD3_k127_4104535_3	1122179.KB890418_gene3760	2.742e-64	232.0	COG2937@1|root,COG2937@2|Bacteria,4PPET@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4104535_5	314278.NB231_04047	2.055e-08	60.0	2AI8M@1|root,318P7@2|Bacteria,1PAB9@1224|Proteobacteria	1224|Proteobacteria	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
YYD3_k127_4104535_4	247633.GP2143_17796	1.656e-37	154.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4104535_0	861299.J421_1100	2.381e-129	431.0	COG3391@1|root,COG3391@2|Bacteria,1ZT41@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4104535_1	861299.J421_1106	4.682e-114	383.0	COG2010@1|root,COG2010@2|Bacteria,1ZT07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,HupE_UreJ_2
YYD3_k127_410851_6	1380356.JNIK01000016_gene3654	1.082e-11	68.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,4EWEE@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
YYD3_k127_410851_7	204669.Acid345_2361	2.636e-07	56.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria,2JNW9@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
YYD3_k127_410851_4	555079.Toce_1892	2.921e-30	134.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
YYD3_k127_410851_3	338963.Pcar_1913	1.184e-30	131.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,43UNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YYD3_k127_410851_0	1232410.KI421413_gene499	1.971e-255	815.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43S4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	MutS domain I	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YYD3_k127_410851_1	1499967.BAYZ01000028_gene1281	5.443e-122	409.0	COG0747@1|root,COG0747@2|Bacteria,2NR54@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_410851_8	1089550.ATTH01000001_gene1802	5.074e-06	57.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1FJFK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
YYD3_k127_410851_2	240015.ACP_2871	4.974e-60	211.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria,2JHP2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
YYD3_k127_410851_5	446470.Snas_1505	2.731e-23	101.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YYD3_k127_410851_9	1242864.D187_004469	0.0001348	45.0	29AZZ@1|root,30PVG@2|Bacteria,1Q1Z7@1224|Proteobacteria,434V6@68525|delta/epsilon subdivisions,2WZ6B@28221|Deltaproteobacteria,2Z1F3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_410965_11	234267.Acid_5173	2.155e-18	101.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria	57723|Acidobacteria	T	histidine kinase A domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
YYD3_k127_410965_5	1116472.MGMO_112c00020	1.044e-54	211.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_410965_14	634994.GCWU000323_01463	6.001e-09	68.0	COG4775@1|root,COG4775@2|Bacteria,378TB@32066|Fusobacteria	32066|Fusobacteria	M	Outer membrane protein, OMP85 family	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD3_k127_410965_12	1121127.JAFA01000043_gene4189	2.749e-17	90.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K7R1@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_410965_1	1210884.HG799469_gene14124	2.306e-118	388.0	COG2326@1|root,COG2326@2|Bacteria,2IYWN@203682|Planctomycetes	203682|Planctomycetes	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
YYD3_k127_410965_4	483219.LILAB_28175	4.801e-59	222.0	COG3637@1|root,COG3637@2|Bacteria,1QXUM@1224|Proteobacteria	1224|Proteobacteria	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
YYD3_k127_410965_8	1267535.KB906767_gene4539	3.889e-30	130.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_410965_10	278963.ATWD01000002_gene251	3.45e-19	94.0	COG1413@1|root,COG1413@2|Bacteria,3Y4Z5@57723|Acidobacteria,2JJG6@204432|Acidobacteriia	204432|Acidobacteriia	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
YYD3_k127_410965_0	573.JG24_27235	1.371e-156	509.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF2	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
YYD3_k127_410965_15	225849.swp_3597	2.466e-06	57.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria,2QA0N@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
YYD3_k127_410965_3	639030.JHVA01000001_gene2808	5.194e-72	254.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria,2JM9F@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_410965_7	314278.NB231_07442	3.812e-30	139.0	2E3RZ@1|root,32YPK@2|Bacteria,1NJYT@1224|Proteobacteria,1SHP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_410965_13	926562.Oweho_0029	4.172e-14	82.0	2ATWF@1|root,31JFP@2|Bacteria,4NT3Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_410965_2	247634.GPB2148_1892	2.868e-89	310.0	COG3202@1|root,COG3202@2|Bacteria,1QXXQ@1224|Proteobacteria,1S2KU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TLC ATP/ADP transporter	-	-	-	-	-	-	-	-	-	-	-	-	TLC
YYD3_k127_410965_9	344747.PM8797T_11514	1.731e-25	109.0	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria	2|Bacteria	C	dicarboxylic acid transport	-	-	-	ko:K02030,ko:K11102	-	M00236	-	-	ko00000,ko00002,ko02000	2.A.23.1.1,2.A.23.1.2,3.A.1.3	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,SBP_bac_3,SDF
YYD3_k127_4111162_4	1452536.JARE01000068_gene3684	1.03e-11	71.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
YYD3_k127_4111162_3	1047013.AQSP01000085_gene1984	3.41e-14	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH,Pilin_PilA
YYD3_k127_4111162_0	240015.ACP_0156	1.342e-70	253.0	COG1680@1|root,COG1680@2|Bacteria,3Y3GQ@57723|Acidobacteria,2JII4@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_4111162_2	926554.KI912633_gene3723	3.236e-14	85.0	COG1649@1|root,COG1649@2|Bacteria,1WM1V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
YYD3_k127_4111162_1	63737.Npun_F4684	7.097e-23	102.0	COG2971@1|root,COG2971@2|Bacteria,1G3SA@1117|Cyanobacteria,1HKDJ@1161|Nostocales	1117|Cyanobacteria	G	PFAM BadF BadG BcrA BcrD ATPase family	-	-	2.7.1.59	ko:K00884,ko:K02616	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	BcrAD_BadFG
YYD3_k127_4113328_3	439235.Dalk_2228	2.683e-82	279.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2WJMT@28221|Deltaproteobacteria,2MMV2@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
YYD3_k127_4113328_15	1205680.CAKO01000006_gene3370	3.916e-06	59.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2UH5V@28211|Alphaproteobacteria,2JU5C@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4113328_11	391612.CY0110_28224	2.593e-15	88.0	2DBIE@1|root,32TXH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4113328_13	1123020.AUIE01000003_gene574	6.594e-10	68.0	2CBAE@1|root,32YK1@2|Bacteria,1PT13@1224|Proteobacteria,1TBZI@1236|Gammaproteobacteria,1YJI9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4113328_1	344747.PM8797T_09229	4.128e-101	339.0	COG1595@1|root,COG1595@2|Bacteria,2IYFG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
YYD3_k127_4113328_9	1123008.KB905693_gene1330	6.031e-32	137.0	COG4319@1|root,COG4319@2|Bacteria,4NT6G@976|Bacteroidetes,2FTV9@200643|Bacteroidia,22YRG@171551|Porphyromonadaceae	976|Bacteroidetes	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YYD3_k127_4113328_2	1267535.KB906767_gene1535	1.308e-83	298.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YYD3_k127_4113328_6	1267535.KB906767_gene1533	3.817e-40	157.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K07263	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4113328_4	1123060.JONP01000002_gene1045	1.271e-77	288.0	COG2267@1|root,COG2267@2|Bacteria,1QVG0@1224|Proteobacteria,2TS32@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YYD3_k127_4113328_8	269482.Bcep1808_6278	9.346e-33	147.0	COG2267@1|root,COG2267@2|Bacteria,1QVG0@1224|Proteobacteria,2W2PW@28216|Betaproteobacteria,1KH3M@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YYD3_k127_4113328_14	179408.Osc7112_5105	1.528e-07	55.0	COG0454@1|root,COG0456@2|Bacteria,1G8QC@1117|Cyanobacteria,1HI4S@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YYD3_k127_4113328_5	243090.RB8505	6.797e-71	256.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_4113328_0	234267.Acid_4267	4.81e-152	514.0	COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_4113328_7	204669.Acid345_1284	8.732e-35	136.0	COG1695@1|root,COG1695@2|Bacteria,3Y5C5@57723|Acidobacteria,2JNCX@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_4113328_12	1121920.AUAU01000004_gene817	8.635e-12	67.0	COG0411@1|root,COG0411@2|Bacteria,3Y9E1@57723|Acidobacteria	57723|Acidobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
YYD3_k127_41239_1	1462527.CCDM010000005_gene4965	4.788e-09	59.0	COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,23KVM@182709|Oceanobacillus	91061|Bacilli	M	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
YYD3_k127_4135420_6	1442599.JAAN01000030_gene2064	8.749e-35	136.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
YYD3_k127_4135420_3	1163409.UUA_06759	9.624e-82	287.0	COG4709@1|root,COG4709@2|Bacteria,1NX5K@1224|Proteobacteria,1SPS6@1236|Gammaproteobacteria,1X34I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
YYD3_k127_4135420_9	2880.D7FXH0	1.235e-11	76.0	COG0457@1|root,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_16,TPR_4,TPR_7,TPR_8
YYD3_k127_4135420_7	1384484.AEQU_0518	8.983e-18	88.0	COG1725@1|root,COG1725@2|Bacteria,2HRPU@201174|Actinobacteria,4CVTU@84998|Coriobacteriia	84998|Coriobacteriia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
YYD3_k127_4135420_4	926569.ANT_00090	4.717e-76	265.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	2|Bacteria	O	PFAM band 7 protein	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD3_k127_4135420_8	748247.AZKH_0852	3.179e-12	78.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
YYD3_k127_4135420_1	278963.ATWD01000001_gene2162	1.012e-92	325.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,3Y4B2@57723|Acidobacteria,2JJ4V@204432|Acidobacteriia	204432|Acidobacteriia	M	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
YYD3_k127_4135420_0	1007104.SUS17_2461	1.691e-105	357.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_4135420_2	595460.RRSWK_03108	8.719e-82	283.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_4144416_3	234267.Acid_4895	1.246e-75	265.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4144416_1	485913.Krac_9228	3.396e-90	302.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
YYD3_k127_4144416_2	485913.Krac_9227	7.471e-76	266.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
YYD3_k127_4144416_0	234267.Acid_0085	7.049e-99	332.0	COG1132@1|root,COG1132@2|Bacteria,3Y6PT@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD3_k127_414495_3	1000565.METUNv1_02392	1.056e-152	492.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KYIX@206389|Rhodocyclales	206389|Rhodocyclales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
YYD3_k127_414495_26	247633.GP2143_17801	2.222e-21	99.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_25	1340493.JNIF01000003_gene2123	3.059e-28	126.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_31	345341.KUTG_06184	1.816e-05	57.0	COG0346@1|root,COG0346@2|Bacteria,2IK75@201174|Actinobacteria,4E515@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_414495_12	234267.Acid_4171	1.718e-66	238.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_414495_10	1382356.JQMP01000004_gene339	5.396e-78	271.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,27XEG@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
YYD3_k127_414495_1	29581.BW37_03023	1.043e-168	547.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,478KT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_414495_23	479432.Sros_8760	2.266e-34	149.0	COG0596@1|root,COG0596@2|Bacteria,2HF6I@201174|Actinobacteria,4EQ21@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_22	1283300.ATXB01000002_gene2896	1.254e-34	150.0	COG2020@1|root,COG2020@2|Bacteria,1PK65@1224|Proteobacteria,1TI8M@1236|Gammaproteobacteria,1XGS2@135618|Methylococcales	135618|Methylococcales	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
YYD3_k127_414495_4	1089547.KB913013_gene2073	4.712e-131	438.0	COG1231@1|root,COG1231@2|Bacteria,4NH02@976|Bacteroidetes,47K4V@768503|Cytophagia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YYD3_k127_414495_0	861299.J421_0317	4.785e-292	914.0	28JZZ@1|root,2Z9PZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_21	1121904.ARBP01000018_gene2614	4.646e-35	147.0	COG3675@1|root,COG3675@2|Bacteria	2|Bacteria	I	Lipase (class 3)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
YYD3_k127_414495_8	330214.NIDE0965	1.517e-85	295.0	COG0429@1|root,COG0429@2|Bacteria	2|Bacteria	S	poly(3-hydroxybutyrate) depolymerase activity	-	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
YYD3_k127_414495_14	443143.GM18_0267	1.77e-62	234.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD3_k127_414495_18	1047013.AQSP01000052_gene2599	8.44e-38	158.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD3_k127_414495_11	382464.ABSI01000010_gene3557	2.418e-70	249.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD3_k127_414495_15	204669.Acid345_3047	1.647e-52	196.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,3Y5CC@57723|Acidobacteria,2JHX0@204432|Acidobacteriia	204432|Acidobacteriia	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
YYD3_k127_414495_16	1184267.A11Q_79	6.572e-44	169.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_28	682795.AciX8_2744	6.698e-14	75.0	2CBGA@1|root,32RQS@2|Bacteria,3Y586@57723|Acidobacteria,2JJU2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_13	204669.Acid345_0496	3.371e-64	228.0	COG3568@1|root,COG3568@2|Bacteria,3Y4HM@57723|Acidobacteria,2JKST@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YYD3_k127_414495_7	1340493.JNIF01000003_gene2267	8.893e-96	321.0	2BZ6M@1|root,2Z7HW@2|Bacteria	2|Bacteria	S	InterPro IPR010496	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YYD3_k127_414495_24	945713.IALB_2932	3.499e-30	131.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
YYD3_k127_414495_33	1041147.AUFB01000025_gene6058	5.95e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,2TVRG@28211|Alphaproteobacteria,4B8U9@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD3_k127_414495_17	290397.Adeh_2378	5.972e-38	150.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_414495_2	1047013.AQSP01000115_gene336	6.422e-158	545.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
YYD3_k127_414495_32	1183438.GKIL_4114	4.871e-05	56.0	COG3577@1|root,COG3577@2|Bacteria,1G044@1117|Cyanobacteria	1117|Cyanobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
YYD3_k127_414495_19	234267.Acid_1042	9.482e-37	143.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
YYD3_k127_414495_20	404589.Anae109_4151	5.623e-36	156.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
YYD3_k127_414495_6	1267535.KB906767_gene4061	1.779e-111	382.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_414495_29	1278073.MYSTI_06129	6.958e-13	75.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,42XMG@68525|delta/epsilon subdivisions,2WSJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_414495_27	1134474.O59_000466	2.085e-15	89.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_30	1492737.FEM08_12560	2.031e-10	71.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2NSAQ@237|Flavobacterium	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_414495_9	525904.Tter_0760	1.046e-83	283.0	COG2220@1|root,COG2220@2|Bacteria,2NPQC@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lactamase_B_2,Lactamase_B_3
YYD3_k127_414495_5	1379270.AUXF01000004_gene3127	3.149e-112	377.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YYD3_k127_415705_12	391625.PPSIR1_10825	6.821e-08	57.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
YYD3_k127_415705_3	671143.DAMO_2824	4.903e-90	311.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YYD3_k127_415705_8	1070319.CAGGBEG34_200025	5.108e-15	87.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,1JZQM@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YYD3_k127_415705_10	1210884.HG799462_gene8688	8.892e-14	83.0	COG1595@1|root,COG1595@2|Bacteria,2IZMT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD3_k127_415705_0	204669.Acid345_0224	0.0	1175.0	COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia	204432|Acidobacteriia	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD3_k127_415705_11	1254432.SCE1572_25715	2.886e-08	65.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
YYD3_k127_415705_9	1144275.COCOR_05366	5.355e-14	79.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_415705_5	1278073.MYSTI_05175	3.499e-83	292.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YYD3_k127_415705_4	588932.JHOF01000009_gene676	1.809e-84	300.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_415705_1	251221.35214258	1.709e-97	334.0	COG0612@1|root,COG0612@2|Bacteria,1G1CD@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the peptidase M16 family	pqqE	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_415705_2	1267533.KB906736_gene898	9.336e-92	312.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria,2JI2Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
YYD3_k127_415705_7	323261.Noc_2152	5.993e-18	87.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,1RP9Y@1236|Gammaproteobacteria,1WWGU@135613|Chromatiales	135613|Chromatiales	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	PGPGW,TerC
YYD3_k127_415705_6	743722.Sph21_3960	3.382e-38	154.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
YYD3_k127_417771_2	1210884.HG799466_gene12570	1.233e-106	351.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_417771_0	1267533.KB906735_gene4585	4.794e-294	911.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD3_k127_417771_1	204669.Acid345_1385	5.829e-122	397.0	COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
YYD3_k127_4203708_3	1267534.KB906755_gene4691	2.002e-61	216.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_4203708_2	1267533.KB906733_gene2989	2.508e-62	239.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD3_k127_4203708_9	1303518.CCALI_01833	3.113e-10	69.0	COG1294@1|root,COG1294@2|Bacteria	2|Bacteria	C	oxidative phosphorylation	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120	Cyt_bd_oxida_II
YYD3_k127_4203708_4	1173027.Mic7113_0544	1.698e-38	156.0	2BWMX@1|root,2ZIUW@2|Bacteria,1G304@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4203708_8	1123227.KB899349_gene856	4.392e-13	73.0	COG5470@1|root,COG5470@2|Bacteria,1PJHZ@1224|Proteobacteria,2UDNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
YYD3_k127_4203708_13	211165.AJLN01000050_gene5329	2.322e-06	53.0	2B8UX@1|root,32254@2|Bacteria,1GCTK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4203708_6	1123267.JONN01000001_gene1239	4.093e-28	126.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
YYD3_k127_4203708_0	1123267.JONN01000001_gene1238	1.846e-246	798.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
YYD3_k127_4203708_5	68170.KL590536_gene4988	1.416e-30	130.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E2KG@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4203708_12	159450.NH14_24890	2.213e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,2VWEF@28216|Betaproteobacteria,1K90A@119060|Burkholderiaceae	28216|Betaproteobacteria	T	STAS domain	btrV	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS,STAS_2
YYD3_k127_4203708_11	266779.Meso_2898	2.378e-08	64.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4203708_10	715451.ambt_12010	1.333e-09	68.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4203708_1	234267.Acid_3680	8.392e-86	307.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4203708_7	1552758.NC00_17030	5.906e-25	117.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PYUK@1224|Proteobacteria,1S0VV@1236|Gammaproteobacteria,1X5W9@135614|Xanthomonadales	135614|Xanthomonadales	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
YYD3_k127_4213483_1	234267.Acid_1738	6.682e-213	677.0	COG2373@1|root,COG2373@2|Bacteria,3Y6DW@57723|Acidobacteria	57723|Acidobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
YYD3_k127_4213483_10	1353531.AZNX01000005_gene3358	1.773e-06	51.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,4BACV@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
YYD3_k127_4213483_4	234267.Acid_1958	1.613e-74	266.0	COG1999@1|root,COG1999@2|Bacteria,3Y5CC@57723|Acidobacteria	57723|Acidobacteria	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
YYD3_k127_4213483_0	234267.Acid_1957	7.2e-268	869.0	COG0457@1|root,COG0760@1|root,COG0457@2|Bacteria,COG0760@2|Bacteria,3Y67U@57723|Acidobacteria	57723|Acidobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_4213483_2	1038860.AXAP01000018_gene3108	1.934e-154	528.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_4213483_7	234267.Acid_1337	2.041e-60	218.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
YYD3_k127_4213483_9	1179773.BN6_31150	5.866e-10	63.0	COG1196@1|root,COG1196@2|Bacteria,2GNJ5@201174|Actinobacteria,4E6ZJ@85010|Pseudonocardiales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4213483_3	1267535.KB906767_gene4262	8.427e-117	391.0	COG2271@1|root,COG2271@2|Bacteria,3Y6AJ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_4213483_6	1196324.A374_17599	2.828e-68	256.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli	91061|Bacilli	E	COG3227 Zinc metalloprotease (elastase)	npr	GO:0005575,GO:0005576	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
YYD3_k127_4213483_5	113395.AXAI01000007_gene1414	1.149e-71	258.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,2U1T7@28211|Alphaproteobacteria,3K5X2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_4218264_4	452863.Achl_4588	4.232e-137	453.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria,1WBPX@1268|Micrococcaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
YYD3_k127_4218264_3	1232683.ADIMK_3833	1.151e-139	453.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,465X2@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Ank_4,Glutaminase
YYD3_k127_4218264_0	886293.Sinac_3504	2.241e-189	596.0	COG0667@1|root,COG0667@2|Bacteria,2IXRI@203682|Planctomycetes	203682|Planctomycetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD3_k127_4218264_1	479434.Sthe_3255	2.463e-158	522.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_4218264_6	357808.RoseRS_2504	1.975e-114	386.0	COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,2G5J9@200795|Chloroflexi,377YG@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_4218264_5	1267534.KB906760_gene1427	7.064e-122	413.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_4218264_2	1165096.ARWF01000001_gene1973	1.575e-154	503.0	COG3391@1|root,COG3391@2|Bacteria,1R1UJ@1224|Proteobacteria	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4218264_7	448385.sce1158	1.819e-101	353.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,437VX@68525|delta/epsilon subdivisions,2X35F@28221|Deltaproteobacteria,2YUCR@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_4218264_12	195522.BD01_0726	2.377e-05	55.0	COG0515@1|root,COG3889@1|root,arCOG03264@1|root,arCOG01672@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2Y2TW@28890|Euryarchaeota,243EY@183968|Thermococci	183968|Thermococci	E	solute binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_4218264_9	1121468.AUBR01000033_gene1208	2.745e-61	231.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,42EU1@68295|Thermoanaerobacterales	186801|Clostridia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_4218264_10	485913.Krac_9241	2.689e-56	207.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_4218264_11	861299.J421_2925	1.074e-51	187.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
YYD3_k127_4218264_8	330214.NIDE0204	4.05e-99	333.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
YYD3_k127_4244460_1	395495.Lcho_4019	2.712e-60	214.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2VQ6Y@28216|Betaproteobacteria,1KNHV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4244460_0	502025.Hoch_1577	1.19e-81	298.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_4244460_2	936136.ARRT01000006_gene2115	1.522e-15	91.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BA4K@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_8,Trans_reg_C
YYD3_k127_4316980_3	1340493.JNIF01000004_gene270	9.378e-69	241.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YYD3_k127_4316980_1	1123277.KB893244_gene5040	5.859e-108	371.0	COG1680@1|root,COG1680@2|Bacteria,4NP4H@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_4316980_0	1304883.KI912532_gene2440	1.143e-123	410.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2WGJT@28216|Betaproteobacteria,2KU7W@206389|Rhodocyclales	206389|Rhodocyclales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_4316980_4	234267.Acid_5674	8.542e-45	168.0	2DQPG@1|root,337XC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4316980_2	756272.Plabr_4431	8.719e-78	279.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_4316980_6	204669.Acid345_2284	0.0001095	50.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2
YYD3_k127_4316980_5	886293.Sinac_1154	1.8e-32	129.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_4323348_1	324925.Ppha_0189	4.277e-17	88.0	COG1201@1|root,COG1201@2|Bacteria	2|Bacteria	L	RNA secondary structure unwinding	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
YYD3_k127_4323348_0	266117.Rxyl_1342	1.782e-65	237.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,cNMP_binding
YYD3_k127_4323348_2	396588.Tgr7_0200	1.775e-09	61.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_4330583_0	216591.BCAM2355	3.958e-45	165.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VRD1@28216|Betaproteobacteria,1K7RP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM DGPFAETKE family protein	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_4330583_1	572477.Alvin_3101	2.419e-12	70.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WVXV@135613|Chromatiales	135613|Chromatiales	CP	Na H antiporter	-	-	-	ko:K05559	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
YYD3_k127_4348406_20	697281.Mahau_2527	2.941e-59	220.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,42HXE@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_3,AAA_5,Sigma54_activat
YYD3_k127_4348406_13	518766.Rmar_1973	1.875e-96	323.0	COG1878@1|root,COG1878@2|Bacteria,4PIWM@976|Bacteroidetes,1FJPB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative cyclase	-	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
YYD3_k127_4348406_15	330214.NIDE2960	8.772e-80	287.0	28H5N@1|root,2Z7I8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_7	1403819.BATR01000052_gene1589	3.343e-124	445.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
YYD3_k127_4348406_11	330214.NIDE2957	2.122e-104	370.0	COG0222@1|root,COG0222@2|Bacteria	330214.NIDE2957|-	J	mitochondrial gene expression	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_16	357808.RoseRS_3135	2.759e-77	297.0	COG3540@1|root,COG3540@2|Bacteria,2G9SZ@200795|Chloroflexi	200795|Chloroflexi	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_23	401053.AciPR4_3363	3.397e-48	199.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4348406_29	1047013.AQSP01000100_gene599	3.475e-29	137.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4348406_33	589873.EP13_13630	0.0001205	55.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_27	1279017.AQYJ01000028_gene2525	1.499e-32	146.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_4348406_32	555793.WSK_2321	3.606e-10	69.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_18	204669.Acid345_2891	2.646e-66	235.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD3_k127_4348406_26	234267.Acid_5517	3.134e-38	149.0	COG0657@1|root,COG0657@2|Bacteria,3Y44Z@57723|Acidobacteria	57723|Acidobacteria	I	Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YYD3_k127_4348406_21	1510531.JQJJ01000010_gene2436	2.273e-52	194.0	COG3179@1|root,COG3179@2|Bacteria,1N1NG@1224|Proteobacteria,2VFFN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	to glycosidase Bacteriophage 11b gi 53748214 emb CAH56675.1	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	-
YYD3_k127_4348406_30	136993.KB900627_gene392	3.046e-24	114.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_10	1340493.JNIF01000003_gene3965	9.103e-110	371.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_4348406_6	1340493.JNIF01000003_gene4649	5.529e-145	473.0	COG2010@1|root,COG2041@1|root,COG2010@2|Bacteria,COG2041@2|Bacteria,3Y7UP@57723|Acidobacteria	57723|Acidobacteria	C	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
YYD3_k127_4348406_22	443143.GM18_2800	5.226e-50	184.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2X5P3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
YYD3_k127_4348406_17	1267535.KB906767_gene956	2.296e-66	237.0	COG0596@1|root,COG0596@2|Bacteria,3Y89S@57723|Acidobacteria	57723|Acidobacteria	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_4348406_0	765420.OSCT_2615	0.0	1055.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi,37711@32061|Chloroflexia	32061|Chloroflexia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YYD3_k127_4348406_19	1379270.AUXF01000007_gene863	5.426e-61	215.0	COG4681@1|root,COG4681@2|Bacteria,1ZUJK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YaeQ	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
YYD3_k127_4348406_31	1232410.KI421415_gene3083	2.099e-20	103.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,42TW6@68525|delta/epsilon subdivisions,2WQNT@28221|Deltaproteobacteria,43SNP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Translation initiation factor SUI1	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
YYD3_k127_4348406_3	234267.Acid_3096	1.282e-182	612.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4348406_9	313595.P700755_002664	4.284e-113	376.0	COG0596@1|root,COG0596@2|Bacteria,4NHS0@976|Bacteroidetes,1I5GA@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_4348406_2	1379270.AUXF01000003_gene3645	2.362e-212	674.0	COG2234@1|root,COG2234@2|Bacteria,1ZUHI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD3_k127_4348406_25	1123060.JONP01000024_gene2501	3.397e-45	183.0	COG3473@1|root,COG3473@2|Bacteria,1PMDI@1224|Proteobacteria,2VA40@28211|Alphaproteobacteria,2JYBI@204441|Rhodospirillales	204441|Rhodospirillales	Q	Maleate cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4348406_12	1121022.ABENE_19645	5.089e-104	357.0	COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2U23Q@28211|Alphaproteobacteria,2KHJT@204458|Caulobacterales	204458|Caulobacterales	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_4348406_4	926560.KE387023_gene3737	6.764e-166	527.0	COG3386@1|root,COG3386@2|Bacteria,1WN6C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
YYD3_k127_4348406_28	204669.Acid345_2675	1.108e-29	138.0	COG1629@1|root,COG1629@2|Bacteria,3Y98Z@57723|Acidobacteria,2JI5U@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4348406_5	1121937.AUHJ01000011_gene2889	2.134e-157	505.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
YYD3_k127_4348406_1	682795.AciX8_3013	1.711e-237	744.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria,2JKRT@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_4348406_8	234267.Acid_6138	3.626e-119	406.0	COG0457@1|root,COG2010@1|root,COG0457@2|Bacteria,COG2010@2|Bacteria,3Y67F@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_4348406_14	401053.AciPR4_3363	2.072e-89	328.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4359955_0	1499967.BAYZ01000026_gene1569	2.81e-296	919.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YYD3_k127_4359955_9	204669.Acid345_4766	3.097e-32	130.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD3_k127_4359955_14	1500893.JQNB01000001_gene1494	0.0002372	48.0	2ADS7@1|root,313HQ@2|Bacteria,1QD8F@1224|Proteobacteria,1T95P@1236|Gammaproteobacteria,1XBQB@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4359955_5	518766.Rmar_1955	4.248e-43	168.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1FJ1T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
YYD3_k127_4359955_2	1379270.AUXF01000002_gene1601	1.011e-161	520.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsA	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YYD3_k127_4359955_11	331869.BAL199_21544	4.7e-09	68.0	COG2520@1|root,COG2520@2|Bacteria,1QZ37@1224|Proteobacteria,2TY3P@28211|Alphaproteobacteria,4BTE7@82117|unclassified Alphaproteobacteria	2|Bacteria	J	2OG-Fe(II) oxygenase superfamily	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltransf_31,rRNA_methylase
YYD3_k127_4359955_4	357808.RoseRS_1484	8.272e-120	396.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_4359955_7	1101195.Meth11DRAFT_1447	3.529e-38	157.0	COG0607@1|root,COG3386@1|root,COG0607@2|Bacteria,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VHGN@28216|Betaproteobacteria,2KNEV@206350|Nitrosomonadales	206350|Nitrosomonadales	GP	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
YYD3_k127_4359955_8	234267.Acid_5375	4.224e-35	149.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4359955_13	697282.Mettu_3431	0.0001736	53.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XEHC@135618|Methylococcales	135618|Methylococcales	P	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
YYD3_k127_4359955_1	1038862.KB893873_gene7424	7.591e-167	548.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_4359955_3	234267.Acid_2049	2.243e-122	407.0	COG2010@1|root,COG3828@1|root,COG2010@2|Bacteria,COG3828@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4359955_6	247633.GP2143_17796	1.514e-41	166.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4359955_12	1267534.KB906754_gene3585	4.339e-07	63.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YYD3_k127_4359955_10	682795.AciX8_4581	3.009e-19	103.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria,2JP02@204432|Acidobacteriia	204432|Acidobacteriia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4369635_2	986075.CathTA2_2349	1.662e-108	368.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
YYD3_k127_4369635_3	1382359.JIAL01000001_gene579	2.226e-98	331.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria,2JHUP@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD3_k127_4369635_0	880073.Calab_1758	6.788e-118	390.0	COG3876@1|root,COG3876@2|Bacteria,2NNRQ@2323|unclassified Bacteria	2|Bacteria	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
YYD3_k127_4369635_1	1254432.SCE1572_16030	1.34e-115	385.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
YYD3_k127_4369635_4	1121106.JQKB01000003_gene2502	2.6e-71	253.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2VFQZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_4369635_5	1298863.AUEP01000001_gene743	1.53e-21	96.0	COG1082@1|root,COG1082@2|Bacteria,2GN0M@201174|Actinobacteria,4DRC5@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_4373124_9	1121472.AQWN01000001_gene258	4.455e-65	231.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,26184@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
YYD3_k127_4373124_14	292459.STH2891	1.066e-09	67.0	COG1246@1|root,COG1246@2|Bacteria,1V6TZ@1239|Firmicutes,24KQF@186801|Clostridia	186801|Clostridia	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
YYD3_k127_4373124_3	292459.STH2881	7.568e-103	349.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD3_k127_4373124_11	251229.Chro_4965	3.965e-33	139.0	COG0548@1|root,COG0548@2|Bacteria,1G0R4@1117|Cyanobacteria,3VI6J@52604|Pleurocapsales	1117|Cyanobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argB	AA_kinase
YYD3_k127_4373124_5	649747.HMPREF0083_06031	2.952e-80	281.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,26QA1@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11190	Semialdhyde_dh,Semialdhyde_dhC
YYD3_k127_4373124_12	760568.Desku_1923	2.141e-25	113.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
YYD3_k127_4373124_10	1444309.JAQG01000147_gene995	5.015e-38	159.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,26R4K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
YYD3_k127_4373124_2	283942.IL0616	4.171e-116	393.0	COG0165@1|root,COG1246@1|root,COG0165@2|Bacteria,COG1246@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,2QFCX@267893|Idiomarinaceae	1236|Gammaproteobacteria	E	belongs to the lyase 1 family. Argininosuccinate lyase subfamily	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
YYD3_k127_4373124_15	1267535.KB906767_gene110	1.367e-07	62.0	2DF3Q@1|root,2ZQCR@2|Bacteria,3Y8YJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4373124_4	1382306.JNIM01000001_gene4148	6.214e-85	292.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi	200795|Chloroflexi	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD3_k127_4373124_1	661478.OP10G_0980	1.187e-118	403.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5
YYD3_k127_4373124_7	1304284.L21TH_1757	2.686e-66	250.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,36FNC@31979|Clostridiaceae	186801|Clostridia	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
YYD3_k127_4373124_6	706587.Desti_5385	2.647e-77	275.0	COG2204@1|root,COG3850@1|root,COG2204@2|Bacteria,COG3850@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
YYD3_k127_4373124_0	485913.Krac_7537	2.164e-119	394.0	COG1899@1|root,COG1899@2|Bacteria,2G9B5@200795|Chloroflexi	200795|Chloroflexi	O	Deoxyhypusine synthase	-	-	-	-	-	-	-	-	-	-	-	-	DS
YYD3_k127_4373124_8	717605.Theco_1624	7.677e-66	239.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,26RVP@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
YYD3_k127_4373124_13	1120965.AUBV01000001_gene3331	5.713e-17	91.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,47MIA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YYD3_k127_4404949_2	1366050.N234_28185	2.263e-23	103.0	2A74D@1|root,30W03@2|Bacteria,1RBK6@1224|Proteobacteria,2VYUK@28216|Betaproteobacteria,1KB6H@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4404949_0	1366050.N234_28190	1.955e-219	688.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2VM0R@28216|Betaproteobacteria,1JZY1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
YYD3_k127_4404949_1	1386089.N865_00265	4.179e-95	329.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4FFH2@85021|Intrasporangiaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD3_k127_4404949_3	398527.Bphyt_1692	1.602e-06	51.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria,2WBXP@28216|Betaproteobacteria,1K6VK@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_4406264_2	234267.Acid_5856	3.563e-59	210.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4406264_0	1267533.KB906733_gene3215	9.256e-107	367.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4406264_3	234267.Acid_4721	0.0009684	46.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
YYD3_k127_4406264_1	861299.J421_6359	9.549e-74	269.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_6359|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4409401_2	234267.Acid_6218	1.431e-13	74.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_4409401_1	234267.Acid_2952	3.554e-29	126.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YYD3_k127_4409401_0	401053.AciPR4_3363	3.064e-44	185.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4414457_1	401053.AciPR4_3363	5.597e-35	151.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4414457_0	1267535.KB906767_gene51	2.331e-125	427.0	COG0457@1|root,COG0457@2|Bacteria,3Y67F@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_4453789_14	204669.Acid345_1083	1.679e-36	144.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_4453789_2	477974.Daud_0168	3.227e-232	732.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
YYD3_k127_4453789_15	1907.SGLAU_26435	1.858e-35	141.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
YYD3_k127_4453789_12	522306.CAP2UW1_0011	2.083e-43	162.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
YYD3_k127_4453789_10	243233.MCA2182	4.427e-73	250.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria,1XEGY@135618|Methylococcales	135618|Methylococcales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD3_k127_4453789_7	1267534.KB906756_gene691	5.145e-97	327.0	COG1735@1|root,COG1735@2|Bacteria,3Y646@57723|Acidobacteria	57723|Acidobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4453789_18	1370125.AUWT01000022_gene4441	5.337e-12	72.0	COG5485@1|root,COG5485@2|Bacteria,2GMYI@201174|Actinobacteria,2391A@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD3_k127_4453789_8	234267.Acid_1856	2.097e-80	293.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y45M@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,SpoIIE
YYD3_k127_4453789_16	401053.AciPR4_2577	1.728e-24	106.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_4453789_13	391625.PPSIR1_19754	4.092e-42	158.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2WWZ0@28221|Deltaproteobacteria,2YVD5@29|Myxococcales	28221|Deltaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
YYD3_k127_4453789_1	861299.J421_1457	1.649e-253	796.0	COG2274@1|root,COG2274@2|Bacteria,1ZSX6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD3_k127_4453789_19	338966.Ppro_3114	2.063e-07	63.0	COG2979@1|root,COG2979@2|Bacteria,1R95E@1224|Proteobacteria,42WF3@68525|delta/epsilon subdivisions,2WS14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF533)	-	-	-	-	-	-	-	-	-	-	-	-	DUF533
YYD3_k127_4453789_6	584708.Apau_0783	1.295e-125	411.0	COG2013@1|root,COG2013@2|Bacteria,3TBZZ@508458|Synergistetes	508458|Synergistetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
YYD3_k127_4453789_4	1123508.JH636443_gene5029	6.104e-138	447.0	COG0451@1|root,COG0451@2|Bacteria,2J25C@203682|Planctomycetes	203682|Planctomycetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD3_k127_4453789_3	867900.Celly_0996	9.48e-144	470.0	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4453789_5	414684.RC1_1859	2.853e-131	426.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2JPHC@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_4453789_11	1379698.RBG1_1C00001G0607	9.67e-68	263.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
YYD3_k127_4453789_9	204669.Acid345_1455	9.345e-74	258.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YYD3_k127_4453789_17	40571.JOEA01000014_gene2115	6.599e-13	77.0	COG1595@1|root,COG1595@2|Bacteria,2IEBW@201174|Actinobacteria,4E1R0@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4453789_20	388413.ALPR1_07240	4.623e-05	53.0	COG0454@1|root,COG0456@2|Bacteria,4PMKR@976|Bacteroidetes,47Y42@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_4453789_0	1254432.SCE1572_34940	0.0	1225.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YYD3_k127_4456644_0	234267.Acid_0871	4.259e-41	162.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	234267.Acid_0871|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
YYD3_k127_4456644_3	1313172.YM304_36720	4.178e-05	57.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,RCC1,RCC1_2,VCBS
YYD3_k127_4456644_2	136993.KB900627_gene391	2.255e-18	92.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4456644_1	136993.KB900627_gene392	6.553e-40	158.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4493269_0	1121937.AUHJ01000004_gene1013	1.575e-85	299.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1T7KM@1236|Gammaproteobacteria,46C37@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4523606_0	1382356.JQMP01000004_gene418	3.488e-65	230.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_4523606_1	649349.Lbys_2682	2.247e-16	91.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD3_k127_4587880_0	251221.35211322	2.39e-231	726.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
YYD3_k127_4587880_18	1150599.MPHLEI_06697	3.714e-39	160.0	COG0454@1|root,COG0456@2|Bacteria,2I9PD@201174|Actinobacteria,236TT@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
YYD3_k127_4587880_8	290397.Adeh_0431	1.408e-111	365.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2Z364@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YYD3_k127_4587880_27	1122947.FR7_0396	2.418e-07	63.0	COG0727@1|root,COG0727@2|Bacteria,1U20W@1239|Firmicutes,4H3W0@909932|Negativicutes	909932|Negativicutes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
YYD3_k127_4587880_6	1267533.KB906738_gene2031	2.764e-124	404.0	COG1398@1|root,COG1398@2|Bacteria,3Y3F9@57723|Acidobacteria,2JHWH@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
YYD3_k127_4587880_12	1267533.KB906737_gene1615	1.239e-88	301.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria,2JI6C@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
YYD3_k127_4587880_11	204669.Acid345_4168	2.517e-90	308.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria,2JJ3P@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_4587880_5	1267535.KB906767_gene917	1.486e-141	460.0	COG1915@1|root,COG1915@2|Bacteria,3Y6MM@57723|Acidobacteria	57723|Acidobacteria	S	LOR/SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
YYD3_k127_4587880_7	1242864.D187_005106	4.044e-115	386.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,42M1Z@68525|delta/epsilon subdivisions,2WJYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
YYD3_k127_4587880_13	745411.B3C1_11654	8.484e-88	300.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1J4K1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YYD3_k127_4587880_20	926550.CLDAP_00470	5.586e-20	97.0	COG2897@1|root,COG2897@2|Bacteria,2G6J9@200795|Chloroflexi	200795|Chloroflexi	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YYD3_k127_4587880_14	518766.Rmar_0188	8.963e-71	246.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes	976|Bacteroidetes	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YYD3_k127_4587880_17	1121957.ATVL01000006_gene3178	7.058e-46	181.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807,DUF4097,PA14
YYD3_k127_4587880_3	379066.GAU_0132	2.538e-176	565.0	COG0624@1|root,COG0624@2|Bacteria,1ZUK4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YYD3_k127_4587880_2	861299.J421_1661	3.507e-187	596.0	COG0534@1|root,COG0534@2|Bacteria,1ZUGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
YYD3_k127_4587880_25	1232410.KI421422_gene2024	1.815e-09	68.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria,43VFU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YYD3_k127_4587880_9	251221.35213084	2.508e-104	342.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria	1117|Cyanobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YYD3_k127_4587880_16	693977.Deipr_1137	6.594e-47	181.0	COG0564@1|root,COG0564@2|Bacteria,1WI0R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD3_k127_4587880_10	1121104.AQXH01000001_gene1380	3.382e-98	349.0	COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1IPUD@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YYD3_k127_4587880_4	1279017.AQYJ01000020_gene1324	4.246e-149	487.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	alkaline phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
YYD3_k127_4587880_19	595536.ADVE02000001_gene2974	1.119e-35	140.0	COG2059@1|root,COG2059@2|Bacteria,1RCDP@1224|Proteobacteria,2U6CH@28211|Alphaproteobacteria,36ZMY@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
YYD3_k127_4587880_22	622637.KE124774_gene430	9.48e-16	89.0	COG2059@1|root,COG2059@2|Bacteria,1RGZC@1224|Proteobacteria,2UBKX@28211|Alphaproteobacteria,36ZY4@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
YYD3_k127_4587880_28	551789.ATVJ01000003_gene20	0.0007324	51.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Cellulase
YYD3_k127_4587880_24	1541065.JRFE01000023_gene3846	5.857e-12	70.0	2CCSR@1|root,32RWC@2|Bacteria,1G749@1117|Cyanobacteria,3VMR6@52604|Pleurocapsales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YYD3_k127_4587880_26	234267.Acid_7377	3.072e-09	71.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4587880_15	403833.Pmob_1588	2.242e-63	242.0	COG0065@1|root,COG0065@2|Bacteria,2GDYG@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YYD3_k127_4587880_21	1123325.JHUV01000009_gene410	3.604e-17	96.0	COG0066@1|root,COG0066@2|Bacteria,2G405@200783|Aquificae	200783|Aquificae	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
YYD3_k127_4587880_1	326427.Cagg_3471	1.069e-207	668.0	COG0855@1|root,COG0855@2|Bacteria,2G68J@200795|Chloroflexi,374Y0@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
YYD3_k127_4590721_13	234267.Acid_0464	8.708e-75	260.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
YYD3_k127_4590721_2	1267535.KB906767_gene3120	4.172e-237	743.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria,2JIEV@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
YYD3_k127_4590721_17	234267.Acid_0462	1.289e-19	96.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
YYD3_k127_4590721_14	338963.Pcar_3138	1.166e-70	248.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43S4I@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
YYD3_k127_4590721_10	1120971.AUCA01000041_gene2430	3.483e-86	293.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,278T5@186823|Alicyclobacillaceae	91061|Bacilli	D	Cellulose biosynthesis protein BcsQ	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
YYD3_k127_4590721_18	349520.PPE_04946	2.944e-19	97.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,26QDI@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
YYD3_k127_4590721_4	240015.ACP_2349	2.84e-194	624.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
YYD3_k127_4590721_9	278963.ATWD01000001_gene3154	1.809e-95	332.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
YYD3_k127_4590721_16	1514668.JOOA01000002_gene2603	3.374e-20	96.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
YYD3_k127_4590721_11	1047013.AQSP01000133_gene2153	1.732e-84	301.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
YYD3_k127_4590721_15	317619.ANKN01000004_gene819	1.089e-21	100.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1MMQT@1212|Prochloraceae	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
YYD3_k127_4590721_19	1192034.CAP_5531	7.335e-13	76.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2YVYX@29|Myxococcales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
YYD3_k127_4590721_20	937777.Deipe_2584	1.04e-12	70.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
YYD3_k127_4590721_6	671143.DAMO_0001	1.911e-148	484.0	COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
YYD3_k127_4590721_12	1047013.AQSP01000115_gene338	5.585e-82	286.0	COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria	2|Bacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
YYD3_k127_4590721_0	1232410.KI421422_gene2032	1.477e-301	947.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YYD3_k127_4590721_5	316067.Geob_0005	8.121e-172	548.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,43T5S@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YYD3_k127_4590721_8	1379698.RBG1_1C00001G0278	1.696e-134	439.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
YYD3_k127_4590721_3	635013.TherJR_0848	1.175e-199	646.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YYD3_k127_4590721_1	1267535.KB906767_gene2550	1.38e-251	789.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YYD3_k127_4590721_7	429009.Adeg_2079	1.311e-135	445.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,42ERJ@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
YYD3_k127_4603949_6	1123487.KB892865_gene1426	1.451e-09	66.0	COG1746@1|root,COG1746@2|Bacteria,1RKKB@1224|Proteobacteria,2W31C@28216|Betaproteobacteria	28216|Betaproteobacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4603949_0	1123508.JH636440_gene2608	1.089e-135	459.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
YYD3_k127_4603949_2	857087.Metme_4431	2.349e-75	280.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,1RZAF@1236|Gammaproteobacteria,1XFZE@135618|Methylococcales	1236|Gammaproteobacteria	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_2,PAS_4,PAS_9
YYD3_k127_4603949_3	1268622.AVS7_03080	6.61e-39	160.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9,Response_reg
YYD3_k127_4603949_1	68219.JNXI01000002_gene3959	6.394e-77	268.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4603949_4	278963.ATWD01000001_gene3336	1.001e-18	96.0	COG1629@1|root,COG1629@2|Bacteria,3Y3KT@57723|Acidobacteria,2JI2M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4603949_7	1123393.KB891316_gene1274	3.998e-09	60.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,1KSIR@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
YYD3_k127_4619186_0	1173026.Glo7428_3943	1.526e-145	477.0	COG0737@1|root,COG2931@1|root,COG3391@1|root,COG0737@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0YK@1117|Cyanobacteria	1117|Cyanobacteria	K	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CHRD,DUF4114,DUF4214,Exo_endo_phos,Phytase-like,W_rich_C
YYD3_k127_4625938_12	251221.35214881	0.0003256	53.0	COG2227@1|root,COG2227@2|Bacteria,1G3EJ@1117|Cyanobacteria	1117|Cyanobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
YYD3_k127_4625938_13	1035308.AQYY01000002_gene718	0.0003434	53.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
YYD3_k127_4625938_11	1202532.FF52_07869	5.507e-07	63.0	COG0381@1|root,COG0381@2|Bacteria,4P4KA@976|Bacteroidetes,1I9GS@117743|Flavobacteriia,2P0JI@237|Flavobacterium	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	MGDG_synth
YYD3_k127_4625938_6	402881.Plav_3316	1.223e-69	245.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2U0EC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
YYD3_k127_4625938_8	402881.Plav_3318	2.368e-52	203.0	COG4106@1|root,COG4106@2|Bacteria,1R02P@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_4625938_3	313606.M23134_03651	3.709e-79	270.0	COG0224@1|root,COG0224@2|Bacteria,4PKME@976|Bacteroidetes,47XWH@768503|Cytophagia	976|Bacteroidetes	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
YYD3_k127_4625938_1	384676.PSEEN5370	3.267e-98	331.0	COG1216@1|root,COG1216@2|Bacteria,1NC70@1224|Proteobacteria,1T49B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K13670	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
YYD3_k127_4625938_7	93220.LV28_04950	7.865e-53	206.0	COG4106@1|root,COG4106@2|Bacteria,1QVY9@1224|Proteobacteria,2VYG7@28216|Betaproteobacteria,1KAFS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_4625938_4	1123072.AUDH01000005_gene1668	1.673e-78	267.0	COG0110@1|root,COG0110@2|Bacteria,1RAKB@1224|Proteobacteria,2U3JX@28211|Alphaproteobacteria,2JXAW@204441|Rhodospirillales	204441|Rhodospirillales	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YYD3_k127_4625938_2	1380350.JIAP01000002_gene4585	1.958e-85	303.0	COG1621@1|root,COG1621@2|Bacteria,1N5AZ@1224|Proteobacteria,2U950@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4625938_0	85643.Tmz1t_3256	1.834e-156	503.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,2KY11@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_4625938_9	304371.MCP_1936	2.57e-46	183.0	COG1682@1|root,arCOG04339@2157|Archaea,2Y2VQ@28890|Euryarchaeota,2NA8H@224756|Methanomicrobia	224756|Methanomicrobia	P	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
YYD3_k127_4625938_5	452637.Oter_2770	1.128e-75	269.0	COG1134@1|root,COG1134@2|Bacteria,46SDX@74201|Verrucomicrobia,3K8QN@414999|Opitutae	2|Bacteria	GM	ABC transporter	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
YYD3_k127_4625938_10	234267.Acid_6847	7.016e-27	112.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4641473_1	1288494.EBAPG3_16540	1.058e-224	696.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2VKCP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
YYD3_k127_4641473_3	313589.JNB_18898	2.57e-64	223.0	COG3157@1|root,COG3157@2|Bacteria,2IP19@201174|Actinobacteria,4FI68@85021|Intrasporangiaceae	201174|Actinobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
YYD3_k127_4641473_5	1288494.EBAPG3_16520	1.938e-49	185.0	COG3157@1|root,COG3157@2|Bacteria,1N3Z0@1224|Proteobacteria,2VURN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
YYD3_k127_4641473_2	1288494.EBAPG3_16510	5.307e-110	362.0	COG4455@1|root,COG4455@2|Bacteria,1MWHI@1224|Proteobacteria,2VKHG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Virulence protein SciE type	-	-	-	ko:K11898	-	-	-	-	ko00000,ko02044	-	-	-	ImpE
YYD3_k127_4641473_4	1288494.EBAPG3_16500	6.925e-52	189.0	COG3518@1|root,COG3518@2|Bacteria,1RF51@1224|Proteobacteria,2VRQP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM type VI secretion system lysozyme-related protein	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
YYD3_k127_4641473_0	1288494.EBAPG3_16490	1.622e-255	803.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2VHXS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Type VI secretion protein	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
YYD3_k127_4641473_6	765913.ThidrDRAFT_2287	7.984e-43	161.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RRTG@1236|Gammaproteobacteria,1WY56@135613|Chromatiales	135613|Chromatiales	S	Pfam:T6SS_VasB	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
YYD3_k127_4658216_9	234267.Acid_4535	3.777e-15	75.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
YYD3_k127_4658216_4	404589.Anae109_3720	2.437e-93	316.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,430CM@68525|delta/epsilon subdivisions,2WVWF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
YYD3_k127_4658216_3	1230476.C207_01213	1.367e-98	334.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YYD3_k127_4658216_6	526225.Gobs_1984	3.915e-44	164.0	2E083@1|root,32VVX@2|Bacteria,2IRF7@201174|Actinobacteria,4EW0U@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4658216_8	861299.J421_5888	1.65e-26	115.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	yozG	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
YYD3_k127_4658216_5	861299.J421_5889	6.518e-48	178.0	2DSP1@1|root,33GVU@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
YYD3_k127_4658216_1	1349767.GJA_4075	3.267e-217	698.0	COG4206@1|root,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,2VJZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YYD3_k127_4658216_7	1267535.KB906767_gene5106	8.35e-37	141.0	COG1695@1|root,COG1695@2|Bacteria,3Y7YK@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_4658216_2	234267.Acid_3786	4.282e-196	647.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_4658216_0	1267535.KB906767_gene1122	1.143e-268	857.0	COG0577@1|root,COG0577@2|Bacteria,3Y3YE@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_4660954_1	1047013.AQSP01000088_gene1631	6.973e-139	478.0	COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria	2|Bacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4660954_0	1047013.AQSP01000088_gene1631	1.75e-153	522.0	COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria	2|Bacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4660954_2	903818.KI912268_gene2181	2.934e-74	283.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4660954_3	1121920.AUAU01000028_gene1372	1.958e-62	242.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4661132_1	1313172.YM304_06320	6.255e-07	53.0	2DCWG@1|root,2ZFKS@2|Bacteria	2|Bacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
YYD3_k127_4661132_0	1267535.KB906767_gene3727	5.415e-100	333.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
YYD3_k127_4661913_0	903818.KI912268_gene2181	5.546e-63	246.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_4670461_1	1267534.KB906754_gene3106	3.579e-53	206.0	COG1228@1|root,COG1228@2|Bacteria,3Y539@57723|Acidobacteria,2JKT2@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_4670461_2	748247.AZKH_p0116	5.928e-50	182.0	COG3631@1|root,COG3631@2|Bacteria,1PT2G@1224|Proteobacteria,2WA86@28216|Betaproteobacteria,2KYWR@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
YYD3_k127_4670461_3	1463895.JODA01000033_gene3098	5.003e-10	73.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD3_k127_4670461_5	593117.TGAM_1504	5.551e-08	66.0	arCOG02559@1|root,arCOG03264@1|root,arCOG06661@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG06661@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	28890|Euryarchaeota	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA,Pkinase
YYD3_k127_4670461_0	251229.Chro_2746	2.068e-105	348.0	COG0668@1|root,COG0668@2|Bacteria,1GHVY@1117|Cyanobacteria,3VN2Q@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
YYD3_k127_4670461_4	671143.DAMO_2720	1.61e-08	61.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_4670461_6	1123389.ATXJ01000032_gene1671	1.469e-06	53.0	COG4118@1|root,COG4118@2|Bacteria,1WKUE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YYD3_k127_4670461_7	1487953.JMKF01000083_gene4288	3.043e-06	49.0	2E90H@1|root,3339X@2|Bacteria,1G9EW@1117|Cyanobacteria,1HD02@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4674429_9	316067.Geob_0916	1.994e-07	54.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,43TI0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
YYD3_k127_4674429_6	204669.Acid345_4502	5.459e-49	179.0	COG1490@1|root,COG1490@2|Bacteria,3Y552@57723|Acidobacteria,2JN5I@204432|Acidobacteriia	204432|Acidobacteriia	J	D-Tyr-tRNA(Tyr) deacylase	-	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YYD3_k127_4674429_8	1379698.RBG1_1C00001G0758	3.207e-14	83.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4674429_7	477974.Daud_1604	6.112e-48	192.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YYD3_k127_4674429_5	997346.HMPREF9374_0121	8.802e-52	191.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,27AYG@186824|Thermoactinomycetaceae	91061|Bacilli	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
YYD3_k127_4674429_2	204669.Acid345_2031	1.263e-109	368.0	COG1641@1|root,COG1641@2|Bacteria,3Y42R@57723|Acidobacteria,2JI6G@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
YYD3_k127_4674429_1	935948.KE386494_gene829	9.41e-188	608.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
YYD3_k127_4674429_4	562970.Btus_0052	9.282e-66	233.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,27859@186823|Alicyclobacillaceae	91061|Bacilli	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
YYD3_k127_4674429_3	1125863.JAFN01000001_gene236	8.568e-84	289.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
YYD3_k127_4674429_0	696369.KI912183_gene243	1.256e-196	636.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,260BN@186807|Peptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YYD3_k127_4689095_14	1321773.HMPREF9069_00547	4.284e-18	83.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia	84998|Coriobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD3_k127_4689095_0	243231.GSU2860	4.367e-319	990.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_4689095_9	1460635.JCM19038_3389	2.95e-64	224.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YYD3_k127_4689095_10	404589.Anae109_1907	6.389e-63	218.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2YV8E@29|Myxococcales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YYD3_k127_4689095_7	234267.Acid_6208	1.068e-122	411.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_B
YYD3_k127_4689095_13	234267.Acid_6209	1.787e-27	117.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
YYD3_k127_4689095_4	234267.Acid_4983	5.031e-178	575.0	COG1620@1|root,COG1620@2|Bacteria,3Y2ZA@57723|Acidobacteria	57723|Acidobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
YYD3_k127_4689095_6	1128421.JAGA01000002_gene1223	2.988e-141	461.0	COG0247@1|root,COG0247@2|Bacteria,2NNU8@2323|unclassified Bacteria	2|Bacteria	C	Cysteine-rich domain	glcF	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	iAPECO1_1312.glcF,iECABU_c1320.ECABU_c33760,iECIAI1_1343.ECIAI1_3119,iECIAI39_1322.ECIAI39_3465,iECNA114_1301.ECNA114_3053,iECP_1309.ECP_3055,iJN678.glcF,iJN746.PP_3747,iUTI89_1310.glcF,ic_1306.glcF	CCG,Fer4_7,Fer4_8
YYD3_k127_4689095_8	266117.Rxyl_2832	9.096e-74	263.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CRXQ@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD3_k127_4689095_2	525904.Tter_0160	2.465e-194	617.0	COG0277@1|root,COG0277@2|Bacteria,2NP2P@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750	FAD-oxidase_C,FAD_binding_4
YYD3_k127_4689095_5	526225.Gobs_1559	9.152e-152	491.0	COG3875@1|root,COG3875@2|Bacteria,2I9JU@201174|Actinobacteria,4EUE9@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
YYD3_k127_4689095_15	218284.CCDN010000001_gene445	7.904e-12	78.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
YYD3_k127_4689095_1	234267.Acid_1245	2.695e-200	635.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YYD3_k127_4689095_11	1123377.AUIV01000009_gene2578	1.163e-44	166.0	COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,1S9ZW@1236|Gammaproteobacteria,1X7QK@135614|Xanthomonadales	135614|Xanthomonadales	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
YYD3_k127_4689095_12	243090.RB8171	1.165e-44	172.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_4689095_3	1173028.ANKO01000020_gene5535	3.838e-183	587.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,1HH6G@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
YYD3_k127_4744755_0	1082931.KKY_2582	6.181e-215	679.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_4744755_3	1192034.CAP_3738	1.923e-05	57.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3738|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4744755_2	1283283.ATXA01000001_gene604	5.741e-06	58.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4ETKR@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
YYD3_k127_4744755_1	861299.J421_2723	4.722e-14	84.0	COG3258@1|root,COG4993@1|root,COG3258@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.9.1,1.8.2.2	ko:K02030,ko:K17760,ko:K19713	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	Cytochrom_C,Cytochrome_CBB3,PA14,PQQ,PQQ_2,PSCyt3,PSD3,PSD4,PSD5,SBP_bac_3
YYD3_k127_4795528_1	671143.DAMO_1133	6.031e-30	132.0	COG3746@1|root,COG3746@2|Bacteria,2NRQ1@2323|unclassified Bacteria	2|Bacteria	P	phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
YYD3_k127_4795528_0	234267.Acid_4037	2.791e-62	226.0	COG1502@1|root,COG1502@2|Bacteria,3Y5UA@57723|Acidobacteria	57723|Acidobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
YYD3_k127_4795528_2	583355.Caka_3112	3.078e-14	85.0	COG1285@1|root,COG1285@2|Bacteria,46VKA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
YYD3_k127_4795528_3	1047013.AQSP01000106_gene1763	1.416e-06	61.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_481429_0	1385935.N836_14010	1.428e-95	329.0	COG0793@1|root,COG0793@2|Bacteria,1G3PU@1117|Cyanobacteria,1HE19@1150|Oscillatoriales	1117|Cyanobacteria	E	Periplasmic protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
YYD3_k127_4819959_12	1123060.JONP01000028_gene3680	0.0008193	51.0	COG0346@1|root,COG0346@2|Bacteria,1PK3Q@1224|Proteobacteria,2U2PI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_4819959_3	1267534.KB906756_gene127	2.215e-87	298.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
YYD3_k127_4819959_9	143224.JQMD01000002_gene2686	8.875e-18	100.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,1HYHS@117743|Flavobacteriia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
YYD3_k127_4819959_1	234267.Acid_6439	8.498e-150	528.0	COG1752@1|root,COG1752@2|Bacteria,3Y6N9@57723|Acidobacteria	57723|Acidobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
YYD3_k127_4819959_4	1144275.COCOR_00018	1.03e-78	277.0	COG2267@1|root,COG2267@2|Bacteria,1MZG8@1224|Proteobacteria,42P0T@68525|delta/epsilon subdivisions,2WJ45@28221|Deltaproteobacteria,2YU6Y@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_4819959_7	243231.GSU1762	7.036e-33	141.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
YYD3_k127_4819959_5	861299.J421_6033	1.118e-70	250.0	COG3324@1|root,COG3324@2|Bacteria,1ZU3H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_4819959_11	1335760.ASTG01000003_gene1494	2.59e-05	53.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4819959_6	1297742.A176_06689	1.218e-56	210.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,439F3@68525|delta/epsilon subdivisions,2X4QF@28221|Deltaproteobacteria,2YZE7@29|Myxococcales	28221|Deltaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_4819959_0	1218084.BBJK01000007_gene1059	2e-323	995.0	COG3408@1|root,COG3408@2|Bacteria,1QUN2@1224|Proteobacteria,2WHH3@28216|Betaproteobacteria,1KIP3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
YYD3_k127_4880369_1	1288494.EBAPG3_10120	3.675e-229	717.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,372CG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
YYD3_k127_4880369_3	1123228.AUIH01000064_gene3039	8.951e-55	199.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1XIH1@135619|Oceanospirillales	135619|Oceanospirillales	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YYD3_k127_4880369_4	1379698.RBG1_1C00001G0328	8.556e-50	181.0	2C7E0@1|root,330TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4880369_5	335541.Swol_1671	6.033e-46	171.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YYD3_k127_4880369_2	1144275.COCOR_07655	6.337e-226	717.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
YYD3_k127_4880369_8	717605.Theco_1191	0.000122	53.0	COG5459@1|root,COG5459@2|Bacteria,1V30U@1239|Firmicutes	1239|Firmicutes	J	ribosomal	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
YYD3_k127_4880369_7	240015.ACP_0992	5.276e-11	76.0	COG0457@1|root,COG0457@2|Bacteria	240015.ACP_0992|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4880369_6	710111.FraQA3DRAFT_1524	1.519e-14	80.0	2EHX5@1|root,33BNR@2|Bacteria,2GPW7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4880369_0	1192034.CAP_0838	1.339e-260	811.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YYD3_k127_4891810_0	1123355.JHYO01000017_gene3564	2.197e-192	613.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,36X8C@31993|Methylocystaceae	28211|Alphaproteobacteria	IQ	Phosphate acyltransferases	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
YYD3_k127_4891810_1	1267533.KB906733_gene3215	6.604e-98	344.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4891810_2	1267535.KB906767_gene3433	8.058e-25	106.0	COG1595@1|root,COG1595@2|Bacteria,3Y8YQ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4913522_1	1313301.AUGC01000001_gene1639	3.84e-22	108.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
YYD3_k127_4913522_3	243233.MCA1686	1.271e-12	72.0	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,1SBPJ@1236|Gammaproteobacteria,1XGYD@135618|Methylococcales	135618|Methylococcales	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_4913522_0	204669.Acid345_1027	3.438e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria,2JJAJ@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4913522_2	1380394.JADL01000003_gene5194	4.746e-17	84.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,2JPEE@204441|Rhodospirillales	204441|Rhodospirillales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD3_k127_4924604_13	29540.C481_13209	7.739e-07	60.0	COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,23RZ5@183963|Halobacteria	183963|Halobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
YYD3_k127_4924604_7	1125863.JAFN01000001_gene358	1.702e-46	180.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
YYD3_k127_4924604_1	56780.SYN_02850	5.783e-105	349.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MQCF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YYD3_k127_4924604_6	635013.TherJR_1827	3.447e-63	226.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,261JP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YYD3_k127_4924604_8	289376.THEYE_A2098	7.541e-31	129.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD3_k127_4924604_11	1382356.JQMP01000003_gene2104	1.115e-14	88.0	COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia	189775|Thermomicrobia	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
YYD3_k127_4924604_4	234267.Acid_3974	2.578e-77	270.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria	57723|Acidobacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
YYD3_k127_4924604_15	401053.AciPR4_0456	5.907e-05	49.0	arCOG13401@1|root,33MMV@2|Bacteria,3Y5TE@57723|Acidobacteria,2JNR5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
YYD3_k127_4924604_12	1183438.GKIL_1127	9.955e-10	68.0	COG0745@1|root,COG0745@2|Bacteria,1G2ME@1117|Cyanobacteria	1117|Cyanobacteria	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_4924604_14	404589.Anae109_1523	5.335e-06	57.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,PilZ
YYD3_k127_4924604_0	314345.SPV1_10496	1.697e-175	573.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria	1224|Proteobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
YYD3_k127_4924604_9	635013.TherJR_0443	2.467e-28	116.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,262M2@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory protein, arsR family	cadC	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
YYD3_k127_4924604_2	1499967.BAYZ01000095_gene4170	1.184e-99	334.0	COG1131@1|root,COG1131@2|Bacteria,2NNKB@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ccmA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
YYD3_k127_4924604_5	234267.Acid_4516	3.301e-70	246.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
YYD3_k127_4924604_3	1499967.BAYZ01000095_gene4168	2.665e-79	288.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
YYD3_k127_4924604_10	1195236.CTER_4182	2e-18	98.0	2E8G1@1|root,332UC@2|Bacteria,1VHP4@1239|Firmicutes,24S90@186801|Clostridia,3WH0V@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YYD3_k127_4929578_1	392499.Swit_3080	3.254e-55	210.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2K1GK@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_4929578_0	861299.J421_5906	1.892e-68	243.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4944286_4	1173264.KI913949_gene1080	8.95e-27	115.0	COG2764@1|root,COG2764@2|Bacteria,1G76J@1117|Cyanobacteria,1HBV7@1150|Oscillatoriales	1117|Cyanobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
YYD3_k127_4944286_5	268739.Nmlp_1153	1.596e-07	64.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,23SH5@183963|Halobacteria	183963|Halobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YYD3_k127_4944286_3	1283300.ATXB01000001_gene377	9.277e-29	122.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD3_k127_4944286_1	861299.J421_2845	3.745e-89	329.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSWP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD3_k127_4944286_0	251221.35211765	1.006e-154	519.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_4944286_6	215803.DB30_4238	0.0002263	53.0	COG4932@1|root,COG4932@2|Bacteria,1Q342@1224|Proteobacteria,433XR@68525|delta/epsilon subdivisions,2X40S@28221|Deltaproteobacteria,2YXUG@29|Myxococcales	28221|Deltaproteobacteria	M	Epidermal growth factor-like domain.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,EGF_3,LTD
YYD3_k127_4944286_2	1340493.JNIF01000003_gene4764	2.436e-32	128.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4952289_3	867903.ThesuDRAFT_01275	9.04e-130	426.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis	186801|Clostridia	C	acyl-CoA transferase carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
YYD3_k127_4952289_6	861299.J421_0149	2.09e-53	194.0	COG0122@1|root,COG0122@2|Bacteria,1ZTST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD3_k127_4952289_0	29581.BW37_00307	0.0	1026.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_4952289_10	1123248.KB893359_gene2175	0.0004983	49.0	2EH8M@1|root,33B0G@2|Bacteria,4NZHR@976|Bacteroidetes,1IZH9@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4952289_9	626418.bglu_2g12480	1.587e-31	143.0	COG4585@1|root,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1K250@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02486	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HATPase_c_2,HisKA_3,PAS,PAS_4,PAS_9
YYD3_k127_4952289_5	926566.Terro_3063	8.578e-68	236.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria,2JMQ5@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_4952289_8	797303.Natpe_1256	1.826e-33	140.0	COG1877@1|root,arCOG01216@2157|Archaea,2Y7FW@28890|Euryarchaeota,241GK@183963|Halobacteria	183963|Halobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
YYD3_k127_4952289_1	1210884.HG799462_gene8998	6.769e-175	569.0	COG0380@1|root,COG0380@2|Bacteria,2IYNH@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyltransferase family 20	-	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
YYD3_k127_4952289_4	1303518.CCALI_00534	1.922e-120	395.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_4952289_7	266117.Rxyl_0745	3.208e-38	148.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
YYD3_k127_4952289_2	926566.Terro_0874	1.764e-130	424.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
YYD3_k127_4958278_1	234267.Acid_6847	2.42e-161	530.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4958278_0	1150469.RSPPHO_02405	1.275e-202	638.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,2JPKH@204441|Rhodospirillales	204441|Rhodospirillales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
YYD3_k127_4958278_3	861299.J421_3911	4.651e-07	62.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
YYD3_k127_4958278_2	290397.Adeh_3668	8.033e-08	55.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions,2X5D2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
YYD3_k127_4959923_1	234267.Acid_3938	3.742e-170	563.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4959923_11	1123242.JH636434_gene5566	3.577e-08	62.0	COG3193@1|root,COG3193@2|Bacteria,2IZVP@203682|Planctomycetes	203682|Planctomycetes	O	Haem-degrading	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
YYD3_k127_4959923_5	864051.BurJ1DRAFT_2775	1.812e-80	280.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2WEME@28216|Betaproteobacteria,1KN2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_4959923_3	502025.Hoch_2041	1.177e-109	382.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_4959923_0	1082931.KKY_201	5.215e-179	578.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_4959923_9	234267.Acid_2558	5.109e-28	117.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_4959923_8	221288.JH992901_gene3196	3.369e-32	130.0	COG0797@1|root,COG0797@2|Bacteria	2|Bacteria	M	peptidoglycan binding	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
YYD3_k127_4959923_4	234267.Acid_7883	1.028e-85	302.0	COG1432@1|root,COG1432@2|Bacteria,3Y64C@57723|Acidobacteria	57723|Acidobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
YYD3_k127_4959923_10	311424.DhcVS_1093	4.053e-14	77.0	2A4E9@1|root,2ZJRI@2|Bacteria,2GAVU@200795|Chloroflexi,34DG2@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4959923_7	368407.Memar_2468	1.854e-46	183.0	COG2208@1|root,arCOG06893@2157|Archaea,2Y35A@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,SpoIIE
YYD3_k127_4959923_12	1370121.AUWS01000101_gene3577	0.0006732	51.0	COG5485@1|root,COG5485@2|Bacteria,2I0XQ@201174|Actinobacteria,235JN@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD3_k127_4959923_2	1379270.AUXF01000002_gene1601	3.002e-169	543.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsA	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
YYD3_k127_4959923_6	243090.RB3466	9.125e-74	251.0	COG0187@1|root,COG0187@2|Bacteria,2IWXP@203682|Planctomycetes	203682|Planctomycetes	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	-	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YYD3_k127_4960119_3	404589.Anae109_0232	1.896e-08	67.0	2DDTE@1|root,2ZJ6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4960119_0	671143.DAMO_1182	3.635e-95	317.0	COG0717@1|root,COG0717@2|Bacteria,2NQ5G@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
YYD3_k127_4960119_1	1121918.ARWE01000001_gene1208	9.349e-27	110.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,43SGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NDK	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YYD3_k127_4972869_0	1121920.AUAU01000017_gene1259	3.872e-243	757.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YYD3_k127_4980099_6	404589.Anae109_4096	0.0005459	48.0	COG1538@1|root,COG1538@2|Bacteria,1PKT6@1224|Proteobacteria,4354V@68525|delta/epsilon subdivisions,2X95H@28221|Deltaproteobacteria,2Z21V@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
YYD3_k127_4980099_0	1349767.GJA_4075	2.764e-197	642.0	COG4206@1|root,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,2VJZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YYD3_k127_4980099_3	243231.GSU3271	1.76e-32	145.0	COG3659@1|root,COG3659@2|Bacteria,1Q0I4@1224|Proteobacteria,42WBJ@68525|delta/epsilon subdivisions,2WS5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	-	-	-	-	-	-	-	-	-	OprB
YYD3_k127_4980099_4	1151119.KB895497_gene3332	9.853e-26	121.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,1WC24@1268|Micrococcaceae	201174|Actinobacteria	S	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
YYD3_k127_4980099_5	1057002.KB905370_gene649	2.011e-14	83.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2TTGG@28211|Alphaproteobacteria,4BCU6@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
YYD3_k127_4980099_1	1279017.AQYJ01000029_gene3976	3.513e-95	327.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,464J4@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YYD3_k127_49802_7	261292.Nit79A3_2861	1.811e-35	144.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,372CG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
YYD3_k127_49802_1	266117.Rxyl_1565	1.592e-199	630.0	COG0404@1|root,COG0404@2|Bacteria,2GPU4@201174|Actinobacteria,4CRTT@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM glycine cleavage T protein (aminomethyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
YYD3_k127_49802_0	1121904.ARBP01000003_gene6496	1.745e-255	816.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,47MWS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
YYD3_k127_49802_8	1396418.BATQ01000106_gene5355	3.297e-28	123.0	COG3794@1|root,COG3794@2|Bacteria,46SUG@74201|Verrucomicrobia,2IVQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_49802_6	401526.TcarDRAFT_1362	9.052e-47	188.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,4H6XD@909932|Negativicutes	909932|Negativicutes	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_49802_3	686340.Metal_0152	8.984e-81	281.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1XFND@135618|Methylococcales	135618|Methylococcales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
YYD3_k127_49802_4	479434.Sthe_3504	2.688e-72	262.0	COG3938@1|root,COG3938@2|Bacteria,2G5PY@200795|Chloroflexi,27YDV@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
YYD3_k127_49802_2	234267.Acid_5749	9.318e-191	631.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_49802_5	234267.Acid_7677	5.563e-60	213.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_4980992_3	292459.STH3190	2.379e-09	66.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
YYD3_k127_4980992_0	234267.Acid_2952	4.013e-36	149.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YYD3_k127_4980992_1	309803.CTN_0305	2.711e-14	78.0	COG0071@1|root,COG0071@2|Bacteria,2GDCG@200918|Thermotogae	200918|Thermotogae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD3_k127_4996275_18	1379270.AUXF01000003_gene3549	5.03e-11	70.0	COG2318@1|root,COG2318@2|Bacteria,1ZV6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_4996275_9	1116472.MGMO_59c00050	1.66e-43	165.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1XE83@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
YYD3_k127_4996275_8	1205680.CAKO01000029_gene5240	7.654e-45	165.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RNA signal recognition particle 4.5S RNA	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
YYD3_k127_4996275_13	497964.CfE428DRAFT_1821	3.712e-37	156.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_4996275_16	234267.Acid_4263	2.085e-18	97.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	2|Bacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
YYD3_k127_4996275_11	1267535.KB906767_gene3861	1.709e-37	151.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
YYD3_k127_4996275_12	926550.CLDAP_21910	3.711e-37	143.0	COG3631@1|root,COG3631@2|Bacteria,2G75M@200795|Chloroflexi	200795|Chloroflexi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
YYD3_k127_4996275_15	1118235.CAJH01000034_gene2170	3.807e-23	105.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,Response_reg
YYD3_k127_4996275_5	443143.GM18_1679	1.132e-102	346.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,43TZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
YYD3_k127_4996275_7	1500890.JQNL01000001_gene2993	1.545e-49	185.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1X7YN@135614|Xanthomonadales	135614|Xanthomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_4996275_2	1047013.AQSP01000079_gene2040	8.5e-221	723.0	COG0642@1|root,COG3290@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3	ko:K07315,ko:K12132,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	FeS,Fe_hyd_lg_C,Fer4,GGDEF,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Y_Y_Y
YYD3_k127_4996275_20	234267.Acid_3356	9.853e-07	51.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4996275_3	1265313.HRUBRA_01849	4.411e-189	621.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ_2
YYD3_k127_4996275_19	1121377.KB906400_gene1415	7.619e-09	67.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Fasciclin
YYD3_k127_4996275_1	234267.Acid_4582	6.113e-285	893.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
YYD3_k127_4996275_0	314230.DSM3645_17550	7.575e-294	928.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YYD3_k127_4996275_17	861299.J421_1108	2.433e-16	85.0	COG2318@1|root,COG2318@2|Bacteria,1ZV11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_4996275_6	1123073.KB899241_gene2228	3.15e-76	263.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,1X5VK@135614|Xanthomonadales	135614|Xanthomonadales	P	abc transporter atp-binding protein	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
YYD3_k127_4996275_4	1340493.JNIF01000003_gene4453	1.576e-156	508.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Methyltransf_25
YYD3_k127_4996275_10	1449976.KALB_3518	6.372e-40	158.0	COG0461@1|root,COG0461@2|Bacteria,2H5SI@201174|Actinobacteria,4EBR1@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YYD3_k127_4996275_14	234267.Acid_3837	1.218e-28	134.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_4996370_1	1123371.ATXH01000021_gene1117	8.082e-228	735.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YYD3_k127_4996370_4	234267.Acid_3785	1.377e-31	130.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_4996370_3	1123368.AUIS01000007_gene2721	1.56e-67	237.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
YYD3_k127_4996370_5	1267533.KB906733_gene3398	1.85e-27	126.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_4996370_6	204669.Acid345_3133	3.425e-26	122.0	COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
YYD3_k127_4996370_8	583345.Mmol_1817	0.0001184	53.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,2KME1@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YYD3_k127_4996370_2	880073.Calab_1177	6.766e-198	624.0	COG1260@1|root,COG1260@2|Bacteria,2NP2I@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
YYD3_k127_4996370_7	1047013.AQSP01000090_gene672	1.401e-17	89.0	2DF8J@1|root,2ZQXQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4996370_0	861299.J421_4196	0.0	1023.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD3_k127_5003127_1	935863.AWZR01000002_gene1024	4.026e-35	156.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
YYD3_k127_5003127_0	710696.Intca_1127	2.076e-91	335.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
YYD3_k127_5016640_0	1192034.CAP_8946	5.569e-30	121.0	COG0598@1|root,COG0598@2|Bacteria,1N04R@1224|Proteobacteria	1224|Proteobacteria	P	Magnesium transport protein CorA	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5016640_1	485913.Krac_9148	1.661e-19	100.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32,HTH_33
YYD3_k127_5016640_2	768710.DesyoDRAFT_1842	1.146e-15	85.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1V41H@1239|Firmicutes,24J23@186801|Clostridia	186801|Clostridia	L	Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32,HTH_33
YYD3_k127_5024391_4	234267.Acid_5283	3.267e-100	338.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YYD3_k127_5024391_1	404589.Anae109_0318	1.367e-155	507.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
YYD3_k127_5024391_8	1472418.BBJC01000004_gene1788	3.586e-10	66.0	2CBAE@1|root,31814@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5024391_7	555793.WSK_4047	3.113e-12	76.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5024391_0	1121438.JNJA01000001_gene2654	3.05e-253	792.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2M7XR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
YYD3_k127_5024391_5	1121472.AQWN01000004_gene660	3.921e-98	334.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
YYD3_k127_5024391_6	882.DVU_3395	2.124e-66	242.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD3_k127_5024391_3	945713.IALB_0156	1.676e-118	394.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
YYD3_k127_5024391_2	1191523.MROS_0721	6.879e-139	450.0	COG1932@1|root,COG1932@2|Bacteria	2|Bacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
YYD3_k127_5036683_1	903818.KI912268_gene1402	4.02e-150	485.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_5036683_2	765420.OSCT_2753	3.919e-125	407.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,3753Z@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD3_k127_5036683_0	204669.Acid345_2166	3.202e-207	657.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Dak2,DegV,Radical_SAM
YYD3_k127_5036683_3	1047013.AQSP01000090_gene667	4.184e-97	327.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_5036683_4	1267535.KB906767_gene328	1.185e-29	123.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_5047020_1	1382359.JIAL01000001_gene2863	3.175e-260	812.0	COG0466@1|root,COG0466@2|Bacteria,3Y3DI@57723|Acidobacteria,2JIB4@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_5047020_8	555088.DealDRAFT_1047	2.438e-35	141.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,42JZD@68298|Syntrophomonadaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
YYD3_k127_5047020_2	1267535.KB906767_gene3177	4.952e-222	696.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YYD3_k127_5047020_5	596152.DesU5LDRAFT_1163	5.782e-76	261.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2M9BR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
YYD3_k127_5047020_11	1283299.AUKG01000001_gene2241	0.0001679	55.0	2AX0P@1|root,31NYQ@2|Bacteria,2HPNT@201174|Actinobacteria,4CR19@84995|Rubrobacteria	84995|Rubrobacteria	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YYD3_k127_5047020_10	649764.HMPREF0762_01806	5.588e-28	116.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
YYD3_k127_5047020_6	292459.STH1622	4.244e-50	198.0	COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,1TQQU@1239|Firmicutes	1239|Firmicutes	L	Exonuclease	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
YYD3_k127_5047020_0	234267.Acid_0769	1.646e-290	912.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,3Y61D@57723|Acidobacteria	57723|Acidobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
YYD3_k127_5047020_9	1499967.BAYZ01000009_gene5328	1.738e-29	137.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
YYD3_k127_5047020_7	1297742.A176_03387	3.711e-44	170.0	COG0030@1|root,COG0030@2|Bacteria,1QXTN@1224|Proteobacteria	1224|Proteobacteria	J	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
YYD3_k127_5047020_4	204669.Acid345_2395	5.71e-105	371.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
YYD3_k127_5047020_3	861299.J421_4169	1.972e-140	464.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YYD3_k127_5048259_2	269799.Gmet_1651	3.198e-97	332.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD3_k127_5048259_0	63737.Npun_F1046	0.0	1180.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria,1HR8B@1161|Nostocales	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD3_k127_5048259_3	379066.GAU_2184	5.149e-39	151.0	COG1670@1|root,COG1670@2|Bacteria,1ZUYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YYD3_k127_5048259_1	1499967.BAYZ01000169_gene6694	8.001e-118	402.0	COG3437@1|root,COG4252@1|root,COG3437@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	-	-	4.6.1.1	ko:K01768,ko:K07814	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	CHASE2,HD,HD_5,Pkinase,Response_reg
YYD3_k127_5057898_3	1116472.MGMO_112c00020	4.096e-67	247.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5057898_14	1419583.V466_30385	9.684e-07	56.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5057898_1	452637.Oter_1869	3.891e-104	370.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_5057898_7	1267534.KB906756_gene50	2.163e-35	141.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_5057898_10	555793.WSK_4047	2.989e-19	100.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5057898_8	658086.HMPREF0994_04008	4.588e-26	117.0	COG1011@1|root,COG1011@2|Bacteria,1VB3V@1239|Firmicutes,24FSK@186801|Clostridia,27N8P@186928|unclassified Lachnospiraceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YYD3_k127_5057898_5	1340493.JNIF01000003_gene4709	6.297e-50	194.0	2EQTB@1|root,33ID2@2|Bacteria	2|Bacteria	S	Lytic polysaccharide mono-oxygenase, cellulose-degrading	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10
YYD3_k127_5057898_6	595460.RRSWK_07231	1.203e-43	163.0	COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5057898_2	97096.XP_007790920.1	1.545e-100	349.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_5057898_0	1267533.KB906735_gene4931	1.337e-228	720.0	COG1032@1|root,COG1032@2|Bacteria,3Y7D8@57723|Acidobacteria,2JMKA@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_5057898_11	1123269.NX02_25980	5.735e-18	94.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U8U8@28211|Alphaproteobacteria,2KCU8@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
YYD3_k127_5057898_12	161528.ED21_17847	2.973e-16	93.0	COG3710@1|root,COG3710@2|Bacteria,1PE98@1224|Proteobacteria,2VD0F@28211|Alphaproteobacteria,2K3KN@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
YYD3_k127_5057898_4	234267.Acid_7679	1.217e-66	253.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5057898_9	1267534.KB906754_gene3169	4.666e-24	113.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	aglU	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Trans_reg_C,WD40
YYD3_k127_5129529_5	401053.AciPR4_3363	1.685e-56	226.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5129529_6	1144325.PMI22_02237	1.482e-05	56.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3,SnoaL_4
YYD3_k127_5129529_7	1131814.JAFO01000001_gene3728	2.341e-05	55.0	COG4319@1|root,COG4319@2|Bacteria,1R2QC@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_5129529_3	272123.Anacy_1153	1.287e-61	220.0	COG2197@1|root,COG2197@2|Bacteria,1G5A4@1117|Cyanobacteria,1HMEN@1161|Nostocales	1117|Cyanobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
YYD3_k127_5129529_1	1242864.D187_002995	3.783e-115	407.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
YYD3_k127_5129529_0	1144275.COCOR_06233	1.818e-197	627.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
YYD3_k127_5129529_2	635013.TherJR_3000	6.66e-85	288.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
YYD3_k127_5129529_4	1121468.AUBR01000015_gene2244	2.702e-61	226.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,42FH2@68295|Thermoanaerobacterales	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YYD3_k127_5133305_0	448385.sce5149	2.215e-167	535.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437UC@68525|delta/epsilon subdivisions,2X33Z@28221|Deltaproteobacteria,2YU4A@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_5133305_2	204669.Acid345_0784	8.952e-77	289.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria,2JK9M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_5133305_1	234267.Acid_1599	5.737e-101	336.0	COG0793@1|root,COG0793@2|Bacteria,3Y6R0@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
YYD3_k127_5171149_1	1288494.EBAPG3_5720	1.24e-111	370.0	COG0457@1|root,COG4976@1|root,COG0457@2|Bacteria,COG4976@2|Bacteria,1MVMG@1224|Proteobacteria,2WH7Y@28216|Betaproteobacteria,372FY@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
YYD3_k127_5171149_0	1288494.EBAPG3_5740	6.139e-202	651.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	rhs element vgr protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
YYD3_k127_5171149_2	1278073.MYSTI_04904	2.43e-84	297.0	2CACF@1|root,340J2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5178531_10	1047013.AQSP01000036_gene1385	2.398e-93	327.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
YYD3_k127_5178531_23	1242864.D187_010209	3.369e-25	118.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
YYD3_k127_5178531_29	926550.CLDAP_22710	5.749e-13	82.0	COG0457@1|root,COG0457@2|Bacteria	926550.CLDAP_22710|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5178531_13	525904.Tter_1075	6.41e-79	280.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YYD3_k127_5178531_3	1095769.CAHF01000023_gene486	5.768e-121	403.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,474BV@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YYD3_k127_5178531_16	204669.Acid345_0261	3.889e-59	210.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria,2JJ0X@204432|Acidobacteriia	204432|Acidobacteriia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YYD3_k127_5178531_6	338963.Pcar_1919	2.605e-101	336.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YYD3_k127_5178531_15	771875.Ferpe_0617	1.84e-72	250.0	COG0264@1|root,COG0264@2|Bacteria,2GCGY@200918|Thermotogae	200918|Thermotogae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YYD3_k127_5178531_7	204669.Acid345_0563	4.238e-101	337.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YYD3_k127_5178531_19	234267.Acid_0907	5.61e-44	164.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YYD3_k127_5178531_17	443254.Marpi_1669	6.277e-47	177.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YYD3_k127_5178531_9	404589.Anae109_0686	6.882e-96	325.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YYD3_k127_5178531_28	330214.NIDE1349	1.658e-13	79.0	COG3166@1|root,COG3166@2|Bacteria,3J1EX@40117|Nitrospirae	40117|Nitrospirae	NU	Fimbrial assembly protein (PilN)	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
YYD3_k127_5178531_25	589865.DaAHT2_2311	4.221e-19	94.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
YYD3_k127_5178531_4	1047013.AQSP01000124_gene2676	4.314e-106	373.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
YYD3_k127_5178531_24	1333523.L593_04100	1.503e-20	103.0	COG3291@1|root,arCOG02546@2157|Archaea	2157|Archaea	M	protein contain chitin-binding domain type 3	-	-	3.2.1.14,3.2.1.202	ko:K01183,ko:K21606	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	CBM5,GH18	-	CARDB,Glyco_hydro_18,Malectin,PKD
YYD3_k127_5178531_30	379066.GAU_1928	1.296e-12	74.0	COG0457@1|root,COG0457@2|Bacteria,1ZTTU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_5178531_12	1120972.AUMH01000003_gene2874	2.538e-81	286.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,27894@186823|Alicyclobacillaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YYD3_k127_5178531_21	204669.Acid345_3288	7.276e-38	147.0	COG0511@1|root,COG0511@2|Bacteria,3Y4W8@57723|Acidobacteria,2JJHQ@204432|Acidobacteriia	204432|Acidobacteriia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
YYD3_k127_5178531_2	1382359.JIAL01000001_gene1629	6.479e-192	610.0	COG0439@1|root,COG0439@2|Bacteria,3Y2QZ@57723|Acidobacteria,2JIFS@204432|Acidobacteriia	204432|Acidobacteriia	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD3_k127_5178531_22	234267.Acid_4942	1.289e-29	126.0	COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria	57723|Acidobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YYD3_k127_5178531_1	391596.PBAL39_06481	1.681e-211	666.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
YYD3_k127_5178531_8	204669.Acid345_4424	1.443e-96	329.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JIT2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
YYD3_k127_5178531_20	767029.HMPREF9154_1897	4.619e-43	164.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4DQNK@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
YYD3_k127_5178531_18	644282.Deba_1300	3.159e-46	184.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
YYD3_k127_5178531_5	240015.ACP_1676	1.014e-102	349.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,3Y4I2@57723|Acidobacteria,2JIKP@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
YYD3_k127_5178531_11	443144.GM21_2612	4.589e-93	313.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,43TJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM DAHP synthetase I KDSA	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
YYD3_k127_5178531_0	204669.Acid345_3670	3.132e-233	733.0	COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
YYD3_k127_5178531_14	269799.Gmet_1275	6.008e-78	268.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YYD3_k127_5181279_8	234267.Acid_3223	2.955e-11	70.0	28ZVZ@1|root,2ZMKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5181279_1	204669.Acid345_1052	1.92e-116	404.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YYD3_k127_5181279_3	1379270.AUXF01000007_gene993	8.692e-97	329.0	COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,FlgD_ig,NHL
YYD3_k127_5181279_7	1267533.KB906734_gene4302	2.335e-32	134.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria	57723|Acidobacteria	KU	WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
YYD3_k127_5181279_5	234267.Acid_1440	8.126e-53	201.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
YYD3_k127_5181279_0	234267.Acid_0873	5.71e-189	613.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_5181279_6	595460.RRSWK_01547	1.311e-46	180.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563,ko:K10947	-	-	R07233	RC00003	ko00000,ko01000,ko03000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
YYD3_k127_5181279_2	234267.Acid_5749	8.385e-106	375.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5181279_4	627192.SLG_25160	2.576e-59	218.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5184843_4	886293.Sinac_1155	5.451e-64	236.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
YYD3_k127_5184843_2	886293.Sinac_1154	5.676e-120	402.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_5184843_0	886293.Sinac_1153	8.295e-228	734.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_5184843_6	562970.Btus_2709	9.662e-44	173.0	COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,27AH9@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
YYD3_k127_5184843_5	1415166.NONO_c27280	5.514e-63	230.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4FZWH@85025|Nocardiaceae	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
YYD3_k127_5184843_3	1082931.KKY_114	3.26e-96	326.0	COG0346@1|root,COG0346@2|Bacteria,1P6TT@1224|Proteobacteria,2TQXR@28211|Alphaproteobacteria,3N6NT@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15242,ko:K15975	ko00361,ko01100,ko01120,ko01220,map00361,map01100,map01120,map01220	-	R05408	RC02673	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
YYD3_k127_5184843_7	1047013.AQSP01000100_gene599	5.552e-25	123.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_5184843_1	1123023.JIAI01000013_gene4029	1.521e-142	461.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
YYD3_k127_5184843_8	204669.Acid345_3841	2.525e-07	63.0	COG1629@1|root,COG4771@2|Bacteria	204669.Acid345_3841|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5187158_4	1340493.JNIF01000003_gene2123	2.414e-17	93.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5187158_1	335543.Sfum_1617	4.959e-163	530.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_5187158_0	1442599.JAAN01000005_gene979	3.209e-163	518.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1X45W@135614|Xanthomonadales	135614|Xanthomonadales	S	4-oxalomesaconate hydratase	fldW	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
YYD3_k127_5187158_2	234267.Acid_6636	3.54e-98	329.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	ligK	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
YYD3_k127_5187158_3	204669.Acid345_2675	8.281e-30	138.0	COG1629@1|root,COG1629@2|Bacteria,3Y98Z@57723|Acidobacteria,2JI5U@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5195917_1	1366050.N234_28175	3.341e-153	490.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VHCF@28216|Betaproteobacteria,1K6E3@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Amidase	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
YYD3_k127_5195917_4	1366050.N234_28175	8.324e-31	126.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VHCF@28216|Betaproteobacteria,1K6E3@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Amidase	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
YYD3_k127_5195917_3	1037409.BJ6T_58330	6.165e-47	174.0	COG3439@1|root,COG3439@2|Bacteria,1RBY0@1224|Proteobacteria,2U5Y0@28211|Alphaproteobacteria,3JYKW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YYD3_k127_5195917_0	1366050.N234_30720	1.026e-183	578.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2W1R8@28216|Betaproteobacteria,1KGRA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
YYD3_k127_5195917_2	935557.ATYB01000008_gene5508	1.136e-102	336.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2TSCE@28211|Alphaproteobacteria,4B88J@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_5206371_4	1340493.JNIF01000003_gene1440	1.494e-46	175.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
YYD3_k127_5206371_0	1379270.AUXF01000002_gene1510	4.473e-130	430.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
YYD3_k127_5206371_5	1267534.KB906755_gene4131	1.391e-40	156.0	COG3801@1|root,COG3801@2|Bacteria	2|Bacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
YYD3_k127_5206371_6	1300345.LF41_1708	2.761e-24	113.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,1T055@1236|Gammaproteobacteria,1X6SQ@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5206371_7	987059.RBXJA2T_19014	9.604e-13	77.0	COG0500@1|root,COG0500@2|Bacteria,1R1VS@1224|Proteobacteria,2WI6B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_5206371_1	314230.DSM3645_20627	1.649e-127	422.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_5206371_3	344747.PM8797T_05400	1.621e-73	264.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_5206371_2	97096.XP_007790920.1	5.94e-116	393.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_520962_4	404589.Anae109_3198	2.127e-20	100.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
YYD3_k127_520962_2	215803.DB30_6887	1.846e-66	235.0	COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,4347C@68525|delta/epsilon subdivisions,2X9UQ@28221|Deltaproteobacteria,2YWCK@29|Myxococcales	28221|Deltaproteobacteria	K	TipAS antibiotic-recognition domain	-	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
YYD3_k127_520962_7	67352.JODS01000058_gene6854	2.764e-07	62.0	COG3631@1|root,COG3631@2|Bacteria,2INUG@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_520962_6	298655.KI912267_gene7225	2.64e-08	63.0	COG5517@1|root,COG5517@2|Bacteria,2IHV4@201174|Actinobacteria	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_520962_1	383372.Rcas_2848	1.709e-73	259.0	COG3386@1|root,COG3386@2|Bacteria,2G76H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
YYD3_k127_520962_3	401053.AciPR4_3363	9.65e-60	236.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_520962_5	1096546.WYO_0581	1.991e-18	93.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,1JQQ4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb,TAT_signal
YYD3_k127_520962_0	1123228.AUIH01000056_gene3750	3.947e-201	639.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RQK3@1236|Gammaproteobacteria,1XNN3@135619|Oceanospirillales	135619|Oceanospirillales	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5216316_12	1267535.KB906767_gene4945	8.814e-38	149.0	COG0251@1|root,COG0251@2|Bacteria,3Y5DN@57723|Acidobacteria,2JN2R@204432|Acidobacteriia	204432|Acidobacteriia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YYD3_k127_5216316_18	1304885.AUEY01000050_gene1196	1.768e-20	93.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MKZY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YYD3_k127_5216316_22	515635.Dtur_0904	1.023e-09	67.0	2EGFY@1|root,33A7X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5216316_20	289376.THEYE_A1545	4.251e-16	85.0	COG1734@1|root,COG1734@2|Bacteria,3J0R1@40117|Nitrospirae	40117|Nitrospirae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YYD3_k127_5216316_1	240015.ACP_0609	2.89e-279	882.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria,2JHMJ@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_5216316_15	1121405.dsmv_2237	1.396e-32	142.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42W8P@68525|delta/epsilon subdivisions,2WRV4@28221|Deltaproteobacteria,2MKN4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YYD3_k127_5216316_6	243231.GSU0082	2.578e-77	270.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,43T73@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD3_k127_5216316_8	204669.Acid345_2869	4.163e-60	217.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria,2JJTI@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YYD3_k127_5216316_16	1116472.MGMO_77c00020	6.676e-32	132.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XF1R@135618|Methylococcales	135618|Methylococcales	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YYD3_k127_5216316_0	316067.Geob_0392	1.18e-321	1009.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YYD3_k127_5216316_4	316274.Haur_2806	5.66e-100	342.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,37674@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_5216316_7	383372.Rcas_3546	7.449e-67	246.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_5216316_19	552811.Dehly_0588	2.229e-20	100.0	COG1011@1|root,COG1011@2|Bacteria,2G78N@200795|Chloroflexi,34D8N@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YYD3_k127_5216316_10	1158146.KB907131_gene1308	1.3e-47	179.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
YYD3_k127_5216316_9	56780.SYN_01794	3.715e-53	198.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MQKB@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
YYD3_k127_5216316_3	1382359.JIAL01000001_gene1363	8.8e-141	456.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria,2JHYH@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YYD3_k127_5216316_21	309801.trd_1708	7.236e-12	75.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
YYD3_k127_5216316_14	1382306.JNIM01000001_gene1158	1.464e-36	143.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
YYD3_k127_5216316_11	204669.Acid345_4082	9.014e-40	157.0	28QZS@1|root,2ZDEJ@2|Bacteria,3Y4BV@57723|Acidobacteria,2JKG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5216316_5	525904.Tter_0647	1.006e-78	274.0	COG0351@1|root,COG0351@2|Bacteria,2NP3M@2323|unclassified Bacteria	2|Bacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00868,ko:K00941,ko:K03147,ko:K21219	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS03115	Phos_pyr_kin
YYD3_k127_5216316_13	1382356.JQMP01000001_gene1206	2.973e-37	148.0	COG1268@1|root,COG1268@2|Bacteria,2GBUZ@200795|Chloroflexi,27YWE@189775|Thermomicrobia	189775|Thermomicrobia	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
YYD3_k127_5216316_17	247490.KSU1_B0196	5.082e-31	133.0	COG4798@1|root,COG4798@2|Bacteria,2J4ZF@203682|Planctomycetes	203682|Planctomycetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_5216316_2	696369.KI912183_gene2634	7.786e-150	487.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,260SP@186807|Peptococcaceae	186801|Clostridia	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
YYD3_k127_5217012_9	204669.Acid345_1255	1.66e-51	187.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YYD3_k127_5217012_2	443144.GM21_3302	4.162e-87	293.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YYD3_k127_5217012_10	1267533.KB906735_gene5105	7.862e-50	181.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YYD3_k127_5217012_11	697303.Thewi_2230	2.417e-49	179.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
YYD3_k127_5217012_20	1267534.KB906757_gene797	8.88e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,3Y5X6@57723|Acidobacteria,2JK4W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
YYD3_k127_5217012_19	765910.MARPU_11590	4.556e-13	71.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1WZ35@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
YYD3_k127_5217012_1	1120973.AQXL01000112_gene1094	1.979e-93	314.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD3_k127_5217012_8	589924.Ferp_1104	4.089e-52	197.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
YYD3_k127_5217012_0	1047013.AQSP01000074_gene1894	9.28e-189	599.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
YYD3_k127_5217012_13	858215.Thexy_0353	3.744e-45	168.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
YYD3_k127_5217012_21	309801.trd_0967	6.454e-12	74.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,27YRK@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
YYD3_k127_5217012_5	429009.Adeg_1507	1.233e-61	216.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,42IHF@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
YYD3_k127_5217012_14	682795.AciX8_0589	1.051e-38	147.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria,2JJPM@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
YYD3_k127_5217012_6	1451189.CFAL_10005	2.576e-56	201.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,22KFS@1653|Corynebacteriaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
YYD3_k127_5217012_12	1267534.KB906757_gene807	4.115e-46	170.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria,2JJ74@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
YYD3_k127_5217012_17	1340493.JNIF01000003_gene3220	2.53e-20	93.0	COG0199@1|root,COG0199@2|Bacteria,3Y5HM@57723|Acidobacteria	57723|Acidobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
YYD3_k127_5217012_3	204669.Acid345_1238	2.647e-78	270.0	COG0094@1|root,COG0094@2|Bacteria,3Y3PS@57723|Acidobacteria,2JHV4@204432|Acidobacteriia	204432|Acidobacteriia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
YYD3_k127_5217012_18	1260251.SPISAL_07420	9.109e-20	93.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales	135613|Chromatiales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
YYD3_k127_5217012_7	401053.AciPR4_3226	2.184e-54	192.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
YYD3_k127_5217012_15	1382304.JNIL01000001_gene1956	7.303e-24	105.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
YYD3_k127_5217012_22	1380394.JADL01000007_gene4711	8.6e-09	61.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,2JUAU@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
YYD3_k127_5217012_4	204669.Acid345_1233	3.81e-66	228.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria,2JJ2G@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YYD3_k127_5217012_16	1286631.X805_18100	1.656e-22	98.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,1KIUV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YYD3_k127_5241070_1	234267.Acid_5749	4.061e-104	352.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5241070_3	1336233.JAEH01000055_gene4125	8.304e-33	141.0	COG0491@1|root,COG0491@2|Bacteria,1PBSA@1224|Proteobacteria,1SWGM@1236|Gammaproteobacteria,2QE2R@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5241070_0	313603.FB2170_01896	4.645e-109	371.0	COG2333@1|root,COG2333@2|Bacteria,4NMP4@976|Bacteroidetes,1I17N@117743|Flavobacteriia	976|Bacteroidetes	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5241070_7	153496.JNAB01000013_gene1169	4.881e-05	53.0	2ESJ3@1|root,33K3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YYD3_k127_5241070_5	1267534.KB906755_gene4131	7.513e-21	96.0	COG3801@1|root,COG3801@2|Bacteria	2|Bacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
YYD3_k127_5241070_2	1121875.KB907549_gene1896	4.332e-99	333.0	COG0604@1|root,COG0604@2|Bacteria,4NJ5X@976|Bacteroidetes,1IIKA@117743|Flavobacteriia	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
YYD3_k127_5241070_4	266117.Rxyl_0148	1.07e-22	104.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4CQ50@84995|Rubrobacteria	84995|Rubrobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_5241070_6	1449346.JQMO01000002_gene388	1.762e-12	73.0	COG1878@1|root,COG1878@2|Bacteria,2GK9Y@201174|Actinobacteria,2M668@2063|Kitasatospora	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_5247280_1	1396141.BATP01000025_gene931	3.313e-65	235.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YYD3_k127_5247280_0	278963.ATWD01000001_gene3362	1.359e-120	396.0	COG0667@1|root,COG0667@2|Bacteria,3Y61M@57723|Acidobacteria	57723|Acidobacteria	C	TAT (twin-arginine translocation) pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,TAT_signal
YYD3_k127_5247280_2	339670.Bamb_1810	6.732e-55	193.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria,1K8MD@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
YYD3_k127_5250081_1	379066.GAU_3151	9.396e-46	173.0	2E0TE@1|root,32WB2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5250081_0	1211777.BN77_p11114	2.659e-105	369.0	COG2202@1|root,COG2984@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
YYD3_k127_5266439_2	234267.Acid_7680	1.099e-28	118.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5266439_1	247633.GP2143_18121	1.082e-30	132.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5266439_0	234267.Acid_3938	1.715e-86	309.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5282891_4	426117.M446_6554	6.8e-79	274.0	COG0373@1|root,COG0373@2|Bacteria,1R5VH@1224|Proteobacteria,2TQT9@28211|Alphaproteobacteria,1JT9R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	PFAM Methylene-tetrahydromethanopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Mpt_N,THF_DHG_CYH_C
YYD3_k127_5282891_5	667632.KB890164_gene1986	2.648e-70	241.0	COG1795@1|root,COG1795@2|Bacteria,1NDRY@1224|Proteobacteria,2VJ22@28216|Betaproteobacteria,1K2EY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	formaldehyde-activating enzyme	fae	-	4.2.1.147	ko:K10713	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R08058	RC01583,RC01795	ko00000,ko00001,ko01000	-	-	-	Fae
YYD3_k127_5282891_10	639030.JHVA01000001_gene1885	2.57e-11	69.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5282891_7	1279017.AQYJ01000028_gene2525	2.156e-34	152.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5282891_11	715451.ambt_12010	8.313e-07	62.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5282891_6	1122138.AQUZ01000004_gene891	3.228e-38	145.0	COG3080@1|root,COG3080@2|Bacteria,2IMEN@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1555	Fumarate_red_D
YYD3_k127_5282891_8	419947.MRA_1566	6.239e-30	130.0	COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria,23A9K@1762|Mycobacteriaceae	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
YYD3_k127_5282891_3	1122138.AQUZ01000004_gene889	2.387e-120	397.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YYD3_k127_5282891_0	1122138.AQUZ01000004_gene888	3.471e-293	908.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DPTE@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	frdA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1552	FAD_binding_2,Succ_DH_flav_C
YYD3_k127_5282891_9	1123024.AUII01000011_gene4423	1.808e-15	78.0	2BJGQ@1|root,32DTH@2|Bacteria,2GUXX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5282891_1	1379270.AUXF01000001_gene2134	2.944e-169	544.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	oxlT	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
YYD3_k127_5282891_2	1254432.SCE1572_47425	5.616e-125	411.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD3_k127_5288037_1	1267535.KB906767_gene5003	1.631e-18	87.0	COG1574@1|root,COG1574@2|Bacteria,3Y7EK@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_5288037_0	1279017.AQYJ01000028_gene2525	7.457e-31	129.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5300137_2	1089547.KB913013_gene3021	1.224e-21	104.0	COG1082@1|root,COG1082@2|Bacteria,4NEUS@976|Bacteroidetes,47NHQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_5300137_3	471853.Bcav_4110	1.519e-06	59.0	COG4932@1|root,COG4932@2|Bacteria,2IAMD@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SdrD_B
YYD3_k127_5300137_0	1267535.KB906767_gene1178	7.264e-202	654.0	28JZZ@1|root,2Z9PZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5300137_1	335543.Sfum_3557	1.327e-67	238.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2WK1W@28221|Deltaproteobacteria,2MQCQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
YYD3_k127_5314682_0	247634.GPB2148_3282	5.105e-146	485.0	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,1J8Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
YYD3_k127_5314682_1	448385.sce6263	6.959e-48	179.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
YYD3_k127_5331332_0	935840.JAEQ01000003_gene279	5.831e-190	599.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	2.1.1.341	ko:K15066	ko00627,ko01120,map00627,map01120	-	R09271,R10136	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_5331332_2	269797.Mbar_A1437	3.799e-65	233.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2N9HJ@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
YYD3_k127_5331332_3	234267.Acid_0799	3.625e-36	148.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YYD3_k127_5331332_1	401053.AciPR4_3549	7.731e-78	268.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
YYD3_k127_5331332_4	234267.Acid_2181	3.144e-23	102.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase internal region	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
YYD3_k127_5336405_0	1121920.AUAU01000026_gene1453	1.417e-233	736.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD3_k127_5336405_3	1121920.AUAU01000026_gene1452	6.1e-30	121.0	COG2127@1|root,COG2127@2|Bacteria	2|Bacteria	T	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
YYD3_k127_5336405_1	1163617.SCD_n01859	3.383e-84	285.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
YYD3_k127_5336405_2	379066.GAU_2073	5.081e-80	276.0	COG0008@1|root,COG0008@2|Bacteria,1ZURR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
YYD3_k127_5336405_5	1396141.BATP01000034_gene4171	1.566e-16	88.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	74201|Verrucomicrobia	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_5336405_6	1292034.OR37_02289	7.179e-08	64.0	COG0392@1|root,COG0392@2|Bacteria,1RF8R@1224|Proteobacteria,2U7DD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
YYD3_k127_5336405_7	1123234.AUKI01000016_gene2974	5.12e-07	58.0	2A8XB@1|root,30Y0U@2|Bacteria,4NSDA@976|Bacteroidetes,1I4EZ@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YYD3_k127_5336405_4	204669.Acid345_1842	4.304e-17	88.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5343186_0	1232410.KI421414_gene2855	2.237e-83	282.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,43T7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD3_k127_5343186_1	1095769.CAHF01000005_gene1636	7.295e-14	79.0	2DKFZ@1|root,309D6@2|Bacteria,1QZK6@1224|Proteobacteria,2WHMG@28216|Betaproteobacteria,476NY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
YYD3_k127_5363370_1	1267535.KB906767_gene4740	1.167e-19	97.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_5363370_0	472759.Nhal_1864	4.013e-33	135.0	COG5573@1|root,COG5573@2|Bacteria,1N9U9@1224|Proteobacteria,1SY93@1236|Gammaproteobacteria,1X2IB@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_5363370_2	1121377.KB906412_gene740	2.744e-14	82.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hen1_L,Methyltransf_12,Methyltransf_23,Methyltransf_25
YYD3_k127_5396472_0	316067.Geob_3570	6.665e-191	609.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42P4F@68525|delta/epsilon subdivisions,2WJVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
YYD3_k127_5396472_2	765911.Thivi_0287	5.112e-40	152.0	COG4251@1|root,COG4251@2|Bacteria,1N1KJ@1224|Proteobacteria,1SD1J@1236|Gammaproteobacteria,1WZD7@135613|Chromatiales	135613|Chromatiales	T	PFAM KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
YYD3_k127_5396472_3	497964.CfE428DRAFT_5867	3.343e-32	132.0	COG4251@1|root,COG4251@2|Bacteria,46WB9@74201|Verrucomicrobia	74201|Verrucomicrobia	T	KaiB	-	-	-	-	-	-	-	-	-	-	-	-	KaiB
YYD3_k127_5396472_1	1123242.JH636434_gene4662	7.243e-48	182.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_5411068_2	1267535.KB906767_gene3864	3.121e-43	162.0	COG2807@1|root,COG2807@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_5411068_8	1047013.AQSP01000110_gene82	1.496e-05	57.0	2CI8B@1|root,334QN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5411068_5	1125863.JAFN01000001_gene1217	3.387e-23	106.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,42SCH@68525|delta/epsilon subdivisions,2WPMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
YYD3_k127_5411068_7	1334046.AYTB01000002_gene1818	1.906e-10	64.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli	91061|Bacilli	K	Cold-Shock Protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YYD3_k127_5411068_6	644076.SCH4B_1992	2.191e-11	74.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,4NAVV@97050|Ruegeria	28211|Alphaproteobacteria	Q	ABC transporter, ATP-binding protein	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD3_k127_5411068_1	246197.MXAN_2739	7.835e-57	209.0	COG0613@1|root,COG0613@2|Bacteria,1QV9S@1224|Proteobacteria,43BP1@68525|delta/epsilon subdivisions,2X70C@28221|Deltaproteobacteria,2YWF9@29|Myxococcales	28221|Deltaproteobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
YYD3_k127_5411068_4	1121441.AUCX01000009_gene2470	4.109e-26	121.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2X5PR@28221|Deltaproteobacteria,2MBC8@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YYD3_k127_5411068_3	1162668.LFE_0723	2.787e-32	130.0	COG0316@1|root,COG0316@2|Bacteria,3J0TZ@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the HesB IscA family	-	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
YYD3_k127_5411068_0	1340493.JNIF01000003_gene4371	1.627e-230	722.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,3Y2FA@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YYD3_k127_5412025_5	234267.Acid_5846	1.722e-31	126.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_5412025_7	1453503.AU05_22815	0.0005151	52.0	2B4C3@1|root,31X3M@2|Bacteria,1RINY@1224|Proteobacteria	1224|Proteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
YYD3_k127_5412025_6	1123508.JH636440_gene2608	1.944e-28	122.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
YYD3_k127_5412025_3	935837.JAEK01000034_gene3041	3.987e-42	159.0	COG0346@1|root,COG0346@2|Bacteria,1VH3Z@1239|Firmicutes,4HNY3@91061|Bacilli,1ZGZ5@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_5412025_0	1340493.JNIF01000003_gene3965	1.258e-127	428.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_5412025_2	450851.PHZ_c3077	4.407e-49	189.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5412025_4	247633.GP2143_17801	6.369e-42	158.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5412025_1	1379270.AUXF01000001_gene2129	3.073e-98	332.0	COG1304@1|root,COG1304@2|Bacteria,1ZUNQ@142182|Gemmatimonadetes	2|Bacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.15,1.1.3.46	ko:K00104,ko:K16422	ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130	-	R00475,R06633	RC00042,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
YYD3_k127_5493818_0	234267.Acid_3938	3.459e-176	586.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5493818_1	204669.Acid345_3552	4.843e-87	304.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K03408,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,CheW,HATPase_c,HisKA,Methyltransf_11,Methyltransf_25,PAS_10,Response_reg
YYD3_k127_5493818_3	247633.GP2143_18131	8.761e-43	171.0	2C42J@1|root,3359Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5493818_2	247633.GP2143_17796	4.298e-51	194.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5493818_5	1047013.AQSP01000106_gene1763	1.885e-33	151.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_5493818_6	234267.Acid_5940	2.072e-31	136.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_5493818_4	706587.Desti_3024	4.148e-35	136.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,43DPM@68525|delta/epsilon subdivisions,2X9UC@28221|Deltaproteobacteria,2MS8D@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_5509162_15	1123377.AUIV01000011_gene2106	4.708e-05	49.0	2BQK0@1|root,32JG2@2|Bacteria,1MYHR@1224|Proteobacteria,1TD82@1236|Gammaproteobacteria,1XAAT@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5509162_4	903818.KI912268_gene1318	7.649e-149	493.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
YYD3_k127_5509162_9	757424.Hsero_4788	8.313e-46	174.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2VRSU@28216|Betaproteobacteria,474F4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Lipocalin-like domain	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
YYD3_k127_5509162_5	1232410.KI421413_gene633	5.356e-84	281.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,42QWQ@68525|delta/epsilon subdivisions,2WMRI@28221|Deltaproteobacteria,43T93@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5509162_8	671143.DAMO_1446	3.776e-54	198.0	COG0500@1|root,COG2226@2|Bacteria,2NPUA@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
YYD3_k127_5509162_2	1123504.JQKD01000015_gene955	2.46e-179	593.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,2VIQ0@28216|Betaproteobacteria	28216|Betaproteobacteria	G	synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
YYD3_k127_5509162_1	644968.DFW101_2127	5.032e-231	734.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2M9SK@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
YYD3_k127_5509162_3	861299.J421_3806	1.844e-172	561.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
YYD3_k127_5509162_0	713587.THITH_11260	4.309e-299	933.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
YYD3_k127_5509162_13	351160.RCIX2272	7.162e-16	88.0	COG1413@1|root,arCOG02970@2157|Archaea	2157|Archaea	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YYD3_k127_5509162_6	861299.J421_1461	1.963e-70	261.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
YYD3_k127_5509162_10	886293.Sinac_6279	7.397e-45	166.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_5509162_11	1174528.JH992893_gene5895	3.192e-43	166.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1JH83@1189|Stigonemataceae	1117|Cyanobacteria	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YYD3_k127_5509162_12	1279017.AQYJ01000028_gene2525	1.87e-42	176.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5509162_16	218284.CCDN010000001_gene445	0.0009127	49.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
YYD3_k127_5509162_7	1246995.AFR_14235	1.832e-65	235.0	COG2207@1|root,COG4978@1|root,COG2207@2|Bacteria,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria,4DGGS@85008|Micromonosporales	201174|Actinobacteria	KT	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
YYD3_k127_551635_0	1267535.KB906767_gene5132	1.336e-93	315.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_551635_1	247633.GP2143_17796	4.562e-40	161.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5516736_0	266265.Bxe_B1521	1.553e-96	332.0	COG0642@1|root,COG2205@2|Bacteria,1R8JB@1224|Proteobacteria,2WAVF@28216|Betaproteobacteria,1K493@119060|Burkholderiaceae	28216|Betaproteobacteria	F	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YYD3_k127_5528463_3	234267.Acid_1440	3.301e-14	81.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
YYD3_k127_5528463_2	1123276.KB893301_gene4293	5.66e-22	104.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,47V7E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5528463_0	234267.Acid_6847	1.424e-173	576.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5528463_4	555793.WSK_0157	3.198e-07	59.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,2U7U4@28211|Alphaproteobacteria,2K7J3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5528463_1	443143.GM18_0358	6.625e-64	223.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
YYD3_k127_5531477_14	401053.AciPR4_0638	6.938e-10	72.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Y0@57723|Acidobacteria,2JIYU@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5531477_13	626418.bglu_1g26950	6.14e-20	96.0	COG3794@1|root,COG3794@2|Bacteria,1RH5A@1224|Proteobacteria,2VSEN@28216|Betaproteobacteria,1K851@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
YYD3_k127_5531477_11	1175306.GWL_07060	2.101e-66	238.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2VNTG@28216|Betaproteobacteria,478MY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Ndr family	catD2	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
YYD3_k127_5531477_8	1123023.JIAI01000013_gene4027	1.076e-92	317.0	COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively	ligB	-	1.13.11.57,1.13.11.8	ko:K04099,ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA,LigB
YYD3_k127_5531477_7	290398.Csal_0286	1.223e-94	319.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XIDD@135619|Oceanospirillales	135619|Oceanospirillales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_5531477_1	288000.BBta_2700	9.712e-172	549.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3JS0S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	ligI	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
YYD3_k127_5531477_4	1382303.JPOM01000001_gene2331	3.406e-132	429.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2KFMY@204458|Caulobacterales	204458|Caulobacterales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD3_k127_5531477_10	330084.JNYZ01000004_gene734	5.374e-90	300.0	28N0F@1|root,2ZB6V@2|Bacteria,2I31F@201174|Actinobacteria,4E391@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_5531477_9	1382306.JNIM01000001_gene3652	3.057e-90	308.0	COG0179@1|root,COG0179@2|Bacteria,2G6HH@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YYD3_k127_5531477_0	639030.JHVA01000001_gene603	3.565e-209	690.0	COG1629@1|root,COG1629@2|Bacteria,3Y2JN@57723|Acidobacteria,2JI08@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5531477_3	29581.BW37_01217	9.887e-136	445.0	COG2271@1|root,COG2271@2|Bacteria,1P24P@1224|Proteobacteria,2VIKS@28216|Betaproteobacteria,4791C@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Sugar (and other) transporter	pcaK	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
YYD3_k127_5531477_5	1218076.BAYB01000003_gene624	4.751e-116	381.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VZKQ@28216|Betaproteobacteria,1KFEU@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YYD3_k127_5531477_2	1097668.BYI23_C002820	1.57e-147	475.0	COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2VM1T@28216|Betaproteobacteria,1JZPS@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Gentisate 1,2-dioxygenase	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
YYD3_k127_5531477_6	391735.Veis_4205	8.036e-105	350.0	COG3473@1|root,COG3473@2|Bacteria,1N3F7@1224|Proteobacteria,2VH0K@28216|Betaproteobacteria,4A9KS@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Catalyzes the conversion of maleate to fumarate	maiA	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
YYD3_k127_5531477_12	1122137.AQXF01000001_gene3194	6.039e-37	161.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5537819_3	1196095.GAPWK_0247	8.376e-18	83.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
YYD3_k127_5537819_2	522306.CAP2UW1_4224	1.297e-34	140.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,1KQ3V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD3_k127_5537819_1	179408.Osc7112_4187	1.501e-77	270.0	COG1735@1|root,COG1735@2|Bacteria,1G4D4@1117|Cyanobacteria,1H9TU@1150|Oscillatoriales	1117|Cyanobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5537819_0	1038859.AXAU01000016_gene6832	2.602e-160	509.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3JRVC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_5562333_2	1121920.AUAU01000004_gene813	1.365e-64	234.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
YYD3_k127_5562333_1	215803.DB30_8025	7.428e-147	479.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
YYD3_k127_5562333_0	886293.Sinac_4683	1.054e-167	540.0	COG0457@1|root,COG0457@2|Bacteria	886293.Sinac_4683|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
YYD3_k127_5572578_10	1499967.BAYZ01000172_gene5780	9.591e-112	372.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD3_k127_5572578_32	643562.Daes_1977	7.746e-15	82.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,4321W@68525|delta/epsilon subdivisions,2WWR1@28221|Deltaproteobacteria,2M9G9@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
YYD3_k127_5572578_34	865861.AZSU01000002_gene3110	1.423e-05	57.0	COG0500@1|root,COG2226@2|Bacteria,1V6G6@1239|Firmicutes,24H8Z@186801|Clostridia	186801|Clostridia	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD3_k127_5572578_30	1163617.SCD_n01658	1.62e-25	116.0	COG0500@1|root,COG0500@2|Bacteria,1QYVI@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5572578_8	324602.Caur_1632	4.217e-131	435.0	COG1088@1|root,COG1088@2|Bacteria,2GA89@200795|Chloroflexi,3780Y@32061|Chloroflexia	32061|Chloroflexia	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_5572578_4	251229.Chro_4816	4.662e-158	508.0	COG0399@1|root,COG0399@2|Bacteria,1G5FI@1117|Cyanobacteria	1117|Cyanobacteria	E	COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_5572578_12	1173024.KI912149_gene4994	2.227e-95	323.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,1JM6G@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_5572578_6	489825.LYNGBM3L_52810	2.321e-153	491.0	COG2089@1|root,COG2089@2|Bacteria,1G3M1@1117|Cyanobacteria,1HFQ1@1150|Oscillatoriales	1117|Cyanobacteria	M	SPTR N-acetylneuraminic acid synthase, N-terminal domain protein	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
YYD3_k127_5572578_17	489825.LYNGBM3L_52770	9.812e-81	277.0	COG1028@1|root,COG1028@2|Bacteria,1GBR3@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD3_k127_5572578_2	1128421.JAGA01000003_gene3211	2.169e-190	610.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD3_k127_5572578_11	1128421.JAGA01000003_gene3212	5.235e-103	341.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
YYD3_k127_5572578_1	102232.GLO73106DRAFT_00026810	7.895e-221	708.0	COG0021@1|root,COG0021@2|Bacteria,1G4GX@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the transketolase family	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YYD3_k127_5572578_25	102232.GLO73106DRAFT_00034670	2.259e-54	201.0	COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YYD3_k127_5572578_3	489825.LYNGBM3L_15880	7.026e-186	605.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5572578_15	439235.Dalk_0708	2.701e-86	308.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
YYD3_k127_5572578_23	596151.DesfrDRAFT_4092	1.218e-56	211.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WN3F@28221|Deltaproteobacteria,2MAF8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_5572578_21	304371.MCP_0247	3.206e-65	236.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
YYD3_k127_5572578_26	644282.Deba_1050	7.369e-47	180.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,42W8F@68525|delta/epsilon subdivisions,2WRG3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YYD3_k127_5572578_19	232721.Ajs_2136	7.726e-73	263.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2VIKG@28216|Betaproteobacteria,4AC8S@80864|Comamonadaceae	28216|Betaproteobacteria	S	Fad dependent oxidoreductase	lhgO	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO
YYD3_k127_5572578_27	272844.PAB0789	1.608e-43	171.0	COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,243PG@183968|Thermococci	183968|Thermococci	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
YYD3_k127_5572578_7	1382356.JQMP01000004_gene206	1.36e-147	473.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,27XFT@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_5572578_18	696747.NIES39_D02560	5.58e-76	271.0	28KEP@1|root,2ZA0W@2|Bacteria,1G2EV@1117|Cyanobacteria,1H8V1@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5572578_29	573370.DMR_44350	4.507e-28	119.0	2CH0Y@1|root,3309M@2|Bacteria,1NF9M@1224|Proteobacteria,42VBP@68525|delta/epsilon subdivisions,2WRWS@28221|Deltaproteobacteria,2MB1U@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5572578_33	1121918.ARWE01000001_gene745	2.506e-14	79.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,42X36@68525|delta/epsilon subdivisions,2WSNU@28221|Deltaproteobacteria,43VPW@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5572578_5	1304872.JAGC01000003_gene3462	5.309e-154	498.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,2M82I@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YYD3_k127_5572578_20	537971.HCCG_01925	1.003e-71	257.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2YS4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
YYD3_k127_5572578_0	234267.Acid_3814	9.728e-231	745.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria	57723|Acidobacteria	K	chaperone-mediated protein folding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	TPR_8
YYD3_k127_5572578_22	1047013.AQSP01000138_gene1062	1.001e-58	219.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
YYD3_k127_5572578_9	671143.DAMO_2565	5.899e-116	378.0	COG2022@1|root,COG2022@2|Bacteria,2NQHA@2323|unclassified Bacteria	2|Bacteria	H	Thiazole biosynthesis protein ThiG	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
YYD3_k127_5572578_31	1248916.ANFY01000003_gene962	5.22e-15	78.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
YYD3_k127_5572578_24	96561.Dole_0148	8.523e-55	213.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
YYD3_k127_5572578_16	379066.GAU_0826	3.038e-86	292.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_5572578_13	379066.GAU_0825	1.263e-92	326.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
YYD3_k127_5572578_14	861299.J421_0393	4.378e-92	335.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0393|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5572767_1	1267535.KB906767_gene1290	2.381e-63	228.0	COG0697@1|root,COG0697@2|Bacteria,3Y570@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD3_k127_5572767_2	246197.MXAN_5348	1.064e-37	154.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD3_k127_5572767_0	234267.Acid_4491	1.074e-250	786.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YYD3_k127_5579274_6	485913.Krac_0963	2.057e-14	72.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi	200795|Chloroflexi	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_5579274_1	1120971.AUCA01000029_gene222	2.985e-123	406.0	COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,2793W@186823|Alicyclobacillaceae	91061|Bacilli	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	odhB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_5579274_0	479434.Sthe_2058	0.0	1039.0	COG0567@1|root,COG0567@2|Bacteria,2G638@200795|Chloroflexi,27XYT@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YYD3_k127_5579274_2	204669.Acid345_4036	9.787e-51	192.0	COG0561@1|root,COG0561@2|Bacteria,3Y4J5@57723|Acidobacteria,2JJB7@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
YYD3_k127_5579274_4	1500897.JQNA01000002_gene2973	1.243e-29	127.0	COG0627@1|root,COG0627@2|Bacteria,1NF5B@1224|Proteobacteria,2WGE5@28216|Betaproteobacteria,1KID6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_5579274_3	903818.KI912268_gene1800	1.777e-33	134.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YYD3_k127_5579274_5	1487953.JMKF01000059_gene4908	1.207e-21	102.0	COG0286@1|root,COG2865@1|root,COG0286@2|Bacteria,COG2865@2|Bacteria,1G15W@1117|Cyanobacteria,1HDDN@1150|Oscillatoriales	1117|Cyanobacteria	KT	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,Response_reg
YYD3_k127_5581069_6	1267535.KB906767_gene4866	8.969e-34	138.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3,DUF1566
YYD3_k127_5581069_1	1340493.JNIF01000003_gene1440	9.305e-182	593.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
YYD3_k127_5581069_10	1122604.JONR01000025_gene4602	1.304e-18	100.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
YYD3_k127_5581069_11	1244869.H261_23157	0.0004179	53.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
YYD3_k127_5581069_8	1278073.MYSTI_04845	8.421e-29	131.0	COG3386@1|root,COG3386@2|Bacteria,1RE3R@1224|Proteobacteria,42SFJ@68525|delta/epsilon subdivisions,2WPY7@28221|Deltaproteobacteria,2YV98@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5581069_2	1267535.KB906767_gene5108	9.767e-100	359.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria,2JITF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_5581069_5	1227739.Hsw_3898	4.967e-37	147.0	2EHJH@1|root,336RS@2|Bacteria,4NX01@976|Bacteroidetes,47SDR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5581069_0	452637.Oter_0831	1.677e-215	696.0	COG2366@1|root,COG2366@2|Bacteria	2|Bacteria	D	antibiotic biosynthetic process	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
YYD3_k127_5581069_3	1380394.JADL01000002_gene1538	9.633e-85	290.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2JPEG@204441|Rhodospirillales	204441|Rhodospirillales	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
YYD3_k127_5581069_7	1536774.H70357_09765	5.356e-32	139.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,4HB8E@91061|Bacilli,26T4I@186822|Paenibacillaceae	91061|Bacilli	E	Amino acid oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
YYD3_k127_5581069_4	1196323.ALKF01000184_gene3624	1.742e-60	217.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,26RWT@186822|Paenibacillaceae	91061|Bacilli	S	deacetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YYD3_k127_5581069_9	292459.STH1624	3.441e-27	112.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,25EPJ@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5594772_1	525903.Taci_1224	0.0005692	43.0	COG0358@1|root,COG0358@2|Bacteria,3TAFM@508458|Synergistetes	508458|Synergistetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YYD3_k127_5594772_0	861299.J421_4428	5.71e-132	432.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
YYD3_k127_5611500_0	204669.Acid345_3426	8.962e-187	602.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
YYD3_k127_5611500_6	671143.DAMO_1446	1.135e-53	197.0	COG0500@1|root,COG2226@2|Bacteria,2NPUA@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
YYD3_k127_5611500_13	414684.RC1_4003	3.036e-06	59.0	COG5338@1|root,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria,2U090@28211|Alphaproteobacteria,2JQS1@204441|Rhodospirillales	204441|Rhodospirillales	M	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
YYD3_k127_5611500_9	1499967.BAYZ01000121_gene3405	3.749e-42	168.0	COG1596@1|root,COG1596@2|Bacteria,2NPNM@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide export protein	-	-	-	ko:K01991,ko:K20988	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
YYD3_k127_5611500_1	378806.STAUR_6925	6.749e-98	333.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,43AHD@68525|delta/epsilon subdivisions,2X5XJ@28221|Deltaproteobacteria,2YXYK@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5611500_4	395963.Bind_0839	1.136e-56	213.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_5611500_7	163908.KB235896_gene3045	3.083e-53	205.0	28IMQ@1|root,2Z8N6@2|Bacteria,1G4IZ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5611500_11	1232410.KI421421_gene3605	7.3e-22	110.0	COG2244@1|root,COG2244@2|Bacteria,1NB5K@1224|Proteobacteria,43AXB@68525|delta/epsilon subdivisions,2X6BJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
YYD3_k127_5611500_5	649831.L083_7332	1.26e-56	216.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	waaD	-	2.4.1.56	ko:K00713,ko:K03280	ko00540,ko01100,map00540,map01100	M00080	R01996	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4,GT9	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5611500_2	1297742.A176_03398	1.884e-70	254.0	COG0438@1|root,COG0438@2|Bacteria,1P49U@1224|Proteobacteria,43921@68525|delta/epsilon subdivisions,2X47N@28221|Deltaproteobacteria,2YYFG@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
YYD3_k127_5611500_10	28072.Nos7524_0438	1.241e-27	126.0	COG0438@1|root,COG0438@2|Bacteria,1G6HW@1117|Cyanobacteria,1HMQ8@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5611500_8	163908.KB235896_gene3049	3.353e-51	197.0	COG0438@1|root,COG0438@2|Bacteria,1GK0E@1117|Cyanobacteria,1HT0E@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD3_k127_5611500_12	1121013.P873_00945	1.451e-12	79.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales	135614|Xanthomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
YYD3_k127_5611500_3	215803.DB30_3213	3.427e-69	241.0	COG4122@1|root,COG4122@2|Bacteria,1N96U@1224|Proteobacteria,42XTJ@68525|delta/epsilon subdivisions,2WTH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YYD3_k127_56160_13	553217.ENHAE0001_0099	0.0008657	51.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,3NJAK@468|Moraxellaceae	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,MLTD_N,SLT
YYD3_k127_56160_0	402777.KB235903_gene1681	9.318e-235	743.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD3_k127_56160_2	1267535.KB906767_gene1811	3.387e-127	424.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K03535,ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.1,2.A.1.14.7	-	-	MFS_1,Sugar_tr
YYD3_k127_56160_4	1122137.AQXF01000001_gene2828	5.31e-94	323.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_56160_8	1236959.BAMT01000005_gene49	8.703e-34	135.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,2KMQT@206350|Nitrosomonadales	206350|Nitrosomonadales	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
YYD3_k127_56160_5	443144.GM21_2031	4.917e-82	281.0	COG0500@1|root,COG2226@2|Bacteria,1R5UA@1224|Proteobacteria,42P7B@68525|delta/epsilon subdivisions,2WJSN@28221|Deltaproteobacteria,43SXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
YYD3_k127_56160_3	1210884.HG799466_gene12520	1.753e-111	371.0	COG1858@1|root,COG1858@2|Bacteria,2J2BZ@203682|Planctomycetes	203682|Planctomycetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
YYD3_k127_56160_11	1267533.KB906734_gene3979	3.778e-16	85.0	2A09E@1|root,30NCR@2|Bacteria,3Y8XP@57723|Acidobacteria,2JNU4@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_56160_12	405948.SACE_3359	3.361e-05	54.0	COG2755@1|root,COG2755@2|Bacteria,2GJUC@201174|Actinobacteria,4DYB1@85010|Pseudonocardiales	201174|Actinobacteria	E	Lysophospholipase L1-like esterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YYD3_k127_56160_7	330214.NIDE0317	2.318e-45	171.0	COG3663@1|root,COG3663@2|Bacteria	2|Bacteria	L	G/U mismatch-specific uracil-DNA glycosylase activity	mug	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.28,6.3.3.2	ko:K01934,ko:K03649	ko00670,ko01100,ko03410,map00670,map01100,map03410	-	R02301	RC00183	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD3_k127_56160_10	627192.SLG_09880	1.6e-16	90.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_56160_1	1144275.COCOR_02429	5.945e-130	445.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X2MT@28221|Deltaproteobacteria,2YTVU@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
YYD3_k127_56160_6	1340493.JNIF01000003_gene3859	6.272e-64	231.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_56160_9	1120963.KB894491_gene663	1.042e-24	115.0	COG0491@1|root,COG0491@2|Bacteria,1PBS8@1224|Proteobacteria,1RS4P@1236|Gammaproteobacteria,2Q09T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5617924_0	1500301.JQMF01000024_gene1983	1.471e-82	276.0	COG3832@1|root,COG3832@2|Bacteria,1RJKI@1224|Proteobacteria,2UAQG@28211|Alphaproteobacteria,4BCHX@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD3_k127_5617924_3	1469607.KK073768_gene840	2.301e-13	72.0	COG0500@1|root,COG0553@1|root,COG1061@1|root,COG0553@2|Bacteria,COG1061@2|Bacteria,COG2226@2|Bacteria,1GCH4@1117|Cyanobacteria	1117|Cyanobacteria	L	Probable Zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379,Methyltransf_8
YYD3_k127_5617924_1	1120949.KB903350_gene8348	1e-65	233.0	2DBYY@1|root,2ZBYF@2|Bacteria,2HZJA@201174|Actinobacteria,4DK06@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5617924_2	861299.J421_2288	4.666e-21	94.0	COG1028@1|root,COG1028@2|Bacteria	861299.J421_2288|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5628780_0	1267535.KB906767_gene2430	1.363e-165	542.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_5628780_4	204669.Acid345_4118	4.61e-62	240.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_5628780_2	234267.Acid_5036	6.439e-101	357.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
YYD3_k127_5628780_6	378806.STAUR_0350	1.257e-36	141.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,4382M@68525|delta/epsilon subdivisions,2X3CP@28221|Deltaproteobacteria,2YVFV@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
YYD3_k127_5628780_5	1472716.KBK24_0137205	2.734e-57	203.0	COG3832@1|root,COG3832@2|Bacteria,1RF9V@1224|Proteobacteria,2W2D0@28216|Betaproteobacteria,1KGAT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD3_k127_5628780_7	639030.JHVA01000001_gene1992	1.062e-18	94.0	2C0SZ@1|root,32R7J@2|Bacteria,3Y4ZA@57723|Acidobacteria,2JJII@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5628780_1	204669.Acid345_3588	4.9e-161	517.0	COG3503@1|root,COG3503@2|Bacteria,3Y6EK@57723|Acidobacteria,2JKNW@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
YYD3_k127_5628780_3	1040989.AWZU01000008_gene3682	5.36e-66	237.0	COG2863@1|root,COG2863@2|Bacteria,1QXNM@1224|Proteobacteria,2U2HM@28211|Alphaproteobacteria,3JZBZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YYD3_k127_5646013_9	1116369.KB890025_gene5107	4.152e-09	58.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,43I6G@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_5646013_6	1121346.KB899822_gene2902	1.494e-68	243.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_5646013_4	867903.ThesuDRAFT_02358	3.791e-80	280.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3WDHP@538999|Clostridiales incertae sedis	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_5646013_2	1120973.AQXL01000112_gene1044	5.677e-137	467.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,277VJ@186823|Alicyclobacillaceae	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YYD3_k127_5646013_5	1242864.D187_000933	1.049e-70	247.0	COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,43BX9@68525|delta/epsilon subdivisions,2X782@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
YYD3_k127_5646013_8	483219.LILAB_12330	3.464e-29	128.0	COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
YYD3_k127_5646013_7	1453501.JELR01000002_gene1450	2.99e-37	146.0	COG1595@1|root,COG1595@2|Bacteria,1N2DR@1224|Proteobacteria,1S7D6@1236|Gammaproteobacteria,467MI@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_5646013_3	485913.Krac_4715	1.423e-119	403.0	COG2272@1|root,COG2272@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
YYD3_k127_5646013_1	990285.RGCCGE502_01826	1.245e-147	471.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,4BBDC@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YYD3_k127_5646013_0	1123248.KB893326_gene1391	3.207e-162	512.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1INSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YYD3_k127_5653649_1	1267534.KB906760_gene1343	1.06e-26	126.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,Trans_reg_C
YYD3_k127_5653649_0	401053.AciPR4_3363	8.931e-61	240.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5663874_3	1267535.KB906767_gene4343	2.24e-48	186.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JM41@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_5663874_2	1379270.AUXF01000005_gene458	1.375e-72	261.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YYD3_k127_5663874_4	1379698.RBG1_1C00001G1362	1.168e-06	59.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
YYD3_k127_5663874_0	903818.KI912268_gene3150	2.121e-222	703.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YYD3_k127_5663874_1	204669.Acid345_1391	2.452e-112	370.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_5670841_12	671143.DAMO_2419	8.939e-70	246.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD3_k127_5670841_8	649747.HMPREF0083_05064	8.87e-110	368.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YYD3_k127_5670841_14	572477.Alvin_2983	1.282e-56	205.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1WY9P@135613|Chromatiales	135613|Chromatiales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YYD3_k127_5670841_15	264732.Moth_0890	2.259e-52	197.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,42EU9@68295|Thermoanaerobacterales	186801|Clostridia	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
YYD3_k127_5670841_3	401526.TcarDRAFT_0104	8.579e-147	484.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD3_k127_5670841_7	713587.THITH_00175	2.471e-110	367.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD3_k127_5670841_0	1297742.A176_03413	1.815e-177	565.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD3_k127_5670841_17	525909.Afer_0742	2.665e-44	175.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4CN35@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5670841_19	521098.Aaci_0273	2.962e-38	157.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,4I2BX@91061|Bacilli,27A0Y@186823|Alicyclobacillaceae	91061|Bacilli	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5670841_18	1379698.RBG1_1C00001G1894	1.763e-38	156.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
YYD3_k127_5670841_13	903818.KI912269_gene293	1.005e-57	218.0	COG0265@1|root,COG0265@2|Bacteria,3Y3HE@57723|Acidobacteria	2|Bacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_5670841_10	204669.Acid345_1265	6.592e-92	314.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria,2JJTZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5670841_9	1499967.BAYZ01000055_gene4868	5.244e-107	363.0	COG0438@1|root,COG0438@2|Bacteria,2NP1P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5670841_5	1499967.BAYZ01000017_gene6221	3.16e-125	424.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
YYD3_k127_5670841_2	1403819.BATR01000002_gene72	8.253e-147	470.0	COG0451@1|root,COG0451@2|Bacteria,46S80@74201|Verrucomicrobia,2ITWW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
YYD3_k127_5670841_21	1499967.BAYZ01000084_gene3991	3.379e-30	126.0	COG0558@1|root,COG0558@2|Bacteria,2NRJN@2323|unclassified Bacteria	2|Bacteria	I	CDP-alcohol phosphatidyltransferase	MA20_28295	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YYD3_k127_5670841_23	1227349.C170_16695	4.968e-07	62.0	COG1361@1|root,COG4655@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4655@2|Bacteria,COG4932@2|Bacteria,1VX9E@1239|Firmicutes,4HIIK@91061|Bacilli,26SBE@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,MucBP,SLH
YYD3_k127_5670841_24	1159870.KB907784_gene1648	0.0004015	53.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,3T868@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
YYD3_k127_5670841_6	1121430.JMLG01000009_gene476	9.326e-114	380.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YYD3_k127_5670841_16	1320556.AVBP01000019_gene1206	9.818e-47	185.0	COG0477@1|root,COG2814@2|Bacteria,1MUBP@1224|Proteobacteria,2TQVH@28211|Alphaproteobacteria,43HEA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	mdtG	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,Sugar_tr
YYD3_k127_5670841_4	204669.Acid345_0609	2.343e-128	419.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
YYD3_k127_5670841_1	1379698.RBG1_1C00001G0527	2.153e-158	512.0	COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD3_k127_5670841_22	1267535.KB906767_gene1512	3.996e-12	75.0	COG0500@1|root,COG0500@2|Bacteria,3Y5HU@57723|Acidobacteria	57723|Acidobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5670841_20	204669.Acid345_1716	1.109e-30	129.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria,2JJ4E@204432|Acidobacteriia	57723|Acidobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD3_k127_5670841_11	246194.CHY_2199	1.95e-87	295.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD3_k127_5673826_6	452637.Oter_0832	2.436e-06	52.0	COG0035@1|root,COG0035@2|Bacteria,46ST2@74201|Verrucomicrobia,3K7WA@414999|Opitutae	414999|Opitutae	F	uracil phosphoribosyltransferase	-	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
YYD3_k127_5673826_5	234267.Acid_1287	5.846e-14	76.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_5673826_4	761193.Runsl_0518	5.503e-45	169.0	2DMP1@1|root,32SS8@2|Bacteria,4NQY9@976|Bacteroidetes,47QNE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
YYD3_k127_5673826_7	194439.CT1907	3.421e-05	49.0	COG4980@1|root,COG4980@2|Bacteria,1FEAF@1090|Chlorobi	1090|Chlorobi	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
YYD3_k127_5673826_3	269799.Gmet_2541	3.215e-46	181.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43TRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YYD3_k127_5673826_2	204669.Acid345_2891	8.661e-69	243.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD3_k127_5673826_1	861299.J421_3477	2.802e-74	257.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YYD3_k127_5673826_0	401053.AciPR4_1799	1.839e-287	896.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YYD3_k127_5678562_1	316057.RPD_3110	2.745e-17	87.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3JRZ3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_5678562_3	671143.DAMO_0741	0.0001969	49.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
YYD3_k127_5678562_2	639030.JHVA01000001_gene2502	3.291e-11	70.0	COG5485@1|root,COG5485@2|Bacteria,3Y5WS@57723|Acidobacteria,2JNYM@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD3_k127_5678562_0	1123503.KB908057_gene2609	1.895e-17	88.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2KEY1@204458|Caulobacterales	204458|Caulobacterales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
YYD3_k127_5683439_6	1121440.AUMA01000003_gene2969	4.763e-39	146.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2M7Z9@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD3_k127_5683439_9	1385515.N791_10115	0.0003273	52.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832,ko:K07126	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
YYD3_k127_5683439_8	246969.TAM4_499	5.659e-14	84.0	COG0515@1|root,arCOG00372@1|root,arCOG03264@1|root,arCOG00372@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2XWYZ@28890|Euryarchaeota,2437Z@183968|Thermococci	183968|Thermococci	T	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD3_k127_5683439_2	589865.DaAHT2_1307	2.803e-94	323.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MHM1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YYD3_k127_5683439_4	644282.Deba_2110	3.057e-70	244.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YYD3_k127_5683439_1	234267.Acid_6976	7.359e-142	473.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5683439_3	1476583.DEIPH_ctg011orf0097	3.12e-82	283.0	COG2084@1|root,COG2084@2|Bacteria,1WKEB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
YYD3_k127_5683439_7	1112204.GPOL_c44650	2.931e-15	79.0	COG1359@1|root,COG1359@2|Bacteria,2GSE1@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
YYD3_k127_5683439_0	986075.CathTA2_0959	1.785e-268	848.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YYD3_k127_5683439_5	1267535.KB906767_gene913	2.193e-68	255.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD3_k127_5690025_0	401053.AciPR4_3363	1.61e-43	183.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5710930_7	862908.BMS_2196	7.273e-11	68.0	2CAZH@1|root,2Z7RU@2|Bacteria,1N3AE@1224|Proteobacteria,42UBH@68525|delta/epsilon subdivisions,2MT2C@213481|Bdellovibrionales,2WQ56@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
YYD3_k127_5710930_3	555793.WSK_3236	1.372e-27	116.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5710930_4	1088721.NSU_2823	1.774e-21	105.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5710930_10	709986.Deima_3072	4.201e-06	57.0	COG1426@1|root,COG1426@2|Bacteria,1WI06@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PEGA domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25,PEGA
YYD3_k127_5710930_1	1211115.ALIQ01000238_gene3256	1.206e-75	266.0	COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2TZR6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_5710930_0	1142394.PSMK_17680	2.784e-130	432.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	HD,HD_5
YYD3_k127_5710930_8	1122134.KB893650_gene224	4.211e-10	70.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,PKD,P_proprotein,Peptidase_S8
YYD3_k127_5710930_6	1423814.HMPREF0549_0257	1.539e-15	78.0	COG3549@1|root,COG3549@2|Bacteria,1VHBH@1239|Firmicutes,4IGFI@91061|Bacilli,3F87C@33958|Lactobacillaceae	91061|Bacilli	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
YYD3_k127_5719017_1	304371.MCP_0247	3.447e-35	142.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
YYD3_k127_5719017_0	479434.Sthe_0904	1.407e-44	176.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5719017_2	666686.B1NLA3E_19985	1.123e-06	62.0	COG1705@1|root,COG4193@1|root,COG1705@2|Bacteria,COG4193@2|Bacteria,1UT0U@1239|Firmicutes,4HB90@91061|Bacilli,1ZEHX@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3,SLH
YYD3_k127_574940_2	234267.Acid_5856	3.717e-100	336.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_574940_0	1340493.JNIF01000003_gene4390	2.861e-193	611.0	COG2133@1|root,COG2133@2|Bacteria,3Y36R@57723|Acidobacteria	57723|Acidobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_574940_4	251221.35214127	2.165e-40	154.0	COG3744@1|root,COG3744@2|Bacteria,1G89C@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_574940_6	395495.Lcho_1566	2.226e-18	87.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281,PhdYeFM_antitox
YYD3_k127_574940_3	266117.Rxyl_1776	5.314e-68	243.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
YYD3_k127_574940_5	864051.BurJ1DRAFT_2043	1.134e-33	135.0	COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,2VT15@28216|Betaproteobacteria,1KMD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
YYD3_k127_574940_1	234267.Acid_2557	3.459e-190	612.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_5753055_1	1122164.JHWF01000005_gene166	1.712e-33	137.0	COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,1RPRS@1236|Gammaproteobacteria,1JDIB@118969|Legionellales	118969|Legionellales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
YYD3_k127_5753055_4	697282.Mettu_0367	7.506e-20	96.0	2E6QP@1|root,331AW@2|Bacteria,1N83E@1224|Proteobacteria,1SDRG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5753055_2	215803.DB30_1378	8.285e-32	130.0	COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria,432Z6@68525|delta/epsilon subdivisions,2WXKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YYD3_k127_5753055_6	1173263.Syn7502_00208	0.0001725	52.0	COG2227@1|root,COG2227@2|Bacteria,1G0TK@1117|Cyanobacteria,1GZNY@1129|Synechococcus	1117|Cyanobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_31
YYD3_k127_5753055_5	76114.ebA2182	1.629e-05	48.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2VJJ4@28216|Betaproteobacteria,2KVCR@206389|Rhodocyclales	206389|Rhodocyclales	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
YYD3_k127_5753055_0	118161.KB235922_gene4854	2.583e-34	135.0	COG0454@1|root,COG0454@2|Bacteria,1GQTG@1117|Cyanobacteria	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_5753055_3	1449080.JQMV01000003_gene544	2.278e-25	108.0	COG0624@1|root,COG0624@2|Bacteria,1WIJT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_5765827_4	1123242.JH636435_gene2917	3.397e-30	130.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
YYD3_k127_5765827_2	1160718.SU9_28741	5.223e-73	264.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD3_k127_5765827_1	234267.Acid_5927	1.399e-81	295.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_5765827_0	234267.Acid_5921	2.141e-211	696.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
YYD3_k127_5765827_3	234267.Acid_1440	3.125e-45	175.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
YYD3_k127_5765827_6	382464.ABSI01000012_gene2201	1.332e-05	55.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
YYD3_k127_5765827_7	1192868.CAIU01000040_gene4440	0.0008989	42.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YYD3_k127_5765827_5	502558.EGYY_03930	1.469e-20	96.0	COG3478@1|root,COG3478@2|Bacteria,2GYSQ@201174|Actinobacteria,4CWS9@84998|Coriobacteriia	84998|Coriobacteriia	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_577121_0	1267535.KB906767_gene3867	5.329e-245	767.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N
YYD3_k127_577121_3	1382359.JIAL01000001_gene1321	6.663e-95	319.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
YYD3_k127_577121_5	1424334.W822_07565	7.351e-71	253.0	COG2267@1|root,COG2267@2|Bacteria,1RE00@1224|Proteobacteria,2WFBI@28216|Betaproteobacteria,3T9DZ@506|Alcaligenaceae	1224|Proteobacteria	I	Twin-arginine translocation pathway signal protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_577121_1	682795.AciX8_3558	2.654e-144	473.0	COG1506@1|root,COG1506@2|Bacteria,3Y6MJ@57723|Acidobacteria,2JMBK@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_577121_4	99598.Cal7507_6086	2.867e-84	282.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
YYD3_k127_577121_2	566461.SSFG_07676	5.585e-103	347.0	COG1960@1|root,COG1960@2|Bacteria,2GMKM@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
YYD3_k127_577121_6	401053.AciPR4_3363	2.043e-16	92.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_581108_1	886293.Sinac_1156	5.566e-149	499.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
YYD3_k127_581108_2	926566.Terro_2596	2.732e-148	488.0	COG0457@1|root,COG0457@2|Bacteria,3Y3HT@57723|Acidobacteria,2JHSD@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_581108_5	379066.GAU_0527	8.249e-14	84.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_581108_6	682795.AciX8_2156	3.893e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
YYD3_k127_581108_4	251229.Chro_5034	1.635e-36	157.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,3VHP9@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_581108_3	234267.Acid_2032	2.804e-112	377.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_581108_0	234267.Acid_5827	8.447e-246	785.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_581108_7	530564.Psta_3545	1.733e-07	57.0	COG2331@1|root,COG2331@2|Bacteria,2J18U@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YYD3_k127_581108_8	502025.Hoch_1719	3.382e-05	55.0	2DYFY@1|root,349IC@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_582470_2	398767.Glov_1480	5.037e-12	70.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_582470_0	1121430.JMLG01000005_gene750	5.83e-73	259.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,260UC@186807|Peptococcaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
YYD3_k127_582470_1	1267535.KB906767_gene5406	8.517e-21	95.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
YYD3_k127_5828022_3	1173264.KI913949_gene1115	1.95e-56	207.0	COG0739@1|root,COG1404@1|root,COG4257@1|root,COG0739@2|Bacteria,COG1404@2|Bacteria,COG4257@2|Bacteria,1G7B0@1117|Cyanobacteria,1HBXD@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD3_k127_5828022_1	1449063.JMLS01000019_gene5666	1.598e-109	372.0	COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,4HBN4@91061|Bacilli,26UWH@186822|Paenibacillaceae	91061|Bacilli	E	Flavin containing amine oxidoreductase	iaaM	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YYD3_k127_5828022_6	929562.Emtol_4114	5.261e-17	92.0	COG4870@1|root,COG4870@2|Bacteria,4NQK4@976|Bacteroidetes,47XFW@768503|Cytophagia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
YYD3_k127_5828022_4	395965.Msil_0929	2.293e-19	91.0	COG5513@1|root,COG5513@2|Bacteria	2|Bacteria	G	serine-type aminopeptidase activity	-	-	-	ko:K02030,ko:K14475	ko05143,map05143	M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	Inhibitor_I42
YYD3_k127_5828022_2	1210884.HG799466_gene12570	6.599e-61	219.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5828022_0	234267.Acid_5749	1.336e-186	623.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_5828022_5	314265.R2601_15627	1e-18	93.0	COG2333@1|root,COG2333@2|Bacteria,1PZYY@1224|Proteobacteria,2UJ6W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5833228_0	234267.Acid_3488	1.424e-58	214.0	2CEJ5@1|root,2Z7RK@2|Bacteria,3Y4QU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5833228_1	272134.KB731324_gene5642	8.703e-53	195.0	COG4974@1|root,COG4974@2|Bacteria,1G6WZ@1117|Cyanobacteria,1HHMF@1150|Oscillatoriales	1117|Cyanobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YYD3_k127_5833228_2	1385510.N781_16220	1.512e-19	95.0	2CK1P@1|root,2ZAJN@2|Bacteria,1UR1W@1239|Firmicutes,4HK7T@91061|Bacilli	91061|Bacilli	S	Psort location Cytoplasmic, score	M1-1036	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5833228_5	392499.Swit_2219	6.531e-13	80.0	COG1961@1|root,COG1961@2|Bacteria,1MV0C@1224|Proteobacteria,2TTJT@28211|Alphaproteobacteria,2K2KR@204457|Sphingomonadales	204457|Sphingomonadales	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
YYD3_k127_5833228_4	1123278.KB893422_gene1616	5.797e-14	78.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YYD3_k127_5833228_3	1040989.AWZU01000023_gene4843	6.068e-16	82.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
YYD3_k127_5853412_10	1340493.JNIF01000003_gene1293	3.818e-44	176.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
YYD3_k127_5853412_12	1449049.JONW01000009_gene4446	2.895e-36	151.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2UI5V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
YYD3_k127_5853412_6	326427.Cagg_2452	2.142e-108	361.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,37710@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
YYD3_k127_5853412_4	243231.GSU3318	3.258e-126	421.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
YYD3_k127_5853412_13	234267.Acid_4018	5.423e-35	156.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y34Z@57723|Acidobacteria	57723|Acidobacteria	M	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
YYD3_k127_5853412_11	1267534.KB906755_gene3911	2.211e-39	154.0	COG0484@1|root,COG0484@2|Bacteria,3Y8AR@57723|Acidobacteria	57723|Acidobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
YYD3_k127_5853412_7	1211115.ALIQ01000238_gene3256	2.651e-95	321.0	COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2TZR6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_5853412_14	876269.ARWA01000001_gene3105	1.781e-30	129.0	COG1359@1|root,COG1359@2|Bacteria,1PS55@1224|Proteobacteria,2V4C6@28211|Alphaproteobacteria,3NCI7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
YYD3_k127_5853412_1	1123248.KB893323_gene1603	7.901e-222	699.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,1IUJ0@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
YYD3_k127_5853412_8	1380394.JADL01000001_gene3047	1.061e-67	233.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,2JS0C@204441|Rhodospirillales	204441|Rhodospirillales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
YYD3_k127_5853412_15	1000565.METUNv1_00412	1.234e-25	110.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,2VVHG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YYD3_k127_5853412_3	1210884.HG799464_gene10383	5.568e-144	463.0	COG1023@1|root,COG1023@2|Bacteria,2IYCD@203682|Planctomycetes	203682|Planctomycetes	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
YYD3_k127_5853412_2	211165.AJLN01000096_gene5033	1.803e-184	587.0	COG0364@1|root,COG0364@2|Bacteria,1GI0D@1117|Cyanobacteria,1JJHW@1189|Stigonemataceae	1117|Cyanobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	G6PD_C,G6PD_N
YYD3_k127_5853412_9	1340493.JNIF01000004_gene918	2.385e-49	198.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
YYD3_k127_5853412_5	234267.Acid_2032	4.58e-115	385.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_5853412_0	234267.Acid_5827	1.186e-225	726.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_5853412_16	326427.Cagg_0357	3.569e-09	68.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	32061|Chloroflexia	NU	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_10,TPR_12,TPR_16,TPR_7
YYD3_k127_5862916_0	1137269.AZWL01000005_gene2298	2.539e-171	550.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria	201174|Actinobacteria	F	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
YYD3_k127_588714_0	234267.Acid_4431	1.014e-200	661.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_588714_2	1267533.KB906738_gene2330	4.601e-56	213.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD3_k127_588714_1	234267.Acid_7677	7.321e-68	237.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_588714_3	497964.CfE428DRAFT_4864	5.179e-55	203.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5890968_6	234267.Acid_3749	6.332e-08	63.0	29B3X@1|root,2ZY2J@2|Bacteria,3Y92X@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
YYD3_k127_5890968_2	234267.Acid_3750	2.632e-82	283.0	COG1131@1|root,COG1131@2|Bacteria,3Y50U@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_5890968_3	234267.Acid_3751	1.771e-36	143.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	ytrA	-	-	ko:K07978,ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
YYD3_k127_5890968_5	136993.KB900627_gene392	2.456e-24	115.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5890968_1	1121920.AUAU01000007_gene506	5.086e-136	445.0	COG0477@1|root,COG2814@2|Bacteria,3Y6YQ@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_5890968_4	247633.GP2143_17796	3.956e-35	147.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5890968_0	1278073.MYSTI_05376	1.217e-177	571.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,43C8U@68525|delta/epsilon subdivisions,2X7J6@28221|Deltaproteobacteria,2Z3H1@29|Myxococcales	28221|Deltaproteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
YYD3_k127_5890968_7	765911.Thivi_2038	0.0001615	53.0	COG1716@1|root,COG2304@1|root,COG1716@2|Bacteria,COG2304@2|Bacteria,1RBT3@1224|Proteobacteria,1S3HI@1236|Gammaproteobacteria,1X0AU@135613|Chromatiales	135613|Chromatiales	T	PFAM von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5909584_1	1122176.KB903554_gene3842	1.756e-50	199.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,4NM1E@976|Bacteroidetes,1IWA5@117747|Sphingobacteriia	976|Bacteroidetes	MP	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,OmpA
YYD3_k127_5909584_2	1125971.ASJB01000083_gene1823	1.304e-36	149.0	COG0600@1|root,COG0600@2|Bacteria,2ICUJ@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YYD3_k127_5909584_0	1118054.CAGW01000081_gene2667	1.629e-57	220.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,26RHF@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YYD3_k127_5909584_4	1089550.ATTH01000001_gene1633	3.295e-08	64.0	2EDTI@1|root,337NU@2|Bacteria,4P32V@976|Bacteroidetes,1FK0A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5909584_3	794903.OPIT5_05780	1.754e-12	76.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YYD3_k127_591363_0	234267.Acid_3680	1.95e-54	204.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_591363_1	234267.Acid_4494	9.775e-11	63.0	COG1595@1|root,COG1595@2|Bacteria,3Y7YB@57723|Acidobacteria	2|Bacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
YYD3_k127_5963715_6	880073.Calab_1008	4.197e-25	110.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
YYD3_k127_5963715_0	234267.Acid_7220	1.169e-171	549.0	COG2010@1|root,COG2010@2|Bacteria,3Y650@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3,Paired_CXXCH_1
YYD3_k127_5963715_1	1304885.AUEY01000019_gene1163	3.625e-114	379.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
YYD3_k127_5963715_8	555793.WSK_2000	4.365e-07	57.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5963715_2	1235457.C404_01565	2.532e-87	298.0	COG2162@1|root,COG2162@2|Bacteria,1RDF3@1224|Proteobacteria,2VT30@28216|Betaproteobacteria,1K0C4@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Belongs to the arylamine N-acetyltransferase family	nhoA	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
YYD3_k127_5963715_4	234267.Acid_1337	4.239e-37	152.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
YYD3_k127_5963715_5	379066.GAU_2664	1.074e-28	119.0	2EAHU@1|root,334M0@2|Bacteria,1ZV5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5963715_3	379066.GAU_2663	1.693e-41	161.0	COG0346@1|root,COG0346@2|Bacteria,1ZU6Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_5963715_9	247633.GP2143_13056	0.0009183	48.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6006882_8	404589.Anae109_4095	3.931e-81	287.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,42SFA@68525|delta/epsilon subdivisions,2WUV2@28221|Deltaproteobacteria,2YVKJ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD3_k127_6006882_0	404589.Anae109_4094	0.0	1171.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YYD3_k127_6006882_19	1088721.NSU_2813	1.337e-06	61.0	2FIXR@1|root,34ANN@2|Bacteria,1NNY2@1224|Proteobacteria,2UMAG@28211|Alphaproteobacteria,2K886@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
YYD3_k127_6006882_7	349521.HCH_03730	5.922e-83	283.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1XJFM@135619|Oceanospirillales	135619|Oceanospirillales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
YYD3_k127_6006882_15	1090319.KE386571_gene1420	5.817e-30	134.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,2U7U4@28211|Alphaproteobacteria,2K7J3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6006882_5	1163617.SCD_n02012	7.342e-109	366.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_6006882_10	999541.bgla_2g23630	3.496e-61	221.0	COG3842@1|root,COG3842@2|Bacteria,1NYPP@1224|Proteobacteria,2VQ7J@28216|Betaproteobacteria,1K358@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran
YYD3_k127_6006882_13	1392489.JPOL01000003_gene106	4.269e-44	181.0	COG1178@1|root,COG1178@2|Bacteria,4NEG1@976|Bacteroidetes,1I0BE@117743|Flavobacteriia	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
YYD3_k127_6006882_6	765912.Thimo_1760	2.229e-99	338.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1WWM0@135613|Chromatiales	135613|Chromatiales	P	extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
YYD3_k127_6006882_11	234267.Acid_6894	1.513e-51	190.0	COG3848@1|root,COG3848@2|Bacteria,3Y79R@57723|Acidobacteria	57723|Acidobacteria	T	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YYD3_k127_6006882_16	589865.DaAHT2_0849	3.316e-29	136.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,43C3N@68525|delta/epsilon subdivisions,2X7EC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_6006882_3	936455.KI421499_gene213	1.348e-169	546.0	COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
YYD3_k127_6006882_1	234267.Acid_5827	2.284e-208	677.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_6006882_4	234267.Acid_2032	4.107e-119	398.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_6006882_9	886293.Sinac_1155	1.015e-69	258.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
YYD3_k127_6006882_2	1038860.AXAP01000018_gene3108	6.229e-184	594.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_6006882_14	215803.DB30_1747	1.382e-38	166.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YYD3_k127_6006882_12	234267.Acid_3773	1.481e-45	179.0	COG2372@1|root,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	-	-	3.2.1.20	ko:K01187,ko:K16915	ko00052,ko00500,ko01100,ko02010,map00052,map00500,map01100,map02010	M00246	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02000	-	GH31	-	Big_5
YYD3_k127_6006882_17	886293.Sinac_1863	2.112e-28	131.0	COG1225@1|root,COG1225@2|Bacteria,2IXKB@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_6006882_18	1236959.BAMT01000015_gene2850	2.897e-23	110.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6026534_9	1267533.KB906733_gene3215	7.251e-45	184.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_6026534_20	1340493.JNIF01000003_gene2122	1.424e-13	76.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6026534_5	204669.Acid345_4596	7.722e-91	312.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
YYD3_k127_6026534_16	1123057.P872_13075	7.942e-27	117.0	COG4122@1|root,COG4122@2|Bacteria,4PBU1@976|Bacteroidetes,47WBZ@768503|Cytophagia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
YYD3_k127_6026534_3	479434.Sthe_2327	2.878e-113	380.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YYD3_k127_6026534_1	330214.NIDE1215	2.597e-132	430.0	COG0407@1|root,COG0407@2|Bacteria,3J0C3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
YYD3_k127_6026534_19	1521187.JPIM01000012_gene1667	6.017e-14	78.0	COG0745@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,EAL,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_6026534_12	1173020.Cha6605_0378	3.337e-38	150.0	COG0398@1|root,COG0398@2|Bacteria,1G3PG@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YYD3_k127_6026534_7	1123242.JH636434_gene3809	4.183e-50	182.0	COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes	203682|Planctomycetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
YYD3_k127_6026534_18	234267.Acid_4033	1.018e-15	90.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6026534_13	204669.Acid345_1477	1.064e-37	154.0	COG0583@1|root,COG0583@2|Bacteria,3Y4EH@57723|Acidobacteria,2JJ60@204432|Acidobacteriia	204432|Acidobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD3_k127_6026534_4	706587.Desti_1588	1.068e-101	342.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	cfr9IM	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
YYD3_k127_6026534_14	1003200.AXXA_03589	8.989e-37	154.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,3T1YA@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
YYD3_k127_6026534_17	349161.Dred_1117	1.144e-19	102.0	COG3058@1|root,COG3058@2|Bacteria,1VD22@1239|Firmicutes,24P6T@186801|Clostridia,262GU@186807|Peptococcaceae	186801|Clostridia	O	Necessary for formate dehydrogenase activity	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
YYD3_k127_6026534_0	204669.Acid345_3349	2.365e-135	455.0	COG0297@1|root,COG0297@2|Bacteria,3Y3IH@57723|Acidobacteria,2JHNU@204432|Acidobacteriia	204432|Acidobacteriia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YYD3_k127_6026534_15	1304275.C41B8_00770	7.939e-34	132.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291	Thioredoxin
YYD3_k127_6026534_2	330214.NIDE1127	6.751e-119	390.0	COG0492@1|root,COG0492@2|Bacteria,3J0M0@40117|Nitrospirae	40117|Nitrospirae	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
YYD3_k127_6026534_8	1121920.AUAU01000026_gene1478	1.208e-46	172.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_6026534_10	1382359.JIAL01000001_gene1066	1.711e-44	168.0	COG2318@1|root,COG2318@2|Bacteria,3Y4AI@57723|Acidobacteria,2JKRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
YYD3_k127_6026534_6	1007096.BAGW01000014_gene1118	3.026e-59	212.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2N6EJ@216572|Oscillospiraceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YYD3_k127_6026534_11	269799.Gmet_0873	7.278e-44	165.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YYD3_k127_6047039_1	1379698.RBG1_1C00001G1364	1.856e-74	269.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YYD3_k127_6047039_0	1047013.AQSP01000140_gene2537	4.384e-83	291.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_6047039_2	278963.ATWD01000001_gene3318	3.847e-29	136.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria,2JI94@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_6056546_4	1267534.KB906759_gene1881	2.626e-19	99.0	COG4219@1|root,COG4219@2|Bacteria,3Y6SV@57723|Acidobacteria,2JKBD@204432|Acidobacteriia	204432|Acidobacteriia	KT	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
YYD3_k127_6056546_0	1278073.MYSTI_02531	1.794e-308	959.0	COG1858@1|root,COG1858@2|Bacteria,1MWAT@1224|Proteobacteria,42Y6Q@68525|delta/epsilon subdivisions,2WU96@28221|Deltaproteobacteria,2YVFI@29|Myxococcales	28221|Deltaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
YYD3_k127_6056546_3	379066.GAU_0069	3.952e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_6056546_2	1183438.GKIL_3395	6.022e-186	612.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
YYD3_k127_6056546_1	234267.Acid_3938	4.958e-188	619.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6056794_2	234267.Acid_4393	1.375e-145	490.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6056794_0	234267.Acid_7696	3.352e-305	946.0	COG1166@1|root,COG1166@2|Bacteria,3Y449@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YYD3_k127_6056794_5	391625.PPSIR1_04398	1.299e-29	126.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
YYD3_k127_6056794_3	1338011.BD94_2259	4.431e-112	380.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1HX2J@117743|Flavobacteriia,34QI9@308865|Elizabethkingia	976|Bacteroidetes	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
YYD3_k127_6056794_1	983917.RGE_40040	5.537e-189	617.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2VYC3@28216|Betaproteobacteria,1KP31@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	oligoendopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
YYD3_k127_6056794_4	247633.GP2143_17796	6.227e-33	139.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_605840_2	1210884.HG799473_gene14952	1.252e-54	196.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2IY3H@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
YYD3_k127_605840_0	298655.KI912266_gene277	7.173e-78	267.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4EWG8@85013|Frankiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YYD3_k127_605840_1	1042377.AFPJ01000032_gene2732	7.88e-58	206.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria,46AJ1@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD3_k127_605840_3	358396.C445_00290	6.34e-37	146.0	COG4635@1|root,arCOG00524@2157|Archaea,2XWSS@28890|Euryarchaeota,23V70@183963|Halobacteria	183963|Halobacteria	C	COG4635 Flavodoxin	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
YYD3_k127_605840_4	1122201.AUAZ01000056_gene35	2.557e-05	46.0	2AWWV@1|root,31NUD@2|Bacteria,1QPF3@1224|Proteobacteria,1SJ55@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6063130_2	1379270.AUXF01000002_gene1600	4.275e-12	70.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6063130_1	1267533.KB906736_gene1347	2.062e-35	138.0	COG1695@1|root,COG1695@2|Bacteria,3Y55J@57723|Acidobacteria,2JJQ9@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_6063130_0	1267533.KB906734_gene4002	3.774e-49	189.0	COG0577@1|root,COG0577@2|Bacteria	1267533.KB906734_gene4002|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6064543_0	204669.Acid345_0770	2.13e-126	422.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
YYD3_k127_6065714_1	1379270.AUXF01000001_gene2420	1.994e-68	237.0	COG2080@1|root,COG2080@2|Bacteria,1ZTHW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
YYD3_k127_6065714_0	1340493.JNIF01000004_gene24	4.922e-278	874.0	COG1529@1|root,COG1529@2|Bacteria,3Y77V@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
YYD3_k127_6065714_2	401053.AciPR4_3363	5.105e-41	172.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6072513_7	1267535.KB906767_gene1620	2.772e-06	51.0	COG0577@1|root,COG0577@2|Bacteria,3Y41Z@57723|Acidobacteria,2JI5N@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6072513_6	204669.Acid345_0913	2.458e-16	94.0	COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6072513_2	861299.J421_3227	2.102e-173	553.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YYD3_k127_6072513_1	234267.Acid_6472	4.812e-218	688.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria	57723|Acidobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YYD3_k127_6072513_4	525904.Tter_1673	3.834e-55	200.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
YYD3_k127_6072513_5	404589.Anae109_1476	1.447e-37	154.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_6072513_0	269800.Tfu_1936	0.0	1108.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
YYD3_k127_6072513_3	469371.Tbis_3424	9.885e-74	261.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD3_k127_6073491_4	1340493.JNIF01000003_gene2543	1.053e-77	271.0	COG1409@1|root,COG1409@2|Bacteria,3Y6AF@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_6073491_5	398720.MED217_02520	1.084e-29	132.0	28JNX@1|root,2Z9F0@2|Bacteria,4NJS0@976|Bacteroidetes,1HYGX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6073491_7	1245475.ANAE01000164_gene2341	5.417e-14	76.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4EHVJ@85012|Streptosporangiales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,F5_F8_type_C,Inhibitor_I9,PA,Peptidase_S8,fn3_5
YYD3_k127_6073491_0	1128421.JAGA01000002_gene1344	1.955e-260	822.0	COG1404@1|root,COG1404@2|Bacteria,2NQYY@2323|unclassified Bacteria	2|Bacteria	O	PA domain	vpr	GO:0005575,GO:0005576	-	ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FlgD_ig,Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5
YYD3_k127_6073491_2	1183438.GKIL_3693	3.438e-127	423.0	COG3569@1|root,COG3569@2|Bacteria,1G2R6@1117|Cyanobacteria	1117|Cyanobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
YYD3_k127_6073491_3	1267533.KB906738_gene2436	1.056e-106	377.0	COG1629@1|root,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_6073491_1	243233.MCA0609	8.865e-202	644.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XENZ@135618|Methylococcales	135618|Methylococcales	S	ABC transporter C-terminal domain	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YYD3_k127_6073491_9	234267.Acid_3898	1.148e-05	59.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
YYD3_k127_6083819_4	204669.Acid345_3233	1.801e-168	543.0	COG0606@1|root,COG0606@2|Bacteria,3Y3JA@57723|Acidobacteria,2JI3F@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YYD3_k127_6083819_17	1122621.ATZA01000009_gene288	5.205e-08	66.0	28HMX@1|root,2Z7WB@2|Bacteria,4NFY2@976|Bacteroidetes,1IPRK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6083819_10	1321778.HMPREF1982_03041	5.784e-75	260.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_6083819_0	1267535.KB906767_gene2959	0.0	1027.0	COG3661@1|root,COG3661@2|Bacteria,3Y2TM@57723|Acidobacteria,2JHXT@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 67 C-terminus	-	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
YYD3_k127_6083819_16	595460.RRSWK_02095	1.866e-09	63.0	COG4146@1|root,COG4146@2|Bacteria,2J29I@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
YYD3_k127_6083819_3	926569.ANT_05060	3.391e-175	556.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YYD3_k127_6083819_2	59538.XP_005979070.1	7.638e-200	628.0	COG4948@1|root,2QRKX@2759|Eukaryota,38HCT@33154|Opisthokonta,3BYW6@33208|Metazoa	33208|Metazoa	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YYD3_k127_6083819_6	1396141.BATP01000023_gene619	7.397e-124	417.0	COG1070@1|root,COG1070@2|Bacteria,46UPD@74201|Verrucomicrobia,2IV4A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
YYD3_k127_6083819_7	204669.Acid345_0549	4.19e-102	354.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria,2JHZB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YYD3_k127_6083819_5	349161.Dred_1305	4.982e-158	518.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,260WN@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM acetaldehyde dehydrogenase (acetylating)	-	-	1.2.1.10	ko:K00132	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD3_k127_6083819_12	1123312.KB904574_gene187	1.796e-39	148.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4HM6R@91061|Bacilli	91061|Bacilli	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
YYD3_k127_6083819_9	243231.GSU1784	1.604e-85	297.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,42SJG@68525|delta/epsilon subdivisions,2WP9K@28221|Deltaproteobacteria,43T1M@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	pulF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
YYD3_k127_6083819_1	204669.Acid345_1576	1.243e-232	733.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
YYD3_k127_6083819_14	1382359.JIAL01000001_gene1457	2.454e-23	112.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
YYD3_k127_6083819_18	243231.GSU1781	1.106e-06	60.0	COG3166@1|root,COG3166@2|Bacteria,1Q5NW@1224|Proteobacteria,431IV@68525|delta/epsilon subdivisions,2WWZG@28221|Deltaproteobacteria,43VK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM Fimbrial assembly family protein	pulN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
YYD3_k127_6083819_20	316067.Geob_2646	0.0001671	51.0	2DXN2@1|root,345N1@2|Bacteria,1Q1PJ@1224|Proteobacteria,4319I@68525|delta/epsilon subdivisions,2WWAH@28221|Deltaproteobacteria,43VEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pilus assembly protein, PilO	pulO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
YYD3_k127_6083819_19	204669.Acid345_1579	0.0001019	51.0	2C8FF@1|root,333TN@2|Bacteria,3Y5GA@57723|Acidobacteria,2JJYB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6083819_8	1047013.AQSP01000036_gene1385	1.788e-98	351.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
YYD3_k127_6083819_11	639030.JHVA01000001_gene638	2.201e-43	166.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
YYD3_k127_6083819_13	1121920.AUAU01000026_gene1477	1.177e-28	121.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
YYD3_k127_6083819_21	439235.Dalk_0482	0.0008169	51.0	COG1018@1|root,COG4447@1|root,COG1018@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	-
YYD3_k127_6098299_6	1444309.JAQG01000068_gene1757	5.632e-25	105.0	COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,26RQG@186822|Paenibacillaceae	91061|Bacilli	O	L-lysine 6-monooxygenase (NADPH-requiring)	trxB3	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
YYD3_k127_6098299_5	926550.CLDAP_10210	4.301e-136	449.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartokinase family	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
YYD3_k127_6098299_2	886293.Sinac_3438	8.49e-178	581.0	COG4122@1|root,COG4122@2|Bacteria,2IXSM@203682|Planctomycetes	203682|Planctomycetes	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6098299_3	234267.Acid_5749	1.812e-174	580.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6098299_1	671143.DAMO_0866	7.386e-236	737.0	COG0493@1|root,COG0493@2|Bacteria,2NNUI@2323|unclassified Bacteria	2|Bacteria	E	Flavin containing amine oxidoreductase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
YYD3_k127_6098299_0	525904.Tter_0474	0.0	2046.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YYD3_k127_6098299_4	1267535.KB906767_gene4766	3.099e-156	496.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
YYD3_k127_6109669_0	247633.GP2143_17791	9.054e-72	251.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6109669_3	1255043.TVNIR_1089	2.2e-20	94.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,1SJ4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
YYD3_k127_6109669_5	1123060.JONP01000029_gene3643	4.023e-05	50.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria,2JZTG@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_6109669_1	1472418.BBJC01000004_gene1788	1.538e-71	258.0	2CBAE@1|root,31814@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6109669_2	234267.Acid_4431	1.769e-49	195.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6113091_1	204669.Acid345_2388	9.501e-77	271.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Z6@57723|Acidobacteria,2JIQG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6113091_3	761193.Runsl_0449	4.35e-08	64.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,47P6A@768503|Cytophagia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
YYD3_k127_6113091_0	1267535.KB906767_gene4476	5.626e-77	264.0	COG1082@1|root,COG1082@2|Bacteria,3Y69B@57723|Acidobacteria,2JM08@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_6113091_2	639030.JHVA01000001_gene2683	4.31e-14	72.0	COG1082@1|root,COG1082@2|Bacteria,3Y69B@57723|Acidobacteria,2JM08@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_6136880_0	204669.Acid345_1690	1.319e-261	816.0	COG0457@1|root,COG0457@2|Bacteria,3Y3MH@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_6136880_5	1151119.KB895497_gene3408	1.803e-52	207.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD3_k127_6136880_1	350058.Mvan_1084	8.556e-123	416.0	COG2267@1|root,COG2267@2|Bacteria,2I9JC@201174|Actinobacteria	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
YYD3_k127_6136880_4	589873.EP13_13630	1.581e-58	219.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6136880_6	1210884.HG799465_gene11339	3.829e-49	181.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YYD3_k127_6136880_2	861299.J421_0282	2.72e-89	324.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6136880_7	1340493.JNIF01000003_gene1551	1.133e-36	148.0	COG2318@1|root,COG2318@2|Bacteria,3Y503@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_6136880_3	1123248.KB893325_gene1223	2.79e-76	278.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NIKG@976|Bacteroidetes,1IWUH@117747|Sphingobacteriia	976|Bacteroidetes	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
YYD3_k127_6144073_1	348824.LPU83_3304	2.508e-122	397.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,4B7GV@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	epoxide hydrolase	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
YYD3_k127_6144073_0	1172179.AUKV01000054_gene106	1.032e-141	456.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria	201174|Actinobacteria	K	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
YYD3_k127_6144539_3	247633.GP2143_17796	2.273e-11	66.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6144539_2	266779.Meso_2898	1.507e-12	74.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6144539_4	627192.SLG_09880	1.734e-08	67.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6144539_0	234267.Acid_2075	1.106e-186	599.0	COG3356@1|root,COG3356@2|Bacteria,3Y5I7@57723|Acidobacteria	57723|Acidobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
YYD3_k127_6144539_1	1247963.JPHU01000015_gene1155	3.892e-44	167.0	COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2TUU5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_6147196_1	316274.Haur_0219	8.309e-89	313.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD3_k127_6147196_2	1123234.AUKI01000011_gene1439	6.862e-63	222.0	28I5V@1|root,2Z891@2|Bacteria,4NF4U@976|Bacteroidetes,1HZRH@117743|Flavobacteriia	976|Bacteroidetes	G	Cellulase N-terminal ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
YYD3_k127_6147196_0	234267.Acid_1966	2.561e-175	572.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_6149827_9	1267535.KB906767_gene3784	7.483e-09	64.0	2EJFZ@1|root,32FNH@2|Bacteria,3Y8XH@57723|Acidobacteria,2JNW0@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6149827_7	1101195.Meth11DRAFT_1464	1.378e-21	102.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6149827_0	1089545.KB913037_gene1118	1.136e-179	572.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4EA5C@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YYD3_k127_6149827_1	1123508.JH636445_gene6659	4.428e-133	432.0	COG1131@1|root,COG1131@2|Bacteria,2IYFJ@203682|Planctomycetes	203682|Planctomycetes	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_6149827_2	1123508.JH636445_gene6658	5.185e-117	381.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YYD3_k127_6149827_10	1267535.KB906767_gene429	7.624e-08	63.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,3Y62Q@57723|Acidobacteria,2JM1D@204432|Acidobacteriia	204432|Acidobacteriia	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
YYD3_k127_6149827_11	682795.AciX8_1061	2.473e-07	61.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Y0@57723|Acidobacteria,2JIYU@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6149827_3	234267.Acid_4819	1.09e-58	228.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,3Y8M9@57723|Acidobacteria	57723|Acidobacteria	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56,TonB_C
YYD3_k127_6149827_4	886293.Sinac_6279	6.133e-41	154.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_6149827_5	926569.ANT_02620	1.803e-31	132.0	29AZZ@1|root,2ZXYX@2|Bacteria,2G8ZX@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6149827_6	1340493.JNIF01000003_gene1440	3.541e-25	104.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
YYD3_k127_6166541_11	1047013.AQSP01000028_gene2076	1.075e-27	124.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
YYD3_k127_6166541_5	1121468.AUBR01000026_gene2950	1.834e-66	232.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,42G0W@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
YYD3_k127_6166541_2	1121468.AUBR01000026_gene2951	2.132e-116	390.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,42EY2@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD3_k127_6166541_1	269799.Gmet_1770	1.166e-136	449.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YYD3_k127_6166541_6	1173264.KI913949_gene3883	6.766e-58	205.0	COG0454@1|root,COG0456@2|Bacteria,1G5VH@1117|Cyanobacteria,1HB58@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_6166541_12	351016.RAZWK3B_13899	3.649e-15	87.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
YYD3_k127_6166541_3	1232410.KI421416_gene2647	4.166e-70	254.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,43T7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
YYD3_k127_6166541_9	861299.J421_2147	1.31e-43	164.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_6166541_0	479434.Sthe_2955	4.36e-189	598.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_6166541_7	1125863.JAFN01000001_gene535	4.816e-51	195.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_6166541_4	1125863.JAFN01000001_gene533	6.753e-69	242.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2X6Y1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_6166541_10	1267535.KB906767_gene1757	1.245e-38	164.0	COG1538@1|root,COG1538@2|Bacteria,3Y2R2@57723|Acidobacteria,2JIWN@204432|Acidobacteriia	204432|Acidobacteriia	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD3_k127_6166541_8	1131462.DCF50_p1457	2.805e-48	178.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YYD3_k127_6173747_1	234267.Acid_6847	2.992e-144	483.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6173747_8	452637.Oter_1495	3.262e-15	78.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia,3K8CC@414999|Opitutae	414999|Opitutae	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YYD3_k127_6173747_7	1210884.HG799469_gene14083	1.696e-22	103.0	COG0494@1|root,COG0494@2|Bacteria,2J0TH@203682|Planctomycetes	203682|Planctomycetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_6173747_0	861299.J421_2451	2.923e-152	500.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_6173747_5	391625.PPSIR1_32487	4.015e-38	158.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
YYD3_k127_6173747_6	1445613.JALM01000005_gene1186	8.465e-30	123.0	COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_6173747_2	164757.Mjls_0699	1.468e-78	272.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,237IR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
YYD3_k127_6173747_4	1449063.JMLS01000003_gene1833	6.039e-69	243.0	COG3576@1|root,COG3576@2|Bacteria,1UZ02@1239|Firmicutes,4HEN8@91061|Bacilli,26R91@186822|Paenibacillaceae	91061|Bacilli	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
YYD3_k127_6173747_3	1038859.AXAU01000001_gene3393	6.59e-74	255.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U0ZD@28211|Alphaproteobacteria,3JY8Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.52	ko:K22213	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_2
YYD3_k127_6177659_2	439235.Dalk_1526	5.797e-75	288.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
YYD3_k127_6177659_3	478741.JAFS01000001_gene1434	1.305e-70	274.0	COG2204@1|root,COG2204@2|Bacteria,46YV1@74201|Verrucomicrobia,37G08@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_6177659_0	1120960.ATXG01000016_gene1472	2.263e-154	493.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4FKJ2@85023|Microbacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
YYD3_k127_6177659_5	1340493.JNIF01000004_gene141	7.132e-33	138.0	COG3861@1|root,COG3861@2|Bacteria	2|Bacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
YYD3_k127_6177659_1	1123368.AUIS01000044_gene15	2.047e-110	378.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YYD3_k127_6177659_4	107635.AZUO01000001_gene3356	3.272e-52	195.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,36X8N@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
YYD3_k127_6195626_0	234267.Acid_5749	1.466e-196	640.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6195626_1	1340493.JNIF01000004_gene597	1.978e-21	107.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_6232742_4	926566.Terro_2784	5.952e-13	76.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_6232742_2	204669.Acid345_1209	3.659e-42	156.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria,2JJSS@204432|Acidobacteriia	204432|Acidobacteriia	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
YYD3_k127_6232742_3	234267.Acid_4371	1.334e-23	100.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
YYD3_k127_6232742_0	370438.PTH_2540	1.496e-125	414.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YYD3_k127_6232742_1	204669.Acid345_1211	3.567e-87	303.0	COG0621@1|root,COG0621@2|Bacteria,3Y41R@57723|Acidobacteria,2JKPA@204432|Acidobacteriia	204432|Acidobacteriia	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
YYD3_k127_6232742_5	1379270.AUXF01000003_gene3385	2.92e-05	51.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
YYD3_k127_6233173_12	926560.KE387027_gene263	1.265e-08	57.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YYD3_k127_6233173_11	485913.Krac_4939	1.137e-11	65.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
YYD3_k127_6233173_6	234267.Acid_5195	4.68e-57	209.0	2EHG8@1|root,33B84@2|Bacteria,3Y808@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6233173_2	404589.Anae109_1600	1.042e-117	388.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,Cupin_6,HTH_18
YYD3_k127_6233173_10	1340493.JNIF01000003_gene1849	2.238e-17	93.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_6233173_14	1382359.JIAL01000001_gene2820	5.562e-07	63.0	2EXAB@1|root,33QKZ@2|Bacteria,3Y6WS@57723|Acidobacteria,2JMCR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6233173_9	234267.Acid_3420	6.575e-24	117.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria	2|Bacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
YYD3_k127_6233173_4	857087.Metme_0626	6.472e-89	299.0	COG3193@1|root,COG3193@2|Bacteria,1R215@1224|Proteobacteria,1S4R1@1236|Gammaproteobacteria,1XF9H@135618|Methylococcales	135618|Methylococcales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
YYD3_k127_6233173_0	234267.Acid_6265	2.027e-250	799.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_6233173_5	1210884.HG799465_gene12265	1.567e-76	272.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_6233173_3	1191523.MROS_2662	1.602e-95	323.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YYD3_k127_6233173_1	234267.Acid_2721	5.717e-125	422.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YYD3_k127_6233173_13	56107.Cylst_2790	3.844e-08	55.0	COG2346@1|root,COG2346@2|Bacteria,1G7GU@1117|Cyanobacteria,1HQ0F@1161|Nostocales	1117|Cyanobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YYD3_k127_6233173_8	234267.Acid_1440	8.438e-27	125.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
YYD3_k127_6233173_7	1185876.BN8_03339	4.221e-38	147.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,47P3T@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
YYD3_k127_6253639_0	251221.35211322	4.91e-139	452.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
YYD3_k127_6254038_8	1270193.JARP01000007_gene340	1.245e-24	107.0	COG2060@1|root,COG2060@2|Bacteria,4NF2G@976|Bacteroidetes,1HZ90@117743|Flavobacteriia,2NTR5@237|Flavobacterium	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
YYD3_k127_6254038_5	1038858.AXBA01000016_gene1973	6.818e-65	229.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,3EYZ3@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	Response regulator receiver	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_6254038_2	1267535.KB906767_gene3888	1.14e-75	273.0	COG0642@1|root,COG2205@2|Bacteria,3Y2W3@57723|Acidobacteria,2JIDP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
YYD3_k127_6254038_1	1449126.JQKL01000021_gene89	1.159e-110	374.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,267US@186813|unclassified Clostridiales	186801|Clostridia	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
YYD3_k127_6254038_4	1157490.EL26_22520	2.426e-67	236.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,27APN@186823|Alicyclobacillaceae	91061|Bacilli	P	TrkA-C domain	ktrA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
YYD3_k127_6254038_10	1033730.CAHG01000017_gene2449	2.799e-10	64.0	28PUR@1|root,2ZCFM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6254038_0	234267.Acid_6747	1.393e-244	766.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD3_k127_6254038_7	706587.Desti_2581	6.341e-34	134.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MS7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YYD3_k127_6254038_6	323097.Nham_2535	2.898e-64	226.0	COG0664@1|root,COG0664@2|Bacteria,1MV7G@1224|Proteobacteria,2U1I4@28211|Alphaproteobacteria,3JUCQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
YYD3_k127_6254038_3	1267535.KB906767_gene2921	2.836e-70	245.0	COG0664@1|root,COG0664@2|Bacteria,3Y69P@57723|Acidobacteria	57723|Acidobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
YYD3_k127_6254038_9	1112214.AHIS01000054_gene2558	6.98e-15	75.0	COG1278@1|root,COG1278@2|Bacteria,1QRMX@1224|Proteobacteria,2V17U@28211|Alphaproteobacteria,2KB7U@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock protein domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
YYD3_k127_628977_0	64471.sync_2679	5.377e-150	491.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_628977_1	278963.ATWD01000001_gene1278	1.363e-36	149.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
YYD3_k127_6298603_3	1082931.KKY_2582	2.305e-34	136.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_6298603_1	1082931.KKY_2582	2.113e-204	653.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_6298603_0	1267535.KB906767_gene656	5.37e-211	665.0	COG1032@1|root,COG1032@2|Bacteria,3Y2FN@57723|Acidobacteria,2JI6W@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_6298603_2	1128912.GMES_2046	4.528e-158	509.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,468S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	SGL
YYD3_k127_6299568_1	649638.Trad_0140	1.471e-61	220.0	COG0546@1|root,COG0546@2|Bacteria,1WMMK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YYD3_k127_6299568_2	639030.JHVA01000001_gene3136	9.105e-39	149.0	2C5VR@1|root,32CJG@2|Bacteria,3Y4V1@57723|Acidobacteria,2JJM5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299568_4	67332.FM21_06920	9.785e-14	76.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
YYD3_k127_6299568_7	234267.Acid_4948	8.044e-06	52.0	COG5649@1|root,COG5649@2|Bacteria,3Y94P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299568_5	1403819.BATR01000004_gene133	3.807e-11	70.0	COG2259@1|root,COG2259@2|Bacteria,46WDH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299568_6	234267.Acid_5847	1.226e-07	54.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6299731_9	682795.AciX8_3291	8.218e-05	50.0	COG4974@1|root,COG4974@2|Bacteria,3Y5GN@57723|Acidobacteria,2JJXR@204432|Acidobacteriia	204432|Acidobacteriia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YYD3_k127_6299731_5	1198114.AciX9_2028	2.603e-25	114.0	COG4974@1|root,COG4974@2|Bacteria,3Y5GN@57723|Acidobacteria,2JJXR@204432|Acidobacteriia	204432|Acidobacteriia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YYD3_k127_6299731_8	748280.NH8B_1148	9.603e-06	54.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299731_6	1267534.KB906756_gene712	1.567e-15	81.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299731_0	234267.Acid_3938	5.219e-199	653.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6299731_3	1120951.AUBG01000002_gene1247	1.212e-77	274.0	COG3409@1|root,COG3409@2|Bacteria,4P2U6@976|Bacteroidetes	976|Bacteroidetes	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299731_4	1469607.KK073768_gene900	2.362e-52	210.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1HIE5@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_6299731_2	1267534.KB906754_gene2942	2.849e-106	373.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,3Y4XJ@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9
YYD3_k127_6299731_1	243090.RB4667	5.007e-116	389.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6299731_7	1349767.GJA_3694	5.945e-06	49.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria,474ZB@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
YYD3_k127_6325114_3	670292.JH26_04745	1.864e-37	150.0	COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,2U91T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YYD3_k127_6325114_2	1121904.ARBP01000013_gene313	1.657e-38	160.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,47JVD@768503|Cytophagia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_6325114_0	864051.BurJ1DRAFT_2034	6.251e-128	430.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,1KJN0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_6325114_1	123899.JPQP01000001_gene1633	2.066e-104	342.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,3T2TT@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
YYD3_k127_6330223_3	158500.BV97_01286	3.241e-71	253.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,2KATS@204457|Sphingomonadales	204457|Sphingomonadales	S	Beta-lactamase superfamily domain	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_6330223_1	472759.Nhal_2902	1.818e-192	612.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
YYD3_k127_6330223_2	880073.Calab_1318	1.331e-131	454.0	COG0508@1|root,COG0508@2|Bacteria,2NP69@2323|unclassified Bacteria	2|Bacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	aceF	GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_6330223_0	204669.Acid345_2792	0.0	1376.0	COG2609@1|root,COG2609@2|Bacteria,3Y2M3@57723|Acidobacteria,2JHM5@204432|Acidobacteriia	204432|Acidobacteriia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YYD3_k127_6330223_4	483219.LILAB_25925	2.24e-68	261.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,42SMW@68525|delta/epsilon subdivisions,2WPP1@28221|Deltaproteobacteria,2YUYP@29|Myxococcales	28221|Deltaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD3_k127_6343029_7	1121939.L861_22705	2.388e-37	142.0	2CZ4M@1|root,32T5I@2|Bacteria,1N344@1224|Proteobacteria,1SRM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6343029_5	324602.Caur_2444	7.324e-42	158.0	COG2764@1|root,COG2764@2|Bacteria,2GB45@200795|Chloroflexi,377VR@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6343029_2	317013.NY99_16300	2.639e-60	213.0	2DN6S@1|root,32VV5@2|Bacteria,1NFSJ@1224|Proteobacteria,1SCH4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4265)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4265
YYD3_k127_6343029_1	1304878.AUGD01000010_gene4425	5.332e-63	224.0	COG0546@1|root,COG0546@2|Bacteria,1REXF@1224|Proteobacteria,2VG24@28211|Alphaproteobacteria,3JSJQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	HAD-hyrolase-like	MA20_36165	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD3_k127_6343029_8	1394178.AWOO02000024_gene5654	1.423e-14	84.0	2A3AC@1|root,30RSD@2|Bacteria,2IKHP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6343029_4	1128421.JAGA01000001_gene2135	1.595e-47	179.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.11.1,5.2.1.8	ko:K01802,ko:K03767,ko:K03768,ko:K12132	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03110,ko04147	-	-	-	Pro_isomerase
YYD3_k127_6343029_0	682795.AciX8_3558	1.374e-137	453.0	COG1506@1|root,COG1506@2|Bacteria,3Y6MJ@57723|Acidobacteria,2JMBK@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_6343029_3	1123256.KB907943_gene455	3.735e-53	192.0	COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S69D@1236|Gammaproteobacteria,1XC2C@135614|Xanthomonadales	135614|Xanthomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
YYD3_k127_6343029_9	1068978.AMETH_0190	2.301e-08	61.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
YYD3_k127_6343029_6	517418.Ctha_2104	4.463e-40	151.0	COG1085@1|root,COG1085@2|Bacteria,1FEPC@1090|Chlorobi	1090|Chlorobi	C	Domain of unknown function (DUF4921)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4921
YYD3_k127_637418_1	1267535.KB906767_gene1072	9.892e-148	474.0	COG0175@1|root,COG0175@2|Bacteria,3Y36I@57723|Acidobacteria,2JIQ5@204432|Acidobacteriia	204432|Acidobacteriia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YYD3_k127_637418_2	1267535.KB906767_gene1073	4.069e-146	484.0	COG2895@1|root,COG2895@2|Bacteria,3Y3AW@57723|Acidobacteria,2JI68@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
YYD3_k127_637418_5	1382359.JIAL01000001_gene2887	9.291e-75	257.0	COG0175@1|root,COG0175@2|Bacteria,3Y337@57723|Acidobacteria,2JI99@204432|Acidobacteriia	204432|Acidobacteriia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YYD3_k127_637418_4	710696.Intca_2186	3.104e-82	286.0	2BRPH@1|root,32KP4@2|Bacteria,2H2UK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_637418_6	234267.Acid_4171	2.758e-37	153.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_637418_3	627192.SLG_26300	3.507e-96	325.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_637418_0	240015.ACP_0313	5.502e-204	642.0	COG3508@1|root,COG3508@2|Bacteria,3Y38R@57723|Acidobacteria,2JHM4@204432|Acidobacteriia	204432|Acidobacteriia	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
YYD3_k127_6377365_0	1163407.UU7_09910	1.656e-109	377.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1X431@135614|Xanthomonadales	135614|Xanthomonadales	S	type VI secretion protein	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
YYD3_k127_6377365_1	314278.NB231_12224	1.129e-100	346.0	COG0631@1|root,COG3913@1|root,COG0631@2|Bacteria,COG3913@2|Bacteria,1QFVW@1224|Proteobacteria,1RSPG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	type VI secretion-associated protein, BMA_A0400 family	-	-	-	ko:K11890	ko02025,map02025	-	-	-	ko00000,ko00001,ko02044	-	-	-	DUF2094
YYD3_k127_6377365_4	530564.Psta_1830	1.21e-43	173.0	COG3515@1|root,COG3515@2|Bacteria,2J0E6@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion-associated protein, ImpA family	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
YYD3_k127_6377365_3	62928.azo3895	1.797e-87	290.0	COG3516@1|root,COG3516@2|Bacteria,1RAZQ@1224|Proteobacteria,2VQ4P@28216|Betaproteobacteria,2KZTV@206389|Rhodocyclales	206389|Rhodocyclales	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
YYD3_k127_6377365_2	62928.azo3896	2.277e-93	308.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,2VKCP@28216|Betaproteobacteria,2KUA6@206389|Rhodocyclales	206389|Rhodocyclales	S	This family consists of a number of uncharacterised bacterial proteins. The function of this family is	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
YYD3_k127_6411221_16	1380390.JIAT01000010_gene4038	6.439e-15	76.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4CS3P@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6411221_2	1121033.AUCF01000021_gene2889	1.392e-184	587.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,2JQ2N@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD3_k127_6411221_12	272134.KB731324_gene2628	1.275e-30	125.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YYD3_k127_6411221_17	1242864.D187_002996	3.429e-10	65.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2YXFE@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
YYD3_k127_6411221_3	204669.Acid345_1269	4.176e-166	530.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_6411221_8	102125.Xen7305DRAFT_00044210	3.869e-61	223.0	28J65@1|root,30UIF@2|Bacteria,1GFWZ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6411221_18	452637.Oter_1641	5.738e-05	49.0	2CCSR@1|root,32RWC@2|Bacteria,46WYJ@74201|Verrucomicrobia,3K9ZP@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
YYD3_k127_6411221_6	1242864.D187_006882	1.375e-139	479.0	COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_6411221_10	1267533.KB906733_gene3356	1.557e-42	158.0	COG1695@1|root,COG1695@2|Bacteria,3Y8BI@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_6411221_14	1101195.Meth11DRAFT_1444	7.673e-16	84.0	2BUP9@1|root,32Q08@2|Bacteria,1PJNM@1224|Proteobacteria,2W82A@28216|Betaproteobacteria,2KNEM@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6411221_13	1340493.JNIF01000003_gene2121	5.762e-30	124.0	2CBAE@1|root,32S20@2|Bacteria,3Y93Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6411221_5	1267535.KB906767_gene3695	3.513e-150	506.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6411221_4	861299.J421_1205	6.235e-158	515.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD3	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
YYD3_k127_6411221_1	861299.J421_1204	1.728e-214	678.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD3_k127_6411221_0	204669.Acid345_1270	8.028e-285	885.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
YYD3_k127_6411221_7	204669.Acid345_1271	1.6e-137	454.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
YYD3_k127_6411221_11	234267.Acid_3837	3.822e-42	174.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_6411221_15	234267.Acid_1525	8.562e-16	92.0	COG4932@1|root,COG4932@2|Bacteria,3Y53F@57723|Acidobacteria	57723|Acidobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6411221_9	234267.Acid_3837	5.098e-52	205.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_6413979_1	1121920.AUAU01000030_gene2713	4.096e-22	100.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6413979_0	1173026.Glo7428_2548	6.893e-141	476.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9
YYD3_k127_6413979_2	1353531.AZNX01000014_gene3200	2.039e-10	64.0	2E6PF@1|root,3319T@2|Bacteria,1NBEJ@1224|Proteobacteria,2UG6V@28211|Alphaproteobacteria,4BJJY@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of Unknown function (DUF2604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2604
YYD3_k127_642585_1	379066.GAU_3321	6.795e-62	222.0	COG3836@1|root,COG3836@2|Bacteria,1ZV3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YYD3_k127_642585_0	1040989.AWZU01000035_gene1773	6.336e-113	379.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,3JRFB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb,TAT_signal
YYD3_k127_642585_4	795666.MW7_0686	6.161e-39	153.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2VIQV@28216|Betaproteobacteria,1K6FN@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
YYD3_k127_642585_2	1267534.KB906754_gene3106	8.064e-60	226.0	COG1228@1|root,COG1228@2|Bacteria,3Y539@57723|Acidobacteria,2JKT2@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_642585_5	627192.SLG_26300	8.321e-19	99.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_642585_3	1122604.JONR01000015_gene125	1.948e-40	165.0	COG0154@1|root,COG0154@2|Bacteria	2|Bacteria	J	amidase activity	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,SLH
YYD3_k127_6427690_0	1267533.KB906736_gene1146	7.262e-263	833.0	COG0577@1|root,COG0577@2|Bacteria,3Y41Z@57723|Acidobacteria,2JI5N@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_642944_0	522306.CAP2UW1_1835	1.042e-159	513.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2VKYS@28216|Betaproteobacteria,1KR3R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Inorganic ion transport and metabolism	ybhI	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
YYD3_k127_642944_3	522306.CAP2UW1_1836	8.954e-31	128.0	2CG45@1|root,33GFC@2|Bacteria,1NKZR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_642944_4	204669.Acid345_1452	8.605e-16	83.0	2DTV5@1|root,33MT0@2|Bacteria,3Y5UW@57723|Acidobacteria,2JNBS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_642944_2	1537715.JQFJ01000002_gene2265	2.857e-40	163.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,2K4IM@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_642944_5	627192.SLG_09880	2.36e-11	74.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_642944_1	379066.GAU_0953	1.682e-40	155.0	2BBQ7@1|root,3258A@2|Bacteria,1ZUVG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6505399_1	204669.Acid345_4118	6.15e-91	310.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_6505399_0	1242864.D187_008994	0.0	1214.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YYD3_k127_6505399_2	1122217.KB899568_gene798	4.333e-10	72.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD3_k127_6509444_3	234267.Acid_3526	1.656e-25	109.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_6509444_2	234267.Acid_7393	8.086e-36	146.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_6509444_0	1267534.KB906758_gene2318	4.211e-206	653.0	COG0671@1|root,COG0671@2|Bacteria,3Y7V9@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD3_k127_6509444_1	1267534.KB906758_gene2319	3.257e-86	294.0	28K2C@1|root,2Z9RQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6525796_0	1961.JOAK01000022_gene7055	6.877e-55	209.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
YYD3_k127_6525796_1	1248916.ANFY01000004_gene1771	1.75e-51	192.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,2KD4R@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
YYD3_k127_6527371_4	195250.CM001776_gene568	5.875e-57	201.0	COG0443@1|root,COG0443@2|Bacteria,1G1BJ@1117|Cyanobacteria,1GYQP@1129|Synechococcus	1117|Cyanobacteria	O	Heat shock 70 kDa protein	dnaK2	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YYD3_k127_6527371_5	76114.ebA2569	3.115e-54	199.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2VV97@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
YYD3_k127_6527371_0	1122915.AUGY01000039_gene1653	6.563e-112	372.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YYD3_k127_6527371_3	1268622.AVS7_02705	7.116e-62	225.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VKIQ@28216|Betaproteobacteria,4AJAG@80864|Comamonadaceae	28216|Betaproteobacteria	U	AAA domain	exeA2	-	-	ko:K02450,ko:K12283	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
YYD3_k127_6527371_2	234267.Acid_5500	2.041e-85	295.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	HemolysinCabind,Pro_isomerase
YYD3_k127_6527371_7	383372.Rcas_0058	1.625e-07	56.0	2A42D@1|root,30SM6@2|Bacteria,2GAFV@200795|Chloroflexi,375ZW@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6527371_1	1040983.AXAE01000018_gene5942	5.05e-96	327.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
YYD3_k127_6527371_6	485913.Krac_8660	1.917e-35	141.0	COG0756@1|root,COG0756@2|Bacteria	2|Bacteria	F	dUTP diphosphatase activity	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iYO844.BSU17660	dUTPase
YYD3_k127_6527520_13	1037409.BJ6T_40350	9.487e-25	110.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JUB5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YYD3_k127_6527520_14	1038862.KB893852_gene6725	1.235e-22	108.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JUB5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YYD3_k127_6527520_2	1217718.ALOU01000098_gene4274	2.758e-147	481.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2VN2I@28216|Betaproteobacteria,1K659@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Peptidase family M28	cgp	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YYD3_k127_6527520_8	1116369.KB890024_gene2824	1.031e-69	242.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,2UTR4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_6527520_10	247633.GP2143_18126	7.297e-62	225.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6527520_9	316067.Geob_2601	9.155e-67	238.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,437BB@68525|delta/epsilon subdivisions,2X2G7@28221|Deltaproteobacteria,43V98@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YYD3_k127_6527520_0	1340493.JNIF01000003_gene1819	0.0	1251.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
YYD3_k127_6527520_4	1254432.SCE1572_26500	8.598e-109	372.0	COG0642@1|root,COG0745@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
YYD3_k127_6527520_11	56110.Oscil6304_3208	7.116e-56	207.0	COG1776@1|root,COG1776@2|Bacteria,1G9M7@1117|Cyanobacteria,1HHRB@1150|Oscillatoriales	1117|Cyanobacteria	NT	CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
YYD3_k127_6527520_12	1173022.Cri9333_3528	1.554e-34	137.0	COG0745@1|root,COG0745@2|Bacteria,1G9E7@1117|Cyanobacteria,1HD4Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
YYD3_k127_6527520_3	1173028.ANKO01000214_gene6271	2.501e-136	446.0	COG2201@1|root,COG2201@2|Bacteria,1G2N5@1117|Cyanobacteria,1H741@1150|Oscillatoriales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
YYD3_k127_6527520_5	56110.Oscil6304_4194	8.367e-92	311.0	COG1352@1|root,COG1352@2|Bacteria,1G4QS@1117|Cyanobacteria,1H8YH@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575,ko:K13486	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
YYD3_k127_6527520_1	1173028.ANKO01000214_gene6277	3.636e-219	712.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YYD3_k127_6527520_7	1173028.ANKO01000214_gene6278	2.657e-76	268.0	COG0840@1|root,COG0840@2|Bacteria,1G4MY@1117|Cyanobacteria,1HA77@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
YYD3_k127_6560232_1	715451.ambt_12010	1.721e-08	65.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6560232_2	237368.SCABRO_03991	0.0003042	51.0	COG0515@1|root,COG1470@1|root,COG1572@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM9_1,DUF4114,PEGA,PPC,SASA
YYD3_k127_6560232_0	1142394.PSMK_23140	5.965e-53	192.0	COG1225@1|root,COG1225@2|Bacteria,2IZIQ@203682|Planctomycetes	203682|Planctomycetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD3_k127_6568774_9	1267533.KB906734_gene3716	0.0001525	47.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria,2JHXV@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
YYD3_k127_6568774_1	404589.Anae109_2766	1.389e-115	383.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
YYD3_k127_6568774_3	1209072.ALBT01000032_gene2122	1.008e-31	141.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_6568774_2	1047013.AQSP01000071_gene1930	1.481e-114	383.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
YYD3_k127_6568774_7	167539.Pro_1333	2.62e-13	79.0	COG2242@1|root,COG2242@2|Bacteria,1GAGS@1117|Cyanobacteria	1117|Cyanobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YYD3_k127_6568774_4	65093.PCC7418_1862	1.098e-29	130.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD3_k127_6568774_0	504472.Slin_4367	1.057e-130	436.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes	976|Bacteroidetes	E	(GMC) oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
YYD3_k127_6568774_5	290399.Arth_0931	9.039e-24	106.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
YYD3_k127_6568774_6	661478.OP10G_2268	3.914e-16	83.0	2END1@1|root,33G0I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6568774_10	398527.Bphyt_7273	0.0001622	48.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,1K4RQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YYD3_k127_6568774_8	438753.AZC_0688	6.884e-06	49.0	COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria,2TVEH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YYD3_k127_6573501_15	234267.Acid_0699	1.14e-19	93.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_6573501_18	1408418.JNJH01000005_gene2016	0.0009548	51.0	COG2227@1|root,COG2227@2|Bacteria,1MZYD@1224|Proteobacteria,2UG70@28211|Alphaproteobacteria,2JWZW@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_6573501_2	1246995.AFR_03485	1.275e-116	401.0	2EZGX@1|root,2ZBAK@2|Bacteria,2IEK8@201174|Actinobacteria,4DI24@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6573501_10	1267535.KB906767_gene743	2.455e-41	156.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
YYD3_k127_6573501_13	234267.Acid_7092	1.447e-23	103.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria	57723|Acidobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
YYD3_k127_6573501_14	1340493.JNIF01000004_gene998	1.33e-21	100.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria	57723|Acidobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
YYD3_k127_6573501_9	1385513.N780_09750	1.826e-50	186.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,2Y97J@289201|Pontibacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
YYD3_k127_6573501_7	204669.Acid345_4539	8.66e-52	196.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
YYD3_k127_6573501_1	1267535.KB906767_gene748	4.063e-118	402.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria,2JHTF@204432|Acidobacteriia	204432|Acidobacteriia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
YYD3_k127_6573501_6	1121422.AUMW01000011_gene150	1.407e-52	199.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,261HE@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD3_k127_6573501_3	69395.JQLZ01000003_gene37	1.962e-87	300.0	COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,2U5FS@28211|Alphaproteobacteria,2KHTF@204458|Caulobacterales	204458|Caulobacterales	M	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
YYD3_k127_6573501_11	671143.DAMO_0503	7.036e-31	138.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NPEN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	ko:K11935	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	TPR_1,TPR_15,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
YYD3_k127_6573501_16	1047013.AQSP01000138_gene1048	8.648e-18	84.0	COG2835@1|root,COG2835@2|Bacteria,2NQ60@2323|unclassified Bacteria	2|Bacteria	S	Trm112p-like protein	ycaR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.1.130	ko:K00912,ko:K09791	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Trm112p
YYD3_k127_6573501_8	1047013.AQSP01000138_gene1047	1.747e-50	192.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD3_k127_6573501_5	1047013.AQSP01000138_gene1046	1.816e-54	207.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
YYD3_k127_6573501_4	330214.NIDE2553	6.531e-63	228.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
YYD3_k127_6573501_0	1267534.KB906756_gene278	9.561e-152	496.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
YYD3_k127_6573501_12	671143.DAMO_0140	2.969e-28	117.0	COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria	2|Bacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
YYD3_k127_6592169_1	1288494.EBAPG3_16480	1.88e-43	163.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,2VIIT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	type VI secretion protein	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
YYD3_k127_6592169_0	1157708.KB907455_gene3461	0.0	1295.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,4AAVS@80864|Comamonadaceae	28216|Betaproteobacteria	O	TIGRFAM type VI secretion ATPase, ClpV1 family	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD3_k127_6592169_2	765913.ThidrDRAFT_2830	6.045e-29	121.0	COG0457@1|root,COG4976@1|root,COG0457@2|Bacteria,COG4976@2|Bacteria,1RAIT@1224|Proteobacteria,1S6MW@1236|Gammaproteobacteria,1X01X@135613|Chromatiales	135613|Chromatiales	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
YYD3_k127_65999_0	1340493.JNIF01000003_gene3965	5.245e-118	394.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_65999_1	1047013.AQSP01000088_gene1631	4.276e-27	130.0	COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria	2|Bacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_6613633_9	179408.Osc7112_0935	1.183e-31	131.0	2DMJE@1|root,32RYR@2|Bacteria,1G6SI@1117|Cyanobacteria,1HBXF@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
YYD3_k127_6613633_4	290397.Adeh_3929	4.647e-122	398.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YYD3_k127_6613633_11	754477.Q7C_791	4.843e-10	72.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales	72273|Thiotrichales	M	PFAM AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
YYD3_k127_6613633_10	331113.SNE_A11730	8.479e-16	84.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
YYD3_k127_6613633_2	469381.Dpep_0227	2.487e-132	430.0	COG0451@1|root,COG0451@2|Bacteria,3TAV7@508458|Synergistetes	508458|Synergistetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD3_k127_6613633_0	234267.Acid_0283	3.858e-155	497.0	COG0399@1|root,COG0399@2|Bacteria,3Y3PT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_6613633_3	926566.Terro_0959	7.469e-128	432.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YYD3_k127_6613633_1	398767.Glov_2173	2.65e-139	456.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YYD3_k127_6613633_6	1430440.MGMSRv2_3470	2.776e-56	211.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VF0J@28211|Alphaproteobacteria,2JYN6@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YYD3_k127_6613633_7	234267.Acid_0956	1.921e-54	198.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YYD3_k127_6613633_8	1125863.JAFN01000001_gene99	4.257e-45	173.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
YYD3_k127_6613633_5	1499967.BAYZ01000068_gene1977	1.891e-93	313.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
YYD3_k127_6615483_6	1121918.ARWE01000001_gene3313	1.432e-89	304.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_6615483_9	1125863.JAFN01000001_gene2827	2.292e-54	208.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
YYD3_k127_6615483_3	398767.Glov_3628	6.912e-190	616.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YYD3_k127_6615483_10	767817.Desgi_1265	1.429e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_6615483_5	452637.Oter_3914	1.564e-91	317.0	COG0531@1|root,COG0531@2|Bacteria,46SPF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
YYD3_k127_6615483_13	262724.TT_C1407	1.587e-05	57.0	COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
YYD3_k127_6615483_8	204669.Acid345_0214	5.475e-73	252.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
YYD3_k127_6615483_2	204669.Acid345_0212	7.4e-192	608.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
YYD3_k127_6615483_1	1242864.D187_004920	1.919e-220	698.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
YYD3_k127_6615483_12	526225.Gobs_1101	3.895e-11	76.0	COG4733@1|root,COG4733@2|Bacteria,2HH13@201174|Actinobacteria,4EW6W@85013|Frankiales	201174|Actinobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
YYD3_k127_6615483_7	1191523.MROS_1726	5.548e-88	295.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YYD3_k127_6615483_0	1382359.JIAL01000001_gene1070	7.969e-245	765.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD3_k127_6615483_4	234267.Acid_1858	3.888e-152	498.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria	57723|Acidobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD3_k127_6615483_11	290397.Adeh_0258	4.02e-21	101.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2Z2BY@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YYD3_k127_6615483_14	267608.RSc0896	1.885e-05	53.0	COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,1K3FN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
YYD3_k127_6616868_2	1459636.NTE_02870	3.726e-27	113.0	COG5588@1|root,arCOG11393@2157|Archaea	1459636.NTE_02870|-	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6616868_1	234267.Acid_7677	1.494e-49	183.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_6616868_0	204669.Acid345_1052	2.56e-110	391.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YYD3_k127_6618781_2	1236959.BAMT01000015_gene2850	2.275e-22	107.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6618781_0	1379270.AUXF01000001_gene1899	1.719e-89	314.0	COG0251@1|root,COG3391@1|root,COG0251@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP,VCBS
YYD3_k127_6618781_1	479435.Kfla_4818	2e-39	155.0	COG1011@1|root,COG1011@2|Bacteria,2ISM0@201174|Actinobacteria,4DSGW@85009|Propionibacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
YYD3_k127_6635013_1	358220.C380_05850	4.405e-76	262.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,2VI3X@28216|Betaproteobacteria,4AGHI@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_6635013_0	1158292.JPOE01000002_gene1994	5.086e-89	300.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VP0A@28216|Betaproteobacteria,1KPHE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_6635013_2	266117.Rxyl_2941	2.802e-74	257.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
YYD3_k127_6635013_5	1123368.AUIS01000001_gene1907	0.0001125	48.0	COG5002@1|root,COG5002@2|Bacteria,1QVXJ@1224|Proteobacteria,1T2NA@1236|Gammaproteobacteria,2NE6W@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
YYD3_k127_6635013_4	378806.STAUR_2790	1.129e-05	53.0	2EFSR@1|root,339IR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
YYD3_k127_6635013_3	518766.Rmar_2227	7.592e-55	201.0	COG2197@1|root,COG2197@2|Bacteria,4NP2G@976|Bacteroidetes,1FIR1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_6652803_3	1267535.KB906767_gene3868	2.357e-199	653.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_6652803_1	1123389.ATXJ01000003_gene325	1.145e-231	728.0	COG4147@1|root,COG4147@2|Bacteria,1WIVG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
YYD3_k127_6652803_20	1297742.A176_05405	1.523e-22	100.0	COG3162@1|root,COG3162@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
YYD3_k127_6652803_16	247633.GP2143_17801	9.954e-42	158.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6652803_11	247633.GP2143_17791	1.294e-76	267.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6652803_9	76869.PputGB1_3090	5.375e-98	332.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1YWV4@136845|Pseudomonas putida group	1236|Gammaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_2698	Meth_synt_2
YYD3_k127_6652803_6	1163617.SCD_n01504	6.116e-120	403.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_6652803_0	1382306.JNIM01000001_gene2330	3.141e-303	946.0	COG0365@1|root,COG0365@2|Bacteria,2G83G@200795|Chloroflexi	200795|Chloroflexi	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD3_k127_6652803_14	671143.DAMO_1432	4.417e-54	196.0	COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria	2|Bacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_6652803_12	225937.HP15_2739	8.683e-69	239.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,1S5J1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD3_k127_6652803_15	247633.GP2143_17796	2.964e-43	171.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6652803_5	627192.SLG_04410	7.844e-183	594.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K1V6@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_6652803_4	1267535.KB906767_gene2430	5.116e-191	618.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_6652803_19	247633.GP2143_13056	8.697e-25	117.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6652803_2	234267.Acid_0926	2.881e-229	721.0	COG1473@1|root,COG1473@2|Bacteria	2|Bacteria	S	N-acetyldiaminopimelate deacetylase activity	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_6652803_17	1038858.AXBA01000067_gene1365	5.534e-35	147.0	COG0725@1|root,COG0725@2|Bacteria,1RCHM@1224|Proteobacteria,2VGBX@28211|Alphaproteobacteria,3F2CK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	5.3.3.7	ko:K02020,ko:K22003	ko00660,ko02010,map00660,map02010	M00189	R02244	RC00668	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	SBP_bac_11
YYD3_k127_6652803_7	1340493.JNIF01000003_gene3965	1.714e-112	379.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_6652803_22	2002.JOEQ01000075_gene4075	0.0003671	48.0	COG3469@1|root,COG4733@1|root,COG3469@2|Bacteria,COG4733@2|Bacteria,2GJH0@201174|Actinobacteria,4EHCT@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 18	chiB	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,CBM_4_9,Glyco_hydro_18,fn3
YYD3_k127_6652803_10	1150864.MILUP08_42081	1.581e-86	295.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
YYD3_k127_6652803_8	234267.Acid_4038	1.658e-104	347.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
YYD3_k127_6652803_18	234267.Acid_4039	3.135e-27	121.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YYD3_k127_6652803_13	1340493.JNIF01000003_gene3608	1.621e-66	244.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
YYD3_k127_6652803_21	671143.DAMO_1104	2.048e-19	93.0	COG3746@1|root,COG3746@2|Bacteria,2NRQ1@2323|unclassified Bacteria	2|Bacteria	P	phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
YYD3_k127_6661498_15	622637.KE124774_gene1562	1.15e-39	161.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD3_k127_6661498_11	861299.J421_1254	3.41e-43	162.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_6661498_3	1267533.KB906733_gene2863	2.432e-98	344.0	COG2984@1|root,COG4585@1|root,COG2984@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_3,PAS_9
YYD3_k127_6661498_5	1007104.SUS17_2461	5.013e-82	289.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_6661498_17	1379270.AUXF01000004_gene2925	2.866e-32	132.0	COG1846@1|root,COG1846@2|Bacteria,1ZU3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
YYD3_k127_6661498_12	234267.Acid_6292	1.139e-42	163.0	COG3127@1|root,COG3127@2|Bacteria,3Y7ZT@57723|Acidobacteria	57723|Acidobacteria	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6661498_14	1210884.HG799469_gene14239	2.274e-41	156.0	COG2947@1|root,COG2947@2|Bacteria,2IZM3@203682|Planctomycetes	203682|Planctomycetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
YYD3_k127_6661498_18	1379270.AUXF01000001_gene2650	4.925e-21	104.0	COG4591@1|root,COG4591@2|Bacteria	1379270.AUXF01000001_gene2650|-	M	lipoprotein localization to outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6661498_13	861299.J421_4357	1.031e-41	173.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_6661498_7	861299.J421_4356	1.552e-76	262.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_6661498_16	861299.J421_4355	2.262e-39	168.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6661498_19	66373.JOFQ01000006_gene3002	2.266e-11	77.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6661498_6	76114.p2A138	2.306e-77	263.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
YYD3_k127_6661498_9	1128427.KB904821_gene174	1.576e-63	228.0	COG0705@1|root,COG0705@2|Bacteria,1G5IY@1117|Cyanobacteria,1HF1W@1150|Oscillatoriales	1117|Cyanobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD3_k127_6661498_4	926569.ANT_03360	5.068e-86	292.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
YYD3_k127_6661498_0	1038860.AXAP01000018_gene3108	6.357e-198	634.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_6661498_2	1173027.Mic7113_2540	1.155e-99	332.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
YYD3_k127_6661498_8	1095769.CAHF01000006_gene1870	1.061e-75	271.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2VKPI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
YYD3_k127_6661498_10	1340493.JNIF01000003_gene4244	2.717e-51	188.0	2ANK7@1|root,31DJB@2|Bacteria,3Y7J7@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
YYD3_k127_6661498_1	234267.Acid_7172	1.338e-113	398.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y7WS@57723|Acidobacteria	57723|Acidobacteria	T	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_6665034_2	697281.Mahau_1416	7.677e-66	239.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,42FQD@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Class II aldolase adducin	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YYD3_k127_6665034_4	485915.Dret_1349	6.551e-05	49.0	COG3350@1|root,COG3350@2|Bacteria,1NCWJ@1224|Proteobacteria,42WJP@68525|delta/epsilon subdivisions,2WS92@28221|Deltaproteobacteria,2MD2M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART TRASH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
YYD3_k127_6665034_3	1121918.ARWE01000001_gene1089	8.826e-18	91.0	COG0457@1|root,COG0457@2|Bacteria,1PHH0@1224|Proteobacteria,42TAV@68525|delta/epsilon subdivisions,2X2DM@28221|Deltaproteobacteria,43UTK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YYD3_k127_6665034_1	391625.PPSIR1_11450	5.696e-84	285.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
YYD3_k127_6665034_0	338963.Pcar_1001	1.201e-106	357.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,43T4H@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD3_k127_6682516_3	98439.AJLL01000090_gene71	7.098e-13	74.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_6682516_1	756272.Plabr_4336	1.611e-36	150.0	COG0614@1|root,COG0614@2|Bacteria,2J06G@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YYD3_k127_6682516_5	1386089.N865_01135	0.0004643	49.0	COG0265@1|root,COG0265@2|Bacteria,2ICC4@201174|Actinobacteria,4FI5B@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6682516_4	446462.Amir_6760	0.0002458	47.0	COG0265@1|root,COG0265@2|Bacteria,2ICC4@201174|Actinobacteria,4E1VC@85010|Pseudonocardiales	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6682516_0	1519464.HY22_04445	3.803e-250	790.0	COG1770@1|root,COG1770@2|Bacteria,1FDQZ@1090|Chlorobi	1090|Chlorobi	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.21.26,3.4.21.83	ko:K01322,ko:K01354	ko04614,ko05142,ko05143,map04614,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
YYD3_k127_6682516_2	522306.CAP2UW1_1835	1.722e-36	139.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2VKYS@28216|Betaproteobacteria,1KR3R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Inorganic ion transport and metabolism	ybhI	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
YYD3_k127_6690058_18	335543.Sfum_1616	2.116e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1PFBA@1224|Proteobacteria,43755@68525|delta/epsilon subdivisions,2WQN6@28221|Deltaproteobacteria,2MSBR@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
YYD3_k127_6690058_2	335543.Sfum_1617	2.526e-173	560.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_6690058_12	449447.MAE_49220	8.728e-16	84.0	COG1595@1|root,COG1595@2|Bacteria,1G5PA@1117|Cyanobacteria	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD3_k127_6690058_9	383372.Rcas_4353	7.598e-21	108.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YYD3_k127_6690058_6	395965.Msil_2521	1.519e-104	355.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_6690058_0	1380394.JADL01000001_gene2380	5.034e-226	715.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2JR1Q@204441|Rhodospirillales	204441|Rhodospirillales	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
YYD3_k127_6690058_7	1304878.AUGD01000006_gene6536	2.847e-83	284.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,3JVGF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
YYD3_k127_6690058_14	231434.JQJH01000001_gene1857	2.505e-12	74.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,1RG3J@1224|Proteobacteria,2U7QD@28211|Alphaproteobacteria,3NBV8@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_6690058_5	331113.SNE_A16720	2.511e-106	358.0	COG1071@1|root,COG1071@2|Bacteria,2JFFX@204428|Chlamydiae	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
YYD3_k127_6690058_3	1131269.AQVV01000006_gene429	8.19e-145	467.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YYD3_k127_6690058_1	1123487.KB892839_gene126	8.336e-176	567.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VHA9@28216|Betaproteobacteria,2KVY5@206389|Rhodocyclales	206389|Rhodocyclales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_6690058_4	156889.Mmc1_0618	7.88e-137	441.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TT56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD3_k127_6690058_15	1396141.BATP01000035_gene4051	2.257e-11	79.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
YYD3_k127_6690058_8	1210884.HG799466_gene12414	5.614e-65	256.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox,DUF616,Glycos_transf_2,TPR_8
YYD3_k127_6690058_17	83219.PM02_06450	7.25e-09	70.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,3ZVZM@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
YYD3_k127_6690058_10	1121448.DGI_0140	2.97e-19	105.0	COG0500@1|root,COG2226@2|Bacteria,1QYS8@1224|Proteobacteria,43DF8@68525|delta/epsilon subdivisions,2X8M7@28221|Deltaproteobacteria,2ME6A@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6690058_19	234267.Acid_0655	0.0002612	52.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_32,NodS
YYD3_k127_6690058_11	467200.ACFA01000913_gene3389	6.313e-19	96.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
YYD3_k127_6690058_13	203119.Cthe_2456	2.566e-14	80.0	arCOG06471@1|root,32BPX@2|Bacteria,1VD13@1239|Firmicutes,24M2I@186801|Clostridia	186801|Clostridia	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
YYD3_k127_6690058_16	572546.Arcpr_0656	3.791e-10	72.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,245XG@183980|Archaeoglobi	183980|Archaeoglobi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_6695062_0	234267.Acid_3680	1.452e-155	514.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6702015_4	861299.J421_6223	5.658e-86	306.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6702015_6	521045.Kole_0405	1.377e-08	61.0	COG1063@1|root,COG1063@2|Bacteria,2GCH6@200918|Thermotogae	200918|Thermotogae	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
YYD3_k127_6702015_0	234267.Acid_5940	1.245e-166	556.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_6702015_3	756272.Plabr_3552	7.159e-102	341.0	COG1063@1|root,COG1063@2|Bacteria,2IZ2T@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
YYD3_k127_6702015_5	7668.SPU_022553-tr	1.844e-34	152.0	COG0666@1|root,KOG1480@1|root,KOG1480@2759|Eukaryota,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	1.14.13.225	ko:K07521,ko:K15502,ko:K19947	ko04360,map04360	-	-	-	ko00000,ko00001,ko01000,ko01009,ko03400,ko04131,ko04516	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,Death,ZU5
YYD3_k127_6702015_2	886293.Sinac_1154	1.055e-125	419.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_6702015_1	234267.Acid_5827	1.321e-166	537.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_6707627_0	485915.Dret_0311	7.251e-254	812.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2M7ZN@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD3_k127_6707627_1	379066.GAU_3242	5.684e-84	291.0	COG0666@1|root,COG0666@2|Bacteria,1ZV8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4
YYD3_k127_6707627_2	861299.J421_1875	2.499e-22	102.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
YYD3_k127_6707627_3	1379270.AUXF01000002_gene1318	2.711e-15	80.0	2E363@1|root,32Y5Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6707627_4	1089547.KB913013_gene761	1e-10	67.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YYD3_k127_6722565_0	1242864.D187_000308	5.731e-169	547.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
YYD3_k127_6722714_0	204669.Acid345_3936	1.345e-178	569.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_6722714_1	269799.Gmet_1196	1.863e-15	82.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,42XQG@68525|delta/epsilon subdivisions,2WT9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
YYD3_k127_6744086_1	1121434.AULY01000009_gene2038	2.592e-13	82.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YYD3_k127_6744086_0	1340493.JNIF01000003_gene3295	5.874e-52	190.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
YYD3_k127_6788756_0	382464.ABSI01000006_gene852	2.918e-213	669.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	preT	-	1.2.7.1	ko:K00171,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_6,PFOR_II,POR,POR_N,Pyr_redox_2,Pyr_redox_3,TPP_enzyme_C
YYD3_k127_6788756_1	340177.Cag_1756	5.152e-29	123.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
YYD3_k127_6796179_9	880072.Desac_1766	4.335e-52	202.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2MRHP@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
YYD3_k127_6796179_10	1517416.IDAT_06985	2.782e-48	195.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,2QFKA@267893|Idiomarinaceae	1236|Gammaproteobacteria	U	General secretion pathway	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1,T2SSB
YYD3_k127_6796179_18	1173029.JH980292_gene3658	0.0002575	49.0	2DR31@1|root,339YG@2|Bacteria,1GAVI@1117|Cyanobacteria,1HDY2@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
YYD3_k127_6796179_13	886293.Sinac_3291	3.655e-37	146.0	COG4636@1|root,COG4636@2|Bacteria,2J0XX@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_6796179_5	1078020.KEK_03887	5.987e-114	386.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,235ZB@1762|Mycobacteriaceae	201174|Actinobacteria	K	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
YYD3_k127_6796179_14	1089551.KE386572_gene1280	1.584e-34	143.0	COG2520@1|root,COG2520@2|Bacteria,1MZTC@1224|Proteobacteria,2UE8C@28211|Alphaproteobacteria,4BSBW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YYD3_k127_6796179_4	1267535.KB906767_gene3834	3.667e-118	413.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6796179_12	240015.ACP_2126	5.601e-43	160.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_6796179_7	243090.RB8505	1.134e-87	306.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_6796179_6	1347369.CCAD010000086_gene1738	1.708e-93	316.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus	91061|Bacilli	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YYD3_k127_6796179_8	1298858.AUEL01000019_gene3259	1.293e-58	211.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VFHH@28211|Alphaproteobacteria,43RJV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YYD3_k127_6796179_11	251221.35214559	2.373e-45	182.0	COG2202@1|root,COG2203@1|root,COG3290@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG4585@2|Bacteria,1G041@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_4
YYD3_k127_6796179_3	1109445.AGSX01000010_gene1489	1.387e-119	395.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1Z0V1@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mexE	-	-	ko:K18298	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD3_k127_6796179_0	666685.R2APBS1_0072	0.0	1441.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales	135614|Xanthomonadales	V	Efflux pump membrane transporter	-	-	-	ko:K18299	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.16	-	-	ACR_tran
YYD3_k127_6796179_2	401053.AciPR4_1207	6.059e-131	432.0	COG1538@1|root,COG1538@2|Bacteria,3Y4ES@57723|Acidobacteria,2JJ4B@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18300	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17	-	-	OEP
YYD3_k127_6796179_1	234267.Acid_5810	4.294e-161	514.0	COG3214@1|root,COG3214@2|Bacteria,3Y96S@57723|Acidobacteria	57723|Acidobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
YYD3_k127_6796179_17	643867.Ftrac_3797	0.0002392	47.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6844041_1	234267.Acid_5749	7.345e-100	351.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6844041_0	266779.Meso_2605	6.766e-174	553.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	MA20_34345	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_68485_0	197221.22294486	8.588e-299	929.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	Intein_splicing,PEP-utilizers,PEP-utilizers_C,PPDK_N
YYD3_k127_6868939_3	926550.CLDAP_05380	1.013e-10	69.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_6868939_4	1036674.A28LD_0930	3.674e-05	54.0	COG2133@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,1R269@1224|Proteobacteria,1S1GT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
YYD3_k127_6868939_1	572544.Ilyop_0968	3.269e-16	88.0	COG1622@1|root,COG1622@2|Bacteria,37CJY@32066|Fusobacteria	2|Bacteria	C	cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
YYD3_k127_6868939_0	477641.MODMU_1166	2.442e-41	160.0	COG1813@1|root,COG3903@1|root,COG1813@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUW7@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,Trans_reg_C
YYD3_k127_690697_0	234267.Acid_5856	2.256e-172	570.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_690697_2	215803.DB30_5720	2.592e-09	67.0	COG0784@1|root,COG1716@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1716@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2Z2WB@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
YYD3_k127_690697_1	1267535.KB906767_gene4240	2.087e-12	77.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
YYD3_k127_690697_3	479431.Namu_2474	4.346e-05	52.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2GNXG@201174|Actinobacteria,4EUTH@85013|Frankiales	201174|Actinobacteria	KLT	Lactonase, 7-bladed beta-propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Lactonase,Pkinase
YYD3_k127_697082_20	234267.Acid_7647	2.539e-35	141.0	COG1629@1|root,COG1629@2|Bacteria,3Y721@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
YYD3_k127_697082_5	251229.Chro_1581	9.153e-103	351.0	COG1914@1|root,COG1914@2|Bacteria,1GIFV@1117|Cyanobacteria,3VM6A@52604|Pleurocapsales	1117|Cyanobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697082_22	247490.KSU1_D0807	6.764e-23	111.0	2BRMQ@1|root,32KM4@2|Bacteria,2J4AR@203682|Planctomycetes	247490.KSU1_D0807|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697082_4	697282.Mettu_2234	3.872e-105	359.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_697082_14	269482.Bcep1808_5588	3.157e-40	161.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,2VZGG@28216|Betaproteobacteria,1KGYH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697082_0	234267.Acid_5783	4.404e-273	855.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_697082_1	543728.Vapar_0124	7.726e-198	631.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VIK2@28216|Betaproteobacteria,4ACVQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_697082_7	1380355.JNIJ01000089_gene2468	2.419e-98	345.0	COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2V8VX@28211|Alphaproteobacteria,3K1ZD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697082_19	68170.KL590577_gene8231	1.635e-37	161.0	COG3250@1|root,COG3345@1|root,COG3250@2|Bacteria,COG3345@2|Bacteria,2GKJ5@201174|Actinobacteria,4DZRH@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,NPCBM,NPCBM_assoc
YYD3_k127_697082_11	1134912.AJTV01000010_gene651	9.81e-43	167.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_697082_10	1540221.JQNI01000004_gene233	1.325e-70	274.0	COG0429@1|root,COG3055@1|root,COG0429@2|Bacteria,COG3055@2|Bacteria,1WKZU@1297|Deinococcus-Thermus	2|Bacteria	S	NPCBM	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,NPCBM
YYD3_k127_697082_13	1121377.KB906440_gene3652	3.112e-41	177.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.1.3.1	ko:K01113,ko:K13735,ko:K20276	ko00790,ko01100,ko02020,ko02024,ko05100,map00790,map01100,map02020,map02024,map05100	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ASH,DUF4347
YYD3_k127_697082_2	1242864.D187_009349	1.287e-137	488.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1R86D@1224|Proteobacteria	1224|Proteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,GSDH
YYD3_k127_697082_23	469383.Cwoe_5232	3.768e-06	55.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQVE@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	SNase,YdjM
YYD3_k127_697082_18	1123322.KB904636_gene2696	1.239e-37	162.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	DUF4968,DUF5110,F5_F8_type_C,GH97_C,GH97_N,Glyco_hydro_31,Glyco_hydro_97,Melibiase_2,NPCBM,NPCBM_assoc
YYD3_k127_697082_9	118173.KB235914_gene1474	3.848e-72	269.0	COG2911@1|root,COG2931@1|root,COG3391@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G2NP@1117|Cyanobacteria,1H73B@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,HemolysinCabind
YYD3_k127_697082_21	1463879.JOHP01000001_gene1422	3.686e-35	154.0	COG1082@1|root,COG1874@1|root,COG1082@2|Bacteria,COG1874@2|Bacteria,2GKFD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase 97	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,NPCBM,NPCBM_assoc,RicinB_lectin_2
YYD3_k127_697082_16	219305.MCAG_05515	6.345e-39	167.0	COG1470@1|root,COG3250@1|root,COG1470@2|Bacteria,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4D8FK@85008|Micromonosporales	201174|Actinobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM,NPCBM_assoc
YYD3_k127_697082_8	1463887.KL589982_gene4660	5.19e-79	290.0	COG1572@1|root,COG2706@1|root,COG1572@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8,VCBS,fn3
YYD3_k127_697082_15	319795.Dgeo_2665	2.697e-39	168.0	COG0429@1|root,COG3055@1|root,COG0429@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,NPCBM
YYD3_k127_697082_3	555079.Toce_0508	5.023e-113	378.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_697082_6	56110.Oscil6304_2653	1.007e-100	357.0	COG0438@1|root,COG0438@2|Bacteria,1G8JK@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
YYD3_k127_697082_17	479434.Sthe_3448	8.939e-38	158.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YYD3_k127_697082_12	373994.Riv7116_0476	9.887e-43	169.0	COG1215@1|root,COG1215@2|Bacteria,1GPZX@1117|Cyanobacteria,1HTUS@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_697439_3	309801.trd_1606	1.94e-57	211.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_697439_1	278963.ATWD01000002_gene495	7.83e-78	264.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
YYD3_k127_697439_5	247633.GP2143_17796	1.01e-50	194.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697439_7	1410618.JNKI01000001_gene1256	1.013e-16	95.0	COG1629@1|root,COG4771@2|Bacteria,1TQBP@1239|Firmicutes,4H2P2@909932|Negativicutes	909932|Negativicutes	P	TonB-dependent receptor	cirA	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
YYD3_k127_697439_9	251221.35211983	6.013e-06	48.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_697439_2	1163409.UUA_11808	2.116e-67	241.0	COG0454@1|root,COG0456@2|Bacteria,1NDD2@1224|Proteobacteria	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_697439_0	234267.Acid_2340	3.636e-105	351.0	COG0463@1|root,COG0463@2|Bacteria,3Y6XH@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
YYD3_k127_697439_6	379066.GAU_0953	6.776e-32	130.0	2BBQ7@1|root,3258A@2|Bacteria,1ZUVG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697439_4	1128421.JAGA01000003_gene3009	3.27e-57	212.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,SGL,VCBS
YYD3_k127_697439_10	1123020.AUIE01000010_gene1150	5.057e-05	48.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_697439_11	926566.Terro_0943	5.438e-05	54.0	COG1629@1|root,COG4771@2|Bacteria	926566.Terro_0943|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_697439_8	290315.Clim_0460	2.268e-11	68.0	COG4704@1|root,COG4704@2|Bacteria,1FEFF@1090|Chlorobi	1090|Chlorobi	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
YYD3_k127_734503_7	1267535.KB906767_gene2430	2.823e-11	68.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_734503_2	204669.Acid345_2395	4.295e-84	307.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
YYD3_k127_734503_3	234267.Acid_3247	5.337e-41	159.0	294EW@1|root,2ZRUR@2|Bacteria,3Y5CG@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
YYD3_k127_734503_1	1267535.KB906767_gene5147	2.289e-178	572.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YYD3_k127_734503_0	234267.Acid_7551	6.434e-189	620.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_734503_4	1430331.EP10_06065	1.037e-33	147.0	COG1807@1|root,COG1807@2|Bacteria,1UY16@1239|Firmicutes,4HF2X@91061|Bacilli,1WG5K@129337|Geobacillus	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD3_k127_734503_5	234267.Acid_2539	5.742e-32	136.0	2DJMQ@1|root,32UDD@2|Bacteria,3Y57W@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_734503_6	234267.Acid_2537	4.475e-14	73.0	COG1595@1|root,COG1595@2|Bacteria,3Y5RY@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_739268_2	101510.RHA1_ro02599	6.091e-83	278.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4FUVW@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
YYD3_k127_739268_1	1121875.KB907547_gene3379	1.709e-97	334.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1HZVC@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
YYD3_k127_739268_3	582899.Hden_2289	4.955e-50	188.0	COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,2TUS4@28211|Alphaproteobacteria,3N7RX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
YYD3_k127_739268_0	420324.KI911999_gene8064	3.668e-203	644.0	28JZZ@1|root,2Z9PZ@2|Bacteria,1N3C6@1224|Proteobacteria,2TSCX@28211|Alphaproteobacteria,1JTZB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_743396_0	861299.J421_0887	4.656e-125	422.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1ZUNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_812169_4	344747.PM8797T_21603	4.552e-47	178.0	COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_812169_1	1121434.AULY01000012_gene2853	1.241e-92	331.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WMEW@28221|Deltaproteobacteria,2M8IE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_812169_0	344747.PM8797T_00512	2.561e-114	382.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_812169_3	1210884.HG799465_gene12146	8.085e-83	289.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_812169_7	234267.Acid_1304	1.781e-05	51.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_812169_6	330214.NIDE0632	5.828e-28	128.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
YYD3_k127_812169_2	903818.KI912268_gene2429	5.315e-85	293.0	COG0231@1|root,COG0231@2|Bacteria,3Y2GH@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YYD3_k127_812169_5	234267.Acid_6900	1.683e-31	136.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
YYD3_k127_820085_0	420324.KI911999_gene8064	4.601e-200	627.0	28JZZ@1|root,2Z9PZ@2|Bacteria,1N3C6@1224|Proteobacteria,2TSCX@28211|Alphaproteobacteria,1JTZB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_820085_3	1160137.KB907307_gene601	2.876e-48	190.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4G061@85025|Nocardiaceae	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_820085_4	247633.GP2143_18126	1.951e-33	143.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_820085_5	1209984.BN978_06070	2.481e-18	93.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
YYD3_k127_820085_2	234267.Acid_7518	2.598e-57	211.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	hrpQ	-	4.6.1.1	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	M00332,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	3.A.6.1	-	-	FHA,Yop-YscD_cpl,Yop-YscD_ppl,cNMP_binding
YYD3_k127_820085_1	234267.Acid_7519	1.956e-90	314.0	COG0631@1|root,COG0631@2|Bacteria,3Y4SV@57723|Acidobacteria	57723|Acidobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YYD3_k127_820085_6	215803.DB30_2329	3.745e-05	46.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1NR2V@1224|Proteobacteria,42YIK@68525|delta/epsilon subdivisions,2WUNG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MV	MacB-like periplasmic core domain	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_822320_3	1183438.GKIL_4363	9.669e-99	352.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_822320_11	1449976.KALB_6686	9.947e-09	58.0	COG3507@1|root,COG3507@2|Bacteria,2GNEY@201174|Actinobacteria,4DYJT@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43,RicinB_lectin_2
YYD3_k127_822320_7	246197.MXAN_3771	9.908e-34	141.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
YYD3_k127_822320_5	35720.XP_003648538.1	5.692e-72	254.0	2EBD3@1|root,2SHGJ@2759|Eukaryota,39TQZ@33154|Opisthokonta,3NZP0@4751|Fungi,3QR77@4890|Ascomycota,218S5@147550|Sordariomycetes,3UABU@5139|Sordariales,3HAHA@35718|Chaetomiaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_822320_4	1267535.KB906767_gene4357	2.066e-89	298.0	COG0782@1|root,COG0782@2|Bacteria,3Y351@57723|Acidobacteria,2JKIP@204432|Acidobacteriia	204432|Acidobacteriia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
YYD3_k127_822320_2	861299.J421_5759	3.018e-113	392.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_822320_1	767817.Desgi_2717	2.423e-181	582.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,26007@186807|Peptococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
YYD3_k127_822320_6	479434.Sthe_2283	5.543e-67	241.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_822320_9	1112212.JH584235_gene2729	2.15e-13	79.0	COG1278@1|root,COG1278@2|Bacteria,1QRMX@1224|Proteobacteria,2V17U@28211|Alphaproteobacteria,2KB7U@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock protein domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
YYD3_k127_822320_0	1267535.KB906767_gene1400	2.378e-285	900.0	COG0577@1|root,COG0577@2|Bacteria,3Y3V2@57723|Acidobacteria,2JM9M@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_822320_8	204669.Acid345_1110	9.096e-31	123.0	COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria,2JNG0@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
YYD3_k127_848771_1	671143.DAMO_1877	1.386e-93	331.0	COG5000@1|root,COG5000@2|Bacteria,2NQZA@2323|unclassified Bacteria	2|Bacteria	T	Multi-sensor signal transduction histidine kinase	ntrB	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
YYD3_k127_848771_0	671143.DAMO_1876	3.204e-163	526.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	nla6	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_848771_5	99598.Cal7507_4277	0.0002682	51.0	COG1266@1|root,COG1266@2|Bacteria,1G0ZJ@1117|Cyanobacteria,1HJ61@1161|Nostocales	1117|Cyanobacteria	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD3_k127_848771_3	1340493.JNIF01000003_gene1819	8.154e-46	192.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
YYD3_k127_848771_2	1382359.JIAL01000001_gene2312	1.195e-84	319.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
YYD3_k127_848771_4	1144275.COCOR_01071	2.356e-17	83.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2YVN7@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YYD3_k127_85632_6	247634.GPB2148_3282	7.7e-16	80.0	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,1J8Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
YYD3_k127_85632_3	1107311.Q767_03905	2.173e-26	117.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia,2NVED@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
YYD3_k127_85632_2	1278073.MYSTI_04273	1.389e-27	122.0	2E4EC@1|root,32Z9K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
YYD3_k127_85632_4	309807.SRU_0976	3.59e-18	98.0	COG0729@1|root,COG0729@2|Bacteria,4PF0B@976|Bacteroidetes,1FJXS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD3_k127_85632_0	1089550.ATTH01000001_gene1890	2.736e-68	256.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_85632_7	1136138.JH604627_gene22	2.589e-07	60.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
YYD3_k127_85632_1	1123242.JH636436_gene123	4.881e-47	181.0	COG0631@1|root,COG0631@2|Bacteria,2IZVG@203682|Planctomycetes	203682|Planctomycetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
YYD3_k127_85632_5	1333998.M2A_3056	1.096e-16	93.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,4BQKN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD3_k127_865439_0	1278073.MYSTI_02808	4.71e-127	415.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
YYD3_k127_865439_2	1459636.NTE_02056	0.0001725	52.0	COG2304@1|root,arCOG02902@2157|Archaea	2157|Archaea	O	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
YYD3_k127_865439_1	234267.Acid_7393	3.16e-24	108.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_880667_11	1379270.AUXF01000002_gene1145	1.122e-30	125.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_880667_10	136993.KB900627_gene392	7.437e-31	132.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_880667_0	234267.Acid_5827	2.937e-303	956.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_880667_2	886293.Sinac_1154	2.642e-187	601.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_880667_6	234267.Acid_5825	6.318e-143	470.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
YYD3_k127_880667_8	1267535.KB906767_gene5360	1.313e-74	260.0	COG3622@1|root,COG3622@2|Bacteria,3Y6XP@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YYD3_k127_880667_5	1123508.JH636450_gene7211	2.074e-163	550.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
YYD3_k127_880667_9	234267.Acid_6753	3.755e-63	234.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,3Y4DW@57723|Acidobacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1,3.4.21.53	ko:K01338,ko:K04757,ko:K06379,ko:K08282,ko:K17752	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01002,ko03021	-	-	-	HATPase_c_2,HTH_8,Response_reg
YYD3_k127_880667_12	1382359.JIAL01000001_gene2134	7.335e-20	93.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_880667_3	1340493.JNIF01000003_gene3440	2.135e-184	588.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,Laminin_G_3
YYD3_k127_880667_7	426355.Mrad2831_5916	3.218e-113	386.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,1JT6R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_880667_1	234267.Acid_6847	2.922e-213	695.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_880667_4	234267.Acid_3938	5.477e-165	551.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_880667_13	935840.JAEQ01000009_gene1380	0.0006651	43.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
YYD3_k127_891268_1	1123024.AUII01000038_gene4085	3.633e-100	344.0	COG1565@1|root,COG1565@2|Bacteria,2H31V@201174|Actinobacteria	201174|Actinobacteria	S	acr, cog1565	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YYD3_k127_891268_2	675635.Psed_2102	1.273e-96	327.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4DX7E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
YYD3_k127_891268_4	589865.DaAHT2_2428	5.538e-77	279.0	COG0685@1|root,COG0685@2|Bacteria,1NB3G@1224|Proteobacteria,42P1W@68525|delta/epsilon subdivisions,2WKDD@28221|Deltaproteobacteria,2MJ0X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
YYD3_k127_891268_0	1304880.JAGB01000002_gene2111	1.431e-186	598.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
YYD3_k127_891268_7	379066.GAU_3713	1.198e-30	127.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
YYD3_k127_891268_3	1267533.KB906734_gene3858	5.848e-92	313.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,MetW,Methyltransf_2
YYD3_k127_891268_9	1385517.N800_11085	1.467e-16	84.0	2BSVT@1|root,32MZC@2|Bacteria,1QCV9@1224|Proteobacteria,1T8NQ@1236|Gammaproteobacteria,1XAZU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_891268_8	1380386.JIAW01000005_gene1413	9.204e-26	116.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,239QW@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
YYD3_k127_891268_6	1121875.KB907547_gene3457	3.878e-36	140.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
YYD3_k127_891268_10	1499967.BAYZ01000095_gene4130	3.361e-14	77.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	pfs	-	3.2.2.1,3.2.2.9,4.1.99.14	ko:K01239,ko:K01243,ko:K03716	ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230	M00034,M00609	R00194,R01245,R01273,R01401,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YYD3_k127_891268_5	862908.BMS_0810	1.174e-37	148.0	COG3981@1|root,COG3981@2|Bacteria,1NC09@1224|Proteobacteria,43273@68525|delta/epsilon subdivisions,2WXQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YYD3_k127_908455_2	555793.WSK_2875	5.66e-07	54.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_908455_1	661478.OP10G_3689	1.338e-85	300.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_908455_0	1267535.KB906767_gene3591	6.849e-95	331.0	COG2333@1|root,COG2333@2|Bacteria,3Y323@57723|Acidobacteria,2JHP4@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_913365_2	1287276.X752_10820	0.0003633	50.0	COG2353@1|root,COG2885@1|root,COG2353@2|Bacteria,COG2885@2|Bacteria,1MZDI@1224|Proteobacteria,2U1GS@28211|Alphaproteobacteria,43HCE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,YceI
YYD3_k127_913365_0	317936.Nos7107_4889	3.037e-55	205.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria,1HNBR@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Ras
YYD3_k127_913365_1	32057.KB217478_gene2349	1.744e-14	81.0	COG0642@1|root,COG2205@2|Bacteria,1GBD6@1117|Cyanobacteria,1HJC9@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YYD3_k127_915625_4	1123070.KB899248_gene241	2.362e-119	399.0	COG1921@1|root,COG1921@2|Bacteria	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	selA	GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006	Se-cys_synth_N,SelA
YYD3_k127_915625_2	1123070.KB899259_gene1974	1.492e-130	439.0	COG3276@1|root,COG3276@2|Bacteria	2|Bacteria	J	selenocysteine insertion sequence binding	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
YYD3_k127_915625_6	1123242.JH636435_gene1453	3.031e-84	293.0	COG2218@1|root,COG2218@2|Bacteria,2IZIE@203682|Planctomycetes	203682|Planctomycetes	C	formylmethanofuran dehydrogenase subunit C	-	-	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
YYD3_k127_915625_0	1123242.JH636434_gene4170	1.168e-231	729.0	COG1229@1|root,COG1229@2|Bacteria,2IX6V@203682|Planctomycetes	203682|Planctomycetes	C	Formylmethanofuran dehydrogenase subunit A	-	-	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
YYD3_k127_915625_1	891968.Anamo_1144	4.008e-133	438.0	COG1029@1|root,COG1029@2|Bacteria,3TBWP@508458|Synergistetes	508458|Synergistetes	C	Molybdopterin oxidoreductase	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdopterin
YYD3_k127_915625_11	573064.Mefer_0156	4.355e-12	72.0	COG1153@1|root,arCOG02674@2157|Archaea,2XXYM@28890|Euryarchaeota,23QYY@183939|Methanococci	183939|Methanococci	C	PFAM molydopterin dinucleotide-binding region	fwdD	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114	1.2.7.12	ko:K00203	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Molydop_binding
YYD3_k127_915625_5	1380390.JIAT01000010_gene4327	3.714e-106	357.0	COG2037@1|root,COG2037@2|Bacteria	2|Bacteria	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
YYD3_k127_915625_3	234267.Acid_3047	4.671e-126	420.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YYD3_k127_915625_10	1101195.Meth11DRAFT_1464	7.176e-14	77.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_915625_9	136993.KB900627_gene392	1.509e-19	100.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_915625_7	1267534.KB906760_gene1243	5.368e-31	143.0	COG1629@1|root,COG1629@2|Bacteria,3Y98Z@57723|Acidobacteria,2JI5U@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_915625_8	1047013.AQSP01000088_gene1631	2.508e-24	118.0	COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria	2|Bacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_961483_6	401053.AciPR4_3363	1.243e-41	178.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_961483_4	1121033.AUCF01000003_gene3041	1.457e-53	199.0	COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,2TTXQ@28211|Alphaproteobacteria,2JWHU@204441|Rhodospirillales	204441|Rhodospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YYD3_k127_961483_9	234267.Acid_0082	2.149e-18	96.0	2FE51@1|root,3464Y@2|Bacteria,3Y8E0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_961483_2	234267.Acid_0081	1.787e-94	318.0	COG1409@1|root,COG1409@2|Bacteria,3Y6AF@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_961483_5	1267533.KB906737_gene1998	6.24e-46	175.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_961483_3	1037409.BJ6T_58620	1.59e-58	222.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
YYD3_k127_961483_0	1396141.BATP01000002_gene4802	1.599e-176	559.0	COG0387@1|root,COG0387@2|Bacteria,46UPT@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
YYD3_k127_961483_1	290397.Adeh_1659	1.601e-98	337.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
YYD3_k127_961483_10	1236973.JCM9157_840	2.014e-05	52.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus	91061|Bacilli	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
YYD3_k127_961483_7	1379698.RBG1_1C00001G0769	2.46e-37	162.0	COG3637@1|root,COG3637@2|Bacteria,2NQC8@2323|unclassified Bacteria	2|Bacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
YYD3_k127_961483_8	318167.Sfri_2638	1.064e-35	137.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria,2QAN2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
YYD3_k127_982041_4	485913.Krac_9361	2.253e-105	351.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
YYD3_k127_982041_3	391616.OA238_c14590	1.017e-118	401.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRW0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
YYD3_k127_982041_2	1382306.JNIM01000001_gene2428	2.347e-154	494.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
YYD3_k127_982041_1	1382306.JNIM01000001_gene2427	2.384e-196	621.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
YYD3_k127_982041_5	1382306.JNIM01000001_gene2426	8.261e-87	302.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_982041_0	1123020.AUIE01000021_gene1037	6.11e-245	765.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1YDZ3@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Catalyzes the formation of succinate from succinate semialdehyde	gabD	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2847,iYL1228.KPN_00256	Aldedh
YYD3_k127_982041_7	932678.THERU_02135	2.375e-22	108.0	COG2346@1|root,COG2346@2|Bacteria,2G5AF@200783|Aquificae	200783|Aquificae	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YYD3_k127_982041_6	329726.AM1_0833	1.013e-31	136.0	29Z8H@1|root,30M6K@2|Bacteria,1GGGV@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
YYD3_k127_996160_1	234267.Acid_2590	6.951e-103	346.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
YYD3_k127_996160_2	330214.NIDE4314	1.436e-99	333.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_996160_3	643648.Slip_0127	6.053e-53	199.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42JX4@68298|Syntrophomonadaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YYD3_k127_996160_0	204669.Acid345_0064	9.505e-261	814.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
## 3508 queries scanned
## Total time (seconds): 12.187525033950806
## Rate: 287.84 q/s