## Tue Mar 18 01:04:47 2025
## emapper-2.1.9
## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/YYD3_bin.21.fa -m mmseqs --itype genome -o YYD3_bin.21 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/YYD3_bin.21 --cpu 8
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
YYD3_k127_1004449_1	330214.NIDE0824	1.999e-131	421.0	COG1014@1|root,COG1014@2|Bacteria,3J0YE@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
YYD3_k127_1004449_0	330214.NIDE0823	4.527e-190	596.0	COG1013@1|root,COG1013@2|Bacteria,3J10F@40117|Nitrospirae	2|Bacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	forB2	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
YYD3_k127_1004449_2	330214.NIDE0820	1.076e-67	232.0	COG0780@1|root,COG0780@2|Bacteria,3J0R4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
YYD3_k127_1055059_2	204669.Acid345_0630	5.022e-15	80.0	COG1721@1|root,COG1721@2|Bacteria,3Y5V9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YYD3_k127_1055059_1	234267.Acid_0334	1.081e-91	328.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
YYD3_k127_1055059_0	682795.AciX8_1212	2.706e-135	447.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
YYD3_k127_1057234_5	345341.KUTG_07856	2.302e-06	55.0	COG2334@1|root,COG2334@2|Bacteria,2GXZI@201174|Actinobacteria,4E5SH@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD3_k127_1057234_3	1121918.ARWE01000001_gene3108	4.932e-88	298.0	COG0580@1|root,COG0580@2|Bacteria,1MZ47@1224|Proteobacteria	1224|Proteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
YYD3_k127_1057234_0	1042326.AZNV01000031_gene3669	3.058e-233	729.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,2UQIK@28211|Alphaproteobacteria,4BIGR@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
YYD3_k127_1057234_1	1173023.KE650771_gene4388	1.776e-214	679.0	COG0277@1|root,COG0277@2|Bacteria,1G207@1117|Cyanobacteria	1117|Cyanobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
YYD3_k127_1057234_4	388413.ALPR1_18483	8.464e-09	69.0	COG2382@1|root,COG2382@2|Bacteria,4NFZZ@976|Bacteroidetes,47TFB@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
YYD3_k127_1057234_2	1210884.HG799462_gene8936	1.69e-202	641.0	COG2931@1|root,COG2931@2|Bacteria,2IZ0P@203682|Planctomycetes	203682|Planctomycetes	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
YYD3_k127_1076669_4	292415.Tbd_1924	1.925e-14	76.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	ybaN	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
YYD3_k127_1076669_0	1267533.KB906737_gene1853	5.137e-181	578.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,3Y74D@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_1076669_1	234267.Acid_2160	3.367e-74	258.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_1076669_2	706587.Desti_5231	7.741e-41	170.0	COG1807@1|root,COG1807@2|Bacteria,1P7ER@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1076669_5	113395.AXAI01000003_gene5856	9.08e-11	73.0	COG3239@1|root,COG3239@2|Bacteria,1NIZS@1224|Proteobacteria,2UNUT@28211|Alphaproteobacteria,3K2D7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
YYD3_k127_1076669_3	882.DVU_3017	1.897e-24	115.0	COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,42TZQ@68525|delta/epsilon subdivisions,2WR01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_1076669_6	472759.Nhal_2907	1.984e-05	53.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
YYD3_k127_1090423_4	13689.BV96_03078	2.079e-10	64.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2U7JS@28211|Alphaproteobacteria,2K402@204457|Sphingomonadales	204457|Sphingomonadales	S	Hemerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD3_k127_1090423_2	1340493.JNIF01000003_gene2122	3.86e-20	98.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1090423_3	1267533.KB906736_gene902	4.244e-11	70.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_1090423_1	234267.Acid_3837	2.529e-47	191.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_1090423_5	689781.AUJX01000025_gene1524	9.502e-05	54.0	COG0657@1|root,COG1574@1|root,COG0657@2|Bacteria,COG1574@2|Bacteria,1TSMU@1239|Firmicutes,25KP7@186801|Clostridia,2PQMY@265975|Oribacterium	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YYD3_k127_1090423_0	97096.XP_007790920.1	1.083e-54	205.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_1090757_3	234267.Acid_2357	9.651e-20	89.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
YYD3_k127_1090757_1	1340493.JNIF01000003_gene2818	2.542e-37	153.0	COG0859@1|root,COG0859@2|Bacteria,3Y616@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD3_k127_1090757_0	335543.Sfum_3634	6.505e-88	301.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,2MQGF@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
YYD3_k127_1090757_2	1120936.KB907210_gene5545	5.396e-28	126.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4EHVT@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_1094869_5	868864.Dester_1526	1.026e-08	57.0	COG0750@1|root,COG0750@2|Bacteria,2G3QY@200783|Aquificae	200783|Aquificae	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
YYD3_k127_1094869_0	335543.Sfum_1784	4.576e-120	401.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MR0C@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
YYD3_k127_1094869_4	635013.TherJR_1363	4.731e-35	143.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia,267IB@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
YYD3_k127_1094869_1	234267.Acid_3241	1.403e-87	296.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
YYD3_k127_1094869_2	909663.KI867150_gene1890	2.769e-63	225.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
YYD3_k127_1094869_3	234267.Acid_5170	3.86e-56	202.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	lgtF	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
YYD3_k127_1108723_2	102125.Xen7305DRAFT_00036110	1.691e-155	504.0	COG1899@1|root,COG1899@2|Bacteria,1GHV9@1117|Cyanobacteria,3VN9Q@52604|Pleurocapsales	1117|Cyanobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
YYD3_k127_1108723_4	247490.KSU1_C0564	4.254e-54	198.0	COG1878@1|root,COG1878@2|Bacteria,2J1IQ@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
YYD3_k127_1108723_0	880073.Calab_0084	2.082e-176	562.0	COG0148@1|root,COG0148@2|Bacteria,2NNKW@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
YYD3_k127_1108723_6	471853.Bcav_4110	4.161e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,2IAMD@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SdrD_B
YYD3_k127_1108723_1	1267535.KB906767_gene1178	1.274e-162	542.0	28JZZ@1|root,2Z9PZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1108723_5	1166018.FAES_1171	1.364e-26	122.0	COG1082@1|root,COG1082@2|Bacteria,4NEUS@976|Bacteroidetes,47NHQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_1108723_3	1298867.AUES01000001_gene1607	3.197e-65	237.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,3JQU4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_1161193_9	278963.ATWD01000001_gene2369	9.497e-09	59.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YYD3_k127_1161193_3	1125863.JAFN01000001_gene2969	6.883e-98	334.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YYD3_k127_1161193_7	1303518.CCALI_01133	5.355e-14	79.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD3_k127_1161193_8	526222.Desal_0632	1.748e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WQ96@28221|Deltaproteobacteria,2MCPE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
YYD3_k127_1161193_0	1120973.AQXL01000133_gene1748	1.242e-163	528.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,278U9@186823|Alicyclobacillaceae	91061|Bacilli	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD3_k127_1161193_5	306281.AJLK01000113_gene488	2.01e-48	188.0	COG0277@1|root,COG0277@2|Bacteria,1G176@1117|Cyanobacteria,1JHZG@1189|Stigonemataceae	1117|Cyanobacteria	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD3_k127_1161193_1	1120973.AQXL01000133_gene1747	9.418e-112	374.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,278U1@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
YYD3_k127_1161193_2	443144.GM21_2282	7.468e-108	357.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,43T22@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YYD3_k127_1161193_4	28229.ND2E_4151	2.915e-82	281.0	COG3193@1|root,COG3193@2|Bacteria,1R215@1224|Proteobacteria,1S4R1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
YYD3_k127_1161193_6	861299.J421_5754	3.912e-40	158.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1163075_0	234267.Acid_7841	1.026e-143	492.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_1186546_1	78579.XP_003661026.1	5.061e-64	228.0	2EBD3@1|root,2SHGJ@2759|Eukaryota,39TQZ@33154|Opisthokonta,3NZP0@4751|Fungi,3QR77@4890|Ascomycota,218S5@147550|Sordariomycetes,3UABU@5139|Sordariales,3HAHA@35718|Chaetomiaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1186546_4	1340493.JNIF01000003_gene3749	1.224e-33	137.0	COG2041@1|root,COG2041@2|Bacteria,3Y5MM@57723|Acidobacteria	57723|Acidobacteria	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
YYD3_k127_1186546_3	290397.Adeh_1007	4.065e-37	143.0	COG3795@1|root,COG3795@2|Bacteria,1RH6U@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_1186546_2	234267.Acid_1209	2.961e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_1186546_0	234267.Acid_5217	2.587e-70	253.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
YYD3_k127_1186546_5	247633.GP2143_18121	1.38e-24	114.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1186546_6	1267533.KB906734_gene3979	1.108e-10	69.0	2A09E@1|root,30NCR@2|Bacteria,3Y8XP@57723|Acidobacteria,2JNU4@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1194280_1	97096.XP_007790920.1	5.629e-120	406.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_1194280_3	1120972.AUMH01000006_gene1809	3.138e-42	167.0	COG0657@1|root,COG0657@2|Bacteria,1UWRG@1239|Firmicutes,4I9QW@91061|Bacilli,27AB6@186823|Alicyclobacillaceae	91061|Bacilli	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
YYD3_k127_1194280_0	234267.Acid_1641	4.041e-123	405.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15,1.1.3.46	ko:K00104,ko:K16422	ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130	-	R00475,R06633	RC00042,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
YYD3_k127_1194280_2	288000.BBta_0150	4.106e-50	186.0	29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria,3JSSE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2585)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
YYD3_k127_1194280_5	237368.SCABRO_01869	1.404e-13	72.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YYD3_k127_1194280_4	96561.Dole_1902	7.142e-32	128.0	COG1848@1|root,COG1848@2|Bacteria,1N5DS@1224|Proteobacteria,43BCN@68525|delta/epsilon subdivisions,2X6RK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_1210698_2	234267.Acid_6299	1.055e-67	241.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
YYD3_k127_1210698_3	443143.GM18_1167	7.449e-35	135.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
YYD3_k127_1210698_0	1267533.KB906739_gene2555	5.941e-285	890.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
YYD3_k127_1210698_4	671143.DAMO_2924	0.0005045	47.0	2CBGA@1|root,33A66@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1210698_1	237368.SCABRO_01870	9.317e-174	562.0	COG0043@1|root,COG0043@2|Bacteria,2IYCA@203682|Planctomycetes	203682|Planctomycetes	H	COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
YYD3_k127_1220264_0	1384056.N787_11915	5.139e-67	232.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1X5E5@135614|Xanthomonadales	135614|Xanthomonadales	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2,TAT_signal
YYD3_k127_1220264_4	639030.JHVA01000001_gene1885	1.051e-17	87.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1220264_3	555793.WSK_4047	5.641e-32	136.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1220264_2	69395.JQLZ01000005_gene3645	1.37e-54	202.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_1220264_1	926566.Terro_1186	9.841e-67	256.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Z9@57723|Acidobacteria,2JKTJ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_1230843_1	1267535.KB906767_gene3728	2.393e-68	237.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_1230843_2	1382359.JIAL01000001_gene180	1.513e-28	125.0	COG2823@1|root,COG2823@2|Bacteria,3Y7Q9@57723|Acidobacteria,2JMV8@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_1230843_0	1519464.HY22_09305	1.674e-76	260.0	COG1945@1|root,COG1945@2|Bacteria,1FDKS@1090|Chlorobi	1090|Chlorobi	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
YYD3_k127_1230843_3	330214.NIDE0637	4.198e-13	72.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Amidohydro_1
YYD3_k127_1232527_0	205918.Psyr_4436	2.365e-126	408.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,1Z6UW@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha,Urease_beta
YYD3_k127_1232527_5	1173023.KE650771_gene4041	5.432e-14	78.0	COG2371@1|root,COG2371@2|Bacteria,1G6TF@1117|Cyanobacteria,1JIF6@1189|Stigonemataceae	1117|Cyanobacteria	O	UreE urease accessory protein, N-terminal domain	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
YYD3_k127_1232527_4	635013.TherJR_0609	8.387e-24	109.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia,262PC@186807|Peptococcaceae	186801|Clostridia	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
YYD3_k127_1232527_1	317936.Nos7107_2955	5.761e-94	312.0	COG0378@1|root,COG0378@2|Bacteria,1G0GT@1117|Cyanobacteria,1HJSE@1161|Nostocales	1117|Cyanobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	iJN678.ureG	cobW
YYD3_k127_1232527_3	562970.Btus_2189	5.22e-25	115.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,4HCED@91061|Bacilli,279TE@186823|Alicyclobacillaceae	91061|Bacilli	O	UreD urease accessory protein	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
YYD3_k127_1232527_2	204669.Acid345_4413	4.898e-28	117.0	COG1950@1|root,COG1950@2|Bacteria,3Y5FT@57723|Acidobacteria,2JJY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
YYD3_k127_1232527_6	1150398.JIBJ01000005_gene3267	6.531e-09	65.0	COG1670@1|root,COG1670@2|Bacteria,2IRHX@201174|Actinobacteria,1W9UM@1268|Micrococcaceae	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,GNAT_acetyltran
YYD3_k127_1232527_7	1205680.CAKO01000042_gene5480	6.636e-08	55.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,2JS1E@204441|Rhodospirillales	204441|Rhodospirillales	S	COG4422 Bacteriophage protein gp37	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
YYD3_k127_1233619_4	234267.Acid_4496	1.785e-16	82.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_1233619_1	215803.DB30_0689	3.022e-37	152.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2YYKM@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	CarS-like,Metallophos
YYD3_k127_1233619_0	1123371.ATXH01000010_gene700	1.93e-49	180.0	COG0432@1|root,COG0432@2|Bacteria,2GIHV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD3_k127_1233619_3	589873.EP13_13630	8.444e-17	93.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1233619_2	1101195.Meth11DRAFT_1464	5.095e-23	103.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_123497_2	247490.KSU1_D0564	5.804e-25	115.0	COG3824@1|root,COG3824@2|Bacteria,2J1JU@203682|Planctomycetes	203682|Planctomycetes	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
YYD3_k127_123497_0	234267.Acid_0769	4.636e-279	884.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,3Y61D@57723|Acidobacteria	57723|Acidobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
YYD3_k127_123497_1	234267.Acid_7363	4.48e-61	226.0	COG3359@1|root,COG3359@2|Bacteria,3Y6WT@57723|Acidobacteria	57723|Acidobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
YYD3_k127_1246035_2	1304888.ATWF01000001_gene2178	3.726e-27	113.0	COG0718@1|root,COG0718@2|Bacteria,2GFU9@200930|Deferribacteres	200930|Deferribacteres	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
YYD3_k127_1246035_0	204669.Acid345_1973	2.18e-75	257.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
YYD3_k127_1246035_1	234267.Acid_5377	2.056e-35	142.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YYD3_k127_1248650_4	1201288.M900_2568	1.865e-19	94.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YYD3_k127_1248650_6	682795.AciX8_1807	2.853e-11	76.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
YYD3_k127_1248650_1	234267.Acid_6348	7.04e-61	231.0	COG4219@1|root,COG4219@2|Bacteria,3Y5DY@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
YYD3_k127_1248650_2	234267.Acid_6347	6.677e-40	152.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_1248650_3	234267.Acid_5255	1.284e-33	136.0	2B11W@1|root,31TFA@2|Bacteria,3Y4Z8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1248650_0	172088.AUGA01000023_gene748	1.654e-87	299.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3JRVC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_1248650_5	314230.DSM3645_11242	5.541e-14	75.0	COG1520@1|root,COG1520@2|Bacteria,2IXKN@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_1253086_4	1396141.BATP01000019_gene1735	1.178e-20	107.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,46XFS@74201|Verrucomicrobia,2IVSV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD3_k127_1253086_5	1267533.KB906736_gene1246	1.902e-17	87.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_1253086_2	234267.Acid_7677	1.163e-56	203.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_1253086_0	234267.Acid_5749	3.808e-82	295.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1253086_1	1896.JOAU01000026_gene3380	5.255e-79	291.0	COG2730@1|root,COG3386@1|root,COG2730@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Cellulase,NHL,RicinB_lectin_2
YYD3_k127_1253086_3	358681.BBR47_24140	4.094e-23	116.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,274A1@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_1253086_6	661478.OP10G_3689	8.287e-09	57.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_125405_0	886293.Sinac_5331	5.587e-165	540.0	COG0249@1|root,COG0249@2|Bacteria,2IY9B@203682|Planctomycetes	203682|Planctomycetes	L	Mismatch repair ATPase (MutS family)	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
YYD3_k127_1286113_1	391615.ABSJ01000026_gene133	3.659e-115	398.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J4C2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_1286113_4	1267535.KB906767_gene2789	3.421e-29	130.0	COG2823@1|root,COG2823@2|Bacteria,3Y7TR@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1286113_0	1340493.JNIF01000004_gene621	4.973e-170	550.0	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Response_reg,Sigma54_activat
YYD3_k127_1286113_6	1198114.AciX9_0401	2.669e-17	91.0	COG3637@1|root,COG3637@2|Bacteria,3Y4YY@57723|Acidobacteria,2JJF4@204432|Acidobacteriia	204432|Acidobacteriia	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
YYD3_k127_1286113_2	1121918.ARWE01000001_gene3104	5.752e-96	328.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,43TCG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
YYD3_k127_1286113_3	1121918.ARWE01000001_gene3105	4.445e-35	137.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD3_k127_1291754_15	234267.Acid_3550	0.0008163	48.0	COG3832@1|root,COG3832@2|Bacteria,3Y7RQ@57723|Acidobacteria	57723|Acidobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD3_k127_1291754_2	234267.Acid_3551	9.279e-44	166.0	COG1309@1|root,COG1309@2|Bacteria,3Y4H4@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
YYD3_k127_1291754_3	1340493.JNIF01000003_gene4787	8.855e-34	140.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_1291754_13	1485545.JQLW01000010_gene1627	0.0001058	55.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YYD3_k127_1291754_1	580332.Slit_2488	4.768e-106	352.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2VM3P@28216|Betaproteobacteria,44W59@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD3_k127_1291754_8	61459.XP_007777273.1	1.567e-16	81.0	2EMXX@1|root,2SRGT@2759|Eukaryota,3A7B1@33154|Opisthokonta,3P5AS@4751|Fungi,3QXM4@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1291754_5	234267.Acid_1283	1.162e-27	119.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YYD3_k127_1291754_7	66692.ABC3499	9.966e-17	92.0	COG4188@1|root,COG4188@2|Bacteria,1V2UM@1239|Firmicutes,4IRIK@91061|Bacilli,1ZRUU@1386|Bacillus	91061|Bacilli	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
YYD3_k127_1291754_11	861299.J421_6284	2.731e-06	53.0	COG4242@1|root,COG4242@2|Bacteria,1ZTBM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
YYD3_k127_1291754_0	1485544.JQKP01000011_gene765	4.589e-119	398.0	COG0859@1|root,COG0859@2|Bacteria,1PRP7@1224|Proteobacteria,2VMYH@28216|Betaproteobacteria,44VET@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
YYD3_k127_1291754_6	926549.KI421517_gene3798	8.348e-25	118.0	COG5650@1|root,COG5650@2|Bacteria	2|Bacteria	M	phosphatidylinositol metabolic process	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2,PMT_4TMC,PRK
YYD3_k127_1291754_12	237368.SCABRO_01224	5.363e-05	55.0	2DBYC@1|root,2ZBUF@2|Bacteria,2IZ15@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YYD3_k127_1291754_9	234267.Acid_3437	4.719e-15	79.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD3_k127_1303497_5	886293.Sinac_3438	1.059e-128	427.0	COG4122@1|root,COG4122@2|Bacteria,2IXSM@203682|Planctomycetes	203682|Planctomycetes	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1303497_9	627192.SLG_31390	5.246e-99	342.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_1303497_1	234267.Acid_5827	9.676e-227	726.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_1303497_4	627192.SLG_31400	2.502e-140	458.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_1303497_6	1267535.KB906767_gene1576	2.296e-119	394.0	COG2010@1|root,COG2010@2|Bacteria,3Y7CN@57723|Acidobacteria,2JK7I@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_1303497_3	1267535.KB906767_gene1575	7.102e-202	642.0	COG2133@1|root,COG2133@2|Bacteria,3Y6R6@57723|Acidobacteria,2JMHE@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1303497_13	204773.HEAR0260	1.361e-37	153.0	COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VRTF@28216|Betaproteobacteria,473R4@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	2-keto-4-pentenoate hydratase	mhpD	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
YYD3_k127_1303497_11	96561.Dole_0534	4.776e-70	245.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MKSR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
YYD3_k127_1303497_0	1211115.ALIQ01000198_gene446	1.346e-241	754.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3NC6F@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD3_k127_1303497_10	234267.Acid_3888	6.338e-78	271.0	COG1413@1|root,COG1413@2|Bacteria,3Y8BY@57723|Acidobacteria	57723|Acidobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1303497_2	697282.Mettu_3364	1.635e-208	671.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XDS9@135618|Methylococcales	135618|Methylococcales	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD3_k127_1303497_12	483219.LILAB_29900	4.981e-48	175.0	COG1765@1|root,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria	1224|Proteobacteria	O	Redox protein regulator of disulfide bond formation	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
YYD3_k127_1303497_8	243090.RB13273	9.925e-108	358.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
YYD3_k127_1303497_7	330214.NIDE0474	1.018e-114	380.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
YYD3_k127_1312604_0	234267.Acid_5331	1.904e-205	659.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YYD3_k127_1317275_9	1242864.D187_006714	6.332e-36	146.0	29AFQ@1|root,2ZXFW@2|Bacteria,1RGFB@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
YYD3_k127_1317275_1	234267.Acid_7174	1.859e-84	291.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YYD3_k127_1317275_10	1120951.AUBG01000004_gene2526	7.857e-34	138.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1HYWY@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD3_k127_1317275_0	525897.Dbac_1184	1.497e-195	622.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
YYD3_k127_1317275_7	1132855.KB913035_gene2388	1.916e-61	216.0	COG2193@1|root,COG2193@2|Bacteria,1RF3C@1224|Proteobacteria,2VRIX@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the Dps family	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD3_k127_1317275_3	1469557.JSWF01000028_gene2845	2.343e-75	264.0	COG2234@1|root,COG2234@2|Bacteria,4NMZ4@976|Bacteroidetes,1HWZ9@117743|Flavobacteriia	976|Bacteroidetes	OU	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD3_k127_1317275_6	314278.NB231_02123	2.047e-67	235.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,1T04E@1236|Gammaproteobacteria,1X2KR@135613|Chromatiales	135613|Chromatiales	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
YYD3_k127_1317275_5	671143.DAMO_2078	6.545e-70	247.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YYD3_k127_1317275_8	234267.Acid_5168	4.164e-39	147.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria	57723|Acidobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YYD3_k127_1317275_4	1382359.JIAL01000001_gene721	5.388e-71	245.0	COG0717@1|root,COG0717@2|Bacteria,3Y42N@57723|Acidobacteria,2JIA0@204432|Acidobacteriia	204432|Acidobacteriia	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
YYD3_k127_1317275_2	247490.KSU1_C1590	2.426e-80	273.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD3_k127_1346496_1	443144.GM21_3186	3.149e-79	270.0	COG1215@1|root,COG1215@2|Bacteria,1R4ZM@1224|Proteobacteria,42T5P@68525|delta/epsilon subdivisions,2WPSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_1346496_0	443144.GM21_3187	1.708e-136	447.0	COG1331@1|root,COG1331@2|Bacteria,1RC7D@1224|Proteobacteria,42X60@68525|delta/epsilon subdivisions,2WTDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1346496_2	395495.Lcho_1385	8.151e-20	90.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2WFJ1@28216|Betaproteobacteria,1KJTK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
YYD3_k127_1359943_6	504472.Slin_2709	0.0005938	46.0	COG1595@1|root,COG1595@2|Bacteria,4NP91@976|Bacteroidetes,47PTK@768503|Cytophagia	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1359943_1	234267.Acid_3837	9.491e-53	207.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_1359943_2	639030.JHVA01000001_gene3441	5.791e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,3Y536@57723|Acidobacteria,2JJK1@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_1359943_4	401053.AciPR4_0694	3.304e-12	75.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
YYD3_k127_1359943_0	314278.NB231_00265	4.811e-94	315.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria,1X0JC@135613|Chromatiales	135613|Chromatiales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_1359943_3	768066.HELO_2152	7.832e-19	91.0	COG3324@1|root,COG3324@2|Bacteria,1N3NT@1224|Proteobacteria,1S9KH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_1368022_7	671143.DAMO_1659	1.271e-33	138.0	COG0109@1|root,COG0109@2|Bacteria,2NPBW@2323|unclassified Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iJN746.PP_0110,iSB619.SA_RS05465,iSFxv_1172.SFxv_0410,iYO844.BSU12080	UbiA
YYD3_k127_1368022_4	481448.Minf_1426	2.04e-56	209.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
YYD3_k127_1368022_5	926566.Terro_0968	1.458e-45	174.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_1368022_0	1353529.M899_0208	2.03e-165	556.0	COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2MUN1@213481|Bdellovibrionales,2WPS4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_1368022_2	1123242.JH636438_gene5694	2.014e-126	414.0	COG1290@1|root,COG1290@2|Bacteria,2IYI0@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
YYD3_k127_1368022_1	862908.BMS_0208	5.357e-128	415.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome b b6 domain	pcmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
YYD3_k127_1368022_3	886293.Sinac_1829	1.283e-59	214.0	COG0723@1|root,COG0723@2|Bacteria,2IZ3E@203682|Planctomycetes	203682|Planctomycetes	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
YYD3_k127_1368022_8	410358.Mlab_0517	8.677e-06	57.0	arCOG04006@1|root,arCOG04006@2157|Archaea	2157|Archaea	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YYD3_k127_1368022_6	189753.AXAS01000036_gene7763	3.318e-42	160.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3JUE1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
YYD3_k127_1389261_1	861299.J421_1100	4.184e-127	416.0	COG3391@1|root,COG3391@2|Bacteria,1ZT41@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1389261_2	1038862.KB893836_gene1437	2.438e-63	237.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JS0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	repeat protein	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1389261_3	1121413.JMKT01000010_gene710	3.254e-61	220.0	COG4912@1|root,COG4912@2|Bacteria,1QSBJ@1224|Proteobacteria,42QNI@68525|delta/epsilon subdivisions,2WN26@28221|Deltaproteobacteria,2MFNW@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YYD3_k127_1389261_4	344747.PM8797T_10809	4.455e-25	109.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
YYD3_k127_1389261_0	234267.Acid_5749	1.154e-155	517.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_1408299_4	404380.Gbem_3990	1.304e-06	58.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YkuD
YYD3_k127_1408299_1	335543.Sfum_2294	7.697e-53	205.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,43C9W@68525|delta/epsilon subdivisions,2X7KC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Transduction Histidine Kinase	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE2,HATPase_c,HisKA
YYD3_k127_1408299_0	240015.ACP_0677	5.453e-135	445.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_1408299_2	234267.Acid_6789	8.972e-26	118.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1408299_3	1304885.AUEY01000012_gene1826	2.809e-18	87.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_1431976_1	1267533.KB906737_gene1587	1.363e-82	281.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YYD3_k127_1431976_0	1267535.KB906767_gene3956	1.065e-139	454.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
YYD3_k127_1431976_2	639282.DEFDS_0269	1.342e-42	161.0	COG0242@1|root,COG0242@2|Bacteria,2GFNS@200930|Deferribacteres	200930|Deferribacteres	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
YYD3_k127_1449575_1	1210884.HG799479_gene15512	9.257e-15	81.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
YYD3_k127_1449575_0	742743.HMPREF9453_01655	8.903e-17	89.0	COG3335@1|root,COG3335@2|Bacteria,1VQBP@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
YYD3_k127_1449575_2	1502852.FG94_03081	2.195e-10	64.0	COG0784@1|root,COG0784@2|Bacteria,1QZE2@1224|Proteobacteria,2VU92@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_146412_0	1037409.BJ6T_40350	4.634e-137	440.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JUB5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
YYD3_k127_146412_3	379066.GAU_2821	3.549e-72	261.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_146412_1	1123508.JH636445_gene6496	1.805e-131	435.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
YYD3_k127_146412_2	1123242.JH636434_gene3999	6.736e-127	421.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
YYD3_k127_146412_4	264462.Bd0818	6.842e-33	137.0	COG1285@1|root,COG1285@2|Bacteria,1RAIG@1224|Proteobacteria,42T1T@68525|delta/epsilon subdivisions,2WPMM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
YYD3_k127_146412_7	1192034.CAP_3217	8.38e-19	95.0	COG5036@1|root,COG5036@2|Bacteria,1RG06@1224|Proteobacteria,42RP7@68525|delta/epsilon subdivisions,2WNHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
YYD3_k127_146412_5	401053.AciPR4_2577	4.138e-26	111.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_146412_6	402777.KB235904_gene4127	6.558e-19	88.0	COG2066@1|root,COG2066@2|Bacteria,1G1IK@1117|Cyanobacteria,1H7V2@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase,STAS,cNMP_binding
YYD3_k127_1471709_0	234267.Acid_0734	2.25e-76	263.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD3_k127_1471709_4	41875.XP_007515304.1	7.234e-33	134.0	COG0576@1|root,KOG3003@2759|Eukaryota,37INI@33090|Viridiplantae,34M0C@3041|Chlorophyta	3041|Chlorophyta	O	Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner	CGE1	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
YYD3_k127_1471709_1	204669.Acid345_3244	1.812e-59	219.0	COG1420@1|root,COG1420@2|Bacteria,3Y2JI@57723|Acidobacteria,2JI0D@204432|Acidobacteriia	204432|Acidobacteriia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
YYD3_k127_1471709_2	1128421.JAGA01000002_gene32	3.051e-47	179.0	COG0095@1|root,COG0095@2|Bacteria,2NPP1@2323|unclassified Bacteria	2|Bacteria	H	Biotin/lipoate A/B protein ligase family	lipM	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
YYD3_k127_1471709_3	682795.AciX8_1315	9.523e-37	148.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria,2JI16@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_1485513_2	290397.Adeh_3481	4.526e-11	63.0	COG4783@1|root,COG4783@2|Bacteria,1QYGM@1224|Proteobacteria,43CCT@68525|delta/epsilon subdivisions,2X7NP@28221|Deltaproteobacteria,2Z3H5@29|Myxococcales	28221|Deltaproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_1485513_0	867903.ThesuDRAFT_00352	7.756e-260	820.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
YYD3_k127_1485513_1	234267.Acid_7894	2.428e-21	100.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
YYD3_k127_1493633_3	316067.Geob_0803	1.552e-68	243.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YYD3_k127_1493633_6	313612.L8106_00945	2.434e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,1G3VQ@1117|Cyanobacteria,1H9K3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
YYD3_k127_1493633_2	1379698.RBG1_1C00001G0560	1.395e-75	261.0	COG0483@1|root,COG0483@2|Bacteria,2NP94@2323|unclassified Bacteria	2|Bacteria	G	Inositol monophosphatase	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
YYD3_k127_1493633_0	204669.Acid345_3439	2.646e-143	475.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
YYD3_k127_1493633_4	391623.TERMP_01541	9.026e-61	218.0	COG0274@1|root,arCOG04320@2157|Archaea,2XT2D@28890|Euryarchaeota,242NJ@183968|Thermococci	183968|Thermococci	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
YYD3_k127_1493633_5	665956.HMPREF1032_01440	2.407e-50	184.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
YYD3_k127_1493633_8	118168.MC7420_817	1.421e-09	69.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G0YS@1117|Cyanobacteria,1H82I@1150|Oscillatoriales	1117|Cyanobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
YYD3_k127_1493633_1	1499967.BAYZ01000196_gene3073	9.568e-134	439.0	COG2379@1|root,COG2379@2|Bacteria,2NNQP@2323|unclassified Bacteria	2|Bacteria	G	MOFRL family	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
YYD3_k127_1493633_7	926569.ANT_11960	1.393e-13	70.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
YYD3_k127_1508292_1	985053.VMUT_1519	3.776e-23	103.0	COG1917@1|root,arCOG02999@2157|Archaea	2157|Archaea	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_1508292_2	1415754.JQMK01000002_gene2476	6.25e-07	58.0	2F9VU@1|root,3425C@2|Bacteria,1NXNW@1224|Proteobacteria,1SPVX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YYD3_k127_1508292_0	264462.Bd3085	3.703e-86	291.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2MSRT@213481|Bdellovibrionales,2WIS7@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,Oxidored_q6
YYD3_k127_1512032_5	1267533.KB906734_gene4338	3.449e-47	171.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD3_k127_1512032_0	1382304.JNIL01000001_gene614	9.333e-155	501.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,277XV@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
YYD3_k127_1512032_4	290397.Adeh_2654	2.674e-55	204.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
YYD3_k127_1512032_3	316067.Geob_0753	1.37e-74	261.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD3_k127_1512032_12	998674.ATTE01000001_gene3798	1.839e-08	62.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_1512032_11	314345.SPV1_10991	4.747e-25	108.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria	1224|Proteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
YYD3_k127_1512032_6	1267533.KB906741_gene415	1.475e-37	142.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
YYD3_k127_1512032_1	234267.Acid_3160	1.215e-129	422.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
YYD3_k127_1512032_8	888439.HMPREF9240_00223	5.308e-33	136.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4D331@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD3_k127_1512032_10	1499967.BAYZ01000165_gene6647	6.395e-28	119.0	COG0799@1|root,COG0799@2|Bacteria,2NPYI@2323|unclassified Bacteria	2|Bacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RsfS
YYD3_k127_1512032_9	269799.Gmet_3202	3.189e-31	127.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
YYD3_k127_1512032_7	243231.GSU0124	1.539e-37	149.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
YYD3_k127_1512032_2	204669.Acid345_0085	6e-90	306.0	COG0774@1|root,COG0774@2|Bacteria,3Y40I@57723|Acidobacteria,2JI1R@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
YYD3_k127_1518826_3	247490.KSU1_D0370	1.155e-51	198.0	COG3320@1|root,COG3320@2|Bacteria,2IXFT@203682|Planctomycetes	203682|Planctomycetes	Q	dehydrogenase domain of multifunctional non-ribosomal peptide	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
YYD3_k127_1518826_5	485913.Krac_11897	3.782e-26	121.0	COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase 28 domain	-	-	2.4.1.46	ko:K03715	ko00561,ko01100,map00561,map01100	-	R02691	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
YYD3_k127_1518826_4	760192.Halhy_4503	2.857e-38	150.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
YYD3_k127_1518826_0	391625.PPSIR1_32512	2.612e-139	454.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
YYD3_k127_1518826_2	379066.GAU_2821	8.414e-94	321.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1518826_1	471854.Dfer_2856	2.664e-105	359.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_1547072_0	1267533.KB906733_gene3596	5.626e-177	561.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	2|Bacteria	J	class II (D K	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759,ko:K22503	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD3_k127_1547072_1	1907.SGLAU_31165	3.264e-107	360.0	COG0454@1|root,COG0456@2|Bacteria,2I39R@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
YYD3_k127_1547072_2	1116375.VEJY3_07780	8.972e-47	173.0	COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,1SAAN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
YYD3_k127_1547072_3	234267.Acid_3837	3.535e-31	135.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_1549852_10	401053.AciPR4_3988	4.116e-05	48.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD3_k127_1549852_9	1121451.DESAM_10058	1.25e-09	68.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2MBW2@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YYD3_k127_1549852_6	290397.Adeh_1084	4.188e-44	165.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2YVDF@29|Myxococcales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
YYD3_k127_1549852_4	1267533.KB906734_gene4090	2.513e-82	281.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria,2JI06@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
YYD3_k127_1549852_2	204669.Acid345_4554	3.962e-94	317.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
YYD3_k127_1549852_1	204669.Acid345_0232	1.252e-94	319.0	COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria,2JHRR@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
YYD3_k127_1549852_8	1340493.JNIF01000003_gene3597	2.451e-20	103.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
YYD3_k127_1549852_5	903818.KI912268_gene674	1.345e-55	216.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
YYD3_k127_1549852_3	234267.Acid_1297	3.95e-83	287.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
YYD3_k127_1549852_7	240015.ACP_1035	4.475e-23	100.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria,2JJSQ@204432|Acidobacteriia	204432|Acidobacteriia	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
YYD3_k127_1549852_0	767817.Desgi_4663	3.231e-102	344.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
YYD3_k127_1557081_5	1123236.KB899377_gene78	1.705e-05	54.0	COG3595@1|root,COG3595@2|Bacteria,1RFCY@1224|Proteobacteria,1S5RB@1236|Gammaproteobacteria,467PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YYD3_k127_1557081_3	1267535.KB906767_gene4065	1.732e-22	108.0	COG1413@1|root,COG1413@2|Bacteria,3Y2TB@57723|Acidobacteria	57723|Acidobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
YYD3_k127_1557081_1	278963.ATWD01000001_gene3390	1.366e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,3Y4CH@57723|Acidobacteria,2JJ6R@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD3_k127_1557081_0	204669.Acid345_0549	1.687e-123	417.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria,2JHZB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YYD3_k127_1557081_2	234267.Acid_3837	3.372e-46	189.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_1557081_4	204669.Acid345_0913	1.599e-07	55.0	COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1574090_9	234267.Acid_4323	9.585e-38	161.0	COG4219@1|root,COG4219@2|Bacteria,3Y5JT@57723|Acidobacteria	57723|Acidobacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
YYD3_k127_1574090_8	234267.Acid_4324	2.952e-41	156.0	COG3682@1|root,COG3682@2|Bacteria,3Y573@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_1574090_3	1123367.C666_01500	1.245e-107	354.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2VK6T@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
YYD3_k127_1574090_1	204669.Acid345_1273	8.152e-213	668.0	COG1690@1|root,COG1690@2|Bacteria,3Y82C@57723|Acidobacteria,2JN64@204432|Acidobacteriia	204432|Acidobacteriia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
YYD3_k127_1574090_2	234267.Acid_7272	1.077e-149	486.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
YYD3_k127_1574090_0	234267.Acid_1492	1.049e-253	790.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD3_k127_1574090_5	1321784.HMPREF1987_02271	2.696e-88	296.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YYD3_k127_1574090_11	1183438.GKIL_1763	5.64e-27	128.0	2EA12@1|root,3346D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
YYD3_k127_1574090_4	1079460.ATTQ01000032_gene3960	1.033e-94	325.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2U0DX@28211|Alphaproteobacteria,4B8D0@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_1574090_12	330214.NIDE2854	9.911e-24	116.0	COG0438@1|root,COG0438@2|Bacteria,3J15E@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_1574090_10	234267.Acid_6619	2.945e-35	155.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	PglL_A,Wzy_C,Wzy_C_2
YYD3_k127_1574090_14	448385.sce6683	1.108e-12	81.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,42MH6@68525|delta/epsilon subdivisions,2WKH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
YYD3_k127_1574090_15	1209989.TepiRe1_1918	8.748e-10	71.0	COG3206@1|root,COG3206@2|Bacteria,1TSJG@1239|Firmicutes,249MI@186801|Clostridia,42ENX@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
YYD3_k127_1574090_6	717605.Theco_3900	1.049e-80	290.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,26T0Q@186822|Paenibacillaceae	91061|Bacilli	M	glucose phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
YYD3_k127_1574090_7	1198114.AciX9_0588	4.845e-43	174.0	COG1596@1|root,COG1596@2|Bacteria,3Y4ZJ@57723|Acidobacteria,2JJKP@204432|Acidobacteriia	204432|Acidobacteriia	M	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
YYD3_k127_1574090_13	861299.J421_0839	1.881e-17	94.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
YYD3_k127_1597186_0	234267.Acid_7035	0.0	1197.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YYD3_k127_1597186_1	1123508.JH636442_gene4251	2.171e-115	382.0	COG4307@1|root,COG4307@2|Bacteria,2IXC4@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
YYD3_k127_1597186_3	926567.TheveDRAFT_1038	6.445e-37	148.0	COG0041@1|root,COG0041@2|Bacteria,3TB8R@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
YYD3_k127_1597186_2	32057.KB217479_gene7714	2.071e-96	340.0	COG0028@1|root,COG2931@1|root,COG0028@2|Bacteria,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
YYD3_k127_1600390_2	1122226.AUHX01000001_gene558	1.612e-74	281.0	COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
YYD3_k127_1600390_1	1122164.JHWF01000020_gene1466	9.331e-114	381.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria,1JEAP@118969|Legionellales	118969|Legionellales	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
YYD3_k127_1600390_0	113395.AXAI01000004_gene4585	6.684e-308	946.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2TVQ7@28211|Alphaproteobacteria,3JWEV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	HpaB,HpaB_N
YYD3_k127_1600390_3	279238.Saro_2953	2.349e-36	140.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,2K4B3@204457|Sphingomonadales	204457|Sphingomonadales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
YYD3_k127_1605888_1	1173022.Cri9333_0076	0.0001268	44.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_1605888_0	234267.Acid_6302	4.363e-82	286.0	COG1216@1|root,COG1216@2|Bacteria,3Y5FE@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_1606802_1	1210884.HG799469_gene14163	3.132e-101	344.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_1606802_0	1340493.JNIF01000003_gene2812	0.0	1734.0	COG3459@1|root,COG3459@2|Bacteria,3Y3E9@57723|Acidobacteria	57723|Acidobacteria	G	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
YYD3_k127_1609388_3	1187851.A33M_2392	2.103e-35	135.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,3FCSH@34008|Rhodovulum	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YYD3_k127_1609388_1	1163408.UU9_08290	8.006e-57	205.0	2ANK7@1|root,31DJB@2|Bacteria,1R2CN@1224|Proteobacteria	1224|Proteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
YYD3_k127_1609388_4	748247.AZKH_0458	1.432e-21	98.0	COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2VVR6@28216|Betaproteobacteria,2KXHZ@206389|Rhodocyclales	206389|Rhodocyclales	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD3_k127_1609388_0	381666.H16_B2250	4.315e-123	406.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1609388_2	661478.OP10G_3842	3.912e-39	156.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
YYD3_k127_1623502_0	1444712.BN1013_01440	6.538e-229	722.0	COG0187@1|root,COG0187@2|Bacteria,2JFGD@204428|Chlamydiae	204428|Chlamydiae	L	DNA topoisomerase (ATP-hydrolyzing)	parE	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
YYD3_k127_1634832_1	443143.GM18_2371	5.941e-05	48.0	COG4980@1|root,COG4980@2|Bacteria,1NEPD@1224|Proteobacteria,42WE2@68525|delta/epsilon subdivisions,2WRDT@28221|Deltaproteobacteria,43SRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
YYD3_k127_1634832_0	234267.Acid_3174	2.319e-10	65.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_1637750_2	1232410.KI421413_gene791	1.734e-09	58.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,42NM4@68525|delta/epsilon subdivisions,2WJ8H@28221|Deltaproteobacteria,43VYC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	3.8.1.5	ko:K01563,ko:K22318	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YYD3_k127_1637750_1	1117379.BABA_13992	1.194e-27	115.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	yjcS	GO:0003674,GO:0003824	-	-	-	-	-	-	-	-	-	-	ABM
YYD3_k127_1637750_4	243231.GSU1343	0.0001028	47.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42Q9J@68525|delta/epsilon subdivisions,2WKMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YYD3_k127_1637750_0	1509405.GV67_19470	2.27e-96	320.0	COG1335@1|root,COG1335@2|Bacteria,1MWFQ@1224|Proteobacteria,2U8F9@28211|Alphaproteobacteria,4BMX4@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
YYD3_k127_1637750_3	680198.SCAB_2451	3.157e-07	54.0	COG3224@1|root,COG3224@2|Bacteria,2GY26@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
YYD3_k127_1644108_6	1121287.AUMU01000016_gene130	2.477e-28	115.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1I0M1@117743|Flavobacteriia,3ZPRB@59732|Chryseobacterium	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD3_k127_1644108_0	192952.MM_1461	0.0	1243.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,2NAFK@224756|Methanomicrobia	28890|Euryarchaeota	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpA	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
YYD3_k127_1644108_3	278963.ATWD01000002_gene397	6.715e-113	375.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria,2JI2Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
YYD3_k127_1644108_4	933262.AXAM01000015_gene116	1.45e-110	378.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MIBD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YYD3_k127_1644108_5	1111479.AXAR01000003_gene1722	1.245e-90	315.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,277XE@186823|Alicyclobacillaceae	91061|Bacilli	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
YYD3_k127_1644108_1	234267.Acid_5274	4.475e-176	558.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
YYD3_k127_1644108_2	204669.Acid345_1515	1.551e-127	435.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
YYD3_k127_1681027_3	1382306.JNIM01000001_gene274	1.944e-19	90.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
YYD3_k127_1681027_2	215803.DB30_7638	5.39e-28	122.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YYD3_k127_1681027_0	867903.ThesuDRAFT_00167	6.191e-45	170.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WCIP@538999|Clostridiales incertae sedis	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
YYD3_k127_1681027_5	56780.SYN_01756	1.881e-09	68.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria	1224|Proteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
YYD3_k127_1681027_4	204669.Acid345_2059	2.557e-18	87.0	COG1923@1|root,COG1923@2|Bacteria,3Y5PK@57723|Acidobacteria,2JJYT@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
YYD3_k127_1681027_1	331113.SNE_A09320	4.116e-30	127.0	COG1011@1|root,COG1011@2|Bacteria,2JHBS@204428|Chlamydiae	204428|Chlamydiae	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD3_k127_1681230_5	234267.Acid_5050	3.395e-47	188.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M,NPCBM,Peptidase_M16,Peptidase_M16_C
YYD3_k127_1681230_10	1236959.BAMT01000015_gene2850	1.994e-17	96.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1681230_4	136993.KB900627_gene392	5.457e-70	248.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1681230_9	1101195.Meth11DRAFT_1464	3.724e-19	94.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1681230_12	1122132.AQYH01000010_gene3737	4.355e-10	67.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria,2UEZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1681230_6	682795.AciX8_2361	4.478e-45	178.0	COG3182@1|root,COG3182@2|Bacteria,3Y2R7@57723|Acidobacteria,2JIBB@204432|Acidobacteriia	204432|Acidobacteriia	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
YYD3_k127_1681230_13	1499967.BAYZ01000036_gene2434	4.01e-09	62.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
YYD3_k127_1681230_2	595537.Varpa_2578	2.42e-198	625.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria,4ABS2@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	ligB	-	1.13.11.57	ko:K04099	ko00627,ko01120,map00627,map01120	-	R03550,R04280,R09565	RC00233,RC00535,RC02567,RC02694	ko00000,ko00001,ko01000	-	-	-	LigA,LigB
YYD3_k127_1681230_8	1380384.JADN01000004_gene2075	2.79e-22	104.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1I1YR@117743|Flavobacteriia	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
YYD3_k127_1681230_7	1278309.KB907105_gene1385	1.715e-30	124.0	2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
YYD3_k127_1681230_3	909663.KI867150_gene335	1.898e-153	505.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,42NAM@68525|delta/epsilon subdivisions,2WJTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HlyD_3,HlyD_D23
YYD3_k127_1681230_0	330214.NIDE2723	1.807e-226	722.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	yydH	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,PqqD
YYD3_k127_1681230_1	909663.KI867150_gene333	2.899e-218	695.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MQB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
YYD3_k127_1681230_11	639030.JHVA01000001_gene1872	6.926e-17	94.0	COG1538@1|root,COG1538@2|Bacteria,3Y3BF@57723|Acidobacteria,2JIVR@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD3_k127_1681230_14	1254432.SCE1572_48120	1.187e-05	54.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2YUR4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD3_k127_1687590_1	69042.WH5701_11169	8.424e-48	184.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
YYD3_k127_1687590_2	211114.JOEF01000018_gene6189	1.709e-12	77.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4E735@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1687590_0	762376.AXYL_02523	1.922e-167	547.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2W101@28216|Betaproteobacteria,3T3FI@506|Alcaligenaceae	28216|Betaproteobacteria	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
YYD3_k127_1688950_11	1120951.AUBG01000027_gene1832	1.035e-46	169.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1688950_16	1280663.ATVR01000007_gene1881	0.0001273	45.0	29TS8@1|root,30F0H@2|Bacteria,1UD83@1239|Firmicutes,25HVT@186801|Clostridia,4C0IE@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1688950_9	1173027.Mic7113_0657	1.784e-60	215.0	COG4894@1|root,COG4894@2|Bacteria,1G3DI@1117|Cyanobacteria,1HFBY@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1688950_7	1117647.M5M_15900	5.679e-71	245.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria,1JA28@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
YYD3_k127_1688950_14	179408.Osc7112_3830	1.04e-22	107.0	28MPS@1|root,2ZAYV@2|Bacteria,1G3FU@1117|Cyanobacteria,1H8EW@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1688950_13	317936.Nos7107_3034	2.394e-23	105.0	COG0614@1|root,COG0614@2|Bacteria,1G73G@1117|Cyanobacteria,1HNPK@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
YYD3_k127_1688950_12	323261.Noc_0762	4.987e-44	169.0	COG4636@1|root,COG4636@2|Bacteria,1RJC2@1224|Proteobacteria,1S7B0@1236|Gammaproteobacteria,1X14J@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_1688950_5	1003200.AXXA_30032	3.537e-86	294.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,3T3A0@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YYD3_k127_1688950_4	546271.Selsp_0476	2.204e-91	310.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4H1WJ@909932|Negativicutes	909932|Negativicutes	E	ABC transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
YYD3_k127_1688950_3	1379698.RBG1_1C00001G1349	1.919e-93	320.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YYD3_k127_1688950_2	1379698.RBG1_1C00001G1350	1.334e-99	336.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
YYD3_k127_1688950_1	1379698.RBG1_1C00001G1351	9.738e-142	462.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
YYD3_k127_1688950_10	1340493.JNIF01000003_gene3793	3.97e-52	191.0	COG2010@1|root,COG2010@2|Bacteria,3Y8CD@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1688950_6	234267.Acid_3773	1.578e-75	265.0	COG2372@1|root,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	-	-	3.2.1.20	ko:K01187,ko:K16915	ko00052,ko00500,ko01100,ko02010,map00052,map00500,map01100,map02010	M00246	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02000	-	GH31	-	Big_5
YYD3_k127_1688950_8	497965.Cyan7822_3076	8.75e-67	245.0	COG2199@1|root,COG3447@1|root,COG2199@2|Bacteria,COG3447@2|Bacteria,1GD2B@1117|Cyanobacteria,3KJWM@43988|Cyanothece	1117|Cyanobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
YYD3_k127_1688950_0	204669.Acid345_3937	7.202e-183	581.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K06958,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03019	-	-	-	APH,ATP_bind_2
YYD3_k127_1699326_1	1408254.T458_20775	8.075e-115	381.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
YYD3_k127_1699326_0	682795.AciX8_1044	4.871e-173	561.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria,2JI29@204432|Acidobacteriia	204432|Acidobacteriia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
YYD3_k127_1699326_3	1191523.MROS_1415	8.436e-25	106.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
YYD3_k127_1699326_2	1242864.D187_003261	3.259e-57	208.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
YYD3_k127_1700416_4	1121935.AQXX01000138_gene3156	1.602e-08	67.0	2A1MP@1|root,30PVX@2|Bacteria,1R4FS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1700416_2	1207076.ALAT01000033_gene3772	1.78e-90	307.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria,1Z1GG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	Copper resistance	copB	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
YYD3_k127_1700416_1	1045855.DSC_03735	3.463e-259	811.0	COG2132@1|root,COG3667@1|root,COG2132@2|Bacteria,COG3667@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1X3SD@135614|Xanthomonadales	135614|Xanthomonadales	Q	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
YYD3_k127_1700416_5	1156937.MFUM_940020	2.251e-06	55.0	28T88@1|root,2ZFGX@2|Bacteria,46Z1A@74201|Verrucomicrobia,37H1B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1700416_3	1156937.MFUM_940021	2.446e-55	199.0	COG2010@1|root,COG2010@2|Bacteria,46WD1@74201|Verrucomicrobia,37GQ1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_1700416_0	886293.Sinac_2520	5e-324	1009.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
YYD3_k127_175225_6	1267534.KB906755_gene4457	7.923e-15	86.0	COG5485@1|root,COG5485@2|Bacteria,3Y7UD@57723|Acidobacteria,2JN18@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD3_k127_175225_3	1183438.GKIL_0035	7.738e-54	203.0	COG2085@1|root,COG2085@2|Bacteria,1G8DX@1117|Cyanobacteria	1117|Cyanobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
YYD3_k127_175225_7	401053.AciPR4_1170	3.183e-08	56.0	2EFZF@1|root,339RM@2|Bacteria,3Y5X5@57723|Acidobacteria,2JK63@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_175225_2	234267.Acid_2955	2.963e-62	222.0	2FBCE@1|root,343I9@2|Bacteria,3Y8Q4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_175225_1	234267.Acid_2953	1.611e-68	248.0	COG2304@1|root,COG2304@2|Bacteria,3Y7U1@57723|Acidobacteria	2|Bacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
YYD3_k127_175225_5	1267535.KB906767_gene2939	1.466e-35	144.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria,2JNIT@204432|Acidobacteriia	204432|Acidobacteriia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
YYD3_k127_175225_4	1499967.BAYZ01000009_gene5396	8.333e-36	139.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
YYD3_k127_175225_0	234267.Acid_6747	2.286e-149	481.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD3_k127_17567_1	658187.LDG_7561	4.15e-103	344.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1JFIW@118969|Legionellales	118969|Legionellales	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,RMMBL
YYD3_k127_17567_2	1227349.C170_29228	6.624e-84	294.0	COG0154@1|root,COG0154@2|Bacteria,1TR9X@1239|Firmicutes,4HAYP@91061|Bacilli,271R1@186822|Paenibacillaceae	91061|Bacilli	J	Amidase	gatA3	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_17567_0	234267.Acid_2729	8.55e-108	361.0	28K3C@1|root,2Z9SH@2|Bacteria,3Y7UF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_17567_3	234267.Acid_2730	9.68e-82	284.0	28PTH@1|root,2ZCER@2|Bacteria,3Y860@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_17567_4	234267.Acid_2620	1.037e-80	274.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1796882_5	1267535.KB906767_gene553	5.582e-26	119.0	COG0666@1|root,COG2815@1|root,COG0666@2|Bacteria,COG2815@2|Bacteria,3Y88E@57723|Acidobacteria,2JND4@204432|Acidobacteriia	204432|Acidobacteriia	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
YYD3_k127_1796882_2	861299.J421_5754	6.115e-73	258.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1796882_1	1123242.JH636436_gene659	5.776e-81	284.0	COG1819@1|root,COG1819@2|Bacteria,2IZT0@203682|Planctomycetes	203682|Planctomycetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
YYD3_k127_1796882_0	441620.Mpop_1224	1.101e-87	304.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,1JQQ0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM Glucose Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
YYD3_k127_1796882_3	1035191.HMPREF0185_02572	4.127e-49	186.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28,Pyr_redox_3
YYD3_k127_1796882_4	1248916.ANFY01000010_gene364	2.255e-31	126.0	COG1708@1|root,COG1708@2|Bacteria,1N1CX@1224|Proteobacteria,2TSWE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
YYD3_k127_180264_1	234267.Acid_6470	2.183e-119	404.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
YYD3_k127_180264_0	986075.CathTA2_0959	6.959e-194	619.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
YYD3_k127_1831239_1	671143.DAMO_1554	7.159e-65	233.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
YYD3_k127_1831239_0	596324.TREVI0001_0899	3.868e-96	331.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YYD3_k127_1832335_7	530564.Psta_1731	1.571e-37	150.0	COG0577@1|root,COG0577@2|Bacteria,2IYHP@203682|Planctomycetes	203682|Planctomycetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1832335_5	225937.HP15_1417	4.605e-54	198.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1S25B@1236|Gammaproteobacteria,466PC@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_1832335_2	1121918.ARWE01000001_gene50	4.408e-110	379.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1Q5XI@1224|Proteobacteria,437EC@68525|delta/epsilon subdivisions,2X2KQ@28221|Deltaproteobacteria,43VY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1832335_6	1121017.AUFG01000020_gene2303	1.433e-49	183.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria,4FHP6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
YYD3_k127_1832335_3	1424334.W822_22580	3.085e-103	359.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
YYD3_k127_1832335_8	266779.Meso_2898	4.154e-08	61.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1832335_1	1268068.PG5_65010	4.207e-146	485.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.5.5,1.1.9.1	ko:K00114,ko:K17760,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_1832335_0	935840.JAEQ01000020_gene2347	1.192e-167	535.0	COG1012@1|root,COG1012@2|Bacteria,1PGZB@1224|Proteobacteria,2V7UC@28211|Alphaproteobacteria,43NAR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YYD3_k127_183990_4	1122604.JONR01000008_gene2284	1.959e-15	78.0	COG0154@1|root,COG0154@2|Bacteria,1NS7J@1224|Proteobacteria,1SMJ8@1236|Gammaproteobacteria,1XA2W@135614|Xanthomonadales	135614|Xanthomonadales	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
YYD3_k127_183990_3	1499967.BAYZ01000080_gene913	1.4e-18	95.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_183990_2	1173025.GEI7407_3359	3.344e-32	134.0	COG1385@1|root,COG1385@2|Bacteria,1G1VG@1117|Cyanobacteria,1HAKC@1150|Oscillatoriales	1117|Cyanobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
YYD3_k127_183990_1	632518.Calow_1327	8.634e-42	165.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,42FBX@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
YYD3_k127_183990_0	1232410.KI421424_gene1723	1.5e-42	160.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD3_k127_1869633_1	1236959.BAMT01000015_gene2849	1.033e-20	96.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1869633_0	234267.Acid_1964	6.262e-134	449.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
YYD3_k127_1869633_2	593750.Metfor_1649	7.587e-11	75.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03042@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAN4@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
YYD3_k127_1869633_3	234267.Acid_1957	4.169e-07	63.0	COG0457@1|root,COG0760@1|root,COG0457@2|Bacteria,COG0760@2|Bacteria,3Y67U@57723|Acidobacteria	57723|Acidobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_1879356_0	1499967.BAYZ01000184_gene4567	2.84e-239	758.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_1879356_1	443143.GM18_1629	2.36e-18	89.0	2EMTG@1|root,33FFU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YYD3_k127_1885707_3	1267533.KB906733_gene3215	1.015e-85	300.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_1885707_1	204669.Acid345_1052	2.95e-199	647.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
YYD3_k127_1885707_0	420662.Mpe_A1450	2.578e-246	775.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VJ7P@28216|Betaproteobacteria,1KJDD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YYD3_k127_1885707_2	420662.Mpe_A1451	4.904e-165	527.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VH8S@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Twin-arginine translocation pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,TAT_signal
YYD3_k127_1885707_4	1121380.JNIW01000061_gene1394	1.64e-32	130.0	COG2521@1|root,COG2521@2|Bacteria	2|Bacteria	AJ	methyltransferase	-	-	2.1.1.113,2.1.1.72	ko:K00590,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methyltransf_11,N6_N4_Mtase
YYD3_k127_1904562_3	234267.Acid_7200	1.87e-92	314.0	COG0820@1|root,COG0820@2|Bacteria,3Y3HQ@57723|Acidobacteria	57723|Acidobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
YYD3_k127_1904562_8	1121918.ARWE01000001_gene1999	7.069e-27	117.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43VC5@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Glutathione peroxidase	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_1904562_6	204669.Acid345_4326	3.268e-67	237.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria,2JI3X@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
YYD3_k127_1904562_0	1382359.JIAL01000001_gene2257	1.147e-179	571.0	COG0015@1|root,COG0015@2|Bacteria,3Y2QW@57723|Acidobacteria,2JIAC@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
YYD3_k127_1904562_2	264732.Moth_0405	1.14e-125	422.0	COG4986@1|root,COG4986@2|Bacteria,1TRRR@1239|Firmicutes,248X4@186801|Clostridia,42HSS@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YYD3_k127_1904562_7	1403819.BATR01000180_gene6025	1.808e-61	220.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YYD3_k127_1904562_10	1123401.JHYQ01000007_gene513	1.111e-20	97.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,460N1@72273|Thiotrichales	72273|Thiotrichales	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
YYD3_k127_1904562_11	379066.GAU_0291	6.889e-16	91.0	29YN3@1|root,30KHK@2|Bacteria,1ZT0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
YYD3_k127_1904562_4	1379270.AUXF01000002_gene1629	1.278e-77	267.0	COG1131@1|root,COG1131@2|Bacteria,1ZT45@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_1904562_12	1406840.Q763_12605	1.109e-11	71.0	COG2862@1|root,COG2862@2|Bacteria,4PNUD@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
YYD3_k127_1904562_1	1123368.AUIS01000024_gene954	3.006e-157	509.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
YYD3_k127_1904562_5	402777.KB235903_gene2324	2.356e-67	234.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1HBZ4@1150|Oscillatoriales	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_1904562_9	319003.Bra1253DRAFT_06341	1.395e-25	119.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria,3JUZ1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_1917522_2	370438.PTH_1585	3.242e-124	414.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,2610T@186807|Peptococcaceae	186801|Clostridia	G	PFAM glycoside hydrolase family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
YYD3_k127_1917522_0	861299.J421_2352	2.303e-140	458.0	COG4102@1|root,COG4102@2|Bacteria,1ZSZ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YYD3_k127_1917522_1	234267.Acid_5563	5.207e-135	447.0	COG5267@1|root,COG5267@2|Bacteria,3Y342@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
YYD3_k127_1917522_5	688245.CtCNB1_4720	1.153e-20	100.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_1917522_3	671143.DAMO_1780	1.913e-34	137.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_1917522_4	1173028.ANKO01000020_gene5455	4.388e-34	135.0	COG0500@1|root,COG2226@2|Bacteria,1G3QN@1117|Cyanobacteria,1H9TM@1150|Oscillatoriales	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD3_k127_1922635_4	1254432.SCE1572_02795	1.426e-52	192.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD3_k127_1922635_2	448385.sce6976	5.84e-108	375.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
YYD3_k127_1922635_5	452637.Oter_3829	2.063e-49	189.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
YYD3_k127_1922635_0	330214.NIDE0029	1.372e-210	675.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
YYD3_k127_1922635_6	1122919.KB905598_gene4380	2.188e-31	136.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,26TAW@186822|Paenibacillaceae	91061|Bacilli	C	Ferredoxin--NADP reductase	trxB5	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
YYD3_k127_1922635_1	1123242.JH636435_gene1110	3.871e-192	608.0	COG1252@1|root,COG1252@2|Bacteria,2IXBA@203682|Planctomycetes	203682|Planctomycetes	C	NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD3_k127_1922635_3	795666.MW7_2722	8.519e-59	213.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,1K0HU@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YYD3_k127_192309_2	404589.Anae109_2540	8.613e-62	228.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2YV41@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD3_k127_192309_0	266117.Rxyl_2540	1.546e-226	719.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
YYD3_k127_192309_3	1274374.CBLK010000053_gene2320	5.221e-22	102.0	COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,26Y43@186822|Paenibacillaceae	91061|Bacilli	O	general stress protein	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
YYD3_k127_192309_1	479434.Sthe_0947	1.766e-152	492.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,27Y49@189775|Thermomicrobia	189775|Thermomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
YYD3_k127_1923261_0	1120970.AUBZ01000061_gene1777	8.997e-76	262.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,469TY@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YYD3_k127_1923261_1	661478.OP10G_2721	5.237e-73	259.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
YYD3_k127_1923261_2	717785.HYPMC_1421	1.325e-26	115.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VF0E@28211|Alphaproteobacteria,3N9CH@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	MA20_44950	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Rhodanese
YYD3_k127_1923261_3	234267.Acid_2629	2.262e-13	76.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_192792_3	234267.Acid_1046	5.946e-140	449.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
YYD3_k127_192792_1	234267.Acid_4577	4.075e-169	548.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_192792_9	234267.Acid_3123	2.202e-28	126.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_192792_0	448385.sce8230	4.036e-301	934.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42ZB0@68525|delta/epsilon subdivisions,2WUQM@28221|Deltaproteobacteria,2Z2YN@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
YYD3_k127_192792_5	396588.Tgr7_1418	7.05e-80	273.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria	1224|Proteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_192792_10	1415780.JPOG01000001_gene3098	0.0006215	44.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria,1XBYT@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the LOG family	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
YYD3_k127_192792_6	398767.Glov_0084	1.163e-49	181.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD3_k127_192792_7	1267533.KB906735_gene5102	3.799e-37	144.0	COG0203@1|root,COG0203@2|Bacteria,3Y4JF@57723|Acidobacteria,2JJ8Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
YYD3_k127_192792_2	1267533.KB906735_gene5103	3.259e-152	488.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
YYD3_k127_192792_4	240015.ACP_1424	7.479e-86	291.0	COG0522@1|root,COG0522@2|Bacteria,3Y2I1@57723|Acidobacteria,2JHR6@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
YYD3_k127_192792_8	234267.Acid_5092	3.329e-36	138.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria	57723|Acidobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
YYD3_k127_1930674_1	880073.Calab_3076	5.306e-14	83.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NNKC@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
YYD3_k127_1938393_5	344747.PM8797T_25126	3.018e-33	136.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_1938393_2	247633.GP2143_18126	6.082e-45	178.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1938393_4	1101195.Meth11DRAFT_1464	3.299e-34	136.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1938393_1	450851.PHZ_c2572	7.591e-75	261.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1938393_6	1340493.JNIF01000003_gene2121	4.513e-30	126.0	2CBAE@1|root,32S20@2|Bacteria,3Y93Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1938393_3	234267.Acid_4489	4.727e-43	167.0	COG0577@1|root,COG0577@2|Bacteria,3Y34I@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1938393_8	234267.Acid_3778	1.563e-14	83.0	COG0577@1|root,COG0577@2|Bacteria,3Y3Z1@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_1938393_0	1267533.KB906741_gene405	6.579e-121	396.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia	204432|Acidobacteriia	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
YYD3_k127_1942152_0	1121422.AUMW01000006_gene774	1.339e-79	278.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,2636Z@186807|Peptococcaceae	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
YYD3_k127_1942152_1	1408424.JHYI01000013_gene1036	1.235e-60	235.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus	91061|Bacilli	L	AAA domain	yhaN	-	-	-	-	-	-	-	-	-	-	-	AAA_27
YYD3_k127_1943936_3	351160.RCIX322	7.833e-42	164.0	COG0428@1|root,arCOG00576@2157|Archaea,2XX28@28890|Euryarchaeota,2NAV5@224756|Methanomicrobia	224756|Methanomicrobia	P	divalent heavy-metal cations transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
YYD3_k127_1943936_1	666685.R2APBS1_1677	3.773e-95	314.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1S228@1236|Gammaproteobacteria,1X4NN@135614|Xanthomonadales	135614|Xanthomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YYD3_k127_1943936_4	1449350.OCH239_11100	2.754e-11	63.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,4KMHN@93682|Roseivivax	28211|Alphaproteobacteria	O	This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YYD3_k127_1943936_2	1385515.N791_12780	2.725e-62	215.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1X771@135614|Xanthomonadales	135614|Xanthomonadales	O	This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YYD3_k127_1943936_5	1047013.AQSP01000109_gene2428	1.03e-08	60.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
YYD3_k127_1943936_0	234267.Acid_5526	1.993e-213	677.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
YYD3_k127_1955502_4	1403819.BATR01000133_gene4726	2.516e-61	229.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,2ITQS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Penicillin-binding Protein dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	PBP_dimer,Transpeptidase
YYD3_k127_1955502_2	1278073.MYSTI_02643	7.143e-121	409.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria,2YUQE@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YYD3_k127_1955502_7	290400.Jann_2086	1.407e-07	60.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	P-type ATPase'	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
YYD3_k127_1955502_6	365044.Pnap_4547	6.388e-09	61.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,4A9KK@80864|Comamonadaceae	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
YYD3_k127_1955502_5	1146883.BLASA_1379	1.521e-21	97.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
YYD3_k127_1955502_0	1380393.JHVP01000004_gene612	1.183e-156	508.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
YYD3_k127_1955502_3	1122604.JONR01000025_gene4602	2.548e-86	308.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
YYD3_k127_1955502_1	118166.JH976537_gene4640	1.596e-126	416.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1G40A@1117|Cyanobacteria,1HI0P@1150|Oscillatoriales	1117|Cyanobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
YYD3_k127_1957429_1	204669.Acid345_2493	3.218e-90	304.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria,2JICI@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YYD3_k127_1957429_3	1358423.N180_15130	3.644e-59	215.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
YYD3_k127_1957429_2	1382359.JIAL01000001_gene2279	3.02e-75	270.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_1957429_5	1267533.KB906739_gene2635	6.565e-17	94.0	COG1965@1|root,COG1965@2|Bacteria,3Y5BU@57723|Acidobacteria,2JJSI@204432|Acidobacteriia	204432|Acidobacteriia	P	Frataxin-like domain	-	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
YYD3_k127_1957429_6	797304.Natgr_3042	2.051e-14	87.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,23TMB@183963|Halobacteria	183963|Halobacteria	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD3_k127_1957429_4	509191.AEDB02000020_gene3360	1.094e-24	110.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24GQ2@186801|Clostridia,3WINH@541000|Ruminococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_1957429_0	1382359.JIAL01000001_gene2012	5.243e-226	717.0	COG1132@1|root,COG1132@2|Bacteria,3Y2XY@57723|Acidobacteria,2JHZ0@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD3_k127_1957429_8	1392498.JQLH01000001_gene2207	2.845e-06	57.0	COG0845@1|root,COG0845@2|Bacteria,4NHFQ@976|Bacteroidetes,1I0Q9@117743|Flavobacteriia,2PIRZ@252356|Maribacter	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
YYD3_k127_1957429_7	765420.OSCT_2186	1.338e-13	74.0	COG3975@1|root,COG3975@2|Bacteria,2GAB7@200795|Chloroflexi,374W2@32061|Chloroflexia	32061|Chloroflexia	S	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
YYD3_k127_1988943_0	234267.Acid_3837	1.334e-40	170.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_1988943_1	1380355.JNIJ01000004_gene2840	2.856e-32	127.0	2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2UBWU@28211|Alphaproteobacteria,3JZF1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3297)	MA20_01105	-	-	-	-	-	-	-	-	-	-	-	DUF3297
YYD3_k127_1988943_2	1120919.AUBI01000011_gene2332	3.097e-32	130.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,2JRV6@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_1994380_1	1267535.KB906767_gene1158	2.971e-137	451.0	COG0044@1|root,COG0044@2|Bacteria,3Y34R@57723|Acidobacteria,2JIA3@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
YYD3_k127_1994380_2	292459.STH1257	1.453e-110	370.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD3_k127_1994380_6	373903.Hore_09350	5.293e-51	186.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WAIW@53433|Halanaerobiales	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
YYD3_k127_1994380_3	1340493.JNIF01000003_gene2948	2.965e-102	341.0	COG0167@1|root,COG0167@2|Bacteria,3Y2K1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
YYD3_k127_1994380_5	338963.Pcar_0684	1.46e-59	215.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,43S93@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
YYD3_k127_1994380_0	1340493.JNIF01000003_gene4390	7.154e-192	609.0	COG2133@1|root,COG2133@2|Bacteria,3Y36R@57723|Acidobacteria	57723|Acidobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_1994380_8	1232410.KI421428_gene1185	2.077e-35	142.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,43UPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YYD3_k127_1994380_9	1340493.JNIF01000003_gene3708	2.665e-09	61.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_1994380_7	1382304.JNIL01000001_gene626	1.007e-41	156.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
YYD3_k127_1994380_4	1267535.KB906767_gene3058	3.684e-83	282.0	COG0336@1|root,COG0336@2|Bacteria,3Y3CS@57723|Acidobacteria,2JHUJ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
YYD3_k127_1994380_10	1382359.JIAL01000001_gene1646	4.337e-05	46.0	COG0806@1|root,COG0806@2|Bacteria,3Y51G@57723|Acidobacteria,2JJGA@204432|Acidobacteriia	204432|Acidobacteriia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
YYD3_k127_2001766_1	986075.CathTA2_1452	6.879e-100	334.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli	91061|Bacilli	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
YYD3_k127_2001766_3	382464.ABSI01000010_gene3415	1.018e-15	87.0	2EEU3@1|root,338MM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2001766_2	189753.AXAS01000019_gene3484	3.102e-17	95.0	COG0457@1|root,COG0457@2|Bacteria,1RCNU@1224|Proteobacteria,2UBHT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TPR_8
YYD3_k127_2001766_0	234267.Acid_0912	1.287e-101	340.0	COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria	57723|Acidobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD3_k127_2003432_0	234267.Acid_1144	1.847e-112	372.0	COG3391@1|root,COG3391@2|Bacteria,3Y98W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_2003432_1	344747.PM8797T_06472	7.011e-101	338.0	29RNN@1|root,30CRY@2|Bacteria	2|Bacteria	-	-	yndG	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
YYD3_k127_2003432_2	1499968.TCA2_4647	3.547e-28	120.0	arCOG11972@1|root,2ZG4P@2|Bacteria,1V2DB@1239|Firmicutes,4HN4N@91061|Bacilli,26UYX@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
YYD3_k127_2012445_6	1189612.A33Q_1484	0.000122	50.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,47QDQ@768503|Cytophagia	976|Bacteroidetes	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_7,TPR_8
YYD3_k127_2012445_5	1340493.JNIF01000004_gene600	6.828e-11	67.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
YYD3_k127_2012445_4	234267.Acid_4171	2.162e-28	126.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2012445_0	661478.OP10G_0721	6.495e-110	365.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD3_k127_2012445_3	398767.Glov_3532	1.535e-36	146.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	DsbA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
YYD3_k127_2012445_1	929558.SMGD1_0182	2.137e-57	206.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
YYD3_k127_2012445_2	627192.SLG_12120	3.528e-41	163.0	2ED7G@1|root,32HXH@2|Bacteria,1NR36@1224|Proteobacteria,2UQ2U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_2019032_2	204669.Acid345_3520	1.715e-96	318.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria,2JI3Z@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD3_k127_2019032_1	1521187.JPIM01000006_gene1717	1.251e-129	422.0	COG4586@1|root,COG4586@2|Bacteria,2G88B@200795|Chloroflexi,376NY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_2019032_4	324602.Caur_0977	1.443e-64	230.0	COG4587@1|root,COG4587@2|Bacteria,2G9N0@200795|Chloroflexi,37604@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
YYD3_k127_2019032_3	324602.Caur_0437	4.149e-69	251.0	COG3694@1|root,COG3694@2|Bacteria,2G90J@200795|Chloroflexi,377JE@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
YYD3_k127_2019032_0	326427.Cagg_2915	1.225e-187	595.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi,376DU@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
YYD3_k127_2019032_6	234267.Acid_1031	6.137e-41	154.0	COG3682@1|root,COG3682@2|Bacteria,3Y8B7@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_2019032_5	234267.Acid_1032	1.748e-45	180.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_C
YYD3_k127_2019412_0	1396418.BATQ01000041_gene6342	5.122e-69	241.0	COG0463@1|root,COG0463@2|Bacteria,46SPS@74201|Verrucomicrobia,2IUQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_2019412_3	439235.Dalk_1372	2.178e-26	125.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MN52@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
YYD3_k127_2019412_6	1121946.AUAX01000020_gene3132	2.141e-08	57.0	COG1680@1|root,COG1680@2|Bacteria,2H8UZ@201174|Actinobacteria,4DBD4@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_2019412_1	278963.ATWD01000003_gene65	1.993e-59	214.0	COG1629@1|root,COG4771@2|Bacteria,3Y8D8@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
YYD3_k127_2019412_8	682795.AciX8_3983	0.0006157	48.0	COG4775@1|root,COG4775@2|Bacteria,3Y2NP@57723|Acidobacteria,2JIUP@204432|Acidobacteriia	204432|Acidobacteriia	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_2019412_2	1283299.AUKG01000004_gene986	1.83e-40	159.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4CTRC@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
YYD3_k127_2019412_5	318424.EU78_27090	1.468e-09	69.0	COG2021@1|root,COG2197@1|root,COG2021@2|Bacteria,COG2197@2|Bacteria,2GN4Z@201174|Actinobacteria,23FBR@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
YYD3_k127_2019412_7	290397.Adeh_2374	5.622e-08	55.0	2ER1F@1|root,33IKZ@2|Bacteria,1PANM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2019565_0	314230.DSM3645_25517	5.906e-140	456.0	COG0415@1|root,COG0415@2|Bacteria,2IXWI@203682|Planctomycetes	203682|Planctomycetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
YYD3_k127_2021354_7	204669.Acid345_4525	1.271e-09	66.0	COG3595@1|root,COG3595@2|Bacteria,3Y8P5@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2021354_0	861299.J421_4207	1.03e-139	477.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_2021354_6	269799.Gmet_1881	2.958e-27	119.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,43V70@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
YYD3_k127_2021354_2	671143.DAMO_1556	1.434e-123	413.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
YYD3_k127_2021354_1	234267.Acid_2719	6.456e-125	411.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD3_k127_2021354_5	1123288.SOV_4c01730	9.346e-38	151.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4H4EZ@909932|Negativicutes	909932|Negativicutes	L	Hydrolase, NUDIX family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
YYD3_k127_2021354_4	1120973.AQXL01000131_gene2058	1.342e-50	195.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,278RA@186823|Alicyclobacillaceae	91061|Bacilli	EGP	MFS_1 like family	-	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,MFS_1_like,Sugar_tr
YYD3_k127_2021354_8	91464.S7335_4211	2.383e-06	59.0	COG0715@1|root,COG0715@2|Bacteria,1G0PU@1117|Cyanobacteria,1GZ3S@1129|Synechococcus	1117|Cyanobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
YYD3_k127_2021354_3	627192.SLG_07720	1.139e-112	374.0	COG3384@1|root,COG3384@2|Bacteria,1R6R4@1224|Proteobacteria,2U82Q@28211|Alphaproteobacteria,2K4FE@204457|Sphingomonadales	204457|Sphingomonadales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15061,ko:K15065	ko00627,ko01120,map00627,map01120	-	R09272,R09276	RC01306,RC01369	ko00000,ko00001,ko01000	-	-	-	LigB
YYD3_k127_2026226_7	935567.JAES01000023_gene2520	4.207e-59	214.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3JU@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrF	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD3_k127_2026226_12	502025.Hoch_3262	4.96e-31	131.0	COG1721@1|root,COG1721@2|Bacteria,1NEAC@1224|Proteobacteria,43B78@68525|delta/epsilon subdivisions,2X6KP@28221|Deltaproteobacteria,2YWA8@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YYD3_k127_2026226_1	309799.DICTH_1964	9.879e-120	396.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD3_k127_2026226_15	497964.CfE428DRAFT_1404	0.0002108	54.0	COG0497@1|root,COG0497@2|Bacteria	2|Bacteria	L	DNA recombination	recN	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03631,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
YYD3_k127_2026226_8	861299.J421_1974	2.649e-53	214.0	COG3595@1|root,COG4219@1|root,COG3595@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	DUF4097
YYD3_k127_2026226_10	886293.Sinac_6279	2.757e-49	178.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_2026226_0	1121468.AUBR01000026_gene2920	1.492e-136	445.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
YYD3_k127_2026226_9	748224.HMPREF9436_02258	2.4e-50	185.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
YYD3_k127_2026226_6	697281.Mahau_1521	5.866e-75	265.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
YYD3_k127_2026226_2	204669.Acid345_3336	1.004e-116	383.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
YYD3_k127_2026226_5	234267.Acid_0313	6.558e-93	319.0	COG0240@1|root,COG0240@2|Bacteria,3Y3ZH@57723|Acidobacteria	57723|Acidobacteria	C	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YYD3_k127_2026226_11	234267.Acid_0315	9.41e-34	136.0	COG1514@1|root,COG1514@2|Bacteria,3Y5S7@57723|Acidobacteria	57723|Acidobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
YYD3_k127_2026226_3	1047013.AQSP01000094_gene29	5.698e-103	349.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
YYD3_k127_2026226_4	1267535.KB906767_gene1016	6.11e-102	342.0	COG3391@1|root,COG3391@2|Bacteria,3Y99Z@57723|Acidobacteria,2JP6W@204432|Acidobacteriia	204432|Acidobacteriia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2026226_13	290512.Paes_1687	4.183e-30	126.0	COG1267@1|root,COG1267@2|Bacteria,1FE6P@1090|Chlorobi	1090|Chlorobi	I	PFAM phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
YYD3_k127_2026226_14	1479237.JMLY01000001_gene3006	7.684e-14	73.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,468WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
YYD3_k127_2036013_9	715451.ambt_12010	0.0003379	51.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2036013_6	871963.Desdi_2794	9.512e-72	249.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_2036013_4	290397.Adeh_4006	9.604e-80	274.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
YYD3_k127_2036013_2	290397.Adeh_4005	2.695e-95	321.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD3_k127_2036013_1	1131812.JQMS01000001_gene1240	1.579e-99	334.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia,2NSWN@237|Flavobacterium	976|Bacteroidetes	P	permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
YYD3_k127_2036013_0	983920.Y88_0966	5.717e-106	349.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JZZN@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
YYD3_k127_2036013_8	443143.GM18_1519	4.898e-69	241.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria,43TYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
YYD3_k127_2036013_7	335543.Sfum_2892	7.247e-71	247.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	phoB	-	-	ko:K07657,ko:K07664	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_2036013_5	443143.GM18_1524	2.293e-76	273.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
YYD3_k127_2036013_3	1183438.GKIL_4343	8.979e-86	302.0	COG0248@1|root,COG0248@2|Bacteria,1FZZC@1117|Cyanobacteria	1117|Cyanobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
YYD3_k127_204494_6	1267535.KB906767_gene3529	2.689e-40	151.0	COG1695@1|root,COG1695@2|Bacteria,3Y80F@57723|Acidobacteria,2JMYK@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_204494_0	1267535.KB906767_gene3131	2.254e-181	599.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria,2JI3C@204432|Acidobacteriia	204432|Acidobacteriia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_204494_4	1380393.JHVP01000004_gene680	9.067e-72	246.0	COG3631@1|root,COG3631@2|Bacteria,2II8E@201174|Actinobacteria,4EVCD@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
YYD3_k127_204494_7	1267535.KB906767_gene2973	2.274e-24	107.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_204494_2	1210884.HG799472_gene14911	1.88e-108	364.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_204494_1	1123242.JH636435_gene2922	6.622e-134	441.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_204494_3	330214.NIDE3611	3.938e-98	336.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
YYD3_k127_204494_5	204669.Acid345_0496	1.865e-69	244.0	COG3568@1|root,COG3568@2|Bacteria,3Y4HM@57723|Acidobacteria,2JKST@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
YYD3_k127_204494_8	1216976.AX27061_4206	5.793e-20	91.0	COG2323@1|root,COG2323@2|Bacteria,1RATW@1224|Proteobacteria,2VTFY@28216|Betaproteobacteria,3T3ZU@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
YYD3_k127_2056118_1	478741.JAFS01000002_gene105	1.953e-109	360.0	COG1222@1|root,COG1222@2|Bacteria,46UBC@74201|Verrucomicrobia,37GE5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Proteasomal ATPase OB/ID domain	-	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
YYD3_k127_2056118_0	478741.JAFS01000002_gene104	3.606e-152	494.0	COG4122@1|root,COG4122@2|Bacteria,46TEU@74201|Verrucomicrobia,37G25@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Pup-ligase protein	-	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
YYD3_k127_20747_2	1499968.TCA2_4647	3.073e-80	272.0	arCOG11972@1|root,2ZG4P@2|Bacteria,1V2DB@1239|Firmicutes,4HN4N@91061|Bacilli,26UYX@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
YYD3_k127_20747_3	886293.Sinac_1155	6.19e-79	284.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
YYD3_k127_20747_1	234267.Acid_2032	5.745e-130	428.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_20747_0	234267.Acid_5827	2.279e-241	769.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_20747_4	1340493.JNIF01000003_gene4631	3.812e-65	232.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
YYD3_k127_20747_5	1205680.CAKO01000042_gene5322	3.802e-15	76.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	decarboxylase	MA20_22785	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
YYD3_k127_2101116_0	314230.DSM3645_17550	3.781e-204	656.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YYD3_k127_2101116_1	1521187.JPIM01000065_gene1265	1.227e-92	324.0	COG0457@1|root,COG0457@2|Bacteria	1521187.JPIM01000065_gene1265|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2101116_2	234267.Acid_5123	3.736e-32	126.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria	57723|Acidobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YYD3_k127_2102293_2	134676.ACPL_2188	4.905e-131	425.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YYD3_k127_2102293_3	134676.ACPL_2189	5.586e-112	368.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4DE6Q@85008|Micromonosporales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
YYD3_k127_2102293_0	134676.ACPL_2190	4.5e-321	996.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4DAPT@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
YYD3_k127_2102293_1	134676.ACPL_2191	1.825e-188	604.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4DG36@85008|Micromonosporales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_2103171_1	234267.Acid_3607	1.337e-44	163.0	COG1695@1|root,COG1695@2|Bacteria,3Y89H@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_2103171_0	234267.Acid_5601	5.729e-155	524.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2103171_2	1267533.KB906736_gene1366	8.003e-22	100.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD3_k127_2107284_3	1382303.JPOM01000001_gene1745	3.453e-26	114.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2KF9M@204458|Caulobacterales	204458|Caulobacterales	CG	PQQ-like domain	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ
YYD3_k127_2107284_2	298654.FraEuI1c_2167	7.722e-71	246.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4EWG8@85013|Frankiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
YYD3_k127_2107284_1	1123277.KB893244_gene5040	7.763e-105	352.0	COG1680@1|root,COG1680@2|Bacteria,4NP4H@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_2107284_0	1040989.AWZU01000105_gene134	2.501e-139	460.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,3JU44@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2107284_4	627192.SLG_12120	2.863e-08	58.0	2ED7G@1|root,32HXH@2|Bacteria,1NR36@1224|Proteobacteria,2UQ2U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_2124201_0	448385.sce4091	7.682e-74	259.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria	1224|Proteobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_4,Protoglobin,STAS
YYD3_k127_2124201_3	645465.ACUR01000602_gene843	1.491e-30	124.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_2124201_1	1121127.JAFA01000002_gene1762	2.728e-32	130.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,2VSW8@28216|Betaproteobacteria,1K88Q@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
YYD3_k127_2124201_2	1247963.JPHU01000010_gene2266	1.123e-31	138.0	COG2172@1|root,COG2172@2|Bacteria,1RD6C@1224|Proteobacteria,2U5V8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
YYD3_k127_2128723_4	749414.SBI_06393	1.032e-06	53.0	COG2319@1|root,COG3267@1|root,COG2319@2|Bacteria,COG3267@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,HTH_3,HTH_31,WD40
YYD3_k127_2128723_2	247490.KSU1_B0100	6.337e-155	499.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YYD3_k127_2128723_3	1005048.CFU_3523	8.657e-16	86.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VSR3@28216|Betaproteobacteria,4757F@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_2128723_1	1304885.AUEY01000096_gene2839	1.294e-179	581.0	COG1404@1|root,COG2304@1|root,COG2911@1|root,COG3897@1|root,COG5434@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3897@2|Bacteria,COG5434@2|Bacteria,1P8N9@1224|Proteobacteria,43DXZ@68525|delta/epsilon subdivisions,2X72D@28221|Deltaproteobacteria,2MNHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
YYD3_k127_2128723_0	1123508.JH636443_gene5010	4.18e-187	623.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
YYD3_k127_2128723_5	1499967.BAYZ01000080_gene938	5.36e-06	54.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
YYD3_k127_2131218_0	886293.Sinac_2692	2.252e-130	425.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IZS3@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
YYD3_k127_2131218_2	517722.AEUE01000010_gene626	4.804e-20	98.0	2C6BD@1|root,2ZZIY@2|Bacteria,1NWJY@1224|Proteobacteria,2USK5@28211|Alphaproteobacteria,2KAE8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2131218_1	1267533.KB906739_gene2641	2.722e-63	219.0	COG0667@1|root,COG0667@2|Bacteria,3Y35T@57723|Acidobacteria	57723|Acidobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD3_k127_2177953_0	234267.Acid_5120	8.61e-225	700.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria	57723|Acidobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD3_k127_2177953_6	204669.Acid345_1225	3.028e-51	183.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
YYD3_k127_2177953_3	1121920.AUAU01000010_gene103	4.542e-79	269.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
YYD3_k127_2177953_5	234267.Acid_5117	5.906e-64	226.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
YYD3_k127_2177953_9	1382359.JIAL01000001_gene1698	1.264e-26	114.0	COG0089@1|root,COG0089@2|Bacteria,3Y58W@57723|Acidobacteria,2JJR2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
YYD3_k127_2177953_1	278963.ATWD01000001_gene1837	3.099e-126	409.0	COG0090@1|root,COG0090@2|Bacteria,3Y3DH@57723|Acidobacteria,2JI2K@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
YYD3_k127_2177953_7	240015.ACP_1447	1.638e-38	146.0	COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria,2JJMI@204432|Acidobacteriia	204432|Acidobacteriia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
YYD3_k127_2177953_8	234267.Acid_5113	3.731e-37	145.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria	57723|Acidobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
YYD3_k127_2177953_2	1267535.KB906767_gene2698	1.577e-108	356.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria,2JIRU@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
YYD3_k127_2177953_4	240015.ACP_1444	5.128e-68	234.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria,2JJ2G@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
YYD3_k127_218494_1	225117.XP_009342961.1	6.016e-08	57.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37NJY@33090|Viridiplantae,3G7EB@35493|Streptophyta,4JIQ1@91835|fabids	35493|Streptophyta	A	29 kDa ribonucleoprotein	-	GO:0001101,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008187,GO:0008266,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009631,GO:0009719,GO:0009725,GO:0009737,GO:0009892,GO:0009894,GO:0009895,GO:0009941,GO:0010033,GO:0010319,GO:0010468,GO:0010605,GO:0010608,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0033993,GO:0034357,GO:0042221,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043487,GO:0043489,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0055035,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:0097305,GO:1901363,GO:1901700,GO:1902369	-	ko:K11294	ko05130,map05130	-	-	-	ko00000,ko00001,ko03009,ko03036	-	-	-	RRM_1
YYD3_k127_218494_0	84588.SYNW2353	1.701e-87	302.0	COG1364@1|root,COG1364@2|Bacteria,1G1H7@1117|Cyanobacteria,1GZ07@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argJ	ArgJ
YYD3_k127_2190344_12	1227276.HMPREF9148_02755	5.936e-05	47.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YYD3_k127_2190344_8	470.IX87_15180	3.683e-15	88.0	COG3103@1|root,COG3103@2|Bacteria,1QU7Q@1224|Proteobacteria,1T1Q2@1236|Gammaproteobacteria,3NMBG@468|Moraxellaceae	1236|Gammaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2190344_2	1122604.JONR01000045_gene2483	6.98e-146	479.0	2DBEC@1|root,2Z8RY@2|Bacteria,1MXRI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
YYD3_k127_2190344_13	195250.CM001776_gene1450	0.0003691	48.0	COG5512@1|root,COG5512@2|Bacteria,1G87Q@1117|Cyanobacteria,1H1WD@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
YYD3_k127_2190344_10	103690.17132287	5.22e-09	61.0	COG0721@1|root,COG0721@2|Bacteria,1G7N8@1117|Cyanobacteria,1HP1J@1161|Nostocales	1117|Cyanobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
YYD3_k127_2190344_1	246194.CHY_1102	4.552e-181	582.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_2190344_11	278963.ATWD01000001_gene3853	5.568e-09	66.0	COG2825@1|root,COG2825@2|Bacteria,3Y4WC@57723|Acidobacteria,2JJHF@204432|Acidobacteriia	204432|Acidobacteriia	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
YYD3_k127_2190344_0	246194.CHY_1103	1.845e-183	586.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
YYD3_k127_2190344_3	639030.JHVA01000001_gene1180	4.828e-125	409.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
YYD3_k127_2190344_4	1267535.KB906767_gene399	6.856e-102	344.0	COG0533@1|root,COG0533@2|Bacteria,3Y2PN@57723|Acidobacteria,2JHJ0@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YYD3_k127_2190344_5	639030.JHVA01000001_gene397	1.225e-46	193.0	COG1629@1|root,COG4771@2|Bacteria,3Y461@57723|Acidobacteria,2JHPM@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_2190344_7	1210884.HG799468_gene13554	7.249e-36	140.0	COG1725@1|root,COG1725@2|Bacteria,2J03Y@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
YYD3_k127_2190344_6	661478.OP10G_2516	8.231e-44	166.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_2191186_1	760568.Desku_3099	7.671e-44	162.0	COG5550@1|root,COG5550@2|Bacteria,1W58U@1239|Firmicutes,255IM@186801|Clostridia	186801|Clostridia	O	TIGRFAM clan AA aspartic protease, AF_0612 family	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2191186_0	1382359.JIAL01000001_gene1138	2.744e-141	455.0	COG0606@1|root,COG0606@2|Bacteria,3Y3JA@57723|Acidobacteria,2JI3F@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
YYD3_k127_2193524_0	1267535.KB906767_gene1738	1.684e-95	337.0	COG3829@1|root,COG3829@2|Bacteria,3Y6K2@57723|Acidobacteria	57723|Acidobacteria	KT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
YYD3_k127_2193524_1	1499967.BAYZ01000194_gene3127	1.082e-70	246.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YYD3_k127_2193524_2	264201.pc0979	4.6e-52	187.0	COG2346@1|root,COG2346@2|Bacteria,2JH1G@204428|Chlamydiae	204428|Chlamydiae	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
YYD3_k127_2193524_3	1123242.JH636435_gene2797	4.871e-28	116.0	COG2010@1|root,COG2010@2|Bacteria,2J547@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2227484_0	1128421.JAGA01000002_gene335	6.084e-152	495.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
YYD3_k127_2227484_2	517417.Cpar_0972	3.702e-42	162.0	COG0847@1|root,COG0847@2|Bacteria,1FDW7@1090|Chlorobi	1090|Chlorobi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
YYD3_k127_2238179_2	290512.Paes_2385	5.31e-52	199.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
YYD3_k127_2238179_0	1112216.JH594425_gene574	4.214e-168	537.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
YYD3_k127_2238179_4	1297865.APJD01000011_gene6600	2.304e-33	141.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,3JUHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2238179_1	1123248.KB893325_gene1223	1.966e-74	273.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NIKG@976|Bacteroidetes,1IWUH@117747|Sphingobacteriia	976|Bacteroidetes	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
YYD3_k127_2238179_3	1121920.AUAU01000004_gene742	5.179e-48	177.0	COG3832@1|root,COG3832@2|Bacteria,3Y57B@57723|Acidobacteria	57723|Acidobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
YYD3_k127_2238179_5	1396858.Q666_16435	6.383e-12	68.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,4656T@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG2217 Cation transport ATPase	copA1	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
YYD3_k127_2238179_6	604331.AUHY01000009_gene408	1.13e-11	68.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YYD3_k127_2241211_1	398525.KB900701_gene7124	3.173e-159	516.0	COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,3JT8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_2241211_2	1121861.KB899930_gene196	1.035e-122	400.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSF3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YYD3_k127_2241211_3	1382356.JQMP01000004_gene272	5.854e-113	371.0	COG1173@1|root,COG1173@2|Bacteria,2G63I@200795|Chloroflexi,27XQD@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
YYD3_k127_2241211_0	518766.Rmar_0629	2.105e-162	540.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
YYD3_k127_2263857_3	204669.Acid345_2362	1.217e-24	109.0	COG0454@1|root,COG0456@2|Bacteria,3Y5KS@57723|Acidobacteria,2JJY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
YYD3_k127_2263857_2	671143.DAMO_1553	8.373e-28	121.0	COG1214@1|root,COG1214@2|Bacteria,2NPK8@2323|unclassified Bacteria	2|Bacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
YYD3_k127_2263857_0	1123508.JH636439_gene1333	2.004e-110	370.0	COG0577@1|root,COG0577@2|Bacteria,2IY2P@203682|Planctomycetes	203682|Planctomycetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX,MacB_PCD
YYD3_k127_2263857_1	1444309.JAQG01000157_gene3244	3.701e-86	292.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,26R6I@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_2263857_4	1379270.AUXF01000001_gene1949	2.042e-06	53.0	COG0845@1|root,COG0845@2|Bacteria,1ZU07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YYD3_k127_2268546_1	1487953.JMKF01000006_gene5838	5.506e-17	85.0	COG0671@1|root,COG0671@2|Bacteria,1GHH3@1117|Cyanobacteria,1HI2U@1150|Oscillatoriales	1117|Cyanobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PAP2
YYD3_k127_2268546_0	886293.Sinac_6023	1.982e-162	553.0	COG2239@1|root,COG2239@2|Bacteria,2IX38@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
YYD3_k127_2268546_3	880072.Desac_0413	2.58e-05	55.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,42S2Q@68525|delta/epsilon subdivisions,2WNSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD3_k127_2296932_6	234267.Acid_3643	1.691e-105	357.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	LpoB,Sel1
YYD3_k127_2296932_1	234267.Acid_7271	4.433e-245	779.0	COG0421@1|root,COG0421@2|Bacteria,3Y6UP@57723|Acidobacteria	57723|Acidobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YYD3_k127_2296932_9	450851.PHZ_c3077	4.708e-27	124.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2296932_8	247633.GP2143_17801	1.764e-38	150.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2296932_7	247633.GP2143_18121	4.925e-80	277.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2296932_3	404589.Anae109_0505	4.286e-114	375.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
YYD3_k127_2296932_0	29581.BW37_00307	6.116e-266	849.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_2296932_4	240015.ACP_0343	5.99e-109	362.0	COG0812@1|root,COG0812@2|Bacteria,3Y3AT@57723|Acidobacteria,2JIMJ@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
YYD3_k127_2296932_5	278963.ATWD01000001_gene3517	1.373e-107	359.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
YYD3_k127_2296932_2	1123277.KB893244_gene5020	1.483e-195	627.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
YYD3_k127_2306305_0	204669.Acid345_0718	1.224e-42	165.0	COG0072@1|root,COG0072@2|Bacteria,3Y353@57723|Acidobacteria,2JIM2@204432|Acidobacteriia	204432|Acidobacteriia	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB
YYD3_k127_2306305_2	1382359.JIAL01000001_gene1198	7.835e-06	51.0	2ESG3@1|root,33K0W@2|Bacteria,3Y5YI@57723|Acidobacteria,2JK4B@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2306305_1	330214.NIDE3725	7.741e-08	57.0	COG3027@1|root,COG3027@2|Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
YYD3_k127_2327286_6	498761.HM1_3148	4.184e-25	106.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2327286_5	221288.JH992901_gene4347	2.963e-30	123.0	2DPM9@1|root,332MQ@2|Bacteria,1GAJY@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2327286_8	935837.JAEK01000039_gene3871	5.925e-14	72.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes,4IMUS@91061|Bacilli,1ZKVY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2327286_1	1382359.JIAL01000001_gene2058	7.858e-109	367.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD3_k127_2327286_7	289376.THEYE_A0045	2.326e-23	108.0	COG4856@1|root,COG4856@2|Bacteria,3J1EE@40117|Nitrospirae	40117|Nitrospirae	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
YYD3_k127_2327286_3	204669.Acid345_0278	1.594e-71	250.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
YYD3_k127_2327286_2	316067.Geob_3422	6.061e-73	255.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
YYD3_k127_2327286_0	1382359.JIAL01000001_gene416	1.715e-269	843.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YYD3_k127_2327286_4	1347392.CCEZ01000020_gene947	7.382e-61	227.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,36EWX@31979|Clostridiaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YYD3_k127_2331715_3	240015.ACP_2960	1.972e-52	191.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria,2JJ48@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
YYD3_k127_2331715_4	8049.ENSGMOP00000019184	1.473e-09	67.0	COG3177@1|root,KOG3824@2759|Eukaryota,38B91@33154|Opisthokonta,3BDIM@33208|Metazoa,3CV6D@33213|Bilateria,483DR@7711|Chordata,498T7@7742|Vertebrata,49RKA@7898|Actinopterygii	33208|Metazoa	S	FIC domain containing	FICD	GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897	-	-	-	-	-	-	-	-	-	-	Fic
YYD3_k127_2331715_2	1210884.HG799465_gene11770	7.558e-100	336.0	COG0476@1|root,COG0476@2|Bacteria,2IWVB@203682|Planctomycetes	203682|Planctomycetes	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
YYD3_k127_2331715_0	368407.Memar_2038	8.997e-233	738.0	COG0388@1|root,arCOG00062@2157|Archaea,2XVVK@28890|Euryarchaeota,2NBG5@224756|Methanomicrobia	224756|Methanomicrobia	S	Porphyromonas-type peptidyl-arginine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase,PAD_porph
YYD3_k127_2331715_1	518766.Rmar_1413	8.138e-101	337.0	COG1166@1|root,COG1166@2|Bacteria,4PKX0@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YYD3_k127_2333483_0	765869.BDW_11325	2.212e-55	213.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2MT1A@213481|Bdellovibrionales,2WNNV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD3_k127_2333483_2	1382359.JIAL01000001_gene1085	1.86e-05	52.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_233781_3	1267535.KB906767_gene2540	7.011e-40	151.0	COG1208@1|root,COG1208@2|Bacteria,3Y4HJ@57723|Acidobacteria,2JMPU@204432|Acidobacteriia	204432|Acidobacteriia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
YYD3_k127_233781_0	671143.DAMO_0940	8.218e-82	286.0	COG0279@1|root,COG0279@2|Bacteria,2NQPQ@2323|unclassified Bacteria	2|Bacteria	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
YYD3_k127_233781_2	1267535.KB906767_gene2538	7.513e-54	204.0	COG0241@1|root,COG0241@2|Bacteria,3Y7VH@57723|Acidobacteria	57723|Acidobacteria	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
YYD3_k127_233781_1	671143.DAMO_0942	7.168e-71	244.0	COG0176@1|root,COG0176@2|Bacteria,2NP61@2323|unclassified Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YYD3_k127_2343789_3	1382359.JIAL01000001_gene139	2.423e-29	125.0	COG5373@1|root,COG5373@2|Bacteria,3Y2GV@57723|Acidobacteria,2JIMY@204432|Acidobacteriia	204432|Acidobacteriia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
YYD3_k127_2343789_4	1123234.AUKI01000011_gene1050	2.17e-05	57.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
YYD3_k127_2343789_1	97096.XP_007790920.1	1.843e-91	320.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_2343789_2	237368.SCABRO_03982	1.388e-48	185.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YYD3_k127_2343789_0	530564.Psta_0958	9.198e-130	417.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
YYD3_k127_2369219_0	880073.Calab_3149	2.493e-107	361.0	COG0301@1|root,COG0301@2|Bacteria,2NPBT@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
YYD3_k127_2369219_3	338963.Pcar_1691	1.611e-52	192.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
YYD3_k127_2369219_5	404589.Anae109_2451	1.631e-40	163.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,2YVD8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
YYD3_k127_2369219_6	234267.Acid_0132	4.252e-26	111.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria	57723|Acidobacteria	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
YYD3_k127_2369219_2	1410620.SHLA_85c000180	2.329e-69	246.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,4B889@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
YYD3_k127_2369219_4	1121441.AUCX01000009_gene2470	2.162e-41	161.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2X5PR@28221|Deltaproteobacteria,2MBC8@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
YYD3_k127_2369219_1	1382359.JIAL01000001_gene2620	2.763e-81	284.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria,2JI1B@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
YYD3_k127_2379709_2	1379698.RBG1_1C00001G0780	2.372e-14	74.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
YYD3_k127_2379709_1	671143.DAMO_0822	1.396e-117	392.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
YYD3_k127_2379709_0	880073.Calab_1598	5.819e-135	453.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
YYD3_k127_2388647_0	572546.Arcpr_0590	1.85e-68	256.0	COG0383@1|root,arCOG03661@2157|Archaea,2XVNX@28890|Euryarchaeota	28890|Euryarchaeota	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
YYD3_k127_2388678_0	1267535.KB906767_gene1458	6.695e-114	378.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
YYD3_k127_2388678_2	234267.Acid_5253	7.184e-58	207.0	COG0546@1|root,COG0546@2|Bacteria,3Y4RC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
YYD3_k127_2388678_1	1382359.JIAL01000001_gene2223	2.39e-73	257.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	204432|Acidobacteriia	Q	pfam abc	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD3_k127_2411060_0	1267535.KB906767_gene1129	1.869e-74	260.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_2411060_6	768671.ThimaDRAFT_4485	6.208e-10	71.0	COG0265@1|root,COG1075@1|root,COG2304@1|root,COG0265@2|Bacteria,COG1075@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	MA20_07505	-	1.1.3.6,1.6.5.3,3.4.21.107	ko:K00337,ko:K03333,ko:K04771,ko:K07114	ko00190,ko00984,ko01100,ko01120,ko01503,ko02020,map00190,map00984,map01100,map01120,map01503,map02020	M00144,M00728	R01459,R11945	RC00061,RC00146	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.A.13.2.2,1.A.13.2.3,3.D.1	-	-	DUF1194
YYD3_k127_2411060_5	234267.Acid_5036	1.352e-21	109.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cya3	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
YYD3_k127_2411060_1	1499967.BAYZ01000090_gene4936	1.349e-46	186.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YYD3_k127_2411060_3	1192034.CAP_4685	5.034e-34	140.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD3_k127_2411060_7	75379.Tint_1949	4.279e-05	51.0	COG4994@1|root,COG4994@2|Bacteria,1N9R8@1224|Proteobacteria,2VXRK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YYD3_k127_2411060_2	1267535.KB906767_gene1870	5.058e-43	162.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
YYD3_k127_2411060_4	1501230.ET33_03090	2.053e-33	132.0	COG2259@1|root,31BQE@2|Bacteria,1VXQN@1239|Firmicutes,4HXCN@91061|Bacilli,26YSK@186822|Paenibacillaceae	91061|Bacilli	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
YYD3_k127_2417154_0	234267.Acid_7271	3.712e-214	684.0	COG0421@1|root,COG0421@2|Bacteria,3Y6UP@57723|Acidobacteria	57723|Acidobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YYD3_k127_2417154_2	1340493.JNIF01000003_gene4251	6.512e-20	102.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
YYD3_k127_2417154_1	234267.Acid_2629	6.683e-27	127.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_2422475_1	234267.Acid_3223	6.155e-34	143.0	28ZVZ@1|root,2ZMKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2422475_3	1313421.JHBV01000003_gene595	8.979e-06	58.0	COG2067@1|root,COG2067@2|Bacteria,4NRUP@976|Bacteroidetes	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2422475_2	5145.XP_001912160.1	6.92e-10	67.0	2EBD3@1|root,2SHGJ@2759|Eukaryota,39TQZ@33154|Opisthokonta,3NZP0@4751|Fungi,3QR77@4890|Ascomycota,218S5@147550|Sordariomycetes,3UABU@5139|Sordariales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2422475_0	1126627.BAWE01000005_gene6111	4.392e-55	223.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG4070@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4070@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin-like,Calx-beta,DUF4347,He_PIG
YYD3_k127_242708_1	448385.sce3921	0.0	1094.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
YYD3_k127_242708_5	682795.AciX8_2680	3.362e-52	188.0	28NYH@1|root,2ZBVN@2|Bacteria,3Y4AN@57723|Acidobacteria,2JJ51@204432|Acidobacteriia	204432|Acidobacteriia	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
YYD3_k127_242708_4	234267.Acid_7537	1.58e-64	228.0	COG2717@1|root,COG2717@2|Bacteria,3Y58Y@57723|Acidobacteria	57723|Acidobacteria	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
YYD3_k127_242708_2	518766.Rmar_0538	1.026e-111	371.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
YYD3_k127_242708_0	1207063.P24_15514	0.0	1167.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2JQQN@204441|Rhodospirillales	204441|Rhodospirillales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
YYD3_k127_242708_3	1123392.AQWL01000002_gene1991	5.607e-65	228.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,1KSVB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
YYD3_k127_2433911_2	216591.BCAM2432	4.873e-39	149.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,1K003@119060|Burkholderiaceae	28216|Betaproteobacteria	I	carboxylase	accB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
YYD3_k127_2433911_1	525904.Tter_1673	3.418e-54	196.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
YYD3_k127_2433911_0	1267533.KB906739_gene2638	1.034e-234	741.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
YYD3_k127_2433911_3	555793.WSK_4046	2.19e-21	98.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2437892_2	469383.Cwoe_5473	8.259e-22	100.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_2437892_1	1380394.JADL01000001_gene2730	8.336e-130	424.0	COG0451@1|root,COG0451@2|Bacteria,1R4Q0@1224|Proteobacteria,2URM5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
YYD3_k127_2437892_3	1034943.BN1094_02799	4.502e-17	87.0	COG2227@1|root,COG2227@2|Bacteria,1QC3V@1224|Proteobacteria,1T7S8@1236|Gammaproteobacteria,1JFS3@118969|Legionellales	118969|Legionellales	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
YYD3_k127_2437892_0	469383.Cwoe_5467	6.044e-159	511.0	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4CQEY@84995|Rubrobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_2437892_4	187303.BN69_2078	2.684e-14	73.0	COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
YYD3_k127_2453715_0	204669.Acid345_4522	1.324e-152	501.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria,2JHRS@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YYD3_k127_2453715_1	1382359.JIAL01000001_gene2101	1.557e-145	469.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YYD3_k127_2453715_4	682795.AciX8_2149	2.119e-29	132.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y2VC@57723|Acidobacteria,2JHR2@204432|Acidobacteriia	204432|Acidobacteriia	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
YYD3_k127_2453715_2	204669.Acid345_1265	4.259e-106	362.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria,2JJTZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_2453715_3	234267.Acid_3837	1.363e-39	162.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_2454122_1	1123228.AUIH01000003_gene964	2.497e-16	79.0	COG3324@1|root,COG3324@2|Bacteria,1PY56@1224|Proteobacteria,1TKNM@1236|Gammaproteobacteria,1XMWH@135619|Oceanospirillales	135619|Oceanospirillales	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_2454122_0	926549.KI421517_gene768	6.849e-144	464.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,47K0T@768503|Cytophagia	976|Bacteroidetes	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_2454122_2	469383.Cwoe_5869	4.177e-16	84.0	COG3662@1|root,COG3662@2|Bacteria,2II6C@201174|Actinobacteria,4CREG@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
YYD3_k127_2462869_3	627192.SLG_31390	6.549e-85	298.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_2462869_1	479434.Sthe_1507	6.732e-121	402.0	COG0477@1|root,COG2814@2|Bacteria,2G8DX@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_2462869_0	1267534.KB906754_gene3665	1.634e-193	621.0	COG0154@1|root,COG0154@2|Bacteria,3Y3IP@57723|Acidobacteria,2JKVH@204432|Acidobacteriia	204432|Acidobacteriia	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_2462869_2	234267.Acid_1761	2.741e-110	370.0	COG1355@1|root,COG1355@2|Bacteria,3Y5Z0@57723|Acidobacteria	57723|Acidobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
YYD3_k127_2462869_4	357808.RoseRS_4404	5.047e-05	47.0	COG1082@1|root,COG1082@2|Bacteria,2G87S@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_2463719_4	204669.Acid345_3286	3.562e-42	162.0	COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria,2JJM3@204432|Acidobacteriia	204432|Acidobacteriia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
YYD3_k127_2463719_0	1267534.KB906756_gene25	5.506e-186	591.0	COG0439@1|root,COG0439@2|Bacteria,3Y2QZ@57723|Acidobacteria,2JIFS@204432|Acidobacteriia	204432|Acidobacteriia	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD3_k127_2463719_5	1121430.JMLG01000003_gene572	2.019e-34	138.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,260JY@186807|Peptococcaceae	186801|Clostridia	CI	Acetyl-CoA carboxylase, biotin carboxyl carrier protein	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
YYD3_k127_2463719_3	204669.Acid345_1473	6.071e-79	290.0	COG4796@1|root,COG4796@2|Bacteria,3Y98D@57723|Acidobacteria	57723|Acidobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
YYD3_k127_2463719_9	1298593.TOL_3240	2.362e-13	78.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1XJVN@135619|Oceanospirillales	135619|Oceanospirillales	NU	Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
YYD3_k127_2463719_8	204669.Acid345_1470	7.289e-14	79.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
YYD3_k127_2463719_2	204669.Acid345_1469	1.306e-99	338.0	COG4972@1|root,COG4972@2|Bacteria,3Y804@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YYD3_k127_2463719_6	204669.Acid345_1468	1.599e-18	87.0	COG3311@1|root,COG3311@2|Bacteria,3Y5MJ@57723|Acidobacteria,2JJZN@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
YYD3_k127_2463719_1	1382359.JIAL01000001_gene2930	3.625e-139	461.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria,2JHJ5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD3_k127_2463719_7	234267.Acid_3425	2.375e-16	92.0	COG4932@1|root,COG4932@2|Bacteria,3Y7YN@57723|Acidobacteria	57723|Acidobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_2486509_2	1158182.KB905021_gene753	1.162e-16	90.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1X1I8@135613|Chromatiales	135613|Chromatiales	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
YYD3_k127_2486509_0	401053.AciPR4_2252	2.641e-49	198.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YYD3_k127_2486509_1	926566.Terro_2784	1.046e-35	139.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_2486509_3	1121035.AUCH01000003_gene1261	9.872e-16	80.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2WGJT@28216|Betaproteobacteria,2KU7W@206389|Rhodocyclales	206389|Rhodocyclales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
YYD3_k127_24958_6	574087.Acear_1461	1.241e-67	242.0	COG0124@1|root,COG0124@2|Bacteria,1UIUT@1239|Firmicutes,25ESP@186801|Clostridia,3WCAR@53433|Halanaerobiales	186801|Clostridia	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
YYD3_k127_24958_1	518766.Rmar_0932	9.33e-109	363.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1FIT7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YYD3_k127_24958_5	1340493.JNIF01000003_gene4545	3.836e-69	248.0	COG0083@1|root,COG0083@2|Bacteria,3Y2ZV@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
YYD3_k127_24958_3	237368.SCABRO_03813	1.324e-80	286.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
YYD3_k127_24958_2	404589.Anae109_1579	1.251e-102	339.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD3_k127_24958_0	234267.Acid_1531	1.424e-175	566.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
YYD3_k127_24958_4	234267.Acid_4621	6.723e-75	269.0	29ZE1@1|root,30MD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_24958_7	861299.J421_1461	1.982e-43	178.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
YYD3_k127_24958_8	886293.Sinac_6279	4.189e-33	134.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_24958_9	639030.JHVA01000001_gene635	2.811e-32	134.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria,2JI98@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD3_k127_2527180_1	1340493.JNIF01000004_gene791	2.056e-27	122.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene791|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2527180_0	309807.SRU_0977	5.558e-100	345.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2527180_2	1122621.ATZA01000006_gene723	6.444e-11	65.0	COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,1IV1K@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD3_k127_2535415_11	448385.sce0934	2.377e-07	54.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YYD3_k127_2535415_2	1382359.JIAL01000001_gene519	2.132e-96	323.0	COG1173@1|root,COG1173@2|Bacteria,3Y45P@57723|Acidobacteria,2JIKH@204432|Acidobacteriia	204432|Acidobacteriia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
YYD3_k127_2535415_1	1267533.KB906737_gene1964	8.301e-114	377.0	COG0601@1|root,COG0601@2|Bacteria,3Y437@57723|Acidobacteria,2JHY6@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YYD3_k127_2535415_6	316274.Haur_3900	1.796e-74	260.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_2535415_0	926550.CLDAP_39770	3.307e-114	377.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD3_k127_2535415_4	1122176.KB903551_gene4256	3.779e-84	293.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,1IU97@117747|Sphingobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
YYD3_k127_2535415_3	251229.Chro_1203	2.118e-90	308.0	COG0451@1|root,COG0451@2|Bacteria,1GIYN@1117|Cyanobacteria,3VN01@52604|Pleurocapsales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	-
YYD3_k127_2535415_9	555793.WSK_4047	3.776e-26	119.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2535415_10	1121396.KB893101_gene523	1.551e-11	68.0	COG2331@1|root,COG2331@2|Bacteria,1NGC1@1224|Proteobacteria,42W5D@68525|delta/epsilon subdivisions,2WRAY@28221|Deltaproteobacteria,2MKW8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YYD3_k127_2535415_7	298653.Franean1_3293	1.437e-43	176.0	28JDP@1|root,32SV2@2|Bacteria,2IPQY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2535415_5	404589.Anae109_3354	1.216e-83	299.0	COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
YYD3_k127_2535415_8	404589.Anae109_3355	3.248e-39	156.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YYD3_k127_2539769_1	234267.Acid_2650	1.505e-101	344.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K07799,ko:K21135	ko02020,map02020	M00648,M00822	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.35,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD3_k127_2539769_0	1173023.KE650771_gene3661	0.0	1072.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria,1JIE7@1189|Stigonemataceae	1117|Cyanobacteria	V	MMPL family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
YYD3_k127_2542024_0	1298867.AUES01000042_gene3563	0.0	1405.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
YYD3_k127_2542024_4	935948.KE386494_gene753	8.684e-51	190.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,42GIT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
YYD3_k127_2542024_5	234267.Acid_5659	4.947e-50	187.0	COG0204@1|root,COG0204@2|Bacteria,3Y4EM@57723|Acidobacteria	57723|Acidobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
YYD3_k127_2542024_3	684949.ATTJ01000001_gene1838	9.633e-69	250.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
YYD3_k127_2542024_1	671143.DAMO_0060	1.978e-290	912.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168,ko:K07479	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
YYD3_k127_2542024_2	1047013.AQSP01000139_gene2359	1.497e-80	282.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
YYD3_k127_2542024_6	477184.KYC_22916	1.56e-42	161.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2VRG2@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
YYD3_k127_2542024_7	247639.MGP2080_06722	2.71e-05	53.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,1J704@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4771 Outer membrane receptor for ferrienterochelin and colicins	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_2553001_1	1267535.KB906767_gene3727	7.392e-73	251.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
YYD3_k127_2553001_2	395965.Msil_0410	1.278e-36	147.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2553001_3	1165096.ARWF01000001_gene1596	1.408e-23	110.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2553001_0	316274.Haur_0703	0.0	1068.0	COG0826@1|root,COG0826@2|Bacteria,2G8DM@200795|Chloroflexi,376GI@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
YYD3_k127_2555474_2	247490.KSU1_B0100	6.174e-160	512.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
YYD3_k127_2555474_1	278963.ATWD01000001_gene2416	3.36e-291	904.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
YYD3_k127_2555474_0	1124780.ANNU01000056_gene3466	0.0	1063.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia	976|Bacteroidetes	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
YYD3_k127_2555474_4	365046.Rta_24780	5.792e-64	230.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2VIDM@28216|Betaproteobacteria,4AAPG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Amidohydrolase 2	-	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
YYD3_k127_2555474_3	497964.CfE428DRAFT_4312	8.101e-87	296.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
YYD3_k127_2564122_2	1463895.JODA01000040_gene2349	8.963e-71	246.0	COG3361@1|root,COG3361@2|Bacteria,2H1AK@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
YYD3_k127_2564122_3	871968.DESME_03495	4.672e-60	214.0	COG0564@1|root,COG0564@2|Bacteria,1TSPG@1239|Firmicutes,24D6E@186801|Clostridia,260NQ@186807|Peptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD3_k127_2564122_0	234267.Acid_0690	3.182e-179	582.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
YYD3_k127_2564122_1	671143.DAMO_2419	3.135e-71	247.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD3_k127_2618170_2	220664.PFL_2151	1.036e-12	67.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,1RZTH@1236|Gammaproteobacteria,1YTN6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,YCII
YYD3_k127_2618170_1	69395.JQLZ01000005_gene3645	4.136e-54	204.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2618170_3	234267.Acid_3837	0.0005916	52.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_2618170_0	234267.Acid_1535	4.036e-85	293.0	COG0739@1|root,COG0739@2|Bacteria,3Y3GS@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
YYD3_k127_262073_2	234267.Acid_0792	4.261e-09	65.0	COG5662@1|root,COG5662@2|Bacteria,3Y4S0@57723|Acidobacteria	57723|Acidobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD3_k127_262073_0	234267.Acid_7940	8.474e-35	140.0	COG1595@1|root,COG1595@2|Bacteria,3Y5K8@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_262073_1	555793.WSK_4047	2.028e-25	120.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2635324_3	3847.GLYMA13G12018.1	1.561e-11	64.0	2CRR6@1|root,2R8TJ@2759|Eukaryota,382HR@33090|Viridiplantae,3GRZ3@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2635324_1	234267.Acid_2901	2.104e-53	193.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
YYD3_k127_2635324_2	1476973.JMMB01000007_gene1610	4.585e-13	79.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,25UH9@186804|Peptostreptococcaceae	186801|Clostridia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.5	ko:K20445	ko00760,ko01120,map00760,map01120	-	R01720	RC00589	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
YYD3_k127_2635324_0	935840.JAEQ01000018_gene2029	2.466e-201	643.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	-	ko:K15064	ko00627,ko01120,map00627,map01120	-	R09270	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_2660513_1	1396418.BATQ01000168_gene1817	1.553e-46	175.0	COG4785@1|root,COG4785@2|Bacteria,46WU1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	May be involved in cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2660513_0	1415780.JPOG01000001_gene167	8.245e-66	235.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,1QQS9@1224|Proteobacteria,1SKP7@1236|Gammaproteobacteria,1XA8Y@135614|Xanthomonadales	135614|Xanthomonadales	CO	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
YYD3_k127_2660513_2	1267535.KB906767_gene4396	3.702e-42	162.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2668507_8	1340493.JNIF01000003_gene2186	2.853e-11	66.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YYD3_k127_2668507_9	401053.AciPR4_1224	2.4e-10	69.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_2668507_2	1192034.CAP_3992	2.295e-73	249.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
YYD3_k127_2668507_10	1340493.JNIF01000004_gene904	8.868e-08	62.0	2EMD6@1|root,33F24@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2668507_3	864051.BurJ1DRAFT_2043	3.11e-40	155.0	COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,2VT15@28216|Betaproteobacteria,1KMD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
YYD3_k127_2668507_4	926566.Terro_3400	2.257e-27	123.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_2668507_1	706587.Desti_1126	2.853e-79	276.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2MR0J@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
YYD3_k127_2668507_0	1210884.HG799468_gene13566	2.382e-109	358.0	COG4221@1|root,COG4221@2|Bacteria,2IYGT@203682|Planctomycetes	203682|Planctomycetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD3_k127_2668507_7	391612.CY0110_28224	1.214e-14	85.0	2DBIE@1|root,32TXH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2668507_5	1082931.KKY_123	3.216e-17	93.0	2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2678351_6	1121104.AQXH01000004_gene116	0.0001137	51.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2678351_4	344747.PM8797T_31810	4.539e-55	218.0	COG0515@1|root,COG0515@2|Bacteria,2IY6U@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
YYD3_k127_2678351_5	521674.Plim_3811	2.559e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2678351_1	1267535.KB906767_gene4866	3.705e-121	398.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3,DUF1566
YYD3_k127_2678351_3	1144305.PMI02_01782	1.388e-58	215.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2K2S7@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_2678351_0	204669.Acid345_2578	1.994e-244	786.0	COG0412@1|root,COG0515@1|root,COG1262@1|root,COG0412@2|Bacteria,COG0515@2|Bacteria,COG1262@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_2678351_2	886293.Sinac_0668	2.233e-69	252.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_269028_3	234267.Acid_6647	4.526e-07	59.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_269028_1	330214.NIDE3490	7.99e-43	163.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
YYD3_k127_269028_0	1242864.D187_007741	1.223e-65	234.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
YYD3_k127_269028_2	90814.KL370891_gene747	6.11e-29	119.0	2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
YYD3_k127_2712418_0	489825.LYNGBM3L_45680	2.769e-42	167.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1G2T0@1117|Cyanobacteria,1H6XI@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Globin,Guanylate_cyc,HAMP,dCache_1
YYD3_k127_2712418_3	926566.Terro_3405	3.383e-24	116.0	COG2027@1|root,COG2027@2|Bacteria	2|Bacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	DUF3738,Peptidase_S13
YYD3_k127_2712418_2	234267.Acid_7691	9.832e-25	110.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2712418_1	1178825.ALIH01000019_gene1212	2.439e-27	123.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,He_PIG,N_methyl
YYD3_k127_2714877_3	700598.Niako_0759	5.456e-20	101.0	COG0671@1|root,COG0671@2|Bacteria,4NF34@976|Bacteroidetes	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD3_k127_2714877_2	247633.GP2143_17801	6.592e-40	153.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2714877_1	247633.GP2143_17796	6.898e-66	237.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2714877_0	880073.Calab_3793	1.7e-209	664.0	COG0442@1|root,COG0442@2|Bacteria,2NNKF@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
YYD3_k127_2714877_4	478801.Ksed_14660	1.53e-10	69.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
YYD3_k127_2763284_6	1267535.KB906767_gene5107	8.464e-16	78.0	COG0577@1|root,COG0577@2|Bacteria,3Y76A@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2763284_2	886293.Sinac_4341	5.206e-118	387.0	COG1171@1|root,COG1171@2|Bacteria,2IYNJ@203682|Planctomycetes	203682|Planctomycetes	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_2763284_4	1380391.JIAS01000011_gene4657	9.372e-37	143.0	COG0640@1|root,COG0640@2|Bacteria,1N8QA@1224|Proteobacteria,2UC02@28211|Alphaproteobacteria,2JTRR@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
YYD3_k127_2763284_1	1379270.AUXF01000002_gene1515	5.658e-121	398.0	COG0626@1|root,COG0626@2|Bacteria,1ZUJ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
YYD3_k127_2763284_3	452637.Oter_1378	5.535e-59	213.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	yobB	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
YYD3_k127_2763284_0	861299.J421_6006	6.275e-150	505.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2763284_8	401053.AciPR4_3621	1.254e-05	55.0	COG1629@1|root,COG1629@2|Bacteria,3Y67H@57723|Acidobacteria,2JP0D@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
YYD3_k127_2822553_1	886293.Sinac_6615	4.447e-53	193.0	COG1253@1|root,COG1253@2|Bacteria,2IYEG@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YYD3_k127_2822553_0	448385.sce8113	1e-323	1020.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
YYD3_k127_2822553_2	1122951.ATUE01000006_gene1188	1.285e-36	145.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,3NJHC@468|Moraxellaceae	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	mexE	-	-	ko:K03585,ko:K07799,ko:K18298,ko:K18901,ko:K19586,ko:K19595	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00641,M00646,M00647,M00648,M00698,M00699,M00718,M00767,M00768,M00769	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.25,2.A.6.2.34,2.A.6.2.47,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD3_k127_2823982_5	857087.Metme_1245	1.616e-34	134.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1XDUR@135618|Methylococcales	135618|Methylococcales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
YYD3_k127_2823982_7	631454.N177_1712	4.724e-19	99.0	COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,2TVB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	regulatory protein LysR	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_1,HTH_17,PBP_like
YYD3_k127_2823982_2	1267535.KB906767_gene1287	2.395e-61	225.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_2823982_8	555793.WSK_4186	2.039e-17	87.0	2C42J@1|root,336T0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2823982_6	404589.Anae109_1975	8.366e-26	111.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2823982_1	251221.35213172	1.479e-157	509.0	COG2133@1|root,COG2133@2|Bacteria,1G06W@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_2823982_3	1267535.KB906767_gene774	1.984e-55	200.0	2DP3Z@1|root,342RZ@2|Bacteria,3Y891@57723|Acidobacteria,2JNCK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2823982_4	1192034.CAP_1726	4.569e-45	173.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,43CA0@68525|delta/epsilon subdivisions,2X7KG@28221|Deltaproteobacteria,2YVW6@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_2823982_0	1267535.KB906767_gene1169	1.067e-196	624.0	COG1502@1|root,COG1502@2|Bacteria,3Y2GD@57723|Acidobacteria	57723|Acidobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
YYD3_k127_2824268_0	1100721.ALKO01000020_gene911	9.892e-259	815.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9Z9@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
YYD3_k127_2831185_2	330214.NIDE4311	2.329e-35	142.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
YYD3_k127_2831185_0	330214.NIDE4312	5.625e-134	433.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD3_k127_2831185_1	243233.MCA0142	3.409e-128	423.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
YYD3_k127_2836004_1	234267.Acid_0698	1.091e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,3Y50V@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_2836004_3	1267534.KB906759_gene2025	8.349e-34	136.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
YYD3_k127_2836004_0	1128421.JAGA01000001_gene2170	2.246e-118	391.0	COG3569@1|root,COG3569@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	topI	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
YYD3_k127_2836004_2	298654.FraEuI1c_4104	1.733e-43	176.0	28JDP@1|root,32SV2@2|Bacteria,2IPQY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2856292_1	1444711.CCJF01000005_gene546	2.003e-141	491.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
YYD3_k127_2856292_0	880072.Desac_2709	6.326e-309	956.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2MQVI@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
YYD3_k127_2856292_2	1121468.AUBR01000021_gene2827	9.676e-27	115.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
YYD3_k127_2857493_2	243090.RB4667	1.141e-130	427.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2857493_1	234267.Acid_5749	1.913e-207	674.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2857493_6	1499967.BAYZ01000090_gene4936	4.584e-29	130.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YYD3_k127_2857493_0	1340493.JNIF01000003_gene3855	1.255e-229	738.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XC@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2857493_7	1123242.JH636435_gene2867	8.87e-14	73.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YYD3_k127_2857493_3	65393.PCC7424_5183	1.938e-105	350.0	COG3751@1|root,COG3751@2|Bacteria,1G4YQ@1117|Cyanobacteria,3KJJV@43988|Cyanothece	1117|Cyanobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
YYD3_k127_2857493_4	272134.KB731325_gene637	9.61e-56	199.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
YYD3_k127_2857769_2	644076.SCH4B_2975	0.0001843	46.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,4NA9D@97050|Ruegeria	28211|Alphaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YYD3_k127_2857769_1	997346.HMPREF9374_2994	1.685e-126	426.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,27AY6@186824|Thermoactinomycetaceae	91061|Bacilli	S	ABC transporter C-terminal domain	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
YYD3_k127_2857769_0	234267.Acid_7263	5.931e-219	693.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
YYD3_k127_2870271_2	1267535.KB906767_gene3835	1.688e-65	239.0	COG0577@1|root,COG0577@2|Bacteria,3Y47F@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2870271_3	234267.Acid_4687	1.777e-44	163.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_2870271_1	1123073.KB899242_gene1091	4.217e-139	449.0	COG0451@1|root,COG0451@2|Bacteria,1QP8J@1224|Proteobacteria,1RP88@1236|Gammaproteobacteria,1X5KQ@135614|Xanthomonadales	135614|Xanthomonadales	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD3_k127_2870271_0	234267.Acid_7841	2.441e-153	511.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_289472_1	1278073.MYSTI_07499	1.338e-47	173.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2YV8R@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
YYD3_k127_289472_0	234267.Acid_2416	5.157e-68	235.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
YYD3_k127_2901659_1	234267.Acid_7680	1.375e-96	325.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2901659_5	1097668.BYI23_B010930	5.707e-09	57.0	COG1595@1|root,COG1595@2|Bacteria,1NCTM@1224|Proteobacteria,2WFXR@28216|Betaproteobacteria,1K8YU@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Protein of unknown function (DUF3489)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3489
YYD3_k127_2901659_4	234267.Acid_2897	4.585e-09	63.0	COG0433@1|root,COG0582@1|root,COG0433@2|Bacteria,COG0582@2|Bacteria,3Y8KW@57723|Acidobacteria	57723|Acidobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
YYD3_k127_2901659_6	234267.Acid_3725	4.286e-07	59.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2901659_2	555793.WSK_1442	2.209e-14	84.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2901659_0	1122970.AUHC01000021_gene2458	2.291e-177	566.0	COG3794@1|root,COG3794@2|Bacteria,1R29B@1224|Proteobacteria	1224|Proteobacteria	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
YYD3_k127_2903007_3	697282.Mettu_4103	6.904e-65	224.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,1XFAS@135618|Methylococcales	135618|Methylococcales	C	PFAM 2Fe-2S -binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
YYD3_k127_2903007_0	1340493.JNIF01000004_gene24	3.596e-212	683.0	COG1529@1|root,COG1529@2|Bacteria,3Y77V@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
YYD3_k127_2903007_4	192952.MM_2290	2.12e-07	57.0	COG0860@1|root,arCOG08705@1|root,arCOG08705@2157|Archaea,arCOG09691@2157|Archaea,2Y4YX@28890|Euryarchaeota	28890|Euryarchaeota	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
YYD3_k127_2903007_2	1123248.KB893386_gene1868	2.574e-166	539.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YYD3_k127_2903007_1	234267.Acid_1193	9.01e-177	562.0	COG0821@1|root,COG0821@2|Bacteria,3Y2GU@57723|Acidobacteria	57723|Acidobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
YYD3_k127_2903793_2	118161.KB235919_gene6110	1.389e-14	80.0	COG0823@1|root,COG0823@2|Bacteria,1G8I3@1117|Cyanobacteria	1117|Cyanobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
YYD3_k127_2903793_4	886293.Sinac_4051	6.437e-07	54.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_2903793_1	234267.Acid_6847	1.826e-33	135.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_2903793_3	1267535.KB906767_gene4499	1.93e-13	72.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_2903793_0	234267.Acid_2447	4.063e-72	257.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_2903793_5	1408813.AYMG01000018_gene5059	0.0002677	46.0	COG0346@1|root,COG0346@2|Bacteria,4NSWT@976|Bacteroidetes	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_2907555_0	1267535.KB906767_gene2350	2.496e-318	982.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_2907555_2	1123228.AUIH01000015_gene543	2.796e-56	206.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
YYD3_k127_2907555_1	204669.Acid345_2092	2.955e-196	626.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria,2JI53@204432|Acidobacteriia	204432|Acidobacteriia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
YYD3_k127_2907555_3	1379270.AUXF01000005_gene787	5.293e-51	186.0	COG1968@1|root,COG1968@2|Bacteria,1ZU3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
YYD3_k127_2918847_1	497964.CfE428DRAFT_1596	1.061e-57	204.0	COG1250@1|root,COG1250@2|Bacteria,46TNQ@74201|Verrucomicrobia	74201|Verrucomicrobia	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2918847_0	344747.PM8797T_24141	6.983e-142	460.0	COG1520@1|root,COG1520@2|Bacteria,2IYK2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_292456_5	1267535.KB906767_gene5271	5.928e-50	182.0	COG1187@1|root,COG1187@2|Bacteria,3Y3CQ@57723|Acidobacteria,2JHMG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD3_k127_292456_3	1267535.KB906767_gene5272	3.993e-58	208.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria,2JHVE@204432|Acidobacteriia	204432|Acidobacteriia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
YYD3_k127_292456_2	639030.JHVA01000001_gene1708	2.382e-61	220.0	COG1354@1|root,COG1354@2|Bacteria,3Y458@57723|Acidobacteria,2JIGP@204432|Acidobacteriia	204432|Acidobacteriia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
YYD3_k127_292456_0	204669.Acid345_3860	1.212e-139	450.0	COG0180@1|root,COG0180@2|Bacteria,3Y2VN@57723|Acidobacteria,2JHXI@204432|Acidobacteriia	204432|Acidobacteriia	J	aminoacyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
YYD3_k127_292456_6	1125863.JAFN01000001_gene1124	2.917e-43	174.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
YYD3_k127_292456_1	1232410.KI421412_gene411	2.872e-131	431.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
YYD3_k127_292456_4	338966.Ppro_3375	2.091e-56	202.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,43T66@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
YYD3_k127_2933165_0	903818.KI912268_gene2106	1.702e-91	316.0	COG0348@1|root,COG0348@2|Bacteria,3Y3H4@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YYD3_k127_2941638_1	595537.Varpa_3689	3.744e-05	48.0	COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,2VSC7@28216|Betaproteobacteria,4AE1X@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
YYD3_k127_2941638_0	234267.Acid_2031	6.599e-82	288.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_2944282_0	1303518.CCALI_02490	1.002e-50	188.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_2944282_3	555793.WSK_4047	3.976e-19	98.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2944282_4	639030.JHVA01000001_gene1885	6.731e-16	84.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2944282_2	555793.WSK_4047	4.524e-21	106.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2944282_5	247633.GP2143_17801	1.86e-11	76.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_2944282_1	1449346.JQMO01000002_gene1048	1.285e-32	137.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,2M494@2063|Kitasatospora	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_2944892_5	545697.HMPREF0216_03037	4.568e-08	64.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,24EN3@186801|Clostridia,36GDY@31979|Clostridiaceae	186801|Clostridia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
YYD3_k127_2944892_1	1121090.KB894689_gene333	5.939e-89	302.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus	91061|Bacilli	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YYD3_k127_2944892_3	1122915.AUGY01000118_gene6542	5.722e-65	233.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
YYD3_k127_2944892_2	886293.Sinac_5427	4.483e-72	249.0	COG3485@1|root,COG3485@2|Bacteria,2IYK6@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
YYD3_k127_2944892_4	1267533.KB906734_gene4044	1.748e-27	123.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria,2JK5T@204432|Acidobacteriia	2|Bacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978,ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
YYD3_k127_2944892_0	204669.Acid345_4052	2.474e-112	380.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
YYD3_k127_2981739_3	1144310.PMI07_003756	3.385e-09	61.0	COG3744@1|root,COG3744@2|Bacteria,1N2T0@1224|Proteobacteria,2UC39@28211|Alphaproteobacteria,4BGKQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_2981739_1	1267535.KB906767_gene705	1.41e-88	306.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
YYD3_k127_2981739_0	234267.Acid_3515	3.346e-251	805.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_2981739_2	483219.LILAB_07275	7.512e-12	76.0	2EN73@1|root,33FUY@2|Bacteria,1NHF0@1224|Proteobacteria,43C5M@68525|delta/epsilon subdivisions,2X7FW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
YYD3_k127_2992867_2	189753.AXAS01000041_gene2526	1.242e-78	275.0	COG0385@1|root,COG0385@2|Bacteria,1N9IH@1224|Proteobacteria	1224|Proteobacteria	S	Bile acid	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
YYD3_k127_2992867_3	1160707.AJIK01000039_gene2133	3.643e-48	183.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,26EQ5@186818|Planococcaceae	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
YYD3_k127_2992867_0	234267.Acid_2664	1.676e-222	700.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
YYD3_k127_2992867_4	234267.Acid_1401	9.025e-40	155.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_2992867_1	234267.Acid_5869	1.082e-98	332.0	COG1629@1|root,COG4771@2|Bacteria,3Y368@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_2996004_5	867845.KI911784_gene148	1.472e-14	87.0	COG1807@1|root,COG1807@2|Bacteria,2GA8T@200795|Chloroflexi,374SQ@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
YYD3_k127_2996004_2	1380763.BG53_00155	3.418e-43	160.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,26Y4P@186822|Paenibacillaceae	91061|Bacilli	FG	HIT family	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
YYD3_k127_2996004_4	485913.Krac_3321	1.646e-29	121.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	FA_hydroxylase,Polyketide_cyc2
YYD3_k127_2996004_3	247490.KSU1_D0285	8.074e-43	160.0	2CA4A@1|root,32RQK@2|Bacteria,2J0BM@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
YYD3_k127_2996004_0	1278073.MYSTI_02965	2.7e-65	234.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
YYD3_k127_2996004_1	1120972.AUMH01000005_gene911	5.453e-53	211.0	COG0129@1|root,COG0129@2|Bacteria,1UYPZ@1239|Firmicutes,4HCGG@91061|Bacilli	91061|Bacilli	EG	Dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
YYD3_k127_3000954_3	330214.NIDE2743	4.36e-48	182.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,3J0B6@40117|Nitrospirae	40117|Nitrospirae	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
YYD3_k127_3000954_7	204669.Acid345_4210	5.071e-06	50.0	2EMVM@1|root,33FHV@2|Bacteria,3Y5YS@57723|Acidobacteria,2JK39@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3000954_5	639030.JHVA01000001_gene1523	1.048e-21	100.0	2B6R1@1|root,31ZPU@2|Bacteria,3Y4VP@57723|Acidobacteria,2JJGV@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3000954_4	1232410.KI421419_gene2515	3.313e-43	166.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,42XQK@68525|delta/epsilon subdivisions,2WSNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
YYD3_k127_3000954_6	234267.Acid_4414	6.063e-16	81.0	COG1872@1|root,COG1872@2|Bacteria,3Y5S4@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
YYD3_k127_3000954_2	671143.DAMO_2290	1.878e-56	207.0	COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria	2|Bacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
YYD3_k127_3000954_1	1396418.BATQ01000119_gene3117	7.267e-75	266.0	COG1273@1|root,COG1273@2|Bacteria,46SB0@74201|Verrucomicrobia,2IVP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Ku70/Ku80 beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Ku
YYD3_k127_3000954_0	309807.SRU_0737	2.052e-94	320.0	COG0432@1|root,COG0432@2|Bacteria,4PE9F@976|Bacteroidetes,1FIKK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pfam Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3032777_4	105422.BBPM01000005_gene6230	6.821e-08	57.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2I9ID@201174|Actinobacteria,2NGFK@228398|Streptacidiphilus	201174|Actinobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_4,SpoIIE
YYD3_k127_3032777_0	1267535.KB906767_gene629	1.34e-198	629.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3032777_1	234267.Acid_4169	3.147e-141	460.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YYD3_k127_3032777_3	1121405.dsmv_3801	1.371e-64	231.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2X5JU@28221|Deltaproteobacteria,2MPFA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
YYD3_k127_3032777_2	156889.Mmc1_2862	2.387e-92	315.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
YYD3_k127_3045228_1	1340493.JNIF01000003_gene1545	2.158e-16	79.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
YYD3_k127_3045228_0	290397.Adeh_2972	2.078e-76	273.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
YYD3_k127_3092931_0	234267.Acid_1156	4.076e-221	689.0	COG0380@1|root,COG0380@2|Bacteria,3Y3X7@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
YYD3_k127_3092931_1	744872.Spica_1973	9.288e-162	520.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,2J5CJ@203691|Spirochaetes	203691|Spirochaetes	E	Amino-acid N-acetyltransferase	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
YYD3_k127_3092931_2	1385935.N836_06940	4.66e-09	61.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1GBWR@1117|Cyanobacteria	1117|Cyanobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
YYD3_k127_3092931_3	243233.MCA1721	7.478e-09	58.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1S54R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD3_k127_311111_4	926566.Terro_0274	1.68e-10	70.0	COG1629@1|root,COG4771@2|Bacteria,3Y42A@57723|Acidobacteria,2JIME@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_311111_6	1101189.AQUO01000002_gene728	7.344e-05	45.0	COG1961@1|root,COG1961@2|Bacteria,1PFVE@1224|Proteobacteria,2V7HD@28211|Alphaproteobacteria,2PYM2@265|Paracoccus	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Zn_ribbon_recom
YYD3_k127_311111_1	1249627.D779_4106	1.262e-52	195.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1WYPS@135613|Chromatiales	135613|Chromatiales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
YYD3_k127_311111_2	298653.Franean1_6533	3.315e-48	176.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4ESSJ@85013|Frankiales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
YYD3_k127_311111_5	696281.Desru_3317	8.543e-06	58.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI,Glyco_hydro_19,LysM,PG_binding_1,Peptidase_C39_2,SLT
YYD3_k127_311111_0	204669.Acid345_1442	8.07e-85	295.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria,2JINN@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
YYD3_k127_311111_3	357808.RoseRS_2786	7.64e-21	99.0	COG1520@1|root,COG1520@2|Bacteria,2G9GE@200795|Chloroflexi,3774I@32061|Chloroflexia	32061|Chloroflexia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3128029_1	639030.JHVA01000001_gene1982	3.571e-12	79.0	COG1629@1|root,COG4771@2|Bacteria,3Y3A5@57723|Acidobacteria,2JNZT@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3128029_2	1125701.HMPREF1221_00163	4.95e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
YYD3_k127_3128029_0	204669.Acid345_0920	4.284e-118	395.0	COG0457@1|root,COG0457@2|Bacteria,3Y3HT@57723|Acidobacteria,2JHSD@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_3129000_4	2903.EOD40718	3.586e-52	189.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
YYD3_k127_3129000_9	1210884.HG799463_gene9325	3.174e-23	106.0	COG2172@1|root,COG2172@2|Bacteria,2J0BZ@203682|Planctomycetes	203682|Planctomycetes	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
YYD3_k127_3129000_6	1382359.JIAL01000001_gene2134	1.57e-37	145.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_3129000_8	1288826.MSNKSG1_14877	3.698e-31	127.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,468FQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD3_k127_3129000_3	926550.CLDAP_23740	7.719e-69	243.0	COG1218@1|root,COG1218@2|Bacteria	2|Bacteria	P	3'(2'),5'-bisphosphate nucleotidase activity	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
YYD3_k127_3129000_0	1041930.Mtc_1045	1.084e-112	374.0	arCOG01186@1|root,arCOG01186@2157|Archaea	2157|Archaea	G	Mn2 dependent serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD3_k127_3129000_5	330214.NIDE3769	1.067e-42	162.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
YYD3_k127_3129000_10	483219.LILAB_04455	0.0009997	50.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria,42X7Z@68525|delta/epsilon subdivisions,2WSMB@28221|Deltaproteobacteria,2Z2C0@29|Myxococcales	28221|Deltaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
YYD3_k127_3129000_1	153721.MYP_1941	4.592e-82	282.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD3_k127_3129000_2	204669.Acid345_0180	1.071e-73	256.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
YYD3_k127_3129000_7	1234595.C725_1063	2.062e-33	136.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,4BQGQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
YYD3_k127_3140549_2	102129.Lepto7375DRAFT_2079	7.457e-142	470.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,1H9BF@1150|Oscillatoriales	1117|Cyanobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_3140549_4	1238182.C882_0658	2.833e-76	275.0	COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,2JRIP@204441|Rhodospirillales	204441|Rhodospirillales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
YYD3_k127_3140549_3	1267535.KB906767_gene5186	3.575e-101	337.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria,2JHUP@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
YYD3_k127_3140549_6	518766.Rmar_1382	5.776e-10	61.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YYD3_k127_3140549_7	1183438.GKIL_0990	9.758e-09	59.0	COG0723@1|root,COG0723@2|Bacteria,1G03Q@1117|Cyanobacteria	1117|Cyanobacteria	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
YYD3_k127_3140549_0	234267.Acid_7841	6.423e-186	629.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3140549_1	1089545.KB913037_gene1118	3.124e-164	526.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4EA5C@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YYD3_k127_3140549_5	234267.Acid_2120	1.593e-17	83.0	COG1361@1|root,COG1361@2|Bacteria,3Y2G0@57723|Acidobacteria	57723|Acidobacteria	M	Alpha-L-arabinofuranosidase B, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,LTD,NPCBM_assoc
YYD3_k127_3142324_5	869210.Marky_1855	2.957e-36	140.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
YYD3_k127_3142324_1	1111069.TCCBUS3UF1_20210	1.015e-115	383.0	COG0508@1|root,COG0508@2|Bacteria,1WIIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_3142324_4	118163.Ple7327_0384	1.686e-38	152.0	COG0412@1|root,COG0412@2|Bacteria,1G1CY@1117|Cyanobacteria	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
YYD3_k127_3142324_3	204773.HEAR2529	3.954e-77	270.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,1RDAY@1224|Proteobacteria,2VQGW@28216|Betaproteobacteria,4777D@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH
YYD3_k127_3142324_2	1379270.AUXF01000007_gene1056	4.066e-84	289.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
YYD3_k127_3142324_0	1123024.AUII01000032_gene3795	4.236e-211	666.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4DXX6@85010|Pseudonocardiales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
YYD3_k127_3156754_1	1278073.MYSTI_05613	4.747e-96	347.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
YYD3_k127_3156754_4	1267534.KB906755_gene4635	2.355e-26	119.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_3156754_5	639030.JHVA01000001_gene1885	1.022e-25	110.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3156754_3	555793.WSK_4047	8.583e-28	124.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3156754_0	518766.Rmar_2513	9.234e-111	382.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1FIPN@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	GO:0000175,GO:0000178,GO:0000932,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0022613,GO:0032991,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0035770,GO:0036464,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354,GO:1990904	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
YYD3_k127_3156754_2	1232410.KI421421_gene3618	7.993e-35	151.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,43S5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3156754_6	645465.ACUR01000590_gene3479	4.026e-12	74.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD3_k127_3164899_1	1340493.JNIF01000003_gene3519	5.569e-65	250.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3164899_0	290397.Adeh_3048	7.766e-117	396.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria	1224|Proteobacteria	T	flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
YYD3_k127_3164899_2	1123257.AUFV01000010_gene3270	2.044e-10	66.0	COG3576@1|root,COG3576@2|Bacteria,1N8Z5@1224|Proteobacteria,1SEAI@1236|Gammaproteobacteria,1XB3T@135614|Xanthomonadales	135614|Xanthomonadales	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3167692_5	580327.Tthe_1743	1.257e-18	90.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,42EX0@68295|Thermoanaerobacterales	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
YYD3_k127_3167692_2	765869.BDW_00630	3.748e-53	197.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2MUQW@213481|Bdellovibrionales,2X5NA@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
YYD3_k127_3167692_1	1267534.KB906757_gene838	1.867e-86	292.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
YYD3_k127_3167692_4	1125863.JAFN01000001_gene28	5.771e-36	140.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
YYD3_k127_3167692_3	204669.Acid345_1215	2.927e-36	143.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria,2JJFX@204432|Acidobacteriia	204432|Acidobacteriia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
YYD3_k127_3167692_0	1209989.TepiRe1_0250	3.616e-166	536.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
YYD3_k127_318954_6	1122164.JHWF01000006_gene247	1.542e-05	54.0	COG2334@1|root,COG2334@2|Bacteria,1PGM7@1224|Proteobacteria,1RNPA@1236|Gammaproteobacteria,1JFP1@118969|Legionellales	118969|Legionellales	G	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD3_k127_318954_3	1122164.JHWF01000006_gene247	4.932e-14	79.0	COG2334@1|root,COG2334@2|Bacteria,1PGM7@1224|Proteobacteria,1RNPA@1236|Gammaproteobacteria,1JFP1@118969|Legionellales	118969|Legionellales	G	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
YYD3_k127_318954_0	383372.Rcas_4418	3.067e-180	587.0	COG4666@1|root,COG4666@2|Bacteria,2GAY7@200795|Chloroflexi,376X3@32061|Chloroflexia	32061|Chloroflexia	S	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
YYD3_k127_318954_1	644966.Tmar_2103	2.026e-88	303.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
YYD3_k127_318954_4	234267.Acid_6875	1.411e-07	62.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_318954_5	234267.Acid_7691	1.55e-07	57.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_318954_2	530564.Psta_3267	3.429e-14	78.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
YYD3_k127_3210701_1	1123242.JH636434_gene5534	2.474e-119	397.0	COG1541@1|root,COG1541@2|Bacteria,2IXI4@203682|Planctomycetes	203682|Planctomycetes	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
YYD3_k127_3210701_2	1403819.BATR01000130_gene4641	1.044e-27	117.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia,2IUVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
YYD3_k127_3210701_0	1210884.HG799464_gene11027	9.208e-149	480.0	COG0635@1|root,COG0635@2|Bacteria,2IY84@203682|Planctomycetes	203682|Planctomycetes	H	COG0635 Coproporphyrinogen III oxidase and related Fe-S	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_3219329_5	555793.WSK_4047	5.866e-10	63.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3219329_3	1236959.BAMT01000015_gene2849	8.559e-15	79.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3219329_1	1279017.AQYJ01000028_gene2525	1.498e-43	180.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3219329_6	715451.ambt_12010	2.79e-08	67.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3219329_4	649638.Trad_1403	3.415e-11	66.0	2DSMH@1|root,33GPM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3219329_0	1187851.A33M_4394	4.221e-53	190.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_3219329_2	1267534.KB906756_gene712	8.562e-32	130.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3219588_1	1444309.JAQG01000020_gene632	1.799e-30	138.0	COG2304@1|root,COG2304@2|Bacteria,1V0C8@1239|Firmicutes,4HDR1@91061|Bacilli,26RBX@186822|Paenibacillaceae	91061|Bacilli	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
YYD3_k127_3219588_0	335541.Swol_1716	2.673e-57	218.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,249E6@186801|Clostridia	186801|Clostridia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
YYD3_k127_3227182_1	166318.Syn8016DRAFT_2204	1.777e-06	55.0	COG0347@1|root,COG0347@2|Bacteria,1G5QJ@1117|Cyanobacteria,1H0HR@1129|Synechococcus	1117|Cyanobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YYD3_k127_3227182_0	509190.Cseg_2166	5.949e-14	84.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,2KF5N@204458|Caulobacterales	204458|Caulobacterales	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
YYD3_k127_3248411_0	1340493.JNIF01000003_gene2186	1.79e-284	908.0	COG1026@1|root,COG1026@2|Bacteria	2|Bacteria	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
YYD3_k127_3248411_1	1449076.JOOE01000001_gene1667	8.899e-57	210.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_326100_2	204669.Acid345_2541	3.146e-142	458.0	COG0057@1|root,COG0057@2|Bacteria,3Y2QC@57723|Acidobacteria,2JI8H@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
YYD3_k127_326100_3	671143.DAMO_1644	1.195e-85	298.0	COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria	2|Bacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
YYD3_k127_326100_6	443144.GM21_3412	3.61e-53	199.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,43SX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
YYD3_k127_326100_4	1267535.KB906767_gene439	3.728e-79	276.0	COG0859@1|root,COG0859@2|Bacteria,3Y6NF@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD3_k127_326100_8	880072.Desac_0949	3.154e-50	185.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MQQI@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
YYD3_k127_326100_5	1047013.AQSP01000111_gene1672	1.533e-76	269.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
YYD3_k127_326100_9	290397.Adeh_2610	2.136e-49	184.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
YYD3_k127_326100_7	1232410.KI421414_gene2851	4.215e-53	200.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,42NRP@68525|delta/epsilon subdivisions,2X5EK@28221|Deltaproteobacteria,43SA7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD3_k127_326100_13	639030.JHVA01000001_gene1582	1.416e-34	139.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJJZ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
YYD3_k127_326100_12	234267.Acid_5179	1.939e-37	148.0	COG0779@1|root,COG0779@2|Bacteria,3Y528@57723|Acidobacteria	57723|Acidobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
YYD3_k127_326100_1	1382359.JIAL01000001_gene1875	2.154e-161	520.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria,2JIAX@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
YYD3_k127_326100_0	234267.Acid_5181	2.174e-225	727.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
YYD3_k127_326100_15	234267.Acid_5182	7.538e-18	86.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
YYD3_k127_326100_14	1304880.JAGB01000001_gene235	1.724e-20	94.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
YYD3_k127_326100_10	502025.Hoch_5330	3.576e-47	181.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2YUCY@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,Peptidase_S8
YYD3_k127_326100_11	323261.Noc_0762	1.95e-42	162.0	COG4636@1|root,COG4636@2|Bacteria,1RJC2@1224|Proteobacteria,1S7B0@1236|Gammaproteobacteria,1X14J@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_3278808_0	1382359.JIAL01000001_gene1896	1.687e-175	561.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
YYD3_k127_3278808_3	278963.ATWD01000001_gene3139	2.289e-20	100.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria,2JN6E@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
YYD3_k127_3278808_2	1267534.KB906754_gene3435	3.66e-58	217.0	COG0760@1|root,COG0760@2|Bacteria,3Y42Z@57723|Acidobacteria,2JHQ4@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
YYD3_k127_3278808_4	401053.AciPR4_0433	4.816e-18	87.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
YYD3_k127_3278808_1	204669.Acid345_2476	1.129e-95	347.0	COG0729@1|root,COG4775@1|root,COG0729@2|Bacteria,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
YYD3_k127_3278808_6	926566.Terro_3238	0.0005731	50.0	COG0760@1|root,COG0760@2|Bacteria,3Y4KY@57723|Acidobacteria,2JJDJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
YYD3_k127_3278808_5	240015.ACP_0604	1.864e-08	59.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
YYD3_k127_3279533_1	1121448.DGI_0533	5.169e-78	289.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
YYD3_k127_3279533_3	1123376.AUIU01000012_gene1610	6.443e-28	120.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
YYD3_k127_3279533_0	1267535.KB906767_gene2893	2.473e-144	471.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_3279533_4	926566.Terro_2880	2.338e-05	55.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,3Y8DM@57723|Acidobacteria	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3279533_2	234267.Acid_4407	2.287e-66	233.0	COG3861@1|root,COG3861@2|Bacteria,3Y5WZ@57723|Acidobacteria	57723|Acidobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD3_k127_3285131_0	1265313.HRUBRA_01849	3.38e-131	431.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ_2
YYD3_k127_3285131_5	1532557.JL37_28495	2.396e-71	250.0	COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2VRVM@28216|Betaproteobacteria,3T1H7@506|Alcaligenaceae	28216|Betaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_3285131_6	1082931.KKY_83	2.59e-59	224.0	28JDP@1|root,32SV2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3285131_9	1340493.JNIF01000003_gene2360	3.666e-39	154.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	coxC	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K02477,ko:K07705,ko:K21696	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	LytTR,MHYT,Response_reg
YYD3_k127_3285131_1	118168.MC7420_5136	7.422e-106	349.0	COG3751@1|root,COG3751@2|Bacteria,1G4YQ@1117|Cyanobacteria,1HF5B@1150|Oscillatoriales	1117|Cyanobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
YYD3_k127_3285131_10	1449976.KALB_4136	2.879e-08	63.0	COG5517@1|root,COG5517@2|Bacteria,2IFNT@201174|Actinobacteria	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
YYD3_k127_3285131_8	99598.Cal7507_3404	1.991e-39	159.0	2F1DQ@1|root,33UEG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3285131_2	99598.Cal7507_3403	3.311e-91	316.0	COG0754@1|root,COG0754@2|Bacteria	2|Bacteria	E	glutathionylspermidine amidase activity	gsp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3484	CHAP,GSP_synth
YYD3_k127_3285131_7	99598.Cal7507_3402	2.656e-42	166.0	2EY4W@1|root,33RDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3285131_3	639030.JHVA01000001_gene307	2.041e-87	300.0	COG1064@1|root,COG1064@2|Bacteria,3Y2QS@57723|Acidobacteria,2JMMC@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc-binding dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_3285131_4	404589.Anae109_0599	6.435e-73	254.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase	pgl	-	2.7.1.12,3.1.1.31	ko:K00851,ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R01737,R02035	RC00002,RC00017,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
YYD3_k127_3303913_4	1298867.AUES01000037_gene748	4.095e-08	58.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG4070@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4070@2|Bacteria,1MU7T@1224|Proteobacteria,2TY6Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	QU	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3303913_2	861299.J421_0229	6.379e-36	139.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_3303913_1	1267535.KB906767_gene2100	4.517e-155	523.0	COG0577@1|root,COG0577@2|Bacteria,3Y6QF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_3303913_3	459495.SPLC1_S412060	3.779e-22	100.0	COG2402@1|root,COG2402@2|Bacteria,1G79E@1117|Cyanobacteria,1HBMU@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_3303913_0	234267.Acid_7841	6.726e-156	533.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3308382_6	1267533.KB906733_gene3415	9.957e-31	124.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
YYD3_k127_3308382_9	1313172.YM304_37650	1.184e-19	95.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_3308382_0	338963.Pcar_2420	4.394e-146	473.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,43U09@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
YYD3_k127_3308382_7	671143.DAMO_3159	5.784e-26	113.0	COG1595@1|root,COG1595@2|Bacteria,2NR5T@2323|unclassified Bacteria	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_3308382_10	321332.CYB_1660	9.011e-17	93.0	2DN50@1|root,32VJ4@2|Bacteria,1GND9@1117|Cyanobacteria,1H0SG@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
YYD3_k127_3308382_2	880073.Calab_2472	1.39e-95	337.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
YYD3_k127_3308382_5	880073.Calab_2471	5.114e-48	182.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
YYD3_k127_3308382_1	330214.NIDE1279	1.983e-106	354.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
YYD3_k127_3308382_4	1385511.N783_00755	2.185e-57	214.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes	1239|Firmicutes	P	sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
YYD3_k127_3308382_3	945713.IALB_0893	7.71e-92	322.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
YYD3_k127_3308382_8	765869.BDW_11300	1.235e-21	99.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2MTE2@213481|Bdellovibrionales,2WRSP@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
YYD3_k127_3323337_1	1123278.KB893574_gene6163	8.071e-203	639.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
YYD3_k127_3323337_11	1457250.BBMO01000002_gene2464	1.968e-51	189.0	COG0500@1|root,arCOG04734@2157|Archaea,2XWDH@28890|Euryarchaeota,23V0A@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD3_k127_3323337_8	1267534.KB906754_gene3106	2.876e-63	234.0	COG1228@1|root,COG1228@2|Bacteria,3Y539@57723|Acidobacteria,2JKT2@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_3323337_2	864051.BurJ1DRAFT_2775	6.12e-146	472.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2WEME@28216|Betaproteobacteria,1KN2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_3323337_5	1267534.KB906754_gene3418	7.38e-74	258.0	2F5SA@1|root,33YB5@2|Bacteria,3Y7SK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3323337_7	980584.AFPB01000161_gene2096	8.973e-64	235.0	COG0277@1|root,COG0277@2|Bacteria,4NGC5@976|Bacteroidetes,1I144@117743|Flavobacteriia,4075N@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
YYD3_k127_3323337_3	682795.AciX8_0457	2.786e-138	447.0	COG2255@1|root,COG2255@2|Bacteria,3Y2RP@57723|Acidobacteria,2JIMW@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
YYD3_k127_3323337_10	1267533.KB906734_gene4347	4.298e-57	212.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
YYD3_k127_3323337_14	234267.Acid_0324	7.383e-32	126.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
YYD3_k127_3323337_15	234267.Acid_0323	6.527e-12	69.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
YYD3_k127_3323337_13	234267.Acid_0322	3.114e-33	130.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
YYD3_k127_3323337_12	234267.Acid_0321	1.277e-41	154.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
YYD3_k127_3323337_6	204669.Acid345_4482	1.394e-68	241.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria,2JJCY@204432|Acidobacteriia	204432|Acidobacteriia	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
YYD3_k127_3323337_9	1487953.JMKF01000056_gene4467	3.573e-59	211.0	COG4636@1|root,COG4636@2|Bacteria,1G2JA@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_3323337_0	234267.Acid_1174	2.806e-230	735.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria	57723|Acidobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
YYD3_k127_3323842_1	1340493.JNIF01000003_gene4779	3.111e-76	264.0	COG0223@1|root,COG0223@2|Bacteria,3Y32C@57723|Acidobacteria	57723|Acidobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
YYD3_k127_3323842_2	204669.Acid345_4230	1.353e-28	124.0	COG2815@1|root,COG2815@2|Bacteria,3Y4UG@57723|Acidobacteria,2JJF0@204432|Acidobacteriia	204432|Acidobacteriia	S	PASTA domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA
YYD3_k127_3323842_0	156889.Mmc1_3649	3.21e-77	265.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
YYD3_k127_3337563_2	1038859.AXAU01000020_gene5398	1.322e-55	201.0	COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2TTXF@28211|Alphaproteobacteria,3JRB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YYD3_k127_3337563_4	247633.GP2143_17801	2.19e-23	106.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3337563_3	627192.SLG_09880	3.655e-24	112.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3337563_1	234267.Acid_2620	2.458e-205	661.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3337563_0	1267535.KB906767_gene3671	1.05e-248	788.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria,2JKK3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3346938_0	1123354.AUDR01000013_gene814	8.226e-101	331.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,1KRZJ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
YYD3_k127_3346938_1	1082931.KKY_123	9.25e-47	181.0	2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3346938_3	1033802.SSPSH_001859	6.819e-18	90.0	COG2062@1|root,COG2062@2|Bacteria,1PKQP@1224|Proteobacteria,1SDUE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
YYD3_k127_3354125_3	1245469.S58_28480	7.896e-43	161.0	2ART5@1|root,31H4G@2|Bacteria,1R86P@1224|Proteobacteria,2U0XF@28211|Alphaproteobacteria,3JV8H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3354125_0	398525.KB900701_gene7516	1.843e-139	458.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2TV6V@28211|Alphaproteobacteria,3JYN7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
YYD3_k127_3354125_1	1267534.KB906755_gene4117	1.372e-119	398.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_3354125_2	700598.Niako_2166	4.651e-50	189.0	COG0859@1|root,COG0859@2|Bacteria,4NIRT@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
YYD3_k127_3354125_5	335543.Sfum_0964	1.276e-14	76.0	2DMDG@1|root,32PV1@2|Bacteria,1MXEK@1224|Proteobacteria,42TGJ@68525|delta/epsilon subdivisions,2X7Q0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
YYD3_k127_3395484_1	234267.Acid_2629	9.719e-15	87.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3395484_0	234267.Acid_7841	1.563e-26	126.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3398054_1	234267.Acid_2620	4.955e-150	487.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3398054_0	1267535.KB906767_gene3671	1.293e-299	942.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria,2JKK3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3404305_0	869210.Marky_1927	1.869e-47	178.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD3_k127_3404305_3	869210.Marky_1927	9.949e-26	110.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD3_k127_3404305_1	869210.Marky_1927	8.438e-30	127.0	COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD3_k127_3404305_2	1123277.KB893174_gene6002	5.158e-26	108.0	COG0346@1|root,COG0346@2|Bacteria,4NRR7@976|Bacteroidetes,47QT0@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_3404592_0	234267.Acid_3838	2.18e-242	775.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_3404592_3	96561.Dole_2487	4.18e-05	49.0	COG3350@1|root,COG3350@2|Bacteria,1NGJJ@1224|Proteobacteria,42XCW@68525|delta/epsilon subdivisions,2WSVQ@28221|Deltaproteobacteria,2MMBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
YYD3_k127_3404592_1	1267533.KB906733_gene2863	5.145e-95	334.0	COG2984@1|root,COG4585@1|root,COG2984@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_3,PAS_9
YYD3_k127_3404592_2	448385.sce3280	6.915e-13	71.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2X7TS@28221|Deltaproteobacteria,2YXZZ@29|Myxococcales	28221|Deltaproteobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
YYD3_k127_3406492_1	448385.sce5615	1.374e-67	236.0	COG0580@1|root,COG0580@2|Bacteria,1QAD6@1224|Proteobacteria,434QA@68525|delta/epsilon subdivisions,2WZ1M@28221|Deltaproteobacteria,2Z14G@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	-	-	-	-	-	-	-	-	-	MIP
YYD3_k127_3406492_0	234267.Acid_5749	3.03e-172	566.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_3427441_7	1267533.KB906733_gene2798	5.421e-15	75.0	COG0267@1|root,COG0267@2|Bacteria,3Y5IT@57723|Acidobacteria,2JP2S@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
YYD3_k127_3427441_8	234267.Acid_6324	4.684e-08	57.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
YYD3_k127_3427441_3	1267535.KB906767_gene4464	8.883e-77	260.0	COG0250@1|root,COG0250@2|Bacteria,3Y3ZR@57723|Acidobacteria,2JHU8@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
YYD3_k127_3427441_4	1267535.KB906767_gene4465	5.675e-65	224.0	COG0080@1|root,COG0080@2|Bacteria,3Y7H1@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L11/L12	-	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
YYD3_k127_3427441_2	1121920.AUAU01000017_gene1254	1.927e-97	325.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
YYD3_k127_3427441_5	234267.Acid_5459	9.225e-50	183.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria	57723|Acidobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
YYD3_k127_3427441_6	1267535.KB906767_gene4468	6.457e-45	166.0	COG0222@1|root,COG0222@2|Bacteria,3Y50J@57723|Acidobacteria,2JJHE@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
YYD3_k127_3427441_0	234267.Acid_5457	0.0	2115.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
YYD3_k127_3427441_1	1047013.AQSP01000087_gene1646	0.0	1720.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
YYD3_k127_343105_0	234267.Acid_4800	0.0	1151.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
YYD3_k127_343105_7	234267.Acid_4799	1.026e-77	264.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
YYD3_k127_343105_6	1340493.JNIF01000004_gene925	4.647e-88	299.0	COG1305@1|root,COG1305@2|Bacteria,3Y3J9@57723|Acidobacteria	57723|Acidobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
YYD3_k127_343105_1	1340493.JNIF01000004_gene924	1.451e-262	835.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,3Y2FR@57723|Acidobacteria	57723|Acidobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
YYD3_k127_343105_3	234267.Acid_2498	7.997e-122	402.0	COG2307@1|root,COG2307@2|Bacteria,3Y3AM@57723|Acidobacteria	57723|Acidobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
YYD3_k127_343105_2	715226.ABI_12040	5.16e-191	611.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria,2KG7P@204458|Caulobacterales	204458|Caulobacterales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
YYD3_k127_343105_8	1340493.JNIF01000003_gene3836	7.846e-10	66.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_343105_5	379066.GAU_3854	7.806e-99	338.0	COG3174@1|root,COG3174@2|Bacteria,1ZUTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
YYD3_k127_343105_4	234267.Acid_4577	6.74e-101	339.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_3440484_0	234267.Acid_2823	0.0	1057.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
YYD3_k127_3440484_1	1267534.KB906754_gene3683	4.136e-132	428.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
YYD3_k127_3440484_2	429009.Adeg_0903	9.13e-84	285.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,24EJB@186801|Clostridia,42I6Q@68295|Thermoanaerobacterales	186801|Clostridia	I	Short-chain dehydrogenase reductase SDR	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD3_k127_3440484_3	1125863.JAFN01000001_gene311	1.489e-46	176.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
YYD3_k127_3440484_4	234267.Acid_4087	4.271e-31	129.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4,Peptidase_M10
YYD3_k127_3445996_0	671143.DAMO_2696	2.02e-158	511.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
YYD3_k127_3445996_4	234267.Acid_5312	7.153e-21	94.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
YYD3_k127_3445996_6	1125863.JAFN01000001_gene3090	2.613e-16	84.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	RNA polymerase-binding protein DksA	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YYD3_k127_3445996_2	1382359.JIAL01000001_gene2808	1.772e-67	243.0	COG0428@1|root,COG0428@2|Bacteria,3Y4A7@57723|Acidobacteria,2JJ1K@204432|Acidobacteriia	204432|Acidobacteriia	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
YYD3_k127_3445996_1	204669.Acid345_3198	2.261e-99	337.0	COG0012@1|root,COG0012@2|Bacteria,3Y3D9@57723|Acidobacteria,2JIPE@204432|Acidobacteriia	204432|Acidobacteriia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
YYD3_k127_3445996_3	278963.ATWD01000001_gene1968	6.163e-44	164.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
YYD3_k127_3445996_5	479434.Sthe_1998	6.889e-17	81.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YYD3_k127_3450292_5	639030.JHVA01000001_gene3306	1.663e-59	211.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria,2JHRS@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
YYD3_k127_3450292_7	278963.ATWD01000001_gene4283	3.07e-50	185.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria,2JJDW@204432|Acidobacteriia	204432|Acidobacteriia	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
YYD3_k127_3450292_6	204669.Acid345_0567	1.589e-57	206.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD3_k127_3450292_2	234267.Acid_7274	9.334e-151	489.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_3450292_11	671143.DAMO_0790	2.213e-13	73.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	PhdYeFM_antitox
YYD3_k127_3450292_9	671143.DAMO_0789	3.663e-32	130.0	COG3744@1|root,COG3744@2|Bacteria,2NRIX@2323|unclassified Bacteria	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_3450292_0	1379698.RBG1_1C00001G1165	5.695e-268	846.0	COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YYD3_k127_3450292_4	1254432.SCE1572_23620	1.836e-72	254.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
YYD3_k127_3450292_8	1122921.KB898201_gene3195	6.293e-37	153.0	COG0535@1|root,COG0535@2|Bacteria,1UXWS@1239|Firmicutes	1239|Firmicutes	C	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
YYD3_k127_3450292_3	234267.Acid_5820	2.935e-93	327.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
YYD3_k127_3450292_1	682795.AciX8_2124	1.267e-177	573.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria,2JKR9@204432|Acidobacteriia	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
YYD3_k127_3450292_10	1267535.KB906767_gene623	1.472e-13	81.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_3460575_3	204669.Acid345_0706	5.537e-20	100.0	COG2304@1|root,COG2304@2|Bacteria,3Y2QN@57723|Acidobacteria,2JI49@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3460575_0	1128421.JAGA01000002_gene557	3.732e-273	849.0	COG2866@1|root,COG2866@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YYD3_k127_3460575_4	1234364.AMSF01000088_gene2731	8.292e-12	73.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,1SCRY@1236|Gammaproteobacteria,1X8SI@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_3460575_2	1038866.KB902812_gene741	2.529e-79	273.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,3JVGF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
YYD3_k127_3460575_1	861299.J421_4070	2.249e-104	345.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
YYD3_k127_3462585_1	1128421.JAGA01000002_gene991	4.082e-114	377.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YYD3_k127_3462585_5	1540221.JQNI01000002_gene2414	5.551e-26	120.0	COG2823@1|root,COG2823@2|Bacteria,1WMQE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_3462585_0	1173027.Mic7113_5822	1.941e-183	580.0	COG1063@1|root,COG1063@2|Bacteria,1G26C@1117|Cyanobacteria,1H92J@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase GroES-like	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
YYD3_k127_3462585_2	211165.AJLN01000100_gene4217	1.893e-91	312.0	COG0300@1|root,COG0300@2|Bacteria,1G1AT@1117|Cyanobacteria,1JKU3@1189|Stigonemataceae	1117|Cyanobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD3_k127_3462585_3	1128421.JAGA01000001_gene2099	5.302e-45	170.0	COG5637@1|root,COG5637@2|Bacteria,2NRUC@2323|unclassified Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
YYD3_k127_3462585_6	700598.Niako_3128	8.68e-18	86.0	2EIK5@1|root,33CBF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3462585_4	1123508.JH636444_gene5540	4.257e-31	127.0	COG5592@1|root,COG5592@2|Bacteria,2J4HA@203682|Planctomycetes	2|Bacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD3_k127_3486350_0	1144275.COCOR_03545	2.643e-93	325.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2YUHW@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YYD3_k127_3486350_1	215803.DB30_0449	8.997e-60	214.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2X6DV@28221|Deltaproteobacteria,2YVCV@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
YYD3_k127_3486350_2	502025.Hoch_3128	1.258e-14	78.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2YVHM@29|Myxococcales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
YYD3_k127_3495402_0	240015.ACP_3307	8.278e-159	507.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
YYD3_k127_3495402_7	1121920.AUAU01000006_gene316	5.273e-15	87.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000006_gene316|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3495402_2	204669.Acid345_4328	1.592e-111	366.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria,2JI6S@204432|Acidobacteriia	204432|Acidobacteriia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
YYD3_k127_3495402_1	682795.AciX8_1188	4.676e-155	498.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
YYD3_k127_3495402_4	234267.Acid_1287	1.228e-53	203.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_3495402_5	1232410.KI421420_gene3159	1.761e-31	137.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YYD3_k127_3495402_3	795359.TOPB45_0159	1.047e-77	271.0	COG0564@1|root,COG0564@2|Bacteria,2GHCF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD3_k127_3495402_8	345341.KUTG_04140	8.406e-08	56.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3495402_6	1268239.PALB_25990	2.053e-31	128.0	2BZGP@1|root,32R51@2|Bacteria,1RJ1A@1224|Proteobacteria,1S6PS@1236|Gammaproteobacteria,2Q4Z6@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3504079_7	1499967.BAYZ01000136_gene42	2.376e-13	73.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YYD3_k127_3504079_0	1499967.BAYZ01000136_gene42	4.633e-164	538.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
YYD3_k127_3504079_1	1499967.BAYZ01000136_gene41	1.078e-125	412.0	COG4174@1|root,COG4174@2|Bacteria	2|Bacteria	P	ABC transporter (Permease)	oppB_2	-	-	ko:K02033,ko:K13894	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
YYD3_k127_3504079_3	1499967.BAYZ01000136_gene40	2.36e-119	396.0	COG4239@1|root,COG4239@2|Bacteria	2|Bacteria	P	microcin transport	yejE	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
YYD3_k127_3504079_2	1385511.N783_11305	1.787e-122	403.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,2Y9R6@289201|Pontibacillus	91061|Bacilli	EP	DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
YYD3_k127_3504079_4	1196324.A374_13255	8.484e-115	379.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YYD3_k127_3504079_5	1122139.KB907867_gene1149	1.654e-46	173.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria,1XKJG@135619|Oceanospirillales	135619|Oceanospirillales	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
YYD3_k127_3504079_6	1173026.Glo7428_0897	3.39e-39	154.0	COG0546@1|root,COG0546@2|Bacteria,1G6T7@1117|Cyanobacteria	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YYD3_k127_350886_3	269799.Gmet_2857	1.437e-38	150.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YYD3_k127_350886_4	1485545.JQLW01000009_gene127	5.179e-31	138.0	COG1055@1|root,COG2516@1|root,COG1055@2|Bacteria,COG2516@2|Bacteria,1QUC0@1224|Proteobacteria	1224|Proteobacteria	P	PFAM sodium	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
YYD3_k127_350886_0	204669.Acid345_1782	4.714e-316	985.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
YYD3_k127_350886_5	439235.Dalk_2504	6.53e-28	124.0	COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,1NWX3@1224|Proteobacteria,42URB@68525|delta/epsilon subdivisions,2WQ85@28221|Deltaproteobacteria,2MKYQ@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_350886_1	234267.Acid_4552	4.177e-67	236.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD3_k127_350886_2	234267.Acid_1804	6.844e-57	206.0	COG0571@1|root,COG0571@2|Bacteria,3Y4M2@57723|Acidobacteria	57723|Acidobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
YYD3_k127_350886_7	240015.ACP_3487	1.737e-06	56.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria,2JI5M@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
YYD3_k127_3520424_3	322710.Avin_33890	6.85e-50	186.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,1RPXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	yfjR	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
YYD3_k127_3520424_2	639283.Snov_0419	4.949e-75	262.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U255@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
YYD3_k127_3520424_0	234267.Acid_1304	1.751e-89	329.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_3520424_1	485918.Cpin_0501	9.277e-78	267.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1IQC4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
YYD3_k127_3524992_2	1297742.A176_06965	9.136e-30	121.0	COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,4358I@68525|delta/epsilon subdivisions,2WZJK@28221|Deltaproteobacteria,2Z29U@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
YYD3_k127_3524992_4	215803.DB30_2422	0.0005173	52.0	COG0750@1|root,COG4932@1|root,COG0750@2|Bacteria,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_3524992_1	671143.DAMO_1345	5.076e-69	248.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
YYD3_k127_3524992_0	1340493.JNIF01000003_gene2502	9.344e-106	359.0	COG0845@1|root,COG0845@2|Bacteria,3Y50Z@57723|Acidobacteria	57723|Acidobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD3_k127_3524992_3	366602.Caul_2395	2.128e-25	110.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,2KJ6C@204458|Caulobacterales	204458|Caulobacterales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3526546_1	671143.DAMO_0897	8.8e-55	199.0	COG0500@1|root,COG2226@2|Bacteria,2NPGE@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
YYD3_k127_3526546_0	338966.Ppro_0982	6.378e-63	229.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
YYD3_k127_3526546_2	648996.Theam_1640	1.508e-16	81.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	waaE	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glyco_transf_7C,Glycos_transf_2
YYD3_k127_3542580_6	404589.Anae109_0439	2.677e-40	156.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria,2Z2J1@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
YYD3_k127_3542580_5	335543.Sfum_2672	4.706e-45	177.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
YYD3_k127_3542580_2	382464.ABSI01000012_gene2146	5.443e-137	456.0	COG1593@1|root,COG1593@2|Bacteria	2|Bacteria	G	mannitol 2-dehydrogenase activity	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM,DctQ
YYD3_k127_3542580_0	1442599.JAAN01000020_gene2544	4.548e-201	642.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X39Z@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
YYD3_k127_3542580_7	1232410.KI421425_gene1566	1.664e-34	139.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3542580_1	269799.Gmet_1810	7.492e-163	539.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YYD3_k127_3542580_4	443143.GM18_3947	1.047e-95	324.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YYD3_k127_3542580_3	269799.Gmet_1812	6.315e-134	440.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
YYD3_k127_3542580_10	926569.ANT_24760	1.83e-13	77.0	2DSXF@1|root,33HTI@2|Bacteria,2G9HW@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD3_k127_3542580_9	552811.Dehly_1481	1.175e-14	81.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
YYD3_k127_3542580_8	880073.Calab_3539	4.899e-19	93.0	COG0589@1|root,COG0589@2|Bacteria,2NPUM@2323|unclassified Bacteria	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_3625364_2	670307.HYPDE_26878	4.304e-25	116.0	COG2197@1|root,COG2197@2|Bacteria,1NC01@1224|Proteobacteria,2URU3@28211|Alphaproteobacteria,3N8EV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3625364_0	246197.MXAN_3162	9.676e-264	820.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria,2YUMS@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
YYD3_k127_3625364_1	1042163.BRLA_c008750	1.018e-34	137.0	COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,26Z1H@186822|Paenibacillaceae	91061|Bacilli	S	membrane	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
YYD3_k127_3625364_3	234267.Acid_2557	3.628e-16	83.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_3627812_4	1185876.BN8_01219	0.0001175	47.0	COG1629@1|root,COG4771@2|Bacteria,4PN3U@976|Bacteroidetes,47Y97@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
YYD3_k127_3627812_2	234267.Acid_3837	6.519e-56	217.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_3627812_0	1123508.JH636441_gene3166	2.099e-70	254.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
YYD3_k127_3627812_1	861299.J421_5754	6.185e-60	221.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3627812_3	1038860.AXAP01000018_gene3108	4.776e-54	199.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_3647343_1	234267.Acid_2488	9.144e-29	122.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_3647343_0	1485545.JQLW01000005_gene994	5.761e-97	334.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria	1224|Proteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3,2.8.4.5	ko:K06168,ko:K18707	-	-	R10645,R10646,R10647,R10649	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YYD3_k127_3647343_2	448385.sce1473	2.138e-21	99.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
YYD3_k127_3647343_3	1442599.JAAN01000020_gene2607	4.489e-20	96.0	COG3453@1|root,COG3453@2|Bacteria,1N919@1224|Proteobacteria,1SEMT@1236|Gammaproteobacteria,1X8A2@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
YYD3_k127_3648013_0	1382359.JIAL01000001_gene2820	1.074e-35	156.0	2EXAB@1|root,33QKZ@2|Bacteria,3Y6WS@57723|Acidobacteria,2JMCR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3648013_1	344747.PM8797T_05510	2.446e-18	87.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
YYD3_k127_3649367_0	1267535.KB906767_gene3728	2.241e-149	492.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_3649367_1	382464.ABSI01000010_gene3212	1.37e-97	329.0	COG0330@1|root,COG0330@2|Bacteria,46USS@74201|Verrucomicrobia,2IVC2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
YYD3_k127_3649367_4	1111069.TCCBUS3UF1_22360	5.293e-11	64.0	COG4877@1|root,COG4877@2|Bacteria,1WKMS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
YYD3_k127_3649367_3	1123242.JH636435_gene1809	1.718e-32	132.0	2E13H@1|root,32WIX@2|Bacteria,2J0HQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3649367_2	768671.ThimaDRAFT_4798	6.13e-68	240.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria,1WZ6R@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3655531_0	1268622.AVS7_02582	5.534e-101	333.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AA92@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	gspE1	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
YYD3_k127_3655531_2	1267534.KB906755_gene4692	7.496e-51	202.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3655531_1	1267534.KB906755_gene4691	1.438e-68	243.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_3655531_3	1047013.AQSP01000091_gene656	3.728e-09	63.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TPR_6
YYD3_k127_3662537_2	497964.CfE428DRAFT_2824	2.628e-07	55.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3662537_0	344747.PM8797T_32255	2.455e-104	345.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_3662537_1	1158756.AQXQ01000011_gene867	2.018e-28	125.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,1S150@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
YYD3_k127_3700522_1	234267.Acid_2177	3.051e-58	221.0	COG4932@1|root,COG4932@2|Bacteria,3Y3KQ@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3700522_0	84531.JMTZ01000010_gene3183	1.047e-64	252.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S0D5@1236|Gammaproteobacteria,1X4Y2@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
YYD3_k127_3701270_1	118168.MC7420_4357	2.126e-107	362.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_9
YYD3_k127_3701270_2	395019.Bmul_0906	7.938e-05	55.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2WFD9@28216|Betaproteobacteria,1KI0Q@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras,PCMT
YYD3_k127_3701270_0	1123508.JH636449_gene7450	4.915e-182	579.0	COG0205@1|root,COG0205@2|Bacteria,2IYE1@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	-	-	-	-	-	-	-	-	-	-	PFK
YYD3_k127_3706356_7	1245469.S58_18170	8.779e-05	49.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,3JTAE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	MA20_01040	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YYD3_k127_3706356_4	1123242.JH636435_gene2238	1.961e-48	184.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_3706356_0	1379270.AUXF01000001_gene2303	3.51e-139	469.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
YYD3_k127_3706356_5	234267.Acid_6437	4.172e-35	147.0	COG4249@1|root,COG4249@2|Bacteria,3Y6DQ@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
YYD3_k127_3706356_2	1267534.KB906756_gene98	1.773e-121	422.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y6C4@57723|Acidobacteria	57723|Acidobacteria	E	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
YYD3_k127_3706356_1	234267.Acid_6435	1.678e-125	410.0	COG0714@1|root,COG0714@2|Bacteria,3Y3BH@57723|Acidobacteria	57723|Acidobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD3_k127_3706356_3	1340493.JNIF01000003_gene4792	1.663e-84	289.0	COG1721@1|root,COG1721@2|Bacteria,3Y5XW@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YYD3_k127_3706356_6	1396141.BATP01000007_gene5563	3.662e-08	64.0	COG2304@1|root,COG3210@1|root,COG2304@2|Bacteria,COG3210@2|Bacteria,46UJG@74201|Verrucomicrobia,2IVBI@203494|Verrucomicrobiae	2|Bacteria	U	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	SLH
YYD3_k127_3706397_3	986075.CathTA2_2096	0.0002055	53.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
YYD3_k127_3706397_0	204669.Acid345_1390	2.171e-139	453.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
YYD3_k127_3706397_1	204669.Acid345_1393	2.523e-116	401.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	204432|Acidobacteriia	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
YYD3_k127_3706397_2	234267.Acid_7351	2.482e-66	238.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_371108_1	316067.Geob_1840	7.625e-111	364.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
YYD3_k127_371108_0	1237149.C900_00071	0.0	1020.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
YYD3_k127_371108_2	1237149.C900_00072	2.279e-80	274.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
YYD3_k127_3712672_2	1229172.JQFA01000005_gene112	7.227e-40	152.0	COG4339@1|root,COG4339@2|Bacteria,1G5Q9@1117|Cyanobacteria,1HCCR@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG4339 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3712672_1	292459.STH2424	7.183e-53	198.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
YYD3_k127_3712672_0	886293.Sinac_0207	2.165e-155	499.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
YYD3_k127_372037_1	1056820.KB900640_gene290	2.859e-89	309.0	COG3794@1|root,COG3794@2|Bacteria,1R29B@1224|Proteobacteria	1224|Proteobacteria	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
YYD3_k127_372037_0	743722.Sph21_4223	3.603e-105	347.0	COG0457@1|root,COG0457@2|Bacteria,4PN62@976|Bacteroidetes,1IQEB@117747|Sphingobacteriia	976|Bacteroidetes	S	Rifampin ADP-ribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Arr-ms
YYD3_k127_372037_3	234267.Acid_0687	9.613e-05	48.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
YYD3_k127_372037_2	497964.CfE428DRAFT_4864	9.04e-29	119.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3720584_5	1267535.KB906767_gene4650	1.544e-25	106.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_3720584_0	234267.Acid_1824	1.241e-105	375.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_3720584_3	502025.Hoch_0349	3.019e-39	155.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.11,5.4.2.12	ko:K01834,ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YYD3_k127_3720584_2	869209.Tresu_1797	3.057e-54	205.0	COG0564@1|root,COG0564@2|Bacteria,2J5SJ@203691|Spirochaetes	203691|Spirochaetes	J	S4 RNA-binding domain	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
YYD3_k127_3720584_1	1444711.CCJF01000005_gene357	4.509e-55	202.0	2C3WA@1|root,2Z8P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
YYD3_k127_3720584_4	1382306.JNIM01000001_gene1060	4.632e-37	150.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YYD3_k127_3720584_6	234267.Acid_6567	7.83e-21	93.0	COG0826@1|root,COG0826@2|Bacteria,3Y7M5@57723|Acidobacteria	57723|Acidobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
YYD3_k127_3728654_10	1396418.BATQ01000107_gene5411	0.0002295	48.0	COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YYD3_k127_3728654_4	1157490.EL26_08070	4.241e-54	193.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,27A2U@186823|Alicyclobacillaceae	91061|Bacilli	M	Large-conductance mechanosensitive channel, MscL	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
YYD3_k127_3728654_8	1158338.JNLJ01000001_gene230	1.599e-11	74.0	COG3137@1|root,COG3137@2|Bacteria,2G4AG@200783|Aquificae	200783|Aquificae	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
YYD3_k127_3728654_0	1121920.AUAU01000020_gene2550	1.233e-211	670.0	COG0433@1|root,COG0433@2|Bacteria,3Y69X@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF853
YYD3_k127_3728654_7	404589.Anae109_3528	7.273e-16	83.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2YVIX@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
YYD3_k127_3728654_1	1123354.AUDR01000015_gene349	1.249e-163	527.0	COG1488@1|root,COG1488@2|Bacteria,1PNWY@1224|Proteobacteria,2W9DN@28216|Betaproteobacteria,1KS4Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	-	-	-	-	-	-	-	-	-	-	NAPRTase
YYD3_k127_3728654_2	926550.CLDAP_36390	4.506e-135	438.0	COG1335@1|root,COG1335@2|Bacteria,2G8KH@200795|Chloroflexi	200795|Chloroflexi	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3728654_3	247633.GP2143_18121	6.07e-82	280.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3728654_5	247633.GP2143_18126	3.086e-33	142.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3728654_6	247633.GP2143_18131	1.778e-22	104.0	2C42J@1|root,3359Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3728654_9	876269.ARWA01000001_gene157	7.808e-09	61.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,dCache_1
YYD3_k127_3733970_1	187272.Mlg_0096	1.513e-40	153.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1WW1M@135613|Chromatiales	135613|Chromatiales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
YYD3_k127_3733970_0	243090.RB617	1.268e-87	311.0	COG2319@1|root,COG2319@2|Bacteria,2IXSY@203682|Planctomycetes	203682|Planctomycetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
YYD3_k127_3745790_24	1267211.KI669560_gene1684	6.358e-26	112.0	2DTGN@1|root,33K97@2|Bacteria,4NZIF@976|Bacteroidetes,1IU43@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3745790_6	1121015.N789_00820	3.768e-111	364.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
YYD3_k127_3745790_21	266117.Rxyl_0279	3.655e-50	184.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
YYD3_k127_3745790_23	240015.ACP_0949	6.016e-27	118.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_3745790_5	868595.Desca_0762	5.797e-118	389.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,2609J@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
YYD3_k127_3745790_3	330214.NIDE2870	2.407e-146	470.0	COG0451@1|root,COG0451@2|Bacteria,3J0BW@40117|Nitrospirae	40117|Nitrospirae	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_3745790_1	1297742.A176_03413	2.407e-169	541.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
YYD3_k127_3745790_10	240015.ACP_0929	6.742e-97	321.0	COG2057@1|root,COG2057@2|Bacteria,3Y3EC@57723|Acidobacteria,2JIV4@204432|Acidobacteriia	204432|Acidobacteriia	I	Coenzyme A transferase	-	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
YYD3_k127_3745790_7	204669.Acid345_1163	3.938e-104	342.0	COG1788@1|root,COG1788@2|Bacteria,3Y3R1@57723|Acidobacteria,2JISA@204432|Acidobacteriia	204432|Acidobacteriia	I	Coenzyme A transferase	-	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
YYD3_k127_3745790_22	1089550.ATTH01000001_gene1189	1.13e-42	169.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1FJ4K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
YYD3_k127_3745790_25	316067.Geob_2840	5.264e-19	89.0	COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
YYD3_k127_3745790_11	1267535.KB906767_gene284	1.614e-83	284.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
YYD3_k127_3745790_0	240015.ACP_1770	4.124e-177	561.0	COG0133@1|root,COG0133@2|Bacteria,3Y45B@57723|Acidobacteria,2JIVM@204432|Acidobacteriia	204432|Acidobacteriia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_3745790_19	398767.Glov_1212	1.137e-56	205.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
YYD3_k127_3745790_18	1449050.JNLE01000003_gene2943	9.815e-58	212.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,36EKM@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
YYD3_k127_3745790_9	204669.Acid345_3885	4.062e-97	328.0	COG0547@1|root,COG0547@2|Bacteria,3Y3YF@57723|Acidobacteria,2JIGH@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
YYD3_k127_3745790_12	1408254.T458_25155	6.881e-79	267.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01664	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	iYO844.BSU00750	GATase
YYD3_k127_3745790_2	204669.Acid345_4120	2.18e-162	525.0	COG0147@1|root,COG0147@2|Bacteria,3Y2UX@57723|Acidobacteria,2JIMP@204432|Acidobacteriia	204432|Acidobacteriia	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
YYD3_k127_3745790_17	1341151.ASZU01000008_gene1602	5.197e-65	229.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,27BTU@186824|Thermoactinomycetaceae	91061|Bacilli	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
YYD3_k127_3745790_8	1123392.AQWL01000008_gene1196	1.026e-102	340.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1KS6H@119069|Hydrogenophilales	119069|Hydrogenophilales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YYD3_k127_3745790_14	1269813.ATUL01000004_gene2225	6.276e-71	247.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1WXHX@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
YYD3_k127_3745790_16	404380.Gbem_3702	2.255e-67	234.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,43TF4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YYD3_k127_3745790_15	1122137.AQXF01000001_gene3348	1.63e-68	238.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9,3.1.3.15,4.2.1.19	ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03013,R03243,R03457	RC00006,RC00017,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	IGPD
YYD3_k127_3745790_13	370438.PTH_2537	7.317e-72	255.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,2606W@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_3745790_4	1244869.H261_11694	1.676e-118	394.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,2JPGF@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
YYD3_k127_3745790_20	697281.Mahau_0264	3.485e-55	200.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,42G66@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
YYD3_k127_3745790_26	1123313.ATUT01000002_gene287	0.0001124	46.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,3VPA8@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
YYD3_k127_3752149_1	309799.DICTH_0629	2.698e-31	127.0	COG1847@1|root,COG3854@1|root,COG1847@2|Bacteria,COG3854@2|Bacteria	2|Bacteria	S	ATPases associated with a variety of cellular activities	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
YYD3_k127_3752149_0	671143.DAMO_2996	3.244e-57	219.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_3752149_2	401053.AciPR4_2697	2.262e-25	122.0	COG0823@1|root,COG0823@2|Bacteria,3Y4FU@57723|Acidobacteria,2JJ6C@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD3_k127_3752149_3	1158294.JOMI01000003_gene2707	0.0001242	44.0	COG1166@1|root,COG1166@2|Bacteria,4PKX0@976|Bacteroidetes,2FMN2@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YYD3_k127_3757961_2	1340493.JNIF01000004_gene437	1.933e-78	270.0	COG0101@1|root,COG0101@2|Bacteria,3Y833@57723|Acidobacteria	57723|Acidobacteria	J	tRNA pseudouridine synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
YYD3_k127_3757961_0	379066.GAU_2821	1.031e-82	288.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3757961_1	379066.GAU_2821	7.543e-79	278.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3757961_3	909663.KI867150_gene2720	1.445e-66	238.0	COG0535@1|root,COG0535@2|Bacteria,1Q6NI@1224|Proteobacteria,433FI@68525|delta/epsilon subdivisions,2WXJT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_3767055_2	278963.ATWD01000002_gene367	2.08e-52	195.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria,2JI16@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_3767055_0	306281.AJLK01000103_gene3380	4.172e-168	537.0	COG0436@1|root,COG0436@2|Bacteria,1G202@1117|Cyanobacteria,1JKEM@1189|Stigonemataceae	1117|Cyanobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_3767055_3	1267535.KB906767_gene4740	2.942e-17	95.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_3767055_1	234267.Acid_7841	1.156e-154	538.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3767055_4	401053.AciPR4_1175	3.378e-11	75.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_3777975_1	926560.KE387023_gene3028	4.612e-30	138.0	2DVHC@1|root,33VWJ@2|Bacteria,1WMN4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3777975_4	1340493.JNIF01000003_gene2146	4.849e-05	48.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_3777975_5	1089550.ATTH01000001_gene2237	0.0002896	45.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_3777975_3	1340493.JNIF01000003_gene4208	9.442e-09	61.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_3777975_0	1254432.SCE1572_28790	8.603e-58	209.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,43E08@68525|delta/epsilon subdivisions,2WZBV@28221|Deltaproteobacteria,2Z1SW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3777975_2	357808.RoseRS_0439	2.07e-19	91.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YYD3_k127_379690_0	243090.RB7928	2.04e-66	254.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
YYD3_k127_3802635_2	1123073.KB899242_gene952	1.15e-53	204.0	COG0666@1|root,COG0666@2|Bacteria,1P877@1224|Proteobacteria,1T8UK@1236|Gammaproteobacteria,1XB99@135614|Xanthomonadales	135614|Xanthomonadales	S	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
YYD3_k127_3802635_3	234267.Acid_1337	2.663e-40	162.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
YYD3_k127_3802635_4	1210884.HG799463_gene9962	4.538e-15	82.0	2CK1C@1|root,32SJA@2|Bacteria,2J05T@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3802635_5	234267.Acid_7691	1.101e-09	65.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_3802635_0	234267.Acid_5615	2.46e-136	445.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
YYD3_k127_3802635_1	1173028.ANKO01000052_gene1669	3.398e-93	312.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1HA99@1150|Oscillatoriales	1117|Cyanobacteria	E	SMART ATPase, AAA type, core	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
YYD3_k127_3804005_10	234267.Acid_2701	7.781e-31	134.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_3804005_12	1123386.AUIW01000009_gene1744	2.268e-25	117.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1WJBW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_3804005_11	335543.Sfum_0590	3.502e-27	120.0	2BQW2@1|root,32JT0@2|Bacteria,1QNFB@1224|Proteobacteria,432XH@68525|delta/epsilon subdivisions,2WYDA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3804005_13	1370121.AUWS01000037_gene4639	2.371e-25	109.0	COG2149@1|root,COG2149@2|Bacteria,2ISPE@201174|Actinobacteria,23AVT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF202
YYD3_k127_3804005_5	639030.JHVA01000001_gene3181	2.031e-51	192.0	2C6A3@1|root,34625@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3804005_15	1144305.PMI02_00736	5.563e-06	50.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase A	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
YYD3_k127_3804005_3	1379270.AUXF01000005_gene644	1.441e-78	268.0	28NKC@1|root,2ZBM7@2|Bacteria,1ZUHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3804005_9	1267534.KB906754_gene3089	1.432e-35	153.0	COG3064@1|root,COG3064@2|Bacteria,3Y7SB@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
YYD3_k127_3804005_2	909663.KI867150_gene2891	2.354e-82	283.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
YYD3_k127_3804005_6	1042377.AFPJ01000043_gene881	7.947e-49	181.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
YYD3_k127_3804005_14	1366050.N234_06335	1.102e-22	105.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K7R1@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
YYD3_k127_3804005_0	1234664.AMRO01000050_gene367	4.654e-167	542.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,1WEFD@129337|Geobacillus	91061|Bacilli	E	Oligoendopeptidase F	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
YYD3_k127_3804005_7	234267.Acid_7037	1.337e-47	181.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
YYD3_k127_3804005_1	278963.ATWD01000001_gene1201	1.694e-89	310.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	-	-	-	-	-	-	-	-	-	IMS
YYD3_k127_3804005_4	1267534.KB906758_gene2522	3.556e-55	203.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria,2JKQG@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
YYD3_k127_3804755_1	246197.MXAN_6138	2.345e-98	321.0	COG0262@1|root,COG0262@2|Bacteria,1QH1Q@1224|Proteobacteria,4341U@68525|delta/epsilon subdivisions,2X4QE@28221|Deltaproteobacteria,2YZE6@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YYD3_k127_3804755_6	760192.Halhy_5892	2.439e-18	96.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
YYD3_k127_3804755_3	234267.Acid_7883	3.965e-94	326.0	COG1432@1|root,COG1432@2|Bacteria,3Y64C@57723|Acidobacteria	57723|Acidobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
YYD3_k127_3804755_0	204669.Acid345_2858	1.073e-179	594.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	2|Bacteria	I	Phosphate acyltransferases	fadD	-	2.3.1.51,6.2.1.3	ko:K00655,ko:K01897	ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00089	R01280,R02241,R09381	RC00004,RC00014,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
YYD3_k127_3804755_2	1047013.AQSP01000142_gene195	1.336e-96	328.0	COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
YYD3_k127_3804755_4	1280941.HY2_10245	9.036e-31	125.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,43YGP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Flavin_Reduct,Hydrolase_4
YYD3_k127_3826488_2	886293.Sinac_1154	2.067e-38	147.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_3826488_3	1298867.AUES01000010_gene5873	1.28e-30	132.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,3JUHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3826488_1	1340493.JNIF01000003_gene3476	1.686e-47	190.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
YYD3_k127_3826488_0	861299.J421_5754	1.986e-64	233.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3831445_0	867903.ThesuDRAFT_00006	1.395e-102	343.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3WCNJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YYD3_k127_3831445_1	648996.Theam_0382	7.493e-54	194.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
YYD3_k127_3831445_2	234267.Acid_7914	1.058e-32	142.0	COG0457@1|root,COG0457@2|Bacteria,3Y7TN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3831445_3	1128421.JAGA01000001_gene2435	3.713e-21	98.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
YYD3_k127_3838779_0	452637.Oter_1817	7.443e-215	679.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
YYD3_k127_3838779_4	945713.IALB_0236	1.063e-06	55.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	ugl	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
YYD3_k127_3838779_3	1254432.SCE1572_01100	7.63e-07	55.0	COG2405@1|root,COG2405@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3838779_2	1340493.JNIF01000003_gene3280	9.896e-39	150.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_3838779_1	1183438.GKIL_4354	1.872e-93	325.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_3844668_6	344747.PM8797T_06150	4.909e-23	104.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3844668_3	204669.Acid345_0838	1.039e-32	138.0	COG2208@1|root,COG2208@2|Bacteria,3Y6VQ@57723|Acidobacteria,2JKZZ@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
YYD3_k127_3844668_1	1500259.JQLD01000010_gene4885	3.058e-61	222.0	COG4122@1|root,COG4122@2|Bacteria,1N57D@1224|Proteobacteria,2U6NA@28211|Alphaproteobacteria,4BBI5@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1442)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
YYD3_k127_3844668_0	1089547.KB913013_gene4045	7.235e-63	220.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,47Q00@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_3844668_5	234267.Acid_2323	6.123e-30	130.0	COG1040@1|root,COG1040@2|Bacteria,3Y5KW@57723|Acidobacteria	57723|Acidobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	DZR,PLDc_N
YYD3_k127_3844668_2	234267.Acid_2321	1.194e-46	177.0	COG1595@1|root,COG1595@2|Bacteria,3Y45G@57723|Acidobacteria	2|Bacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
YYD3_k127_3844668_4	644076.SCH4B_4475	5.534e-30	121.0	COG0454@1|root,COG0454@2|Bacteria,1N1AI@1224|Proteobacteria,2U9PT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
YYD3_k127_3845060_3	1340493.JNIF01000003_gene3848	3.841e-52	188.0	COG0524@1|root,COG0524@2|Bacteria,3Y6VV@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YYD3_k127_3845060_0	234267.Acid_2666	0.0	1163.0	COG3661@1|root,COG3661@2|Bacteria,3Y2TM@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
YYD3_k127_3845060_2	1267535.KB906767_gene2960	6.386e-105	347.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria,2JHIF@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD3_k127_3845060_1	234267.Acid_2667	2.648e-234	728.0	COG4948@1|root,COG4948@2|Bacteria,3Y4P2@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YYD3_k127_3855332_3	1156937.MFUM_700141	4.447e-07	61.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,37G9U@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
YYD3_k127_3855332_5	215803.DB30_6133	3.836e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1PEIM@1224|Proteobacteria,4341Z@68525|delta/epsilon subdivisions,2X4QS@28221|Deltaproteobacteria,2YZEK@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
YYD3_k127_3855332_4	383372.Rcas_0215	5.247e-06	58.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2G9QS@200795|Chloroflexi	200795|Chloroflexi	T	SMART RNA-processing protein HAT helix repeating-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_8
YYD3_k127_3855332_2	326427.Cagg_1608	1.244e-23	111.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi,375R5@32061|Chloroflexia	32061|Chloroflexia	S	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
YYD3_k127_3855332_0	1123299.AUKZ01000009_gene1499	1.938e-31	125.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4HM6R@91061|Bacilli	91061|Bacilli	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
YYD3_k127_3855332_1	349161.Dred_1305	2.7e-24	109.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,260WN@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM acetaldehyde dehydrogenase (acetylating)	-	-	1.2.1.10	ko:K00132	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD3_k127_3862540_2	234267.Acid_6308	4.15e-34	144.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_3862540_0	204669.Acid345_3921	5.752e-198	630.0	COG0146@1|root,COG0146@2|Bacteria,3Y6W2@57723|Acidobacteria,2JKCE@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
YYD3_k127_3862540_1	760142.Hipma_0529	1.969e-120	399.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2M6Q5@213113|Desulfurellales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
YYD3_k127_3874615_0	697329.Rumal_0984	3.059e-114	380.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
YYD3_k127_3874615_1	1267535.KB906767_gene4827	8.79e-48	178.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria,2JJ3X@204432|Acidobacteriia	204432|Acidobacteriia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
YYD3_k127_3887260_0	1121472.AQWN01000012_gene967	2.341e-96	336.0	COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,2622J@186807|Peptococcaceae	186801|Clostridia	L	type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	HNH,Helicase_C,ResIII
YYD3_k127_3887260_1	158500.BV97_01286	5.455e-69	246.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,2KATS@204457|Sphingomonadales	204457|Sphingomonadales	S	Beta-lactamase superfamily domain	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_3887260_2	247633.GP2143_17791	1.609e-65	233.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3891359_4	1340493.JNIF01000003_gene3955	4.049e-37	143.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
YYD3_k127_3891359_3	1242864.D187_004972	1.408e-37	154.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions,2WSUD@28221|Deltaproteobacteria,2YV76@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
YYD3_k127_3891359_1	1382359.JIAL01000001_gene2623	1.985e-72	254.0	COG0842@1|root,COG0842@2|Bacteria,3Y2S4@57723|Acidobacteria,2JISC@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YYD3_k127_3891359_0	1382359.JIAL01000001_gene2624	2.887e-106	353.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_3891359_2	234267.Acid_4382	3.093e-44	165.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
YYD3_k127_3903155_0	671143.DAMO_1865	3.597e-218	692.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
YYD3_k127_3903155_1	1463820.JOGW01000008_gene1674	3.887e-47	175.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
YYD3_k127_3903155_2	1340493.JNIF01000004_gene600	2.044e-21	98.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
YYD3_k127_3906785_0	272123.Anacy_2037	1.381e-25	124.0	COG4995@1|root,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7
YYD3_k127_3906785_1	1267535.KB906767_gene942	2.92e-25	109.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_3914690_1	215803.DB30_4777	1.424e-103	339.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42UHA@68525|delta/epsilon subdivisions,2WQA0@28221|Deltaproteobacteria,2YUHZ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YYD3_k127_3914690_3	1303518.CCALI_00500	9.893e-07	57.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	wrbA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
YYD3_k127_3914690_2	251229.Chro_2996	8.889e-86	289.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,3VJ25@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
YYD3_k127_3914690_0	196367.JNFG01000008_gene6597	4.017e-137	442.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2VRSG@28216|Betaproteobacteria,1K889@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_3916432_3	420324.KI912004_gene8563	1.482e-12	70.0	COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,2UEEU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YYD3_k127_3916432_0	497964.CfE428DRAFT_5917	1.724e-256	815.0	COG0553@1|root,COG0553@2|Bacteria,46S56@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase recycling family C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,RapA_C,SNF2_N
YYD3_k127_3916432_2	1163409.UUA_06724	2.284e-95	320.0	COG0697@1|root,COG0697@2|Bacteria,1N4MD@1224|Proteobacteria,1SZQ5@1236|Gammaproteobacteria,1X4YA@135614|Xanthomonadales	135614|Xanthomonadales	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
YYD3_k127_3916432_1	237368.SCABRO_03612	1.524e-113	373.0	COG0656@1|root,COG0656@2|Bacteria,2IWVI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
YYD3_k127_3916465_13	420324.KI912044_gene3909	1.863e-50	192.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2TVYD@28211|Alphaproteobacteria,1JZHG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Histidine kinase	degS	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
YYD3_k127_3916465_10	298654.FraEuI1c_1580	1.464e-84	284.0	28K2Y@1|root,2Z9S8@2|Bacteria,2I94F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3916465_2	479432.Sros_4534	6.493e-172	544.0	28IJ3@1|root,2Z8K2@2|Bacteria,2H0MB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3916465_0	1242864.D187_007007	2.064e-216	683.0	COG2837@1|root,COG2837@2|Bacteria,1MXKF@1224|Proteobacteria,43801@68525|delta/epsilon subdivisions,2X39Y@28221|Deltaproteobacteria,2YV1P@29|Myxococcales	28221|Deltaproteobacteria	C	peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Dyp_perox
YYD3_k127_3916465_7	204669.Acid345_1376	1.692e-112	372.0	COG4313@1|root,COG4313@2|Bacteria,3Y3E2@57723|Acidobacteria,2JKNK@204432|Acidobacteriia	204432|Acidobacteriia	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YYD3_k127_3916465_1	1380386.JIAW01000005_gene1769	2.525e-194	616.0	COG1249@1|root,COG1249@2|Bacteria,2IDQR@201174|Actinobacteria,23CBU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD3_k127_3916465_9	1121920.AUAU01000004_gene789	2.175e-104	351.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_3916465_4	234267.Acid_0353	9.266e-161	512.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
YYD3_k127_3916465_8	234267.Acid_0352	3.24e-111	378.0	COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
YYD3_k127_3916465_6	1210884.HG799462_gene8074	1.963e-136	442.0	COG1090@1|root,COG1090@2|Bacteria,2IYWK@203682|Planctomycetes	203682|Planctomycetes	S	nucleoside-diphosphate sugar epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
YYD3_k127_3916465_14	1396418.BATQ01000168_gene1799	9.257e-29	120.0	COG3011@1|root,COG3011@2|Bacteria,46WSM@74201|Verrucomicrobia,2IUZ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
YYD3_k127_3916465_11	246197.MXAN_1654	6.049e-69	241.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
YYD3_k127_3916465_3	1047013.AQSP01000107_gene2089	1.6e-164	583.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
YYD3_k127_3916465_12	1054213.HMPREF9946_03238	9.285e-62	236.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2TVYD@28211|Alphaproteobacteria,2JZ0H@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
YYD3_k127_3916465_15	243233.MCA0985	5.834e-21	108.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XFYJ@135618|Methylococcales	135618|Methylococcales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_4,PAS_9
YYD3_k127_3916465_5	1267535.KB906767_gene3664	3.01e-155	507.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_3916465_16	504472.Slin_6210	8.886e-08	58.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6B@976|Bacteroidetes,47MFW@768503|Cytophagia	976|Bacteroidetes	C	PFAM PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
YYD3_k127_3917838_4	56780.SYN_00826	1.181e-06	53.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,NodS
YYD3_k127_3917838_0	56780.SYN_00827	1.086e-158	510.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2MQTT@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_3917838_3	1537715.JQFJ01000001_gene2707	1.261e-40	154.0	2BWTW@1|root,315N7@2|Bacteria,1RABY@1224|Proteobacteria,2U5VH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3917838_2	1041142.ATTP01000010_gene1485	1.439e-64	238.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,2U16K@28211|Alphaproteobacteria,4BDSQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
YYD3_k127_3917838_1	483219.LILAB_18860	2.575e-73	250.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42UHA@68525|delta/epsilon subdivisions,2WQA0@28221|Deltaproteobacteria,2YUHZ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
YYD3_k127_3928717_0	452637.Oter_1642	1.067e-104	344.0	COG0563@1|root,COG0563@2|Bacteria,46UF6@74201|Verrucomicrobia,3K7G4@414999|Opitutae	414999|Opitutae	F	adenylate kinase	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
YYD3_k127_3928717_1	99598.Cal7507_1181	1.405e-67	239.0	COG3393@1|root,COG3393@2|Bacteria,1G551@1117|Cyanobacteria,1HKPV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Acetyltransferase (GNAT) family	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,FR47
YYD3_k127_3928717_2	639030.JHVA01000001_gene3612	2.74e-21	106.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
YYD3_k127_3928717_3	469595.CSAG_00209	8.04e-10	61.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,3WYVI@544|Citrobacter	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
YYD3_k127_3931819_1	1122604.JONR01000010_gene3984	1.092e-84	293.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1X4YB@135614|Xanthomonadales	135614|Xanthomonadales	V	Inner membrane protein involved in colicin E2 resistance	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
YYD3_k127_3931819_0	448385.sce0675	1.033e-103	351.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,437UU@68525|delta/epsilon subdivisions,2WYPC@28221|Deltaproteobacteria,2YU77@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
YYD3_k127_3937454_3	335543.Sfum_0537	2.474e-25	119.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MQJZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
YYD3_k127_3937454_1	429009.Adeg_0968	7.756e-101	344.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
YYD3_k127_3937454_2	497964.CfE428DRAFT_0598	1.732e-82	278.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	PFAM glutamine amidotransferase class-I	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
YYD3_k127_3937454_0	700598.Niako_0762	9.192e-116	378.0	COG5297@1|root,COG5297@2|Bacteria,4PKPX@976|Bacteroidetes,1IV41@117747|Sphingobacteriia	976|Bacteroidetes	G	Fg-gap repeat	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
YYD3_k127_3937454_4	700598.Niako_3643	1.335e-20	91.0	COG5297@1|root,COG5297@2|Bacteria,4PKPX@976|Bacteroidetes,1IV41@117747|Sphingobacteriia	976|Bacteroidetes	G	Fg-gap repeat	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
YYD3_k127_3941633_0	1340493.JNIF01000003_gene1952	9.529e-184	600.0	COG0841@1|root,COG0841@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
YYD3_k127_3941633_11	1120985.AUMI01000014_gene1192	5.216e-33	144.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4H2CU@909932|Negativicutes	909932|Negativicutes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
YYD3_k127_3941633_9	1437824.BN940_08521	6.82e-60	219.0	COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,2VMCM@28216|Betaproteobacteria,3T4CS@506|Alcaligenaceae	28216|Betaproteobacteria	I	Domain of unknown function (DUF1932)	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	DUF1932,NAD_binding_2
YYD3_k127_3941633_2	1230476.C207_00196	1.928e-172	545.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,2TVM0@28211|Alphaproteobacteria,3JW6H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	ligJ	-	4.1.1.45,4.2.1.83	ko:K03392,ko:K10220	ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120	M00038	R04323,R04478	RC00498,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
YYD3_k127_3941633_6	1123023.JIAI01000013_gene4027	1.317e-98	334.0	COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively	ligB	-	1.13.11.57,1.13.11.8	ko:K04099,ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA,LigB
YYD3_k127_3941633_7	234267.Acid_6636	1.536e-92	309.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	ligK	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
YYD3_k127_3941633_3	1123399.AQVE01000005_gene962	1.117e-146	471.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dehydrogenases and related proteins	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_3941633_8	702113.PP1Y_AT31210	5.428e-68	237.0	COG0684@1|root,COG0684@2|Bacteria,1QSHP@1224|Proteobacteria,2U948@28211|Alphaproteobacteria,2K5JG@204457|Sphingomonadales	204457|Sphingomonadales	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
YYD3_k127_3941633_5	1340493.JNIF01000003_gene2181	1.751e-100	345.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,OMP_b-brl
YYD3_k127_3941633_1	1396418.BATQ01000051_gene63	2.389e-173	556.0	COG0715@1|root,COG0715@2|Bacteria,46U3D@74201|Verrucomicrobia,2IU5R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
YYD3_k127_3941633_4	1254432.SCE1572_24300	7.817e-108	355.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,42Q2R@68525|delta/epsilon subdivisions,2X5I7@28221|Deltaproteobacteria,2Z1Z9@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
YYD3_k127_3941633_10	1254432.SCE1572_24295	3.586e-52	189.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02049,ko:K15578,ko:K15579	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	ABC_tran
YYD3_k127_3959542_1	1267533.KB906735_gene5073	1.152e-53	206.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD3_k127_3959542_0	1357272.AVEO02000153_gene1606	7.19e-72	247.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria,1Z755@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	Rubrerythrin	IV02_12050	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
YYD3_k127_3962440_1	1247726.MIM_c02340	2.237e-104	361.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
YYD3_k127_3962440_0	767434.Fraau_1178	3.045e-146	473.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1X3UF@135614|Xanthomonadales	135614|Xanthomonadales	JKL	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
YYD3_k127_3963979_3	998674.ATTE01000001_gene487	0.0003277	47.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,45ZQK@72273|Thiotrichales	72273|Thiotrichales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
YYD3_k127_3963979_1	204669.Acid345_2365	7.222e-92	318.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria,2JHW8@204432|Acidobacteriia	204432|Acidobacteriia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
YYD3_k127_3963979_0	1267535.KB906767_gene5475	4.467e-125	407.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YYD3_k127_3963979_2	401053.AciPR4_1940	1.484e-28	124.0	COG1266@1|root,COG1266@2|Bacteria,3Y4ED@57723|Acidobacteria,2JJ3Q@204432|Acidobacteriia	204432|Acidobacteriia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD3_k127_3974073_2	1278073.MYSTI_04823	1.696e-36	140.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,42NUM@68525|delta/epsilon subdivisions,2WKR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 2-nitropropane dioxygenase NPD	-	-	-	-	-	-	-	-	-	-	-	-	NMO
YYD3_k127_3974073_7	1340493.JNIF01000003_gene4709	3.307e-08	55.0	2EQTB@1|root,33ID2@2|Bacteria	2|Bacteria	S	Lytic polysaccharide mono-oxygenase, cellulose-degrading	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10
YYD3_k127_3974073_5	1090318.ATTI01000001_gene970	6.21e-17	93.0	COG3258@1|root,COG3258@2|Bacteria,1R0F2@1224|Proteobacteria,2TYQH@28211|Alphaproteobacteria,2K6ZI@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_3974073_0	1202532.FF52_15697	2.711e-147	477.0	COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,1I5BI@117743|Flavobacteriia,2NVIG@237|Flavobacterium	976|Bacteroidetes	S	COG NOG10142 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_3974073_1	1298867.AUES01000037_gene749	2.54e-95	318.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria,3K0RD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
YYD3_k127_3974073_4	329726.AM1_G0173	4.258e-17	92.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
YYD3_k127_3974073_6	1144275.COCOR_01698	3.016e-14	79.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,Collagen,DUF4347,FG-GAP,He_PIG,HemolysinCabind,TIG,VCBS
YYD3_k127_3974073_3	765869.BDW_08765	1.604e-22	103.0	COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,42SR2@68525|delta/epsilon subdivisions,2MTYT@213481|Bdellovibrionales,2X5JF@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
YYD3_k127_3975882_0	667014.Thein_0591	9.936e-203	646.0	COG0173@1|root,COG0173@2|Bacteria,2GGSQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
YYD3_k127_3975882_1	999423.HMPREF9161_00546	1.806e-13	74.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes	909932|Negativicutes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
YYD3_k127_3998136_6	697282.Mettu_2234	1.023e-21	105.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_3998136_1	1211115.ALIQ01000018_gene2164	1.251e-97	334.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	glucose sorbosone	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
YYD3_k127_3998136_3	204669.Acid345_0713	4.512e-60	212.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria,2JIGK@204432|Acidobacteriia	204432|Acidobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
YYD3_k127_3998136_7	1267535.KB906767_gene1485	8.298e-19	87.0	COG0291@1|root,COG0291@2|Bacteria,3Y5GU@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
YYD3_k127_3998136_4	240015.ACP_2248	6.438e-40	154.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
YYD3_k127_3998136_5	574087.Acear_0397	1.775e-32	132.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WAA5@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YYD3_k127_3998136_2	351627.Csac_1848	6.634e-73	249.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
YYD3_k127_3998136_0	1125863.JAFN01000001_gene1869	1.28e-112	378.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
YYD3_k127_4005787_0	118173.KB235914_gene3105	1.803e-39	162.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_4005787_1	1500304.JQKY01000008_gene3104	4.677e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,1PG3T@1224|Proteobacteria,2V3M0@28211|Alphaproteobacteria,4BFHI@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_4005787_2	1227739.Hsw_2266	2.45e-11	72.0	COG2510@1|root,COG2510@2|Bacteria,4P4N3@976|Bacteroidetes	976|Bacteroidetes	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
YYD3_k127_4005787_3	555793.WSK_2874	2.365e-08	59.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4025629_6	935840.JAEQ01000003_gene279	2.106e-55	196.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	2.1.1.341	ko:K15066	ko00627,ko01120,map00627,map01120	-	R09271,R10136	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_4025629_4	330214.NIDE4162	3.092e-83	282.0	COG0177@1|root,COG0177@2|Bacteria,3J0K6@40117|Nitrospirae	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2,4.2.99.18	ko:K01142,ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
YYD3_k127_4025629_1	1267535.KB906767_gene2589	2.791e-181	586.0	COG0405@1|root,COG0405@2|Bacteria,3Y2I7@57723|Acidobacteria,2JKP3@204432|Acidobacteriia	204432|Acidobacteriia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
YYD3_k127_4025629_7	1112204.GPOL_c07810	1.118e-43	166.0	COG1321@1|root,COG1321@2|Bacteria,2I42V@201174|Actinobacteria,4GGVW@85026|Gordoniaceae	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4025629_3	1502852.FG94_03397	3.016e-102	345.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2VRA9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
YYD3_k127_4025629_5	234267.Acid_5827	2.066e-67	246.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4025629_2	1502852.FG94_01090	2.83e-114	397.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VIZX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
YYD3_k127_4025629_0	330214.NIDE1067	7.185e-224	714.0	2DBJW@1|root,2Z9P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4031640_5	204669.Acid345_1582	1.083e-05	51.0	2EEIP@1|root,338CM@2|Bacteria,3Y5Q1@57723|Acidobacteria,2JK0Z@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4031640_0	246194.CHY_1607	1.43e-160	522.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,24C0I@186801|Clostridia,42HWH@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD3_k127_4031640_1	1128427.KB904821_gene1906	4.117e-119	397.0	COG0014@1|root,COG0014@2|Bacteria,1G1NS@1117|Cyanobacteria,1H6XU@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD3_k127_4031640_3	429009.Adeg_0186	4.396e-60	218.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,42FBI@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
YYD3_k127_4031640_2	927677.ALVU02000001_gene1295	3.134e-69	244.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2912 conserved	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
YYD3_k127_4031640_4	330214.NIDE1522	2.962e-20	96.0	COG0637@1|root,COG0637@2|Bacteria,3J15X@40117|Nitrospirae	40117|Nitrospirae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
YYD3_k127_4042989_1	869210.Marky_0765	1.888e-12	73.0	COG4886@1|root,COG4886@2|Bacteria,1WNAX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Leucine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4042989_0	522306.CAP2UW1_2609	5.331e-91	322.0	COG1192@1|root,COG1357@1|root,COG1787@1|root,COG2319@1|root,COG5635@1|root,COG1192@2|Bacteria,COG1357@2|Bacteria,COG1787@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
YYD3_k127_4070748_4	278963.ATWD01000002_gene825	8.797e-30	130.0	COG1629@1|root,COG4771@2|Bacteria,3Y3EI@57723|Acidobacteria,2JIWK@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4070748_0	234267.Acid_7841	3.31e-164	566.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4070748_2	1453501.JELR01000002_gene185	1.576e-64	232.0	COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,4673D@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	EamA-like transporter family	yhbE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
YYD3_k127_4070748_1	1121920.AUAU01000004_gene584	7.048e-80	272.0	COG0744@1|root,COG0744@2|Bacteria,3Y48X@57723|Acidobacteria	57723|Acidobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
YYD3_k127_4070748_3	1267535.KB906767_gene904	9.101e-60	216.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_4081723_2	472759.Nhal_3042	2.169e-172	548.0	COG0843@1|root,COG1845@1|root,COG0843@2|Bacteria,COG1845@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X04R@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K15408	ko00190,map00190	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX1
YYD3_k127_4081723_11	1109445.AGSX01000083_gene3095	2.277e-23	104.0	2E5ZP@1|root,330P3@2|Bacteria,1MZC5@1224|Proteobacteria,1TA1Z@1236|Gammaproteobacteria,1Z44I@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4081723_7	344747.PM8797T_02559	4.222e-51	190.0	COG3336@1|root,COG3336@2|Bacteria,2J2XG@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
YYD3_k127_4081723_9	1007105.PT7_0930	8.476e-24	105.0	COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,1MW1W@1224|Proteobacteria,2VQSF@28216|Betaproteobacteria,3T721@506|Alcaligenaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_4081723_10	1267535.KB906767_gene4139	1.918e-23	110.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GJ@57723|Acidobacteria,2JJ01@204432|Acidobacteriia	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
YYD3_k127_4081723_8	543728.Vapar_0698	1.883e-31	134.0	COG2010@1|root,COG2010@2|Bacteria,1RHET@1224|Proteobacteria,2W3EV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
YYD3_k127_4081723_4	935840.JAEQ01000003_gene71	5.522e-86	293.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,43JJK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
YYD3_k127_4081723_0	536019.Mesop_4366	5.834e-275	858.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_4081723_3	1454004.AW11_02393	3.354e-89	308.0	COG4313@1|root,COG4313@2|Bacteria,1PRCN@1224|Proteobacteria,2VQHT@28216|Betaproteobacteria,1KQK1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YYD3_k127_4081723_1	159450.NH14_15325	1.17e-218	687.0	COG4320@1|root,COG4320@2|Bacteria,1N6EW@1224|Proteobacteria,2VN9A@28216|Betaproteobacteria,1K2DQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
YYD3_k127_4081723_12	882.DVU_0243	7.524e-22	106.0	28PW7@1|root,32EDN@2|Bacteria,1N0AP@1224|Proteobacteria,42UF5@68525|delta/epsilon subdivisions,2WQ2P@28221|Deltaproteobacteria,2MCNN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
YYD3_k127_4081723_13	1267535.KB906767_gene3098	1.984e-21	105.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria,2JJBS@204432|Acidobacteriia	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_4081723_6	714943.Mucpa_3708	3.383e-73	250.0	COG0262@1|root,COG0262@2|Bacteria,4NHIH@976|Bacteroidetes,1J05Q@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
YYD3_k127_4081723_5	326297.Sama_1484	2.489e-85	297.0	COG3137@1|root,COG3137@2|Bacteria,1RCKQ@1224|Proteobacteria,1S0GK@1236|Gammaproteobacteria,2QA2B@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
YYD3_k127_4088099_3	1210884.HG799466_gene12434	5.159e-13	70.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,AraC_binding,DJ-1_PfpI,HTH_18,HTH_AraC
YYD3_k127_4088099_0	215803.DB30_7635	3.899e-101	339.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,433T9@68525|delta/epsilon subdivisions,2X3CY@28221|Deltaproteobacteria,2YTTY@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD3_k127_4088099_2	1191523.MROS_0856	3.761e-38	150.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
YYD3_k127_4088099_1	450851.PHZ_c1570	8.055e-46	173.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2TRZF@28211|Alphaproteobacteria,2KFJW@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M61 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
YYD3_k127_4111712_0	366602.Caul_0720	1.023e-124	422.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWFB@28211|Alphaproteobacteria,2KFH9@204458|Caulobacterales	204458|Caulobacterales	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg
YYD3_k127_4111712_3	622637.KE124774_gene658	3.671e-07	62.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,2TUT1@28211|Alphaproteobacteria,36ZM4@31993|Methylocystaceae	28211|Alphaproteobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
YYD3_k127_4111712_2	234267.Acid_0308	3.564e-41	154.0	COG3118@1|root,COG3118@2|Bacteria,3Y53D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
YYD3_k127_4111712_1	203122.Sde_2661	2.444e-54	195.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,464CH@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
YYD3_k127_4114336_7	265072.Mfla_0721	2.987e-47	178.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIGR@28216|Betaproteobacteria,2KKNQ@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S
YYD3_k127_4114336_5	1283300.ATXB01000001_gene1026	2.437e-58	208.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1XF7D@135618|Methylococcales	135618|Methylococcales	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx
YYD3_k127_4114336_2	1210884.HG799466_gene12383	9.187e-92	312.0	COG1526@1|root,COG1526@2|Bacteria,2IZ61@203682|Planctomycetes	203682|Planctomycetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
YYD3_k127_4114336_4	1122621.ATZA01000017_gene3936	1.467e-74	272.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
YYD3_k127_4114336_12	1340493.JNIF01000003_gene2122	5.26e-17	89.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4114336_9	1236959.BAMT01000015_gene2850	1.167e-28	128.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4114336_1	234267.Acid_5561	8.346e-143	462.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
YYD3_k127_4114336_10	1267535.KB906767_gene928	1.909e-26	118.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
YYD3_k127_4114336_0	861299.J421_1516	3.482e-167	542.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD3_k127_4114336_8	382464.ABSI01000010_gene3793	1.204e-34	141.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
YYD3_k127_4114336_11	1499967.BAYZ01000081_gene1047	8.4e-26	114.0	COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4114336_3	686340.Metal_0152	3.705e-78	274.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1XFND@135618|Methylococcales	135618|Methylococcales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
YYD3_k127_4114336_6	243231.GSU0525	2.701e-51	187.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,43UNI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
YYD3_k127_4124886_11	1386969.AWTB01000002_gene1913	0.0003	49.0	COG0596@1|root,COG0596@2|Bacteria,2HKK5@201174|Actinobacteria,4GDK9@85026|Gordoniaceae	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_4124886_8	234267.Acid_3553	1.148e-16	88.0	2CK2Y@1|root,32SBF@2|Bacteria,3Y5PZ@57723|Acidobacteria	57723|Acidobacteria	S	Photosynthetic reaction centre cytochrome C subunit	-	-	-	-	-	-	-	-	-	-	-	-	CytoC_RC
YYD3_k127_4124886_6	240015.ACP_1413	3.042e-19	96.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
YYD3_k127_4124886_4	234267.Acid_4153	1.443e-53	207.0	COG1538@1|root,COG1538@2|Bacteria,3Y5F3@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD3_k127_4124886_2	671143.DAMO_1932	1.592e-75	268.0	COG0845@1|root,COG0845@2|Bacteria,2NPS3@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
YYD3_k127_4124886_0	671143.DAMO_1933	0.0	1316.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YYD3_k127_4124886_7	1267533.KB906738_gene2301	9.795e-18	89.0	COG2149@1|root,COG2149@2|Bacteria	2|Bacteria	S	membrane	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
YYD3_k127_4124886_3	383372.Rcas_3624	2.177e-68	239.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YYD3_k127_4124886_5	1191523.MROS_0796	7.785e-51	183.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
YYD3_k127_4124886_1	596153.Alide_2745	2.781e-143	471.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria,4AF43@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM multicopper oxidase type	-	-	1.3.3.5	ko:K08100,ko:K14588	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
YYD3_k127_4142047_0	497964.CfE428DRAFT_5468	1.367e-111	372.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
YYD3_k127_4142047_1	240016.ABIZ01000001_gene3846	4.675e-15	75.0	COG0174@1|root,COG0174@2|Bacteria,46S5C@74201|Verrucomicrobia,2ITKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamine synthetase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Gln-synt_C,Gln-synt_N
YYD3_k127_4168808_2	204669.Acid345_4634	3.324e-80	275.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria,2JHJZ@204432|Acidobacteriia	204432|Acidobacteriia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
YYD3_k127_4168808_3	228410.NE0221	5.264e-70	243.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,372MM@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
YYD3_k127_4168808_1	880073.Calab_2509	2.662e-93	311.0	COG0603@1|root,COG0603@2|Bacteria,2NPD6@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
YYD3_k127_4168808_4	1267535.KB906767_gene5189	1.151e-24	118.0	COG0457@1|root,COG0457@2|Bacteria,3Y3BD@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11,TPR_16,TPR_2,TPR_8
YYD3_k127_4168808_5	55529.EKX43840	1.143e-08	63.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	2.4.1.255,5.3.4.1	ko:K09580,ko:K09667	ko00514,ko04141,ko04931,map00514,map04141,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036,ko03110,ko04131,ko04147	-	GT41	-	Glyco_transf_41,TPR_11,TPR_16,TPR_8
YYD3_k127_4168808_0	234267.Acid_2857	0.0	1103.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria	57723|Acidobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
YYD3_k127_4173986_2	224324.aq_1039	1.031e-99	330.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G3I5@200783|Aquificae	200783|Aquificae	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
YYD3_k127_4173986_1	234267.Acid_0836	2.869e-110	364.0	COG0437@1|root,COG0437@2|Bacteria,3Y65I@57723|Acidobacteria	57723|Acidobacteria	C	Formate dehydrogenase N, transmembrane	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Form-deh_trans
YYD3_k127_4173986_4	932678.THERU_02620	1.585e-48	183.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	fdoI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K00127,ko:K08350	ko00630,ko00680,ko01100,ko01120,ko01200,ko02020,map00630,map00680,map01100,map01120,map01200,map02020	-	R00519	RC02796	ko00000,ko00001	5.A.3.2	-	iEC042_1314.EC042_1608,iECED1_1282.ECED1_1627,iECNA114_1301.ECNA114_3649,iECSF_1327.ECSF_1390,iECUMN_1333.ECUMN_1730,ic_1306.c1907	Ni_hydr_CYTB
YYD3_k127_4173986_5	234267.Acid_0834	2.735e-31	138.0	COG3058@1|root,COG3058@2|Bacteria,3Y87B@57723|Acidobacteria	57723|Acidobacteria	O	protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
YYD3_k127_4173986_3	1144275.COCOR_03213	1.041e-83	293.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
YYD3_k127_4173986_0	861299.J421_5941	9.126e-134	443.0	COG3276@1|root,COG3276@2|Bacteria	2|Bacteria	J	selenocysteine insertion sequence binding	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
YYD3_k127_4182882_2	390874.Tpet_1383	2.659e-78	274.0	COG0075@1|root,COG0075@2|Bacteria,2GCGI@200918|Thermotogae	200918|Thermotogae	E	PFAM aminotransferase class V	-	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	-	-	-	-	-	-	-	-	-	Aminotran_5
YYD3_k127_4182882_0	330214.NIDE1289	8.584e-265	832.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
YYD3_k127_4182882_4	1415630.U771_00415	2.728e-15	78.0	2EGJ5@1|root,33ABC@2|Bacteria,1NI51@1224|Proteobacteria,1SH35@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1161)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1161
YYD3_k127_4182882_5	693661.Arcve_0308	6.916e-05	51.0	COG0454@1|root,arCOG00826@2157|Archaea,2XXYN@28890|Euryarchaeota,246C2@183980|Archaeoglobi	183980|Archaeoglobi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_4182882_3	1192034.CAP_3929	2.257e-72	258.0	COG1262@1|root,COG1262@2|Bacteria,1QA4V@1224|Proteobacteria,43DXT@68525|delta/epsilon subdivisions,2WZ5G@28221|Deltaproteobacteria,2Z1DE@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4182882_1	330214.NIDE4254	1.144e-119	392.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_4194874_0	933262.AXAM01000033_gene1633	5.475e-06	57.0	2EKB4@1|root,33E1H@2|Bacteria,1NJTI@1224|Proteobacteria,432QN@68525|delta/epsilon subdivisions,2WX6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YYD3_k127_4228679_0	1340493.JNIF01000003_gene3748	2.068e-318	1005.0	COG3485@1|root,COG3485@2|Bacteria,3Y3VM@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4228679_1	234267.Acid_2841	4.162e-36	141.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria	2|Bacteria	P	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,PBP_like
YYD3_k127_4235506_0	269482.Bcep1808_5021	1.553e-116	385.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
YYD3_k127_4243020_0	234267.Acid_2395	0.0	1422.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria	57723|Acidobacteria	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YYD3_k127_4257270_0	136993.KB900627_gene392	2.547e-54	198.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4257270_1	1335760.ASTG01000003_gene1751	1.71e-36	149.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4257270_3	136993.KB900627_gene391	5.54e-30	125.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4257270_2	335541.Swol_1667	2.413e-32	138.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia,42KKD@68298|Syntrophomonadaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
YYD3_k127_4257270_4	472175.EL18_00668	1.699e-09	68.0	COG1670@1|root,COG3103@1|root,COG1670@2|Bacteria,COG4991@2|Bacteria,1NMZ9@1224|Proteobacteria	1224|Proteobacteria	J	exported protein of Yersinia	-	-	-	-	-	-	-	-	-	-	-	-	Crystall,Crystall_3,Exotox-A_bind,Inhibitor_I36
YYD3_k127_4300268_3	472759.Nhal_1083	4.669e-15	87.0	COG3474@1|root,COG3474@2|Bacteria,1QWSY@1224|Proteobacteria,1T3TY@1236|Gammaproteobacteria,1X2PV@135613|Chromatiales	135613|Chromatiales	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
YYD3_k127_4300268_2	1267535.KB906767_gene4941	5.739e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,3Y5K8@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4300268_4	459495.SPLC1_S011080	1.742e-11	70.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,1FZWT@1117|Cyanobacteria,1H90D@1150|Oscillatoriales	1117|Cyanobacteria	CO	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
YYD3_k127_4300268_1	1122621.ATZA01000011_gene415	6.983e-32	134.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1ISGX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
YYD3_k127_4300268_0	330214.NIDE0820	2.852e-46	169.0	COG0780@1|root,COG0780@2|Bacteria,3J0R4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
YYD3_k127_4311955_0	1122603.ATVI01000005_gene3568	1.783e-153	496.0	COG0154@1|root,COG0154@2|Bacteria	2|Bacteria	J	amidase activity	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_4311955_2	926566.Terro_0412	3.496e-31	129.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4311955_1	234267.Acid_4463	3.804e-91	309.0	COG3605@1|root,COG3707@1|root,COG3605@2|Bacteria,COG3707@2|Bacteria	2|Bacteria	T	response regulator	nasR	-	4.6.1.1	ko:K01768,ko:K02584,ko:K07183,ko:K22010	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00839	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03000	-	-	-	ANTAR,GAF_2,Response_reg
YYD3_k127_4331542_0	1047013.AQSP01000109_gene2437	2.281e-307	960.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_4331542_4	693986.MOC_4821	8.457e-12	69.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,1JZAV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD3_k127_4331542_1	204669.Acid345_4041	1.239e-64	224.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJC7@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
YYD3_k127_4331542_3	234267.Acid_0794	5.757e-28	125.0	COG0392@1|root,COG0392@2|Bacteria,3Y3SG@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
YYD3_k127_4331542_2	234267.Acid_0793	5.554e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4331542_5	1380390.JIAT01000009_gene612	0.0007658	47.0	COG5660@1|root,COG5660@2|Bacteria,2HRSR@201174|Actinobacteria,4CTVV@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD3_k127_4334237_9	204669.Acid345_1394	6.62e-37	143.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria,2JIIE@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_4334237_1	748247.AZKH_2916	4.002e-184	587.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VH71@28216|Betaproteobacteria,2KYBQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Aldehyde dehydrogenase family	-	-	1.2.1.28,1.2.1.67	ko:K00141,ko:K21802	ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R05699,R07667	RC00075	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD3_k127_4334237_12	546274.EIKCOROL_01892	1.088e-22	105.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,2KQYT@206351|Neisseriales	206351|Neisseriales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
YYD3_k127_4334237_0	448385.sce9321	4.617e-215	683.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria,2YYAR@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
YYD3_k127_4334237_7	1397699.JNIS01000001_gene2565	4.409e-53	196.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,4HA3H@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
YYD3_k127_4334237_2	215803.DB30_0846	5.231e-105	364.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
YYD3_k127_4334237_6	404589.Anae109_1214	6.166e-55	202.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2Z36A@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
YYD3_k127_4334237_3	247490.KSU1_C0172	1.127e-71	263.0	COG0815@1|root,COG0815@2|Bacteria,2IWUW@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
YYD3_k127_4334237_13	1504319.GM45_0875	2.478e-20	106.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,3UXBJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Serine aminopeptidase, S33	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
YYD3_k127_4334237_14	358681.BBR47_17730	5.573e-06	59.0	COG1075@1|root,COG3209@1|root,COG1075@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26RI4@186822|Paenibacillaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,Thioesterase
YYD3_k127_4334237_4	234267.Acid_5283	1.722e-67	245.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YYD3_k127_4334237_10	1267535.KB906767_gene4539	2.766e-30	132.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4334237_5	1123060.JONP01000007_gene5047	7.616e-64	226.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Phytase-like
YYD3_k127_4334237_8	204669.Acid345_2557	6.862e-42	160.0	2B7KW@1|root,320RZ@2|Bacteria,3Y7ZF@57723|Acidobacteria,2JN97@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4334237_11	204669.Acid345_1151	8.46e-28	117.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria,2JIBK@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
YYD3_k127_4335853_0	1379270.AUXF01000001_gene2017	9.702e-227	734.0	COG5549@1|root,COG5549@2|Bacteria,1ZTC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
YYD3_k127_4335853_13	1082931.KKY_100	7.393e-50	185.0	2CBAE@1|root,34691@2|Bacteria,1N1N6@1224|Proteobacteria,2UD3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4335853_14	1082931.KKY_101	8.401e-48	177.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2VCYT@28211|Alphaproteobacteria,3N96R@45401|Hyphomicrobiaceae	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4335853_18	1379698.RBG1_1C00001G0628	5.625e-11	75.0	2DDTE@1|root,2ZJ6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4335853_10	443598.AUFA01000012_gene4878	1.367e-99	331.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,3JVAI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
YYD3_k127_4335853_11	716928.AJQT01000028_gene2339	1.732e-96	319.0	COG5588@1|root,COG5588@2|Bacteria,1PZHC@1224|Proteobacteria,2TVVV@28211|Alphaproteobacteria,4BBPN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
YYD3_k127_4335853_12	870187.Thini_2725	3.651e-80	280.0	COG0834@1|root,COG0834@2|Bacteria,1P18B@1224|Proteobacteria,1T0T9@1236|Gammaproteobacteria,463D0@72273|Thiotrichales	72273|Thiotrichales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SBP_bac_3
YYD3_k127_4335853_6	1185876.BN8_04244	2.018e-140	464.0	COG1231@1|root,COG1231@2|Bacteria,4NJU7@976|Bacteroidetes,47NP2@768503|Cytophagia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
YYD3_k127_4335853_3	1278073.MYSTI_06285	2.854e-164	534.0	COG0464@1|root,COG0464@2|Bacteria,1RCHW@1224|Proteobacteria,42Z41@68525|delta/epsilon subdivisions,2WU9F@28221|Deltaproteobacteria,2YUT7@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
YYD3_k127_4335853_17	1242864.D187_006513	4.039e-14	83.0	2EDTI@1|root,337NU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4335853_16	246197.MXAN_5703	2.003e-20	100.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria	1224|Proteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
YYD3_k127_4335853_5	395493.BegalDRAFT_1035	6.768e-145	465.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,4600F@72273|Thiotrichales	72273|Thiotrichales	H	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YYD3_k127_4335853_4	395493.BegalDRAFT_1036	2.783e-146	475.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,45ZUS@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_4335853_2	211114.JOEF01000015_gene3525	2.216e-196	630.0	COG0326@1|root,COG0326@2|Bacteria,2GNPQ@201174|Actinobacteria,4DZ66@85010|Pseudonocardiales	201174|Actinobacteria	O	Molecular chaperone. Has ATPase activity	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0010035,GO:0016020,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
YYD3_k127_4335853_1	518766.Rmar_1231	8.788e-218	688.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1FIW6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
YYD3_k127_4335853_9	1337936.IJ00_09705	9.62e-100	342.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1HKZ8@1161|Nostocales	1117|Cyanobacteria	EGP	major facilitator superfamily MFS_1	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
YYD3_k127_4335853_7	1379270.AUXF01000001_gene1893	1.669e-124	415.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_4353173_7	215803.DB30_8034	2.71e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4353173_0	1267535.KB906767_gene4658	3.112e-231	730.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,3Y3TK@57723|Acidobacteria,2JIM5@204432|Acidobacteriia	204432|Acidobacteriia	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
YYD3_k127_4353173_1	1267535.KB906767_gene4657	4.001e-154	500.0	COG3852@1|root,COG3852@2|Bacteria,3Y3JR@57723|Acidobacteria,2JIY1@204432|Acidobacteriia	204432|Acidobacteriia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
YYD3_k127_4353173_4	469617.FUAG_01637	3.432e-11	75.0	COG3779@1|root,COG3779@2|Bacteria,37AKK@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF4026)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314,DUF4026
YYD3_k127_4353173_2	1120971.AUCA01000022_gene543	9.835e-126	409.0	COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli	91061|Bacilli	F	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
YYD3_k127_4353173_5	272123.Anacy_2538	9.183e-10	65.0	COG1357@1|root,COG1357@2|Bacteria,1G0KS@1117|Cyanobacteria,1HQNV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
YYD3_k127_4353173_3	1453501.JELR01000002_gene977	3.392e-30	122.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,467AS@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291	Thioredoxin
YYD3_k127_4353173_6	1007103.AFHW01000096_gene3298	1.211e-09	60.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,26S26@186822|Paenibacillaceae	91061|Bacilli	L	DNA repair exonuclease	yhaO	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
YYD3_k127_4365625_0	234267.Acid_6847	2.866e-101	354.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4365625_1	1267535.KB906767_gene2983	2.509e-50	181.0	COG1695@1|root,COG1695@2|Bacteria,3Y7WK@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_4365625_2	1267535.KB906767_gene2984	3.594e-24	108.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_4397897_2	1267535.KB906767_gene4539	5.738e-32	134.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4397897_0	1122226.AUHX01000001_gene558	2.884e-75	283.0	COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
YYD3_k127_4397897_1	1382359.JIAL01000001_gene539	8.176e-73	266.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YYD3_k127_4398387_3	408672.NBCG_00826	5.629e-12	73.0	2EBIV@1|root,335JA@2|Bacteria,2IHZS@201174|Actinobacteria,4DRF2@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
YYD3_k127_4398387_0	309801.trd_A0425	3.301e-120	406.0	COG2268@1|root,COG2268@2|Bacteria,2GBEI@200795|Chloroflexi,27Z5S@189775|Thermomicrobia	189775|Thermomicrobia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
YYD3_k127_4398387_4	1267533.KB906735_gene4530	1.476e-09	61.0	COG1793@1|root,COG1793@2|Bacteria,3Y2VV@57723|Acidobacteria,2JIJ7@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase D, 3'-phosphoesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
YYD3_k127_4398387_1	234267.Acid_4748	7.889e-94	326.0	COG1858@1|root,COG1858@2|Bacteria,3Y7FY@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
YYD3_k127_4398387_2	211165.AJLN01000079_gene367	2.382e-52	186.0	COG3119@1|root,COG3119@2|Bacteria,1G3QV@1117|Cyanobacteria,1JJZ1@1189|Stigonemataceae	1117|Cyanobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YYD3_k127_4419943_0	234267.Acid_1734	2.866e-306	965.0	COG0612@1|root,COG0612@2|Bacteria,3Y2UB@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_4419943_1	1121035.AUCH01000005_gene125	1.496e-57	211.0	COG2199@1|root,COG3706@2|Bacteria,1MYK0@1224|Proteobacteria	1224|Proteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
YYD3_k127_4431731_2	555079.Toce_0450	2.41e-99	339.0	COG0477@1|root,COG2814@2|Bacteria,1UHNA@1239|Firmicutes,25F3B@186801|Clostridia,42J72@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
YYD3_k127_4431731_3	272123.Anacy_5623	1.023e-95	325.0	COG1893@1|root,COG1893@2|Bacteria,1G47S@1117|Cyanobacteria,1HMZR@1161|Nostocales	1117|Cyanobacteria	H	2-dehydropantoate 2-reductase	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
YYD3_k127_4431731_0	765420.OSCT_0800	9.028e-167	538.0	COG0318@1|root,COG0318@2|Bacteria,2G83V@200795|Chloroflexi,376U1@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
YYD3_k127_4431731_5	316057.RPD_1181	9.616e-40	159.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria,3JWK0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_4431731_10	326423.RBAM_018960	2.717e-05	56.0	COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4HCGU@91061|Bacilli,1ZFSM@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	yocH	-	-	-	-	-	-	-	-	-	-	-	3D,LysM
YYD3_k127_4431731_4	631362.Thi970DRAFT_01575	1.477e-66	241.0	COG0741@1|root,COG0741@2|Bacteria,1MWKE@1224|Proteobacteria,1RZWQ@1236|Gammaproteobacteria,1WW2K@135613|Chromatiales	135613|Chromatiales	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
YYD3_k127_4431731_1	869210.Marky_0518	1.773e-102	349.0	COG0446@1|root,COG0446@2|Bacteria,1WI5H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
YYD3_k127_4431731_7	497965.Cyan7822_2657	1.338e-16	89.0	COG0500@1|root,COG2226@2|Bacteria,1GIXW@1117|Cyanobacteria,3KJAY@43988|Cyanothece	1117|Cyanobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_4431731_9	886293.Sinac_3298	3.657e-06	55.0	2ESQD@1|root,33K8U@2|Bacteria,2J17D@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4431731_11	670487.Ocepr_0302	6.113e-05	49.0	2ENPW@1|root,33GB7@2|Bacteria,1WKTU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4431731_6	661478.OP10G_4733	5.287e-38	151.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	ampD	-	3.5.1.28	ko:K01447,ko:K03806,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1,SH3_3
YYD3_k127_4431731_8	1047013.AQSP01000141_gene118	6.28e-11	68.0	COG0642@1|root,COG3292@1|root,COG3920@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop
YYD3_k127_4435491_2	204536.SULAZ_1484	2.647e-44	166.0	COG2107@1|root,COG2107@2|Bacteria,2G4EE@200783|Aquificae	200783|Aquificae	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YYD3_k127_4435491_0	435591.BDI_3207	3.783e-74	263.0	COG0535@1|root,COG0535@2|Bacteria,4PA9R@976|Bacteroidetes,2FWDR@200643|Bacteroidia	976|Bacteroidetes	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
YYD3_k127_4435491_1	234267.Acid_1399	3.14e-45	179.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
YYD3_k127_4443253_4	266117.Rxyl_3183	2.083e-43	162.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
YYD3_k127_4443253_0	671143.DAMO_0704	5.08e-132	433.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_4443253_3	1267534.KB906754_gene3106	2.264e-66	248.0	COG1228@1|root,COG1228@2|Bacteria,3Y539@57723|Acidobacteria,2JKT2@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_4443253_1	1293054.HSACCH_01643	8.028e-102	342.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3WB2E@53433|Halanaerobiales	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
YYD3_k127_4443253_2	204669.Acid345_2621	4.022e-80	277.0	COG1619@1|root,COG1619@2|Bacteria,3Y3SS@57723|Acidobacteria,2JHRY@204432|Acidobacteriia	204432|Acidobacteriia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
YYD3_k127_4449621_4	204669.Acid345_4634	3.368e-88	302.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria,2JHJZ@204432|Acidobacteriia	204432|Acidobacteriia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
YYD3_k127_4449621_5	401526.TcarDRAFT_0624	1.297e-34	140.0	COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,4H481@909932|Negativicutes	909932|Negativicutes	S	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
YYD3_k127_4449621_6	1095769.CAHF01000006_gene1916	4.831e-26	112.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
YYD3_k127_4449621_7	547144.HydHO_0121	3.115e-24	104.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD3_k127_4449621_1	886293.Sinac_4702	7.721e-213	673.0	COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
YYD3_k127_4449621_2	404589.Anae109_2538	3.987e-153	490.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,42PDK@68525|delta/epsilon subdivisions,2WJKJ@28221|Deltaproteobacteria,2YTX7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
YYD3_k127_4449621_0	290397.Adeh_1230	0.0	1038.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria,2YUIB@29|Myxococcales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
YYD3_k127_4449621_3	411473.RUMCAL_02732	1.425e-125	417.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
YYD3_k127_4449621_8	234267.Acid_0018	8.987e-10	62.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
YYD3_k127_4465888_1	530564.Psta_1321	4.968e-21	106.0	COG1277@1|root,COG1277@2|Bacteria,2IZFI@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4465888_0	314230.DSM3645_25869	3.553e-96	323.0	COG1131@1|root,COG1131@2|Bacteria,2IWSX@203682|Planctomycetes	203682|Planctomycetes	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_4480644_4	639030.JHVA01000001_gene3524	5.187e-27	121.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria,2JHYC@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4480644_3	330214.NIDE3921	5.199e-28	123.0	29TFP@1|root,30ENV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
YYD3_k127_4480644_6	1380358.JADJ01000020_gene3483	6.294e-18	94.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1XJH9@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,OMP_b-brl,OmpA
YYD3_k127_4480644_8	1035197.HMPREF9999_02000	0.0002792	51.0	COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,1WDFU@1283313|Alloprevotella	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
YYD3_k127_4480644_2	234267.Acid_6760	1.737e-28	121.0	COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
YYD3_k127_4480644_5	1382359.JIAL01000001_gene525	2.438e-22	97.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JJZ9@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
YYD3_k127_4480644_0	234267.Acid_6758	4.895e-124	406.0	COG0416@1|root,COG0416@2|Bacteria,3Y3MM@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
YYD3_k127_4480644_1	204669.Acid345_4573	7.583e-109	360.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria,2JI6J@204432|Acidobacteriia	204432|Acidobacteriia	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
YYD3_k127_4487678_0	204669.Acid345_0212	2.657e-146	468.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
YYD3_k127_4487678_6	1049564.TevJSym_cd00020	3.902e-07	61.0	COG1409@1|root,COG2010@1|root,COG2863@1|root,COG2982@1|root,COG3469@1|root,COG4733@1|root,COG1409@2|Bacteria,COG2010@2|Bacteria,COG2863@2|Bacteria,COG2982@2|Bacteria,COG3469@2|Bacteria,COG4733@2|Bacteria,1RCAB@1224|Proteobacteria,1S529@1236|Gammaproteobacteria,1J9YI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	PA14,PSCyt3
YYD3_k127_4487678_4	204669.Acid345_0518	5.92e-46	175.0	COG3794@1|root,COG3794@2|Bacteria,3Y4UD@57723|Acidobacteria,2JJH0@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4487678_3	204669.Acid345_0519	4.371e-93	325.0	COG3074@1|root,COG3074@2|Bacteria,3Y983@57723|Acidobacteria,2JP4T@204432|Acidobacteriia	204432|Acidobacteriia	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4487678_5	420324.KI911961_gene1900	2.371e-16	89.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
YYD3_k127_4487678_2	682795.AciX8_3991	2.656e-105	351.0	COG0535@1|root,COG0535@2|Bacteria,3Y493@57723|Acidobacteria,2JM2X@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
YYD3_k127_4487678_1	1267534.KB906755_gene4049	2.555e-108	363.0	COG0402@1|root,COG0500@1|root,COG0402@2|Bacteria,COG2226@2|Bacteria,3Y3KZ@57723|Acidobacteria,2JIXX@204432|Acidobacteriia	204432|Acidobacteriia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Methyltransf_11,Methyltransf_25
YYD3_k127_4487678_7	1198114.AciX9_0571	0.0008316	44.0	COG0402@1|root,COG0500@1|root,COG0402@2|Bacteria,COG2226@2|Bacteria,3Y3KZ@57723|Acidobacteria,2JIXX@204432|Acidobacteriia	204432|Acidobacteriia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Methyltransf_11,Methyltransf_25
YYD3_k127_4493456_0	234267.Acid_7693	4.135e-260	814.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
YYD3_k127_4493456_1	240015.ACP_0329	2.967e-145	467.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
YYD3_k127_4493456_2	234267.Acid_2431	5.868e-95	325.0	2F63Z@1|root,33YN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4502218_3	697282.Mettu_2234	1.16e-57	206.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_4502218_7	136993.KB900627_gene392	4.395e-05	54.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4502218_2	35720.XP_003648538.1	1.535e-69	246.0	2EBD3@1|root,2SHGJ@2759|Eukaryota,39TQZ@33154|Opisthokonta,3NZP0@4751|Fungi,3QR77@4890|Ascomycota,218S5@147550|Sordariomycetes,3UABU@5139|Sordariales,3HAHA@35718|Chaetomiaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4502218_1	234267.Acid_1937	2.246e-234	736.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
YYD3_k127_4502218_0	234267.Acid_1936	5.525e-314	976.0	COG0021@1|root,COG0021@2|Bacteria,3Y62E@57723|Acidobacteria	57723|Acidobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
YYD3_k127_4502218_4	639030.JHVA01000001_gene3230	7.193e-55	194.0	COG0662@1|root,COG0662@2|Bacteria,3Y83R@57723|Acidobacteria	57723|Acidobacteria	G	Ectoine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_4518948_1	1056512.D515_04271	1.929e-70	243.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1XUS7@135623|Vibrionales	135623|Vibrionales	E	Urea ABC transporter ATP-binding protein	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
YYD3_k127_4518948_2	525919.Apre_0725	4.112e-41	153.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia,22HDM@1570339|Peptoniphilaceae	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
YYD3_k127_4518948_3	345219.Bcoa_1893	4.381e-40	153.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli,1ZH2P@1386|Bacillus	91061|Bacilli	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
YYD3_k127_4518948_0	635013.TherJR_0607	2.831e-143	458.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,260ZR@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
YYD3_k127_454747_2	204669.Acid345_0135	7.8e-67	239.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,3Y4PB@57723|Acidobacteria,2JJAU@204432|Acidobacteriia	204432|Acidobacteriia	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
YYD3_k127_454747_1	1330700.JQNC01000003_gene667	5.626e-78	272.0	COG0157@1|root,COG0157@2|Bacteria,1WIHZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
YYD3_k127_454747_0	269799.Gmet_0956	0.0	1030.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
YYD3_k127_454747_3	404589.Anae109_1476	3.406e-27	121.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_455935_1	234267.Acid_7679	1.396e-105	358.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_455935_0	234267.Acid_7841	2.115e-172	565.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4561342_3	234267.Acid_5856	4.001e-49	188.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4561342_1	234267.Acid_7677	4.277e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_4561342_0	1267535.KB906767_gene5360	6.899e-67	239.0	COG3622@1|root,COG3622@2|Bacteria,3Y6XP@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YYD3_k127_4561342_5	1380394.JADL01000011_gene3841	3.89e-07	53.0	COG0451@1|root,COG0451@2|Bacteria,1QP8J@1224|Proteobacteria,2U09V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
YYD3_k127_4561342_2	234267.Acid_7882	7.201e-56	204.0	COG5587@1|root,COG5587@2|Bacteria,3Y4D4@57723|Acidobacteria	57723|Acidobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
YYD3_k127_4561342_4	1123508.JH636449_gene7450	7.594e-30	119.0	COG0205@1|root,COG0205@2|Bacteria,2IYE1@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	-	-	-	-	-	-	-	-	-	-	PFK
YYD3_k127_4574187_3	886293.Sinac_1153	1.579e-52	195.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4574187_0	1340493.JNIF01000003_gene3965	1.235e-117	393.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_4574187_1	1340493.JNIF01000003_gene3965	1.409e-110	371.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
YYD3_k127_4574187_2	378806.STAUR_6602	1.671e-65	231.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,2YVDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Iron/manganese superoxide dismutases, C-terminal domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
YYD3_k127_4578613_0	864702.OsccyDRAFT_4267	7.889e-122	400.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria,1H7C1@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
YYD3_k127_4578613_1	649638.Trad_2051	5.105e-52	194.0	COG0668@1|root,COG0668@2|Bacteria,1WJII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
YYD3_k127_4580220_0	234267.Acid_7841	4.651e-140	495.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4580220_2	234267.Acid_7677	5.003e-56	201.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_4580220_1	234267.Acid_7637	1.005e-126	439.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4611792_2	497964.CfE428DRAFT_2125	5.285e-11	63.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
YYD3_k127_4611792_1	497964.CfE428DRAFT_2117	1.339e-49	192.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD3_k127_4611792_0	404589.Anae109_0139	1.052e-124	414.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YYD3_k127_4620512_1	324602.Caur_2056	1.49e-21	100.0	COG2203@1|root,COG2204@1|root,COG3852@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,2GBJN@200795|Chloroflexi,3780Z@32061|Chloroflexia	32061|Chloroflexia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
YYD3_k127_4620512_0	379066.GAU_3214	2.903e-77	268.0	28J2H@1|root,2Z8YZ@2|Bacteria,1ZUTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_462407_5	251221.35211172	6.677e-50	183.0	COG0586@1|root,COG0586@2|Bacteria,1G4C6@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
YYD3_k127_462407_4	234267.Acid_6218	6.148e-52	197.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_462407_3	251221.35212216	7.236e-56	200.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_462407_0	269799.Gmet_0304	1.145e-286	905.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,42NS6@68525|delta/epsilon subdivisions,2WKYJ@28221|Deltaproteobacteria,43SD8@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
YYD3_k127_462407_1	189753.AXAS01000036_gene7799	4.634e-130	439.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
YYD3_k127_462407_7	858215.Thexy_0756	5.313e-23	117.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	TNT
YYD3_k127_462407_2	1340493.JNIF01000003_gene2077	1.244e-98	366.0	COG3209@1|root,COG3209@2|Bacteria,3Y5Q3@57723|Acidobacteria	2|Bacteria	M	COG3209 Rhs family protein	tccC1	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	-
YYD3_k127_462407_6	1121918.ARWE01000001_gene2251	4.744e-41	153.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,43SAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD3_k127_4656541_3	1173028.ANKO01000214_gene6274	6.173e-64	226.0	COG1776@1|root,COG1776@2|Bacteria,1G9M7@1117|Cyanobacteria,1HHRB@1150|Oscillatoriales	1117|Cyanobacteria	NT	CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
YYD3_k127_4656541_5	401526.TcarDRAFT_0869	2.777e-34	136.0	COG0745@1|root,COG0745@2|Bacteria	401526.TcarDRAFT_0869|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4656541_1	1173028.ANKO01000214_gene6271	2.389e-147	474.0	COG2201@1|root,COG2201@2|Bacteria,1G2N5@1117|Cyanobacteria,1H741@1150|Oscillatoriales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
YYD3_k127_4656541_2	1173028.ANKO01000214_gene6276	5.37e-89	302.0	COG1352@1|root,COG1352@2|Bacteria,1G4QS@1117|Cyanobacteria,1H8YH@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575,ko:K13486	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
YYD3_k127_4656541_0	1173028.ANKO01000214_gene6277	3.353e-196	634.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
YYD3_k127_4656541_4	1173029.JH980292_gene2726	2.752e-63	229.0	COG0840@1|root,COG0840@2|Bacteria,1G4MY@1117|Cyanobacteria,1HA77@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
YYD3_k127_4657009_2	1267535.KB906767_gene5077	2.259e-81	274.0	COG3128@1|root,COG3128@2|Bacteria,3Y2N4@57723|Acidobacteria,2JHJ8@204432|Acidobacteriia	204432|Acidobacteriia	S	2OG-Fe(II) oxygenase	-	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
YYD3_k127_4657009_4	745310.G432_05645	2.392e-06	52.0	COG2906@1|root,COG2906@2|Bacteria,1PBPB@1224|Proteobacteria,2UM95@28211|Alphaproteobacteria,2K6XK@204457|Sphingomonadales	204457|Sphingomonadales	P	BFD-like [2Fe-2S] binding domain	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
YYD3_k127_4657009_3	1116472.MGMO_53c00060	1.11e-58	208.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,1S45S@1236|Gammaproteobacteria,1XF2W@135618|Methylococcales	135618|Methylococcales	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
YYD3_k127_4657009_1	926560.KE387023_gene3737	4.905e-161	514.0	COG3386@1|root,COG3386@2|Bacteria,1WN6C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
YYD3_k127_4657009_0	1267535.KB906767_gene4725	3.469e-228	710.0	COG2133@1|root,COG2133@2|Bacteria,3Y36R@57723|Acidobacteria,2JIPT@204432|Acidobacteriia	204432|Acidobacteriia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_4658737_9	1121933.AUHH01000010_gene2557	1.754e-33	135.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4DNUN@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
YYD3_k127_4658737_0	404589.Anae109_3731	1.917e-151	510.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
YYD3_k127_4658737_4	290400.Jann_3803	2.251e-79	274.0	COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,2TTCF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
YYD3_k127_4658737_10	509190.Cseg_2948	7.454e-15	87.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2KK0D@204458|Caulobacterales	204458|Caulobacterales	S	Retroviral aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
YYD3_k127_4658737_8	240015.ACP_2944	5.18e-41	156.0	COG0102@1|root,COG0102@2|Bacteria,3Y4U5@57723|Acidobacteria,2JJGG@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
YYD3_k127_4658737_7	1267535.KB906767_gene4506	7.11e-47	171.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria,2JJ7P@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
YYD3_k127_4658737_1	240015.ACP_2946	2.609e-116	380.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
YYD3_k127_4658737_3	243231.GSU1920	1.944e-83	283.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,43U1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
YYD3_k127_4658737_2	1232410.KI421418_gene2263	6.634e-102	337.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
YYD3_k127_4658737_6	240015.ACP_2312	6.466e-68	235.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria,2JJ0X@204432|Acidobacteriia	204432|Acidobacteriia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
YYD3_k127_4658737_5	1089552.KI911559_gene2203	1.589e-75	264.0	COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria,2JSIY@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0685 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
YYD3_k127_4659623_5	1133849.O3I_005690	2.234e-62	225.0	28HUE@1|root,2Z815@2|Bacteria,2GMGU@201174|Actinobacteria,4FYEI@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4659623_6	1047013.AQSP01000120_gene970	1.382e-56	211.0	COG2367@1|root,COG2367@2|Bacteria,2NQ4B@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
YYD3_k127_4659623_2	58123.JOFJ01000015_gene4408	9.486e-131	441.0	COG0220@1|root,COG0220@2|Bacteria,2IEHH@201174|Actinobacteria	201174|Actinobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4659623_9	234267.Acid_2629	1.555e-31	141.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4659623_3	627192.SLG_26300	2.958e-105	355.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4659623_8	278963.ATWD01000002_gene983	9.642e-34	138.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD3_k127_4659623_0	1267535.KB906767_gene824	2.352e-217	683.0	COG1070@1|root,COG1070@2|Bacteria,3Y2V6@57723|Acidobacteria,2JJ35@204432|Acidobacteriia	204432|Acidobacteriia	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
YYD3_k127_4659623_1	1340493.JNIF01000003_gene3534	1.608e-197	622.0	COG2115@1|root,COG2115@2|Bacteria,3Y841@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the xylose isomerase family	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
YYD3_k127_4659623_4	401526.TcarDRAFT_2305	1.631e-80	273.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4H376@909932|Negativicutes	909932|Negativicutes	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
YYD3_k127_4659623_7	234267.Acid_2122	2.363e-56	207.0	COG0524@1|root,COG0524@2|Bacteria,3Y6VV@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
YYD3_k127_4665359_1	639030.JHVA01000001_gene1897	6.081e-10	67.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4665359_0	234267.Acid_7841	2.418e-139	493.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4666934_1	234267.Acid_6671	2.124e-87	300.0	COG3872@1|root,COG3872@2|Bacteria,3Y66K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
YYD3_k127_4666934_0	240015.ACP_2651	2.83e-152	490.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria,2JHYH@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
YYD3_k127_4666934_3	204669.Acid345_4471	3.633e-65	234.0	COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria,2JJCF@204432|Acidobacteriia	204432|Acidobacteriia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
YYD3_k127_4666934_2	469383.Cwoe_4585	5.005e-74	257.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD3_k127_4666934_6	1267535.KB906767_gene1168	1.593e-25	122.0	COG0308@1|root,COG0308@2|Bacteria,3Y31F@57723|Acidobacteria,2JMCB@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
YYD3_k127_4666934_5	251221.35214315	1.572e-29	126.0	COG2197@1|root,COG2197@2|Bacteria,1G712@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_4666934_4	1173026.Glo7428_1925	2.666e-63	228.0	COG0265@1|root,COG0265@2|Bacteria,1G3YY@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_4670899_3	1267534.KB906755_gene4055	6.854e-143	464.0	COG1032@1|root,COG1032@2|Bacteria,3Y6NQ@57723|Acidobacteria,2JK90@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_4670899_2	682795.AciX8_3994	9.436e-177	568.0	COG1032@1|root,COG1032@2|Bacteria,3Y3GN@57723|Acidobacteria,2JI34@204432|Acidobacteriia	204432|Acidobacteriia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_4670899_1	1267533.KB906735_gene4594	8.374e-193	612.0	COG1032@1|root,COG1032@2|Bacteria,3Y3N8@57723|Acidobacteria,2JMAC@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_4670899_4	1267533.KB906735_gene4595	8.016e-63	226.0	COG0500@1|root,COG2226@2|Bacteria,3Y58M@57723|Acidobacteria,2JJRE@204432|Acidobacteriia	204432|Acidobacteriia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
YYD3_k127_4670899_0	1267534.KB906755_gene4050	1.097e-206	655.0	COG1032@1|root,COG1032@2|Bacteria,3Y2V1@57723|Acidobacteria,2JKBR@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_4670899_5	1198114.AciX9_0571	2.631e-35	147.0	COG0402@1|root,COG0500@1|root,COG0402@2|Bacteria,COG2226@2|Bacteria,3Y3KZ@57723|Acidobacteria,2JIXX@204432|Acidobacteriia	204432|Acidobacteriia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Methyltransf_11,Methyltransf_25
YYD3_k127_4701174_0	886293.Sinac_1153	8.875e-107	368.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4701174_1	204669.Acid345_3552	3.086e-71	259.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K03408,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,CheW,HATPase_c,HisKA,Methyltransf_11,Methyltransf_25,PAS_10,Response_reg
YYD3_k127_4701174_2	391625.PPSIR1_31553	1.474e-05	53.0	2ESCQ@1|root,33JXH@2|Bacteria,1P9JE@1224|Proteobacteria,4325U@68525|delta/epsilon subdivisions,2WXM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4706972_1	204669.Acid345_1678	1.26e-196	632.0	COG4932@1|root,COG4932@2|Bacteria,3Y98G@57723|Acidobacteria,2JP50@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4706972_0	204669.Acid345_1690	9.752e-270	839.0	COG0457@1|root,COG0457@2|Bacteria,3Y3MH@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_4706972_3	204669.Acid345_1691	3.979e-79	269.0	COG2197@1|root,COG2197@2|Bacteria,3Y4RA@57723|Acidobacteria,2JMRJ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_4706972_2	204669.Acid345_1692	8.254e-144	473.0	COG4585@1|root,COG4585@2|Bacteria,3Y3UD@57723|Acidobacteria,2JKVP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
YYD3_k127_4706972_4	240015.ACP_0438	1.282e-62	220.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YYD3_k127_4706972_7	395965.Msil_3485	1.316e-15	78.0	2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4706972_5	395965.Msil_3484	2.957e-37	146.0	COG4113@1|root,COG4113@2|Bacteria,1NEE2@1224|Proteobacteria,2UJ3R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_4706972_6	1267535.KB906767_gene5368	3.974e-24	106.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5368|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4707628_2	1125863.JAFN01000001_gene808	3.791e-187	598.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
YYD3_k127_4707628_6	1120949.KB903327_gene5326	3.694e-117	385.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4DACW@85008|Micromonosporales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
YYD3_k127_4707628_8	1120949.KB903327_gene5327	2.594e-108	362.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4D984@85008|Micromonosporales	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
YYD3_k127_4707628_4	1120950.KB892757_gene6486	2.732e-139	453.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DNHC@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
YYD3_k127_4707628_5	981369.JQMJ01000004_gene4221	5.987e-128	419.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,2NHPW@228398|Streptacidiphilus	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
YYD3_k127_4707628_3	1120949.KB903327_gene5330	4.511e-166	541.0	COG4166@1|root,COG4166@2|Bacteria,2IIU5@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_4707628_11	1267535.KB906767_gene846	1.372e-12	81.0	COG4796@1|root,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
YYD3_k127_4707628_9	234267.Acid_4171	6.643e-68	243.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_4707628_0	1242864.D187_004920	2.344e-231	725.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
YYD3_k127_4707628_10	1382306.JNIM01000001_gene1802	5.548e-27	113.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	nasE	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
YYD3_k127_4707628_7	497964.CfE428DRAFT_5848	7.177e-115	380.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4707628_1	497964.CfE428DRAFT_5849	1.916e-207	652.0	COG0243@1|root,COG0243@2|Bacteria,46U1H@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YYD3_k127_4722425_0	1211777.BN77_p11114	1.601e-67	246.0	COG2202@1|root,COG2984@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
YYD3_k127_4722425_1	1267535.KB906767_gene4110	1.151e-43	163.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
YYD3_k127_4724487_1	316274.Haur_0075	5.826e-22	105.0	COG1721@1|root,COG1721@2|Bacteria,2G7PU@200795|Chloroflexi,375DS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YYD3_k127_4724487_0	292459.STH463	2.232e-97	327.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD3_k127_4724487_2	292459.STH464	6.219e-11	74.0	2DS8I@1|root,33F02@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
YYD3_k127_4743965_1	234267.Acid_4307	1.096e-86	299.0	COG0551@1|root,COG0551@2|Bacteria,3Y7FR@57723|Acidobacteria	57723|Acidobacteria	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
YYD3_k127_4743965_2	1123242.JH636437_gene6120	2.642e-73	265.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_4743965_0	314230.DSM3645_24005	1.343e-94	325.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_4748779_5	234267.Acid_2265	2.617e-06	53.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
YYD3_k127_4748779_1	1267533.KB906736_gene1246	2.942e-57	213.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_4748779_0	671143.DAMO_2743	2.298e-59	209.0	COG1848@1|root,COG1848@2|Bacteria,2NRZ1@2323|unclassified Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_4748779_6	1550091.JROE01000002_gene475	2.531e-05	54.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CBM_6,F5_F8_type_C,PD40,SdrD_B
YYD3_k127_4748779_4	411154.GFO_0980	9.19e-15	79.0	COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4748779_2	1267535.KB906767_gene105	2.735e-38	158.0	COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YYD3_k127_4750647_1	234267.Acid_7352	1.222e-149	490.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07709,ko:K07710	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_10,PAS_4
YYD3_k127_4750647_0	234267.Acid_7351	1.424e-184	586.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_4750647_5	1128421.JAGA01000003_gene2958	3.443e-27	115.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_4750647_4	357808.RoseRS_3082	2.848e-79	286.0	COG3975@1|root,COG3975@2|Bacteria,2GAB7@200795|Chloroflexi,374W2@32061|Chloroflexia	32061|Chloroflexia	S	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
YYD3_k127_4750647_3	1089553.Tph_c17810	1.498e-80	276.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,42F0K@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
YYD3_k127_4750647_2	1267535.KB906767_gene4360	3.799e-136	450.0	COG1449@1|root,COG1449@2|Bacteria,3Y36M@57723|Acidobacteria,2JM7G@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
YYD3_k127_4753804_0	1121930.AQXG01000002_gene2002	2.504e-140	474.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1IP08@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
YYD3_k127_4769857_7	1210884.HG799465_gene11777	3.273e-26	113.0	COG0842@1|root,COG0842@2|Bacteria,2IY6D@203682|Planctomycetes	203682|Planctomycetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
YYD3_k127_4769857_1	1123508.JH636441_gene3666	7.853e-124	413.0	COG1131@1|root,COG1131@2|Bacteria,2IY2I@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_4769857_5	234267.Acid_5767	1.208e-54	204.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4769857_6	1173028.ANKO01000077_gene5317	1.1e-41	164.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Ribonuclease BN-like family	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
YYD3_k127_4769857_3	575540.Isop_0300	2.869e-110	375.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
YYD3_k127_4769857_4	443143.GM18_1188	1.502e-72	254.0	COG0564@1|root,COG0564@2|Bacteria,1MX5Y@1224|Proteobacteria,42R6V@68525|delta/epsilon subdivisions,2WMX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Pseudouridine synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
YYD3_k127_4769857_0	278957.ABEA03000135_gene1781	5.353e-302	947.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
YYD3_k127_4769857_2	886293.Sinac_4912	6.641e-115	376.0	COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes	203682|Planctomycetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_4775196_4	204669.Acid345_1029	2.173e-29	126.0	2DMGW@1|root,32REM@2|Bacteria,3Y4XX@57723|Acidobacteria,2JJER@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
YYD3_k127_4775196_5	234267.Acid_0789	9.807e-29	131.0	COG3595@1|root,COG3595@2|Bacteria,3Y3K3@57723|Acidobacteria	57723|Acidobacteria	C	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
YYD3_k127_4775196_7	1267535.KB906767_gene2973	9.259e-15	81.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4775196_0	1121382.JQKG01000012_gene236	3.282e-127	414.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
YYD3_k127_4775196_3	1499967.BAYZ01000065_gene6089	8.211e-69	239.0	COG1896@1|root,COG1896@2|Bacteria	2|Bacteria	S	5'-deoxynucleotidase activity	maf	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
YYD3_k127_4775196_6	1353529.M899_0646	2.728e-25	108.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_4775196_2	234267.Acid_3571	2.07e-70	245.0	COG0558@1|root,COG0558@2|Bacteria,3Y4PW@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
YYD3_k127_4775196_1	1192034.CAP_7016	3.551e-110	368.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
YYD3_k127_4811141_3	400682.PAC_15706812	1.427e-37	163.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	ko:K15503,ko:K21440	-	-	-	-	ko00000,ko01009,ko03400,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_4811141_2	29540.C481_00055	5.867e-43	161.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
YYD3_k127_4811141_1	1156919.QWC_00725	1.137e-86	300.0	COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2VRVM@28216|Betaproteobacteria,3T1H7@506|Alcaligenaceae	28216|Betaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
YYD3_k127_4811141_0	886293.Sinac_1153	1.665e-129	430.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4818664_3	903818.KI912269_gene367	7.854e-60	213.0	COG1704@1|root,COG1704@2|Bacteria,3Y4QG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
YYD3_k127_4818664_1	489825.LYNGBM3L_37480	5.888e-118	419.0	COG1752@1|root,COG1752@2|Bacteria,1G3GK@1117|Cyanobacteria,1H9DS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
YYD3_k127_4818664_5	266117.Rxyl_2043	1.472e-41	154.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
YYD3_k127_4818664_6	926692.AZYG01000051_gene1851	2.785e-38	160.0	COG1668@1|root,COG1668@2|Bacteria,1W74I@1239|Firmicutes,25MB4@186801|Clostridia,3WC5H@53433|Halanaerobiales	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2
YYD3_k127_4818664_2	382464.ABSI01000020_gene339	1.013e-74	259.0	COG4555@1|root,COG4555@2|Bacteria	2|Bacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	iYO844.BSU02750	ABC_tran
YYD3_k127_4818664_4	459349.CLOAM0956	8.345e-44	182.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,2NPVM@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992,ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	iYO844.BSU02760	ABC2_membrane_2,ABC2_membrane_3,Abi
YYD3_k127_4818664_0	64471.sync_2679	2.407e-139	460.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
YYD3_k127_4818664_7	1267535.KB906767_gene784	2.018e-26	115.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4834749_1	234267.Acid_7208	2.751e-53	202.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_4834749_2	240015.ACP_1525	7.985e-32	127.0	COG1695@1|root,COG1695@2|Bacteria,3Y5BK@57723|Acidobacteria,2JJRQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_4834749_0	97096.XP_007790920.1	2.137e-66	231.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_4862726_4	1218108.KB908295_gene1904	4.608e-18	87.0	COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,1HX7Q@117743|Flavobacteriia	976|Bacteroidetes	KT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
YYD3_k127_4862726_6	1408433.JHXV01000005_gene2290	3.145e-09	63.0	COG1729@1|root,COG1729@2|Bacteria,4PMDU@976|Bacteroidetes,1IKE6@117743|Flavobacteriia,2PB2R@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
YYD3_k127_4862726_5	5059.CADAFLAP00011758	1.344e-16	89.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_3
YYD3_k127_4862726_3	1173022.Cri9333_3521	6.413e-41	154.0	COG0745@1|root,COG0745@2|Bacteria,1G76E@1117|Cyanobacteria,1HBQR@1150|Oscillatoriales	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
YYD3_k127_4862726_0	861299.J421_5917	6.281e-162	531.0	COG0643@1|root,COG0643@2|Bacteria,1ZTCI@142182|Gemmatimonadetes	2|Bacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA5	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
YYD3_k127_4862726_2	1173028.ANKO01000214_gene6279	3.227e-49	181.0	COG0835@1|root,COG0835@2|Bacteria,1G7FI@1117|Cyanobacteria,1HBXN@1150|Oscillatoriales	1117|Cyanobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
YYD3_k127_4862726_1	1173028.ANKO01000214_gene6278	7.772e-97	336.0	COG0840@1|root,COG0840@2|Bacteria,1G4MY@1117|Cyanobacteria,1HA77@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
YYD3_k127_4866393_1	1340493.JNIF01000003_gene3475	6.317e-106	362.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_4866393_0	234267.Acid_5827	5.632e-207	671.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4866393_2	234267.Acid_5825	1.873e-64	241.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
YYD3_k127_4887808_3	1041146.ATZB01000046_gene9	2.377e-66	229.0	2A74D@1|root,30W03@2|Bacteria,1RBK6@1224|Proteobacteria,2U5R3@28211|Alphaproteobacteria,4BHEQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4887808_1	1298858.AUEL01000024_gene361	1.922e-208	656.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,43JXC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
YYD3_k127_4887808_0	420324.KI912082_gene6957	1.636e-232	729.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,1JUZ2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
YYD3_k127_4887808_4	153496.JNAB01000054_gene1091	3.681e-08	56.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2TW6Y@28211|Alphaproteobacteria,2JRIK@204441|Rhodospirillales	204441|Rhodospirillales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Thioredoxin_8
YYD3_k127_4887808_2	1380355.JNIJ01000016_gene5743	3.169e-149	474.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2TSCE@28211|Alphaproteobacteria,3JSZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
YYD3_k127_4902217_0	1385515.N791_01970	1.034e-93	312.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	tptC	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_4902217_2	204669.Acid345_3344	9.775e-61	220.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
YYD3_k127_4902217_1	204669.Acid345_3344	2.384e-67	240.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
YYD3_k127_4902217_3	240015.ACP_1809	1.944e-56	202.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
YYD3_k127_4908768_0	234267.Acid_5827	7.986e-230	731.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_4908768_1	886293.Sinac_1154	3.571e-117	391.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_4908768_2	1340493.JNIF01000004_gene918	2.369e-65	245.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
YYD3_k127_4908768_4	1248916.ANFY01000010_gene335	6.059e-22	105.0	COG2010@1|root,COG2010@2|Bacteria,1NBIA@1224|Proteobacteria,2UHSH@28211|Alphaproteobacteria,2KEUQ@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_4908768_3	395965.Msil_0410	2.162e-41	161.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_4927410_0	472759.Nhal_2900	0.0	1359.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
YYD3_k127_4927410_3	323261.Noc_1255	1.82e-125	421.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_4927410_1	234267.Acid_3959	4.209e-191	610.0	COG2982@1|root,COG2982@2|Bacteria,3Y2ZX@57723|Acidobacteria	57723|Acidobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
YYD3_k127_4927410_7	247633.GP2143_17801	4.135e-19	93.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4927410_2	63737.Npun_F2132	7.226e-182	577.0	COG4941@1|root,COG4941@2|Bacteria,1G1YQ@1117|Cyanobacteria,1HRSK@1161|Nostocales	1117|Cyanobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_4927410_4	234267.Acid_5299	1.87e-53	191.0	COG3795@1|root,COG3795@2|Bacteria,3Y5F1@57723|Acidobacteria	57723|Acidobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_4927410_5	1267535.KB906767_gene647	6.467e-50	190.0	COG2764@1|root,COG2764@2|Bacteria,3Y5JW@57723|Acidobacteria,2JK34@204432|Acidobacteriia	204432|Acidobacteriia	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
YYD3_k127_4927410_6	399739.Pmen_2136	5.54e-30	125.0	COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,1S480@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
YYD3_k127_493660_7	497964.CfE428DRAFT_0069	1.514e-10	63.0	2DP8B@1|root,330ZV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_493660_3	1122176.KB903531_gene2954	1.246e-43	172.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,PrcB_C,Prenyltrans,SLH,SQHop_cyclase_C
YYD3_k127_493660_5	136993.KB900627_gene392	4.134e-29	128.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_493660_4	136993.KB900627_gene391	1.715e-30	125.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_493660_2	1242864.D187_004225	6.018e-56	205.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria	1224|Proteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	attM	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_493660_1	234267.Acid_3837	6.794e-63	238.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_493660_6	1123508.JH636441_gene3102	5.23e-16	87.0	COG4099@1|root,COG4099@2|Bacteria,2IZGJ@203682|Planctomycetes	203682|Planctomycetes	M	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Peptidase_S9
YYD3_k127_493660_0	498211.CJA_0487	2.585e-76	267.0	COG3211@1|root,COG3211@2|Bacteria,1QY0R@1224|Proteobacteria,1S13A@1236|Gammaproteobacteria,1FHEH@10|Cellvibrio	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839,TAT_signal
YYD3_k127_4942726_1	622637.KE124772_gene56	7.672e-22	111.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2TRQ1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
YYD3_k127_4942726_2	1123258.AQXZ01000018_gene454	6.429e-13	78.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4G0AJ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4942726_0	1379270.AUXF01000002_gene1148	3.313e-29	121.0	COG4993@1|root,COG4993@2|Bacteria,1ZSSJ@142182|Gemmatimonadetes	2|Bacteria	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_4954968_1	314230.DSM3645_13770	6.131e-53	195.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_4954968_0	1123242.JH636434_gene4336	6.313e-94	312.0	COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes	203682|Planctomycetes	C	COG1012 NAD-dependent aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YYD3_k127_4954968_2	1123242.JH636434_gene4336	1.03e-28	116.0	COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes	203682|Planctomycetes	C	COG1012 NAD-dependent aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
YYD3_k127_4956916_1	234267.Acid_3114	9.026e-71	248.0	COG0642@1|root,COG2205@2|Bacteria	234267.Acid_3114|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4956916_0	234267.Acid_3115	4.047e-159	516.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria	57723|Acidobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
YYD3_k127_4959999_2	485918.Cpin_6495	3.726e-27	113.0	2ECYW@1|root,32WQ9@2|Bacteria,4NUET@976|Bacteroidetes,1IWGJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4959999_1	556268.OFAG_00222	6.865e-39	149.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,474U5@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
YYD3_k127_4959999_0	497964.CfE428DRAFT_3394	2.69e-133	435.0	COG0275@1|root,COG0275@2|Bacteria,46UK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	MraW methylase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_5
YYD3_k127_4959999_3	1550091.JROE01000013_gene221	1.791e-21	107.0	COG0702@1|root,COG0702@2|Bacteria,4NHVQ@976|Bacteroidetes,1IW87@117747|Sphingobacteriia	976|Bacteroidetes	GM	Starch-binding associating with outer membrane	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
YYD3_k127_49774_1	1121930.AQXG01000003_gene2498	8.331e-191	608.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1INX4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
YYD3_k127_49774_0	1382359.JIAL01000001_gene175	0.0	1247.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria,2JIA9@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
YYD3_k127_49774_4	243231.GSU1402	2.502e-105	347.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,43UDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
YYD3_k127_49774_7	234267.Acid_6292	3.107e-47	177.0	COG3127@1|root,COG3127@2|Bacteria,3Y7ZT@57723|Acidobacteria	57723|Acidobacteria	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_49774_11	1267535.KB906767_gene2392	1.724e-36	141.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
YYD3_k127_49774_9	713586.KB900536_gene1140	9.02e-42	158.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
YYD3_k127_49774_15	1215343.B488_03510	2.158e-05	55.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,4B7PV@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
YYD3_k127_49774_10	204669.Acid345_0591	3.267e-39	157.0	COG2885@1|root,COG2885@2|Bacteria,3Y3ZY@57723|Acidobacteria,2JI9Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
YYD3_k127_49774_5	204669.Acid345_0592	4.638e-91	315.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria,2JIV3@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
YYD3_k127_49774_14	240015.ACP_0503	5.292e-19	96.0	COG0810@1|root,COG0810@2|Bacteria,3Y4WH@57723|Acidobacteria,2JJSC@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
YYD3_k127_49774_13	204669.Acid345_0594	2.315e-31	127.0	COG0848@1|root,COG0848@2|Bacteria,3Y4QV@57723|Acidobacteria,2JJ9P@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
YYD3_k127_49774_8	401053.AciPR4_1997	4.957e-44	168.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria,2JIN7@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
YYD3_k127_49774_2	1121918.ARWE01000001_gene1055	1.459e-120	406.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,43S1R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RecF/RecN/SMC N terminal domain	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
YYD3_k127_49774_6	234267.Acid_6705	5.138e-67	231.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria	57723|Acidobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
YYD3_k127_49774_16	1262915.BN574_00483	0.0009762	49.0	2DXQ1@1|root,345Y4@2|Bacteria,1W1ES@1239|Firmicutes,4H85K@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_49774_3	582515.KR51_00036660	1.437e-117	391.0	COG0408@1|root,COG0408@2|Bacteria,1G1PA@1117|Cyanobacteria	1117|Cyanobacteria	H	Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
YYD3_k127_49774_12	330214.NIDE4254	6.433e-36	143.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
YYD3_k127_4983308_3	1242864.D187_009225	2.049e-09	64.0	2EICH@1|root,33C3T@2|Bacteria,1P6R7@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3060
YYD3_k127_4983308_2	882.DVU_3344	1.712e-17	94.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YYD3_k127_4983308_0	366602.Caul_1138	1.048e-53	198.0	COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,2TTXQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	GntR family	MA20_45020	-	-	ko:K11475	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
YYD3_k127_4983308_1	234267.Acid_6647	4.458e-49	200.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_4988137_6	886293.Sinac_6369	8.241e-19	100.0	COG0551@1|root,COG0551@2|Bacteria,2IXB2@203682|Planctomycetes	203682|Planctomycetes	L	Ca-dependent carbohydrate-binding module xylan-binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
YYD3_k127_4988137_4	379066.GAU_0831	5.119e-29	127.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4988137_8	234267.Acid_1525	7.101e-08	63.0	COG4932@1|root,COG4932@2|Bacteria,3Y53F@57723|Acidobacteria	57723|Acidobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4988137_7	204669.Acid345_2892	2.003e-08	61.0	COG4932@1|root,COG4932@2|Bacteria,3Y5W1@57723|Acidobacteria,2JNVI@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_4988137_5	1170562.Cal6303_1253	3.465e-22	102.0	COG1487@1|root,COG1487@2|Bacteria,1G736@1117|Cyanobacteria,1HSR1@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_4988137_2	1267535.KB906767_gene928	7.457e-48	191.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
YYD3_k127_4988137_0	338963.Pcar_2866	1.272e-197	627.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,43UNQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
YYD3_k127_4988137_1	583355.Caka_2913	4.296e-60	214.0	COG3005@1|root,COG3005@2|Bacteria,46T0N@74201|Verrucomicrobia,3K8D9@414999|Opitutae	414999|Opitutae	C	TIGRFAM cytochrome c nitrate reductase, small subunit	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
YYD3_k127_4988137_3	555793.WSK_1941	1.489e-29	125.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_4990707_11	1267535.KB906767_gene623	6.794e-41	164.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_4990707_10	330214.NIDE4022	4.26e-41	155.0	COG0633@1|root,COG0633@2|Bacteria,3J1AM@40117|Nitrospirae	40117|Nitrospirae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
YYD3_k127_4990707_6	234267.Acid_4090	3.283e-64	227.0	COG1187@1|root,COG1187@2|Bacteria,3Y6Y9@57723|Acidobacteria	57723|Acidobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
YYD3_k127_4990707_12	204669.Acid345_4103	1.305e-39	158.0	COG1496@1|root,COG1496@2|Bacteria,3Y3J1@57723|Acidobacteria,2JHKU@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
YYD3_k127_4990707_14	1131269.AQVV01000001_gene1326	2.458e-30	123.0	COG0736@1|root,COG0736@2|Bacteria	2|Bacteria	I	holo-[acyl-carrier-protein] synthase activity	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
YYD3_k127_4990707_2	1131462.DCF50_p2561	5.563e-87	304.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25ZY0@186807|Peptococcaceae	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
YYD3_k127_4990707_0	555088.DealDRAFT_1872	6.099e-130	427.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42JIT@68298|Syntrophomonadaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
YYD3_k127_4990707_3	1262449.CP6013_3880	3.638e-83	285.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,36DE3@31979|Clostridiaceae	186801|Clostridia	S	TIGRFAM TIGR00268 family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
YYD3_k127_4990707_5	330214.NIDE2766	8.717e-74	251.0	COG1403@1|root,COG1403@2|Bacteria,3J0VM@40117|Nitrospirae	40117|Nitrospirae	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
YYD3_k127_4990707_13	204669.Acid345_0104	3.695e-36	142.0	COG1610@1|root,COG1610@2|Bacteria,3Y4VF@57723|Acidobacteria,2JJJH@204432|Acidobacteriia	204432|Acidobacteriia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
YYD3_k127_4990707_9	1267535.KB906767_gene495	4.839e-45	175.0	COG0681@1|root,COG0681@2|Bacteria,3Y40D@57723|Acidobacteria,2JHWM@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
YYD3_k127_4990707_1	1340493.JNIF01000003_gene3319	2.169e-119	391.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD3_k127_4990707_4	370438.PTH_0066	1.38e-79	273.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,260K0@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
YYD3_k127_4990707_7	426117.M446_1294	3.474e-48	179.0	COG0212@1|root,COG0212@2|Bacteria,1RAZI@1224|Proteobacteria,2U6UH@28211|Alphaproteobacteria,1JU5Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	5-FTHF_cyc-lig
YYD3_k127_4990707_8	1089551.KE386572_gene1324	1.835e-47	173.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,4BP8G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
YYD3_k127_4992407_7	1128421.JAGA01000003_gene3216	0.0001668	44.0	COG0438@1|root,COG0438@2|Bacteria,2NR53@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like domain	rgpA	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	DUF1972,Glyco_trans_1_4,Glycos_transf_1
YYD3_k127_4992407_1	706587.Desti_0471	2.153e-104	345.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria,2MQUJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
YYD3_k127_4992407_0	562970.Btus_0864	8.402e-131	426.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,279GJ@186823|Alicyclobacillaceae	91061|Bacilli	M	Male sterility protein	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
YYD3_k127_4992407_6	96561.Dole_2627	4.639e-21	103.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
YYD3_k127_4992407_3	234267.Acid_3938	3.116e-26	111.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_4992407_5	234267.Acid_5940	4.503e-26	111.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_4992407_2	234267.Acid_7441	2.623e-32	136.0	COG1216@1|root,COG1216@2|Bacteria,3Y7JI@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
YYD3_k127_4992407_4	1450694.BTS2_1891	3.381e-26	115.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,4HQF6@91061|Bacilli	91061|Bacilli	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_499313_2	661478.OP10G_2561	3.748e-21	102.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
YYD3_k127_499313_0	1229909.NSED_01725	6.36e-24	108.0	COG3979@1|root,COG5549@1|root,arCOG04994@2157|Archaea,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,PKD,PQQ_2
YYD3_k127_4996802_3	234267.Acid_5982	0.0002845	49.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_4996802_1	649747.HMPREF0083_01968	2.872e-108	368.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
YYD3_k127_4996802_2	1267533.KB906737_gene1627	1.134e-33	135.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria,2JJRG@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
YYD3_k127_4996802_0	1123508.JH636443_gene4886	4.8e-209	657.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
YYD3_k127_5009152_5	1123508.JH636443_gene4841	6.988e-21	105.0	COG3324@1|root,COG3324@2|Bacteria,2J4IN@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_5009152_3	1128421.JAGA01000003_gene3304	3.095e-71	256.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
YYD3_k127_5009152_1	667014.Thein_1915	2.401e-146	474.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
YYD3_k127_5009152_4	234267.Acid_6723	5.582e-66	234.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
YYD3_k127_5009152_2	240015.ACP_1372	2.073e-123	404.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD3_k127_5009152_0	443143.GM18_1900	5.633e-177	568.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
YYD3_k127_5009152_6	1200792.AKYF01000012_gene1052	9.444e-21	97.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,26RX8@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
YYD3_k127_5014387_4	1267534.KB906754_gene3511	2.399e-58	206.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria	57723|Acidobacteria	L	5'-3' exonuclease, N-terminal resolvase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
YYD3_k127_5014387_9	240015.ACP_2551	3.876e-23	104.0	COG2975@1|root,COG2975@2|Bacteria,3Y5I4@57723|Acidobacteria,2JJZY@204432|Acidobacteriia	204432|Acidobacteriia	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
YYD3_k127_5014387_0	1267535.KB906767_gene195	9.948e-211	671.0	COG0443@1|root,COG0443@2|Bacteria,3Y2F8@57723|Acidobacteria,2JIVF@204432|Acidobacteriia	204432|Acidobacteriia	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
YYD3_k127_5014387_7	1382359.JIAL01000001_gene824	4.726e-30	125.0	COG1076@1|root,COG1076@2|Bacteria,3Y4MR@57723|Acidobacteria,2JJBF@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM heat shock protein DnaJ	-	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
YYD3_k127_5014387_6	204669.Acid345_0482	9.041e-33	131.0	COG0316@1|root,COG0316@2|Bacteria,3Y518@57723|Acidobacteria,2JJGN@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
YYD3_k127_5014387_3	1382359.JIAL01000001_gene822	1.809e-68	233.0	COG0822@1|root,COG0822@2|Bacteria,3Y4B9@57723|Acidobacteria,2JJ45@204432|Acidobacteriia	204432|Acidobacteriia	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YYD3_k127_5014387_1	1382359.JIAL01000001_gene821	1.159e-191	605.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD3_k127_5014387_8	1267535.KB906767_gene200	5.055e-30	126.0	COG1959@1|root,COG1959@2|Bacteria,3Y4X0@57723|Acidobacteria,2JJEV@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
YYD3_k127_5014387_2	1267534.KB906760_gene1427	1.383e-129	430.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_5014387_5	330214.NIDE1736	6.813e-47	177.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
YYD3_k127_502085_2	1144275.COCOR_07424	0.0002451	48.0	COG0810@1|root,COG4206@1|root,COG0810@2|Bacteria,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,43C8K@68525|delta/epsilon subdivisions,2X7IZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
YYD3_k127_502085_0	204669.Acid345_4182	7.644e-104	348.0	COG1600@1|root,COG1600@2|Bacteria,3Y3TQ@57723|Acidobacteria,2JHQQ@204432|Acidobacteriia	204432|Acidobacteriia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
YYD3_k127_502085_1	272123.Anacy_2102	5.921e-67	240.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1HIEF@1161|Nostocales	1117|Cyanobacteria	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
YYD3_k127_5029963_0	234267.Acid_6919	9.542e-200	637.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,3Y2SH@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
YYD3_k127_5029963_1	926566.Terro_0915	6.499e-57	205.0	2CGTC@1|root,331SF@2|Bacteria,3Y7P6@57723|Acidobacteria,2JMRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD3_k127_5057311_0	234267.Acid_7393	2.729e-129	432.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_5057311_4	234267.Acid_3661	0.0009181	45.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_5057311_2	1137271.AZUM01000001_gene1059	1.098e-10	68.0	2BRZD@1|root,32KZR@2|Bacteria,2HDNI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5057311_1	1184609.KILIM_092_00110	1.039e-31	129.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_5057311_3	1267533.KB906735_gene4668	3.088e-08	60.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_5088196_1	314230.DSM3645_24005	1.237e-79	284.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_5088196_0	216596.RL0064	1.477e-210	663.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2U1B2@28211|Alphaproteobacteria,4BBMJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
YYD3_k127_5096468_0	1232410.KI421424_gene1792	4.24e-178	569.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43TW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YYD3_k127_5096468_12	234267.Acid_5687	3.189e-32	127.0	COG0713@1|root,COG0713@2|Bacteria,3Y54E@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YYD3_k127_5096468_10	234267.Acid_5686	2.504e-40	155.0	COG0839@1|root,COG0839@2|Bacteria,3Y5QU@57723|Acidobacteria	57723|Acidobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YYD3_k127_5096468_6	1267535.KB906767_gene2816	4.661e-55	196.0	COG1143@1|root,COG1143@2|Bacteria,3Y529@57723|Acidobacteria,2JNAS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
YYD3_k127_5096468_2	671143.DAMO_2695	1.522e-116	385.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
YYD3_k127_5096468_1	204669.Acid345_1289	2.208e-172	547.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria,2JKWC@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
YYD3_k127_5096468_7	204669.Acid345_1288	4.989e-53	196.0	COG0852@1|root,COG0852@2|Bacteria,3Y5E8@57723|Acidobacteria,2JNBQ@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
YYD3_k127_5096468_5	237368.SCABRO_00950	3.806e-77	270.0	COG1565@1|root,COG1565@2|Bacteria,2J22U@203682|Planctomycetes	203682|Planctomycetes	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YYD3_k127_5096468_4	204669.Acid345_3358	5.638e-84	282.0	COG0377@1|root,COG0377@2|Bacteria,3Y3JS@57723|Acidobacteria,2JM3C@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
YYD3_k127_5096468_11	204669.Acid345_1287	3.707e-38	145.0	COG0838@1|root,COG0838@2|Bacteria,3Y59B@57723|Acidobacteria,2JNDX@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
YYD3_k127_5096468_9	1121423.JONT01000006_gene2431	7.866e-44	164.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,261XV@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
YYD3_k127_5096468_8	240015.ACP_1845	8.978e-50	184.0	COG0315@1|root,COG0315@2|Bacteria,3Y4IY@57723|Acidobacteria,2JJ7K@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
YYD3_k127_5096468_3	204669.Acid345_4646	2.39e-86	298.0	COG0303@1|root,COG0303@2|Bacteria,3Y3F0@57723|Acidobacteria,2JICE@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
YYD3_k127_5112992_1	234267.Acid_7841	7.811e-92	334.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_5112992_0	234267.Acid_5375	4.434e-96	333.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5112992_6	1239962.C943_03564	6.693e-21	108.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_5112992_2	1479237.JMLY01000001_gene3205	8.147e-44	172.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,468WK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
YYD3_k127_5112992_3	195250.CM001776_gene1121	8.817e-43	177.0	COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria,1H175@1129|Synechococcus	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5112992_10	1340493.JNIF01000003_gene2122	1.499e-09	64.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5112992_5	1335760.ASTG01000003_gene1745	7.187e-26	112.0	2CBAE@1|root,32T11@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5112992_9	555793.WSK_2874	4.991e-12	72.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5112992_8	1340493.JNIF01000003_gene2123	1.184e-20	101.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5112992_4	69395.JQLZ01000005_gene3645	1.656e-28	126.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5141236_1	1340493.JNIF01000003_gene4529	8.529e-13	76.0	COG3485@1|root,COG3485@2|Bacteria,3Y3FU@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5141236_0	926566.Terro_0915	2.876e-45	167.0	2CGTC@1|root,331SF@2|Bacteria,3Y7P6@57723|Acidobacteria,2JMRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD3_k127_5148301_5	240015.ACP_1370	3.849e-52	188.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_5148301_3	396588.Tgr7_3156	1.39e-94	323.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
YYD3_k127_5148301_2	485913.Krac_9360	4.036e-139	449.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
YYD3_k127_5148301_1	485913.Krac_9359	5.759e-158	504.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
YYD3_k127_5148301_4	1382306.JNIM01000001_gene2426	7.515e-88	304.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
YYD3_k127_5148301_0	1380394.JADL01000002_gene1394	9.742e-191	604.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,2JT4J@204441|Rhodospirillales	204441|Rhodospirillales	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
YYD3_k127_5162973_15	2850.Phatr48491	3.98e-05	49.0	COG1404@1|root,KOG1153@2759|Eukaryota,2XEIX@2836|Bacillariophyta	2759|Eukaryota	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
YYD3_k127_5162973_1	448385.sce5773	1.889e-175	556.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,43B0A@68525|delta/epsilon subdivisions,2X6EE@28221|Deltaproteobacteria,2YUMP@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	leuB2	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
YYD3_k127_5162973_9	1165096.ARWF01000001_gene433	1.614e-49	189.0	COG0607@1|root,COG3386@1|root,COG0607@2|Bacteria,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VHGN@28216|Betaproteobacteria,2KNEV@206350|Nitrosomonadales	206350|Nitrosomonadales	GP	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
YYD3_k127_5162973_5	880073.Calab_3575	2.848e-96	319.0	COG0745@1|root,COG0745@2|Bacteria,2NP9R@2323|unclassified Bacteria	2|Bacteria	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_5162973_4	404380.Gbem_2673	1.584e-99	346.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria,43VY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, HAMP domain-containing	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
YYD3_k127_5162973_8	1121920.AUAU01000010_gene123	1.526e-64	226.0	COG0231@1|root,COG0231@2|Bacteria,3Y2GH@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YYD3_k127_5162973_3	502025.Hoch_3263	2.088e-114	378.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YYCD@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD3_k127_5162973_12	234267.Acid_0107	5.957e-21	97.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_5162973_0	404380.Gbem_0834	1.508e-299	925.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
YYD3_k127_5162973_7	1128427.KB904821_gene174	2.453e-66	235.0	COG0705@1|root,COG0705@2|Bacteria,1G5IY@1117|Cyanobacteria,1HF1W@1150|Oscillatoriales	1117|Cyanobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD3_k127_5162973_2	935567.JAES01000029_gene2735	5.45e-125	406.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
YYD3_k127_5162973_10	1111728.ATYS01000005_gene909	3.006e-49	193.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1S0QP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
YYD3_k127_5162973_6	693661.Arcve_0555	3.076e-89	306.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,246VP@183980|Archaeoglobi	183980|Archaeoglobi	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
YYD3_k127_5162973_14	448385.sce4977	4.024e-07	52.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2YTWN@29|Myxococcales	28221|Deltaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
YYD3_k127_5162973_13	502025.Hoch_4773	4.946e-08	55.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1N34Y@1224|Proteobacteria,42TV3@68525|delta/epsilon subdivisions,2WQ5Z@28221|Deltaproteobacteria,2YUQ5@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
YYD3_k127_5162973_11	1122603.ATVI01000008_gene2289	1.444e-39	150.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,1S3IM@1236|Gammaproteobacteria,1XAJB@135614|Xanthomonadales	135614|Xanthomonadales	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
YYD3_k127_5186223_1	1267535.KB906767_gene3137	3.031e-73	262.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
YYD3_k127_5186223_6	1245469.S58_61530	9.527e-06	51.0	2AEKQ@1|root,314GF@2|Bacteria,1NAA2@1224|Proteobacteria,2UI5N@28211|Alphaproteobacteria,3K15I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
YYD3_k127_5186223_2	768671.ThimaDRAFT_3891	2.576e-66	242.0	COG1865@1|root,COG1865@2|Bacteria,1QYTY@1224|Proteobacteria,1RXYP@1236|Gammaproteobacteria,1WW8J@135613|Chromatiales	135613|Chromatiales	S	PFAM Adenosylcobinamide amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CbiZ
YYD3_k127_5186223_3	765910.MARPU_11780	5.113e-59	216.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1RN84@1236|Gammaproteobacteria,1WXAF@135613|Chromatiales	135613|Chromatiales	U	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
YYD3_k127_5186223_0	1077144.AGFF01000007_gene1680	1.404e-92	317.0	COG0614@1|root,COG0614@2|Bacteria,2IAFC@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
YYD3_k127_5186223_4	1170562.Cal6303_5214	3.384e-34	139.0	COG0609@1|root,COG0609@2|Bacteria,1G1KF@1117|Cyanobacteria,1HJ9C@1161|Nostocales	1117|Cyanobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
YYD3_k127_5195453_4	2903.EOD40718	8.842e-79	273.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
YYD3_k127_5195453_5	1121918.ARWE01000001_gene863	1.313e-68	250.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria,43S87@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
YYD3_k127_5195453_6	1267535.KB906767_gene5280	1.238e-42	162.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
YYD3_k127_5195453_7	497964.CfE428DRAFT_1693	1.438e-31	134.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
YYD3_k127_5195453_0	1382306.JNIM01000001_gene1966	1.898e-164	529.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
YYD3_k127_5195453_3	635013.TherJR_0912	1.115e-83	292.0	COG0006@1|root,COG0006@2|Bacteria,1TSXE@1239|Firmicutes,248AF@186801|Clostridia,2604W@186807|Peptococcaceae	186801|Clostridia	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
YYD3_k127_5195453_1	56780.SYN_00821	2.554e-132	428.0	COG1215@1|root,COG1215@2|Bacteria,1QV9Y@1224|Proteobacteria,43BP6@68525|delta/epsilon subdivisions,2X70H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_5195453_2	56780.SYN_00822	2.586e-104	345.0	COG0463@1|root,COG0463@2|Bacteria,1QV9Z@1224|Proteobacteria,43BP7@68525|delta/epsilon subdivisions,2X5F0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
YYD3_k127_5199435_3	204669.Acid345_1131	4.563e-173	549.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria,2JIRM@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
YYD3_k127_5199435_4	234267.Acid_2600	3.663e-111	367.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5199435_5	441769.ABFU01000042_gene3248	9.623e-48	185.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus	91061|Bacilli	O	membrane protein (homolog of Drosophila rhomboid)	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
YYD3_k127_5199435_2	203119.Cthe_1955	1.445e-186	616.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3WGWI@541000|Ruminococcaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
YYD3_k127_5199435_1	1267535.KB906767_gene605	1.066e-227	713.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,3Y2I9@57723|Acidobacteria,2JHNT@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
YYD3_k127_5199435_0	667014.Thein_1286	0.0	1100.0	COG0653@1|root,COG0653@2|Bacteria,2GGR1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
YYD3_k127_5203119_0	344747.PM8797T_05200	1.914e-247	781.0	COG1506@1|root,COG1506@2|Bacteria,2IXV8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
YYD3_k127_5203466_5	1047013.AQSP01000135_gene1606	2.245e-30	126.0	COG2893@1|root,COG2893@2|Bacteria,2NRCX@2323|unclassified Bacteria	2|Bacteria	G	PTS system fructose IIA component	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
YYD3_k127_5203466_6	1123228.AUIH01000002_gene1440	5.058e-11	66.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XKZ0@135619|Oceanospirillales	135619|Oceanospirillales	G	Phosphocarrier protein HPr	ptsO	-	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
YYD3_k127_5203466_2	1123274.KB899431_gene3256	2.122e-113	386.0	COG1080@1|root,COG1080@2|Bacteria,2J5FB@203691|Spirochaetes	203691|Spirochaetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
YYD3_k127_5203466_0	1382359.JIAL01000001_gene2783	6.988e-141	467.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
YYD3_k127_5203466_4	644966.Tmar_0912	4.051e-52	195.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WCKI@538999|Clostridiales incertae sedis	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
YYD3_k127_5203466_3	1125863.JAFN01000001_gene1800	1.027e-52	192.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
YYD3_k127_5203466_7	1382359.JIAL01000001_gene2780	4.314e-05	50.0	COG1758@1|root,COG1758@2|Bacteria,3Y5Z6@57723|Acidobacteria,2JK65@204432|Acidobacteriia	204432|Acidobacteriia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
YYD3_k127_5203466_1	204669.Acid345_3776	2.086e-120	398.0	COG0452@1|root,COG0452@2|Bacteria,3Y2QJ@57723|Acidobacteria,2JIK5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
YYD3_k127_5223383_5	204669.Acid345_0972	1.097e-21	100.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria,2JIR0@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
YYD3_k127_5223383_7	1050201.KB913034_gene998	2.72e-05	47.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,3VRJ8@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
YYD3_k127_5223383_8	338963.Pcar_1755	0.000679	52.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,42VYT@68525|delta/epsilon subdivisions,2WRFT@28221|Deltaproteobacteria,43T6X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_19,TPR_2,TPR_8
YYD3_k127_5223383_3	56780.SYN_01499	6.362e-51	194.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MQBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
YYD3_k127_5223383_2	338966.Ppro_2699	9.833e-57	209.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,42QS0@68525|delta/epsilon subdivisions,2WMU6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
YYD3_k127_5223383_0	1267533.KB906738_gene2058	1.521e-162	522.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria,2JHVJ@204432|Acidobacteriia	204432|Acidobacteriia	U	secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
YYD3_k127_5223383_4	323848.Nmul_A2355	5.834e-28	127.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2VNYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	U	pilus assembly protein	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
YYD3_k127_5223383_6	1121434.AULY01000009_gene2038	4.17e-18	96.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
YYD3_k127_5223383_1	1340493.JNIF01000003_gene3295	2.977e-105	358.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
YYD3_k127_5226064_7	1382359.JIAL01000001_gene1085	3.678e-13	80.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_5226064_5	234267.Acid_6219	8.409e-22	106.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_5226064_6	1340493.JNIF01000003_gene4251	7.594e-19	98.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
YYD3_k127_5226064_3	342949.PNA2_1950	9.119e-53	201.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota,242X5@183968|Thermococci	183968|Thermococci	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD3_k127_5226064_10	383372.Rcas_3764	0.0002817	52.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
YYD3_k127_5226064_4	204669.Acid345_2892	2.043e-37	160.0	COG4932@1|root,COG4932@2|Bacteria,3Y5W1@57723|Acidobacteria,2JNVI@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5226064_2	627192.SLG_25610	2.196e-69	240.0	COG4341@1|root,COG4341@2|Bacteria,1RAX5@1224|Proteobacteria,2U5RV@28211|Alphaproteobacteria,2KAD4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5226064_0	671143.DAMO_2457	3.246e-239	750.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD3_k127_5226064_11	446469.Sked_04060	0.000357	50.0	COG1716@1|root,COG1716@2|Bacteria,2GVTI@201174|Actinobacteria	201174|Actinobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
YYD3_k127_5226064_9	1047013.AQSP01000090_gene673	0.0001254	50.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
YYD3_k127_5226064_1	234267.Acid_1509	7.68e-132	438.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5226064_12	1198114.AciX9_2310	0.0007861	52.0	COG1629@1|root,COG1629@2|Bacteria,3Y9BI@57723|Acidobacteria,2JHTY@204432|Acidobacteriia	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_5226064_8	639030.JHVA01000001_gene183	4.981e-11	67.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
YYD3_k127_5226360_1	1242864.D187_000932	1.225e-19	95.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria	1224|Proteobacteria	G	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
YYD3_k127_5226360_2	1267535.KB906767_gene5028	1.745e-17	94.0	2DN1Y@1|root,32V1U@2|Bacteria,3Y5J2@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5226360_0	639030.JHVA01000001_gene2421	1.578e-38	147.0	COG1695@1|root,COG1695@2|Bacteria,3Y4ST@57723|Acidobacteria,2JJFA@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
YYD3_k127_5226360_3	1173026.Glo7428_2201	9.253e-09	64.0	28JE3@1|root,2Z98B@2|Bacteria,1G13G@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5226360_4	234267.Acid_4393	4.655e-06	57.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5229213_0	1122612.AUBA01000025_gene3129	6.779e-78	272.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2KCKC@204457|Sphingomonadales	204457|Sphingomonadales	J	Amidase	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
YYD3_k127_5229213_1	1396141.BATP01000018_gene1537	1.001e-16	86.0	2FI25@1|root,349V0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5234144_1	471853.Bcav_2721	2.823e-42	162.0	COG2334@1|root,COG2334@2|Bacteria,2IJNW@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
YYD3_k127_5234144_2	1296416.JACB01000054_gene3790	0.0002157	50.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia,2YH9R@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
YYD3_k127_5234144_0	234267.Acid_7841	5.871e-69	265.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_5245363_4	204669.Acid345_4505	2.86e-28	114.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria,2JJPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
YYD3_k127_5245363_2	234267.Acid_1167	9.725e-182	578.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
YYD3_k127_5245363_1	204669.Acid345_3065	1.296e-200	637.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
YYD3_k127_5245363_5	1142511.WIGMOR_0223	1.462e-11	73.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_1506	ADK,ADK_lid
YYD3_k127_5245363_6	378806.STAUR_0124	1.788e-05	55.0	28QQ1@1|root,2ZD5J@2|Bacteria,1QPY8@1224|Proteobacteria,439MX@68525|delta/epsilon subdivisions,2X4Z5@28221|Deltaproteobacteria,2YZVK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5245363_0	1267535.KB906767_gene2735	3.61e-238	747.0	COG4993@1|root,COG4993@2|Bacteria,3Y6HR@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_5245363_3	234267.Acid_6134	2.014e-81	280.0	COG2010@1|root,COG2010@2|Bacteria,3Y6RF@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_5263738_2	1304878.AUGD01000002_gene2255	1.189e-12	70.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2TQQR@28211|Alphaproteobacteria,3JTWJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,NB-ARC,TPR_4,Trans_reg_C
YYD3_k127_5263738_1	1333507.AUTQ01000193_gene4528	2.006e-33	144.0	COG0491@1|root,COG0491@2|Bacteria,1PBS8@1224|Proteobacteria,1RS4P@1236|Gammaproteobacteria,2Q09T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5263738_0	1239962.C943_04599	4.27e-69	245.0	COG0823@1|root,COG0823@2|Bacteria,4PI3V@976|Bacteroidetes,47VXF@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
YYD3_k127_5268145_0	234267.Acid_2629	3.565e-14	83.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5268145_1	1382359.JIAL01000001_gene2631	5.847e-10	71.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_527218_2	82508.K1VSQ2	2.801e-09	62.0	COG1143@1|root,KOG3256@2759|Eukaryota,38HK4@33154|Opisthokonta,3NVE7@4751|Fungi,3UZJ8@5204|Basidiomycota,3VDWS@5234|Tremellales	4751|Fungi	C	4Fe-4S dicluster domain	NdufS8	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3,1.6.99.3	ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Fer4
YYD3_k127_527218_0	330084.JNYZ01000008_gene6625	5.092e-77	272.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
YYD3_k127_527218_1	1381123.AYOD01000023_gene1474	8.932e-41	155.0	2DMP1@1|root,32SS8@2|Bacteria,1N0XZ@1224|Proteobacteria,2UBZ9@28211|Alphaproteobacteria,43JXR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3237)	MA20_18690	-	-	-	-	-	-	-	-	-	-	-	DUF3237
YYD3_k127_527218_3	1089547.KB913013_gene1393	1.513e-06	55.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5272596_0	472759.Nhal_2907	5.138e-99	349.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
YYD3_k127_5285175_0	861299.J421_1699	4.252e-228	719.0	COG2866@1|root,COG2866@2|Bacteria,1ZSQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
YYD3_k127_5285175_2	224325.AF_1469	9.682e-67	234.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2460M@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_5285175_1	269799.Gmet_1517	2.75e-153	515.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1NR2V@1224|Proteobacteria,42YIK@68525|delta/epsilon subdivisions,2WUNG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MV	MacB-like periplasmic core domain	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_5285175_3	443143.GM18_3937	2.057e-31	132.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,43VVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
YYD3_k127_5287742_3	1254432.SCE1572_15335	1.267e-06	53.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_5287742_2	1090318.ATTI01000001_gene970	1.507e-16	91.0	COG3258@1|root,COG3258@2|Bacteria,1R0F2@1224|Proteobacteria,2TYQH@28211|Alphaproteobacteria,2K6ZI@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_5287742_0	1123060.JONP01000012_gene2827	1.344e-112	374.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
YYD3_k127_5287742_1	97096.XP_007790920.1	5.016e-46	173.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_5297153_2	1007104.SUS17_2415	6.655e-45	173.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5297153_4	555793.WSK_3324	1.246e-16	85.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5297153_0	886293.Sinac_7544	1.631e-55	213.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2J4YH@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
YYD3_k127_5297153_3	234267.Acid_6753	3.443e-40	167.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,3Y4DW@57723|Acidobacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1,3.4.21.53	ko:K01338,ko:K04757,ko:K06379,ko:K08282,ko:K17752	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01002,ko03021	-	-	-	HATPase_c_2,HTH_8,Response_reg
YYD3_k127_5297153_1	1379270.AUXF01000004_gene3199	1.681e-52	194.0	COG3342@1|root,COG3342@2|Bacteria,1ZUFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
YYD3_k127_5297553_2	627192.SLG_25160	2.041e-54	203.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5297553_4	526227.Mesil_0178	9.274e-20	96.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
YYD3_k127_5297553_0	640511.BC1002_4609	9.532e-135	442.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VNKT@28216|Betaproteobacteria,1KGZG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_23,Methyltransf_25,Methyltransf_31
YYD3_k127_5297553_1	398527.Bphyt_7042	1.015e-91	313.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,1K52I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Methyltransferase	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
YYD3_k127_5297553_3	497964.CfE428DRAFT_1821	2.759e-32	132.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_5334932_1	861299.J421_1516	3.661e-77	264.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
YYD3_k127_5334932_0	234267.Acid_3898	6.275e-170	549.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
YYD3_k127_5342627_1	56780.SYN_00826	1.403e-53	194.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,NodS
YYD3_k127_5342627_0	1254432.SCE1572_16030	1.369e-115	384.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
YYD3_k127_5342627_2	1123072.AUDH01000009_gene463	1.183e-06	52.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2VFQZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_5350945_9	234267.Acid_2629	4.471e-11	68.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_5350945_10	314266.SKA58_08769	8.618e-06	52.0	COG0500@1|root,COG2226@2|Bacteria,1REUM@1224|Proteobacteria,2U75Q@28211|Alphaproteobacteria,2K51Q@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	ko:K13623	ko00564,map00564	-	R09073	RC00003,RC02308	ko00000,ko00001	-	-	-	Methyltransf_23,Methyltransf_25
YYD3_k127_5350945_2	497964.CfE428DRAFT_4359	3.63e-66	239.0	COG3000@1|root,COG3000@2|Bacteria,46W5T@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
YYD3_k127_5350945_5	1047013.AQSP01000052_gene2599	2.213e-33	145.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD3_k127_5350945_1	1121949.AQXT01000002_gene2531	5.483e-73	259.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TW40@28211|Alphaproteobacteria,440XV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
YYD3_k127_5350945_6	460265.Mnod_4794	2.512e-32	133.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2U2G6@28211|Alphaproteobacteria,1JUTG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
YYD3_k127_5350945_4	96561.Dole_2675	4.891e-39	156.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,2MHV7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
YYD3_k127_5350945_7	661478.OP10G_3699	3.668e-31	129.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
YYD3_k127_5350945_0	289376.THEYE_A0078	5.704e-98	331.0	COG1242@1|root,COG1242@2|Bacteria	2|Bacteria	K	4 iron, 4 sulfur cluster binding	yhcC	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
YYD3_k127_5350945_3	234267.Acid_2217	1.187e-50	189.0	COG0705@1|root,COG0705@2|Bacteria,3Y45U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
YYD3_k127_5354893_1	197221.22295478	1.831e-109	370.0	COG3975@1|root,COG3975@2|Bacteria,1G0YP@1117|Cyanobacteria	1117|Cyanobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
YYD3_k127_5354893_6	671143.DAMO_0141	1.041e-19	96.0	2EQC7@1|root,33HYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5354893_5	1144275.COCOR_03035	5.454e-25	113.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
YYD3_k127_5354893_3	1047013.AQSP01000128_gene418	3.017e-49	187.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
YYD3_k127_5354893_2	1379698.RBG1_1C00001G1510	4.092e-82	291.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD3_k127_5354893_0	1379698.RBG1_1C00001G1511	1.319e-155	510.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
YYD3_k127_5354893_4	215803.DB30_8025	2.58e-33	131.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
YYD3_k127_5358223_1	1267535.KB906767_gene2550	4.679e-203	644.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
YYD3_k127_5358223_0	640081.Dsui_3231	0.0	1720.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
YYD3_k127_5358223_2	204669.Acid345_1714	4.624e-125	415.0	COG1207@1|root,COG1207@2|Bacteria,3Y3SI@57723|Acidobacteria,2JIVK@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
YYD3_k127_5358223_3	1267535.KB906767_gene5312	4.865e-94	317.0	COG0391@1|root,COG0391@2|Bacteria,3Y3ZE@57723|Acidobacteria,2JITK@204432|Acidobacteriia	204432|Acidobacteriia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
YYD3_k127_5358223_9	204669.Acid345_2189	2.082e-15	85.0	COG0457@1|root,COG0457@2|Bacteria,3Y4XQ@57723|Acidobacteria,2JJFK@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_5358223_10	926561.KB900620_gene3039	5.419e-07	54.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia,3WAY7@53433|Halanaerobiales	186801|Clostridia	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
YYD3_k127_5358223_8	1469607.KK073768_gene3242	1.139e-33	147.0	COG2027@1|root,COG2027@2|Bacteria,1G06E@1117|Cyanobacteria,1HJQJ@1161|Nostocales	1117|Cyanobacteria	M	PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
YYD3_k127_5358223_6	1379270.AUXF01000001_gene2300	1.055e-40	163.0	29X7K@1|root,30IWU@2|Bacteria,1ZUTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_5358223_4	1191523.MROS_0061	3.372e-90	306.0	COG0506@1|root,COG0506@2|Bacteria	2|Bacteria	E	proline dehydrogenase activity	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
YYD3_k127_5358223_5	1173022.Cri9333_3922	2.489e-73	257.0	COG1234@1|root,COG1234@2|Bacteria,1G16X@1117|Cyanobacteria,1H9GB@1150|Oscillatoriales	1117|Cyanobacteria	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
YYD3_k127_5358223_7	323259.Mhun_0476	1.341e-36	143.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
YYD3_k127_5397275_2	1340493.JNIF01000003_gene4114	5.935e-39	152.0	COG1253@1|root,COG1253@2|Bacteria,3Y3MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
YYD3_k127_5397275_0	1449126.JQKL01000017_gene2744	1.539e-92	313.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,2680T@186813|unclassified Clostridiales	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
YYD3_k127_5397275_1	926562.Oweho_0806	9.883e-41	156.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1I4BI@117743|Flavobacteriia,2PBSI@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
YYD3_k127_5397275_4	1121948.AUAC01000004_gene92	2.668e-23	106.0	2DQKT@1|root,337HF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD3_k127_5397275_3	1405.DJ92_414	2.226e-34	143.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07471,ko:K13652,ko:K19056	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,DinB_2,GyrI-like,HTH_18
YYD3_k127_5397539_2	411465.PEPMIC_00075	3.135e-28	113.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,22HE2@1570339|Peptoniphilaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
YYD3_k127_5397539_1	240015.ACP_1455	3.394e-65	227.0	COG0049@1|root,COG0049@2|Bacteria,3Y3FF@57723|Acidobacteria,2JI5C@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
YYD3_k127_5397539_0	243231.GSU2860	0.0	1019.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
YYD3_k127_5397539_3	1267533.KB906734_gene3641	7.308e-16	77.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
YYD3_k127_5408438_4	1267534.KB906755_gene4057	1.009e-21	107.0	COG1493@1|root,COG1493@2|Bacteria,3Y4YI@57723|Acidobacteria,2JK5E@204432|Acidobacteriia	204432|Acidobacteriia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5408438_1	204669.Acid345_4055	4.219e-113	386.0	COG4191@1|root,COG4191@2|Bacteria,3Y4SZ@57723|Acidobacteria,2JK9S@204432|Acidobacteriia	204432|Acidobacteriia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_5408438_3	204669.Acid345_4054	7.055e-81	275.0	COG0745@1|root,COG0745@2|Bacteria,3Y4GX@57723|Acidobacteria,2JJ6P@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_5408438_6	1392502.JNIO01000008_gene3010	7.549e-11	74.0	COG3307@1|root,COG3307@2|Bacteria,1V4DY@1239|Firmicutes,4H4E3@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
YYD3_k127_5408438_0	682795.AciX8_0909	3.163e-246	768.0	COG1032@1|root,COG1032@2|Bacteria,3Y34B@57723|Acidobacteria,2JI2Z@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_5408438_5	1198114.AciX9_0577	3.712e-16	81.0	COG1032@1|root,COG1032@2|Bacteria,3Y6NQ@57723|Acidobacteria,2JK90@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
YYD3_k127_5420741_1	243090.RB8905	2.106e-125	408.0	COG1215@1|root,COG1215@2|Bacteria,2IZ7V@203682|Planctomycetes	203682|Planctomycetes	M	COG0463 Glycosyltransferases involved in cell wall	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
YYD3_k127_5420741_4	1403819.BATR01000122_gene4256	1.264e-62	222.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
YYD3_k127_5420741_2	596151.DesfrDRAFT_2348	4.647e-111	368.0	COG0451@1|root,COG0451@2|Bacteria,1PBJP@1224|Proteobacteria,43AUZ@68525|delta/epsilon subdivisions,2X692@28221|Deltaproteobacteria,2MADF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
YYD3_k127_5420741_0	1174528.JH992898_gene3803	3.98e-180	572.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
YYD3_k127_5420741_6	1198114.AciX9_1301	3.868e-24	118.0	COG1807@1|root,COG1807@2|Bacteria,3Y4VS@57723|Acidobacteria,2JK41@204432|Acidobacteriia	204432|Acidobacteriia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
YYD3_k127_5420741_7	1146883.BLASA_1767	4.901e-05	49.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5420741_5	28072.Nos7524_3271	1.851e-33	153.0	COG2374@1|root,COG2706@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3291@1|root,COG2374@2|Bacteria,COG2706@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,1GJ9G@1117|Cyanobacteria,1HR22@1161|Nostocales	1117|Cyanobacteria	QU	PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	DUF4347,Lactonase
YYD3_k127_5420741_3	489825.LYNGBM3L_47380	3.983e-89	337.0	COG2931@1|root,COG3386@1|root,COG4447@1|root,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,1G7BP@1117|Cyanobacteria,1HCF5@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
YYD3_k127_542333_0	204669.Acid345_3349	4.266e-124	413.0	COG0297@1|root,COG0297@2|Bacteria,3Y3IH@57723|Acidobacteria,2JHNU@204432|Acidobacteriia	204432|Acidobacteriia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
YYD3_k127_542333_1	316274.Haur_4037	2.182e-73	260.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
YYD3_k127_542333_2	671143.DAMO_0980	6.375e-32	127.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
YYD3_k127_5440819_0	880072.Desac_2891	7.842e-128	421.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MQ9H@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_5440819_4	234267.Acid_3520	3.49e-32	131.0	COG1595@1|root,COG1595@2|Bacteria,3Y5BF@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_5440819_8	204669.Acid345_4398	3.034e-06	53.0	2ERSC@1|root,33JBJ@2|Bacteria,3Y5XV@57723|Acidobacteria,2JK5S@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5440819_7	204669.Acid345_4399	3.21e-15	83.0	2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria,2JJU7@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
YYD3_k127_5440819_3	391037.Sare_4488	4.805e-58	209.0	COG1011@1|root,COG1011@2|Bacteria,2GPJ4@201174|Actinobacteria,4DAVQ@85008|Micromonosporales	201174|Actinobacteria	S	Had-superfamily hydrolase, subfamily ia, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase,Hydrolase_like
YYD3_k127_5440819_5	1123242.JH636434_gene5335	4.322e-32	129.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	2.3.2.29,2.5.1.18,3.8.1.2	ko:K00799,ko:K01560,ko:K21420	ko00361,ko00480,ko00625,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00625,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418	-	R03522,R05287,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11547,R11548,R11905	RC00004,RC00064,RC00069,RC00697,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
YYD3_k127_5440819_6	338969.Rfer_4021	7.613e-32	128.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2VJY9@28216|Betaproteobacteria,4AAK3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
YYD3_k127_5440819_1	234267.Acid_5981	6.96e-100	343.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_5440819_2	234267.Acid_4126	4.387e-67	242.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_5454309_2	1267535.KB906767_gene4753	7.657e-38	162.0	COG0419@1|root,COG0515@1|root,COG0419@2|Bacteria,COG0515@2|Bacteria	2|Bacteria	KLT	protein kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	AAA_15,AAA_21,DUF4339,TMP_2,Tubulin_2
YYD3_k127_5454309_1	269799.Gmet_1298	2.019e-42	171.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria,43W33@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
YYD3_k127_5454309_0	1123368.AUIS01000026_gene1471	6.502e-213	673.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,2NCBF@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
YYD3_k127_5454309_3	1340493.JNIF01000003_gene1982	5.125e-37	144.0	COG3127@1|root,COG3127@2|Bacteria,3Y2PA@57723|Acidobacteria	57723|Acidobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_5455927_0	1278073.MYSTI_03831	4.939e-42	160.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2YZBI@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
YYD3_k127_5455927_1	288000.BBta_3942	5.771e-41	156.0	COG1051@1|root,COG1051@2|Bacteria,1R7HG@1224|Proteobacteria,2TUSV@28211|Alphaproteobacteria,3JWGB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
YYD3_k127_5457734_2	1185652.USDA257_c15180	3.956e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1PQD2@1224|Proteobacteria,2U31T@28211|Alphaproteobacteria,4BD55@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_4,TPR_8
YYD3_k127_5457734_1	234267.Acid_0945	2.362e-13	78.0	COG1595@1|root,COG1595@2|Bacteria,3Y58Z@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
YYD3_k127_5457734_0	448385.sce3507	2.207e-128	430.0	COG0642@1|root,COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X791@28221|Deltaproteobacteria,2YUF6@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
YYD3_k127_5485971_0	1463934.JOCF01000077_gene6520	7.18e-28	123.0	COG0500@1|root,COG2226@2|Bacteria,2H1GK@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
YYD3_k127_5485971_1	401053.AciPR4_1653	1.319e-21	98.0	COG3682@1|root,COG3682@2|Bacteria,3Y4ZW@57723|Acidobacteria,2JJI5@204432|Acidobacteriia	204432|Acidobacteriia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_5485971_2	1267535.KB906767_gene3906	4.783e-12	75.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,3Y8M9@57723|Acidobacteria	57723|Acidobacteria	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
YYD3_k127_5504356_3	682795.AciX8_1432	2.723e-99	331.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
YYD3_k127_5504356_0	204669.Acid345_0710	5.985e-135	443.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria,2JMAK@204432|Acidobacteriia	204432|Acidobacteriia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
YYD3_k127_5504356_5	1267534.KB906761_gene1205	1.005e-12	79.0	29QWH@1|root,33RCM@2|Bacteria,3Y72V@57723|Acidobacteria,2JMFU@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5504356_2	204669.Acid345_1153	1.419e-103	357.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
YYD3_k127_5504356_4	1499967.BAYZ01000115_gene2925	9.518e-35	142.0	COG0741@1|root,COG0741@2|Bacteria,2NPR5@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23,PhageMin_Tail,Rod-binding,SLT,TrbL,VanY
YYD3_k127_5504356_1	671143.DAMO_1329	4.008e-123	409.0	COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD3_k127_5507755_1	344747.PM8797T_06150	1.252e-84	294.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5507755_2	29486.NJ56_02080	2.599e-58	210.0	COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,1RPY6@1236|Gammaproteobacteria,41EAS@629|Yersinia	1236|Gammaproteobacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ytfE	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564	-	ko:K07322	-	-	-	-	ko00000	-	-	iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820	Hemerythrin,ScdA_N
YYD3_k127_5507755_0	1123487.KB892834_gene3027	2.284e-136	449.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2VJYJ@28216|Betaproteobacteria,2KY1N@206389|Rhodocyclales	206389|Rhodocyclales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
YYD3_k127_5542572_0	349741.Amuc_0681	1.27e-124	413.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,2ITID@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mur ligase family, catalytic domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD3_k127_5542572_2	426114.THI_1455	1.566e-05	52.0	2EIG1@1|root,33C7D@2|Bacteria,1NNA9@1224|Proteobacteria,2W607@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5542572_1	323259.Mhun_1622	4.708e-29	123.0	COG0693@1|root,arCOG00769@2157|Archaea,2XTPH@28890|Euryarchaeota,2N9U0@224756|Methanomicrobia	224756|Methanomicrobia	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YYD3_k127_5542572_3	446471.Xcel_3238	6.446e-05	47.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4F420@85017|Promicromonosporaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD3_k127_5546858_0	1210884.HG799464_gene10528	1.442e-215	676.0	COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes	203682|Planctomycetes	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
YYD3_k127_5546858_1	756272.Plabr_2035	2.289e-92	317.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_5546858_2	497964.CfE428DRAFT_5031	2.899e-48	176.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_5556017_2	555793.WSK_2875	3.317e-05	47.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5556017_0	589873.EP13_13630	3.445e-26	120.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5559196_3	1121904.ARBP01000007_gene2888	1.508e-147	484.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_5559196_2	211165.AJLN01000116_gene3124	8.731e-152	492.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase
YYD3_k127_5559196_4	1192034.CAP_0368	2.935e-67	239.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,4307J@68525|delta/epsilon subdivisions,2WV6F@28221|Deltaproteobacteria,2YVCQ@29|Myxococcales	28221|Deltaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_5559196_1	243090.RB9498	2.863e-283	874.0	COG3119@1|root,COG3119@2|Bacteria,2IYIB@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YYD3_k127_5559196_0	522373.Smlt2488	0.0	1115.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,1TBUW@1236|Gammaproteobacteria,1XBTY@135614|Xanthomonadales	135614|Xanthomonadales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
YYD3_k127_5568715_11	1157708.KB907452_gene3975	6.603e-31	122.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VIEI@28216|Betaproteobacteria,4AARS@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.2.1.43,4.3.3.7	ko:K01714,ko:K13876	ko00053,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02278,R10147	RC00429,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YYD3_k127_5568715_1	497964.CfE428DRAFT_0590	3.08e-187	602.0	COG1012@1|root,COG1012@2|Bacteria,46SIA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD3_k127_5568715_7	379066.GAU_2821	2.952e-58	217.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5568715_10	247633.GP2143_13056	2.137e-31	136.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5568715_3	323261.Noc_2290	4.494e-91	304.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1WY52@135613|Chromatiales	135613|Chromatiales	C	Reduction of activated sulfate into sulfite	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
YYD3_k127_5568715_2	398578.Daci_3128	7.983e-142	459.0	COG3485@1|root,COG3485@2|Bacteria,1QBMH@1224|Proteobacteria,2VIH6@28216|Betaproteobacteria,4ADJ8@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Catechol dioxygenase N terminus	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
YYD3_k127_5568715_0	266117.Rxyl_1565	2.014e-198	629.0	COG0404@1|root,COG0404@2|Bacteria,2GPU4@201174|Actinobacteria,4CRTT@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM glycine cleavage T protein (aminomethyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
YYD3_k127_5568715_8	298654.FraEuI1c_4104	5.741e-46	185.0	28JDP@1|root,32SV2@2|Bacteria,2IPQY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5568715_13	1192034.CAP_8221	8.553e-15	87.0	2C9T2@1|root,347D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5568715_4	857087.Metme_2463	1.966e-80	277.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
YYD3_k127_5568715_6	1122929.KB908215_gene1030	1.024e-59	210.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Peroxiredoxin	MA20_20905	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
YYD3_k127_5568715_9	439292.Bsel_0658	4.781e-35	143.0	COG2114@1|root,COG2114@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli	91061|Bacilli	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YYD3_k127_5577879_12	1267535.KB906767_gene829	2.258e-57	220.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
YYD3_k127_5577879_1	1209989.TepiRe1_1179	2.534e-172	557.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,42EZN@68295|Thermoanaerobacterales	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
YYD3_k127_5577879_9	1267535.KB906767_gene780	1.215e-67	234.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria,2JIEA@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
YYD3_k127_5577879_8	1379698.RBG1_1C00001G1631	1.736e-83	292.0	COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria	2|Bacteria	E	Metallopeptidase family M24	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
YYD3_k127_5577879_7	1382359.JIAL01000001_gene2314	7.597e-93	316.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria,2JIHD@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
YYD3_k127_5577879_3	1340493.JNIF01000003_gene1816	4.895e-137	443.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	He_PIG,NHL,SGL
YYD3_k127_5577879_6	204669.Acid345_1347	1.896e-94	317.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
YYD3_k127_5577879_2	234267.Acid_7718	3.247e-161	536.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
YYD3_k127_5577879_4	1340493.JNIF01000003_gene4687	5.716e-107	369.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria	57723|Acidobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
YYD3_k127_5577879_0	240015.ACP_2445	9.16e-215	680.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YYD3_k127_5577879_14	204669.Acid345_4769	2.5e-38	153.0	COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria,2JK0Q@204432|Acidobacteriia	204432|Acidobacteriia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
YYD3_k127_5577879_11	234267.Acid_6217	4.023e-60	218.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_5577879_10	313606.M23134_02978	1.107e-63	226.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,47PUC@768503|Cytophagia	976|Bacteroidetes	S	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
YYD3_k127_5577879_5	627192.SLG_31280	3.193e-101	337.0	COG4341@1|root,COG4341@2|Bacteria,1RAX5@1224|Proteobacteria,2U5RV@28211|Alphaproteobacteria,2KAD4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5577879_13	215803.DB30_4653	3.105e-53	189.0	COG0662@1|root,COG0662@2|Bacteria,1N1T5@1224|Proteobacteria,42V1T@68525|delta/epsilon subdivisions,2WRU3@28221|Deltaproteobacteria,2YVWP@29|Myxococcales	28221|Deltaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
YYD3_k127_5605536_4	880070.Cycma_2278	1.753e-60	213.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,47JD4@768503|Cytophagia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YYD3_k127_5605536_6	234267.Acid_3837	5.182e-08	66.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_5605536_0	234267.Acid_4577	1.427e-148	488.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
YYD3_k127_5605536_1	94624.Bpet0411	1.845e-113	372.0	COG0600@1|root,COG0600@2|Bacteria,1PC26@1224|Proteobacteria,2VJ97@28216|Betaproteobacteria,3T3G2@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
YYD3_k127_5605536_2	693986.MOC_5042	1.058e-104	346.0	COG1116@1|root,COG1116@2|Bacteria,1MUYG@1224|Proteobacteria,2TVQX@28211|Alphaproteobacteria,1JT6A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
YYD3_k127_5605536_3	94624.Bpet3498	1.45e-94	318.0	COG0715@1|root,COG0715@2|Bacteria,1MWJF@1224|Proteobacteria,2VKCQ@28216|Betaproteobacteria,3T92X@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
YYD3_k127_5610964_1	1123242.JH636435_gene2797	1.922e-105	355.0	COG2010@1|root,COG2010@2|Bacteria,2J547@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5610964_5	1123242.JH636435_gene2796	3.639e-34	139.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_5610964_3	1469607.KK073769_gene5478	5.311e-84	291.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,1G3AR@1117|Cyanobacteria,1HK83@1161|Nostocales	1117|Cyanobacteria	P	C-terminal AAA-associated domain	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
YYD3_k127_5610964_4	1267533.KB906736_gene933	4.867e-36	143.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,3Y2GA@57723|Acidobacteria,2JHTQ@204432|Acidobacteriia	204432|Acidobacteriia	P	ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
YYD3_k127_5610964_6	234267.Acid_7304	5.004e-20	92.0	COG1828@1|root,COG1828@2|Bacteria,3Y5NE@57723|Acidobacteria	57723|Acidobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
YYD3_k127_5610964_2	240015.ACP_0725	1.473e-99	330.0	COG0047@1|root,COG0047@2|Bacteria,3Y2YN@57723|Acidobacteria,2JIBA@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
YYD3_k127_5610964_0	330214.NIDE1392	5.249e-194	617.0	COG0046@1|root,COG0046@2|Bacteria,3J0TJ@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
YYD3_k127_5630714_1	644966.Tmar_0130	1.118e-37	149.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
YYD3_k127_5630714_0	234267.Acid_2177	1.341e-100	365.0	COG4932@1|root,COG4932@2|Bacteria,3Y3KQ@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_5630714_2	518766.Rmar_1603	3.805e-15	79.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1FJCX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
YYD3_k127_5633280_0	446470.Snas_5567	8.716e-38	151.0	COG1266@1|root,COG1266@2|Bacteria,2IAIM@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
YYD3_k127_5633280_2	29581.BW37_03193	1.068e-10	70.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,4726V@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_5633280_1	1459636.NTE_00443	3.034e-20	106.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
YYD3_k127_5651906_0	1254432.SCE1572_47430	7.711e-167	533.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2YU7F@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
YYD3_k127_5651906_1	330214.NIDE1168	1.212e-63	229.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_5651906_4	565033.GACE_1507	1.148e-10	73.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,246SK@183980|Archaeoglobi	183980|Archaeoglobi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_5651906_2	102129.Lepto7375DRAFT_2039	4.443e-21	104.0	COG0589@1|root,COG0589@2|Bacteria,1G895@1117|Cyanobacteria,1HBQ2@1150|Oscillatoriales	1117|Cyanobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_5651906_3	324925.Ppha_2060	4.293e-20	96.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
YYD3_k127_565307_4	682795.AciX8_3483	2.365e-12	68.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
YYD3_k127_565307_1	682795.AciX8_3484	4.026e-66	236.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	204432|Acidobacteriia	Q	pfam abc	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
YYD3_k127_565307_0	1267534.KB906754_gene2972	2.586e-66	244.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
YYD3_k127_565307_2	1340493.JNIF01000004_gene944	8.284e-50	196.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD3_k127_565307_3	309807.SRU_0976	1.27e-17	96.0	COG0729@1|root,COG0729@2|Bacteria,4PF0B@976|Bacteroidetes,1FJXS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
YYD3_k127_5655184_1	243090.RB8505	1.957e-80	284.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_5655184_2	330214.NIDE1525	8.288e-72	244.0	COG0432@1|root,COG0432@2|Bacteria,3J1CB@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
YYD3_k127_5655184_0	671143.DAMO_0098	3.364e-136	462.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_5655184_4	1128421.JAGA01000003_gene3555	1.416e-20	106.0	COG2382@1|root,COG2382@2|Bacteria,2NR4W@2323|unclassified Bacteria	2|Bacteria	P	Putative esterase	fes	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0008150,GO:0008152,GO:0008849,GO:0009056,GO:0009237,GO:0009238,GO:0009712,GO:0009987,GO:0016787,GO:0016788,GO:0018958,GO:0019336,GO:0019439,GO:0019614,GO:0019748,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046214,GO:0046215,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0071704,GO:0090487,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616	-	ko:K07214	-	-	-	-	ko00000	-	-	iECNA114_1301.ECNA114_0527,iSbBS512_1146.SbBS512_E0486	DUF3327,Esterase
YYD3_k127_5655184_6	113355.CM001775_gene2539	3.312e-06	54.0	COG1487@1|root,COG1487@2|Bacteria,1G7H5@1117|Cyanobacteria	1117|Cyanobacteria	K	nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_5655184_5	483219.LILAB_07275	3.436e-14	84.0	2EN73@1|root,33FUY@2|Bacteria,1NHF0@1224|Proteobacteria,43C5M@68525|delta/epsilon subdivisions,2X7FW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
YYD3_k127_5655184_3	1461693.ATO10_00920	3.73e-40	152.0	COG4875@1|root,COG4875@2|Bacteria,1N89Y@1224|Proteobacteria,2UKHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,SnoaL_3
YYD3_k127_5664954_0	234267.Acid_7841	4.654e-167	574.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_5664954_1	204669.Acid345_3552	6.121e-84	300.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K03408,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,CheW,HATPase_c,HisKA,Methyltransf_11,Methyltransf_25,PAS_10,Response_reg
YYD3_k127_5664954_4	269796.Rru_A2429	2.481e-10	61.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,2UGMG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
YYD3_k127_5664954_3	330214.NIDE3842	1.377e-21	98.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
YYD3_k127_5664954_2	575540.Isop_1601	2.425e-77	274.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
YYD3_k127_567029_1	641526.ADIWIN_1231	3.168e-05	53.0	2E5G7@1|root,3307W@2|Bacteria,4P4V4@976|Bacteroidetes,1I9SW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_567029_0	234267.Acid_7841	9.184e-45	178.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_5678222_3	485913.Krac_4174	9.691e-11	72.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5678222_0	1192759.AKIB01000026_gene2163	8.811e-258	815.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales	204457|Sphingomonadales	CG	Dehydrogenase	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_5678222_2	234267.Acid_4616	8.213e-90	305.0	COG2199@1|root,COG3706@2|Bacteria,3Y4ZC@57723|Acidobacteria	57723|Acidobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
YYD3_k127_5678222_1	886293.Sinac_7402	3.431e-167	557.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
YYD3_k127_5678222_4	861299.J421_0904	8.686e-07	56.0	COG1729@1|root,COG3087@1|root,COG1729@2|Bacteria,COG3087@2|Bacteria,1ZTSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_6
YYD3_k127_5679588_2	1267533.KB906741_gene585	1.027e-47	189.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Z9@57723|Acidobacteria,2JKTJ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_5679588_0	675635.Psed_2102	1.455e-100	340.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4DX7E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
YYD3_k127_5679588_1	1123024.AUII01000038_gene4085	8.338e-99	339.0	COG1565@1|root,COG1565@2|Bacteria,2H31V@201174|Actinobacteria	201174|Actinobacteria	S	acr, cog1565	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
YYD3_k127_5679588_3	1267535.KB906767_gene3894	4.8e-08	55.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_5692999_1	177437.HRM2_43560	4.18e-89	306.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria,2MKRM@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
YYD3_k127_5692999_0	330214.NIDE0805	1.897e-136	471.0	COG0784@1|root,COG2198@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YYD3_k127_5692999_2	1454007.JAUG01000024_gene882	3.737e-05	50.0	COG4319@1|root,COG4319@2|Bacteria,4NS0P@976|Bacteroidetes,1IYSY@117747|Sphingobacteriia	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
YYD3_k127_5714293_2	1499689.CCNN01000007_gene2233	2.946e-163	526.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,36H5G@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	sucD	-	1.2.1.76,1.2.1.87	ko:K13922,ko:K18119	ko00640,ko00650,ko01100,ko01200,map00640,map00650,map01100,map01200	-	R09097,R09280	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD3_k127_5714293_0	861299.J421_0813	4.378e-183	585.0	COG0612@1|root,COG0612@2|Bacteria,1ZTAP@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_5714293_1	861299.J421_0812	1.982e-173	560.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
YYD3_k127_5743207_0	1396141.BATP01000060_gene4727	1.474e-204	670.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
YYD3_k127_5743207_4	1304885.AUEY01000032_gene2024	1.836e-15	91.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MJZH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
YYD3_k127_5743207_1	497964.CfE428DRAFT_0066	3.906e-77	284.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
YYD3_k127_5743207_3	1122194.AUHU01000002_gene2690	3.895e-16	93.0	COG0810@1|root,COG3266@1|root,COG3291@1|root,COG0810@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1T46G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	REJ
YYD3_k127_5743207_2	323848.Nmul_A0987	7.086e-48	195.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VWW5@28216|Betaproteobacteria,3741Z@32003|Nitrosomonadales	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
YYD3_k127_5752189_4	1121448.DGI_0189	2.693e-34	131.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2M8J7@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
YYD3_k127_5752189_1	1382359.JIAL01000001_gene2523	5.423e-144	467.0	COG0505@1|root,COG0505@2|Bacteria,3Y31Y@57723|Acidobacteria,2JIB8@204432|Acidobacteriia	204432|Acidobacteriia	F	TIGRFAM Carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
YYD3_k127_5752189_3	204669.Acid345_2191	9.994e-61	215.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria,2JJ4I@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
YYD3_k127_5752189_2	671143.DAMO_1345	1.216e-65	237.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
YYD3_k127_5752189_0	401053.AciPR4_2792	3.079e-199	659.0	COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG1629@2|Bacteria,3Y7DB@57723|Acidobacteria,2JM7W@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_5755457_9	316057.RPD_3573	7.388e-05	50.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,2TRF3@28211|Alphaproteobacteria,3JRDS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Squalene-hopene cyclase C-terminal domain	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
YYD3_k127_5755457_8	247633.GP2143_18131	2.267e-12	73.0	2C42J@1|root,3359Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5755457_6	639030.JHVA01000001_gene1884	5.273e-25	115.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5755457_2	1382359.JIAL01000001_gene1797	2.284e-84	293.0	COG1820@1|root,COG1820@2|Bacteria,3Y3NQ@57723|Acidobacteria,2JIST@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
YYD3_k127_5755457_1	204669.Acid345_2108	1.202e-166	533.0	COG0766@1|root,COG0766@2|Bacteria,3Y2IC@57723|Acidobacteria,2JI7D@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
YYD3_k127_5755457_0	316067.Geob_3570	1.345e-224	710.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42P4F@68525|delta/epsilon subdivisions,2WJVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
YYD3_k127_5755457_4	497964.CfE428DRAFT_5866	2.054e-37	143.0	COG4251@1|root,COG4251@2|Bacteria,46W3X@74201|Verrucomicrobia	74201|Verrucomicrobia	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
YYD3_k127_5755457_5	1123242.JH636434_gene4661	6.149e-30	124.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	kaiB	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	HATPase_c,KaiB,PAS_4,dCache_1
YYD3_k127_5755457_7	326427.Cagg_1364	6.702e-21	108.0	COG3920@1|root,COG3920@2|Bacteria,2GB58@200795|Chloroflexi,377AY@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS
YYD3_k127_5755457_3	497965.Cyan7822_1384	2.118e-56	221.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,3KH7X@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
YYD3_k127_5756728_2	237368.SCABRO_01794	3.105e-92	314.0	COG0031@1|root,COG0031@2|Bacteria,2J2DP@203682|Planctomycetes	203682|Planctomycetes	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
YYD3_k127_5756728_0	1519464.HY22_06855	1.604e-148	482.0	COG0031@1|root,COG0031@2|Bacteria,1FEWW@1090|Chlorobi	1090|Chlorobi	EK	PFAM CBS domain containing protein	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
YYD3_k127_5756728_3	671143.DAMO_2747	6.243e-54	203.0	COG2378@1|root,COG2378@2|Bacteria,2NPY6@2323|unclassified Bacteria	2|Bacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
YYD3_k127_5756728_4	266117.Rxyl_2863	1.969e-33	132.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
YYD3_k127_5759771_3	234267.Acid_2316	1.151e-11	68.0	COG2304@1|root,COG2304@2|Bacteria,3Y6C6@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
YYD3_k127_5759771_1	1340493.JNIF01000003_gene1856	3.484e-157	508.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
YYD3_k127_5759771_0	530564.Psta_1854	3.787e-159	513.0	COG0160@1|root,COG0160@2|Bacteria,2IYBU@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD3_k127_5759771_2	671143.DAMO_3081	2.733e-20	94.0	COG0792@1|root,COG0792@2|Bacteria,2NPW8@2323|unclassified Bacteria	2|Bacteria	L	Nuclease-related domain	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
YYD3_k127_5759771_4	1179226.AJXO01000034_gene1143	0.0002405	44.0	2AWWK@1|root,31NU4@2|Bacteria,1TZQ7@1239|Firmicutes,4II4E@91061|Bacilli,4H142@90964|Staphylococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5780380_3	1144275.COCOR_02369	7.278e-33	136.0	COG0421@1|root,COG0421@2|Bacteria,1QYV9@1224|Proteobacteria	1224|Proteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YYD3_k127_5780380_0	383372.Rcas_2075	1.642e-116	389.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_5780380_2	243090.RB2897	5.744e-56	207.0	COG3963@1|root,COG3963@2|Bacteria,2IZWV@203682|Planctomycetes	203682|Planctomycetes	I	Methyltransferase domain	-	-	2.1.1.344	ko:K22309	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
YYD3_k127_5780380_1	1267535.KB906767_gene224	1.27e-72	252.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria,2JMC0@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_5781155_7	404589.Anae109_3355	3.472e-43	168.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
YYD3_k127_5781155_2	1267535.KB906767_gene1497	9.15e-76	261.0	COG2120@1|root,COG2120@2|Bacteria,3Y3NP@57723|Acidobacteria,2JIEH@204432|Acidobacteriia	204432|Acidobacteriia	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
YYD3_k127_5781155_8	246197.MXAN_3212	3.381e-12	73.0	COG0526@1|root,COG0526@2|Bacteria,1QXUD@1224|Proteobacteria,43C6V@68525|delta/epsilon subdivisions,2X7H3@28221|Deltaproteobacteria,2Z1TN@29|Myxococcales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
YYD3_k127_5781155_4	234267.Acid_1839	9.452e-69	245.0	COG0196@1|root,COG0196@2|Bacteria,3Y34N@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
YYD3_k127_5781155_1	204669.Acid345_2185	9.04e-82	280.0	COG1694@1|root,COG3956@2|Bacteria,3Y46M@57723|Acidobacteria,2JIEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM MazG family protein	-	-	3.6.1.66,3.6.1.9	ko:K02428,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
YYD3_k127_5781155_6	1267534.KB906756_gene499	2.359e-50	186.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_5781155_0	1499680.CCFE01000011_gene752	1.651e-129	425.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus	91061|Bacilli	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
YYD3_k127_5781155_3	379066.GAU_0645	4.877e-73	263.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
YYD3_k127_5781155_5	641149.HMPREF9016_01589	3.526e-64	224.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,2KQV2@206351|Neisseriales	206351|Neisseriales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
YYD3_k127_5781155_10	1396418.BATQ01000051_gene48	3.612e-07	55.0	COG4339@1|root,COG4339@2|Bacteria,46X7F@74201|Verrucomicrobia,2IUV6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5782292_5	204669.Acid345_4558	4.098e-40	160.0	COG3710@1|root,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria,2JMW2@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
YYD3_k127_5782292_8	96561.Dole_1425	5.865e-26	110.0	2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,42VAC@68525|delta/epsilon subdivisions,2WR6Q@28221|Deltaproteobacteria,2MKKP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
YYD3_k127_5782292_3	401053.AciPR4_2749	7.908e-57	205.0	COG0526@1|root,COG0526@2|Bacteria,3Y5H5@57723|Acidobacteria,2JMSM@204432|Acidobacteriia	204432|Acidobacteriia	CO	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
YYD3_k127_5782292_1	234267.Acid_2154	1.857e-96	324.0	COG1409@1|root,COG1409@2|Bacteria,3Y91N@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_5782292_9	1382306.JNIM01000001_gene239	8.614e-22	99.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ysfE	-	2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5	ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234	ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100	M00127	R02530,R03471,R04509,R04734	RC00002,RC00004,RC00017,RC00740,RC01208	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
YYD3_k127_5782292_0	243231.GSU1612	1.635e-113	370.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,42PJM@68525|delta/epsilon subdivisions,2WKJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
YYD3_k127_5782292_4	1128421.JAGA01000003_gene2807	1.165e-47	175.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	-
YYD3_k127_5782292_7	204669.Acid345_2956	3.221e-32	128.0	COG1695@1|root,COG1695@2|Bacteria,3Y5ZR@57723|Acidobacteria,2JK6A@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_5782292_6	1535422.ND16A_1058	1.788e-35	139.0	COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria,1S7BW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_5782292_10	740709.A10D4_08579	5.646e-09	64.0	COG0454@1|root,COG0456@2|Bacteria,1N0SD@1224|Proteobacteria,1S9IW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	SO4716	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_6
YYD3_k127_5782292_2	344747.PM8797T_01814	1.103e-72	278.0	COG1074@1|root,COG1074@2|Bacteria,2IX2I@203682|Planctomycetes	203682|Planctomycetes	L	UvrD REP helicase	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
YYD3_k127_5782292_11	234267.Acid_1905	7.075e-09	68.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
YYD3_k127_5804408_4	319003.Bra1253DRAFT_01103	4.562e-49	178.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2U9EH@28211|Alphaproteobacteria,3JY58@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
YYD3_k127_5804408_5	330214.NIDE1495	5.087e-31	124.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_5804408_7	1125863.JAFN01000001_gene1373	1.196e-05	50.0	2DD8H@1|root,2ZH1Z@2|Bacteria,1PBE0@1224|Proteobacteria,432B3@68525|delta/epsilon subdivisions,2WY4T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5804408_3	886293.Sinac_3784	4.373e-124	402.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_5804408_1	886293.Sinac_3783	2.352e-142	472.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
YYD3_k127_5804408_2	1123389.ATXJ01000001_gene675	7.328e-135	441.0	COG1062@1|root,COG1062@2|Bacteria,1WKA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_5804408_0	1173023.KE650771_gene2934	1.918e-206	654.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
YYD3_k127_5804408_8	266264.Rmet_4892	0.0004264	51.0	COG4654@1|root,COG4654@2|Bacteria,1QV09@1224|Proteobacteria,2WH8U@28216|Betaproteobacteria,1K9JG@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c, class I	-	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3
YYD3_k127_5804408_6	937777.Deipe_2859	3.282e-09	66.0	COG1555@1|root,COG4454@1|root,COG1555@2|Bacteria,COG4454@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Cu_amine_oxidN1,DUF4157,HHH_3,SLBB,SoxE
YYD3_k127_5805035_8	234267.Acid_3123	1.217e-05	53.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
YYD3_k127_5805035_6	1122921.KB898207_gene3327	1.712e-29	131.0	COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,26VD8@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5805035_3	234267.Acid_1337	5.773e-55	203.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
YYD3_k127_5805035_0	1157708.KB907451_gene4569	6.265e-192	613.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VPRQ@28216|Betaproteobacteria,4AJ85@80864|Comamonadaceae	28216|Betaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
YYD3_k127_5805035_2	1267533.KB906741_gene508	1.233e-61	215.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
YYD3_k127_5805035_7	1267535.KB906767_gene2973	1.749e-23	106.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5805035_4	452637.Oter_3715	4.224e-52	197.0	COG3132@1|root,COG3132@2|Bacteria,46VIH@74201|Verrucomicrobia,3K85I@414999|Opitutae	414999|Opitutae	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
YYD3_k127_5805035_1	926566.Terro_3489	2.208e-65	235.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3,DUF1566
YYD3_k127_5805035_5	1380370.JIBA01000003_gene2712	4.179e-35	145.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2GIRE@201174|Actinobacteria,4FGR4@85021|Intrasporangiaceae	201174|Actinobacteria	O	Subtilase family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
YYD3_k127_5810763_5	330214.NIDE4335	3.549e-112	375.0	COG0708@1|root,COG0708@2|Bacteria,3J13K@40117|Nitrospirae	40117|Nitrospirae	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
YYD3_k127_5810763_11	1340493.JNIF01000003_gene2121	1.311e-28	124.0	2CBAE@1|root,32S20@2|Bacteria,3Y93Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5810763_6	1009370.ALO_18390	2.876e-99	338.0	COG1055@1|root,COG1055@2|Bacteria,1TRZC@1239|Firmicutes,4H1XG@909932|Negativicutes	909932|Negativicutes	P	Dicarboxylate carrier MatC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MatC_N
YYD3_k127_5810763_7	1120705.FG95_00566	1.557e-67	243.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,2K4XS@204457|Sphingomonadales	204457|Sphingomonadales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
YYD3_k127_5810763_9	204669.Acid345_2506	2.136e-39	160.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_5810763_8	671143.DAMO_0149	1.112e-66	236.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
YYD3_k127_5810763_3	240292.Ava_4240	7.067e-150	487.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria,1HJSU@1161|Nostocales	1117|Cyanobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
YYD3_k127_5810763_4	627192.SLG_31390	2.286e-135	448.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
YYD3_k127_5810763_0	234267.Acid_5827	4.339e-223	714.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_5810763_1	627192.SLG_31400	5.133e-163	524.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_5810763_2	1267533.KB906735_gene4627	3.877e-159	519.0	COG0539@1|root,COG0539@2|Bacteria,3Y3P3@57723|Acidobacteria,2JI5R@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
YYD3_k127_5810763_10	379066.GAU_0953	2.222e-39	153.0	2BBQ7@1|root,3258A@2|Bacteria,1ZUVG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5811200_1	563192.HMPREF0179_01309	3.294e-78	284.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WMEW@28221|Deltaproteobacteria,2M8IE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
YYD3_k127_5811200_0	1173026.Glo7428_0778	1.345e-128	440.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
YYD3_k127_5822681_7	518766.Rmar_0105	1.495e-31	126.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1FINU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YYD3_k127_5822681_4	323098.Nwi_2419	9.346e-71	246.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3JR83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD3_k127_5822681_5	1313301.AUGC01000003_gene2029	6.337e-69	239.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
YYD3_k127_5822681_6	1121406.JAEX01000002_gene965	5.205e-46	175.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2M8NI@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
YYD3_k127_5822681_3	404589.Anae109_3561	3.937e-87	304.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YUQI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_5822681_1	1297742.A176_03598	1.886e-127	415.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42PK8@68525|delta/epsilon subdivisions,2X5GR@28221|Deltaproteobacteria,2YV7E@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
YYD3_k127_5822681_0	370438.PTH_0777	1.203e-143	461.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,2611J@186807|Peptococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
YYD3_k127_5822681_2	370438.PTH_0776	3.754e-108	361.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,261NQ@186807|Peptococcaceae	186801|Clostridia	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
YYD3_k127_5857479_1	1173025.GEI7407_2215	1.341e-110	370.0	COG1653@1|root,COG1653@2|Bacteria,1G0AA@1117|Cyanobacteria,1H7SU@1150|Oscillatoriales	1117|Cyanobacteria	G	Carbohydrate ABC transporter substrate-binding protein, CUT1 family	ugpB	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
YYD3_k127_5857479_2	368408.Tpen_1547	1.673e-96	327.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
YYD3_k127_5857479_3	883126.HMPREF9710_00176	2.045e-44	166.0	292BS@1|root,2ZPW7@2|Bacteria,1REGA@1224|Proteobacteria,2VTQU@28216|Betaproteobacteria,474IK@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5857479_5	234267.Acid_3837	8.25e-08	66.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
YYD3_k127_5857479_0	234267.Acid_4580	1.408e-119	404.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	dap	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,DAP_B
YYD3_k127_5857479_4	1235797.C816_02590	3.137e-11	71.0	2E3HW@1|root,32YGE@2|Bacteria,1VQA5@1239|Firmicutes,2542K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5863258_2	448385.sce2666	5.601e-13	75.0	COG3861@1|root,COG3861@2|Bacteria,1QE0P@1224|Proteobacteria,42TDZ@68525|delta/epsilon subdivisions,2WPW5@28221|Deltaproteobacteria,2Z2TG@29|Myxococcales	28221|Deltaproteobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5863258_1	1304885.AUEY01000012_gene1826	8.32e-17	83.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
YYD3_k127_5871029_0	1173027.Mic7113_3984	5.705e-131	441.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HA21@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
YYD3_k127_5871029_1	344747.PM8797T_06150	1.498e-107	367.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5871029_3	1463936.JOJI01000060_gene5945	8.934e-84	297.0	COG0793@1|root,COG0793@2|Bacteria,2GN4H@201174|Actinobacteria	201174|Actinobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
YYD3_k127_5871029_5	204669.Acid345_2334	1.382e-36	148.0	COG2948@1|root,COG2948@2|Bacteria,3Y81Q@57723|Acidobacteria,2JN9S@204432|Acidobacteriia	204432|Acidobacteriia	U	multi-organism process	-	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
YYD3_k127_5871029_4	118161.KB235922_gene2761	3.172e-42	162.0	COG0127@1|root,COG0127@2|Bacteria,1G033@1117|Cyanobacteria,3VHMA@52604|Pleurocapsales	1117|Cyanobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
YYD3_k127_5871029_2	1094508.Tsac_2551	3.343e-90	303.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,42F6J@68295|Thermoanaerobacterales	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
YYD3_k127_5871029_6	1047013.AQSP01000139_gene2399	3.402e-19	98.0	COG5401@1|root,COG5401@2|Bacteria,2NPV5@2323|unclassified Bacteria	2|Bacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
YYD3_k127_5871029_7	189425.PGRAT_20570	2.064e-05	51.0	COG0860@1|root,COG0860@2|Bacteria,1V5SF@1239|Firmicutes,4HJNA@91061|Bacilli,26RP7@186822|Paenibacillaceae	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
YYD3_k127_5875706_1	639030.JHVA01000001_gene1233	2.65e-51	200.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
YYD3_k127_5875706_2	1267535.KB906767_gene4945	1.89e-38	147.0	COG0251@1|root,COG0251@2|Bacteria,3Y5DN@57723|Acidobacteria,2JN2R@204432|Acidobacteriia	204432|Acidobacteriia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YYD3_k127_5875706_0	204669.Acid345_0175	2.636e-281	882.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
YYD3_k127_5875706_3	1304872.JAGC01000005_gene1959	6.938e-35	136.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Q0C@68525|delta/epsilon subdivisions,2WIIZ@28221|Deltaproteobacteria,2MDPJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
YYD3_k127_5875841_5	179408.Osc7112_3264	5.763e-27	117.0	COG4636@1|root,COG4636@2|Bacteria,1G55I@1117|Cyanobacteria,1HATI@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
YYD3_k127_5875841_7	314231.FP2506_18669	1.31e-12	71.0	2E9WT@1|root,3342I@2|Bacteria,1NBEH@1224|Proteobacteria,2UFGC@28211|Alphaproteobacteria,2PM4Q@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	MA20_00895	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
YYD3_k127_5875841_1	506534.Rhein_2117	8.316e-59	206.0	COG4898@1|root,COG4898@2|Bacteria,1N0Z1@1224|Proteobacteria,1SQ7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5875841_3	402777.KB235904_gene4216	4.751e-38	149.0	COG1670@1|root,COG1670@2|Bacteria,1G5MS@1117|Cyanobacteria,1HASJ@1150|Oscillatoriales	1117|Cyanobacteria	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YYD3_k127_5875841_0	330084.JNYZ01000001_gene3228	2.988e-137	455.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4E95H@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3,NAD_binding_8
YYD3_k127_5875841_6	1101188.KI912155_gene3004	8.928e-21	102.0	2DB8V@1|root,2Z7SX@2|Bacteria,2IA72@201174|Actinobacteria	201174|Actinobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
YYD3_k127_5875841_2	715451.ambt_12010	6.075e-54	207.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5875841_4	1128421.JAGA01000003_gene3264	9.44e-30	127.0	COG1404@1|root,COG1404@2|Bacteria,2NQU8@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8
YYD3_k127_5888609_8	313628.LNTAR_09736	8.284e-07	57.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Abhydrolase_8,DLH,Esterase,Peptidase_S9
YYD3_k127_5888609_1	398578.Daci_4386	3.431e-199	629.0	COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2VIVN@28216|Betaproteobacteria,4AC5F@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM monooxygenase FAD-binding	-	-	1.14.13.218	ko:K20940	ko00405,ko01130,map00405,map01130	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
YYD3_k127_5888609_5	491952.Mar181_2202	6.604e-30	121.0	2E3DE@1|root,32YCK@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
YYD3_k127_5888609_3	221288.JH992901_gene4291	1.269e-125	413.0	COG0436@1|root,COG0436@2|Bacteria,1G202@1117|Cyanobacteria,1JKEM@1189|Stigonemataceae	1117|Cyanobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_5888609_4	376686.Fjoh_3878	1.772e-112	372.0	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,1HWW6@117743|Flavobacteriia,2NV2G@237|Flavobacterium	976|Bacteroidetes	P	esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SASA
YYD3_k127_5888609_0	234267.Acid_0260	1.427e-223	710.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Tannase
YYD3_k127_5888609_2	1458357.BG58_15405	1.58e-148	481.0	COG0477@1|root,COG2814@2|Bacteria,1NGB4@1224|Proteobacteria,2WEBU@28216|Betaproteobacteria,1K022@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YYD3_k127_5888609_7	639030.JHVA01000001_gene1885	9.369e-12	70.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5888609_6	195250.CM001776_gene1121	9.139e-28	119.0	COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria,1H175@1129|Synechococcus	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5892118_5	459349.CLOAM1714	4.684e-08	57.0	COG0281@1|root,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	mez_1	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
YYD3_k127_5892118_2	2340.JV46_19800	1.192e-85	292.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,1RRQ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Helix-hairpin-helix domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_5,HHH_8
YYD3_k127_5892118_4	1144275.COCOR_01204	4.215e-17	87.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,Hemerythrin,NnrS
YYD3_k127_5892118_0	240292.Ava_4115	1.219e-127	418.0	COG0334@1|root,COG0334@2|Bacteria,1G4HR@1117|Cyanobacteria,1HRGB@1161|Nostocales	1117|Cyanobacteria	C	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
YYD3_k127_5892118_3	1158165.KB898877_gene1190	3.701e-61	217.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
YYD3_k127_5892118_6	502558.EGYY_28160	0.0001531	49.0	COG4980@1|root,COG4980@2|Bacteria,2HTT2@201174|Actinobacteria,4CW82@84998|Coriobacteriia	84998|Coriobacteriia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
YYD3_k127_5892118_1	404589.Anae109_0600	2.293e-100	338.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria	1224|Proteobacteria	K	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD
YYD3_k127_5918528_3	234267.Acid_4171	5.041e-28	130.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_5918528_1	204669.Acid345_2969	3.063e-266	844.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
YYD3_k127_5918528_2	530564.Psta_0198	5.08e-72	253.0	COG0583@1|root,COG0583@2|Bacteria,2IYFV@203682|Planctomycetes	203682|Planctomycetes	K	COG0583 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD3_k127_5918528_0	671143.DAMO_0867	0.0	1755.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
YYD3_k127_5921943_1	76114.ebA3092	4.536e-29	123.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,2KZN0@206389|Rhodocyclales	206389|Rhodocyclales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
YYD3_k127_5921943_0	378806.STAUR_6894	1.661e-72	259.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria	1224|Proteobacteria	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
YYD3_k127_5930776_0	234267.Acid_7087	3.722e-133	441.0	COG1680@1|root,COG1680@2|Bacteria,3Y6F4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	3.4.16.4	ko:K18988	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase,DUF3471
YYD3_k127_5930776_1	641526.ADIWIN_0756	8.769e-34	139.0	COG5395@1|root,COG5395@2|Bacteria,4NSVW@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
YYD3_k127_5930776_2	1444310.JANV01000048_gene2149	8.171e-08	64.0	2BRCM@1|root,32KBA@2|Bacteria,1TVE3@1239|Firmicutes,4I9K6@91061|Bacilli,1ZJY4@1386|Bacillus	91061|Bacilli	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
YYD3_k127_5935634_2	1382359.JIAL01000001_gene2258	1.793e-53	191.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria,2JIDE@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
YYD3_k127_5935634_1	330214.NIDE1061	1.197e-55	200.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
YYD3_k127_5935634_0	1297742.A176_07148	0.0	1180.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
YYD3_k127_5935634_3	439235.Dalk_3449	2.53e-24	108.0	2954S@1|root,2ZSHC@2|Bacteria	2|Bacteria	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
YYD3_k127_5951074_1	1379270.AUXF01000007_gene993	1.484e-40	155.0	COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,FlgD_ig,NHL
YYD3_k127_5951074_2	926560.KE387023_gene2058	3.275e-23	102.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
YYD3_k127_5951074_0	1267534.KB906754_gene3507	4.794e-247	792.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
YYD3_k127_5951074_3	761193.Runsl_1555	1.441e-05	56.0	2ADWP@1|root,313NS@2|Bacteria,4NN12@976|Bacteroidetes,47PBM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5954343_5	555793.WSK_1942	4.34e-15	87.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5954343_4	555793.WSK_3225	1.904e-15	81.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5954343_7	483219.LILAB_34325	2.704e-07	62.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14,4.2.2.2	ko:K01183,ko:K01728	ko00040,ko00520,ko01100,ko02024,map00040,map00520,map01100,map02024	-	R01206,R02334,R02361,R06240	RC00049,RC00467,RC00705	ko00000,ko00001,ko01000	-	GH18	-	An_peroxidase,Big_5,ChiC,F5_F8_type_C,Flg_new,Glyco_hydro_18,Glyco_hydro_92,Pec_lyase_C,SLH,fn3
YYD3_k127_5954343_3	627192.SLG_09880	3.847e-19	98.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5954343_6	113395.AXAI01000010_gene2219	1.152e-14	81.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,3K43P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5954343_0	1267533.KB906736_gene1246	3.427e-40	169.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_5954343_2	344747.PM8797T_13947	1.138e-22	113.0	COG1520@1|root,COG1572@1|root,COG2373@1|root,COG2931@1|root,COG3203@1|root,COG3266@1|root,COG3391@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3203@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
YYD3_k127_5954343_1	1192759.AKIB01000028_gene2028	7.547e-36	154.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3386@1|root,COG3391@1|root,COG5276@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2UHRC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FGMQ	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,He_PIG,Laminin_G_3
YYD3_k127_5954380_0	1000565.METUNv1_02392	6.081e-224	710.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KYIX@206389|Rhodocyclales	206389|Rhodocyclales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
YYD3_k127_5954380_1	1232410.KI421428_gene1003	2.669e-64	235.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
YYD3_k127_596271_3	243231.GSU1767	1.904e-98	329.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43TW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YYD3_k127_596271_1	945713.IALB_0026	1.864e-173	549.0	COG1830@1|root,COG1830@2|Bacteria	2|Bacteria	G	lyase activity	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
YYD3_k127_596271_6	123214.PERMA_1409	9.904e-17	81.0	2DNS1@1|root,32YVX@2|Bacteria,2G4CS@200783|Aquificae	200783|Aquificae	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
YYD3_k127_596271_5	278963.ATWD01000001_gene1601	2.297e-52	192.0	COG0105@1|root,COG0105@2|Bacteria,3Y4MW@57723|Acidobacteria,2JJD4@204432|Acidobacteriia	204432|Acidobacteriia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
YYD3_k127_596271_2	234267.Acid_3377	3.482e-135	435.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria	57723|Acidobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
YYD3_k127_596271_0	1267535.KB906767_gene3553	3.492e-174	553.0	COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
YYD3_k127_596271_8	861299.J421_6007	1.68e-05	51.0	2DCBP@1|root,2ZDJZ@2|Bacteria,1ZU6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
YYD3_k127_596271_4	379066.GAU_2821	2.811e-70	254.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_596271_7	330214.NIDE0577	5.583e-08	59.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
YYD3_k127_596458_5	661478.OP10G_1299	5.019e-31	126.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
YYD3_k127_596458_0	309801.trd_A0592	3.599e-143	469.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,27Y3Q@189775|Thermomicrobia	189775|Thermomicrobia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YYD3_k127_596458_3	1379270.AUXF01000003_gene3619	8.339e-58	224.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_596458_1	1340493.JNIF01000003_gene1475	3.32e-91	321.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_596458_2	1340493.JNIF01000003_gene3474	3.31e-74	257.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
YYD3_k127_5966847_6	1089553.Tph_c25480	5.535e-46	171.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,42F2M@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YYD3_k127_5966847_9	401053.AciPR4_2053	3.806e-32	134.0	COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria,2JIE8@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
YYD3_k127_5966847_11	1173024.KI912149_gene6250	1.364e-22	102.0	2DNMG@1|root,32Y46@2|Bacteria,1GI2P@1117|Cyanobacteria,1JM3Q@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5966847_1	493475.GARC_5183	7.359e-120	399.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
YYD3_k127_5966847_0	1267535.KB906767_gene4529	2.226e-160	514.0	COG0137@1|root,COG0137@2|Bacteria,3Y4Y9@57723|Acidobacteria,2JJKA@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YYD3_k127_5966847_2	211586.SO_0277	2.32e-76	267.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,2Q9YD@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
YYD3_k127_5966847_10	204669.Acid345_4162	2.368e-24	107.0	COG1438@1|root,COG1438@2|Bacteria,3Y551@57723|Acidobacteria,2JJTA@204432|Acidobacteriia	204432|Acidobacteriia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
YYD3_k127_5966847_7	1124780.ANNU01000020_gene3260	2.838e-37	146.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
YYD3_k127_5966847_4	357808.RoseRS_4097	3.673e-65	228.0	COG1898@1|root,COG1898@2|Bacteria,2GAEU@200795|Chloroflexi,375UW@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
YYD3_k127_5966847_3	204669.Acid345_0557	3.342e-70	250.0	COG1559@1|root,COG1559@2|Bacteria,3Y2RD@57723|Acidobacteria,2JIQ0@204432|Acidobacteriia	204432|Acidobacteriia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
YYD3_k127_5966847_8	1487921.DP68_05995	7.491e-36	140.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,36IV4@31979|Clostridiaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
YYD3_k127_5966847_5	1267535.KB906767_gene4586	1.894e-61	225.0	COG0793@1|root,COG0793@2|Bacteria,3Y3A7@57723|Acidobacteria,2JHJK@204432|Acidobacteriia	204432|Acidobacteriia	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
YYD3_k127_5973186_0	234267.Acid_5827	7.051e-130	426.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
YYD3_k127_5973186_1	627192.SLG_31400	4.367e-109	368.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_5973186_3	1379270.AUXF01000003_gene3619	1.654e-43	177.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5973186_2	1206101.AZXC01000011_gene1692	6.55e-93	310.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
YYD3_k127_5973186_4	641143.HMPREF9331_02375	0.0006611	48.0	COG0501@1|root,COG0501@2|Bacteria,4PCIJ@976|Bacteroidetes,1IFS5@117743|Flavobacteriia,1ER5S@1016|Capnocytophaga	976|Bacteroidetes	O	Peptidase M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
YYD3_k127_5987122_1	246197.MXAN_4235	9.219e-288	893.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
YYD3_k127_5987122_9	1382359.JIAL01000001_gene1861	1.297e-34	136.0	COG0316@1|root,COG0316@2|Bacteria,3Y4ZB@57723|Acidobacteria,2JJEX@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
YYD3_k127_5987122_11	204669.Acid345_1805	2.577e-24	109.0	COG2151@1|root,COG2151@2|Bacteria,3Y5G8@57723|Acidobacteria,2JP2G@204432|Acidobacteriia	204432|Acidobacteriia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
YYD3_k127_5987122_0	1267535.KB906767_gene4766	1.316e-295	922.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
YYD3_k127_5987122_12	1123229.AUBC01000012_gene2713	5.249e-12	72.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,3JWAZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
YYD3_k127_5987122_10	330214.NIDE0974	8.709e-27	118.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
YYD3_k127_5987122_3	1341151.ASZU01000026_gene1120	1.392e-128	417.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,27BEG@186824|Thermoactinomycetaceae	91061|Bacilli	O	Pyridine nucleotide-disulphide oxidoreductase	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
YYD3_k127_5987122_13	1415778.JQMM01000001_gene2084	3.046e-05	49.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5987122_7	1121920.AUAU01000009_gene1864	1.763e-38	160.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_5987122_4	1157490.EL26_23240	1.31e-98	332.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4HEB4@91061|Bacilli,27950@186823|Alicyclobacillaceae	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_5987122_6	1122919.KB905549_gene2131	2.675e-46	177.0	COG4587@1|root,COG4587@2|Bacteria,1UZ3Y@1239|Firmicutes,4HFHM@91061|Bacilli,26V8Z@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
YYD3_k127_5987122_5	292459.STH1199	7.372e-68	239.0	COG3694@1|root,COG3694@2|Bacteria,1V1MN@1239|Firmicutes,24EE6@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
YYD3_k127_5987122_8	234267.Acid_1401	3.83e-36	144.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
YYD3_k127_5987122_2	1254432.SCE1572_05425	2.64e-156	506.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QV3@68525|delta/epsilon subdivisions,2WMT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
YYD3_k127_6003748_5	886293.Sinac_7498	2.137e-19	94.0	COG2010@1|root,COG2010@2|Bacteria,2IXZ4@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
YYD3_k127_6003748_0	398767.Glov_2643	3.817e-259	811.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
YYD3_k127_6003748_2	1231391.AMZF01000039_gene547	1e-116	394.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2W8GX@28216|Betaproteobacteria,3T709@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
YYD3_k127_6003748_1	1340493.JNIF01000003_gene2427	1.089e-123	414.0	COG3182@1|root,COG3182@2|Bacteria	2|Bacteria	E	Iron-regulated membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
YYD3_k127_6003748_4	1123020.AUIE01000005_gene4259	8.896e-71	252.0	COG2267@1|root,COG2267@2|Bacteria,1N9CI@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
YYD3_k127_6003748_3	1082933.MEA186_23196	1.362e-104	353.0	COG2141@1|root,COG2141@2|Bacteria,1MUTJ@1224|Proteobacteria,2TTZI@28211|Alphaproteobacteria,43I7M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
YYD3_k127_6033637_1	264731.PRU_1563	1.432e-121	402.0	COG0463@1|root,COG2385@1|root,COG4468@1|root,COG0463@2|Bacteria,COG2385@2|Bacteria,COG4468@2|Bacteria,4NG21@976|Bacteroidetes,2FP4W@200643|Bacteroidia	976|Bacteroidetes	D	SpoIID LytB domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
YYD3_k127_6033637_2	385682.AFSL01000008_gene2630	1.843e-54	207.0	COG4360@1|root,COG4360@2|Bacteria,4NHAH@976|Bacteroidetes,2FMAC@200643|Bacteroidia,3XJT1@558415|Marinilabiliaceae	976|Bacteroidetes	F	Domain of unknown function (DUF4922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4922
YYD3_k127_6033637_0	762982.HMPREF9442_01759	1.869e-140	456.0	COG0463@1|root,COG2385@1|root,COG4360@1|root,COG0463@2|Bacteria,COG2385@2|Bacteria,COG4360@2|Bacteria,4NEQ9@976|Bacteroidetes,2G2IE@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4922,Glycos_transf_2,SpoIID
YYD3_k127_6036350_3	1089553.Tph_c14380	2.812e-64	229.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,42F7U@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
YYD3_k127_6036350_2	1294265.JCM21738_85	1.162e-92	317.0	COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,1ZCBR@1386|Bacillus	91061|Bacilli	O	COG0492 Thioredoxin reductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
YYD3_k127_6036350_4	671143.DAMO_2918	1.363e-21	100.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_7
YYD3_k127_6036350_1	335543.Sfum_0113	5.969e-124	405.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2MQFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YYD3_k127_6036350_0	234267.Acid_5782	0.0	1077.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
YYD3_k127_6044047_3	1198452.Jab_1c07070	1.676e-59	212.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,4742C@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
YYD3_k127_6044047_2	1317122.ATO12_23175	1.198e-71	251.0	COG0500@1|root,COG2226@2|Bacteria,4PH0U@976|Bacteroidetes,1IHRF@117743|Flavobacteriia,2YIT4@290174|Aquimarina	976|Bacteroidetes	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_6044047_1	264198.Reut_B5103	1.205e-84	286.0	COG3145@1|root,COG3145@2|Bacteria,1N5HB@1224|Proteobacteria,2VHNU@28216|Betaproteobacteria,1K2E9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Alkylated DNA repair protein	alkB	-	1.14.11.33	ko:K03919	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	2OG-FeII_Oxy_2
YYD3_k127_6044047_0	204669.Acid345_4586	1.381e-290	898.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria,2JI2P@204432|Acidobacteriia	57723|Acidobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
YYD3_k127_6048024_5	204669.Acid345_1561	2.184e-82	289.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia	204432|Acidobacteriia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
YYD3_k127_6048024_4	240015.ACP_3433	1.012e-90	302.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia	204432|Acidobacteriia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
YYD3_k127_6048024_3	644966.Tmar_2225	9.408e-168	536.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WCCB@538999|Clostridiales incertae sedis	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
YYD3_k127_6048024_0	56780.SYN_02787	1.051e-278	878.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_6048024_6	1122918.KB907259_gene833	9.15e-55	198.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
YYD3_k127_6048024_1	1267535.KB906767_gene3177	6.721e-235	732.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
YYD3_k127_6048024_2	234267.Acid_0368	8.91e-179	569.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YYD3_k127_6049680_8	639030.JHVA01000001_gene1982	1.964e-09	62.0	COG1629@1|root,COG4771@2|Bacteria,3Y3A5@57723|Acidobacteria,2JNZT@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6049680_3	234267.Acid_1441	8.885e-55	209.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
YYD3_k127_6049680_4	234267.Acid_1440	1.269e-41	164.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
YYD3_k127_6049680_1	658187.LDG_6881	1.912e-74	267.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1JFGY@118969|Legionellales	118969|Legionellales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_6049680_2	551789.ATVJ01000001_gene1038	1.733e-57	216.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6049680_5	216591.BCAM2081	6.554e-29	121.0	COG2867@1|root,COG2867@2|Bacteria,1N9F0@1224|Proteobacteria,2VWY4@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
YYD3_k127_6049680_6	627192.SLG_25140	5.123e-28	126.0	2EVK9@1|root,33P0C@2|Bacteria,1NDYB@1224|Proteobacteria,2UQHZ@28211|Alphaproteobacteria,2K9N4@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6049680_0	935840.JAEQ01000003_gene279	1.31e-184	583.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	2.1.1.341	ko:K15066	ko00627,ko01120,map00627,map01120	-	R09271,R10136	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
YYD3_k127_6068241_5	1198114.AciX9_0382	5.179e-10	67.0	COG2989@1|root,COG2989@2|Bacteria,3Y2YW@57723|Acidobacteria,2JIFK@204432|Acidobacteriia	204432|Acidobacteriia	S	ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
YYD3_k127_6068241_2	1183438.GKIL_0293	3.617e-33	136.0	COG2802@1|root,COG2802@2|Bacteria,1G0PB@1117|Cyanobacteria	1117|Cyanobacteria	S	to the N-terminal domain of Lon protease'	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
YYD3_k127_6068241_4	204669.Acid345_2264	4.1e-16	83.0	COG4980@1|root,COG4980@2|Bacteria,3Y5IA@57723|Acidobacteria,2JK01@204432|Acidobacteriia	204432|Acidobacteriia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
YYD3_k127_6068241_0	204669.Acid345_3117	6.181e-212	674.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
YYD3_k127_6068241_1	1041930.Mtc_0650	1.431e-66	235.0	COG2094@1|root,arCOG04295@2157|Archaea,2Y0AE@28890|Euryarchaeota,2NB07@224756|Methanomicrobia	224756|Methanomicrobia	L	alkylbase DNA N-glycosylase activity	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
YYD3_k127_6077595_5	1411123.JQNH01000001_gene1790	1.883e-28	117.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TRBG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
YYD3_k127_6077595_4	867903.ThesuDRAFT_02150	6.721e-38	151.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YYD3_k127_6077595_2	867903.ThesuDRAFT_02149	1.894e-75	258.0	COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,24SBR@186801|Clostridia	186801|Clostridia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
YYD3_k127_6077595_8	743525.TSC_c00960	0.0002876	48.0	COG5605@1|root,COG5605@2|Bacteria,1WKGR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
YYD3_k127_6077595_7	1046627.BZARG_1953	6.319e-11	66.0	2E3I4@1|root,32YGK@2|Bacteria,4NUQ9@976|Bacteroidetes,1I53J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6077595_1	344747.PM8797T_11831	1.071e-133	437.0	COG0673@1|root,COG0673@2|Bacteria,2IZC8@203682|Planctomycetes	203682|Planctomycetes	C	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_6077595_3	1267535.KB906767_gene3861	4.23e-47	176.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
YYD3_k127_6077595_0	234267.Acid_3236	1.73e-163	532.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_6105612_5	248742.XP_005648693.1	1.974e-14	79.0	COG0564@1|root,KOG1919@2759|Eukaryota,37QPT@33090|Viridiplantae,34INK@3041|Chlorophyta	3041|Chlorophyta	A	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
YYD3_k127_6105612_4	1382356.JQMP01000001_gene1258	1.365e-21	103.0	COG1802@1|root,COG1802@2|Bacteria,2G97X@200795|Chloroflexi,27YN7@189775|Thermomicrobia	189775|Thermomicrobia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
YYD3_k127_6105612_0	1123229.AUBC01000005_gene716	9.799e-158	507.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria,3JSNQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
YYD3_k127_6105612_1	682795.AciX8_3558	4.228e-138	454.0	COG1506@1|root,COG1506@2|Bacteria,3Y6MJ@57723|Acidobacteria,2JMBK@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_6105612_2	324602.Caur_0773	7.484e-86	296.0	COG0596@1|root,COG0596@2|Bacteria,2G8HQ@200795|Chloroflexi,376XF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
YYD3_k127_6105612_3	670307.HYPDE_34408	2.036e-49	192.0	COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,2TUS4@28211|Alphaproteobacteria,3N7RX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
YYD3_k127_6109437_2	379066.GAU_2318	6.465e-05	48.0	COG1629@1|root,COG4771@2|Bacteria,1ZUBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
YYD3_k127_6109437_1	1267535.KB906767_gene566	1.695e-118	385.0	COG0745@1|root,COG0745@2|Bacteria,3Y38C@57723|Acidobacteria,2JIPX@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
YYD3_k127_6109437_0	1340493.JNIF01000004_gene603	8.529e-147	475.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7
YYD3_k127_6111011_2	234267.Acid_4772	8.758e-30	121.0	COG1695@1|root,COG1695@2|Bacteria,3Y7WH@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_6111011_0	861299.J421_0949	8.365e-211	686.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0949|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6111011_3	880073.Calab_2048	8.068e-05	48.0	2DR6U@1|root,33AFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6111011_1	1122970.AUHC01000021_gene2458	2.818e-39	153.0	COG3794@1|root,COG3794@2|Bacteria,1R29B@1224|Proteobacteria	1224|Proteobacteria	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
YYD3_k127_6140323_2	1410670.JHXF01000017_gene1919	4.45e-19	100.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,248HG@186801|Clostridia,3WHJT@541000|Ruminococcaceae	186801|Clostridia	M	PFAM Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
YYD3_k127_6140323_1	1237500.ANBA01000035_gene583	1.874e-35	144.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4EIYP@85012|Streptosporangiales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
YYD3_k127_6140323_0	234267.Acid_7098	2.208e-64	226.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
YYD3_k127_6140323_3	1231241.Mc24_03633	1.103e-15	79.0	COG1254@1|root,COG1254@2|Bacteria,2GDJK@200918|Thermotogae	200918|Thermotogae	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YYD3_k127_6145160_0	234267.Acid_0738	1.216e-69	262.0	COG5316@1|root,COG5316@2|Bacteria,3Y46P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
YYD3_k127_6145160_3	269799.Gmet_3542	8.195e-05	55.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,43URZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
YYD3_k127_6145160_1	1037409.BJ6T_19240	3.24e-45	170.0	2DM5T@1|root,31U0Y@2|Bacteria,1RJ9U@1224|Proteobacteria,2UA0D@28211|Alphaproteobacteria,3JZFV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
YYD3_k127_6155853_6	1125863.JAFN01000001_gene1090	1.427e-100	343.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
YYD3_k127_6155853_0	344747.PM8797T_10564	1.104e-175	555.0	COG1063@1|root,COG1063@2|Bacteria,2IX2U@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
YYD3_k127_6155853_2	103733.JNYO01000004_gene7495	2.539e-170	542.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4DXR1@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
YYD3_k127_6155853_3	1144275.COCOR_02903	1.482e-150	485.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,42SM7@68525|delta/epsilon subdivisions,2WP5E@28221|Deltaproteobacteria,2YYGZ@29|Myxococcales	28221|Deltaproteobacteria	G	Converts alpha-aldose to the beta-anomer	galM2	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
YYD3_k127_6155853_7	1123242.JH636434_gene5244	4.784e-82	296.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6155853_8	644282.Deba_1555	0.0007516	52.0	COG2204@1|root,COG2204@2|Bacteria,1NTM2@1224|Proteobacteria,42ZAS@68525|delta/epsilon subdivisions,2WUBV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
YYD3_k127_6155853_4	234267.Acid_5375	2.317e-123	410.0	COG2010@1|root,COG2010@2|Bacteria,3Y44D@57723|Acidobacteria	57723|Acidobacteria	C	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6155853_1	1267534.KB906756_gene343	5.937e-173	562.0	COG0412@1|root,COG0412@2|Bacteria,3Y2PZ@57723|Acidobacteria,2JKJA@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6155853_5	1267535.KB906767_gene2307	2.527e-111	385.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	asmA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
YYD3_k127_6163000_4	666685.R2APBS1_3742	5.004e-20	92.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6163000_1	450851.PHZ_c3106	6.092e-129	423.0	COG1960@1|root,COG1960@2|Bacteria,1MW97@1224|Proteobacteria,2TUS1@28211|Alphaproteobacteria,2KHM1@204458|Caulobacterales	204458|Caulobacterales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
YYD3_k127_6163000_0	314230.DSM3645_17370	3.079e-201	642.0	COG0008@1|root,COG0008@2|Bacteria,2IXD6@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
YYD3_k127_6163000_3	234267.Acid_3566	4.341e-88	298.0	COG3823@1|root,COG3823@2|Bacteria,3Y4G6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
YYD3_k127_6163000_2	264732.Moth_1867	1e-102	343.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42F1S@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
YYD3_k127_6180057_3	401053.AciPR4_2577	2.82e-22	98.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_6180057_4	926566.Terro_1783	2.469e-12	73.0	COG0627@1|root,COG0627@2|Bacteria,3Y63W@57723|Acidobacteria,2JMD1@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_6180057_5	1288963.ADIS_0792	1.939e-10	67.0	COG0627@1|root,COG1506@1|root,COG0627@2|Bacteria,COG1506@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_6180057_1	1122604.JONR01000045_gene2509	9.342e-85	284.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1X6NC@135614|Xanthomonadales	135614|Xanthomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
YYD3_k127_6180057_2	1340493.JNIF01000003_gene4300	4.805e-62	235.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y45M@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,SpoIIE
YYD3_k127_6180057_0	644282.Deba_1067	3.514e-97	339.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
YYD3_k127_6180063_1	1121918.ARWE01000001_gene2619	3.253e-43	174.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH,Paired_CXXCH_1
YYD3_k127_6180063_4	1095769.CAHF01000010_gene1115	1.305e-30	130.0	COG5637@1|root,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,2WGS9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,Polyketide_cyc
YYD3_k127_6180063_2	404589.Anae109_3323	2.443e-38	150.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WNF6@28221|Deltaproteobacteria,2Z15B@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
YYD3_k127_6180063_5	1267534.KB906754_gene2607	1.601e-13	78.0	COG0586@1|root,COG0586@2|Bacteria,3Y4JN@57723|Acidobacteria,2JJ9B@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YYD3_k127_6180063_3	234267.Acid_3425	1.884e-36	157.0	COG4932@1|root,COG4932@2|Bacteria,3Y7YN@57723|Acidobacteria	57723|Acidobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6180063_0	1037409.BJ6T_34810	6.5e-110	374.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3JSFY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	MA20_34345	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
YYD3_k127_6199522_1	1173026.Glo7428_3072	4.065e-92	311.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G0P4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
YYD3_k127_6199522_0	1267535.KB906767_gene1503	3.24e-97	329.0	COG4301@1|root,COG4301@2|Bacteria,3Y2JF@57723|Acidobacteria,2JIA5@204432|Acidobacteriia	204432|Acidobacteriia	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
YYD3_k127_6199522_2	234267.Acid_1271	9.781e-64	225.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_6203315_11	1267535.KB906767_gene3608	8.746e-12	65.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria,2JHPV@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
YYD3_k127_6203315_9	794903.OPIT5_25680	1.958e-17	88.0	COG1131@1|root,COG1131@2|Bacteria,46V0T@74201|Verrucomicrobia,3K9MC@414999|Opitutae	414999|Opitutae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_6203315_5	756272.Plabr_0440	1.905e-34	152.0	2DW2Z@1|root,32V0P@2|Bacteria,2J0A0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6203315_1	756272.Plabr_0439	1.035e-120	396.0	COG0714@1|root,COG0714@2|Bacteria,2IXCY@203682|Planctomycetes	203682|Planctomycetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
YYD3_k127_6203315_6	756272.Plabr_0438	1.789e-32	142.0	COG1196@1|root,COG1196@2|Bacteria,2J1C6@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6203315_7	1101195.Meth11DRAFT_1464	7.851e-19	94.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6203315_10	627192.SLG_09880	9.653e-14	82.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6203315_3	1121033.AUCF01000026_gene2978	2.987e-42	160.0	COG3384@1|root,COG3384@2|Bacteria,1RIBC@1224|Proteobacteria,2UET5@28211|Alphaproteobacteria,2JX83@204441|Rhodospirillales	204441|Rhodospirillales	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
YYD3_k127_6203315_0	1121033.AUCF01000026_gene2977	3.051e-124	407.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2JWA9@204441|Rhodospirillales	204441|Rhodospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
YYD3_k127_6203315_8	234267.Acid_0107	4.563e-18	88.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
YYD3_k127_6203315_2	234267.Acid_7677	3.333e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
YYD3_k127_6203315_4	1210884.HG799466_gene12797	3.542e-37	152.0	COG0515@1|root,COG0515@2|Bacteria,2IX09@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
YYD3_k127_6208161_2	1167006.UWK_02852	7.203e-30	127.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
YYD3_k127_6208161_0	314278.NB231_07712	0.0	1407.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X2PZ@135613|Chromatiales	135613|Chromatiales	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
YYD3_k127_6208161_3	886293.Sinac_1329	3.369e-16	87.0	2CK1C@1|root,32SJA@2|Bacteria,2J05T@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6208161_1	768706.Desor_0672	5.506e-37	141.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2611G@186807|Peptococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
YYD3_k127_6220954_0	319003.Bra1253DRAFT_02817	0.0	1058.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWQB@28211|Alphaproteobacteria,3JQWC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	MA20_07280	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
YYD3_k127_6220954_2	234267.Acid_4407	1.72e-26	119.0	COG3861@1|root,COG3861@2|Bacteria,3Y5WZ@57723|Acidobacteria	57723|Acidobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
YYD3_k127_6220954_4	1121926.AXWO01000034_gene1977	6.032e-06	54.0	2DMMR@1|root,32SHV@2|Bacteria	2|Bacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
YYD3_k127_6220954_1	204669.Acid345_4475	1.253e-38	151.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
YYD3_k127_6223560_11	1116472.MGMO_53c00580	8.539e-30	124.0	COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria,1SPRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
YYD3_k127_6223560_5	661478.OP10G_2561	3.456e-99	332.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
YYD3_k127_6223560_0	204669.Acid345_2614	3.663e-171	548.0	COG2256@1|root,COG2256@2|Bacteria,3Y3F7@57723|Acidobacteria,2JIAH@204432|Acidobacteriia	204432|Acidobacteriia	L	AAA ATPase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
YYD3_k127_6223560_9	1382359.JIAL01000001_gene2758	7.153e-43	168.0	COG0566@1|root,COG0566@2|Bacteria,3Y4GM@57723|Acidobacteria,2JJ7T@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
YYD3_k127_6223560_8	415426.Hbut_0770	5.963e-48	180.0	COG0009@1|root,arCOG01952@2157|Archaea,2XPW0@28889|Crenarchaeota	28889|Crenarchaeota	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
YYD3_k127_6223560_10	1267535.KB906767_gene4032	4.287e-33	135.0	COG1434@1|root,COG1434@2|Bacteria,3Y4FT@57723|Acidobacteria,2JJ4K@204432|Acidobacteriia	204432|Acidobacteriia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
YYD3_k127_6223560_3	670292.JH26_01350	1.157e-125	411.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,1JYIK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
YYD3_k127_6223560_2	204669.Acid345_1988	9.345e-136	449.0	COG0747@1|root,COG0747@2|Bacteria,3Y44K@57723|Acidobacteria,2JHM9@204432|Acidobacteriia	204432|Acidobacteriia	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_6223560_7	530564.Psta_2542	5.207e-79	281.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_6223560_4	1210884.HG799469_gene14163	6.882e-124	412.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_6223560_6	314230.DSM3645_24005	1.71e-96	330.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_6223560_1	1123508.JH636439_gene582	1.381e-155	522.0	COG0577@1|root,COG0577@2|Bacteria,2IYHP@203682|Planctomycetes	203682|Planctomycetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6229578_1	1408452.JAGZ01000002_gene4568	0.0001961	53.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria,236GH@1762|Mycobacteriaceae	201174|Actinobacteria	C	E-Z type HEAT repeats	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
YYD3_k127_6229578_0	1297570.MESS4_360039	1.147e-76	267.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,43JF1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
YYD3_k127_6269615_1	204669.Acid345_2892	1.371e-13	79.0	COG4932@1|root,COG4932@2|Bacteria,3Y5W1@57723|Acidobacteria,2JNVI@204432|Acidobacteriia	204432|Acidobacteriia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6269615_0	234267.Acid_2629	5.439e-48	195.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
YYD3_k127_6269615_2	983545.Glaag_3512	0.0003898	47.0	COG4886@1|root,COG4886@2|Bacteria,1N4KB@1224|Proteobacteria,1RZAH@1236|Gammaproteobacteria,465K1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
YYD3_k127_6283818_0	251221.35212092	7.113e-237	749.0	COG0531@1|root,COG0531@2|Bacteria,1G1I6@1117|Cyanobacteria	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6283818_1	1403819.BATR01000118_gene4198	1.415e-58	209.0	COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YYD3_k127_6295422_2	234267.Acid_1156	5.321e-134	440.0	COG0380@1|root,COG0380@2|Bacteria,3Y3X7@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
YYD3_k127_6295422_0	234267.Acid_1157	0.0	1009.0	COG3387@1|root,COG3387@2|Bacteria,3Y42X@57723|Acidobacteria	2|Bacteria	G	PFAM Glycoside hydrolase 15-related	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
YYD3_k127_6295422_4	234267.Acid_4765	1.991e-37	145.0	COG3801@1|root,COG3801@2|Bacteria,3Y5K2@57723|Acidobacteria	57723|Acidobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
YYD3_k127_6295422_3	1340493.JNIF01000003_gene3998	2.872e-46	171.0	COG3019@1|root,COG3019@2|Bacteria	2|Bacteria	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
YYD3_k127_6295422_1	234267.Acid_7841	2.518e-208	698.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_6297001_3	349163.Acry_0301	7.225e-55	203.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,2JR80@204441|Rhodospirillales	204441|Rhodospirillales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
YYD3_k127_6297001_2	404589.Anae109_2961	5.183e-99	330.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P6Q@68525|delta/epsilon subdivisions,2WKPS@28221|Deltaproteobacteria,2YXDB@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_6297001_8	237609.PSAKL28_25430	3.081e-12	69.0	2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,1S7DW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
YYD3_k127_6297001_6	314345.SPV1_10666	1.548e-17	85.0	28UDP@1|root,2ZGIS@2|Bacteria,1QYVB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6297001_4	314345.SPV1_10636	7.551e-31	123.0	2E5JD@1|root,330AQ@2|Bacteria,1N86Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6297001_1	880072.Desac_2444	2.183e-208	664.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MQ7P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
YYD3_k127_6297001_7	246197.MXAN_0980	1.811e-14	75.0	COG1145@1|root,30Q5M@2|Bacteria,1N3E7@1224|Proteobacteria,43B9J@68525|delta/epsilon subdivisions,2X6NP@28221|Deltaproteobacteria,2Z1VA@29|Myxococcales	28221|Deltaproteobacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6297001_5	639030.JHVA01000001_gene3934	2.649e-21	99.0	COG1917@1|root,COG1917@2|Bacteria,3Y8X8@57723|Acidobacteria	57723|Acidobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
YYD3_k127_6297001_0	1267535.KB906767_gene244	4.988e-268	842.0	COG2217@1|root,COG2217@2|Bacteria,3Y39H@57723|Acidobacteria,2JHMU@204432|Acidobacteriia	204432|Acidobacteriia	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
YYD3_k127_6297001_9	1158607.UAU_04466	1.136e-06	53.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,4B0XV@81852|Enterococcaceae	91061|Bacilli	L	ATP-dependent DNA helicase RecQ	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
YYD3_k127_6310012_6	204669.Acid345_1099	6.422e-15	85.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48
YYD3_k127_6310012_2	1207063.P24_12082	9.782e-77	267.0	COG1763@1|root,COG1763@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03753,ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	-
YYD3_k127_6310012_5	682795.AciX8_3193	4.56e-24	113.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YYD3_k127_6310012_0	123899.JPQP01000018_gene203	2.942e-248	771.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,3T2U0@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
YYD3_k127_6310012_7	933262.AXAM01000008_gene1975	4.675e-13	81.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2MJ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
YYD3_k127_6310012_1	243231.GSU1425	4.544e-94	316.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,43U4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
YYD3_k127_6310012_4	1267535.KB906767_gene4618	2.833e-51	188.0	COG0558@1|root,COG0558@2|Bacteria,3Y520@57723|Acidobacteria,2JP32@204432|Acidobacteriia	204432|Acidobacteriia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
YYD3_k127_6310012_3	357808.RoseRS_1852	6.599e-73	252.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
YYD3_k127_631968_1	208439.AJAP_30140	1.638e-80	272.0	COG2267@1|root,COG2267@2|Bacteria,2H83P@201174|Actinobacteria,4DYV8@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
YYD3_k127_631968_2	237368.SCABRO_03982	9.82e-52	192.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
YYD3_k127_631968_4	1047013.AQSP01000125_gene2625	2.833e-18	90.0	COG1314@1|root,COG1314@2|Bacteria,2NPYV@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
YYD3_k127_631968_0	269799.Gmet_1948	5.682e-89	299.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,43T81@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
YYD3_k127_631968_3	869213.JCM21142_1677	1.629e-37	143.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
YYD3_k127_6332191_4	439235.Dalk_3134	3.832e-11	69.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MHYY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
YYD3_k127_6332191_2	926566.Terro_3448	4.63e-98	336.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD3_k127_6332191_0	1047013.AQSP01000140_gene2480	1.449e-132	440.0	COG0769@1|root,COG0769@2|Bacteria,2NNZM@2323|unclassified Bacteria	2|Bacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD3_k127_6332191_1	316067.Geob_0774	7.418e-132	444.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
YYD3_k127_6332191_5	1267534.KB906754_gene2739	4.92e-07	59.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria,2JJBJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
YYD3_k127_6332191_3	1254432.SCE1572_10480	9.427e-63	222.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
YYD3_k127_6335409_0	56780.SYN_00126	6.756e-122	396.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_6335409_1	933262.AXAM01000001_gene418	9.074e-19	94.0	COG0745@1|root,COG0745@2|Bacteria,1QW1Y@1224|Proteobacteria,43BS5@68525|delta/epsilon subdivisions,2X72Y@28221|Deltaproteobacteria,2MPJE@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,zinc_ribbon_4
YYD3_k127_6348967_0	234267.Acid_2215	3.553e-185	585.0	COG0673@1|root,COG0673@2|Bacteria,3Y6W6@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
YYD3_k127_6348967_2	889378.Spiaf_2393	2.72e-15	81.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
YYD3_k127_6348967_1	111780.Sta7437_1570	1.104e-67	241.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
YYD3_k127_6356702_5	1379270.AUXF01000002_gene1145	2.404e-19	98.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
YYD3_k127_6356702_1	243233.MCA0309	1.761e-57	207.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,1S3AV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heme iron utilization protein	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
YYD3_k127_6356702_6	85643.Tmz1t_1480	6.63e-05	50.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2VIFW@28216|Betaproteobacteria,2KXZS@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
YYD3_k127_6356702_3	1487953.JMKF01000074_gene3681	1.104e-39	171.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_6356702_0	1242864.D187_001429	3.73e-112	402.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1MXH7@1224|Proteobacteria,43AYG@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_6356702_2	234267.Acid_7393	8.038e-44	164.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_6360331_2	497964.CfE428DRAFT_2129	8.614e-114	373.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
YYD3_k127_6360331_1	204669.Acid345_4072	5.39e-131	434.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
YYD3_k127_6360331_0	1122604.JONR01000008_gene2284	1.01e-237	757.0	COG0154@1|root,COG0154@2|Bacteria,1NS7J@1224|Proteobacteria,1SMJ8@1236|Gammaproteobacteria,1XA2W@135614|Xanthomonadales	135614|Xanthomonadales	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
YYD3_k127_6360331_3	1121943.KB899992_gene2160	7.213e-68	240.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
YYD3_k127_6360331_6	1121943.KB899992_gene2159	3.148e-56	211.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
YYD3_k127_6360331_5	1157708.KB907450_gene5936	3.081e-57	207.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria,2VVFK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
YYD3_k127_6360331_7	1232410.KI421412_gene358	5.266e-19	93.0	2EI25@1|root,33BTK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6360331_4	234267.Acid_6920	1.874e-66	231.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	yaaI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
YYD3_k127_6365738_9	765912.Thimo_0360	8.741e-12	69.0	arCOG09511@1|root,2Z9DH@2|Bacteria,1MXRV@1224|Proteobacteria,1SEJ5@1236|Gammaproteobacteria,1WZGY@135613|Chromatiales	135613|Chromatiales	S	PFAM FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
YYD3_k127_6365738_8	102129.Lepto7375DRAFT_6947	2.472e-25	109.0	COG4319@1|root,COG4319@2|Bacteria,1G6QY@1117|Cyanobacteria,1HBIC@1150|Oscillatoriales	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
YYD3_k127_6365738_3	269799.Gmet_3460	9.103e-84	292.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD3_k127_6365738_2	903818.KI912268_gene965	2.44e-87	301.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
YYD3_k127_6365738_1	439235.Dalk_2025	2.779e-93	315.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	ybhF-C	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
YYD3_k127_6365738_0	452637.Oter_0917	3.492e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,46SF6@74201|Verrucomicrobia,3K7X0@414999|Opitutae	74201|Verrucomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_6365738_6	264732.Moth_1902	3.867e-53	199.0	COG1566@1|root,COG1566@2|Bacteria,1UJ4C@1239|Firmicutes,25EVQ@186801|Clostridia,42J6D@68295|Thermoanaerobacterales	186801|Clostridia	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
YYD3_k127_6365738_10	243231.GSU2823	6.607e-06	51.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria,43TJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
YYD3_k127_6365738_4	671143.DAMO_3042	3.355e-73	260.0	COG0177@1|root,COG0177@2|Bacteria,2NQYE@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF2400)	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF2400,EndIII_4Fe-2S,HhH-GPD
YYD3_k127_6365738_7	383372.Rcas_0886	5.399e-44	177.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
YYD3_k127_6365738_5	1303518.CCALI_01925	2.542e-72	249.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
YYD3_k127_6366927_3	105559.Nwat_1601	9.916e-10	68.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1X0J6@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4,YtkA
YYD3_k127_6366927_2	653045.Strvi_6577	7.404e-21	106.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
YYD3_k127_6366927_1	404380.Gbem_3661	4.156e-30	137.0	COG3659@1|root,COG3659@2|Bacteria,1Q0I4@1224|Proteobacteria,42WBJ@68525|delta/epsilon subdivisions,2WS5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	-	-	-	-	-	-	-	-	-	OprB
YYD3_k127_6366927_0	502025.Hoch_6837	6.47e-88	303.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
YYD3_k127_6374032_3	1183438.GKIL_0023	1.27e-21	96.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
YYD3_k127_6374032_1	1254432.SCE1572_00530	3.622e-44	168.0	COG0783@1|root,COG0783@2|Bacteria	2|Bacteria	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
YYD3_k127_6374032_4	1267535.KB906767_gene4881	5.302e-18	87.0	COG1734@1|root,COG1734@2|Bacteria,3Y85W@57723|Acidobacteria	57723|Acidobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
YYD3_k127_6374032_0	497964.CfE428DRAFT_5641	4.575e-173	549.0	COG2805@1|root,COG2805@2|Bacteria,46SY2@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_6374032_2	933262.AXAM01000001_gene419	6.985e-35	142.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MHXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
YYD3_k127_6400104_0	639282.DEFDS_1463	9.307e-168	536.0	COG0013@1|root,COG0013@2|Bacteria,2GF1K@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
YYD3_k127_6400104_3	262724.TT_C0496	9.213e-08	59.0	COG2137@1|root,COG2137@2|Bacteria,1WJTS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
YYD3_k127_6400104_1	1340493.JNIF01000003_gene2302	5.722e-20	96.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria	57723|Acidobacteria	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
YYD3_k127_6400104_5	1121422.AUMW01000027_gene423	7.591e-07	61.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,260KF@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
YYD3_k127_6400104_2	234267.Acid_1723	6.732e-16	80.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
YYD3_k127_6400104_6	234267.Acid_7711	3.141e-06	53.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria	57723|Acidobacteria	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
YYD3_k127_6400104_4	511062.GU3_07805	4.771e-07	55.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1Y44T@135624|Aeromonadales	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
YYD3_k127_6406163_5	234267.Acid_7841	8.844e-42	169.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_6406163_1	234267.Acid_7841	7.645e-160	553.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
YYD3_k127_6406163_0	46429.BV95_04154	7.99e-204	656.0	COG1629@1|root,COG4771@2|Bacteria,1R4PY@1224|Proteobacteria,2U3FF@28211|Alphaproteobacteria,2K1WN@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YYD3_k127_6406163_4	234267.Acid_4411	8.423e-42	156.0	COG0640@1|root,COG0640@2|Bacteria,3Y5ZP@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
YYD3_k127_6406163_2	234267.Acid_4410	7.406e-124	405.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
YYD3_k127_6406163_3	330214.NIDE3707	1.528e-46	171.0	COG0394@1|root,COG0394@2|Bacteria,3J1AU@40117|Nitrospirae	40117|Nitrospirae	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
YYD3_k127_6419252_5	1380394.JADL01000005_gene5673	7.814e-05	47.0	COG0725@1|root,COG0725@2|Bacteria,1RCHM@1224|Proteobacteria,2VGBX@28211|Alphaproteobacteria,2JWBR@204441|Rhodospirillales	204441|Rhodospirillales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
YYD3_k127_6419252_3	247633.GP2143_17801	2.609e-30	124.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6419252_2	861299.J421_5754	1.495e-77	273.0	2E1RX@1|root,32X1X@2|Bacteria,1ZUAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6419252_1	673860.AciM339_0552	9.515e-93	315.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
YYD3_k127_6419252_4	682795.AciX8_1220	1.358e-15	83.0	COG0586@1|root,COG0586@2|Bacteria,3Y4JN@57723|Acidobacteria,2JJ9B@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
YYD3_k127_6419252_0	1267533.KB906737_gene1874	3.547e-195	613.0	COG3285@1|root,COG3285@2|Bacteria,3Y715@57723|Acidobacteria,2JM5P@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6422210_0	1380394.JADL01000001_gene2363	9.717e-134	431.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JQVW@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
YYD3_k127_6422210_1	365046.Rta_12350	5.533e-127	424.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
YYD3_k127_6422210_3	1403819.BATR01000016_gene491	3.528e-29	119.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
YYD3_k127_6422210_2	1267535.KB906767_gene3728	3.77e-90	306.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_6434889_0	292415.Tbd_1072	1.324e-170	541.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VS7B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
YYD3_k127_6434889_1	1340493.JNIF01000003_gene1440	8.888e-164	541.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
YYD3_k127_6434889_5	317936.Nos7107_3577	2.242e-25	119.0	2DPW6@1|root,333NE@2|Bacteria,1GIFN@1117|Cyanobacteria,1HK3C@1161|Nostocales	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6434889_4	56110.Oscil6304_4725	1.208e-52	191.0	COG4278@1|root,COG4278@2|Bacteria,1G3Y0@1117|Cyanobacteria,1HA2F@1150|Oscillatoriales	1117|Cyanobacteria	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
YYD3_k127_6434889_3	627192.SLG_31400	1.647e-146	476.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_6434889_2	627192.SLG_31420	2.14e-153	497.0	COG0551@1|root,COG0551@2|Bacteria,1NU8S@1224|Proteobacteria,2TWWM@28211|Alphaproteobacteria,2K3KC@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
YYD3_k127_645337_4	255470.cbdbA1722	9.752e-35	137.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,34CPV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
YYD3_k127_645337_2	194439.CT0209	1.827e-48	180.0	COG0615@1|root,COG0615@2|Bacteria,1FE2V@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
YYD3_k127_645337_0	234267.Acid_7421	1.751e-306	979.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria	57723|Acidobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
YYD3_k127_645337_3	204669.Acid345_4225	1.888e-42	169.0	COG0760@1|root,COG0760@2|Bacteria,3Y3V9@57723|Acidobacteria,2JICA@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
YYD3_k127_645337_6	868864.Dester_0437	9.16e-17	83.0	COG1188@1|root,COG1188@2|Bacteria,2G57F@200783|Aquificae	200783|Aquificae	J	RNA-binding S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
YYD3_k127_645337_7	234267.Acid_7418	1.366e-16	85.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
YYD3_k127_645337_1	595536.ADVE02000001_gene2292	2.081e-232	728.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,36XKU@31993|Methylocystaceae	28211|Alphaproteobacteria	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
YYD3_k127_6453710_2	1267534.KB906754_gene2899	5.014e-62	221.0	COG0154@1|root,COG0154@2|Bacteria,3Y41H@57723|Acidobacteria,2JKKU@204432|Acidobacteriia	204432|Acidobacteriia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
YYD3_k127_6453710_1	204669.Acid345_1684	4.352e-227	715.0	COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria,2JMD8@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
YYD3_k127_6453710_0	204669.Acid345_1682	2.575e-313	997.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria,2JKNM@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,UnbV_ASPIC,VCBS
YYD3_k127_6455594_2	497964.CfE428DRAFT_4449	2.817e-40	164.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,46U3B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
YYD3_k127_6455594_1	324602.Caur_3409	1.377e-40	170.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
YYD3_k127_6455594_0	502025.Hoch_3262	5.222e-59	211.0	COG1721@1|root,COG1721@2|Bacteria,1NEAC@1224|Proteobacteria,43B78@68525|delta/epsilon subdivisions,2X6KP@28221|Deltaproteobacteria,2YWA8@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
YYD3_k127_6456650_0	448385.sce3007	1.596e-184	585.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
YYD3_k127_6456650_1	926569.ANT_11320	4.703e-20	103.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6456650_3	1122915.AUGY01000016_gene2383	7.593e-06	56.0	COG3766@1|root,COG3766@2|Bacteria,1V79Y@1239|Firmicutes,4HJI3@91061|Bacilli,26XGW@186822|Paenibacillaceae	91061|Bacilli	S	Domain of Unknown Function (DUF350)	yshE1	-	-	ko:K08989	-	-	-	-	ko00000	-	-	-	DUF350
YYD3_k127_6456650_2	1225184.ALXE01000019_gene4003	1.351e-15	83.0	COG0791@1|root,COG0791@2|Bacteria,1RC1D@1224|Proteobacteria,1S203@1236|Gammaproteobacteria,3W0RV@53335|Pantoea	1236|Gammaproteobacteria	M	NlpC/P60 family	-	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	NLPC_P60
YYD3_k127_6460374_4	1469607.KK073768_gene1036	3.037e-07	53.0	COG2319@1|root,COG2319@2|Bacteria,1G2PA@1117|Cyanobacteria,1HMN4@1161|Nostocales	1117|Cyanobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
YYD3_k127_6460374_2	234267.Acid_6421	3.157e-52	195.0	COG0500@1|root,COG2226@2|Bacteria,3Y8SA@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_6460374_6	234267.Acid_7271	8.385e-06	50.0	COG0421@1|root,COG0421@2|Bacteria,3Y6UP@57723|Acidobacteria	57723|Acidobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
YYD3_k127_6460374_5	1108045.GORHZ_109_00020	1.181e-06	53.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
YYD3_k127_6460374_1	1446473.JHWH01000009_gene242	7.45e-66	230.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,2PVWT@265|Paracoccus	28211|Alphaproteobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
YYD3_k127_6460374_0	234267.Acid_7844	2.447e-151	508.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,3Y2VV@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase LigD, ligase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
YYD3_k127_6460374_7	545694.TREPR_3769	0.0003901	53.0	COG4783@1|root,COG4783@2|Bacteria,2J9TB@203691|Spirochaetes	203691|Spirochaetes	M	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
YYD3_k127_6470884_1	710687.KI912270_gene1047	2.354e-70	247.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,234WR@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA18	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
YYD3_k127_6470884_0	1380394.JADL01000007_gene4673	4.324e-118	391.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	28211|Alphaproteobacteria	C	III protein, CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
YYD3_k127_6470884_2	234267.Acid_1170	1.52e-41	167.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	2|Bacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_6470884_4	640512.BC1003_4631	4.784e-08	63.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,1K0GR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
YYD3_k127_6470884_3	247633.GP2143_17791	1.325e-19	90.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6522885_2	1340493.JNIF01000003_gene3933	8.403e-23	104.0	COG1286@1|root,COG1286@2|Bacteria,3Y59W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
YYD3_k127_6522885_7	903818.KI912269_gene198	8.711e-09	59.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
YYD3_k127_6522885_3	573413.Spirs_4068	4.451e-21	106.0	COG0322@1|root,COG0322@2|Bacteria,2J69M@203691|Spirochaetes	203691|Spirochaetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YYD3_k127_6522885_1	204669.Acid345_2825	1.173e-54	204.0	COG0627@1|root,COG0627@2|Bacteria,3Y8UN@57723|Acidobacteria	57723|Acidobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
YYD3_k127_6522885_6	1123355.JHYO01000001_gene3183	6.782e-10	65.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2UDE8@28211|Alphaproteobacteria,36YKR@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
YYD3_k127_6522885_4	247490.KSU1_D0840	2.159e-20	97.0	COG0723@1|root,COG0723@2|Bacteria,2J13H@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
YYD3_k127_6522885_0	1382359.JIAL01000001_gene1831	8.172e-141	455.0	COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria,2JHY8@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
YYD3_k127_6522885_5	688269.Theth_0849	5.974e-10	62.0	COG1254@1|root,COG1254@2|Bacteria,2GDJK@200918|Thermotogae	200918|Thermotogae	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
YYD3_k127_652312_0	1047013.AQSP01000107_gene2089	3.142e-165	583.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
YYD3_k127_652312_1	1267535.KB906767_gene593	1.09e-72	249.0	COG0693@1|root,COG0693@2|Bacteria,3Y4UE@57723|Acidobacteria,2JJEW@204432|Acidobacteriia	204432|Acidobacteriia	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
YYD3_k127_652312_2	1379270.AUXF01000002_gene1400	8.676e-13	78.0	29X7E@1|root,30IWN@2|Bacteria,1ZV4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
YYD3_k127_6524572_6	234267.Acid_7680	1.493e-25	108.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6524572_4	234267.Acid_7680	2.343e-37	148.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_6524572_5	497964.CfE428DRAFT_5853	9.464e-37	147.0	COG2146@1|root,COG2146@2|Bacteria,46T9C@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske_2
YYD3_k127_6524572_0	497964.CfE428DRAFT_5852	0.0	1319.0	COG1251@1|root,COG1251@2|Bacteria,46SIV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	BFD-like [2Fe-2S] binding domain	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
YYD3_k127_6524572_3	497964.CfE428DRAFT_5851	1.017e-39	154.0	COG0723@1|root,COG0723@2|Bacteria,46WMV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM Rieske 2Fe-2S domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
YYD3_k127_6524572_2	497964.CfE428DRAFT_5850	8.467e-91	302.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_4
YYD3_k127_6524572_1	497964.CfE428DRAFT_5849	6.357e-191	599.0	COG0243@1|root,COG0243@2|Bacteria,46U1H@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
YYD3_k127_6530663_2	671143.DAMO_0850	1.122e-124	407.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YYD3_k127_6530663_1	1267533.KB906740_gene212	2.56e-130	425.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	57723|Acidobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
YYD3_k127_6530663_4	1267533.KB906740_gene211	4.116e-39	158.0	COG0671@1|root,COG0671@2|Bacteria,3Y8KF@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
YYD3_k127_6530663_3	448385.sce4012	6.955e-54	196.0	COG4300@1|root,COG4300@2|Bacteria,1PNFJ@1224|Proteobacteria,434SI@68525|delta/epsilon subdivisions,2WZ3K@28221|Deltaproteobacteria,2Z197@29|Myxococcales	28221|Deltaproteobacteria	P	Cadmium resistance transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cad
YYD3_k127_6530663_0	211165.AJLN01000050_gene5337	2.72e-219	694.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JK4Q@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
YYD3_k127_6530663_5	1123389.ATXJ01000001_gene715	3.97e-06	49.0	COG1529@1|root,COG1529@2|Bacteria,1WM6R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
YYD3_k127_6553888_2	864069.MicloDRAFT_00046540	7.666e-28	115.0	COG2323@1|root,COG2323@2|Bacteria,1PKVB@1224|Proteobacteria,2UZH7@28211|Alphaproteobacteria,1JUD7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
YYD3_k127_6553888_1	344747.PM8797T_02574	3.799e-73	256.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2IZBI@203682|Planctomycetes	203682|Planctomycetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
YYD3_k127_6553888_0	105559.Nwat_1349	5.958e-227	710.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X04R@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K15408	ko00190,map00190	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX1
YYD3_k127_6559562_12	595537.Varpa_5594	7.64e-31	141.0	28M2S@1|root,2ZAH5@2|Bacteria,1MVH5@1224|Proteobacteria,2VM5E@28216|Betaproteobacteria,4AH42@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6559562_1	237368.SCABRO_01577	4.296e-158	510.0	COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_6559562_0	1382359.JIAL01000001_gene2318	1.535e-300	941.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria,2JHMJ@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
YYD3_k127_6559562_14	1492738.FEM21_06780	3.613e-29	130.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1HYR6@117743|Flavobacteriia,2NTXF@237|Flavobacterium	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
YYD3_k127_6559562_4	1183438.GKIL_0032	3.2e-84	293.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	2|Bacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74	ko:K08070,ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_6559562_8	240015.ACP_0422	1.693e-68	239.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria,2JJ36@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
YYD3_k127_6559562_13	391625.PPSIR1_04398	1.307e-30	124.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
YYD3_k127_6559562_9	1242864.D187_008379	4.37e-60	220.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YYD3_k127_6559562_2	1283284.AZUK01000001_gene56	3.382e-137	441.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1Y606@135624|Aeromonadales	135624|Aeromonadales	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
YYD3_k127_6559562_10	502025.Hoch_3949	7.126e-60	215.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2X3AE@28221|Deltaproteobacteria,2YV4E@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
YYD3_k127_6559562_3	330214.NIDE2516	1.767e-108	362.0	COG0006@1|root,COG0006@2|Bacteria,3J0R0@40117|Nitrospirae	40117|Nitrospirae	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YYD3_k127_6559562_6	204669.Acid345_4119	4.658e-79	272.0	COG1235@1|root,COG1235@2|Bacteria	2|Bacteria	P	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
YYD3_k127_6559562_5	1121439.dsat_2617	6.323e-81	279.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2M8CF@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
YYD3_k127_6559562_11	1242864.D187_001666	3.8e-43	169.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
YYD3_k127_6559562_15	1380380.JIAX01000006_gene1085	1.169e-14	82.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
YYD3_k127_6559562_7	330214.NIDE0254	8.368e-70	244.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
YYD3_k127_658707_0	1165096.ARWF01000001_gene440	7.807e-48	183.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_658707_1	987059.RBXJA2T_10906	8.2e-21	100.0	COG5628@1|root,COG5628@2|Bacteria	2|Bacteria	J	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
YYD3_k127_658707_2	270374.MELB17_14416	1.189e-10	66.0	COG4118@1|root,COG4118@2|Bacteria,1NAEH@1224|Proteobacteria,1SS0R@1236|Gammaproteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
YYD3_k127_6604150_2	404589.Anae109_2737	2.825e-76	258.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD3_k127_6604150_3	313628.LNTAR_01145	3.185e-58	210.0	COG2131@1|root,COG2131@2|Bacteria	2|Bacteria	F	dCMP deaminase activity	dcdA	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
YYD3_k127_6604150_0	1403819.BATR01000150_gene5078	5.881e-115	382.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6604150_1	240016.ABIZ01000001_gene3548	8.974e-111	370.0	COG0577@1|root,COG0577@2|Bacteria,46UT6@74201|Verrucomicrobia,2IVGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_6606820_5	381666.H16_B0574	3.009e-35	139.0	COG0500@1|root,COG2226@2|Bacteria,1REVA@1224|Proteobacteria,2WEYJ@28216|Betaproteobacteria,1KGHX@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
YYD3_k127_6606820_2	61647.LG71_20670	9.482e-65	229.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cobA	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
YYD3_k127_6606820_4	1049564.TevJSym_ax00380	7.44e-43	164.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1J4IM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_3999	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
YYD3_k127_6606820_6	1408424.JHYI01000010_gene823	3.39e-33	139.0	COG1587@1|root,COG1587@2|Bacteria,1V0K1@1239|Firmicutes,4HFWP@91061|Bacilli,1ZCRM@1386|Bacillus	91061|Bacilli	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
YYD3_k127_6606820_8	195250.CM001776_gene1729	1.988e-22	104.0	2DUA0@1|root,33PJB@2|Bacteria,1GD0Q@1117|Cyanobacteria,1H0Y9@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6606820_0	502025.Hoch_5119	5.32e-291	911.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
YYD3_k127_6606820_3	1150469.RSPPHO_02406	1.848e-51	186.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria	1224|Proteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
YYD3_k127_6606820_1	518766.Rmar_0105	1.959e-101	339.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1FINU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
YYD3_k127_6606820_7	323098.Nwi_2419	1.25e-22	101.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3JR83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
YYD3_k127_6607376_0	1379698.RBG1_1C00001G0607	2.078e-78	289.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
YYD3_k127_6607376_2	1121904.ARBP01000003_gene6195	2.406e-36	156.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,47KAI@768503|Cytophagia	976|Bacteroidetes	E	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
YYD3_k127_6607376_1	204669.Acid345_3981	1.66e-66	230.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria,2JN3W@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
YYD3_k127_6607376_3	583355.Caka_2246	4.399e-15	76.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,3K9P3@414999|Opitutae	414999|Opitutae	S	PFAM nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
YYD3_k127_6613717_2	247490.KSU1_C0529	2.203e-122	402.0	COG0265@1|root,COG0265@2|Bacteria,2IYN3@203682|Planctomycetes	203682|Planctomycetes	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
YYD3_k127_6613717_0	1124780.ANNU01000044_gene525	5.443e-293	919.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
YYD3_k127_6613717_3	1353529.M899_3035	6.547e-87	297.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,42QWY@68525|delta/epsilon subdivisions,2MSQP@213481|Bdellovibrionales,2WMZD@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	LysR substrate binding domain	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
YYD3_k127_6613717_5	1121920.AUAU01000007_gene500	1.631e-74	253.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria	57723|Acidobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
YYD3_k127_6613717_1	391625.PPSIR1_36697	4.36e-213	669.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
YYD3_k127_6613717_8	404589.Anae109_0813	1.05e-51	188.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
YYD3_k127_6613717_4	1267534.KB906759_gene1657	1.181e-84	287.0	COG4700@1|root,COG4700@2|Bacteria,3Y7KZ@57723|Acidobacteria,2JMTS@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6613717_6	234267.Acid_5241	8.287e-65	232.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6613717_7	331113.SNE_A20960	2.932e-63	221.0	COG1670@1|root,COG1670@2|Bacteria,2JH3B@204428|Chlamydiae	204428|Chlamydiae	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
YYD3_k127_6613717_12	1123377.AUIV01000026_gene572	2.215e-05	55.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S2VT@1236|Gammaproteobacteria,1XCIY@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0810 Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
YYD3_k127_6613717_9	234267.Acid_2698	9.332e-45	171.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_6613717_10	555793.WSK_4047	1.347e-23	113.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6613717_11	551789.ATVJ01000001_gene1039	6.26e-15	81.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6650819_2	1210884.HG799469_gene14163	3.876e-146	488.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
YYD3_k127_6650819_0	1382304.JNIL01000001_gene2716	0.0	1056.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,2786V@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
YYD3_k127_6650819_1	234267.Acid_5783	6.046e-236	743.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
YYD3_k127_6650819_7	1267533.KB906737_gene1974	5.16e-13	82.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
YYD3_k127_6650819_5	1242864.D187_000201	7.916e-66	233.0	COG4221@1|root,COG4221@2|Bacteria,1QXEV@1224|Proteobacteria	1224|Proteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
YYD3_k127_6650819_4	1267533.KB906738_gene2330	9.71e-101	344.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
YYD3_k127_6650819_3	700598.Niako_2129	2.327e-145	468.0	COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,1ISZR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the glutaminase family	glsA	GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
YYD3_k127_6650819_6	1396141.BATP01000023_gene555	1.956e-61	217.0	COG4307@1|root,COG4307@2|Bacteria,46U5T@74201|Verrucomicrobia,2IVFH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
YYD3_k127_6673442_3	134676.ACPL_2191	1.1e-09	59.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4DG36@85008|Micromonosporales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
YYD3_k127_6673442_2	1476583.DEIPH_ctg011orf0192	3.073e-15	85.0	COG3121@1|root,COG3121@2|Bacteria,1WITE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6673442_5	1330700.JQNC01000003_gene720	0.0003677	54.0	COG1361@1|root,COG1361@2|Bacteria,1WI4N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
YYD3_k127_6673442_0	886293.Sinac_7482	7.29e-145	470.0	COG0438@1|root,COG0438@2|Bacteria,2IY41@203682|Planctomycetes	203682|Planctomycetes	M	Gkycosyl transferase family 4 group	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_3,Glycos_transf_1
YYD3_k127_6673442_1	595460.RRSWK_02125	1.149e-18	100.0	COG1357@1|root,COG1511@1|root,COG2931@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1511@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,2IZ0P@203682|Planctomycetes	203682|Planctomycetes	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Laminin_G_3
YYD3_k127_6685_0	345341.KUTG_00163	3.957e-72	271.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,2I3FC@201174|Actinobacteria,4EFCV@85010|Pseudonocardiales	201174|Actinobacteria	Q	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
YYD3_k127_6722886_15	1461580.CCAS010000002_gene354	9.558e-13	73.0	298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1ZH6F@1386|Bacillus	91061|Bacilli	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
YYD3_k127_6722886_11	292459.STH292	6.018e-29	127.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,24BFK@186801|Clostridia	186801|Clostridia	G	BadF BadG BcrA BcrD	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
YYD3_k127_6722886_1	204669.Acid345_4231	1.052e-229	733.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
YYD3_k127_6722886_3	404589.Anae109_3354	1.622e-79	287.0	COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
YYD3_k127_6722886_0	1382359.JIAL01000001_gene807	8.272e-286	887.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
YYD3_k127_6722886_6	1306174.JODP01000009_gene6568	9.599e-57	209.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
YYD3_k127_6722886_13	448385.sce0426	4.46e-23	103.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,42SFZ@68525|delta/epsilon subdivisions,2WPY5@28221|Deltaproteobacteria,2Z0Z7@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
YYD3_k127_6722886_10	1267535.KB906767_gene2360	6.892e-38	146.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
YYD3_k127_6722886_4	279010.BL00774	4.089e-76	264.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
YYD3_k127_6722886_12	497964.CfE428DRAFT_4951	5.97e-25	110.0	COG5485@1|root,COG5485@2|Bacteria,46T9K@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
YYD3_k127_6722886_8	871963.Desdi_1151	2.081e-53	198.0	COG0755@1|root,COG0755@2|Bacteria,1V4A6@1239|Firmicutes,24IWH@186801|Clostridia,263XX@186807|Peptococcaceae	186801|Clostridia	O	ABC-type transport system involved in cytochrome c biogenesis, permease component	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
YYD3_k127_6722886_9	552811.Dehly_0439	1.735e-46	176.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
YYD3_k127_6722886_7	522772.Dacet_0332	8.92e-54	200.0	COG1131@1|root,COG1131@2|Bacteria,2GERZ@200930|Deferribacteres	200930|Deferribacteres	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
YYD3_k127_6722886_17	234267.Acid_4234	2.045e-10	68.0	2EFR0@1|root,339H2@2|Bacteria,3Y5M9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6722886_14	204669.Acid345_3206	1.107e-19	95.0	COG3088@1|root,COG3088@2|Bacteria,3Y4YV@57723|Acidobacteria,2JJM2@204432|Acidobacteriia	204432|Acidobacteriia	O	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
YYD3_k127_6722886_2	240015.ACP_2781	4.257e-190	615.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria,2JHQR@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
YYD3_k127_6722886_16	1340493.JNIF01000003_gene4698	1.983e-10	63.0	COG2332@1|root,COG2332@2|Bacteria,3Y57C@57723|Acidobacteria	57723|Acidobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
YYD3_k127_6722969_2	296591.Bpro_2837	2.508e-140	449.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VIEI@28216|Betaproteobacteria,4AARS@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.2.1.43,4.3.3.7	ko:K01714,ko:K13876	ko00053,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02278,R10147	RC00429,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
YYD3_k127_6722969_9	1122176.KB903533_gene2257	1.368e-11	70.0	28R0A@1|root,2ZDF0@2|Bacteria,4P70A@976|Bacteroidetes,1IZF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6722969_6	1267533.KB906736_gene1100	5.047e-43	158.0	29WUP@1|root,30IG4@2|Bacteria,3Y82K@57723|Acidobacteria	57723|Acidobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6722969_8	1227739.Hsw_1430	7.637e-34	145.0	COG0457@1|root,COG0457@2|Bacteria,4NP5N@976|Bacteroidetes,47RGN@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
YYD3_k127_6722969_7	278963.ATWD01000002_gene983	3.019e-41	162.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD3_k127_6722969_0	1000565.METUNv1_02392	1.62e-213	678.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KYIX@206389|Rhodocyclales	206389|Rhodocyclales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
YYD3_k127_6722969_1	292459.STH2751	3.446e-176	569.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,24A64@186801|Clostridia	186801|Clostridia	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
YYD3_k127_6722969_4	644966.Tmar_0709	4.211e-102	343.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCDT@538999|Clostridiales incertae sedis	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1	-	-	ABC_tran,TOBE_2
YYD3_k127_6722969_3	644283.Micau_3788	4.948e-108	362.0	COG1840@1|root,COG1840@2|Bacteria,2HV6S@201174|Actinobacteria,4DGSZ@85008|Micromonosporales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
YYD3_k127_6722969_5	1340493.JNIF01000003_gene4130	1.065e-59	229.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NZ@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
YYD3_k127_674350_3	1267535.KB906767_gene2802	1.011e-60	214.0	COG0443@1|root,COG0443@2|Bacteria,3Y2XU@57723|Acidobacteria,2JHT1@204432|Acidobacteriia	204432|Acidobacteriia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
YYD3_k127_674350_0	1382359.JIAL01000001_gene2461	2.299e-102	346.0	COG0484@1|root,COG0484@2|Bacteria,3Y2XW@57723|Acidobacteria,2JHWV@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
YYD3_k127_674350_5	1267534.KB906754_gene2696	6.683e-39	154.0	COG0789@1|root,COG0789@2|Bacteria,3Y4KX@57723|Acidobacteria,2JJA1@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
YYD3_k127_674350_4	479434.Sthe_1849	5.718e-58	211.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27Y3K@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
YYD3_k127_674350_2	1499967.BAYZ01000186_gene3949	2.939e-63	226.0	COG1484@1|root,COG1484@2|Bacteria,2NQ23@2323|unclassified Bacteria	2|Bacteria	L	IstB-like ATP binding protein	dnaC	-	3.4.21.53	ko:K02315,ko:K04076	-	-	-	-	ko00000,ko01000,ko01002,ko03032	-	-	-	AAA,IstB_IS21,Lon_C
YYD3_k127_674350_1	278963.ATWD01000001_gene1561	9.246e-85	302.0	COG2234@1|root,COG2234@2|Bacteria,3Y46R@57723|Acidobacteria,2JICT@204432|Acidobacteriia	204432|Acidobacteriia	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
YYD3_k127_674350_6	311424.DhcVS_881	1.895e-22	103.0	COG0348@1|root,COG0348@2|Bacteria,2GB0I@200795|Chloroflexi,34DPT@301297|Dehalococcoidia	301297|Dehalococcoidia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
YYD3_k127_6750379_3	471857.Svir_27400	0.000158	45.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4DYX2@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD3_k127_6750379_2	402881.Plav_2425	9.199e-08	63.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,1JPB0@119043|Rhodobiaceae	28211|Alphaproteobacteria	D	POTRA domain, FtsQ-type	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
YYD3_k127_6750379_1	1144275.COCOR_06090	1.684e-116	387.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
YYD3_k127_6750379_0	1047013.AQSP01000140_gene2471	4.777e-119	391.0	COG0206@1|root,COG0206@2|Bacteria,2NNSU@2323|unclassified Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
YYD3_k127_6755083_2	234267.Acid_0120	4.877e-120	402.0	COG1007@1|root,COG1007@2|Bacteria,3Y3PV@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
YYD3_k127_6755083_1	706587.Desti_2760	3.411e-180	577.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
YYD3_k127_6755083_0	1125863.JAFN01000001_gene2410	6.645e-211	673.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
YYD3_k127_6755083_8	639030.JHVA01000001_gene776	3.096e-32	128.0	COG0713@1|root,COG0713@2|Bacteria,3Y4XI@57723|Acidobacteria,2JJIM@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
YYD3_k127_6755083_9	204669.Acid345_1307	2.6e-30	126.0	COG0839@1|root,COG0839@2|Bacteria,3Y4I4@57723|Acidobacteria,2JJ8B@204432|Acidobacteriia	204432|Acidobacteriia	C	plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
YYD3_k127_6755083_4	525904.Tter_1537	1.351e-104	350.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
YYD3_k127_6755083_7	682795.AciX8_1390	4.136e-43	169.0	COG1905@1|root,COG1905@2|Bacteria,3Y4SI@57723|Acidobacteria,2JJDP@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
YYD3_k127_6755083_3	1340493.JNIF01000003_gene2305	6.205e-114	377.0	COG2022@1|root,COG2022@2|Bacteria,3Y2YY@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
YYD3_k127_6755083_10	234267.Acid_5657	1.184e-07	60.0	COG5349@1|root,COG5349@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF983)	MA20_36345	-	-	-	-	-	-	-	-	-	-	-	DUF983
YYD3_k127_6755083_6	234267.Acid_3194	2.279e-64	226.0	COG1666@1|root,COG1666@2|Bacteria,3Y4I3@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
YYD3_k127_6755083_5	395961.Cyan7425_2336	5.685e-72	272.0	COG2202@1|root,COG3290@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3920@2|Bacteria,1GHCI@1117|Cyanobacteria,3KKV1@43988|Cyanothece	1117|Cyanobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9
YYD3_k127_677477_1	330214.NIDE0758	2.716e-111	367.0	COG0472@1|root,COG0472@2|Bacteria,3J0C4@40117|Nitrospirae	40117|Nitrospirae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
YYD3_k127_677477_0	682795.AciX8_3881	1.119e-112	379.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD3_k127_677477_2	204669.Acid345_3630	1.767e-100	339.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
YYD3_k127_677477_3	404380.Gbem_0491	1.082e-93	319.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,43UB0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
YYD3_k127_677477_4	443144.GM21_0509	1.291e-27	113.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
YYD3_k127_6787914_4	1379270.AUXF01000001_gene2300	6.08e-33	137.0	29X7K@1|root,30IWU@2|Bacteria,1ZUTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_6787914_3	1038866.KB902802_gene7024	9.654e-36	145.0	COG0251@1|root,COG0251@2|Bacteria,1RB9R@1224|Proteobacteria,2U63U@28211|Alphaproteobacteria,3JYEU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	MA20_21375	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
YYD3_k127_6787914_5	459495.SPLC1_S208750	1.015e-25	111.0	COG2402@1|root,COG2402@2|Bacteria,1G79E@1117|Cyanobacteria,1HBMU@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
YYD3_k127_6787914_0	309801.trd_1309	9.792e-151	486.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi,27YS0@189775|Thermomicrobia	189775|Thermomicrobia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
YYD3_k127_6787914_1	472759.Nhal_2071	2.908e-94	314.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
YYD3_k127_6787914_2	378806.STAUR_5032	5.086e-45	171.0	COG0637@1|root,COG0637@2|Bacteria,1QX9J@1224|Proteobacteria,43C2S@68525|delta/epsilon subdivisions,2X7DC@28221|Deltaproteobacteria,2Z3FR@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD
YYD3_k127_6787914_6	438753.AZC_2572	2.798e-19	97.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3EYST@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Trypsin	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
YYD3_k127_6812149_5	671143.DAMO_2841	1.415e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_6812149_1	1267534.KB906756_gene561	1.351e-171	556.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
YYD3_k127_6812149_0	1382359.JIAL01000001_gene699	2.537e-207	661.0	COG1132@1|root,COG1132@2|Bacteria,3Y2ZR@57723|Acidobacteria,2JHJA@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
YYD3_k127_6812149_3	751945.Theos_1289	2.834e-51	192.0	COG4221@1|root,COG4221@2|Bacteria,1WMUB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
YYD3_k127_6812149_2	1382359.JIAL01000001_gene618	1.871e-127	438.0	COG2844@1|root,COG2844@2|Bacteria,3Y2FJ@57723|Acidobacteria,2JI19@204432|Acidobacteriia	204432|Acidobacteriia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
YYD3_k127_6812149_4	316057.RPD_0449	2.161e-38	147.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,3JYV3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
YYD3_k127_6817440_3	671143.DAMO_2863	1.303e-15	86.0	COG2096@1|root,COG2096@2|Bacteria,2NPP8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	pduO	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
YYD3_k127_6817440_2	743836.AYNA01000022_gene2185	1.841e-35	141.0	COG1917@1|root,COG1917@2|Bacteria,1QEE2@1224|Proteobacteria,2UDNV@28211|Alphaproteobacteria,3708Y@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
YYD3_k127_6817440_0	56780.SYN_01954	1.668e-62	236.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
YYD3_k127_6817440_1	497964.CfE428DRAFT_1672	4.556e-62	218.0	COG0128@1|root,COG0128@2|Bacteria	2|Bacteria	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	-	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,EPSP_synthase
YYD3_k127_6817440_4	639030.JHVA01000001_gene848	4.025e-09	60.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria,2JKPI@204432|Acidobacteriia	204432|Acidobacteriia	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_6825264_2	1267535.KB906767_gene3577	3.4e-24	114.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
YYD3_k127_6825264_1	204669.Acid345_3970	7.634e-25	107.0	2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6825264_0	1267534.KB906754_gene3411	1.135e-33	137.0	2ADQJ@1|root,313FX@2|Bacteria,3Y7U5@57723|Acidobacteria,2JN16@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_6880102_1	1499967.BAYZ01000178_gene4651	3.588e-90	312.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
YYD3_k127_6880102_3	401053.AciPR4_3582	1.801e-20	101.0	COG5662@1|root,COG5662@2|Bacteria,3Y4JS@57723|Acidobacteria,2JJ7U@204432|Acidobacteriia	204432|Acidobacteriia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
YYD3_k127_6880102_2	1340493.JNIF01000003_gene2787	9.982e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_6880102_0	632335.Calkr_1768	9.978e-128	426.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,42FCM@68295|Thermoanaerobacterales	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
YYD3_k127_6880102_4	404380.Gbem_3402	4.571e-15	80.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,43TN9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
YYD3_k127_703865_1	1121930.AQXG01000002_gene1944	2.289e-51	196.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SHD1
YYD3_k127_703865_0	234267.Acid_5242	6.081e-166	547.0	COG0557@1|root,COG0557@2|Bacteria,3Y3TF@57723|Acidobacteria	57723|Acidobacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
YYD3_k127_703865_2	1384065.JAGS01000001_gene1149	3.871e-12	68.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
YYD3_k127_705390_0	382464.ABSI01000010_gene3621	4.861e-56	198.0	COG2960@1|root,COG2960@2|Bacteria,46UCE@74201|Verrucomicrobia,2IVAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
YYD3_k127_705390_1	1007103.AFHW01000182_gene757	1.56e-16	91.0	COG0457@1|root,COG0457@2|Bacteria,1TT4Q@1239|Firmicutes,4HISG@91061|Bacilli,26S39@186822|Paenibacillaceae	91061|Bacilli	S	Cell wall assembly	-	-	-	-	-	-	-	-	-	-	-	-	Imm51,SUKH_6,TPR_2,TPR_8
YYD3_k127_707970_1	234267.Acid_4464	4.683e-58	216.0	COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	glgE	-	2.4.1.18,2.4.99.16	ko:K00700,ko:K07214,ko:K16147	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09994	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3416,Esterase
YYD3_k127_707970_0	667014.Thein_1717	1.494e-169	554.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
YYD3_k127_710194_1	640081.Dsui_2224	1.034e-17	86.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria,2KXN3@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
YYD3_k127_710194_2	1541065.JRFE01000057_gene6338	0.0003717	49.0	COG0845@1|root,COG0845@2|Bacteria,1G8SJ@1117|Cyanobacteria,3VJJK@52604|Pleurocapsales	1117|Cyanobacteria	M	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
YYD3_k127_710194_0	1230343.CANP01000044_gene3403	1.136e-218	717.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1JDFS@118969|Legionellales	118969|Legionellales	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
YYD3_k127_725921_0	497964.CfE428DRAFT_1875	5.314e-15	79.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,FGE-sulfatase,Metallophos,NACHT,PEGA,Pkinase
YYD3_k127_736259_0	1267533.KB906736_gene1246	5.144e-73	268.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
YYD3_k127_739877_2	1082931.KKY_2223	7.208e-67	235.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,3N7SA@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
YYD3_k127_739877_0	234267.Acid_0260	3.78e-246	771.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Tannase
YYD3_k127_739877_3	1121481.AUAS01000004_gene1383	7.437e-49	188.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,47M41@768503|Cytophagia	976|Bacteroidetes	S	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,Peptidase_S9
YYD3_k127_739877_4	926549.KI421517_gene3213	7.929e-33	131.0	COG2259@1|root,COG2259@2|Bacteria,4PB3J@976|Bacteroidetes,47V4B@768503|Cytophagia	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
YYD3_k127_739877_1	247633.GP2143_17791	6.848e-69	244.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_776353_0	1396141.BATP01000022_gene456	2.513e-124	418.0	COG0514@1|root,COG0514@2|Bacteria,46U82@74201|Verrucomicrobia,2ITT4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
YYD3_k127_776353_1	497964.CfE428DRAFT_2876	4.215e-80	271.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
YYD3_k127_776353_2	671143.DAMO_1554	3.337e-28	117.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
YYD3_k127_786762_1	207559.Dde_1366	1.889e-70	252.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2M7ZM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
YYD3_k127_786762_2	1267535.KB906767_gene5325	5.869e-69	243.0	COG1136@1|root,COG1136@2|Bacteria,3Y412@57723|Acidobacteria,2JIJG@204432|Acidobacteriia	204432|Acidobacteriia	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
YYD3_k127_786762_0	234267.Acid_2278	3.993e-153	487.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
YYD3_k127_851095_4	1267535.KB906767_gene948	2.224e-75	265.0	COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,3Y49J@57723|Acidobacteria,2JKA2@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
YYD3_k127_851095_0	861299.J421_5876	4.43e-284	895.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_851095_1	1267535.KB906767_gene632	1.258e-114	374.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
YYD3_k127_851095_2	1340493.JNIF01000003_gene4404	5.414e-113	377.0	COG0845@1|root,COG0845@2|Bacteria,3Y2FV@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
YYD3_k127_851095_3	234267.Acid_6478	3.484e-105	348.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
YYD3_k127_851095_7	1218108.KB908294_gene2109	1.834e-13	81.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
YYD3_k127_851095_6	864702.OsccyDRAFT_4216	7.162e-24	105.0	COG3695@1|root,COG3695@2|Bacteria,1G82G@1117|Cyanobacteria,1HCND@1150|Oscillatoriales	1117|Cyanobacteria	L	Methylated dna-protein cysteine methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
YYD3_k127_851095_5	32057.KB217481_gene8471	1.673e-28	121.0	COG0328@1|root,COG1539@1|root,COG4474@1|root,COG0328@2|Bacteria,COG1539@2|Bacteria,COG4474@2|Bacteria,1GACX@1117|Cyanobacteria	1117|Cyanobacteria	H	RNA-DNA hybrid ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_852284_1	1121289.JHVL01000006_gene2854	2.83e-116	387.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia	186801|Clostridia	C	acetaldehyde dehydrogenase (acetylating)	eutE	-	1.2.1.10,1.2.1.76,1.2.1.81,1.2.1.87	ko:K00132,ko:K13922,ko:K15515,ko:K18119	ko00620,ko00640,ko00650,ko01100,ko01120,ko01200,map00620,map00640,map00650,map01100,map01120,map01200	-	R00228,R01172,R09097,R09280	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
YYD3_k127_852284_7	1502852.FG94_03180	2.762e-24	108.0	COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_852284_11	555793.WSK_2874	9.42e-11	70.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_852284_12	234267.Acid_6744	1.458e-05	58.0	COG1452@1|root,COG1934@1|root,COG1452@2|Bacteria,COG1934@2|Bacteria,3Y388@57723|Acidobacteria	57723|Acidobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
YYD3_k127_852284_2	1267535.KB906767_gene3608	3.995e-98	327.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria,2JHPV@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
YYD3_k127_852284_0	234267.Acid_7397	9.743e-142	467.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
YYD3_k127_852284_10	1499967.BAYZ01000065_gene6104	5.895e-18	87.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
YYD3_k127_852284_4	682795.AciX8_1907	4.23e-84	289.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
YYD3_k127_852284_5	1337936.IJ00_05855	6.798e-54	197.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
YYD3_k127_852284_8	136993.KB900627_gene392	8.611e-24	114.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_852284_9	883126.HMPREF9710_00863	8.397e-19	99.0	2CK8Q@1|root,31PVK@2|Bacteria,1RIRH@1224|Proteobacteria,2VUMH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_852284_3	1121920.AUAU01000004_gene800	3.864e-88	308.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
YYD3_k127_852284_6	886293.Sinac_4875	2.898e-48	182.0	COG2755@1|root,COG2755@2|Bacteria,2IZ2H@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
YYD3_k127_858223_0	583355.Caka_2045	2.889e-193	659.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
YYD3_k127_866455_1	1124983.PFLCHA0_c20750	6.111e-38	155.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QU2N@1224|Proteobacteria,1RYA1@1236|Gammaproteobacteria,1YT9S@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	VP1463	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,NAD_binding_8
YYD3_k127_866455_0	1287276.X752_28670	3.662e-102	346.0	COG1216@1|root,COG4372@1|root,COG1216@2|Bacteria,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	ebh	-	2.1.1.80,3.1.1.61	ko:K02557,ko:K07484,ko:K13924,ko:K21471	ko02020,ko02030,ko02040,map02020,map02030,map02040	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02000,ko02022,ko02035	1.A.30.1	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,Glyco_trans_1_4,Glycos_transf_2,LZ_Tnp_IS66,zf-IS66
YYD3_k127_8821_0	234267.Acid_2554	1.534e-174	559.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
YYD3_k127_8821_2	1120950.KB892775_gene1163	2.368e-28	117.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4DRIH@85009|Propionibacteriales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
YYD3_k127_8821_1	886293.Sinac_6665	7.748e-155	498.0	COG0498@1|root,COG0498@2|Bacteria,2IXWR@203682|Planctomycetes	203682|Planctomycetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
YYD3_k127_88965_3	204669.Acid345_3335	1.36e-22	112.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
YYD3_k127_88965_2	1267534.KB906755_gene4069	2.585e-31	131.0	COG3794@1|root,COG3794@2|Bacteria,3Y4UD@57723|Acidobacteria,2JJH0@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_88965_0	234267.Acid_3938	5.52e-175	582.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
YYD3_k127_88965_1	1173024.KI912151_gene1723	5.179e-55	203.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,1JIKW@1189|Stigonemataceae	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
YYD3_k127_892174_4	1125973.JNLC01000014_gene2522	3.241e-15	85.0	COG3258@1|root,COG3258@2|Bacteria,1R0F2@1224|Proteobacteria,2TYQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
YYD3_k127_892174_3	1267534.KB906754_gene3732	4.265e-19	94.0	2DTV5@1|root,33MT0@2|Bacteria,3Y5UW@57723|Acidobacteria,2JNBS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_892174_1	794903.OPIT5_07200	3.464e-45	178.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_892174_0	1346791.M529_19040	3.742e-164	536.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales	204457|Sphingomonadales	CG	Dehydrogenase	-	-	1.1.9.1,1.17.2.2	ko:K17760,ko:K21676	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
YYD3_k127_892174_2	748280.NH8B_3286	4.181e-21	98.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,2KQJT@206351|Neisseriales	206351|Neisseriales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
YYD3_k127_900945_0	661478.OP10G_0425	1.558e-59	223.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K03296,ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	ACR_tran,OEP
YYD3_k127_921202_0	330214.NIDE1376	5.323e-177	578.0	COG1391@1|root,COG2844@1|root,COG1391@2|Bacteria,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89	ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371	ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020	M00017,M00018	R00243,R01773,R01775	RC00006,RC00087,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	GlnD_UR_UTase,GlnE,HD
YYD3_k127_921202_2	330214.NIDE1377	3.339e-110	376.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
YYD3_k127_921202_1	713587.THITH_04720	1.409e-147	474.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,1SM99@1236|Gammaproteobacteria,1X0K8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_921202_4	1267535.KB906767_gene648	1.062e-41	160.0	COG3795@1|root,COG3795@2|Bacteria,3Y8FZ@57723|Acidobacteria,2JNHB@204432|Acidobacteriia	204432|Acidobacteriia	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
YYD3_k127_921202_5	497964.CfE428DRAFT_5623	8.183e-35	139.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
YYD3_k127_921202_6	136993.KB900627_gene392	4.579e-32	136.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_921202_7	1340493.JNIF01000003_gene2122	4.656e-28	118.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_921202_3	1157708.KB907450_gene5321	8.764e-78	268.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2VJ7W@28216|Betaproteobacteria,4ADUX@80864|Comamonadaceae	28216|Betaproteobacteria	P	extracellular solute-binding protein, family 1	-	-	5.3.3.7	ko:K22003	ko00660,map00660	-	R02244	RC00668	ko00000,ko00001,ko01000	-	-	-	SBP_bac_11
YYD3_k127_932166_6	1357272.AVEO02000126_gene2602	9.998e-17	93.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
YYD3_k127_932166_1	46429.BV95_03401	9.636e-94	327.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,2K23S@204457|Sphingomonadales	204457|Sphingomonadales	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
YYD3_k127_932166_2	1040989.AWZU01000001_gene5816	3.61e-86	308.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,3JUPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
YYD3_k127_932166_0	1217720.ALOX01000034_gene336	8.901e-151	494.0	COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
YYD3_k127_932166_4	1121957.ATVL01000006_gene3095	1.648e-36	141.0	COG3296@1|root,COG3296@2|Bacteria,4NQGV@976|Bacteroidetes,47S3T@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870,SHOCT
YYD3_k127_932166_3	118173.KB235914_gene2153	3.343e-43	162.0	29699@1|root,2ZTJA@2|Bacteria	2|Bacteria	S	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
YYD3_k127_932166_5	644966.Tmar_0772	2.044e-30	122.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
YYD3_k127_93397_10	448385.sce6133	8.868e-08	62.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
YYD3_k127_93397_4	443144.GM21_0962	1.294e-69	247.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
YYD3_k127_93397_11	379066.GAU_2124	1.925e-07	59.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
YYD3_k127_93397_0	562970.Btus_2368	3.109e-142	460.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
YYD3_k127_93397_1	871968.DESME_10735	4.706e-140	462.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
YYD3_k127_93397_8	1291050.JAGE01000001_gene37	9.578e-37	141.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WITG@541000|Ruminococcaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
YYD3_k127_93397_2	1340493.JNIF01000003_gene4548	9.068e-118	392.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
YYD3_k127_93397_7	1267535.KB906767_gene4714	5.159e-37	147.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_93397_5	1158318.ATXC01000002_gene1588	6.886e-65	238.0	COG2265@1|root,COG2265@2|Bacteria,2G3V7@200783|Aquificae	200783|Aquificae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
YYD3_k127_93397_3	234267.Acid_6424	7.026e-80	295.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3Y3VQ@57723|Acidobacteria	57723|Acidobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
YYD3_k127_93397_6	344747.PM8797T_25126	1.022e-42	173.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
YYD3_k127_93397_9	234267.Acid_6308	1.737e-13	79.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
YYD3_k127_934088_3	314230.DSM3645_20387	1.613e-59	213.0	COG0235@1|root,COG0235@2|Bacteria,2J2P1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
YYD3_k127_934088_1	1173264.KI913949_gene37	5.253e-71	244.0	COG1791@1|root,COG1791@2|Bacteria,1G274@1117|Cyanobacteria	1117|Cyanobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
YYD3_k127_934088_4	1173264.KI913949_gene3008	1.331e-58	211.0	COG4229@1|root,COG4229@2|Bacteria,1G5UV@1117|Cyanobacteria,1HB8J@1150|Oscillatoriales	1117|Cyanobacteria	C	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
YYD3_k127_934088_8	1144275.COCOR_03122	1.871e-25	109.0	COG3832@1|root,COG5646@1|root,COG3832@2|Bacteria,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF1801
YYD3_k127_934088_6	744980.TRICHSKD4_0174	3.639e-32	133.0	COG5350@1|root,COG5350@2|Bacteria,1RDTX@1224|Proteobacteria,2U71X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein tyrosine phosphatase	MA20_42125	-	-	-	-	-	-	-	-	-	-	-	DSPc,Y_phosphatase
YYD3_k127_934088_5	1123399.AQVE01000001_gene736	2.045e-46	175.0	2DQHJ@1|root,336X1@2|Bacteria,1QYDU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_934088_0	204669.Acid345_1627	2.411e-215	677.0	COG0477@1|root,COG0477@2|Bacteria,3Y4JA@57723|Acidobacteria,2JJBX@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
YYD3_k127_934088_2	1340493.JNIF01000003_gene1745	2.763e-62	225.0	COG0037@1|root,COG0037@2|Bacteria	2|Bacteria	D	tRNA processing	ttcA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	6.3.4.19	ko:K04075,ko:K14058	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
YYD3_k127_934088_7	926566.Terro_0249	4.536e-29	123.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria,2JIQN@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
YYD3_k127_959961_2	502025.Hoch_2073	1.177e-76	266.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,42TE9@68525|delta/epsilon subdivisions,2WPGF@28221|Deltaproteobacteria,2YUH5@29|Myxococcales	28221|Deltaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
YYD3_k127_959961_3	278963.ATWD01000001_gene1740	4.424e-45	174.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria,2JKP9@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
YYD3_k127_959961_0	338966.Ppro_0096	2.52e-131	428.0	COG2512@1|root,COG3177@1|root,COG2512@2|Bacteria,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,42PWW@68525|delta/epsilon subdivisions,2WJM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
YYD3_k127_959961_1	1247726.MIM_c02340	4.138e-88	314.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
YYD3_k127_963982_2	1121423.JONT01000015_gene1289	1.858e-155	506.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
YYD3_k127_963982_4	1487923.DP73_14965	8.209e-122	403.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
YYD3_k127_963982_13	1211114.ALIP01000095_gene417	4.907e-19	90.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,1S9CV@1236|Gammaproteobacteria,1X80J@135614|Xanthomonadales	135614|Xanthomonadales	P	nitrite reductase	nasE	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
YYD3_k127_963982_11	251221.35210590	1.208e-58	214.0	COG0120@1|root,COG0120@2|Bacteria,1G2DW@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.rpiA	Rib_5-P_isom_A
YYD3_k127_963982_14	485916.Dtox_0827	3.481e-18	92.0	COG0560@1|root,COG0560@2|Bacteria,1VCP5@1239|Firmicutes,24AF0@186801|Clostridia	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
YYD3_k127_963982_7	639030.JHVA01000001_gene3891	3.665e-80	270.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
YYD3_k127_963982_12	234267.Acid_4787	7.138e-21	95.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria	57723|Acidobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
YYD3_k127_963982_8	1267534.KB906755_gene4317	1.249e-73	256.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria,2JI6M@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
YYD3_k127_963982_15	204669.Acid345_2756	4.74e-14	75.0	2C8EQ@1|root,3497J@2|Bacteria,3Y8QF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_963982_10	1487953.JMKF01000041_gene3137	6.079e-64	229.0	COG0583@1|root,COG0583@2|Bacteria,1G1R9@1117|Cyanobacteria,1H9NH@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD3_k127_963982_5	1210884.HG799468_gene13689	9.641e-97	326.0	COG0583@1|root,COG0583@2|Bacteria,2IYSZ@203682|Planctomycetes	203682|Planctomycetes	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
YYD3_k127_963982_6	234267.Acid_7942	9.907e-93	315.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,3Y6NP@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
YYD3_k127_963982_9	448385.sce6553	1.226e-68	239.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,2Z0M1@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase) cytochrome b subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
YYD3_k127_963982_0	234267.Acid_7402	0.0	1108.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria	57723|Acidobacteria	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
YYD3_k127_963982_3	234267.Acid_7403	3.81e-130	419.0	COG0479@1|root,COG0479@2|Bacteria,3Y3XR@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
YYD3_k127_963982_1	1340493.JNIF01000003_gene3309	1.165e-206	649.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria	57723|Acidobacteria	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
YYD3_k127_967210_0	1267535.KB906767_gene3131	7.081e-137	468.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria,2JI3C@204432|Acidobacteriia	204432|Acidobacteriia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
YYD3_k127_967210_1	1267535.KB906767_gene2358	5.151e-43	158.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
YYD3_k127_968278_2	794903.OPIT5_10075	2.066e-23	105.0	2ECF7@1|root,336DF@2|Bacteria,46XUM@74201|Verrucomicrobia,3K8A4@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
YYD3_k127_968278_1	1340493.JNIF01000003_gene4475	1.371e-34	138.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
YYD3_k127_968278_3	83406.HDN1F_17130	4.096e-22	100.0	COG2402@1|root,COG2402@2|Bacteria,1NCFK@1224|Proteobacteria,1SRQ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
YYD3_k127_968278_0	1396418.BATQ01000025_gene5256	3.171e-51	188.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
YYD3_k127_96937_3	234267.Acid_1806	4.621e-38	156.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IP@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
YYD3_k127_96937_4	1267534.KB906758_gene2504	2.101e-26	119.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria,2JJ3U@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
YYD3_k127_96937_0	1267533.KB906734_gene4269	4.118e-197	624.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	204432|Acidobacteriia	J	class II (D K	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
YYD3_k127_96937_1	1267533.KB906734_gene4271	2.741e-110	370.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
YYD3_k127_96937_2	1163408.UU9_03917	3.149e-87	302.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1X53W@135614|Xanthomonadales	135614|Xanthomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
YYD3_k127_977539_2	1267533.KB906736_gene1044	2.022e-22	106.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria,2JIP1@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
YYD3_k127_977539_0	1382359.JIAL01000001_gene2715	5.148e-134	433.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
YYD3_k127_977539_1	518766.Rmar_1413	4.665e-116	385.0	COG1166@1|root,COG1166@2|Bacteria,4PKX0@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
YYD3_k127_998378_3	401053.AciPR4_3000	3.094e-07	57.0	COG4772@1|root,COG4772@2|Bacteria,3Y47K@57723|Acidobacteria,2JMGP@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
YYD3_k127_998378_1	690850.Desaf_0015	1.714e-63	224.0	COG3860@1|root,COG3860@2|Bacteria,1RH83@1224|Proteobacteria,42ZD3@68525|delta/epsilon subdivisions,2WTXA@28221|Deltaproteobacteria,2MC2U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087
YYD3_k127_998378_2	329726.AM1_G0157	7.405e-45	166.0	COG0346@1|root,COG0346@2|Bacteria,1GG65@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
YYD3_k127_998378_0	1183438.GKIL_0560	5.923e-71	253.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
YYD3_k127_999732_2	204669.Acid345_2506	1.108e-19	95.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
YYD3_k127_999732_1	269799.Gmet_1275	3.82e-69	241.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
YYD3_k127_999732_0	240015.ACP_2453	4.607e-240	751.0	COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
## 3284 queries scanned
## Total time (seconds): 5.462484359741211
## Rate: 601.19 q/s