## Sat Oct 19 06:35:26 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/ZZS2_bin.10.fa -m mmseqs --itype genome -o ZZS2_bin.10 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/ZZS2_bin.10 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
ZZS2_k127_101293_4	948106.AWZT01000064_gene1760	5.299e-09	62.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4	ko:K00543,ko:K16130,ko:K18896,ko:K18897,ko:K21515	ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100	M00037	R03130,R04905,R10060,R10061	RC00003,RC00392,RC03038,RC03040	ko00000,ko00001,ko00002,ko01000,ko01008,ko03009	-	-	-	AMP-binding,Aminotran_1_2,AviRa,Condensation,Dimerisation2,Hen1_L,Methyltransf_12,Methyltransf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding
ZZS2_k127_101293_1	497964.CfE428DRAFT_5721	6.244e-179	591.0	COG2133@1|root,COG2133@2|Bacteria,46UAQ@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Laminin_G_3
ZZS2_k127_101293_2	1123242.JH636434_gene4936	1.063e-145	497.0	COG0421@1|root,COG0421@2|Bacteria,2J2TK@203682|Planctomycetes	203682|Planctomycetes	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
ZZS2_k127_101293_3	1219375.CM002139_gene3840	1.208e-25	119.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,1SETF@1236|Gammaproteobacteria,1X3XM@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS2_k127_101293_0	862908.BMS_1113	3.424e-244	772.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2MSS1@213481|Bdellovibrionales,2WINJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
ZZS2_k127_1019258_6	344747.PM8797T_11479	2.115e-10	70.0	COG5426@1|root,COG5426@2|Bacteria,2IY0Y@203682|Planctomycetes	203682|Planctomycetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_1019258_3	314230.DSM3645_26674	5.356e-58	212.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	2|Bacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_1019258_0	518766.Rmar_1285	1.559e-101	342.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1FJ1G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_1019258_5	452637.Oter_1389	1.206e-12	71.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_1019258_7	1036674.A28LD_1478	2.287e-08	69.0	COG4386@1|root,COG4386@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,Laminin_G_3,Rib
ZZS2_k127_1019258_1	1121957.ATVL01000013_gene61	1.432e-91	343.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
ZZS2_k127_1019258_8	1191523.MROS_1693	4.699e-07	64.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM60,CBM_4_9,CBM_6,Cellulase,F5_F8_type_C
ZZS2_k127_1019258_4	1121897.AUGO01000002_gene2177	7.763e-47	196.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_1019258_9	1396141.BATP01000026_gene1016	0.0004519	55.0	COG2931@1|root,COG5267@1|root,COG2931@2|Bacteria,COG5267@2|Bacteria,46YYY@74201|Verrucomicrobia,2ITXB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_1019258_2	526225.Gobs_2398	8.405e-83	293.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EVDD@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
ZZS2_k127_1032429_0	1396141.BATP01000043_gene1929	1.227e-104	387.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_1032429_1	1396141.BATP01000042_gene1927	1.017e-30	143.0	COG1520@1|root,COG4625@1|root,COG5295@1|root,COG1520@2|Bacteria,COG4625@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
ZZS2_k127_1035087_1	1341151.ASZU01000001_gene679	8.295e-241	768.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,27B9X@186824|Thermoactinomycetaceae	91061|Bacilli	F	AIR synthase related protein, C-terminal domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS2_k127_1035087_7	497964.CfE428DRAFT_2729	1.293e-70	250.0	COG1209@1|root,COG1209@2|Bacteria,46T9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS2_k127_1035087_4	1304880.JAGB01000003_gene993	2.47e-130	423.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia	186801|Clostridia	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
ZZS2_k127_1035087_2	497964.CfE428DRAFT_6291	9.406e-173	548.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
ZZS2_k127_1035087_11	497965.Cyan7822_2272	1.414e-20	101.0	COG0457@1|root,COG0457@2|Bacteria,1G5P9@1117|Cyanobacteria,3KHZX@43988|Cyanothece	1117|Cyanobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
ZZS2_k127_1035087_12	481448.Minf_0921	1.246e-16	83.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,37HAT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
ZZS2_k127_1035087_10	237368.SCABRO_02951	1.484e-24	115.0	COG0799@1|root,COG0799@2|Bacteria,2J0AM@203682|Planctomycetes	203682|Planctomycetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
ZZS2_k127_1035087_9	861299.J421_3567	4.985e-38	153.0	COG1057@1|root,COG1057@2|Bacteria,1ZTT1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS2_k127_1035087_0	497964.CfE428DRAFT_1084	2.695e-303	951.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
ZZS2_k127_1035087_6	118163.Ple7327_4575	3.843e-78	274.0	COG0079@1|root,COG0079@2|Bacteria,1FZV3@1117|Cyanobacteria,3VIDI@52604|Pleurocapsales	1117|Cyanobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
ZZS2_k127_1035087_3	240016.ABIZ01000001_gene2328	1.216e-131	432.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
ZZS2_k127_1035087_8	880072.Desac_1010	2.483e-57	214.0	COG1215@1|root,COG1215@2|Bacteria,1PC79@1224|Proteobacteria,42QYP@68525|delta/epsilon subdivisions,2X6HG@28221|Deltaproteobacteria,2MRKT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	hpnI	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
ZZS2_k127_1035087_5	673860.AciM339_1573	8.994e-87	299.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
ZZS2_k127_1057785_0	335659.S23_62680	0.0	1262.0	COG0001@1|root,COG1020@1|root,COG3321@1|root,COG0001@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3JQV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_25,PP-binding,Thioesterase,ketoacyl-synt
ZZS2_k127_1100417_3	497964.CfE428DRAFT_4579	7.045e-127	417.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ZZS2_k127_1100417_11	497964.CfE428DRAFT_4578	7.351e-34	135.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
ZZS2_k127_1100417_10	497964.CfE428DRAFT_4578	1.497e-41	159.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
ZZS2_k127_1100417_5	497964.CfE428DRAFT_3884	1.623e-86	289.0	COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
ZZS2_k127_1100417_7	1403819.BATR01000002_gene78	4.654e-65	228.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
ZZS2_k127_1100417_2	694431.DESACE_01260	5.844e-137	452.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2M6DK@213113|Desulfurellales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
ZZS2_k127_1100417_9	497964.CfE428DRAFT_0527	1.157e-46	172.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
ZZS2_k127_1100417_0	1156937.MFUM_1020055	2.658e-196	622.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia,37FYR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
ZZS2_k127_1100417_1	497964.CfE428DRAFT_0528	1.621e-174	566.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
ZZS2_k127_1100417_4	240016.ABIZ01000001_gene4776	5.656e-121	398.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
ZZS2_k127_1100417_8	452637.Oter_0478	4.96e-48	178.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
ZZS2_k127_1100417_13	1156937.MFUM_940009	5.656e-30	126.0	COG0839@1|root,COG0839@2|Bacteria,46T5P@74201|Verrucomicrobia,37GUV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
ZZS2_k127_1100417_12	583355.Caka_2578	4.425e-30	121.0	COG0713@1|root,COG0713@2|Bacteria,46YZN@74201|Verrucomicrobia,3K88N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
ZZS2_k127_1100417_6	481448.Minf_2213	1.317e-81	279.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,37GBS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
ZZS2_k127_1104346_4	215803.DB30_6069	2.865e-118	424.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,Pkinase,WD40
ZZS2_k127_1104346_14	1408433.JHXV01000007_gene2935	6.31e-28	131.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,1I3VW@117743|Flavobacteriia,2PBGT@246874|Cryomorphaceae	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
ZZS2_k127_1104346_12	179408.Osc7112_4244	5.012e-39	154.0	COG0784@1|root,COG0784@2|Bacteria,1G6K4@1117|Cyanobacteria,1HBJX@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_1104346_7	1173026.Glo7428_2080	1.202e-83	302.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1G1Z5@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HisKA
ZZS2_k127_1104346_15	1123242.JH636434_gene4662	3.922e-27	128.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_1104346_13	572477.Alvin_0700	2.256e-33	136.0	COG4251@1|root,COG4251@2|Bacteria,1N44A@1224|Proteobacteria,1SECK@1236|Gammaproteobacteria,1X14T@135613|Chromatiales	135613|Chromatiales	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
ZZS2_k127_1104346_11	316067.Geob_3569	2.258e-39	149.0	COG4251@1|root,COG4251@2|Bacteria,1N1KJ@1224|Proteobacteria,42W7E@68525|delta/epsilon subdivisions,2WSCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
ZZS2_k127_1104346_1	316067.Geob_3570	1.925e-229	731.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42P4F@68525|delta/epsilon subdivisions,2WJVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
ZZS2_k127_1104346_0	452637.Oter_4049	4.757e-239	750.0	COG0661@1|root,COG0661@2|Bacteria,46UJV@74201|Verrucomicrobia,3K7NS@414999|Opitutae	414999|Opitutae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
ZZS2_k127_1104346_6	240016.ABIZ01000001_gene2043	1.035e-102	348.0	COG0665@1|root,COG0665@2|Bacteria,46T7Y@74201|Verrucomicrobia,2IVJZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
ZZS2_k127_1104346_9	1128421.JAGA01000004_gene2519	2.07e-74	254.0	COG0693@1|root,COG0693@2|Bacteria,2NPFP@2323|unclassified Bacteria	2|Bacteria	S	DJ-1/PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
ZZS2_k127_1104346_5	234267.Acid_3006	5.767e-106	355.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_1104346_3	28072.Nos7524_0230	6.174e-174	556.0	COG2312@1|root,COG2312@2|Bacteria,1GK9Y@1117|Cyanobacteria,1HMEE@1161|Nostocales	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
ZZS2_k127_1104346_8	231434.JQJH01000016_gene1383	3.823e-75	260.0	COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3N9S9@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Erythromycin esterase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
ZZS2_k127_1104346_10	478741.JAFS01000001_gene2093	1.413e-66	237.0	COG0412@1|root,COG0412@2|Bacteria,46W4G@74201|Verrucomicrobia,37FWZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
ZZS2_k127_1104346_2	1163617.SCD_n00935	7.724e-216	696.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria	1224|Proteobacteria	NT	Chemotaxis	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HWE_HK,PAS,PAS_10,PAS_4
ZZS2_k127_1105803_2	497964.CfE428DRAFT_0088	6.808e-54	199.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_1105803_1	1173024.KI912148_gene2762	4.874e-71	256.0	COG0438@1|root,COG0438@2|Bacteria,1G1SZ@1117|Cyanobacteria,1JKQS@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS2_k127_1105803_0	497964.CfE428DRAFT_0087	4.107e-161	516.0	COG0451@1|root,COG0451@2|Bacteria,46US6@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
ZZS2_k127_1105803_3	1121428.DESHY_70084___1	3.416e-28	126.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1114147_0	234267.Acid_3680	0.0	1352.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
ZZS2_k127_1115727_0	1121957.ATVL01000013_gene61	2.638e-139	459.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
ZZS2_k127_1115727_1	1379698.RBG1_1C00001G0175	2.699e-120	415.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,2NRE7@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02022,ko:K16922,ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002,ko02000	3.A.1.112,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,PqqD
ZZS2_k127_1115727_4	247490.KSU1_A0074	2.373e-34	138.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS2_k127_1115727_3	1396141.BATP01000054_gene2918	1.649e-66	248.0	COG2159@1|root,COG2159@2|Bacteria,46XFJ@74201|Verrucomicrobia,2IVS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_1115727_5	794903.OPIT5_17215	1.467e-11	75.0	2EGE2@1|root,33A5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1115727_2	639030.JHVA01000001_gene2709	2.994e-97	326.0	28KUD@1|root,2ZAB6@2|Bacteria	2|Bacteria	-	-	yndJ	-	-	-	-	-	-	-	-	-	-	-	YndJ
ZZS2_k127_1115727_6	324602.Caur_3080	5.967e-05	55.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Asp_protease_2,FG-GAP_2,HemolysinCabind,Lectin_C,VWA,VWA_2
ZZS2_k127_1127163_16	497964.CfE428DRAFT_2334	2.936e-57	204.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
ZZS2_k127_1127163_19	452637.Oter_1403	4.46e-41	154.0	COG3123@1|root,COG3123@2|Bacteria,46VVG@74201|Verrucomicrobia,3K88M@414999|Opitutae	414999|Opitutae	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
ZZS2_k127_1127163_8	497964.CfE428DRAFT_1043	3.558e-130	424.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
ZZS2_k127_1127163_14	243090.RB9120	2.459e-77	293.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3250@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3250@2|Bacteria,2IYJR@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
ZZS2_k127_1127163_9	530564.Psta_2908	1.648e-121	402.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
ZZS2_k127_1127163_24	357808.RoseRS_1016	2.6e-15	92.0	COG1520@1|root,COG1520@2|Bacteria,2GBKY@200795|Chloroflexi,375ZC@32061|Chloroflexia	32061|Chloroflexia	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_1127163_17	1396141.BATP01000034_gene4198	3.569e-53	216.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_1127163_26	1121405.dsmv_0737	2.56e-09	72.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
ZZS2_k127_1127163_6	497964.CfE428DRAFT_6119	1.346e-182	577.0	COG0667@1|root,COG0667@2|Bacteria,46TN3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS2_k127_1127163_12	497964.CfE428DRAFT_6191	8.251e-109	365.0	28JQV@1|root,2Z7R2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1127163_13	1166018.FAES_3050	7.018e-91	319.0	2DBA6@1|root,2Z814@2|Bacteria,4NFI6@976|Bacteroidetes,47MPW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1127163_5	382464.ABSI01000021_gene382	2.362e-189	603.0	COG1524@1|root,COG1524@2|Bacteria,46UZ5@74201|Verrucomicrobia,2ITHB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS2_k127_1127163_11	382464.ABSI01000021_gene383	9.789e-121	400.0	COG0337@1|root,COG0337@2|Bacteria,46UQ7@74201|Verrucomicrobia,2ITKA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
ZZS2_k127_1127163_2	314230.DSM3645_01876	2.479e-234	754.0	COG0308@1|root,COG0308@2|Bacteria,2IY5F@203682|Planctomycetes	203682|Planctomycetes	M	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
ZZS2_k127_1127163_1	497964.CfE428DRAFT_4984	3.253e-237	761.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
ZZS2_k127_1127163_20	1156937.MFUM_1010067	1.814e-38	153.0	COG0741@1|root,COG0741@2|Bacteria,46W79@74201|Verrucomicrobia,37GKP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
ZZS2_k127_1127163_21	1403819.BATR01000177_gene5954	1.93e-37	151.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,2IUKE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
ZZS2_k127_1127163_15	497964.CfE428DRAFT_4571	6.409e-70	242.0	COG0632@1|root,COG0632@2|Bacteria,46SZF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
ZZS2_k127_1127163_22	1123070.KB899248_gene14	1.566e-30	128.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
ZZS2_k127_1127163_18	497964.CfE428DRAFT_2623	3.695e-42	161.0	COG0424@1|root,COG0424@2|Bacteria,46VR6@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Maf-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Maf
ZZS2_k127_1127163_23	1123508.JH636443_gene4799	5.448e-30	126.0	COG4293@1|root,COG4293@2|Bacteria,2J0GT@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
ZZS2_k127_1127163_25	1123267.JONN01000001_gene1815	1.237e-10	69.0	COG1426@1|root,COG1426@2|Bacteria,1ND8D@1224|Proteobacteria,2UB49@28211|Alphaproteobacteria,2K57P@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
ZZS2_k127_1127163_27	1265505.ATUG01000003_gene110	3.616e-09	68.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2MJIP@213118|Desulfobacterales	28221|Deltaproteobacteria	O	peptidyl-prolyl cis-trans isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
ZZS2_k127_1127163_10	497964.CfE428DRAFT_5147	1.659e-121	410.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS2_k127_1127163_4	497964.CfE428DRAFT_5146	7.257e-190	606.0	COG1541@1|root,COG1541@2|Bacteria,46UTU@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
ZZS2_k127_1127163_7	497964.CfE428DRAFT_5145	3.777e-169	543.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_1127163_3	497964.CfE428DRAFT_5144	1.498e-231	753.0	COG1250@1|root,COG1250@2|Bacteria,46U5Q@74201|Verrucomicrobia	74201|Verrucomicrobia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
ZZS2_k127_1127163_0	497964.CfE428DRAFT_5143	1.67e-257	808.0	COG1960@1|root,COG1960@2|Bacteria,46TJY@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_1128765_0	696281.Desru_3104	0.0001841	53.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	fimU	-	-	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
ZZS2_k127_1128765_1	1210884.HG799462_gene9274	0.0003753	52.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_1154724_8	344747.PM8797T_26730	9.552e-55	196.0	COG4102@1|root,COG4102@2|Bacteria,2IY2D@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1154724_0	344747.PM8797T_26725	1.819e-305	968.0	COG2010@1|root,COG2010@2|Bacteria,2IYM5@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_1154724_4	314230.DSM3645_28727	1.703e-93	326.0	COG0613@1|root,COG0613@2|Bacteria,2IZFJ@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1154724_2	240016.ABIZ01000001_gene5895	3.2e-126	414.0	COG2133@1|root,COG2133@2|Bacteria,46ZKI@74201|Verrucomicrobia,2IVI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_1154724_13	1123309.AQYB01000030_gene1849	1.092e-26	119.0	COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
ZZS2_k127_1154724_15	411476.BACOVA_05382	3.724e-25	114.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,2FRYM@200643|Bacteroidia,4AQNY@815|Bacteroidaceae	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
ZZS2_k127_1154724_19	28583.AMAG_01224T0	6.283e-06	60.0	KOG0283@1|root,KOG0283@2759|Eukaryota,38EG2@33154|Opisthokonta,3NWE2@4751|Fungi	4751|Fungi	J	Wd repeat protein	-	GO:0005575,GO:0032991	-	ko:K20241	-	-	-	-	ko00000,ko04131	-	-	-	WD40
ZZS2_k127_1154724_5	382464.ABSI01000011_gene2968	1.913e-67	261.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1154724_1	240016.ABIZ01000001_gene824	4.768e-202	648.0	COG0859@1|root,COG0859@2|Bacteria,46TJT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Mannosyl_trans3
ZZS2_k127_1154724_7	330214.NIDE0621	2.53e-57	224.0	29B5A@1|root,2Z9JA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1154724_16	1123242.JH636435_gene783	3.005e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_1154724_6	1341151.ASZU01000004_gene51	2.854e-63	248.0	COG3023@1|root,COG3023@2|Bacteria,1TR62@1239|Firmicutes,4HGHR@91061|Bacilli,27B79@186824|Thermoactinomycetaceae	91061|Bacilli	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,SLT
ZZS2_k127_1154724_10	1170562.Cal6303_0175	1.999e-39	170.0	COG2133@1|root,COG2931@1|root,COG3299@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3299@2|Bacteria,1G2CB@1117|Cyanobacteria,1HRM4@1161|Nostocales	1117|Cyanobacteria	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,PA14
ZZS2_k127_1154724_11	1403819.BATR01000162_gene5376	2.592e-38	170.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	PATR
ZZS2_k127_1154724_18	7668.SPU_002355-tr	9.848e-08	68.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38VUM@33154|Opisthokonta,3BYZ5@33208|Metazoa,3DFE0@33213|Bilateria	33208|Metazoa	T	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
ZZS2_k127_1154724_12	383372.Rcas_2969	3.217e-35	160.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1154724_9	1121920.AUAU01000009_gene1881	4.053e-47	199.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_1154724_17	309800.C498_02055	1.107e-13	88.0	arCOG05978@1|root,arCOG05978@2157|Archaea,2XU7Y@28890|Euryarchaeota,23SST@183963|Halobacteria	183963|Halobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1154724_14	1396141.BATP01000003_gene4864	2.42e-25	127.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
ZZS2_k127_1154724_20	529818.AMSG_00600T0	0.0004805	56.0	KOG1218@1|root,KOG1225@1|root,KOG3594@1|root,KOG3597@1|root,KOG1218@2759|Eukaryota,KOG1225@2759|Eukaryota,KOG3597@2759|Eukaryota,KOG4289@2759|Eukaryota	2759|Eukaryota	O	homophilic cell adhesion via plasma membrane adhesion molecules	CSPG4	GO:0000187,GO:0000323,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005775,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0005912,GO:0005924,GO:0005927,GO:0006022,GO:0006023,GO:0006024,GO:0006026,GO:0006027,GO:0006029,GO:0006082,GO:0006790,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007186,GO:0007275,GO:0007399,GO:0007517,GO:0008150,GO:0008152,GO:0008283,GO:0008347,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009653,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010721,GO:0010927,GO:0010975,GO:0010977,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016053,GO:0016203,GO:0016322,GO:0016477,GO:0017144,GO:0019220,GO:0019222,GO:0019538,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030054,GO:0030055,GO:0030154,GO:0030166,GO:0030182,GO:0030203,GO:0030204,GO:0030205,GO:0030206,GO:0030207,GO:0030208,GO:0030239,GO:0031032,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031346,GO:0031399,GO:0031401,GO:0031674,GO:0031974,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032787,GO:0032989,GO:0033674,GO:0034645,GO:0035556,GO:0040011,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042551,GO:0042692,GO:0042995,GO:0043034,GO:0043085,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043436,GO:0043549,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044272,GO:0044273,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044464,GO:0044877,GO:0045214,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045859,GO:0045860,GO:0045937,GO:0046394,GO:0048468,GO:0048469,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050650,GO:0050651,GO:0050654,GO:0050655,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051286,GO:0051338,GO:0051347,GO:0051489,GO:0051491,GO:0051674,GO:0051716,GO:0051960,GO:0051961,GO:0055001,GO:0055002,GO:0060255,GO:0060284,GO:0060491,GO:0060538,GO:0061061,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070925,GO:0071695,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072330,GO:0080090,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0120032,GO:0120034,GO:0120035,GO:1901135,GO:1901136,GO:1901137,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902531,GO:1902533,GO:1903510,GO:2000026	-	ko:K02599,ko:K08115,ko:K16507,ko:K16669,ko:K19013	ko01522,ko04320,ko04330,ko04391,ko04392,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04391,map04392,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002,ko00535,ko00536,ko04516	-	-	-	Cadherin_3,EB,Laminin_G_2
ZZS2_k127_1154724_3	1403819.BATR01000114_gene3902	3.012e-116	381.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1163180_4	886293.Sinac_2603	5.472e-52	188.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS2_k127_1163180_1	497964.CfE428DRAFT_5490	2.302e-118	391.0	COG0524@1|root,COG0524@2|Bacteria,46SCP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS2_k127_1163180_0	1089544.KB912942_gene2379	2.771e-158	511.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4E5YA@85010|Pseudonocardiales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
ZZS2_k127_1163180_3	497964.CfE428DRAFT_2716	3.151e-96	328.0	COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
ZZS2_k127_1163180_2	497964.CfE428DRAFT_2715	1.422e-114	387.0	COG0793@1|root,COG0793@2|Bacteria,46SM7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
ZZS2_k127_1176852_10	497964.CfE428DRAFT_0064	2.581e-55	201.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_1176852_8	497964.CfE428DRAFT_0066	8.662e-79	298.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_1176852_13	97096.XP_007798630.1	2.003e-05	59.0	KOG0278@1|root,KOG0278@2759|Eukaryota,38BC1@33154|Opisthokonta,3NZ3I@4751|Fungi,3QK73@4890|Ascomycota,215I1@147550|Sordariomycetes	4751|Fungi	I	serine-threonine kinase receptor-associated protein	-	-	-	ko:K13137	ko03013,map03013	M00426	-	-	ko00000,ko00001,ko00002,ko03041	-	-	-	WD40
ZZS2_k127_1176852_12	269799.Gmet_0659	9.571e-09	67.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria,43TJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_1176852_6	497964.CfE428DRAFT_4948	3.173e-115	390.0	COG0438@1|root,COG0438@2|Bacteria,46UG2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_1176852_3	661478.OP10G_1529	1.705e-151	499.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS2_k127_1176852_7	316067.Geob_2986	1.808e-96	359.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
ZZS2_k127_1176852_14	1396141.BATP01000040_gene2087	2.402e-05	59.0	COG2273@1|root,COG3209@1|root,COG4625@1|root,COG2273@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF5011,He_PIG,Laminin_G_3,PATR,Phospholip_A2_3,RHS_repeat
ZZS2_k127_1176852_9	1121468.AUBR01000015_gene2251	1.843e-58	211.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,42I9V@68295|Thermoanaerobacterales	186801|Clostridia	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
ZZS2_k127_1176852_5	1521187.JPIM01000020_gene212	1.204e-127	422.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
ZZS2_k127_1176852_11	497964.CfE428DRAFT_3323	4.221e-24	108.0	COG2165@1|root,COG2165@2|Bacteria,46T3S@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_1176852_4	1267534.KB906754_gene3770	3.135e-142	467.0	COG1007@1|root,COG1007@2|Bacteria,3Y73U@57723|Acidobacteria,2JMM8@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS2_k127_1176852_1	1267534.KB906754_gene3771	1.355e-214	678.0	COG1008@1|root,COG1008@2|Bacteria,3Y6FA@57723|Acidobacteria,2JM6J@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS2_k127_1176852_2	1267534.KB906754_gene3772	6.007e-193	616.0	COG1008@1|root,COG1008@2|Bacteria,3Y6ZF@57723|Acidobacteria,2JMB1@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS2_k127_1176852_0	1267534.KB906754_gene3773	3.916e-260	825.0	COG1009@1|root,COG1009@2|Bacteria,3Y76V@57723|Acidobacteria,2JMJJ@204432|Acidobacteriia	204432|Acidobacteriia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
ZZS2_k127_1204548_2	1396141.BATP01000006_gene5477	1.867e-256	815.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_1204548_9	1116375.VEJY3_08135	1.29e-10	76.0	COG3291@1|root,COG3291@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1204548_4	865937.Gilli_0558	1.13e-156	549.0	COG1520@1|root,COG2304@1|root,COG3391@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG3391@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2P5SV@244698|Gillisia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
ZZS2_k127_1204548_7	941449.dsx2_2880	4.003e-68	266.0	2CDBG@1|root,343FF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1204548_8	498848.TaqDRAFT_4878	7.559e-44	176.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1204548_3	886293.Sinac_6992	7e-181	575.0	COG4806@1|root,COG4806@2|Bacteria,2IXTQ@203682|Planctomycetes	203682|Planctomycetes	G	L-rhamnose isomerase	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
ZZS2_k127_1204548_5	525904.Tter_2007	1.88e-135	457.0	2CB42@1|root,2Z7Y3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1204548_1	497964.CfE428DRAFT_5970	1.021e-260	818.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia	74201|Verrucomicrobia	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_1204548_0	497964.CfE428DRAFT_2396	1.233e-296	921.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
ZZS2_k127_1204548_10	28072.Nos7524_4621	6.428e-08	66.0	COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales	1117|Cyanobacteria	MU	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,He_PIG,RHS_repeat
ZZS2_k127_1204548_6	1278073.MYSTI_07731	2.335e-101	354.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS2_k127_1211932_0	497964.CfE428DRAFT_0194	0.0	1647.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
ZZS2_k127_1211932_8	382464.ABSI01000010_gene3251	9.958e-10	67.0	COG0526@1|root,COG3210@1|root,COG0526@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Omp28
ZZS2_k127_1211932_6	382464.ABSI01000012_gene2101	4.555e-30	138.0	COG0526@1|root,COG4935@1|root,COG0526@2|Bacteria,COG4935@2|Bacteria,46UYI@74201|Verrucomicrobia,2IWE7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_1211932_9	1396418.BATQ01000018_gene4130	5.258e-05	49.0	COG1714@1|root,COG1714@2|Bacteria,46T8Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
ZZS2_k127_1211932_1	452637.Oter_3359	2.848e-312	980.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
ZZS2_k127_1211932_4	478741.JAFS01000001_gene1701	6.308e-114	381.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,37FWS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
ZZS2_k127_1211932_2	1123073.KB899241_gene3268	4.401e-252	785.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
ZZS2_k127_1211932_3	1403819.BATR01000185_gene6420	3.685e-194	611.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,2ITRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
ZZS2_k127_1211932_5	497964.CfE428DRAFT_2087	3.066e-106	353.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia	74201|Verrucomicrobia	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
ZZS2_k127_1211932_7	452637.Oter_0986	1.476e-11	76.0	2AXAG@1|root,31P9J@2|Bacteria,46XVM@74201|Verrucomicrobia,3K8EC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1248463_0	452637.Oter_0494	5.863e-56	205.0	COG0564@1|root,COG0564@2|Bacteria,46ZAW@74201|Verrucomicrobia,3K7AJ@414999|Opitutae	414999|Opitutae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
ZZS2_k127_1248463_1	1122236.KB905141_gene901	7.178e-05	55.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,2KM3X@206350|Nitrosomonadales	206350|Nitrosomonadales	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
ZZS2_k127_1250418_1	1123508.JH636439_gene754	5.542e-43	163.0	COG1520@1|root,COG1520@2|Bacteria,2IYJ1@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_1250418_0	1396141.BATP01000003_gene4934	1.387e-97	348.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_1250418_2	497964.CfE428DRAFT_4578	4.814e-27	114.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
ZZS2_k127_1250773_19	1169144.KB910961_gene4059	1.208e-08	60.0	COG0846@1|root,COG0846@2|Bacteria,1V34D@1239|Firmicutes,4HPF1@91061|Bacilli,1ZMBE@1386|Bacillus	91061|Bacilli	K	Domain of unknown function (DUF4020)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4020,SIR2_2
ZZS2_k127_1250773_8	1449058.JQKT01000001_gene284	1.095e-34	136.0	COG3591@1|root,COG3591@2|Bacteria,2IN6Y@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
ZZS2_k127_1250773_2	449447.MAE_12430	1.674e-69	272.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
ZZS2_k127_1250773_13	1313172.YM304_00530	2.282e-18	103.0	COG0584@1|root,COG1361@1|root,COG3291@1|root,COG3897@1|root,COG5184@1|root,COG0584@2|Bacteria,COG1361@2|Bacteria,COG3291@2|Bacteria,COG3897@2|Bacteria,COG5184@2|Bacteria,2GTZZ@201174|Actinobacteria	201174|Actinobacteria	CDZ	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1250773_11	1300345.LF41_48	4.717e-24	121.0	COG0028@1|root,COG1520@1|root,COG3391@1|root,COG3693@1|root,COG0028@2|Bacteria,COG1520@2|Bacteria,COG3391@2|Bacteria,COG3693@2|Bacteria,1QYUP@1224|Proteobacteria	1224|Proteobacteria	EH	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
ZZS2_k127_1250773_0	886293.Sinac_6489	4.776e-118	418.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_1250773_3	497964.CfE428DRAFT_4864	4.446e-66	233.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1250773_16	156889.Mmc1_2864	1.471e-11	65.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
ZZS2_k127_1250773_17	1396418.BATQ01000025_gene5255	2.995e-11	70.0	COG1073@1|root,COG1073@2|Bacteria,46TMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1250773_12	1396418.BATQ01000025_gene5255	3.402e-22	96.0	COG1073@1|root,COG1073@2|Bacteria,46TMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1250773_10	497964.CfE428DRAFT_6631	9.036e-26	115.0	COG3386@1|root,COG4733@1|root,COG3386@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K14274,ko:K20276	ko00040,ko02024,map00040,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	DUF5122,He_PIG,Laminin_G_3,SBBP,SGL,SLH
ZZS2_k127_1250773_6	1396141.BATP01000022_gene383	8.39e-40	166.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
ZZS2_k127_1250773_9	1121121.KB894291_gene1353	8.894e-34	148.0	COG0346@1|root,COG0346@2|Bacteria,1V48E@1239|Firmicutes,4HHUT@91061|Bacilli,26XMC@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	yurT	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_1250773_5	1144275.COCOR_01398	4.897e-43	176.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,43827@68525|delta/epsilon subdivisions,2X3CD@28221|Deltaproteobacteria,2YVE1@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_1250773_14	1303518.CCALI_00913	2.496e-14	83.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
ZZS2_k127_1250773_4	1443665.JACA01000012_gene1280	9.135e-47	190.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
ZZS2_k127_1250773_1	886293.Sinac_3618	2.919e-99	362.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_1250773_7	497964.CfE428DRAFT_4864	9.342e-35	137.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1271366_5	794903.OPIT5_07360	4.763e-39	146.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS2_k127_1271366_0	452637.Oter_1547	0.0	1161.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,3K82Q@414999|Opitutae	414999|Opitutae	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
ZZS2_k127_1271366_1	861299.J421_1753	3.53e-291	938.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_1271366_2	1396141.BATP01000023_gene713	2.845e-274	860.0	COG3408@1|root,COG4412@1|root,COG3408@2|Bacteria,COG4412@2|Bacteria,46XDF@74201|Verrucomicrobia,2IVJ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1271366_4	240016.ABIZ01000001_gene3134	4.076e-64	235.0	COG0628@1|root,COG0628@2|Bacteria,46VTV@74201|Verrucomicrobia,2ITP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS2_k127_1271366_3	344747.PM8797T_06842	1.384e-85	292.0	COG0345@1|root,COG0345@2|Bacteria,2IY5U@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
ZZS2_k127_1284150_1	886293.Sinac_4910	4.867e-178	566.0	COG1082@1|root,COG1082@2|Bacteria,2J24A@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
ZZS2_k127_1284150_2	1116369.KB890025_gene5227	0.0009593	44.0	COG4311@1|root,COG4311@2|Bacteria,1N8ED@1224|Proteobacteria,2UFIN@28211|Alphaproteobacteria,43M8A@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Sarcosine oxidase, delta subunit	soxD	-	1.5.3.1,1.5.99.5	ko:K00304,ko:K22085	ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120	-	R00609,R00610	RC00060,RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
ZZS2_k127_1284150_0	1120963.KB894499_gene422	8.586e-219	756.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_1288026_3	575540.Isop_1075	1.274e-09	60.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_1288026_2	583355.Caka_2501	1.076e-28	120.0	COG2166@1|root,COG2166@2|Bacteria,46W04@74201|Verrucomicrobia,3K88I@414999|Opitutae	414999|Opitutae	S	Fe-S metabolism	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
ZZS2_k127_1288026_0	497964.CfE428DRAFT_1462	2.307e-83	285.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ZZS2_k127_1288026_1	497964.CfE428DRAFT_1464	2.056e-77	267.0	COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
ZZS2_k127_12964_3	382464.ABSI01000010_gene3258	1.007e-89	336.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_12964_8	1396141.BATP01000036_gene3845	1.771e-23	119.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,PQQ_2
ZZS2_k127_12964_11	1408473.JHXO01000004_gene27	0.0001324	56.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
ZZS2_k127_12964_7	382464.ABSI01000011_gene3180	2.171e-33	148.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_12964_9	583355.Caka_0406	8.723e-12	76.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_16,Glyco_hydro_43,Glyco_hydro_67N,Thaumatin,Trypsin,UnbV_ASPIC,VCBS
ZZS2_k127_12964_0	243090.RB5313	1.678e-245	778.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
ZZS2_k127_12964_4	1123242.JH636435_gene769	5.095e-66	238.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
ZZS2_k127_12964_10	497964.CfE428DRAFT_5429	2.66e-09	66.0	COG1520@1|root,COG1520@2|Bacteria,46TI7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_12964_2	478741.JAFS01000002_gene995	4.614e-122	398.0	COG1432@1|root,COG1432@2|Bacteria,46SBH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
ZZS2_k127_12964_6	472759.Nhal_0251	2.119e-40	164.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
ZZS2_k127_12964_1	543632.JOJL01000013_gene9332	8.41e-135	445.0	COG0627@1|root,COG0627@2|Bacteria,2I3VM@201174|Actinobacteria	201174|Actinobacteria	S	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
ZZS2_k127_1310697_2	1142394.PSMK_11490	8.651e-06	58.0	COG2165@1|root,COG2165@2|Bacteria,2IXC8@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_1310697_0	1370121.AUWS01000016_gene7004	5.328e-79	278.0	COG5586@1|root,COG5586@2|Bacteria,2GX58@201174|Actinobacteria,237WQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
ZZS2_k127_1310697_1	485913.Krac_2885	6.747e-20	101.0	COG2355@1|root,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_1319515_12	1396141.BATP01000060_gene4727	1.805e-40	162.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_1319515_15	1121920.AUAU01000009_gene1881	3.517e-28	134.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_1319515_5	1122165.AUHS01000047_gene3184	2.569e-125	451.0	COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
ZZS2_k127_1319515_14	696747.NIES39_C00730	6.456e-32	133.0	COG0681@1|root,COG0681@2|Bacteria,1G54H@1117|Cyanobacteria,1H8FZ@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
ZZS2_k127_1319515_16	595460.RRSWK_06974	1.029e-24	123.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_1319515_21	1410628.JNKS01000016_gene69	0.0007582	54.0	COG5337@1|root,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,27J6M@186928|unclassified Lachnospiraceae	186801|Clostridia	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
ZZS2_k127_1319515_8	382464.ABSI01000005_gene1189	1.832e-78	301.0	COG2312@1|root,COG5337@1|root,COG2312@2|Bacteria,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_1319515_4	944479.JQLX01000013_gene1342	7.56e-151	493.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2M6UY@213113|Desulfurellales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
ZZS2_k127_1319515_7	1449126.JQKL01000018_gene3257	1.098e-91	314.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,268GC@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
ZZS2_k127_1319515_11	1120958.AULD01000006_gene519	7.526e-46	178.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4FNXD@85023|Microbacteriaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
ZZS2_k127_1319515_0	886293.Sinac_5109	6.71e-273	865.0	COG2010@1|root,COG2010@2|Bacteria,2IXIG@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_1319515_1	886293.Sinac_5110	9.879e-209	659.0	COG3119@1|root,COG3119@2|Bacteria,2IXSN@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1319515_18	13689.BV96_00138	6.484e-19	95.0	COG2227@1|root,COG2227@2|Bacteria,1QUR5@1224|Proteobacteria,2TW4B@28211|Alphaproteobacteria,2KEAC@204457|Sphingomonadales	204457|Sphingomonadales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_1319515_6	240016.ABIZ01000001_gene4766	9.554e-111	366.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ZZS2_k127_1319515_20	1341155.FSS13T_18290	1.364e-14	85.0	COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,1I20E@117743|Flavobacteriia,2NW5M@237|Flavobacterium	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
ZZS2_k127_1319515_17	309807.SRU_0411	6.224e-24	113.0	COG2259@1|root,COG2259@2|Bacteria,4PK4D@976|Bacteroidetes,1FK9G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
ZZS2_k127_1319515_19	378806.STAUR_7979	1.402e-16	90.0	2E2RY@1|root,32XUA@2|Bacteria,1N9C1@1224|Proteobacteria,42XP0@68525|delta/epsilon subdivisions,2WT7T@28221|Deltaproteobacteria,2YVJE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
ZZS2_k127_1319515_10	1122134.KB893650_gene1620	2.666e-46	178.0	COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria,1S7BW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_1319515_9	379066.GAU_3344	9.736e-78	267.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,NTP_transf_2
ZZS2_k127_1319515_13	324057.Pjdr2_0886	9.546e-36	148.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
ZZS2_k127_1319515_3	344747.PM8797T_06380	1.32e-161	524.0	COG0388@1|root,COG0388@2|Bacteria,2IXSE@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
ZZS2_k127_1319515_2	344747.PM8797T_26730	6.247e-183	576.0	COG4102@1|root,COG4102@2|Bacteria,2IY2D@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1340213_2	714943.Mucpa_6538	1.017e-51	185.0	COG1850@1|root,COG1850@2|Bacteria,4NFRC@976|Bacteroidetes,1IQT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the RuBisCO large chain family	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
ZZS2_k127_1340213_0	714943.Mucpa_6537	6.812e-119	397.0	COG3395@1|root,COG3395@2|Bacteria,4NFF9@976|Bacteroidetes,1IR7P@117747|Sphingobacteriia	976|Bacteroidetes	S	Type III effector Hrp-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
ZZS2_k127_1340213_1	1122917.KB899667_gene3587	2.506e-89	307.0	COG2085@1|root,COG2085@2|Bacteria,1TWYH@1239|Firmicutes	1239|Firmicutes	S	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	IlvN,PGDH_C
ZZS2_k127_1344850_14	595460.RRSWK_04758	2.661e-33	136.0	2E5WH@1|root,32RS6@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS2_k127_1344850_2	497964.CfE428DRAFT_3523	1.771e-251	783.0	COG4102@1|root,COG4102@2|Bacteria,46UJZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1344850_0	1396418.BATQ01000181_gene847	0.0	1035.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_1344850_1	861299.J421_1753	1.737e-269	880.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_1344850_4	635013.TherJR_2099	1.367e-160	528.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
ZZS2_k127_1344850_6	497964.CfE428DRAFT_0621	8.075e-117	391.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS2_k127_1344850_13	56780.SYN_00753	5.323e-34	134.0	2CIE9@1|root,32S7U@2|Bacteria,1P112@1224|Proteobacteria,431TX@68525|delta/epsilon subdivisions,2WWP3@28221|Deltaproteobacteria,2MS3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
ZZS2_k127_1344850_3	269799.Gmet_1416	8.846e-187	611.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
ZZS2_k127_1344850_16	1255043.TVNIR_1015	3.814e-12	77.0	2CD0K@1|root,32V6E@2|Bacteria,1N4B2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1344850_7	886293.Sinac_7126	7.178e-109	364.0	COG1524@1|root,COG1524@2|Bacteria,2IYCV@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS2_k127_1344850_5	452637.Oter_2356	4.422e-117	387.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,3K7U5@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
ZZS2_k127_1344850_12	794903.OPIT5_02620	5.842e-38	145.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
ZZS2_k127_1344850_15	1123070.KB899264_gene1796	2.818e-12	69.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
ZZS2_k127_1344850_8	215803.DB30_6334	4.034e-91	333.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2Z3F9@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
ZZS2_k127_1344850_10	1396418.BATQ01000049_gene411	2.819e-75	269.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46U96@74201|Verrucomicrobia,2ITU0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
ZZS2_k127_1344850_11	1502770.JQMG01000001_gene901	2.507e-59	208.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WHYU@28216|Betaproteobacteria,2KNBE@206350|Nitrosomonadales	206350|Nitrosomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_1344850_9	395961.Cyan7425_3017	5.133e-89	321.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,3KH7P@43988|Cyanothece	1117|Cyanobacteria	T	Multi-sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4
ZZS2_k127_1359153_8	378806.STAUR_8257	3.963e-06	61.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Kelch_4,VCBS
ZZS2_k127_1359153_0	497964.CfE428DRAFT_5974	0.0	1969.0	COG0419@1|root,COG1112@1|root,COG3831@1|root,COG0419@2|Bacteria,COG1112@2|Bacteria,COG3831@2|Bacteria	2|Bacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011,Tubulin_2,WGR
ZZS2_k127_1359153_3	314230.DSM3645_14690	6.109e-112	374.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_1359153_4	1396141.BATP01000043_gene1929	3.943e-74	286.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_1359153_6	1242864.D187_004781	2.039e-28	134.0	COG2730@1|root,COG2730@2|Bacteria,1R544@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
ZZS2_k127_1359153_1	1210884.HG799468_gene13560	1.973e-278	886.0	COG2010@1|root,COG2010@2|Bacteria,2IYFF@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_1359153_2	1210884.HG799468_gene13561	1.077e-218	686.0	COG3119@1|root,COG3119@2|Bacteria,2IWZ2@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1359153_5	395493.BegalDRAFT_2020	1.498e-68	242.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,460YK@72273|Thiotrichales	72273|Thiotrichales	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_1359153_7	351348.Maqu_2299	5.492e-09	60.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Big_2,CBM9_1,CW_binding_1,Glyco_hydro_43,LRR_5,Laminin_G_3,Peptidase_S9,SLH,WG_beta_rep,fn3
ZZS2_k127_1370636_11	478741.JAFS01000002_gene142	1.253e-10	68.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
ZZS2_k127_1370636_9	478741.JAFS01000002_gene140	2.161e-26	119.0	COG1792@1|root,COG1792@2|Bacteria,46T2J@74201|Verrucomicrobia,37FYP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
ZZS2_k127_1370636_2	1123070.KB899252_gene961	3.127e-160	510.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ZZS2_k127_1370636_0	497964.CfE428DRAFT_4368	7.5e-218	687.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,PQQ_2,PQQ_3
ZZS2_k127_1370636_3	1123248.KB893314_gene3333	4.052e-131	427.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS2_k127_1370636_4	452637.Oter_0312	4.043e-126	455.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
ZZS2_k127_1370636_8	448385.sce0987	3.33e-37	154.0	COG1520@1|root,COG4932@1|root,COG5624@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,COG5624@2|Bacteria,1QUEG@1224|Proteobacteria,42YJZ@68525|delta/epsilon subdivisions,2WWPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KM	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B,TGFb_propeptide
ZZS2_k127_1370636_1	240016.ABIZ01000001_gene4459	2.88e-166	543.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,46SJI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,SIS_2
ZZS2_k127_1370636_12	1209072.ALBT01000067_gene139	3.59e-06	57.0	28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,1FGGM@10|Cellvibrio	1236|Gammaproteobacteria	S	Yip1 domain	yohC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1282
ZZS2_k127_1370636_10	880073.Calab_0674	2.831e-13	83.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
ZZS2_k127_1370636_7	497964.CfE428DRAFT_1861	3.322e-45	185.0	COG1595@1|root,COG4194@1|root,COG1595@2|Bacteria,COG4194@2|Bacteria,46TQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_1370636_5	1210884.HG799464_gene10651	4.01e-121	402.0	COG1819@1|root,COG1819@2|Bacteria,2IZT0@203682|Planctomycetes	203682|Planctomycetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
ZZS2_k127_1370636_6	331113.SNE_A03330	1.117e-91	308.0	COG0789@1|root,COG0789@2|Bacteria,2JGKY@204428|Chlamydiae	204428|Chlamydiae	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
ZZS2_k127_1430516_11	1183438.GKIL_2649	3.923e-130	426.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
ZZS2_k127_1430516_4	1403819.BATR01000040_gene1212	9.71e-193	616.0	COG2939@1|root,COG2939@2|Bacteria,46UB7@74201|Verrucomicrobia,2IVCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
ZZS2_k127_1430516_31	304371.MCP_2981	4.02e-05	53.0	COG0456@1|root,arCOG00833@2157|Archaea,2XXV1@28890|Euryarchaeota	28890|Euryarchaeota	S	COG1246 N-acetylglutamate synthase and related acetyltransferases	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
ZZS2_k127_1430516_19	497964.CfE428DRAFT_5455	3.272e-72	249.0	COG2344@1|root,COG2344@2|Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
ZZS2_k127_1430516_16	55529.EKX47288	3.27e-90	312.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
ZZS2_k127_1430516_8	497964.CfE428DRAFT_3635	2.183e-144	479.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
ZZS2_k127_1430516_20	1384054.N790_12685	5.51e-71	253.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X36S@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xcsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
ZZS2_k127_1430516_25	1121382.JQKG01000025_gene3001	9.826e-12	76.0	COG1459@1|root,COG1459@2|Bacteria,1WIU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	PFAM Bacterial type II secretion system protein F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_1430516_30	349124.Hhal_0325	3.199e-05	57.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,1WZX4@135613|Chromatiales	135613|Chromatiales	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12278	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
ZZS2_k127_1430516_6	497964.CfE428DRAFT_3906	8.203e-157	499.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
ZZS2_k127_1430516_18	379066.GAU_3590	1.879e-77	273.0	COG0009@1|root,COG0009@2|Bacteria,1ZUMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
ZZS2_k127_1430516_27	525904.Tter_0083	1.497e-08	66.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8
ZZS2_k127_1430516_15	1070319.CAGGBEG34_190038	8.665e-109	370.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS2_k127_1430516_13	886293.Sinac_0380	6.288e-119	392.0	COG3391@1|root,COG3391@2|Bacteria,2IYVS@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
ZZS2_k127_1430516_14	497964.CfE428DRAFT_2969	1.053e-118	395.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
ZZS2_k127_1430516_24	1162668.LFE_0740	1.489e-17	87.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS2_k127_1430516_2	237368.SCABRO_03786	2.246e-271	856.0	COG0466@1|root,COG0466@2|Bacteria,2IYNA@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
ZZS2_k127_1430516_29	240016.ABIZ01000001_gene4443	5.476e-06	57.0	COG3026@1|root,COG3026@2|Bacteria,46W95@74201|Verrucomicrobia,2IUUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
ZZS2_k127_1430516_22	278957.ABEA03000130_gene1706	3.562e-61	216.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_1430516_3	278957.ABEA03000130_gene1701	3.312e-217	685.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
ZZS2_k127_1430516_21	278957.ABEA03000130_gene1697	6.972e-64	232.0	COG0457@1|root,COG0457@2|Bacteria	278957.ABEA03000130_gene1697|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1430516_9	278957.ABEA03000130_gene1696	1.068e-143	469.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	2|Bacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_1430516_17	1536773.R70331_00345	1.364e-81	278.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS2_k127_1430516_7	880072.Desac_0610	1.942e-156	505.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
ZZS2_k127_1430516_26	1229909.NSED_07760	3.684e-11	66.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1430516_10	497964.CfE428DRAFT_2462	5.222e-143	464.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
ZZS2_k127_1430516_23	671143.DAMO_2861	1.434e-31	129.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
ZZS2_k127_1430516_5	481448.Minf_0010	2.182e-180	573.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS2_k127_1430516_28	1123274.KB899421_gene1788	6.562e-07	60.0	COG1729@1|root,COG1729@2|Bacteria,2J7YF@203691|Spirochaetes	203691|Spirochaetes	S	TPR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_6,TPR_8
ZZS2_k127_1430516_1	497964.CfE428DRAFT_4431	5.055e-283	959.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
ZZS2_k127_1430516_12	215803.DB30_0441	2.525e-120	398.0	COG1063@1|root,COG1063@2|Bacteria,1NXSN@1224|Proteobacteria,438FZ@68525|delta/epsilon subdivisions,2X3QX@28221|Deltaproteobacteria,2YWVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
ZZS2_k127_1430516_0	497964.CfE428DRAFT_4464	0.0	1147.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
ZZS2_k127_1435077_2	1449976.KALB_1275	1.515e-102	344.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4DZ4D@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6
ZZS2_k127_1435077_5	204536.SULAZ_0487	3.57e-17	86.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ZZS2_k127_1435077_3	497964.CfE428DRAFT_6465	1.307e-81	278.0	COG3558@1|root,COG3558@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
ZZS2_k127_1435077_1	1210884.HG799464_gene10641	1.157e-105	377.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_1435077_0	314230.DSM3645_14810	1.185e-110	377.0	COG1520@1|root,COG1520@2|Bacteria,2IX03@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_1435077_4	497964.CfE428DRAFT_2098	5.312e-32	127.0	COG3791@1|root,COG3791@2|Bacteria,46T3T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM glutathione-dependent formaldehyde-activating GFA	-	-	-	-	-	-	-	-	-	-	-	-	GFA
ZZS2_k127_1449115_4	1396141.BATP01000051_gene3337	3.726e-05	47.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	LysM,PD40
ZZS2_k127_1449115_3	1396141.BATP01000051_gene3337	7.674e-08	53.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	LysM,PD40
ZZS2_k127_1449115_1	497964.CfE428DRAFT_4864	6.915e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1449115_0	886293.Sinac_6489	5.929e-109	391.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_1449115_2	1123278.KB893556_gene3773	3.57e-17	86.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1,Rhodanese
ZZS2_k127_1449945_3	216594.MMAR_0242	8.343e-35	153.0	COG0657@1|root,COG0823@1|root,COG0657@2|Bacteria,COG0823@2|Bacteria,2I40M@201174|Actinobacteria,233DD@1762|Mycobacteriaceae	201174|Actinobacteria	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE
ZZS2_k127_1449945_4	452637.Oter_4610	0.000272	54.0	COG3693@1|root,COG3693@2|Bacteria,46Z7R@74201|Verrucomicrobia	2|Bacteria	G	SMART Immunoglobulin C2 type	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
ZZS2_k127_1449945_0	382464.ABSI01000007_gene4191	1.53e-174	570.0	COG2833@1|root,COG2833@2|Bacteria,46YYE@74201|Verrucomicrobia,2ITUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
ZZS2_k127_1449945_1	794903.OPIT5_17520	3.091e-94	321.0	28JIN@1|root,30U02@2|Bacteria,46YTT@74201|Verrucomicrobia,3K7XH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1449945_2	497964.CfE428DRAFT_0782	4.995e-47	175.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,46UE9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
ZZS2_k127_1490293_1	1170562.Cal6303_0175	3.517e-31	144.0	COG2133@1|root,COG2931@1|root,COG3299@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3299@2|Bacteria,1G2CB@1117|Cyanobacteria,1HRM4@1161|Nostocales	1117|Cyanobacteria	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,PA14
ZZS2_k127_1490293_2	240016.ABIZ01000001_gene5499	0.0008379	53.0	COG2931@1|root,COG3203@1|root,COG3266@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3203@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,46VKK@74201|Verrucomicrobia,2IW2X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_1490293_0	1396141.BATP01000022_gene333	1.763e-67	263.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1503530_1	1123242.JH636436_gene131	5.86e-45	180.0	COG0750@1|root,COG0750@2|Bacteria,2IXR8@203682|Planctomycetes	203682|Planctomycetes	MO	MucD-putative a secreted serine proteinase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
ZZS2_k127_1503530_2	1303518.CCALI_02493	0.0001959	55.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
ZZS2_k127_1503530_0	359.CN09_08765	6.6e-137	441.0	COG3739@1|root,COG3739@2|Bacteria,1PMEC@1224|Proteobacteria,2TRGD@28211|Alphaproteobacteria,4BBTW@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF817
ZZS2_k127_1510721_32	1122179.KB890425_gene3464	4.847e-08	63.0	COG1397@1|root,COG1397@2|Bacteria,4P1DN@976|Bacteroidetes	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1510721_24	1403819.BATR01000098_gene3285	1.018e-34	137.0	COG1917@1|root,COG1917@2|Bacteria,46WE0@74201|Verrucomicrobia,2IVZR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_1510721_27	344747.PM8797T_19440	3.76e-20	96.0	COG5496@1|root,COG5496@2|Bacteria,2J4DW@203682|Planctomycetes	203682|Planctomycetes	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1510721_15	478741.JAFS01000002_gene444	8.937e-84	295.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,37G9H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
ZZS2_k127_1510721_6	1267535.KB906767_gene3872	1.726e-169	546.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnC	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
ZZS2_k127_1510721_11	1382359.JIAL01000001_gene1318	4.269e-119	398.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
ZZS2_k127_1510721_3	452637.Oter_2956	1.142e-209	661.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
ZZS2_k127_1510721_5	1396141.BATP01000062_gene4439	2.345e-192	610.0	COG0715@1|root,COG0715@2|Bacteria,46U3D@74201|Verrucomicrobia,2IU5R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
ZZS2_k127_1510721_12	240016.ABIZ01000001_gene4296	8.44e-116	378.0	COG0600@1|root,COG0600@2|Bacteria,46UK8@74201|Verrucomicrobia,2IUP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ZZS2_k127_1510721_13	1254432.SCE1572_24295	1.845e-111	370.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02049,ko:K15578,ko:K15579	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	ABC_tran
ZZS2_k127_1510721_10	1396418.BATQ01000051_gene60	2.972e-119	390.0	COG1116@1|root,COG1116@2|Bacteria,46UJC@74201|Verrucomicrobia,2ITHC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_1510721_7	240016.ABIZ01000001_gene4306	5.875e-139	460.0	COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,46UBK@74201|Verrucomicrobia,2IU0J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	DMSO reductase anchor subunit (DmsC)	-	-	-	-	-	-	-	-	-	-	-	-	DmsC,Fer4_11
ZZS2_k127_1510721_0	448385.sce8491	3.188e-317	992.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2X7DH@28221|Deltaproteobacteria,2YWG8@29|Myxococcales	68525|delta/epsilon subdivisions	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS2_k127_1510721_1	452637.Oter_1737	1.523e-214	681.0	COG0155@1|root,COG0155@2|Bacteria,46TDQ@74201|Verrucomicrobia,3K7TZ@414999|Opitutae	414999|Opitutae	C	nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein	-	-	1.7.7.1	ko:K00366	ko00910,ko01120,map00910,map01120	M00531	R00790	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
ZZS2_k127_1510721_2	497964.CfE428DRAFT_4918	5.335e-210	668.0	COG0369@1|root,COG0369@2|Bacteria,46SEE@74201|Verrucomicrobia	74201|Verrucomicrobia	P	oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
ZZS2_k127_1510721_9	497964.CfE428DRAFT_2202	4.267e-120	408.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_1510721_34	1121890.AUDO01000005_gene1545	1.542e-05	50.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,2P0RA@237|Flavobacterium	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Endonuclease_1,LTD,MAM,SprB,fn3
ZZS2_k127_1510721_16	517418.Ctha_2578	5.056e-81	287.0	COG0477@1|root,COG2814@2|Bacteria,1FD9X@1090|Chlorobi	1090|Chlorobi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
ZZS2_k127_1510721_20	1210884.HG799465_gene11380	5.589e-54	218.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_1510721_4	886293.Sinac_2090	3.181e-193	609.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
ZZS2_k127_1510721_17	382464.ABSI01000010_gene3794	1.659e-61	235.0	COG4888@1|root,COG4888@2|Bacteria,46UDG@74201|Verrucomicrobia	2|Bacteria	O	PFAM ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_1510721_31	1236973.JCM9157_2913	1.16e-09	69.0	COG3266@1|root,COG3266@2|Bacteria,1VDA3@1239|Firmicutes,4ITGR@91061|Bacilli,1ZDHT@1386|Bacillus	91061|Bacilli	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,TPR_19
ZZS2_k127_1510721_30	717774.Marme_1436	5.317e-12	68.0	COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,1XM2R@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
ZZS2_k127_1510721_22	382464.ABSI01000014_gene1430	1.916e-48	181.0	COG2716@1|root,COG2716@2|Bacteria,46VWB@74201|Verrucomicrobia,2IVUS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
ZZS2_k127_1510721_23	1123070.KB899256_gene2167	1.2e-44	169.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia,2IUIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1510721_28	452637.Oter_3780	5.772e-18	94.0	COG5662@1|root,COG5662@2|Bacteria,46VJ8@74201|Verrucomicrobia,3K9W5@414999|Opitutae	414999|Opitutae	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1510721_29	794903.OPIT5_29655	1.603e-14	84.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_29655|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1510721_21	204669.Acid345_2517	1.911e-49	186.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
ZZS2_k127_1510721_25	397948.Cmaq_1622	2.827e-30	136.0	COG1593@1|root,arCOG08625@2157|Archaea	2157|Archaea	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
ZZS2_k127_1510721_26	452637.Oter_4589	4.666e-21	94.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia,3K8CU@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1510721_19	383372.Rcas_2433	3.089e-54	196.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
ZZS2_k127_1510721_8	497964.CfE428DRAFT_2607	1.265e-131	427.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS2_k127_1510721_14	497964.CfE428DRAFT_0699	1.654e-88	310.0	COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS2_k127_1510721_18	240016.ABIZ01000001_gene5892	1.496e-58	208.0	COG0698@1|root,COG0698@2|Bacteria,46STF@74201|Verrucomicrobia,2IUD9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribose/Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	LacAB_rpiB
ZZS2_k127_1518647_6	1540221.JQNI01000002_gene1258	1.104e-10	74.0	COG3525@1|root,COG3525@2|Bacteria,1WM65@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
ZZS2_k127_1518647_3	497964.CfE428DRAFT_4900	1.972e-79	273.0	COG1442@1|root,COG1442@2|Bacteria	2|Bacteria	M	lipopolysaccharide 3-alpha-galactosyltransferase activity	kdsB2	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8,Glycos_transf_2
ZZS2_k127_1518647_1	240016.ABIZ01000001_gene824	2.641e-130	426.0	COG0859@1|root,COG0859@2|Bacteria,46TJT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Mannosyl_trans3
ZZS2_k127_1518647_5	202698.XP_007385805.1	3.146e-15	91.0	KOG0272@1|root,KOG0272@2759|Eukaryota,39QIX@33154|Opisthokonta,3Q6NI@4751|Fungi,3V7TN@5204|Basidiomycota,22BMH@155619|Agaricomycetes,3H6TQ@355688|Agaricomycetes incertae sedis	4751|Fungi	A	WD40 repeat-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235,WD40
ZZS2_k127_1518647_2	765913.ThidrDRAFT_4513	6.584e-123	435.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1R3SH@1224|Proteobacteria,1S6CN@1236|Gammaproteobacteria,1WZCC@135613|Chromatiales	135613|Chromatiales	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1518647_0	765913.ThidrDRAFT_4512	6.964e-139	473.0	COG1672@1|root,COG1672@2|Bacteria,1NTWM@1224|Proteobacteria	1224|Proteobacteria	O	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,TIR_2,Trypsin_2
ZZS2_k127_1518647_4	497964.CfE428DRAFT_0066	3.355e-68	261.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_1518647_7	1304874.JAFY01000002_gene1022	3.13e-05	57.0	COG1462@1|root,COG1462@2|Bacteria,3TB3V@508458|Synergistetes	508458|Synergistetes	M	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
ZZS2_k127_1530646_0	616991.JPOO01000001_gene4357	1.298e-87	299.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1INBR@117743|Flavobacteriia,23I1Y@178469|Arenibacter	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	tolB3	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_1530646_3	314230.DSM3645_09707	6.463e-26	113.0	2E13H@1|root,32WIX@2|Bacteria,2J0HQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1530646_2	1123508.JH636450_gene7204	4.012e-67	241.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_1530646_1	497964.CfE428DRAFT_6227	5.822e-70	247.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
ZZS2_k127_1547845_4	1121943.KB899991_gene2383	0.0002066	55.0	COG2885@1|root,COG2885@2|Bacteria,1RENP@1224|Proteobacteria,1S4IW@1236|Gammaproteobacteria,1XJ8G@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	oprF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
ZZS2_k127_1547845_0	1121897.AUGO01000002_gene2177	2.203e-72	279.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_1547845_3	1396141.BATP01000025_gene938	6.603e-10	74.0	COG2730@1|root,COG2755@1|root,COG2931@1|root,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,Calx-beta,Lipase_GDSL_2
ZZS2_k127_1547845_2	324057.Pjdr2_4676	3.437e-34	154.0	COG1409@1|root,COG3291@1|root,COG3537@1|root,COG3693@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG3537@2|Bacteria,COG3693@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26VY4@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92
ZZS2_k127_1547845_1	1894.JOER01000058_gene3221	1.398e-65	238.0	COG0265@1|root,COG2319@1|root,COG0265@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
ZZS2_k127_1552671_0	1337936.IJ00_01065	7.992e-66	248.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
ZZS2_k127_1552671_1	1297742.A176_01345	4.137e-12	74.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
ZZS2_k127_1560154_13	1396141.BATP01000039_gene1303	6.098e-23	102.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
ZZS2_k127_1560154_10	886293.Sinac_1624	6.847e-107	354.0	COG0546@1|root,COG0546@2|Bacteria,2IYT6@203682|Planctomycetes	203682|Planctomycetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS2_k127_1560154_12	388413.ALPR1_06400	1.545e-37	148.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,47NH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1560154_14	82654.Pse7367_1552	2.793e-21	99.0	2E363@1|root,32Y5Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1560154_11	65393.PCC7424_1997	8.934e-39	166.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G4IS@1117|Cyanobacteria,3KKQ9@43988|Cyanothece	1117|Cyanobacteria	QU	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
ZZS2_k127_1560154_2	452637.Oter_3674	2.141e-290	903.0	COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia,3K7DH@414999|Opitutae	414999|Opitutae	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
ZZS2_k127_1560154_6	713586.KB900536_gene49	1.55e-212	688.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,1T1IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
ZZS2_k127_1560154_1	264732.Moth_1810	6.128e-303	948.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
ZZS2_k127_1560154_5	264732.Moth_1809	1.075e-228	723.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
ZZS2_k127_1560154_9	1382356.JQMP01000004_gene488	3.46e-130	433.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
ZZS2_k127_1560154_8	1121468.AUBR01000021_gene2827	1.775e-169	557.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
ZZS2_k127_1560154_0	479434.Sthe_1092	0.0	1359.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
ZZS2_k127_1560154_3	452637.Oter_1105	3.181e-257	811.0	COG0366@1|root,COG0366@2|Bacteria,46S7A@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
ZZS2_k127_1560154_7	867903.ThesuDRAFT_01213	3.624e-176	564.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,25F3I@186801|Clostridia,3WCCI@538999|Clostridiales incertae sedis	186801|Clostridia	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
ZZS2_k127_1560154_4	452637.Oter_1362	1.362e-234	739.0	COG3664@1|root,COG3664@2|Bacteria	2|Bacteria	G	PFAM glycoside hydrolase family 39	xynB	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
ZZS2_k127_1563022_2	497964.CfE428DRAFT_0749	2.078e-85	288.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
ZZS2_k127_1563022_0	1449063.JMLS01000019_gene5648	5.204e-251	782.0	COG2303@1|root,COG2303@2|Bacteria,1TSGS@1239|Firmicutes,4HE6B@91061|Bacilli,26XXV@186822|Paenibacillaceae	91061|Bacilli	E	GMC oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
ZZS2_k127_1563022_1	1396141.BATP01000057_gene2932	6.814e-105	349.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Cadherin,Cadherin-like,Calycin_like,Chondroitinas_B,F5_F8_type_C,GSDH,Laminin_G_3,PA14,PCMD,SLH
ZZS2_k127_1580439_0	497964.CfE428DRAFT_4863	1.772e-40	168.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1580439_2	886293.Sinac_0140	1.974e-05	56.0	2EGZK@1|root,33ARQ@2|Bacteria,2J4A7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1580439_1	1042376.AFPK01000069_gene638	3.399e-11	72.0	COG5492@1|root,COG5492@2|Bacteria,4P01H@976|Bacteroidetes,1I7T9@117743|Flavobacteriia,406ZU@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	NQ	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
ZZS2_k127_1580439_3	886293.Sinac_0140	0.0001191	50.0	2EGZK@1|root,33ARQ@2|Bacteria,2J4A7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1595194_2	1123073.KB899241_gene3101	2.064e-81	274.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XCBQ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_1595194_0	935948.KE386494_gene750	8.3e-133	444.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42EQB@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_1595194_1	357808.RoseRS_2719	1.457e-122	417.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_1595194_3	644968.DFW101_1764	6.31e-75	266.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,42Z4V@68525|delta/epsilon subdivisions,2WU31@28221|Deltaproteobacteria,2MFW4@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
ZZS2_k127_1595194_4	398767.Glov_0596	5.303e-72	261.0	COG1785@1|root,COG4222@1|root,COG1785@2|Bacteria,COG4222@2|Bacteria,1MXI2@1224|Proteobacteria,42N40@68525|delta/epsilon subdivisions,2WKUV@28221|Deltaproteobacteria,43V5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
ZZS2_k127_1595194_5	246197.MXAN_7373	9.827e-49	184.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,42Z3U@68525|delta/epsilon subdivisions,2WU4D@28221|Deltaproteobacteria,2YVGW@29|Myxococcales	28221|Deltaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1617280_6	497964.CfE428DRAFT_2502	9.744e-187	608.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
ZZS2_k127_1617280_7	497964.CfE428DRAFT_1244	5.765e-116	380.0	COG0583@1|root,COG0583@2|Bacteria,46TNE@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_1617280_0	748280.NH8B_1377	0.0	1229.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
ZZS2_k127_1617280_4	497964.CfE428DRAFT_6594	1.599e-206	648.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_1617280_9	273075.Ta0352	6.294e-61	221.0	COG1545@1|root,arCOG01287@2157|Archaea,2Y7AV@28890|Euryarchaeota,2427M@183967|Thermoplasmata	183967|Thermoplasmata	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
ZZS2_k127_1617280_2	497964.CfE428DRAFT_6592	2.847e-267	833.0	COG1960@1|root,COG1960@2|Bacteria,46TJY@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_1617280_3	497964.CfE428DRAFT_6591	9.174e-241	756.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_1617280_5	246194.CHY_0572	1.289e-202	643.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,25AZ5@186801|Clostridia,42FPZ@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM AMP-dependent synthetase	-	-	6.2.1.1,6.2.1.2	ko:K01895,ko:K01896	ko00010,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01176,R01354	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_1617280_1	518766.Rmar_1427	2.084e-280	876.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1FIMS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS2_k127_1617280_8	1170562.Cal6303_1111	3.053e-76	267.0	COG0604@1|root,COG0604@2|Bacteria,1FZW8@1117|Cyanobacteria,1HKMY@1161|Nostocales	1117|Cyanobacteria	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
ZZS2_k127_1629505_13	1158165.KB898871_gene2270	2.944e-57	211.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
ZZS2_k127_1629505_12	497964.CfE428DRAFT_2694	1.396e-60	239.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
ZZS2_k127_1629505_7	497964.CfE428DRAFT_4611	5.744e-103	357.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS2_k127_1629505_3	497964.CfE428DRAFT_4613	1.538e-151	485.0	COG0451@1|root,COG0451@2|Bacteria,46S80@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS2_k127_1629505_5	497964.CfE428DRAFT_4614	4.507e-123	409.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS2_k127_1629505_4	1396418.BATQ01000015_gene4322	1.426e-148	491.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS2_k127_1629505_6	1403819.BATR01000052_gene1571	3.51e-105	367.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
ZZS2_k127_1629505_1	1396418.BATQ01000015_gene4320	9.694e-286	895.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,46W5Q@74201|Verrucomicrobia	74201|Verrucomicrobia	E	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
ZZS2_k127_1629505_10	1168034.FH5T_12290	5.613e-64	233.0	COG0079@1|root,COG0079@2|Bacteria,4NPC4@976|Bacteroidetes,2FPHU@200643|Bacteroidia	976|Bacteroidetes	EM	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,NTP_transf_3,NTP_transferase
ZZS2_k127_1629505_16	670292.JH26_16730	2.729e-42	173.0	COG1541@1|root,COG1541@2|Bacteria,1R7WG@1224|Proteobacteria,2U4M0@28211|Alphaproteobacteria,1JWE6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
ZZS2_k127_1629505_18	351160.RCIX2096	1.656e-24	114.0	COG0613@1|root,arCOG00302@2157|Archaea,2XT0K@28890|Euryarchaeota,2NAUQ@224756|Methanomicrobia	224756|Methanomicrobia	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
ZZS2_k127_1629505_9	936573.HMPREF1147_2349	2.079e-66	244.0	COG2006@1|root,COG2006@2|Bacteria,1UZV2@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
ZZS2_k127_1629505_14	1243664.CAVL020000022_gene2592	1.425e-56	216.0	COG1541@1|root,COG1541@2|Bacteria,1V5FH@1239|Firmicutes,4HME3@91061|Bacilli	91061|Bacilli	H	coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
ZZS2_k127_1629505_19	41431.PCC8801_0079	4.184e-11	74.0	28IA6@1|root,2Z8CT@2|Bacteria,1G3HX@1117|Cyanobacteria,3KGZP@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1629505_8	41431.PCC8801_0030	7.099e-98	340.0	COG1696@1|root,COG1696@2|Bacteria,1G195@1117|Cyanobacteria,3KHJQ@43988|Cyanothece	1117|Cyanobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
ZZS2_k127_1629505_11	240016.ABIZ01000001_gene3453	5.042e-62	228.0	COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_1629505_15	929556.Solca_1804	2.886e-47	173.0	COG0824@1|root,COG0824@2|Bacteria,4NR6U@976|Bacteroidetes,1ISVV@117747|Sphingobacteriia	976|Bacteroidetes	S	thioesterase	-	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	Acyl-ACP_TE
ZZS2_k127_1629505_0	452637.Oter_2954	6.641e-314	996.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1629505_17	1144275.COCOR_00598	1.376e-35	150.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,42RP4@68525|delta/epsilon subdivisions,2WPU8@28221|Deltaproteobacteria,2YWQD@29|Myxococcales	28221|Deltaproteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
ZZS2_k127_1629505_2	1396418.BATQ01000117_gene4519	2.179e-176	557.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_1631328_5	760192.Halhy_1303	8.816e-70	249.0	COG1879@1|root,COG1879@2|Bacteria,4NKXR@976|Bacteroidetes	976|Bacteroidetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS2_k127_1631328_4	1297570.MESS4_340149	2.338e-75	265.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TV15@28211|Alphaproteobacteria,43QWW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
ZZS2_k127_1631328_0	1172181.KB911703_gene378	6.035e-138	455.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
ZZS2_k127_1631328_3	525904.Tter_1997	2.924e-94	319.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_1631328_2	1040986.ATYO01000017_gene886	6.803e-95	320.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VEXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
ZZS2_k127_1631328_1	61459.XP_007785182.1	1.593e-123	416.0	COG2084@1|root,KOG0409@2759|Eukaryota,39DA8@33154|Opisthokonta,3NU8U@4751|Fungi,3QPIP@4890|Ascomycota,20JXN@147545|Eurotiomycetes,3MVAU@451870|Chaetothyriomycetidae	4751|Fungi	I	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537,NAD_binding_11,NAD_binding_2
ZZS2_k127_1631328_6	243090.RB3774	1.888e-32	139.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
ZZS2_k127_1642232_6	478741.JAFS01000001_gene1842	6.143e-151	488.0	COG0642@1|root,COG2205@2|Bacteria,46UHY@74201|Verrucomicrobia,37GB8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
ZZS2_k127_1642232_10	1403819.BATR01000007_gene219	1.036e-71	259.0	COG2156@1|root,COG2156@2|Bacteria,46SYC@74201|Verrucomicrobia,2IVFX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	-	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
ZZS2_k127_1642232_0	240016.ABIZ01000001_gene5272	0.0	1020.0	COG2216@1|root,COG2216@2|Bacteria,46SEM@74201|Verrucomicrobia,2ITIQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	-	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
ZZS2_k127_1642232_1	240016.ABIZ01000001_gene5273	3.586e-305	944.0	COG2060@1|root,COG2060@2|Bacteria,46S9Y@74201|Verrucomicrobia,2ITVE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	-	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
ZZS2_k127_1642232_4	1121918.ARWE01000001_gene3150	1.787e-239	756.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
ZZS2_k127_1642232_5	1396141.BATP01000045_gene1796	1.171e-179	576.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	ko:K21164	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	p450
ZZS2_k127_1642232_11	671143.DAMO_0795	3.077e-09	70.0	28VTP@1|root,2ZHVD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1642232_3	1210884.HG799470_gene14529	3.544e-252	799.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_1642232_2	1121920.AUAU01000006_gene306	1.596e-283	899.0	COG1506@1|root,COG1506@2|Bacteria,3Y2HK@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_1642232_8	497964.CfE428DRAFT_1977	1.535e-112	366.0	COG1051@1|root,COG1051@2|Bacteria,46SHC@74201|Verrucomicrobia	74201|Verrucomicrobia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
ZZS2_k127_1642232_7	497964.CfE428DRAFT_1982	9.61e-144	464.0	COG0330@1|root,COG0330@2|Bacteria,46U2V@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_1642232_9	497964.CfE428DRAFT_1983	2.941e-73	250.0	COG0061@1|root,COG0061@2|Bacteria,46UHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1666802_2	234267.Acid_5128	1.178e-46	185.0	29V32@1|root,30GGD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1666802_0	99598.Cal7507_3741	1.81e-109	362.0	29137@1|root,2ZNQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1666802_1	99598.Cal7507_3740	1.056e-68	243.0	COG4447@1|root,COG4447@2|Bacteria,1G5IX@1117|Cyanobacteria	1117|Cyanobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Peptidase_S74
ZZS2_k127_1667929_6	1380387.JADM01000009_gene3200	2.019e-30	122.0	COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,1SAJC@1236|Gammaproteobacteria,1XN13@135619|Oceanospirillales	135619|Oceanospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_1667929_5	1122135.KB893138_gene1110	1.606e-35	140.0	COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_1667929_4	497964.CfE428DRAFT_5990	1.428e-39	155.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1667929_8	1267534.KB906760_gene1563	1.319e-16	82.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1667929_0	1116472.MGMO_17c00060	3.716e-206	661.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XEIK@135618|Methylococcales	135618|Methylococcales	KT	PFAM RNA polymerase sigma factor 54, interaction	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
ZZS2_k127_1667929_2	118173.KB235914_gene2350	9.915e-107	357.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1H8TZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_1667929_3	489825.LYNGBM3L_01300	6.827e-50	187.0	29EN4@1|root,301K2@2|Bacteria,1G4I6@1117|Cyanobacteria,1HET5@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1667929_1	504472.Slin_2526	2.798e-122	404.0	COG2146@1|root,COG2717@1|root,COG2146@2|Bacteria,COG2717@2|Bacteria,4NJUW@976|Bacteroidetes,47TAG@768503|Cytophagia	976|Bacteroidetes	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct,Rieske
ZZS2_k127_1667929_10	329726.AM1_4157	9.667e-06	55.0	2DEUC@1|root,32U42@2|Bacteria,1G8FM@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1667929_7	272559.BF9343_2366	3.176e-17	85.0	COG4828@1|root,COG4828@2|Bacteria,4NTSB@976|Bacteroidetes,2FT4V@200643|Bacteroidia,4ARD2@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
ZZS2_k127_1672557_1	1157632.AQWQ01000015_gene3403	0.000927	54.0	COG3204@1|root,COG3204@2|Bacteria,2I94U@201174|Actinobacteria	201174|Actinobacteria	K	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
ZZS2_k127_1672557_0	1396141.BATP01000034_gene4198	2.443e-268	892.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_1674283_0	497964.CfE428DRAFT_2932	1.389e-153	505.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_1674283_3	478741.JAFS01000001_gene1134	1.601e-83	289.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,37GF6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
ZZS2_k127_1674283_7	1304872.JAGC01000009_gene431	2.167e-10	72.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2MAW5@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
ZZS2_k127_1674283_1	497964.CfE428DRAFT_2928	8.355e-113	377.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
ZZS2_k127_1674283_4	794903.OPIT5_03600	1.442e-70	255.0	COG0206@1|root,COG0206@2|Bacteria,46UAJ@74201|Verrucomicrobia,3K7KG@414999|Opitutae	414999|Opitutae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
ZZS2_k127_1674283_5	497964.CfE428DRAFT_0672	1.72e-54	209.0	COG1253@1|root,COG1253@2|Bacteria,46VJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC,DUF21
ZZS2_k127_1674283_6	497964.CfE428DRAFT_0673	1.234e-19	100.0	COG1253@1|root,COG1253@2|Bacteria,46W8Q@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
ZZS2_k127_1674283_2	1009370.ALO_20077	1.006e-104	355.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H2XJ@909932|Negativicutes	909932|Negativicutes	S	CBS domain	ytfL_2	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
ZZS2_k127_1674389_5	278963.ATWD01000001_gene3285	9.169e-39	147.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
ZZS2_k127_1674389_0	1267535.KB906767_gene3530	1.436e-221	717.0	COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria,2JMJ0@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_1674389_10	526225.Gobs_0751	2.836e-09	66.0	COG0568@1|root,COG0568@2|Bacteria,2H4XN@201174|Actinobacteria	201174|Actinobacteria	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1674389_8	671143.DAMO_2521	2.005e-25	109.0	COG1848@1|root,COG1848@2|Bacteria,2NRZX@2323|unclassified Bacteria	2|Bacteria	S	PIN domain	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
ZZS2_k127_1674389_11	1126627.BAWE01000004_gene3147	2.221e-05	51.0	COG2002@1|root,COG2002@2|Bacteria,1N3BE@1224|Proteobacteria,2UBXQ@28211|Alphaproteobacteria,3K0DZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
ZZS2_k127_1674389_12	1408813.AYMG01000012_gene1047	0.0001109	47.0	COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes,1IRPS@117747|Sphingobacteriia	976|Bacteroidetes	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
ZZS2_k127_1674389_6	1173026.Glo7428_2495	1.21e-32	145.0	COG3420@1|root,COG3420@2|Bacteria,1G13S@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_1674389_2	344747.PM8797T_21733	7.557e-102	349.0	COG3356@1|root,COG3356@2|Bacteria,2IX5S@203682|Planctomycetes	2|Bacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
ZZS2_k127_1674389_3	344747.PM8797T_30856	8.193e-71	246.0	COG0412@1|root,COG0412@2|Bacteria,2IYJ7@203682|Planctomycetes	203682|Planctomycetes	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1674389_9	1122185.N792_08155	1.72e-12	68.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,1S9PQ@1236|Gammaproteobacteria,1X7R6@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
ZZS2_k127_1674389_7	1123388.AQWU01000050_gene572	5.011e-30	132.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1674389_1	1123242.JH636434_gene3495	4.512e-141	492.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_17227_0	1267534.KB906754_gene3778	1.701e-178	564.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
ZZS2_k127_17227_3	378806.STAUR_5443	1.459e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_17227_1	56110.Oscil6304_1643	1.569e-134	453.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
ZZS2_k127_17227_2	314345.SPV1_01182	1.929e-49	187.0	28N94@1|root,2ZBD8@2|Bacteria,1MWA4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_172663_1	595460.RRSWK_06785	6.817e-84	298.0	COG0515@1|root,COG0515@2|Bacteria,2J0PH@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_172663_3	1403819.BATR01000083_gene2425	4.776e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46TV8@74201|Verrucomicrobia,2IVT7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_172663_2	1089547.KB913013_gene3291	1.61e-75	273.0	COG2333@1|root,COG2333@2|Bacteria,4NN5Y@976|Bacteroidetes,47QYX@768503|Cytophagia	976|Bacteroidetes	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS2_k127_172663_0	1089547.KB913013_gene3292	5.4e-168	550.0	COG3590@1|root,COG3590@2|Bacteria,4NKGB@976|Bacteroidetes,47JNY@768503|Cytophagia	976|Bacteroidetes	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_172663_4	886293.Sinac_0410	3.737e-22	109.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_172663_5	1408473.JHXO01000001_gene2203	0.0004271	54.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NKPC@976|Bacteroidetes,2G0FQ@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
ZZS2_k127_1758763_8	266117.Rxyl_1327	9.266e-68	235.0	COG2514@1|root,COG2514@2|Bacteria,2HNS6@201174|Actinobacteria,4CPZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
ZZS2_k127_1758763_6	163908.KB235896_gene4833	5.154e-104	343.0	COG1028@1|root,COG1028@2|Bacteria,1G604@1117|Cyanobacteria,1HMRT@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_1758763_5	652103.Rpdx1_3416	2.406e-126	421.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria,3K6S8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
ZZS2_k127_1758763_3	234267.Acid_5490	7.259e-176	574.0	COG3420@1|root,COG3420@2|Bacteria,3Y67Z@57723|Acidobacteria	57723|Acidobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_1758763_7	449447.MAE_12850	3.434e-81	281.0	COG1805@1|root,COG1805@2|Bacteria	2|Bacteria	C	FMN binding	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	NQR2_RnfD_RnfE
ZZS2_k127_1758763_1	497965.Cyan7822_0306	1.02e-215	687.0	COG4658@1|root,COG4658@2|Bacteria,1GBPJ@1117|Cyanobacteria	1117|Cyanobacteria	C	ASPIC and UnbV	-	-	-	ko:K21162	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_1758763_13	246197.MXAN_3277	1.731e-44	175.0	COG2128@1|root,COG2128@2|Bacteria,1Q58P@1224|Proteobacteria,43A55@68525|delta/epsilon subdivisions,2WZAF@28221|Deltaproteobacteria,2Z1PY@29|Myxococcales	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1758763_12	518766.Rmar_1172	1.255e-46	183.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,4PEVF@976|Bacteroidetes,1FJP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
ZZS2_k127_1758763_0	452637.Oter_2327	1.951e-244	783.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1758763_9	1122604.JONR01000033_gene34	1.815e-64	229.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
ZZS2_k127_1758763_4	1173028.ANKO01000151_gene5291	2.937e-128	426.0	COG0671@1|root,COG2931@1|root,COG0671@2|Bacteria,COG2931@2|Bacteria,1G3V2@1117|Cyanobacteria,1H9MJ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PAP2
ZZS2_k127_1758763_2	452637.Oter_0301	7.301e-185	584.0	COG0500@1|root,COG2226@2|Bacteria,46TWV@74201|Verrucomicrobia	2|Bacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
ZZS2_k127_1762367_3	1121939.L861_10685	6.856e-120	393.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XIZ0@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
ZZS2_k127_1762367_0	1041139.KB902687_gene1250	1.256e-258	805.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,4B9EB@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Arylsulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
ZZS2_k127_1762367_4	1169161.KB897720_gene3813	1.914e-46	173.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
ZZS2_k127_1762367_1	1396418.BATQ01000141_gene3316	1.239e-208	661.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,46T20@74201|Verrucomicrobia,2IV2R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	AlkA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
ZZS2_k127_1762367_2	452637.Oter_1068	3.765e-146	469.0	COG0435@1|root,COG0435@2|Bacteria,46S81@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
ZZS2_k127_1762367_5	215803.DB30_8307	5.126e-15	85.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
ZZS2_k127_1779774_1	1121904.ARBP01000008_gene3255	2.339e-143	458.0	COG4948@1|root,COG4948@2|Bacteria,4NEPP@976|Bacteroidetes,47M8J@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_1779774_3	1396418.BATQ01000056_gene226	2.893e-40	154.0	COG3795@1|root,COG3795@2|Bacteria,46VU9@74201|Verrucomicrobia,2IVWF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_1779774_0	1396418.BATQ01000056_gene225	2.575e-167	535.0	COG4941@1|root,COG4941@2|Bacteria,46SEY@74201|Verrucomicrobia,2IV8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_1779774_2	1128421.JAGA01000003_gene2905	1.767e-132	439.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
ZZS2_k127_1787054_1	382464.ABSI01000010_gene3258	2.725e-273	884.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1787054_3	1120963.KB894499_gene422	3.074e-215	743.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_1787054_9	1056820.KB900684_gene9	3.873e-14	89.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1N3NA@1224|Proteobacteria,1S9U5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Pretoxin HINT domain	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS
ZZS2_k127_1787054_6	452637.Oter_2930	6.573e-54	194.0	COG2193@1|root,COG2193@2|Bacteria,46V17@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM Ferritin Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
ZZS2_k127_1787054_10	45157.CMT484CT	1.308e-07	59.0	COG5054@1|root,KOG3355@2759|Eukaryota	2759|Eukaryota	O	flavin-linked sulfhydryl oxidase activity	GFER	GO:0000166,GO:0001889,GO:0001910,GO:0001911,GO:0002237,GO:0002682,GO:0002683,GO:0002697,GO:0002698,GO:0002703,GO:0002704,GO:0002706,GO:0002707,GO:0002715,GO:0002716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006950,GO:0007275,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009636,GO:0009719,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010556,GO:0010557,GO:0010604,GO:0010941,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016670,GO:0016971,GO:0016972,GO:0019219,GO:0019222,GO:0031099,GO:0031100,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031341,GO:0031342,GO:0031347,GO:0031348,GO:0032496,GO:0032501,GO:0032502,GO:0033993,GO:0034097,GO:0034612,GO:0036094,GO:0040007,GO:0042060,GO:0042221,GO:0042246,GO:0042269,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045824,GO:0045935,GO:0045953,GO:0046677,GO:0048037,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048731,GO:0048732,GO:0048856,GO:0050660,GO:0050662,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0051704,GO:0051707,GO:0051716,GO:0055114,GO:0060255,GO:0060548,GO:0061008,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071236,GO:0071310,GO:0071345,GO:0071356,GO:0071396,GO:0071417,GO:0071495,GO:0072716,GO:0072717,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:0097237,GO:0097421,GO:1900407,GO:1900408,GO:1901214,GO:1901215,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902882,GO:1902883,GO:1903201,GO:1903202,GO:1903203,GO:1903204,GO:2000112,GO:2000278,GO:2000573	1.8.3.2	ko:K17783	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Evr1_Alr
ZZS2_k127_1787054_4	497964.CfE428DRAFT_6290	1.124e-95	323.0	COG1082@1|root,COG1082@2|Bacteria,46T96@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_1787054_0	392499.Swit_2667	1.589e-286	893.0	COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,2TR6R@28211|Alphaproteobacteria,2K13P@204457|Sphingomonadales	204457|Sphingomonadales	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
ZZS2_k127_1787054_8	644968.DFW101_1598	3.032e-18	100.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_1787054_5	382464.ABSI01000011_gene2968	1.44e-60	233.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1787054_7	497964.CfE428DRAFT_4864	6.589e-52	193.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1787054_2	927677.ALVU02000001_gene4596	4.481e-271	861.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1GAED@1117|Cyanobacteria	1117|Cyanobacteria	C	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS2_k127_1848428_0	909663.KI867151_gene3000	1.55e-140	456.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MQYT@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
ZZS2_k127_1848428_2	1121013.P873_03075	2.434e-50	194.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	czcO	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
ZZS2_k127_1848428_1	1121957.ATVL01000013_gene61	4.576e-107	367.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
ZZS2_k127_1854558_5	1210884.HG799472_gene14889	9.917e-56	199.0	COG0500@1|root,COG2226@2|Bacteria,2IZB5@203682|Planctomycetes	203682|Planctomycetes	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
ZZS2_k127_1854558_3	926549.KI421517_gene2071	4.633e-109	356.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,47KEE@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
ZZS2_k127_1854558_1	497964.CfE428DRAFT_1483	3.595e-202	636.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_1854558_4	429009.Adeg_1150	6.675e-60	220.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,42GDJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
ZZS2_k127_1854558_2	2903.EOD40718	5.087e-132	435.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
ZZS2_k127_1854558_6	1156937.MFUM_170017	2.952e-44	171.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,46SFD@74201|Verrucomicrobia,37GE0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
ZZS2_k127_1854558_7	1396418.BATQ01000073_gene500	5.284e-37	147.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS2_k127_1854558_0	644282.Deba_3187	6.438e-245	773.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS2_k127_1854558_8	84588.SYNW0439	0.0003182	51.0	COG2227@1|root,COG2227@2|Bacteria,1GFI9@1117|Cyanobacteria	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1857495_10	118161.KB235922_gene649	1.541e-10	71.0	COG0457@1|root,COG0457@2|Bacteria,1GIUM@1117|Cyanobacteria,3VMUI@52604|Pleurocapsales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
ZZS2_k127_1857495_11	587753.EY04_02975	8.923e-06	53.0	COG0848@1|root,COG0848@2|Bacteria,1RJZC@1224|Proteobacteria,1S4SP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_1857495_1	497964.CfE428DRAFT_1756	4.456e-78	272.0	COG2207@1|root,COG2207@2|Bacteria,46T4M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, arabinose operon control protein	araC	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS2_k127_1857495_6	1396418.BATQ01000046_gene6121	1.968e-27	113.0	COG0640@1|root,COG0640@2|Bacteria,46W65@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS2_k127_1857495_0	1094980.Mpsy_0015	1.833e-132	436.0	COG2133@1|root,COG3794@1|root,arCOG10180@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,arCOG10180@2157|Archaea,2XT1Q@28890|Euryarchaeota,2NADP@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
ZZS2_k127_1857495_4	497964.CfE428DRAFT_3450	4.677e-58	209.0	COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
ZZS2_k127_1857495_9	717785.HYPMC_3214	6.567e-20	94.0	COG2940@1|root,COG2940@2|Bacteria,1N3VM@1224|Proteobacteria,2UDY0@28211|Alphaproteobacteria,3N93Y@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
ZZS2_k127_1857495_8	344747.PM8797T_00177	4.305e-24	115.0	2ESRG@1|root,33K9V@2|Bacteria,2J33K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1857495_3	344747.PM8797T_12328	5.231e-60	229.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Peptidase_S9
ZZS2_k127_1857495_5	886293.Sinac_6278	3.284e-47	194.0	COG4219@1|root,COG4219@2|Bacteria,2J205@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Thioredoxin_7
ZZS2_k127_1857495_7	886293.Sinac_6279	4.529e-27	115.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
ZZS2_k127_1890701_33	1305737.JAFX01000001_gene3410	4.134e-42	161.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_1890701_11	1303518.CCALI_00532	9.262e-163	520.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
ZZS2_k127_1890701_8	857293.CAAU_0549	2.147e-214	696.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,36DR6@31979|Clostridiaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
ZZS2_k127_1890701_43	886293.Sinac_3193	8.638e-20	99.0	2E6AH@1|root,330YD@2|Bacteria,2J11U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_14	1396418.BATQ01000058_gene90	9.985e-116	379.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ZZS2_k127_1890701_52	478741.JAFS01000002_gene431	1.855e-09	64.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia,37H09@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
ZZS2_k127_1890701_35	497964.CfE428DRAFT_6673	1.255e-34	136.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS2_k127_1890701_22	1144310.PMI07_005783	6.499e-79	282.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,4BGGI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
ZZS2_k127_1890701_18	1396141.BATP01000039_gene1469	5.148e-92	331.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_1890701_12	240016.ABIZ01000001_gene3280	1.64e-119	400.0	COG3828@1|root,COG3828@2|Bacteria,46X17@74201|Verrucomicrobia,2IU7H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_1890701_7	1242864.D187_007612	1.276e-217	683.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM isocitrate isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS2_k127_1890701_49	1156937.MFUM_680018	2.916e-12	71.0	COG0828@1|root,COG0828@2|Bacteria,46WP6@74201|Verrucomicrobia,37HBT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ZZS2_k127_1890701_21	497964.CfE428DRAFT_1667	2.941e-79	276.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_1890701_38	1156937.MFUM_1010095	1.059e-30	135.0	COG0392@1|root,COG0392@2|Bacteria,46T31@74201|Verrucomicrobia,37GPN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS2_k127_1890701_17	314278.NB231_00265	7.575e-98	326.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria,1X0JC@135613|Chromatiales	135613|Chromatiales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
ZZS2_k127_1890701_39	933262.AXAM01000005_gene2530	4.38e-30	123.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria,2MJVR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ZZS2_k127_1890701_5	269799.Gmet_1676	8.501e-224	702.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
ZZS2_k127_1890701_9	331113.SNE_A13560	5.541e-213	672.0	COG0578@1|root,COG0578@2|Bacteria,2JG33@204428|Chlamydiae	204428|Chlamydiae	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
ZZS2_k127_1890701_54	66869.JNXG01000002_gene6614	0.0007126	53.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,41BTH@629295|Streptomyces griseus group	201174|Actinobacteria	G	Carbohydrate binding domain (family 11)	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_11,Calx-beta,Glyco_hydro_3,Glyco_hydro_3_C
ZZS2_k127_1890701_37	886293.Sinac_2696	1.278e-31	144.0	COG3420@1|root,COG3420@2|Bacteria,2J2MQ@203682|Planctomycetes	203682|Planctomycetes	P	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_1890701_50	1237149.C900_03068	1.51e-10	70.0	2CDET@1|root,2ZBN1@2|Bacteria,4NN6D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_0	583355.Caka_2960	0.0	1378.0	28HY3@1|root,2Z83I@2|Bacteria,46U77@74201|Verrucomicrobia,3K7PJ@414999|Opitutae	414999|Opitutae	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
ZZS2_k127_1890701_27	530564.Psta_2389	1.274e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_1890701_48	696747.NIES39_B01010	4.297e-13	80.0	COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria,1H81Z@1150|Oscillatoriales	1117|Cyanobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
ZZS2_k127_1890701_28	1454007.JAUG01000098_gene1475	3.291e-60	240.0	COG1361@1|root,COG2374@1|root,COG3121@1|root,COG3209@1|root,COG1361@2|Bacteria,COG2374@2|Bacteria,COG3121@2|Bacteria,COG3209@2|Bacteria,4NG16@976|Bacteroidetes,1ITFW@117747|Sphingobacteriia	976|Bacteroidetes	M	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11
ZZS2_k127_1890701_34	583355.Caka_2714	1.249e-36	151.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_51	530564.Psta_3937	1.116e-09	72.0	291K2@1|root,30VIH@2|Bacteria,2IZH0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_23	886293.Sinac_6514	2.539e-77	273.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
ZZS2_k127_1890701_47	1286632.P278_17170	6.813e-14	79.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ZZS2_k127_1890701_16	497964.CfE428DRAFT_0270	4.191e-100	331.0	COG0176@1|root,COG0176@2|Bacteria,46TNS@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM Transaldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
ZZS2_k127_1890701_24	497964.CfE428DRAFT_2552	2.145e-72	248.0	COG0241@1|root,COG0241@2|Bacteria,46T3Q@74201|Verrucomicrobia	74201|Verrucomicrobia	E	hydrolase, HAD-superfamily, subfamily IIIA	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
ZZS2_k127_1890701_13	497964.CfE428DRAFT_5722	1.86e-117	403.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
ZZS2_k127_1890701_45	1123242.JH636438_gene5783	5.479e-19	93.0	2EC9T@1|root,33685@2|Bacteria,2J40D@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_44	330214.NIDE3768	1.624e-19	93.0	COG0296@1|root,COG0296@2|Bacteria,3J0Y2@40117|Nitrospirae	40117|Nitrospirae	G	Alpha amylase, catalytic domain	-	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48
ZZS2_k127_1890701_19	530564.Psta_0855	2.672e-80	274.0	COG1082@1|root,COG1082@2|Bacteria,2J52H@203682|Planctomycetes	203682|Planctomycetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_1890701_2	1123508.JH636445_gene6725	2.937e-253	801.0	COG1621@1|root,COG1621@2|Bacteria,2IXNN@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 32	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
ZZS2_k127_1890701_1	1396141.BATP01000040_gene2167	0.0	1266.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
ZZS2_k127_1890701_15	883.DvMF_2329	6.391e-101	339.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,2MG4E@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_1890701_20	886293.Sinac_0726	1.59e-79	291.0	COG0613@1|root,COG0613@2|Bacteria,2J1VB@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_30	1210884.HG799465_gene11730	6.731e-46	188.0	COG0657@1|root,COG0657@2|Bacteria,2IXWJ@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
ZZS2_k127_1890701_32	1032480.MLP_33800	1.651e-44	179.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
ZZS2_k127_1890701_42	485917.Phep_1061	7.731e-24	118.0	COG1044@1|root,COG1044@2|Bacteria,4P2I7@976|Bacteroidetes,1IY65@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_40	1396141.BATP01000022_gene331	1.219e-26	127.0	COG5184@1|root,COG5184@2|Bacteria,46XQ3@74201|Verrucomicrobia,2IWCT@203494|Verrucomicrobiae	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
ZZS2_k127_1890701_31	926569.ANT_03070	1.018e-44	183.0	COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_53	452637.Oter_0313	2.996e-09	70.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,46Z5C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3
ZZS2_k127_1890701_41	452637.Oter_4612	6.988e-26	125.0	COG5549@1|root,COG5549@2|Bacteria,46UKP@74201|Verrucomicrobia,3KA3E@414999|Opitutae	2|Bacteria	O	Immunoglobulin I-set domain protein	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	CBM60,DUF4214,Glyco_hydro_16,HemolysinCabind,Peptidase_M10,Peptidase_M10_C,Reprolysin_4,W_rich_C
ZZS2_k127_1890701_6	1396141.BATP01000060_gene4727	4.841e-222	730.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_1890701_46	1041159.AZUW01000041_gene2575	8.599e-17	95.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2U6VS@28211|Alphaproteobacteria,4BM30@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaK	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_1890701_25	382464.ABSI01000011_gene2968	7.046e-69	259.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1890701_29	1123242.JH636435_gene2613	4.792e-54	198.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_1890701_3	886293.Sinac_0949	5.99e-251	799.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
ZZS2_k127_1890701_26	221288.JH992901_gene2043	2.124e-68	259.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JHSG@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
ZZS2_k127_1890701_10	1396141.BATP01000019_gene1735	2.004e-170	572.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,46XFS@74201|Verrucomicrobia,2IVSV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_1890701_4	234267.Acid_0830	6.341e-238	754.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
ZZS2_k127_1927686_12	1502724.FF80_00993	8.151e-51	189.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3N7U4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
ZZS2_k127_1927686_11	305700.B447_20945	2.165e-57	211.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
ZZS2_k127_1927686_18	195253.Syn6312_1865	3.369e-19	95.0	COG5661@1|root,COG5661@2|Bacteria,1G9TJ@1117|Cyanobacteria	1117|Cyanobacteria	O	Bacterial protein of unknown function (DUF922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
ZZS2_k127_1927686_6	886293.Sinac_1932	8.274e-96	345.0	COG2706@1|root,COG2706@2|Bacteria,2J55E@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_1927686_15	1210884.HG799464_gene11147	2.777e-38	157.0	COG0277@1|root,COG0277@2|Bacteria,2IYV5@203682|Planctomycetes	203682|Planctomycetes	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS2_k127_1927686_5	562970.Btus_2619	3.478e-108	365.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,278U1@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
ZZS2_k127_1927686_14	240016.ABIZ01000001_gene2939	3.559e-40	163.0	COG0491@1|root,COG0491@2|Bacteria,46S7X@74201|Verrucomicrobia,2IUKN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS2_k127_1927686_13	452637.Oter_4232	5.707e-47	178.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1927686_10	497964.CfE428DRAFT_6231	1.765e-57	220.0	COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,46S9G@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_1927686_2	278957.ABEA03000060_gene3064	9.79e-142	466.0	COG0421@1|root,COG0421@2|Bacteria,46Z5G@74201|Verrucomicrobia,3K91M@414999|Opitutae	414999|Opitutae	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1927686_17	589865.DaAHT2_0949	1.416e-19	92.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
ZZS2_k127_1927686_8	1379698.RBG1_1C00001G1509	3.06e-79	286.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SBBP
ZZS2_k127_1927686_4	794903.OPIT5_30480	2.017e-126	420.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
ZZS2_k127_1927686_9	497964.CfE428DRAFT_2483	4.451e-68	242.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_1927686_3	1340493.JNIF01000003_gene1929	2.6e-139	452.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	MA20_31690	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_1927686_20	2903.EOD37121	6.729e-10	66.0	2CZHE@1|root,2SAD3@2759|Eukaryota	2759|Eukaryota	S	Domain of unknown function (DUF3506)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3506,UVR
ZZS2_k127_1927686_21	278957.ABEA03000095_gene4619	2.225e-05	58.0	2B9GK@1|root,31PUX@2|Bacteria,46YCB@74201|Verrucomicrobia,3K9AR@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1927686_16	1396141.BATP01000009_gene2635	2.561e-26	114.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,2IUDV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
ZZS2_k127_1927686_0	497964.CfE428DRAFT_4667	1.757e-179	570.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
ZZS2_k127_1927686_1	452637.Oter_2571	1.339e-157	506.0	COG1092@1|root,COG1092@2|Bacteria,46UWW@74201|Verrucomicrobia,3K746@414999|Opitutae	414999|Opitutae	J	Met-10+ like-protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ZZS2_k127_1927686_19	1236976.JCM16418_4253	7.302e-17	96.0	COG1409@1|root,COG2041@1|root,COG3211@1|root,COG4733@1|root,COG1409@2|Bacteria,COG2041@2|Bacteria,COG3211@2|Bacteria,COG4733@2|Bacteria,1V7PQ@1239|Firmicutes,4IUC5@91061|Bacilli,277JF@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,SLH,fn3
ZZS2_k127_1927686_7	1396141.BATP01000003_gene4934	5.736e-85	316.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_1928468_4	497964.CfE428DRAFT_6513	4.615e-140	456.0	COG0577@1|root,COG0577@2|Bacteria,46SPG@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_1928468_8	497964.CfE428DRAFT_6512	1.677e-124	413.0	COG0577@1|root,COG0577@2|Bacteria,46SK8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_1928468_9	497964.CfE428DRAFT_6511	6.98e-102	336.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia	74201|Verrucomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_1928468_6	497964.CfE428DRAFT_6510	7.684e-128	422.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
ZZS2_k127_1928468_10	497964.CfE428DRAFT_0952	2.564e-94	316.0	COG1028@1|root,COG1028@2|Bacteria,46U52@74201|Verrucomicrobia	497964.CfE428DRAFT_0952|-	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1928468_0	886293.Sinac_1739	1.222e-260	843.0	COG2010@1|root,COG2010@2|Bacteria,2IXBU@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_1928468_2	497964.CfE428DRAFT_5489	5.449e-181	587.0	COG3119@1|root,COG3119@2|Bacteria,46UP0@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1928468_13	497964.CfE428DRAFT_3630	5.185e-63	229.0	COG2755@1|root,COG2755@2|Bacteria,46TWC@74201|Verrucomicrobia	74201|Verrucomicrobia	CEG	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Lipase_GDSL_2
ZZS2_k127_1928468_1	344747.PM8797T_24331	1.678e-198	657.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXWZ@203682|Planctomycetes	203682|Planctomycetes	C	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_1928468_3	234267.Acid_2416	2.705e-161	521.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
ZZS2_k127_1928468_17	573061.Clocel_1966	7.988e-28	131.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_1928468_7	425104.Ssed_1747	4.944e-126	431.0	COG0366@1|root,COG1409@1|root,COG0366@2|Bacteria,COG1409@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
ZZS2_k127_1928468_21	1121405.dsmv_0737	2.162e-08	68.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
ZZS2_k127_1928468_20	83406.HDN1F_11880	1.965e-10	74.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,Polysacc_lyase,RHS_repeat,SprB
ZZS2_k127_1928468_19	485916.Dtox_0887	1.945e-13	84.0	COG3409@1|root,COG3409@2|Bacteria,1UKDY@1239|Firmicutes,249W9@186801|Clostridia	186801|Clostridia	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4
ZZS2_k127_1928468_5	1396141.BATP01000040_gene2152	6.252e-139	449.0	COG0714@1|root,COG0714@2|Bacteria,46S9V@74201|Verrucomicrobia,2ITT6@203494|Verrucomicrobiae	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
ZZS2_k127_1928468_11	313628.LNTAR_03629	1.811e-89	304.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_1928468_15	1396141.BATP01000040_gene2150	4.271e-32	138.0	2BXEQ@1|root,33IN8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1928468_12	575540.Isop_3570	1.392e-76	268.0	COG2304@1|root,COG2304@2|Bacteria,2IXVS@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
ZZS2_k127_1928468_14	575540.Isop_3571	2.456e-62	227.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
ZZS2_k127_1928468_18	313628.LNTAR_03609	5.663e-18	93.0	2ECWJ@1|root,336TU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1928667_3	1121373.KB903623_gene2269	5.154e-106	346.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,47KMG@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	tolB3	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_1928667_4	1210884.HG799465_gene11911	6.392e-27	127.0	COG2319@1|root,COG3087@1|root,COG2319@2|Bacteria,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	ftsZ	-	-	ko:K01932,ko:K03531,ko:K03980	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01011,ko02000,ko02048,ko03036,ko04812	2.A.66.4	-	-	NYN,SPOR
ZZS2_k127_1928667_1	497964.CfE428DRAFT_2378	2.387e-230	720.0	COG4102@1|root,COG4102@2|Bacteria,46UP9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_1928667_2	497964.CfE428DRAFT_2806	1.408e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,46UZ4@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_1928667_5	1444712.BN1013_01574	3.908e-26	110.0	COG0184@1|root,COG0184@2|Bacteria,2JG4W@204428|Chlamydiae	204428|Chlamydiae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
ZZS2_k127_1928667_0	497964.CfE428DRAFT_3556	3.624e-280	882.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ZZS2_k127_193310_9	1121904.ARBP01000033_gene3213	3.274e-31	135.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,47UNS@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
ZZS2_k127_193310_10	261292.Nit79A3_2553	5.814e-27	118.0	2AZY1@1|root,31S7T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_193310_1	1380355.JNIJ01000023_gene2439	9.652e-181	571.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
ZZS2_k127_193310_7	886293.Sinac_7229	2.413e-32	142.0	arCOG10801@1|root,2Z9IC@2|Bacteria,2J23R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_193310_2	926554.KI912680_gene831	2.832e-122	438.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
ZZS2_k127_193310_5	449447.MAE_12430	9.371e-46	192.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
ZZS2_k127_193310_12	864051.BurJ1DRAFT_0895	4.23e-21	111.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
ZZS2_k127_193310_6	497964.CfE428DRAFT_4864	3.595e-43	168.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_193310_4	497964.CfE428DRAFT_0066	6.097e-68	255.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_193310_14	452637.Oter_0852	6.249e-07	63.0	COG1520@1|root,COG3386@1|root,COG1520@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin,DUF4347,DUF5122,He_PIG,I-set,Ig_3,Laminin_G_3,Peptidase_S8
ZZS2_k127_193310_8	498761.HM1_0137	7.23e-32	145.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
ZZS2_k127_193310_0	1396141.BATP01000060_gene4727	1.447e-217	719.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_193310_15	690850.Desaf_1376	0.0002263	49.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Big_5,LVIVD,Laminin_G_3,PKD
ZZS2_k127_193310_3	926562.Oweho_0501	2.309e-75	284.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia,2PB04@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
ZZS2_k127_193310_11	1267533.KB906735_gene4861	1.466e-24	118.0	COG0265@1|root,COG0265@2|Bacteria,3Y7GN@57723|Acidobacteria,2JM8V@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1947229_2	1392490.JHZX01000001_gene201	2.135e-51	213.0	COG1572@1|root,COG2931@1|root,COG3211@1|root,COG3540@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3211@2|Bacteria,COG3540@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia	976|Bacteroidetes	Q	twin-arginine translocation pathway signal protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_1947229_0	1396141.BATP01000034_gene4198	3.197e-268	921.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_1947229_3	1396141.BATP01000020_gene108	4.066e-09	72.0	COG2312@1|root,COG4870@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
ZZS2_k127_1947229_1	1347368.HG964405_gene6101	2.759e-61	245.0	COG3391@1|root,COG4632@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	tagL	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Flg_new,NAGPA,SLH
ZZS2_k127_1953885_9	316067.Geob_1640	2.233e-12	76.0	COG3861@1|root,COG3861@2|Bacteria,1QYWN@1224|Proteobacteria,43E8W@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
ZZS2_k127_1953885_0	1205680.CAKO01000008_gene4075	2.854e-68	244.0	COG1922@1|root,COG1922@2|Bacteria	2|Bacteria	M	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity	wecG	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
ZZS2_k127_1953885_3	1134912.AJTV01000010_gene651	5.537e-40	158.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_1953885_5	886293.Sinac_2760	4.383e-25	110.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_1953885_6	1123073.KB899242_gene1520	3.885e-21	104.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	4.4.1.3,5.3.3.19	ko:K16953,ko:K19547	ko00920,ko01130,map00920,map01130	M00787	R02574	RC00747,RC00748	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Arg_Hydrox,Cupin_1,Cupin_2
ZZS2_k127_1953885_7	1396141.BATP01000034_gene4198	7.899e-18	94.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_1953885_8	138119.DSY0542	4.013e-15	86.0	COG2247@1|root,COG4932@1|root,COG2247@2|Bacteria,COG4932@2|Bacteria,1UIDD@1239|Firmicutes,25EIH@186801|Clostridia,264RK@186807|Peptococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,fn3
ZZS2_k127_1953885_4	452637.Oter_2424	4.737e-38	155.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_1953885_1	886293.Sinac_4026	5.706e-62	219.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_1953885_2	1403819.BATR01000020_gene698	1.93e-61	241.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
ZZS2_k127_1971808_3	861299.J421_1753	6.214e-280	904.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_1971808_4	861299.J421_1753	1.193e-276	895.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_1971808_22	234267.Acid_4775	4.893e-27	121.0	COG1361@1|root,COG1649@1|root,COG1361@2|Bacteria,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Glyco_hydro_42M,PKD,SLH,WG_beta_rep
ZZS2_k127_1971808_1	1403819.BATR01000157_gene5228	0.0	1071.0	COG0542@1|root,COG0542@2|Bacteria,46S4S@74201|Verrucomicrobia,2ITN7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS2_k127_1971808_18	530564.Psta_3954	2.664e-64	231.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
ZZS2_k127_1971808_27	1270193.JARP01000001_gene2979	6.067e-09	70.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
ZZS2_k127_1971808_17	583355.Caka_1736	2.39e-64	253.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_1971808_28	926556.Echvi_2701	1.291e-05	60.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1971808_26	682795.AciX8_3725	3.99e-13	85.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
ZZS2_k127_1971808_7	583355.Caka_3109	3.257e-215	738.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
ZZS2_k127_1971808_23	1396141.BATP01000030_gene3719	9.338e-21	110.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
ZZS2_k127_1971808_25	583355.Caka_0935	1.542e-13	73.0	2EPKD@1|root,33H70@2|Bacteria,46WC0@74201|Verrucomicrobia,3K89T@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1971808_21	1267534.KB906754_gene3781	5.102e-39	148.0	COG0838@1|root,COG0838@2|Bacteria,3Y8B8@57723|Acidobacteria,2JN67@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
ZZS2_k127_1971808_19	452637.Oter_2164	2.444e-51	185.0	2DHFW@1|root,2ZZKM@2|Bacteria,46SNY@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	phyH	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1971808_14	344747.PM8797T_32255	9.554e-94	316.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
ZZS2_k127_1971808_16	425104.Ssed_3618	1.44e-69	252.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
ZZS2_k127_1971808_10	1210884.HG799465_gene12146	6.772e-132	437.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_1971808_8	240016.ABIZ01000001_gene2857	3.253e-205	644.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_1971808_20	278957.ABEA03000096_gene4628	4.261e-43	173.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,3K7YX@414999|Opitutae	414999|Opitutae	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
ZZS2_k127_1971808_13	383372.Rcas_3656	2.317e-98	332.0	COG0451@1|root,COG0451@2|Bacteria,2G7TT@200795|Chloroflexi	200795|Chloroflexi	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS2_k127_1971808_29	1267534.KB906754_gene3701	0.0001541	48.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,PAP2
ZZS2_k127_1971808_24	1298598.JCM21714_3761	5.878e-14	82.0	2DNUA@1|root,32Z63@2|Bacteria,1VEFD@1239|Firmicutes,4HYUD@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1971808_12	497964.CfE428DRAFT_0178	6.879e-100	334.0	COG1305@1|root,COG1305@2|Bacteria,46SMU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
ZZS2_k127_1971808_5	240016.ABIZ01000001_gene2652	5.491e-265	840.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,46TPA@74201|Verrucomicrobia,2IU1D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
ZZS2_k127_1971808_0	497321.C664_19086	0.0	1540.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
ZZS2_k127_1971808_9	1123508.JH636449_gene7450	9.1e-205	647.0	COG0205@1|root,COG0205@2|Bacteria,2IYE1@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	-	-	-	-	-	-	-	-	-	-	PFK
ZZS2_k127_1971808_11	1229172.JQFA01000004_gene848	3.793e-124	411.0	COG2307@1|root,COG2307@2|Bacteria,1G05F@1117|Cyanobacteria,1H8SU@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial domain of	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
ZZS2_k127_1971808_6	521674.Plim_1493	4.737e-233	736.0	COG2308@1|root,COG2308@2|Bacteria,2IXE6@203682|Planctomycetes	203682|Planctomycetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
ZZS2_k127_1971808_15	1121438.JNJA01000007_gene1645	1.279e-79	271.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MATW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
ZZS2_k127_1971808_2	497964.CfE428DRAFT_1614	5.08e-299	959.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
ZZS2_k127_2008732_1	497964.CfE428DRAFT_1982	4.056e-81	274.0	COG0330@1|root,COG0330@2|Bacteria,46U2V@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_2008732_0	443143.GM18_3859	1.811e-113	380.0	COG0061@1|root,COG0061@2|Bacteria,1NBI3@1224|Proteobacteria,42ZTT@68525|delta/epsilon subdivisions,2WV8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2008732_2	714943.Mucpa_0697	5.903e-53	192.0	COG3224@1|root,COG3224@2|Bacteria,4NMBB@976|Bacteroidetes,1IXFG@117747|Sphingobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
ZZS2_k127_2008732_3	797299.HALLA_12945	2.747e-12	70.0	COG0500@1|root,arCOG01791@2157|Archaea,2XW4Y@28890|Euryarchaeota,23VJQ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_202654_0	497964.CfE428DRAFT_1603	1.197e-153	491.0	COG0673@1|root,COG0673@2|Bacteria,46TYR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_202654_2	1122951.ATUE01000011_gene471	4.669e-66	229.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,3NIR5@468|Moraxellaceae	1236|Gammaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551	AIRC
ZZS2_k127_202654_1	1267535.KB906767_gene2202	4.308e-143	464.0	COG0026@1|root,COG0026@2|Bacteria,3Y3RI@57723|Acidobacteria,2JHQJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
ZZS2_k127_202654_3	481448.Minf_1859	5.974e-23	103.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
ZZS2_k127_2034061_1	1122222.AXWR01000034_gene153	2.812e-110	368.0	COG0167@1|root,COG0167@2|Bacteria,1WI2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS2_k127_2034061_0	240016.ABIZ01000001_gene326	5.026e-161	521.0	COG2317@1|root,COG2317@2|Bacteria,46TJB@74201|Verrucomicrobia,2IU0U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carboxypeptidase Taq (M32) metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M32
ZZS2_k127_2034061_2	497964.CfE428DRAFT_1642	2.278e-84	299.0	COG1028@1|root,COG1028@2|Bacteria,46VVI@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_2044336_1	765420.OSCT_3130	6.394e-116	412.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
ZZS2_k127_2044336_5	1156937.MFUM_40010	6.708e-15	79.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,37H6N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_2044336_3	1121374.KB891586_gene2767	4.474e-33	136.0	COG2010@1|root,COG2010@2|Bacteria,1N5P8@1224|Proteobacteria,1S9K3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_2044336_0	1094980.Mpsy_0698	2.222e-235	741.0	COG0058@1|root,arCOG01421@2157|Archaea,2XV8J@28890|Euryarchaeota,2NACZ@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
ZZS2_k127_2044336_2	1123257.AUFV01000021_gene2018	3.045e-106	349.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
ZZS2_k127_2061085_1	652103.Rpdx1_2782	3.949e-18	85.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,2UA4V@28211|Alphaproteobacteria,3JZ1P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_2061085_2	930166.CD58_07295	1.503e-09	59.0	COG0346@1|root,COG0346@2|Bacteria,1RH6K@1224|Proteobacteria,1S68V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutathione transferase	fosA	-	2.5.1.18	ko:K21253,ko:K21264,ko:K21265	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Glyoxalase
ZZS2_k127_2061085_0	251221.35211765	1.887e-143	487.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2086649_5	1396141.BATP01000030_gene3735	9.014e-95	316.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia,2IVKI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_2086649_6	1123508.JH636443_gene4872	3.14e-92	315.0	COG3828@1|root,COG3828@2|Bacteria,2IYPM@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_2086649_4	1210884.HG799465_gene11836	1.757e-109	361.0	COG3828@1|root,COG3828@2|Bacteria,2IYPM@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_2086649_1	344747.PM8797T_07447	1.507e-235	751.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
ZZS2_k127_2086649_7	338963.Pcar_0670	1.023e-74	258.0	COG0551@1|root,COG0551@2|Bacteria,1RCA8@1224|Proteobacteria,42R20@68525|delta/epsilon subdivisions,2WN67@28221|Deltaproteobacteria,43SKQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS2_k127_2086649_0	452637.Oter_3148	4.668e-261	833.0	COG1236@1|root,COG1793@1|root,COG1236@2|Bacteria,COG1793@2|Bacteria,46SCR@74201|Verrucomicrobia,3K8YZ@414999|Opitutae	414999|Opitutae	F	Zn-dependent metallo-hydrolase RNA specificity domain	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K07577,ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	RMMBL
ZZS2_k127_2086649_3	497964.CfE428DRAFT_4290	2.287e-169	544.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS2_k127_2086649_2	1396418.BATQ01000083_gene1164	8.448e-195	619.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,2ITND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,SIS
ZZS2_k127_2091256_9	278957.ABEA03000094_gene4644	3.532e-09	65.0	COG2165@1|root,COG2165@2|Bacteria,46Y3S@74201|Verrucomicrobia,3K8VV@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_2091256_4	1379270.AUXF01000001_gene1861	5.231e-74	286.0	COG1404@1|root,COG2247@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.4.24.3	ko:K01387,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Peptidase_S8,SLH
ZZS2_k127_2091256_5	1254432.SCE1572_41005	3.45e-59	237.0	COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,1RB92@1224|Proteobacteria,43CMY@68525|delta/epsilon subdivisions,2X7V4@28221|Deltaproteobacteria,2YXBK@29|Myxococcales	28221|Deltaproteobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_2091256_3	1210884.HG799464_gene11107	5.619e-105	358.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_2091256_8	331678.Cphamn1_0275	5.784e-22	103.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
ZZS2_k127_2091256_2	1210884.HG799469_gene14163	4.171e-109	368.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_2091256_0	1121935.AQXX01000122_gene5617	0.0	1045.0	COG0823@1|root,COG0823@2|Bacteria,1R4CN@1224|Proteobacteria,1S0NH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_2091256_7	936455.KI421499_gene372	2.381e-28	119.0	COG3801@1|root,COG3801@2|Bacteria,1REJV@1224|Proteobacteria,2U8BB@28211|Alphaproteobacteria,3JYZ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
ZZS2_k127_2091256_1	344747.PM8797T_15161	1.347e-143	468.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_2110377_16	1123253.AUBD01000014_gene870	3.469e-41	156.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1X6P3@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
ZZS2_k127_2110377_5	497964.CfE428DRAFT_4932	1.504e-127	418.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS2_k127_2110377_7	452637.Oter_1490	7.507e-86	288.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
ZZS2_k127_2110377_6	452637.Oter_1491	2.143e-106	359.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS2_k127_2110377_3	497964.CfE428DRAFT_0467	4.903e-144	468.0	COG1520@1|root,COG1520@2|Bacteria,46U5M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_2110377_11	452637.Oter_4241	2.06e-62	227.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,3K8EP@414999|Opitutae	414999|Opitutae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
ZZS2_k127_2110377_20	331678.Cphamn1_0596	1.436e-14	77.0	COG1826@1|root,COG1826@2|Bacteria,1FE6Y@1090|Chlorobi	1090|Chlorobi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS2_k127_2110377_21	1237149.C900_04710	5.738e-14	73.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS2_k127_2110377_17	1156937.MFUM_970047	1.341e-25	114.0	COG2885@1|root,COG2885@2|Bacteria,46T4D@74201|Verrucomicrobia,37GNQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
ZZS2_k127_2110377_10	497964.CfE428DRAFT_5284	2.961e-65	241.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,46SSK@74201|Verrucomicrobia	74201|Verrucomicrobia	U	WD40-like Beta Propeller Repeat	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
ZZS2_k127_2110377_22	251229.Chro_2443	0.0009931	50.0	COG0810@1|root,COG0810@2|Bacteria,1GQMS@1117|Cyanobacteria,3VJZY@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Gram-negative bacterial tonB protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	RDD,TonB_2
ZZS2_k127_2110377_19	497964.CfE428DRAFT_5287	3.823e-21	98.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_2110377_12	497964.CfE428DRAFT_5288	1.092e-53	197.0	COG0811@1|root,COG0811@2|Bacteria,46V4I@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
ZZS2_k127_2110377_8	382464.ABSI01000013_gene1636	8.385e-75	263.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
ZZS2_k127_2110377_2	497964.CfE428DRAFT_6644	2.371e-240	761.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
ZZS2_k127_2110377_18	1210884.HG799468_gene13605	1.247e-24	108.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
ZZS2_k127_2110377_4	404380.Gbem_2406	6.923e-131	446.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
ZZS2_k127_2110377_13	314230.DSM3645_14140	1.325e-49	192.0	2DBQG@1|root,2ZADX@2|Bacteria,2IZGN@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_2110377_14	404589.Anae109_0460	4.696e-43	172.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Gp58
ZZS2_k127_2110377_9	1210884.HG799474_gene15102	4.836e-67	249.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_2110377_0	1403819.BATR01000183_gene6345	6.569e-313	988.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,HEAT_2,PmoA,ThuA
ZZS2_k127_2110377_1	497964.CfE428DRAFT_0155	1.24e-276	860.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
ZZS2_k127_2125769_3	1396141.BATP01000005_gene6002	2.451e-88	306.0	COG2931@1|root,COG2931@2|Bacteria,46UDY@74201|Verrucomicrobia,2IWGN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2125769_9	1396141.BATP01000060_gene4588	5.176e-36	144.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_2125769_11	1403819.BATR01000002_gene98	2.586e-27	130.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
ZZS2_k127_2125769_4	1121481.AUAS01000011_gene4944	8.734e-73	273.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
ZZS2_k127_2125769_5	794903.OPIT5_26495	1.889e-72	252.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Phosphoglycerate mutase family	phoE	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ZZS2_k127_2125769_1	306281.AJLK01000020_gene2981	1.688e-149	492.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
ZZS2_k127_2125769_12	357808.RoseRS_0634	1.587e-07	64.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,PT-HINT,RHS_repeat
ZZS2_k127_2125769_0	452637.Oter_4175	2.444e-163	546.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_2125769_7	452637.Oter_4174	1.342e-54	201.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_2125769_10	1198452.Jab_1c17570	1.811e-35	143.0	2DP2V@1|root,330AH@2|Bacteria,1R3EE@1224|Proteobacteria,2WFSH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
ZZS2_k127_2125769_6	452637.Oter_4174	6.433e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_2125769_2	886293.Sinac_3618	2.547e-149	512.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_2125769_8	1207063.P24_07061	5.369e-46	175.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,2UCG6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
ZZS2_k127_2127412_31	383372.Rcas_0423	1.113e-07	64.0	COG3266@1|root,COG3266@2|Bacteria,2G8YE@200795|Chloroflexi,37830@32061|Chloroflexia	32061|Chloroflexia	S	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
ZZS2_k127_2127412_29	1123242.JH636434_gene4451	1.528e-11	72.0	COG3378@1|root,COG3598@1|root,COG4983@1|root,COG3378@2|Bacteria,COG3598@2|Bacteria,COG4983@2|Bacteria	2|Bacteria	L	Phage plasmid primase, P4 family domain protein	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	AAA_25,D5_N,Helicase_C,Pox_D5,PriCT_2,Prim-Pol,SNF2_N
ZZS2_k127_2127412_23	497964.CfE428DRAFT_1374	1.61e-50	193.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
ZZS2_k127_2127412_32	1150469.RSPPHO_02781	0.0002294	44.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2127412_27	661478.OP10G_0404	1.779e-16	88.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_2127412_2	240016.ABIZ01000001_gene4810	2.175e-244	775.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_2127412_12	243090.RB8482	4.073e-116	383.0	COG0688@1|root,COG0688@2|Bacteria,2J4CF@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
ZZS2_k127_2127412_4	234267.Acid_7180	4.715e-200	645.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria	57723|Acidobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
ZZS2_k127_2127412_18	452637.Oter_2549	1.814e-79	273.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
ZZS2_k127_2127412_13	754477.Q7C_1812	1.193e-114	375.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS2_k127_2127412_6	671143.DAMO_1101	6.987e-174	562.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_2127412_5	671143.DAMO_1102	3.172e-175	578.0	COG4590@1|root,COG4590@2|Bacteria,2NS4H@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_2127412_10	247490.KSU1_B0329	1.894e-121	398.0	COG0226@1|root,COG0226@2|Bacteria,2IYX0@203682|Planctomycetes	203682|Planctomycetes	P	COG0226 ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
ZZS2_k127_2127412_28	1207058.L53_09815	3.419e-13	82.0	2DSGQ@1|root,33G29@2|Bacteria,1Q8Z9@1224|Proteobacteria,2V7BM@28211|Alphaproteobacteria,43ZIV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
ZZS2_k127_2127412_20	1121405.dsmv_0221	1.211e-59	217.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,42S1K@68525|delta/epsilon subdivisions,2WP14@28221|Deltaproteobacteria,2MK1H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
ZZS2_k127_2127412_14	497964.CfE428DRAFT_3386	2.016e-103	343.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
ZZS2_k127_2127412_24	278957.ABEA03000060_gene3153	1.654e-32	143.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia,3K81M@414999|Opitutae	414999|Opitutae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_2127412_15	118173.KB235914_gene505	1.159e-102	343.0	COG2041@1|root,COG2041@2|Bacteria,1G169@1117|Cyanobacteria,1H9HS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
ZZS2_k127_2127412_3	886293.Sinac_5711	2.163e-215	682.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ7@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2127412_1	886293.Sinac_5710	2.811e-269	854.0	COG2010@1|root,COG2010@2|Bacteria,2IXJK@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2127412_0	497964.CfE428DRAFT_4145	5.867e-284	898.0	COG2133@1|root,COG2133@2|Bacteria,46UJH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
ZZS2_k127_2127412_9	886293.Sinac_5868	7.359e-126	414.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS2_k127_2127412_21	1123508.JH636444_gene5205	1.43e-56	209.0	COG4099@1|root,COG4099@2|Bacteria,2IZFN@203682|Planctomycetes	203682|Planctomycetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_2127412_7	497964.CfE428DRAFT_4132	6.003e-167	539.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_2127412_22	1453503.AU05_13500	1.235e-51	190.0	COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,1S59I@1236|Gammaproteobacteria,1YGN1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2127412_11	1396418.BATQ01000133_gene3999	6.94e-117	391.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_2127412_16	240016.ABIZ01000001_gene5475	5.321e-102	342.0	COG0647@1|root,COG0647@2|Bacteria,46WSA@74201|Verrucomicrobia,2IVSX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
ZZS2_k127_2127412_17	452637.Oter_2737	1.087e-91	314.0	COG0787@1|root,COG0787@2|Bacteria,46UBN@74201|Verrucomicrobia,3K796@414999|Opitutae	414999|Opitutae	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
ZZS2_k127_2127412_26	1485544.JQKP01000002_gene1648	2.282e-18	93.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,44VJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
ZZS2_k127_2127412_25	13035.Dacsa_2383	4.039e-25	109.0	COG0802@1|root,COG0802@2|Bacteria,1G6ZV@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised P-loop hydrolase UPF0079	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
ZZS2_k127_2127412_19	497964.CfE428DRAFT_3691	1.17e-74	261.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS2_k127_2127412_30	1280698.AUJS01000032_gene2015	1.579e-08	65.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia,27VGV@189330|Dorea	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS2_k127_2127412_8	1123242.JH636436_gene23	1.167e-156	522.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_2151080_2	1121413.JMKT01000003_gene165	2.625e-49	182.0	COG2071@1|root,COG2071@2|Bacteria,1MZVA@1224|Proteobacteria,42R3F@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	glutamine amidotransferase	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
ZZS2_k127_2151080_3	1122182.KB903814_gene3095	2.406e-39	153.0	COG0494@1|root,COG0494@2|Bacteria,2IKMP@201174|Actinobacteria	201174|Actinobacteria	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
ZZS2_k127_2151080_0	118166.JH976537_gene4475	2.774e-189	599.0	COG0399@1|root,COG0399@2|Bacteria,1G36Q@1117|Cyanobacteria,1H7A2@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_2151080_1	118166.JH976537_gene4465	7.41e-66	237.0	COG1208@1|root,COG1208@2|Bacteria,1G128@1117|Cyanobacteria,1HG8R@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
ZZS2_k127_2151080_5	452637.Oter_0387	4.685e-22	99.0	COG1344@1|root,COG1344@2|Bacteria,46UN2@74201|Verrucomicrobia,3K864@414999|Opitutae	414999|Opitutae	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
ZZS2_k127_2151080_7	243090.RB8149	5.727e-13	72.0	COG1551@1|root,COG1551@2|Bacteria,2J0QX@203682|Planctomycetes	203682|Planctomycetes	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	-	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
ZZS2_k127_2151080_6	744872.Spica_1117	8.286e-20	94.0	COG1699@1|root,COG1699@2|Bacteria,2J7ZU@203691|Spirochaetes	203691|Spirochaetes	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
ZZS2_k127_2151080_4	696281.Desru_1342	1.8e-37	143.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
ZZS2_k127_2159035_1	1158607.UAU_03667	3.939e-16	82.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,4AZTQ@81852|Enterococcaceae	91061|Bacilli	IQ	KR domain	-	-	1.3.1.28	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R01505	RC00534	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
ZZS2_k127_2159035_2	243090.RB8149	6.319e-11	66.0	COG1551@1|root,COG1551@2|Bacteria,2J0QX@203682|Planctomycetes	203682|Planctomycetes	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	-	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
ZZS2_k127_2159035_3	794903.OPIT5_24985	2.289e-05	54.0	2FIUS@1|root,34AK6@2|Bacteria,46WE9@74201|Verrucomicrobia,3K8CJ@414999|Opitutae	414999|Opitutae	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
ZZS2_k127_2159035_0	794903.OPIT5_24930	8.266e-66	234.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia,3K7F7@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_216469_2	497964.CfE428DRAFT_4603	4.778e-47	174.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
ZZS2_k127_216469_0	1396418.BATQ01000127_gene2548	1.486e-170	546.0	COG0247@1|root,COG0247@2|Bacteria,46SAS@74201|Verrucomicrobia,2IUWH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
ZZS2_k127_216469_1	497964.CfE428DRAFT_1451	4.928e-125	413.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_21753_15	367737.Abu_1416	4.766e-07	61.0	COG3137@1|root,COG3137@2|Bacteria,1PWI2@1224|Proteobacteria,42W3Z@68525|delta/epsilon subdivisions,2YQX2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
ZZS2_k127_21753_1	1187851.A33M_3475	3.112e-251	784.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2TRUJ@28211|Alphaproteobacteria,3FDI8@34008|Rhodovulum	28211|Alphaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS2_k127_21753_0	886293.Sinac_6140	7.816e-302	955.0	COG2010@1|root,COG2010@2|Bacteria,2IXBU@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_21753_8	344747.PM8797T_16735	3.977e-109	381.0	COG0501@1|root,COG0501@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_21753_14	996637.SGM_0747	3.309e-23	100.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
ZZS2_k127_21753_16	536019.Mesop_0526	0.0001622	52.0	2DR1U@1|root,339TE@2|Bacteria,1NWT6@1224|Proteobacteria,2USV2@28211|Alphaproteobacteria,43QRD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_21753_2	595460.RRSWK_00425	2.708e-181	580.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_21753_10	382464.ABSI01000005_gene1083	6.09e-91	310.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ZZS2_k127_21753_9	595460.RRSWK_00423	2.356e-98	331.0	COG1172@1|root,COG1172@2|Bacteria,2IZWQ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K10559,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
ZZS2_k127_21753_6	215803.DB30_6962	2.22e-121	398.0	COG1879@1|root,COG1879@2|Bacteria,1MXJS@1224|Proteobacteria,42W3I@68525|delta/epsilon subdivisions,2X6G0@28221|Deltaproteobacteria,2YX15@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein-like domain	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS2_k127_21753_7	452637.Oter_1728	4.979e-110	373.0	COG0642@1|root,COG2205@2|Bacteria,46TKR@74201|Verrucomicrobia,3K7YS@414999|Opitutae	452637.Oter_1728|-	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_21753_12	1121396.KB893024_gene3908	1.875e-79	274.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MJ2V@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_21753_3	452637.Oter_1726	1.629e-166	541.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_21753_5	452637.Oter_3491	1.794e-123	438.0	COG2911@1|root,COG2911@2|Bacteria,46UPJ@74201|Verrucomicrobia,3K7BC@414999|Opitutae	414999|Opitutae	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
ZZS2_k127_21753_4	452637.Oter_3490	5.935e-130	441.0	COG4775@1|root,COG4775@2|Bacteria,46TW0@74201|Verrucomicrobia,3K7BR@414999|Opitutae	414999|Opitutae	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
ZZS2_k127_21753_11	452637.Oter_0358	4.936e-86	320.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46YZC@74201|Verrucomicrobia,3K9WB@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_2176184_4	313603.FB2170_10111	4.683e-43	184.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_2176184_0	1396141.BATP01000043_gene1929	1.838e-266	905.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2176184_6	211114.JOEF01000045_gene5338	5.068e-08	68.0	COG3209@1|root,COG3209@2|Bacteria,2GP7Z@201174|Actinobacteria,4DXWA@85010|Pseudonocardiales	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PA14,RHS_repeat
ZZS2_k127_2176184_5	1396141.BATP01000042_gene1928	1.9e-32	149.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2176184_1	1210884.HG799464_gene11112	2.856e-196	618.0	COG4948@1|root,COG4948@2|Bacteria,2IXGQ@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase muconate lactonizing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_2176184_2	1123242.JH636434_gene5541	9.083e-94	325.0	COG2271@1|root,COG2271@2|Bacteria,2J1WN@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_2176184_3	426117.M446_2092	5.974e-78	280.0	COG4222@1|root,COG4625@1|root,COG4222@2|Bacteria,COG4625@2|Bacteria,1N2PM@1224|Proteobacteria,2TR8N@28211|Alphaproteobacteria,1JXNI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Phytase-like
ZZS2_k127_2199017_4	497964.CfE428DRAFT_5401	5.048e-80	287.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_2199017_6	1116369.KB890024_gene2472	6.47e-58	211.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS2_k127_2199017_3	497964.CfE428DRAFT_5400	1.563e-90	304.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_2199017_7	945713.IALB_1700	3.244e-32	142.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
ZZS2_k127_2199017_0	247490.KSU1_D1049	3.072e-196	627.0	COG1178@1|root,COG1178@2|Bacteria,2J51F@203682|Planctomycetes	203682|Planctomycetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
ZZS2_k127_2199017_5	41431.PCC8801_2149	2.303e-64	227.0	COG0639@1|root,COG0639@2|Bacteria,1G4GG@1117|Cyanobacteria,3KGME@43988|Cyanothece	1117|Cyanobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
ZZS2_k127_2199017_8	1114970.PSF113_1375	2.173e-31	131.0	COG0346@1|root,COG0346@2|Bacteria,1RH6K@1224|Proteobacteria,1S68V@1236|Gammaproteobacteria,1YQQD@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Glyoxalase-like domain	fosA	-	2.5.1.18	ko:K21253,ko:K21264,ko:K21265	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Glyoxalase
ZZS2_k127_2199017_2	1123277.KB893172_gene488	1.316e-106	352.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
ZZS2_k127_2199017_1	1396141.BATP01000020_gene58	9.792e-173	559.0	COG2010@1|root,COG2010@2|Bacteria,46TEX@74201|Verrucomicrobia,2ITZG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_2208046_30	452637.Oter_0714	5.566e-12	67.0	COG1595@1|root,COG1639@1|root,COG1595@2|Bacteria,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HDOD,Sigma70_r2,Sigma70_r4_2
ZZS2_k127_2208046_10	886293.Sinac_5628	3.894e-132	436.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,2IX68@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
ZZS2_k127_2208046_11	575540.Isop_1978	1.214e-131	439.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	203682|Planctomycetes	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
ZZS2_k127_2208046_12	1396141.BATP01000034_gene4199	1.232e-120	428.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Collagen,F5_F8_type_C,FIVAR,Glyco_hydro_43,Laminin_G_3,Metallophos
ZZS2_k127_2208046_9	497964.CfE428DRAFT_2851	2.332e-151	508.0	2F7XU@1|root,340BQ@2|Bacteria,46VS8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2208046_28	595460.RRSWK_04245	1.578e-28	132.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2208046_0	1123242.JH636436_gene23	0.0	1131.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_2208046_20	1049564.TevJSym_af00930	2.561e-66	244.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1J6BK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
ZZS2_k127_2208046_6	497964.CfE428DRAFT_1708	1.41e-162	523.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
ZZS2_k127_2208046_25	889378.Spiaf_2817	5.067e-33	136.0	COG0248@1|root,COG0248@2|Bacteria,2J5XU@203691|Spirochaetes	203691|Spirochaetes	FP	Ppx GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
ZZS2_k127_2208046_27	889378.Spiaf_2817	5.28e-31	132.0	COG0248@1|root,COG0248@2|Bacteria,2J5XU@203691|Spirochaetes	203691|Spirochaetes	FP	Ppx GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
ZZS2_k127_2208046_23	1463821.JOGR01000003_gene894	9.944e-43	168.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4EXWS@85014|Glycomycetales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
ZZS2_k127_2208046_19	344747.PM8797T_19091	4.637e-70	249.0	COG1940@1|root,COG1940@2|Bacteria,2IY6I@203682|Planctomycetes	203682|Planctomycetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_2208046_16	497964.CfE428DRAFT_6353	5.257e-81	277.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
ZZS2_k127_2208046_15	497964.CfE428DRAFT_6354	2.21e-93	312.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
ZZS2_k127_2208046_18	497964.CfE428DRAFT_6105	1.151e-76	267.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS2_k127_2208046_7	497964.CfE428DRAFT_2602	8.942e-160	518.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
ZZS2_k127_2208046_17	1379698.RBG1_1C00001G1752	2.678e-79	289.0	COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria	2|Bacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
ZZS2_k127_2208046_13	497964.CfE428DRAFT_4273	1.332e-113	374.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
ZZS2_k127_2208046_5	690850.Desaf_2604	2.219e-166	540.0	COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,431Z2@68525|delta/epsilon subdivisions,2WWQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
ZZS2_k127_2208046_2	452637.Oter_1810	3.232e-217	695.0	COG3590@1|root,COG3590@2|Bacteria,46UUX@74201|Verrucomicrobia	2|Bacteria	O	Peptidase family M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
ZZS2_k127_2208046_4	1396141.BATP01000040_gene2191	8.579e-202	637.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_2208046_21	1497679.EP56_04585	1.59e-60	216.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,26J8B@186820|Listeriaceae	91061|Bacilli	S	Zn-dependent protease	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
ZZS2_k127_2208046_8	1267535.KB906767_gene1479	1.015e-151	490.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
ZZS2_k127_2208046_14	1267535.KB906767_gene1478	1.153e-100	341.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS2_k127_2208046_26	530564.Psta_4263	1.803e-32	144.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	psrP1	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,Malectin
ZZS2_k127_2208046_31	1396141.BATP01000051_gene3371	3.145e-08	69.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	pnlA	-	4.2.2.10	ko:K01732,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	Flg_new,Pec_lyase_C,RicinB_lectin_2
ZZS2_k127_2208046_24	1121920.AUAU01000009_gene1881	4.269e-42	181.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_2208046_29	926550.CLDAP_29960	1.398e-21	113.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD
ZZS2_k127_2208046_3	1396141.BATP01000030_gene3719	1.542e-214	737.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
ZZS2_k127_2208046_22	1051632.TPY_0383	2.065e-45	175.0	COG2912@1|root,COG2912@2|Bacteria,1VXJ8@1239|Firmicutes,25294@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
ZZS2_k127_2208046_1	471852.Tcur_3603	2.269e-273	859.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4EGVM@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
ZZS2_k127_2208181_0	497964.CfE428DRAFT_6615	9.568e-235	734.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
ZZS2_k127_2208181_2	1198114.AciX9_2866	3.995e-30	128.0	2EGZK@1|root,33ARQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2208181_1	211165.AJLN01000098_gene5214	4.209e-131	430.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1JKCQ@1189|Stigonemataceae	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
ZZS2_k127_2231104_3	497964.CfE428DRAFT_1984	6.384e-140	451.0	COG3387@1|root,COG3387@2|Bacteria,46SD5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
ZZS2_k127_2231104_4	945713.IALB_1966	2.014e-78	274.0	COG0837@1|root,COG0837@2|Bacteria	2|Bacteria	G	glucokinase activity	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
ZZS2_k127_2231104_0	497964.CfE428DRAFT_6515	2.216e-292	959.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
ZZS2_k127_2231104_11	110663.KI911558_gene1982	1.79e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1G0BJ@1117|Cyanobacteria,1GZ50@1129|Synechococcus	1117|Cyanobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
ZZS2_k127_2231104_8	395493.BegalDRAFT_3253	3.307e-18	101.0	COG2931@1|root,COG3266@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,1QZXX@1224|Proteobacteria	1224|Proteobacteria	U	endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2231104_6	373994.Riv7116_1992	3.462e-27	130.0	COG1520@1|root,COG1520@2|Bacteria,1GHEB@1117|Cyanobacteria,1HKIG@1161|Nostocales	1117|Cyanobacteria	C	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114
ZZS2_k127_2231104_10	755178.Cyan10605_1021	8.627e-11	76.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria	1117|Cyanobacteria	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP
ZZS2_k127_2231104_7	1123508.JH636446_gene6209	1.553e-23	104.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	2|Bacteria	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2231104_2	886293.Sinac_7587	9.977e-147	476.0	COG4102@1|root,COG4102@2|Bacteria,2IY2D@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2231104_1	886293.Sinac_7588	2.474e-264	842.0	COG2010@1|root,COG2010@2|Bacteria,2IYM5@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2231104_9	240015.ACP_2836	1.612e-13	73.0	2DU51@1|root,33NYH@2|Bacteria	2|Bacteria	-	-	vapB39	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2231104_5	240015.ACP_2835	3.528e-43	165.0	COG1848@1|root,COG1848@2|Bacteria,3Y8JE@57723|Acidobacteria	57723|Acidobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	-
ZZS2_k127_2241566_14	679200.HMPREF9333_00914	6.599e-13	77.0	COG1277@1|root,COG1277@2|Bacteria,1V90F@1239|Firmicutes,25DFP@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
ZZS2_k127_2241566_2	497964.CfE428DRAFT_4319	5.322e-170	538.0	COG0667@1|root,COG0667@2|Bacteria,46SC7@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM aldo keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
ZZS2_k127_2241566_10	1131814.JAFO01000001_gene2573	2.265e-45	166.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
ZZS2_k127_2241566_13	382464.ABSI01000012_gene2231	1.082e-16	94.0	COG1404@1|root,COG1404@2|Bacteria,46UBH@74201|Verrucomicrobia,2IVTR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_2241566_6	1121468.AUBR01000016_gene2312	6.166e-71	252.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,42F3V@68295|Thermoanaerobacterales	186801|Clostridia	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
ZZS2_k127_2241566_1	443143.GM18_2774	1.65e-183	590.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
ZZS2_k127_2241566_12	644282.Deba_3052	8.651e-19	98.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02660,ko:K11525	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,EAL,GAF,GGDEF,HAMP,MCPsignal,PAS_3,PAS_4,PAS_7,dCache_1
ZZS2_k127_2241566_8	269797.Mbar_A3247	1.511e-50	192.0	COG0784@1|root,arCOG02349@1|root,arCOG02349@2157|Archaea,arCOG02386@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_2241566_11	583355.Caka_1363	1.47e-35	139.0	COG0745@1|root,COG0745@2|Bacteria,46W19@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_2241566_0	497964.CfE428DRAFT_6231	5.15e-208	666.0	COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,46S9G@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_2241566_5	596152.DesU5LDRAFT_0399	6.604e-98	344.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WMP9@28221|Deltaproteobacteria,2MB8A@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4
ZZS2_k127_2241566_9	1242864.D187_002317	1.623e-50	183.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_2241566_3	1444712.BN1013_01178	2.9e-135	445.0	COG0215@1|root,COG0215@2|Bacteria,2JFNB@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
ZZS2_k127_2241566_7	1396141.BATP01000025_gene914	4.62e-52	191.0	COG2353@1|root,COG2353@2|Bacteria,46XF3@74201|Verrucomicrobia,2IVQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS2_k127_2241566_4	886293.Sinac_5427	1.904e-103	340.0	COG3485@1|root,COG3485@2|Bacteria,2IYK6@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
ZZS2_k127_2251054_0	382464.ABSI01000007_gene4096	7.825e-32	138.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia,2IUNI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2265894_3	1396141.BATP01000003_gene4934	7.909e-164	572.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_2265894_9	794903.OPIT5_22660	3.346e-24	121.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2265894_12	1396141.BATP01000034_gene4198	3.32e-16	95.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_2265894_0	243090.RB544	1.729e-307	972.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2265894_1	243090.RB546	1.082e-235	738.0	COG3119@1|root,COG3119@2|Bacteria,2IXXZ@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2265894_7	1123242.JH636434_gene3172	1.856e-40	174.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2265894_4	497964.CfE428DRAFT_1804	1.49e-153	529.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
ZZS2_k127_2265894_6	497964.CfE428DRAFT_5731	1.769e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_2265894_8	1396141.BATP01000042_gene1928	3.969e-29	138.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2265894_10	1122925.KB895378_gene2567	1.873e-22	116.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_2265894_2	1396141.BATP01000043_gene1929	2.715e-183	645.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2265894_14	240016.ABIZ01000001_gene4912	0.0001886	55.0	COG2010@1|root,COG2010@2|Bacteria,46URX@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_2265894_13	886293.Sinac_3371	5.837e-10	73.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2265894_11	1961.JOAK01000040_gene4308	1.822e-20	108.0	COG1357@1|root,COG1409@1|root,COG2319@1|root,COG5635@1|root,COG1357@2|Bacteria,COG1409@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,TIR_2,Trypsin_2,WD40
ZZS2_k127_2265894_5	452637.Oter_1389	2.515e-153	528.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_2281647_5	251229.Chro_4406	1.933e-152	488.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,3VJ02@52604|Pleurocapsales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS2_k127_2281647_0	395961.Cyan7425_4369	0.0	1643.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,3KGSH@43988|Cyanothece	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
ZZS2_k127_2281647_19	330214.NIDE3863	2.096e-12	78.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS2_k127_2281647_11	330214.NIDE3859	2.85e-56	200.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS2_k127_2281647_8	1340493.JNIF01000004_gene137	3.259e-75	261.0	COG2823@1|root,COG2823@2|Bacteria,3Y7T6@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS2_k127_2281647_16	452637.Oter_4425	7.929e-19	92.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
ZZS2_k127_2281647_18	1123054.KB907719_gene2706	5.238e-16	85.0	COG2010@1|root,COG2010@2|Bacteria,1N5P8@1224|Proteobacteria,1S9K3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_2281647_6	478741.JAFS01000001_gene1364	1.015e-144	477.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,46YW3@74201|Verrucomicrobia,37G5X@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	AAA domain	gntK	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
ZZS2_k127_2281647_20	595460.RRSWK_00985	7.279e-05	50.0	COG1796@1|root,COG1796@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dpbF	-	3.1.11.5	ko:K02347,ko:K03581,ko:K04477	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,HHH_8
ZZS2_k127_2281647_12	330214.NIDE3803	3.932e-50	188.0	COG3647@1|root,COG3647@2|Bacteria	2|Bacteria	S	Membrane	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
ZZS2_k127_2281647_9	102125.Xen7305DRAFT_00020060	1.209e-69	271.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
ZZS2_k127_2281647_7	1121377.KB906411_gene455	5.37e-110	364.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	yfhM	-	-	ko:K22369	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abhydrolase_1
ZZS2_k127_2281647_15	1192034.CAP_3217	7.915e-24	111.0	COG5036@1|root,COG5036@2|Bacteria,1RG06@1224|Proteobacteria,42RP7@68525|delta/epsilon subdivisions,2WNHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
ZZS2_k127_2281647_17	497964.CfE428DRAFT_2343	3.079e-17	92.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
ZZS2_k127_2281647_13	1254432.SCE1572_13095	7.922e-42	158.0	COG3809@1|root,COG3809@2|Bacteria,1N33W@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
ZZS2_k127_2281647_3	946362.XP_004997743.1	9.325e-184	605.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
ZZS2_k127_2281647_4	269799.Gmet_2583	1.166e-161	534.0	COG2132@1|root,COG2132@2|Bacteria,1R9AF@1224|Proteobacteria,42YQG@68525|delta/epsilon subdivisions,2WTP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2
ZZS2_k127_2281647_14	247490.KSU1_A0074	1.281e-37	147.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS2_k127_2281647_2	926560.KE387023_gene1476	0.0	1127.0	COG3383@1|root,COG3383@2|Bacteria,1WJDD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
ZZS2_k127_2281647_1	452637.Oter_1454	0.0	1390.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_2281647_10	452637.Oter_1455	1.383e-63	229.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
ZZS2_k127_2283343_27	1304877.KI519399_gene2130	0.0004367	49.0	COG3011@1|root,COG3011@2|Bacteria,1N0YV@1224|Proteobacteria,2U5MD@28211|Alphaproteobacteria,3JY5Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
ZZS2_k127_2283343_21	313603.FB2170_10424	1.774e-12	77.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia,2PGP8@252356|Maribacter	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_2283343_0	521674.Plim_0192	2.505e-208	665.0	COG2866@1|root,COG2866@2|Bacteria,2J1EY@203682|Planctomycetes	203682|Planctomycetes	E	Zinc carboxypeptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_M14,Peptidase_S9
ZZS2_k127_2283343_19	215803.DB30_1527	2.875e-17	96.0	COG0708@1|root,COG4625@1|root,COG4932@1|root,COG0708@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3
ZZS2_k127_2283343_2	1304275.C41B8_12424	7.697e-130	423.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the class I fructose-bisphosphate aldolase family	alf1	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
ZZS2_k127_2283343_18	1453500.AT05_00860	9.001e-18	96.0	COG1449@1|root,COG3867@1|root,COG1449@2|Bacteria,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,Glyco_hydro_53,Glyco_hydro_57,He_PIG,RicinB_lectin_2,SLH
ZZS2_k127_2283343_11	452637.Oter_2047	2.671e-78	282.0	COG3867@1|root,COG3867@2|Bacteria,46VSS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycosyl hydrolase 53 domain protein	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
ZZS2_k127_2283343_20	471857.Svir_25890	5.033e-15	83.0	COG2020@1|root,COG2020@2|Bacteria,2IIDW@201174|Actinobacteria,4E55T@85010|Pseudonocardiales	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
ZZS2_k127_2283343_9	1122164.JHWF01000017_gene534	2.116e-89	301.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_2283343_13	1262914.BN533_00330	2.101e-59	216.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_2283343_14	1122165.AUHS01000023_gene241	8.043e-43	160.0	COG0236@1|root,COG0236@2|Bacteria,1NM9E@1224|Proteobacteria,1SINP@1236|Gammaproteobacteria,1JEJN@118969|Legionellales	118969|Legionellales	IQ	Phosphopantetheine attachment site	acpP_2	-	-	-	-	-	-	-	-	-	-	-	PP-binding
ZZS2_k127_2283343_15	272624.lpg0360	1.682e-30	131.0	COG0764@1|root,COG0764@2|Bacteria,1PCKD@1224|Proteobacteria,1SXNH@1236|Gammaproteobacteria,1JDAD@118969|Legionellales	118969|Legionellales	I	FabA-like domain	fabA	-	-	-	-	-	-	-	-	-	-	-	FabA
ZZS2_k127_2283343_1	1122164.JHWF01000017_gene538	7.702e-139	462.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JDCZ@118969|Legionellales	118969|Legionellales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS2_k127_2283343_5	1122169.AREN01000031_gene1458	6.719e-99	339.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JD6F@118969|Legionellales	118969|Legionellales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS2_k127_2283343_12	1408444.JHYC01000017_gene1966	6.887e-68	247.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RXSU@1236|Gammaproteobacteria,1JDJP@118969|Legionellales	118969|Legionellales	M	lipid A biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
ZZS2_k127_2283343_3	530564.Psta_0797	3.734e-118	397.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_2283343_7	880070.Cycma_0151	2.754e-96	324.0	COG2159@1|root,COG2159@2|Bacteria,4P15F@976|Bacteroidetes	976|Bacteroidetes	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
ZZS2_k127_2283343_4	880070.Cycma_0150	8.128e-116	382.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
ZZS2_k127_2283343_6	886293.Sinac_6933	3.566e-97	333.0	COG0657@1|root,COG0657@2|Bacteria,2IZ4H@203682|Planctomycetes	203682|Planctomycetes	G	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
ZZS2_k127_2283343_10	243090.RB9161	4.06e-88	312.0	COG0222@1|root,COG0222@2|Bacteria,2IZS6@203682|Planctomycetes	203682|Planctomycetes	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2283343_8	530564.Psta_4592	3.227e-93	327.0	COG4813@1|root,COG4813@2|Bacteria,2IZ2S@203682|Planctomycetes	203682|Planctomycetes	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_2283343_26	1396141.BATP01000022_gene476	0.0003341	44.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ZZS2_k127_2283343_24	1396141.BATP01000022_gene476	9.582e-09	61.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ZZS2_k127_2283343_16	1262449.CP6013_0770	2.103e-26	125.0	COG0457@1|root,COG3266@1|root,COG4676@1|root,COG4870@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,COG4676@2|Bacteria,COG4870@2|Bacteria,1VDA3@1239|Firmicutes	1239|Firmicutes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Flg_new,TPR_19
ZZS2_k127_2283343_22	1128427.KB904821_gene2444	1.127e-11	72.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,He_PIG
ZZS2_k127_2283343_23	886293.Sinac_0206	1.55e-10	73.0	COG4625@1|root,COG4625@2|Bacteria,2J0EF@203682|Planctomycetes	2|Bacteria	S	Bacterial Ig-like domain (group 3)	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,Big_3_5,Cadherin-like,Calx-beta,DUF4347,He_PIG,PATR,TIG,fn3
ZZS2_k127_2296057_47	33035.JPJF01000047_gene880	1.239e-13	82.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,3Y139@572511|Blautia	186801|Clostridia	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
ZZS2_k127_2296057_19	1167006.UWK_01269	4.533e-113	385.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,42MI1@68525|delta/epsilon subdivisions,2WP86@28221|Deltaproteobacteria,2MP3J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfatase	-	-	-	ko:K19353	ko00540,map00540	-	-	-	ko00000,ko00001,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
ZZS2_k127_2296057_6	1278073.MYSTI_07731	2.339e-225	736.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS2_k127_2296057_44	1123277.KB893232_gene1924	2.637e-25	125.0	COG3630@1|root,COG3630@2|Bacteria,4PKCP@976|Bacteroidetes,47Y7J@768503|Cytophagia	976|Bacteroidetes	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
ZZS2_k127_2296057_7	1396141.BATP01000043_gene1929	4.104e-208	705.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2296057_42	1396141.BATP01000042_gene1928	1.51e-33	152.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2296057_23	1340493.JNIF01000003_gene4018	8.487e-97	331.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH
ZZS2_k127_2296057_30	323261.Noc_2195	1.235e-64	230.0	28NSG@1|root,2ZBRE@2|Bacteria,1RFZV@1224|Proteobacteria,1SDKN@1236|Gammaproteobacteria,1X125@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
ZZS2_k127_2296057_2	452637.Oter_0618	1.208e-292	912.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
ZZS2_k127_2296057_51	452637.Oter_0107	4.935e-09	59.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
ZZS2_k127_2296057_54	411479.BACUNI_00828	4.626e-05	46.0	2BUU6@1|root,32Q5V@2|Bacteria,4PBMA@976|Bacteroidetes,2FZ7U@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2296057_32	794903.OPIT5_04525	1.337e-56	211.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS2_k127_2296057_43	497964.CfE428DRAFT_1216	2.584e-31	128.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
ZZS2_k127_2296057_24	497964.CfE428DRAFT_1215	9.533e-95	315.0	COG1100@1|root,COG1100@2|Bacteria,46VDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	Arf
ZZS2_k127_2296057_22	497964.CfE428DRAFT_1213	1.241e-99	336.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	DUF4388,HATPase_c,HTH_8,HisKA,Response_reg,SSF,Sigma54_activat
ZZS2_k127_2296057_52	364733.XP_007800575.1	2.222e-05	56.0	2DQSB@1|root,2S6CI@2759|Eukaryota,3A5I3@33154|Opisthokonta,3P43Y@4751|Fungi,3QX5Z@4890|Ascomycota,20IWP@147545|Eurotiomycetes,3MU4C@451870|Chaetothyriomycetidae	4751|Fungi	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
ZZS2_k127_2296057_25	497964.CfE428DRAFT_5932	6.297e-86	291.0	COG1131@1|root,COG1131@2|Bacteria,46TZ8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_2296057_15	497964.CfE428DRAFT_3562	3.382e-130	427.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_2296057_1	497964.CfE428DRAFT_2768	0.0	1053.0	COG5492@1|root,COG5492@2|Bacteria,46TTH@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_2296057_20	1116472.MGMO_115c00170	4.53e-109	377.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	3.4.14.5	ko:K01278,ko:K03561	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko04090,ko04147	1.A.30.2.1	-	-	DUF1735,DUF2341,Laminin_G_3,fn3
ZZS2_k127_2296057_10	794903.OPIT5_12380	1.406e-152	499.0	COG0621@1|root,COG0621@2|Bacteria,46S5U@74201|Verrucomicrobia,3K7CQ@414999|Opitutae	414999|Opitutae	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
ZZS2_k127_2296057_36	42256.RradSPS_2584	4.584e-44	166.0	COG1247@1|root,COG1247@2|Bacteria,2HU9F@201174|Actinobacteria,4CTVS@84995|Rubrobacteria	84995|Rubrobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
ZZS2_k127_2296057_37	903814.ELI_2067	6.855e-40	155.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ZZS2_k127_2296057_45	452637.Oter_3640	4.954e-24	110.0	COG1267@1|root,COG1267@2|Bacteria,46VNU@74201|Verrucomicrobia,3K86I@414999|Opitutae	414999|Opitutae	I	Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
ZZS2_k127_2296057_27	497964.CfE428DRAFT_4944	1.351e-71	248.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_2296057_29	321332.CYB_0857	1.133e-64	231.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria,1GZUC@1129|Synechococcus	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
ZZS2_k127_2296057_38	1121930.AQXG01000002_gene2148	1.626e-38	160.0	COG0860@1|root,COG4632@1|root,COG0860@2|Bacteria,COG4632@2|Bacteria,4NJF8@976|Bacteroidetes	976|Bacteroidetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
ZZS2_k127_2296057_8	234267.Acid_1146	7.871e-204	644.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2296057_3	234267.Acid_1145	1.594e-276	869.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_2296057_40	313628.LNTAR_04471	4.442e-34	134.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530,ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ZZS2_k127_2296057_17	478741.JAFS01000002_gene722	1.936e-115	386.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,37G1T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
ZZS2_k127_2296057_21	886293.Sinac_0400	6.311e-104	348.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2296057_50	1452536.JARE01000052_gene1721	2.13e-09	68.0	2EH4F@1|root,33AWE@2|Bacteria,2I6EJ@201174|Actinobacteria,4FTHX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2296057_9	497964.CfE428DRAFT_2154	1.275e-191	631.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
ZZS2_k127_2296057_26	247490.KSU1_C0526	2.881e-72	263.0	COG0265@1|root,COG0265@2|Bacteria,2IXAW@203682|Planctomycetes	203682|Planctomycetes	O	typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_2296057_11	709986.Deima_0518	7.766e-151	490.0	COG1092@1|root,COG1092@2|Bacteria,1WK2R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ZZS2_k127_2296057_13	634956.Geoth_2714	2.978e-135	442.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1WFFQ@129337|Geobacillus	91061|Bacilli	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
ZZS2_k127_2296057_12	382464.ABSI01000011_gene3117	4.377e-141	453.0	COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
ZZS2_k127_2296057_31	1227739.Hsw_3849	9.649e-60	220.0	COG4894@1|root,COG4894@2|Bacteria,4NK2I@976|Bacteroidetes,47VBX@768503|Cytophagia	976|Bacteroidetes	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	Scramblase
ZZS2_k127_2296057_16	1340493.JNIF01000004_gene301	1.518e-116	385.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
ZZS2_k127_2296057_41	227377.CBU_1820	1.284e-33	136.0	2BHMV@1|root,32BQM@2|Bacteria,1N9I1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2296057_55	1408445.JHXP01000014_gene1418	0.0004424	45.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RSC3@1236|Gammaproteobacteria,1JDAH@118969|Legionellales	118969|Legionellales	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
ZZS2_k127_2296057_33	1408445.JHXP01000014_gene1418	2.09e-51	190.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RSC3@1236|Gammaproteobacteria,1JDAH@118969|Legionellales	118969|Legionellales	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
ZZS2_k127_2296057_14	1123508.JH636440_gene2840	4.171e-134	442.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2296057_35	760192.Halhy_6806	5.889e-47	196.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
ZZS2_k127_2296057_0	1403819.BATR01000104_gene3505	0.0	1228.0	COG2133@1|root,COG3474@1|root,COG2133@2|Bacteria,COG3474@2|Bacteria,46UC5@74201|Verrucomicrobia,2IVI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_2296057_5	497964.CfE428DRAFT_0727	2.531e-241	758.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia	74201|Verrucomicrobia	C	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
ZZS2_k127_2296057_4	861299.J421_1753	2.593e-269	874.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_2296057_18	637905.SVI_1691	2.213e-113	384.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
ZZS2_k127_2296057_48	675812.VHA_001502	4.788e-13	82.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales	135623|Vibrionales	G	COG3325 Chitinase	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ
ZZS2_k127_2296057_49	324602.Caur_0720	7.766e-12	78.0	COG1572@1|root,COG1572@2|Bacteria,2GBJ4@200795|Chloroflexi,377QB@32061|Chloroflexia	32061|Chloroflexia	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
ZZS2_k127_2330835_1	771875.Ferpe_0574	6.788e-71	256.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
ZZS2_k127_2330835_2	1217705.F900_03481	3.253e-31	130.0	2EP04@1|root,33GKY@2|Bacteria,1NKWH@1224|Proteobacteria,1TE8T@1236|Gammaproteobacteria,3NKZU@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2330835_0	1123508.JH636439_gene1370	4.222e-183	594.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_2331855_2	1396141.BATP01000003_gene4934	3.419e-46	191.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_2331855_5	1248232.BANQ01000178_gene3298	9.875e-06	59.0	COG3209@1|root,COG3266@1|root,COG3343@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG3343@2|Bacteria,COG4932@2|Bacteria,1QZBF@1224|Proteobacteria,1T44G@1236|Gammaproteobacteria,1XWPY@135623|Vibrionales	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PA14,fn3
ZZS2_k127_2331855_3	326427.Cagg_3284	3.365e-18	100.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
ZZS2_k127_2331855_4	382464.ABSI01000010_gene3253	1.75e-14	88.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Kelch_1,Kelch_4,Kelch_6,SASA,SSF
ZZS2_k127_2331855_1	1144275.COCOR_03695	4.711e-69	265.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2331855_0	497964.CfE428DRAFT_0809	5.266e-194	623.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2360996_1	278957.ABEA03000040_gene3829	6.986e-161	514.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,3K7BN@414999|Opitutae	414999|Opitutae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
ZZS2_k127_2360996_2	497964.CfE428DRAFT_0322	1.572e-103	354.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
ZZS2_k127_2360996_4	497964.CfE428DRAFT_6605	1.242e-31	126.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
ZZS2_k127_2360996_5	1122604.JONR01000005_gene956	1.001e-27	117.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1X6XJ@135614|Xanthomonadales	135614|Xanthomonadales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
ZZS2_k127_2360996_3	497964.CfE428DRAFT_3293	2.639e-101	355.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C,EF-hand_5,Redoxin
ZZS2_k127_2360996_0	595460.RRSWK_00612	7.109e-207	657.0	COG0654@1|root,COG2755@1|root,COG0654@2|Bacteria,COG2755@2|Bacteria,2J0Y1@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_2360996_6	1123070.KB899248_gene6	1.915e-08	55.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS2_k127_2364758_0	926569.ANT_26260	2.117e-42	181.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2G87D@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_S8
ZZS2_k127_2378877_4	1210884.HG799475_gene15276	5.594e-07	63.0	COG1572@1|root,COG2304@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.14.18.1,3.4.24.40	ko:K00505,ko:K01406,ko:K07004	ko00350,ko00950,ko00965,ko01100,ko01110,ko01503,ko04916,map00350,map00950,map00965,map01100,map01110,map01503,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,VCBS,VWA_2
ZZS2_k127_2378877_3	935948.KE386494_gene695	1.672e-154	511.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
ZZS2_k127_2378877_6	926692.AZYG01000047_gene2700	0.0001669	51.0	COG5512@1|root,COG5512@2|Bacteria,1V9FF@1239|Firmicutes,24RDV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
ZZS2_k127_2378877_2	497964.CfE428DRAFT_5489	1.854e-176	565.0	COG3119@1|root,COG3119@2|Bacteria,46UP0@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2378877_1	497964.CfE428DRAFT_5126	1.998e-221	713.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2378877_0	1396418.BATQ01000064_gene1582	1.848e-230	728.0	COG1073@1|root,COG2755@1|root,COG1073@2|Bacteria,COG2755@2|Bacteria,46STE@74201|Verrucomicrobia,2IU0N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Peptidase_S9
ZZS2_k127_2378877_5	1487953.JMKF01000050_gene1922	2.848e-05	47.0	COG5485@1|root,COG5485@2|Bacteria,1GEBZ@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
ZZS2_k127_2388369_1	886293.Sinac_7009	2.991e-254	801.0	COG2010@1|root,COG2010@2|Bacteria,2IY6K@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2388369_3	234267.Acid_1108	6.498e-89	324.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria,3Y83C@57723|Acidobacteria	2|Bacteria	I	Ankyrin repeats (many copies)	-	-	3.5.1.81	ko:K06015,ko:K06867,ko:K06886	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,Prenyltrans,SQHop_cyclase_C,YkuD
ZZS2_k127_2388369_7	886293.Sinac_0433	4.229e-14	87.0	COG2010@1|root,COG2010@2|Bacteria,2IXBJ@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_2388369_8	314285.KT71_04495	1.216e-09	68.0	2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria,1SJE3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,VPEP
ZZS2_k127_2388369_0	1396141.BATP01000028_gene2287	0.0	1583.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria,46WKF@74201|Verrucomicrobia,2IVDI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,HEAT_2,Lipase_GDSL_2
ZZS2_k127_2388369_6	452637.Oter_0659	4.429e-26	119.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yprA	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS2_k127_2388369_5	1396141.BATP01000022_gene383	1.003e-29	128.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
ZZS2_k127_2388369_2	243090.RB5637	3.69e-95	321.0	COG3622@1|root,COG3622@2|Bacteria,2IY93@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_2388369_4	1396141.BATP01000042_gene1925	4.48e-48	173.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2403625_2	661478.OP10G_3689	1.051e-42	166.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_2403625_1	113395.AXAI01000015_gene538	5.035e-57	212.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,3JW83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
ZZS2_k127_2403625_0	234267.Acid_1949	1.357e-109	369.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,FG-GAP,VCBS
ZZS2_k127_2424598_9	215803.DB30_8307	1.266e-12	84.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
ZZS2_k127_2424598_7	102129.Lepto7375DRAFT_5860	1.24e-27	134.0	COG2304@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG4964@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG4964@2|Bacteria,1G54N@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the GSP D family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2424598_5	1121920.AUAU01000009_gene1881	6.204e-65	257.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_2424598_6	357808.RoseRS_3112	2.407e-51	212.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2424598_12	697282.Mettu_1098	1.142e-06	64.0	COG0726@1|root,COG2931@1|root,COG0726@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XFUS@135618|Methylococcales	135618|Methylococcales	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2424598_4	234267.Acid_4124	1e-81	313.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
ZZS2_k127_2424598_11	1961.JOAK01000016_gene5359	8.572e-10	75.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122
ZZS2_k127_2424598_3	1236542.BALM01000005_gene2574	1.45e-87	332.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2424598_0	498211.CJA_0127	6.218e-186	658.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
ZZS2_k127_2424598_8	1122931.AUAE01000012_gene2346	1.023e-22	111.0	COG2006@1|root,COG2006@2|Bacteria,4NM3M@976|Bacteroidetes,2FQJA@200643|Bacteroidia,22ZP1@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
ZZS2_k127_2424598_10	1173026.Glo7428_2794	7.033e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,1G07G@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
ZZS2_k127_2424598_13	1131269.AQVV01000094_gene1601	1.268e-06	61.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000094_gene1601|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2424598_14	523791.Kkor_1481	0.0004091	51.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales	135619|Oceanospirillales	S	colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
ZZS2_k127_2424598_1	478741.JAFS01000001_gene1963	3.049e-104	361.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,37GA0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
ZZS2_k127_2424598_2	240016.ABIZ01000001_gene2992	2.224e-102	344.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
ZZS2_k127_2436698_1	1191523.MROS_1318	5.358e-117	394.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS2_k127_2436698_8	329726.AM1_4632	3.193e-51	195.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
ZZS2_k127_2436698_7	251221.35213566	1.146e-52	210.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2436698_5	871968.DESME_15100	4.102e-69	261.0	COG1629@1|root,COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,COG4771@2|Bacteria,1V0RA@1239|Firmicutes,24AV7@186801|Clostridia,260Q2@186807|Peptococcaceae	186801|Clostridia	EM	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Lipase_GDSL_2,TIG
ZZS2_k127_2436698_14	278957.ABEA03000084_gene2355	2.318e-20	105.0	COG1305@1|root,COG1305@2|Bacteria,46TGE@74201|Verrucomicrobia,3K9QX@414999|Opitutae	414999|Opitutae	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
ZZS2_k127_2436698_3	502025.Hoch_3453	2.371e-103	383.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2436698_16	1341157.RF007C_03240	2.399e-10	76.0	COG5337@1|root,COG5337@2|Bacteria,1UZ0S@1239|Firmicutes,24UMA@186801|Clostridia,3WRYB@541000|Ruminococcaceae	186801|Clostridia	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
ZZS2_k127_2436698_9	583355.Caka_1736	2.616e-47	198.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2436698_12	865937.Gilli_1968	4.002e-38	168.0	COG1749@1|root,COG3291@1|root,COG5295@1|root,COG1749@2|Bacteria,COG3291@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1I57T@117743|Flavobacteriia	976|Bacteroidetes	UW	Pfam Polysaccharide lyase family 8, super-sandwich domain	-	-	4.2.2.20,4.2.2.21	ko:K08961	-	-	-	-	ko00000,ko01000	-	-	-	Beta_helix,Big_3_3,Lyase_8,Lyase_catalyt,M60-like_N,NosD,Peptidase_M60
ZZS2_k127_2436698_13	530564.Psta_3067	1.024e-20	110.0	COG2931@1|root,COG4625@1|root,COG2931@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,Big_3_5,DUF4347,He_PIG,HemolysinCabind,PATR,TIG
ZZS2_k127_2436698_17	1396141.BATP01000007_gene5656	8.497e-09	71.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2436698_0	497964.CfE428DRAFT_2151	2.011e-129	424.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS2_k127_2436698_11	1231336.L248_1168	2.935e-42	162.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
ZZS2_k127_2436698_10	382464.ABSI01000012_gene2250	1.169e-46	171.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
ZZS2_k127_2436698_15	452637.Oter_2716	1.817e-16	79.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia,3K8FH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2436698_6	663278.Ethha_2121	6.043e-58	210.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3WHAC@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_2436698_2	478741.JAFS01000001_gene1249	1.461e-106	353.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,37G5K@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
ZZS2_k127_2436698_4	794903.OPIT5_26485	4.645e-92	314.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,3K8ZD@414999|Opitutae	414999|Opitutae	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
ZZS2_k127_2448132_1	1123257.AUFV01000021_gene2018	3.354e-149	479.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
ZZS2_k127_2448132_0	1183438.GKIL_4354	2.564e-192	629.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_2448132_2	251221.35211765	4.419e-125	428.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2449430_14	1396141.BATP01000056_gene3139	3.02e-21	95.0	COG0236@1|root,COG0236@2|Bacteria,46TAW@74201|Verrucomicrobia,2IW9A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
ZZS2_k127_2449430_5	240016.ABIZ01000001_gene4536	2.221e-90	312.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2IVAU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_2449430_6	1396141.BATP01000021_gene175	4.423e-73	260.0	2BYFZ@1|root,2ZG3M@2|Bacteria,46T80@74201|Verrucomicrobia,2IVMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ketoacyl-synt
ZZS2_k127_2449430_2	1396418.BATQ01000049_gene331	2.509e-142	463.0	COG0304@1|root,COG0304@2|Bacteria,46SKK@74201|Verrucomicrobia,2IVA4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS2_k127_2449430_11	478741.JAFS01000001_gene2100	7.331e-40	151.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,37GT0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
ZZS2_k127_2449430_7	644966.Tmar_0895	1.239e-66	241.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
ZZS2_k127_2449430_15	243231.GSU1489	5.01e-14	87.0	COG1807@1|root,COG1807@2|Bacteria,1N8ZV@1224|Proteobacteria,42WB6@68525|delta/epsilon subdivisions,2WRTT@28221|Deltaproteobacteria,43TNH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
ZZS2_k127_2449430_8	489825.LYNGBM3L_43340	2.031e-58	220.0	2DBRK@1|root,2ZAME@2|Bacteria,1GAT0@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2449430_4	489825.LYNGBM3L_43350	2.466e-114	386.0	COG2837@1|root,COG2837@2|Bacteria,1G5Q6@1117|Cyanobacteria,1HHN4@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM Dyp-type peroxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Dyp_perox
ZZS2_k127_2449430_1	926550.CLDAP_17510	7.164e-173	565.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2449430_16	1396141.BATP01000029_gene2242	2.393e-10	72.0	COG1404@1|root,COG1404@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_2449430_9	1396141.BATP01000022_gene335	1.22e-53	211.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2449430_18	1089550.ATTH01000001_gene1987	2.76e-08	69.0	COG2866@1|root,COG2931@1|root,COG3291@1|root,COG2866@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,4NKIR@976|Bacteroidetes	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
ZZS2_k127_2449430_0	382464.ABSI01000010_gene3258	0.0	1111.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2449430_13	1396141.BATP01000007_gene5571	2.086e-21	112.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
ZZS2_k127_2449430_12	1265505.ATUG01000001_gene4678	3.369e-23	118.0	COG0584@1|root,COG1409@1|root,COG0584@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GDPD_2,Metallophos,Pur_ac_phosph_N
ZZS2_k127_2449430_17	794903.OPIT5_12590	5.657e-10	72.0	COG3250@1|root,COG3250@2|Bacteria,46YFF@74201|Verrucomicrobia,3K9GC@414999|Opitutae	414999|Opitutae	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ZZS2_k127_2449430_10	1282360.ABAC460_18290	3.291e-45	167.0	2C4H4@1|root,32R9Y@2|Bacteria,1N9DV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2449430_3	497964.CfE428DRAFT_5678	1.638e-120	392.0	COG1116@1|root,COG1116@2|Bacteria,46UXE@74201|Verrucomicrobia	74201|Verrucomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
ZZS2_k127_2451350_2	765420.OSCT_3130	9.622e-50	189.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
ZZS2_k127_2451350_0	1304275.C41B8_14525	2.6e-139	452.0	COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,1RRNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	vanA	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS2_k127_2451350_1	309807.SRU_0542	4.698e-81	278.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
ZZS2_k127_2457962_0	1123508.JH636442_gene4219	2.487e-255	807.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
ZZS2_k127_2460562_6	794903.OPIT5_03390	6.833e-22	95.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
ZZS2_k127_2460562_3	1095769.CAHF01000022_gene355	7.211e-51	184.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VTFT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
ZZS2_k127_2460562_0	886293.Sinac_0081	3.073e-214	670.0	COG4447@1|root,COG4447@2|Bacteria,2IXU6@203682|Planctomycetes	203682|Planctomycetes	L	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2460562_5	497964.CfE428DRAFT_3867	2.705e-41	154.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
ZZS2_k127_2460562_2	1210884.HG799465_gene12239	1.965e-97	324.0	COG0500@1|root,COG2226@2|Bacteria,2IYMY@203682|Planctomycetes	203682|Planctomycetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_2460562_1	1122182.KB903838_gene4056	3.13e-209	671.0	COG2133@1|root,COG2133@2|Bacteria,2HEMB@201174|Actinobacteria,4DA70@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PA14,PKD
ZZS2_k127_2460562_4	1007103.AFHW01000106_gene5214	1.324e-41	156.0	COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes,4HKXB@91061|Bacilli,26YMK@186822|Paenibacillaceae	91061|Bacilli	P	Small Multidrug Resistance protein	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
ZZS2_k127_2460562_7	1054213.HMPREF9946_05144	6.865e-18	89.0	COG3391@1|root,COG3391@2|Bacteria,1R3YF@1224|Proteobacteria,2TUFI@28211|Alphaproteobacteria,2JWEZ@204441|Rhodospirillales	204441|Rhodospirillales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2490799_11	794903.OPIT5_07180	4.713e-42	156.0	COG0745@1|root,COG0745@2|Bacteria,46VXW@74201|Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_2490799_2	1229172.JQFA01000004_gene524	2.938e-163	582.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,1H77Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,Response_reg
ZZS2_k127_2490799_5	497964.CfE428DRAFT_6231	2.892e-119	402.0	COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,46S9G@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_2490799_14	398767.Glov_2434	2.549e-28	119.0	COG0745@1|root,COG0745@2|Bacteria	398767.Glov_2434|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2490799_8	1121015.N789_01165	1.653e-54	200.0	2ASI4@1|root,31HYJ@2|Bacteria,1QFMX@1224|Proteobacteria,1TCXF@1236|Gammaproteobacteria,1X9UV@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2490799_10	316067.Geob_1719	2.99e-43	174.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
ZZS2_k127_2490799_12	1151127.KB906326_gene15	3.351e-38	145.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,1YTVH@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
ZZS2_k127_2490799_6	497964.CfE428DRAFT_4937	3.841e-117	388.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
ZZS2_k127_2490799_3	497964.CfE428DRAFT_4938	1.535e-125	413.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
ZZS2_k127_2490799_4	1403819.BATR01000134_gene4788	9.919e-122	401.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_2490799_7	344747.PM8797T_01124	1.577e-101	346.0	COG1680@1|root,COG1680@2|Bacteria,2IZG3@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_2490799_0	661478.OP10G_4771	1.722e-268	861.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
ZZS2_k127_2490799_1	861299.J421_6019	3.314e-183	585.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	2|Bacteria	E	Amino acid permease	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
ZZS2_k127_2490799_13	388467.A19Y_1747	1.175e-35	147.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Peptidase_S8,SdrD_B
ZZS2_k127_2490799_9	1173028.ANKO01000219_gene462	4.821e-53	190.0	COG0614@1|root,COG0614@2|Bacteria,1G1W1@1117|Cyanobacteria,1H7T1@1150|Oscillatoriales	1117|Cyanobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
ZZS2_k127_2518775_11	1449347.JQLN01000005_gene3688	3.921e-06	60.0	COG3469@1|root,COG3469@2|Bacteria,2GJH0@201174|Actinobacteria,2M1PC@2063|Kitasatospora	201174|Actinobacteria	G	Glycosyl hydrolases family 18	chiA	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_18,fn3
ZZS2_k127_2518775_9	794903.OPIT5_09090	1.627e-14	82.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.4.1.21	ko:K00703,ko:K07082	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	AAA_12,DUF559,PGA_cap,WG_beta_rep
ZZS2_k127_2518775_8	1123399.AQVE01000002_gene2329	1.856e-19	106.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,He_PIG,OmpA,OmpA_membrane,fn3
ZZS2_k127_2518775_12	261292.Nit79A3_2343	4.322e-06	61.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
ZZS2_k127_2518775_10	682795.AciX8_3725	8.976e-13	83.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
ZZS2_k127_2518775_14	1068980.ARVW01000001_gene7382	0.0001537	56.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DZS9@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
ZZS2_k127_2518775_13	1464048.JNZS01000022_gene2452	2.957e-05	59.0	COG3537@1|root,COG3757@1|root,COG3537@2|Bacteria,COG3757@2|Bacteria,2GKYM@201174|Actinobacteria,4DAT5@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
ZZS2_k127_2518775_7	1396141.BATP01000034_gene4167	1.294e-37	166.0	COG3266@1|root,COG4625@1|root,COG3266@2|Bacteria,COG4625@2|Bacteria,46WVI@74201|Verrucomicrobia,2IW5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
ZZS2_k127_2518775_0	861299.J421_1753	1.237e-278	899.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_2518775_3	1396418.BATQ01000019_gene5009	4.128e-155	507.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
ZZS2_k127_2518775_6	1458357.BG58_17400	7.8e-80	282.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,2VQQ2@28216|Betaproteobacteria,1K00V@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
ZZS2_k127_2518775_5	471854.Dfer_5616	1.079e-101	342.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,47NZQ@768503|Cytophagia	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
ZZS2_k127_2518775_4	518766.Rmar_1740	1.466e-121	404.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_2518775_2	382464.ABSI01000010_gene3621	2.389e-187	598.0	COG2960@1|root,COG2960@2|Bacteria,46UCE@74201|Verrucomicrobia,2IVAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_2518775_1	382464.ABSI01000010_gene3622	2.569e-269	854.0	COG0551@1|root,COG0551@2|Bacteria,46SJD@74201|Verrucomicrobia,2IVAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
ZZS2_k127_2567438_2	221288.JH992901_gene4063	6.219e-204	671.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
ZZS2_k127_2567438_0	1174528.JH992893_gene5951	0.0	2062.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
ZZS2_k127_2567438_4	1173028.ANKO01000086_gene2	8.171e-154	552.0	COG1020@1|root,COG3882@1|root,COG1020@2|Bacteria,COG3882@2|Bacteria,1G2GR@1117|Cyanobacteria,1HEN0@1150|Oscillatoriales	1117|Cyanobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	NIF,PP-binding
ZZS2_k127_2567438_5	306281.AJLK01000165_gene3916	1.765e-153	503.0	COG4615@1|root,COG4615@2|Bacteria,1G2TH@1117|Cyanobacteria,1JI6A@1189|Stigonemataceae	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2	-	-	ABC_membrane,ABC_tran
ZZS2_k127_2567438_3	1173026.Glo7428_1477	7.841e-181	588.0	COG1858@1|root,COG1858@2|Bacteria,1G358@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
ZZS2_k127_2567438_7	886293.Sinac_2842	6.446e-48	191.0	COG2091@1|root,COG2091@2|Bacteria,2J06Q@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
ZZS2_k127_2567438_1	1380391.JIAS01000001_gene2708	2.889e-243	792.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1NC2U@1224|Proteobacteria,2U484@28211|Alphaproteobacteria	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
ZZS2_k127_2567438_6	497964.CfE428DRAFT_6498	2.56e-141	459.0	COG4251@1|root,COG4251@2|Bacteria,46UYC@74201|Verrucomicrobia	2|Bacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
ZZS2_k127_2567557_10	937777.Deipe_3242	6.724e-105	358.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	-	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
ZZS2_k127_2567557_8	886293.Sinac_7120	4.763e-115	385.0	COG3386@1|root,COG3386@2|Bacteria,2IXCR@203682|Planctomycetes	203682|Planctomycetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS2_k127_2567557_0	1396141.BATP01000019_gene1642	2.675e-303	947.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_2567557_1	886293.Sinac_6697	6.374e-258	800.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2567557_3	886293.Sinac_2846	1.843e-164	532.0	COG4102@1|root,COG4102@2|Bacteria,2IX5I@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2567557_4	314230.DSM3645_26469	1.308e-155	513.0	COG2010@1|root,COG2010@2|Bacteria,2IXDH@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_2567557_15	1303518.CCALI_01330	5.371e-08	64.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
ZZS2_k127_2567557_5	497964.CfE428DRAFT_4318	3.69e-154	493.0	COG1063@1|root,COG1063@2|Bacteria,46TQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_2567557_2	452637.Oter_4045	5.629e-167	538.0	COG0165@1|root,COG0165@2|Bacteria,46UYU@74201|Verrucomicrobia,3K76F@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
ZZS2_k127_2567557_6	1156937.MFUM_990021	2.262e-151	496.0	COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,37FYI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Pyruvate kinase, alpha/beta domain	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
ZZS2_k127_2567557_7	1123508.JH636440_gene2936	2.949e-126	409.0	COG1335@1|root,COG1335@2|Bacteria,2IX7K@203682|Planctomycetes	203682|Planctomycetes	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase,ThuA
ZZS2_k127_2567557_14	903818.KI912269_gene261	4.879e-28	124.0	COG0755@1|root,COG0755@2|Bacteria,3Y3QF@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
ZZS2_k127_2567557_11	1232410.KI421412_gene411	2.771e-88	302.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
ZZS2_k127_2567557_13	1121468.AUBR01000020_gene2856	7.386e-53	201.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,42G48@68295|Thermoanaerobacterales	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15760	Porphobil_deam,Porphobil_deamC
ZZS2_k127_2567557_12	247490.KSU1_D0861	1.58e-82	293.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_2567557_9	237368.SCABRO_00906	4.455e-107	368.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_2586735_5	497964.CfE428DRAFT_5026	7.868e-41	167.0	2DXTF@1|root,346G5@2|Bacteria,46W16@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2586735_0	497964.CfE428DRAFT_4943	1.063e-240	784.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
ZZS2_k127_2586735_2	572477.Alvin_0231	3.681e-56	205.0	2E1E7@1|root,32WT9@2|Bacteria,1N6HI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2586735_6	1232410.KI421414_gene2854	3.207e-39	162.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria,43UP8@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_2586735_12	1396141.BATP01000022_gene329	2.953e-27	123.0	295XR@1|root,2ZT8M@2|Bacteria,46XS9@74201|Verrucomicrobia,2IWGG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2586735_7	589924.Ferp_0234	4.26e-37	159.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
ZZS2_k127_2586735_3	1123278.KB893427_gene1235	2.46e-50	201.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2586735_9	1396141.BATP01000022_gene331	1.062e-33	149.0	COG5184@1|root,COG5184@2|Bacteria,46XQ3@74201|Verrucomicrobia,2IWCT@203494|Verrucomicrobiae	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
ZZS2_k127_2586735_1	481448.Minf_0409	1.095e-98	336.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,37GF1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
ZZS2_k127_2586735_8	478741.JAFS01000001_gene1164	8.841e-37	151.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,37G0C@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	nosY	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
ZZS2_k127_2586735_4	583355.Caka_2319	1.906e-46	186.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,3K735@414999|Opitutae	414999|Opitutae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
ZZS2_k127_2586735_11	478741.JAFS01000001_gene1166	8.344e-28	130.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,37FXR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
ZZS2_k127_2615740_3	497964.CfE428DRAFT_5270	1.489e-80	271.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
ZZS2_k127_2615740_2	497964.CfE428DRAFT_0418	2.999e-87	299.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS2_k127_2615740_6	1396141.BATP01000022_gene383	3.766e-38	161.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
ZZS2_k127_2615740_9	1198114.AciX9_2226	2.498e-08	66.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
ZZS2_k127_2615740_5	243231.GSU0621	2.302e-57	214.0	COG1215@1|root,COG1215@2|Bacteria,1NFA4@1224|Proteobacteria,42WEV@68525|delta/epsilon subdivisions,2WS1J@28221|Deltaproteobacteria,43U0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
ZZS2_k127_2615740_7	880072.Desac_2421	4.339e-29	127.0	COG5523@1|root,COG5523@2|Bacteria,1RGXF@1224|Proteobacteria,42WIC@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
ZZS2_k127_2615740_8	452637.Oter_0732	2.453e-10	71.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
ZZS2_k127_2615740_10	1150599.MPHLEI_14996	3.546e-05	55.0	2EGCD@1|root,33A46@2|Bacteria,2IRHA@201174|Actinobacteria,23ARC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
ZZS2_k127_2615740_4	497964.CfE428DRAFT_2629	7.871e-72	255.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
ZZS2_k127_2615740_0	497964.CfE428DRAFT_4373	0.0	1130.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
ZZS2_k127_2615740_1	497964.CfE428DRAFT_4376	0.0	1037.0	COG0187@1|root,COG0187@2|Bacteria,46SDH@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
ZZS2_k127_2623402_1	497964.CfE428DRAFT_1800	2.279e-74	262.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
ZZS2_k127_2623402_0	583355.Caka_2762	9.393e-97	329.0	COG0524@1|root,COG0524@2|Bacteria,46TT7@74201|Verrucomicrobia,3K7V3@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS2_k127_2623402_2	497964.CfE428DRAFT_6518	5.613e-48	178.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ZZS2_k127_2627037_1	1267535.KB906767_gene4729	7.718e-195	635.0	COG0577@1|root,COG0577@2|Bacteria	1267535.KB906767_gene4729|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2627037_0	886293.Sinac_6627	1.179e-228	719.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4
ZZS2_k127_2627037_2	452637.Oter_1883	3.921e-188	615.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_2627037_3	861299.J421_0975	4.714e-82	280.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yhhY	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	2.3.1.128,2.3.1.178	ko:K03790,ko:K03825,ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_4
ZZS2_k127_2627037_4	204669.Acid345_0370	3.451e-13	73.0	COG0577@1|root,COG0577@2|Bacteria,3Y47F@57723|Acidobacteria,2JKGQ@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_2630800_4	748247.AZKH_2523	3.154e-50	185.0	COG3224@1|root,COG3224@2|Bacteria,1RFVR@1224|Proteobacteria	1224|Proteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
ZZS2_k127_2630800_0	243231.GSU0801	8.187e-137	449.0	COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria	1224|Proteobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
ZZS2_k127_2630800_1	1396141.BATP01000007_gene5711	1.937e-119	387.0	COG1335@1|root,COG1335@2|Bacteria,46ZJ7@74201|Verrucomicrobia,2IV6S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
ZZS2_k127_2630800_2	1403819.BATR01000053_gene1630	9.376e-102	337.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
ZZS2_k127_2630800_3	1396141.BATP01000025_gene912	2.81e-68	242.0	COG0583@1|root,COG0583@2|Bacteria,46ZKT@74201|Verrucomicrobia,2IVKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_2630800_5	118168.MC7420_2493	0.0001254	53.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
ZZS2_k127_2633085_2	1132442.KB889752_gene3695	2.388e-08	64.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus	91061|Bacilli	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
ZZS2_k127_2633085_0	240016.ABIZ01000001_gene1867	1.862e-239	759.0	COG0475@1|root,COG0475@2|Bacteria,46U4K@74201|Verrucomicrobia,2IV1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
ZZS2_k127_2633085_1	497964.CfE428DRAFT_4864	4.926e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2640380_5	591159.ACEZ01000002_gene6094	3.168e-10	74.0	COG0070@1|root,COG0070@2|Bacteria,2IB5W@201174|Actinobacteria	201174|Actinobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2640380_6	66869.JNXG01000011_gene228	1.157e-08	68.0	COG0070@1|root,COG0070@2|Bacteria,2IB5W@201174|Actinobacteria	201174|Actinobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2640380_4	1168034.FH5T_06865	2.86e-12	80.0	COG2304@1|root,COG3291@1|root,COG3391@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285,ko:K20274,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002,ko04147	-	-	-	VWA,VWA_2
ZZS2_k127_2640380_0	1144275.COCOR_05905	1.515e-116	399.0	COG2133@1|root,COG2133@2|Bacteria,1P3DX@1224|Proteobacteria	1224|Proteobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
ZZS2_k127_2640380_3	768671.ThimaDRAFT_0672	1.172e-28	126.0	COG3012@1|root,COG3012@2|Bacteria,1NAMR@1224|Proteobacteria,1SJ04@1236|Gammaproteobacteria,1X1XS@135613|Chromatiales	135613|Chromatiales	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
ZZS2_k127_2640380_1	948106.AWZT01000075_gene4888	6.515e-35	143.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,2VIW6@28216|Betaproteobacteria,1K2S8@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_2640380_2	865937.Gilli_1969	2.003e-31	140.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
ZZS2_k127_2696923_10	1463861.JNXE01000031_gene1287	3.751e-05	57.0	COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PA14
ZZS2_k127_2696923_11	554065.XP_005844650.1	4.949e-05	56.0	KOG4152@1|root,KOG4152@2759|Eukaryota	2759|Eukaryota	S	negative regulation of transcription, DNA-templated	-	GO:0005575,GO:0005623,GO:0005929,GO:0031514,GO:0042995,GO:0043226,GO:0044464,GO:0120025	-	ko:K10408,ko:K12562,ko:K20285	ko04144,ko04666,ko05016,map04144,map04666,map05016	-	-	-	ko00000,ko00001,ko04131,ko04812	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_5,Kelch_6
ZZS2_k127_2696923_0	861299.J421_0972	3.101e-275	860.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
ZZS2_k127_2696923_5	452637.Oter_1167	4.979e-101	335.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_2696923_9	1379698.RBG1_1C00001G0819	1.93e-20	96.0	COG4911@1|root,COG4911@2|Bacteria,2NQ4H@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
ZZS2_k127_2696923_8	497964.CfE428DRAFT_5668	4.663e-57	221.0	COG0457@1|root,COG0457@2|Bacteria,46V4J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_8
ZZS2_k127_2696923_2	497964.CfE428DRAFT_5666	1.7e-125	407.0	COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Histidine biosynthesis protein HisG domain	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
ZZS2_k127_2696923_6	497964.CfE428DRAFT_0066	7.509e-76	282.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_2696923_1	1396141.BATP01000030_gene3746	1.347e-219	692.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_2696923_4	886293.Sinac_6994	1.04e-103	346.0	COG1172@1|root,COG1172@2|Bacteria,2J3I0@203682|Planctomycetes	203682|Planctomycetes	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
ZZS2_k127_2696923_3	497964.CfE428DRAFT_3049	2.757e-117	398.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
ZZS2_k127_2696923_7	497964.CfE428DRAFT_3048	5.491e-67	235.0	COG1879@1|root,COG1879@2|Bacteria,46TWY@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS2_k127_2711649_0	1396141.BATP01000006_gene5432	6.676e-140	505.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
ZZS2_k127_2711649_3	869213.JCM21142_11	1.658e-10	77.0	COG1404@1|root,COG1404@2|Bacteria,4NTJJ@976|Bacteroidetes,47VMY@768503|Cytophagia	976|Bacteroidetes	O	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
ZZS2_k127_2711649_1	1396141.BATP01000034_gene4198	9.414e-75	289.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_2711649_4	240016.ABIZ01000001_gene5499	6.923e-08	68.0	COG2931@1|root,COG3203@1|root,COG3266@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3203@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,46VKK@74201|Verrucomicrobia,2IW2X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_2711649_2	929556.Solca_2621	9.324e-49	203.0	COG1520@1|root,COG1520@2|Bacteria,4PI1E@976|Bacteroidetes,1IYUU@117747|Sphingobacteriia	976|Bacteroidetes	Q	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2719003_3	1396141.BATP01000022_gene241	6e-77	275.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
ZZS2_k127_2719003_5	1296416.JACB01000001_gene3141	1.663e-22	103.0	COG1028@1|root,COG1028@2|Bacteria,4NHF5@976|Bacteroidetes,1I041@117743|Flavobacteriia,2YJAN@290174|Aquimarina	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS2_k127_2719003_8	313606.M23134_06635	6.278e-08	66.0	COG1028@1|root,COG1028@2|Bacteria,4NHF5@976|Bacteroidetes,47TEB@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS2_k127_2719003_1	1122138.AQUZ01000019_gene8188	3.613e-158	526.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
ZZS2_k127_2719003_2	1210884.HG799465_gene11380	4.729e-89	334.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_2719003_6	1254432.SCE1572_07440	2.34e-12	82.0	COG4935@1|root,COG4935@2|Bacteria,1QZT5@1224|Proteobacteria,42YUM@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2719003_9	1121920.AUAU01000009_gene1881	1.913e-05	54.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_2719003_7	497964.CfE428DRAFT_1074	1.345e-08	63.0	COG3420@1|root,COG3420@2|Bacteria,46T2V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
ZZS2_k127_2719003_0	595536.ADVE02000001_gene3060	4.307e-211	688.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,36Z5E@31993|Methylocystaceae	28211|Alphaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
ZZS2_k127_2719003_4	452637.Oter_4188	8.449e-44	163.0	COG0023@1|root,COG0023@2|Bacteria,46WEQ@74201|Verrucomicrobia,3K8EV@414999|Opitutae	414999|Opitutae	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
ZZS2_k127_2745190_4	497964.CfE428DRAFT_1669	1.477e-65	229.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
ZZS2_k127_2745190_2	240016.ABIZ01000001_gene54	3.876e-127	427.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
ZZS2_k127_2745190_3	595460.RRSWK_02103	1.445e-76	271.0	COG3618@1|root,COG3618@2|Bacteria,2IZ0A@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_2745190_1	1123508.JH636439_gene1230	8.114e-235	758.0	COG2133@1|root,COG2133@2|Bacteria,2IXS5@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
ZZS2_k127_2745190_0	478741.JAFS01000001_gene1300	7.042e-273	855.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,37GG7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
ZZS2_k127_2745190_5	886293.Sinac_6941	1.022e-18	90.0	COG0613@1|root,COG0613@2|Bacteria,2IX3G@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_277565_10	555779.Dthio_PD1485	6.915e-08	55.0	2EQIX@1|root,33I4Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
ZZS2_k127_277565_2	420324.KI912022_gene340	0.0	1215.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,1JT1D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
ZZS2_k127_277565_11	314345.SPV1_05457	0.0003385	50.0	2DSK7@1|root,33GGN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_277565_3	1042326.AZNV01000031_gene3669	2.533e-232	729.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,2UQIK@28211|Alphaproteobacteria,4BIGR@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
ZZS2_k127_277565_0	1396141.BATP01000003_gene5222	0.0	1514.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
ZZS2_k127_277565_5	595460.RRSWK_00692	8.657e-123	402.0	COG0039@1|root,COG0039@2|Bacteria,2IYB4@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the LDH MDH superfamily	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
ZZS2_k127_277565_4	338966.Ppro_1852	7.325e-190	603.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43T0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
ZZS2_k127_277565_9	452637.Oter_0554	1.148e-10	67.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
ZZS2_k127_277565_6	530564.Psta_2284	1.43e-100	334.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS2_k127_277565_1	1038860.AXAP01000015_gene2094	0.0	1417.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3JRH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	aldehyde-lyase activity	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
ZZS2_k127_277565_7	1267533.KB906737_gene1998	1.679e-46	175.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_277565_8	1403819.BATR01000112_gene3822	1.149e-14	73.0	COG0282@1|root,COG4869@1|root,COG0282@2|Bacteria,COG4869@2|Bacteria,46SKB@74201|Verrucomicrobia,2ITSN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acetokinase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetate_kinase,PTAC,cNMP_binding
ZZS2_k127_277670_3	32057.KB217478_gene704	1.161e-30	121.0	COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_277670_0	1173027.Mic7113_4161	1.631e-166	582.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_277670_2	395961.Cyan7425_0748	2.037e-53	190.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_277670_1	794903.OPIT5_07185	2.555e-130	437.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46V2T@74201|Verrucomicrobia,3K9RQ@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
ZZS2_k127_277670_4	1380394.JADL01000003_gene4839	1.834e-27	116.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
ZZS2_k127_277670_7	1122611.KB903957_gene36	1.386e-05	53.0	COG1366@1|root,COG1366@2|Bacteria,2I0EP@201174|Actinobacteria,4EQH2@85012|Streptosporangiales	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
ZZS2_k127_277670_5	382464.ABSI01000013_gene1769	2.845e-25	110.0	COG1959@1|root,COG1959@2|Bacteria,46X6R@74201|Verrucomicrobia,2IURA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ZZS2_k127_277670_6	644282.Deba_2016	6.062e-06	57.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WKB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_2781863_2	1396141.BATP01000039_gene1360	4.759e-51	185.0	COG0841@1|root,COG0841@2|Bacteria,46U0U@74201|Verrucomicrobia,2ITVP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_2781863_0	794903.OPIT5_25955	6.991e-117	388.0	COG0845@1|root,COG0845@2|Bacteria,46UG5@74201|Verrucomicrobia,3K865@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18901	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	HlyD_D23
ZZS2_k127_2781863_1	1403819.BATR01000054_gene1674	2.606e-55	200.0	COG1309@1|root,COG1309@2|Bacteria,46U8N@74201|Verrucomicrobia,2IUYV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
ZZS2_k127_2806368_1	929556.Solca_2621	4.533e-20	108.0	COG1520@1|root,COG1520@2|Bacteria,4PI1E@976|Bacteroidetes,1IYUU@117747|Sphingobacteriia	976|Bacteroidetes	Q	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2806368_0	583355.Caka_1736	2.238e-272	907.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_2806368_2	1042375.AFPL01000019_gene270	4.952e-10	65.0	2ETI8@1|root,33M24@2|Bacteria,1P8WS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2831774_4	1267535.KB906767_gene925	4.344e-15	86.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria,2JIVN@204432|Acidobacteriia	204432|Acidobacteriia	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
ZZS2_k127_2831774_2	1396141.BATP01000056_gene3279	2.984e-109	367.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Acetyltransf_6,FemAB_like
ZZS2_k127_2831774_0	497964.CfE428DRAFT_3293	3.597e-192	619.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C,EF-hand_5,Redoxin
ZZS2_k127_2831774_1	240016.ABIZ01000001_gene1581	1.259e-141	460.0	COG1082@1|root,COG1082@2|Bacteria,46UXT@74201|Verrucomicrobia,2ITIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2831774_3	382464.ABSI01000021_gene384	6.851e-45	175.0	COG0382@1|root,COG0382@2|Bacteria,46WYP@74201|Verrucomicrobia,2IURC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
ZZS2_k127_2897416_5	756272.Plabr_3500	2.838e-10	66.0	COG1763@1|root,COG1763@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03753,ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	-
ZZS2_k127_2897416_4	234267.Acid_4392	1.172e-71	254.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS2_k127_2897416_3	504472.Slin_2563	1.256e-77	269.0	COG0279@1|root,COG0279@2|Bacteria,4NKHI@976|Bacteroidetes,47N1Y@768503|Cytophagia	976|Bacteroidetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
ZZS2_k127_2897416_2	1123508.JH636442_gene3934	5.855e-160	518.0	COG4102@1|root,COG4102@2|Bacteria,2IX3Z@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_2897416_1	1210884.HG799478_gene15491	8.978e-170	558.0	COG2010@1|root,COG2010@2|Bacteria,2IWY5@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_2897416_0	497964.CfE428DRAFT_5245	1.444e-229	717.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_2901757_2	1449063.JMLS01000007_gene3566	1.992e-60	227.0	COG0666@1|root,COG0666@2|Bacteria,1V657@1239|Firmicutes,4HIDE@91061|Bacilli	91061|Bacilli	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
ZZS2_k127_2901757_0	575540.Isop_3370	3.363e-195	626.0	COG3386@1|root,COG3386@2|Bacteria,2J2MK@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
ZZS2_k127_2901757_5	1128427.KB904821_gene1634	6.609e-21	110.0	COG1404@1|root,COG3121@1|root,COG3291@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3121@2|Bacteria,COG3291@2|Bacteria,COG5549@2|Bacteria,1G2HU@1117|Cyanobacteria,1H9MN@1150|Oscillatoriales	2|Bacteria	O	PFAM Uncharacterised BCR, COG1649	prtB	-	1.1.3.9,3.2.1.4	ko:K01179,ko:K04618,ko:K07346,ko:K12685,ko:K17734	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R01098,R06200,R11307,R11308	RC00194	ko00000,ko00001,ko01000,ko01002,ko02000,ko02035,ko02044,ko03110	1.B.12.5.1,1.B.12.5.3	GH5,GH9	-	Autotransporter,F5_F8_type_C,Peptidase_M57,Peptidase_S8
ZZS2_k127_2901757_6	1341155.FSS13T_23940	2.197e-13	85.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
ZZS2_k127_2901757_3	1496688.ER33_07850	1.26e-54	222.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
ZZS2_k127_2901757_4	583355.Caka_1594	3.008e-37	163.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
ZZS2_k127_2901757_1	886293.Sinac_6489	2.19e-153	523.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_2904147_2	497964.CfE428DRAFT_6148	2.132e-25	112.0	2DTD6@1|root,33JTS@2|Bacteria,46WA4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
ZZS2_k127_2904147_3	1396418.BATQ01000166_gene1838	7.121e-22	98.0	2FCWX@1|root,344ZT@2|Bacteria,46WDE@74201|Verrucomicrobia,2IUVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
ZZS2_k127_2904147_0	1515746.HR45_13660	2.196e-83	286.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,1S2KN@1236|Gammaproteobacteria,2QDSG@267890|Shewanellaceae	1236|Gammaproteobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
ZZS2_k127_2904147_4	1196323.ALKF01000182_gene5243	7.142e-11	71.0	2CKD9@1|root,333BQ@2|Bacteria,1VIGZ@1239|Firmicutes,4HQNF@91061|Bacilli,26RC6@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2904147_1	56780.SYN_01127	4.332e-47	178.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2934200_3	1123070.KB899254_gene1196	0.0001023	50.0	COG5126@1|root,COG5126@2|Bacteria,46X0V@74201|Verrucomicrobia,2IWI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
ZZS2_k127_2934200_1	497964.CfE428DRAFT_3455	1.095e-53	205.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
ZZS2_k127_2934200_2	1403819.BATR01000168_gene5803	1.57e-39	159.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia,2IUNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_9,Lip_A_acyltrans
ZZS2_k127_2934200_0	278957.ABEA03000021_gene1724	2.982e-115	383.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,3K7KP@414999|Opitutae	414999|Opitutae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
ZZS2_k127_296220_4	452637.Oter_3178	9.582e-189	601.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia,3K801@414999|Opitutae	414999|Opitutae	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
ZZS2_k127_296220_22	565033.GACE_0504	6.579e-42	164.0	COG0500@1|root,arCOG04347@2157|Archaea,2Y7Z9@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ZZS2_k127_296220_1	1396418.BATQ01000168_gene1810	0.0	1186.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS2_k127_296220_7	497964.CfE428DRAFT_3440	5.18e-141	456.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Protein-arginine kinase	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
ZZS2_k127_296220_20	497964.CfE428DRAFT_3441	3.18e-52	189.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
ZZS2_k127_296220_18	861299.J421_5597	1.646e-57	219.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_296220_28	1396418.BATQ01000156_gene5584	5.404e-18	94.0	2EGCD@1|root,33A46@2|Bacteria,46Z2P@74201|Verrucomicrobia,2IWC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,DUF4339
ZZS2_k127_296220_5	1123508.JH636439_gene1278	1.815e-184	593.0	COG3119@1|root,COG3119@2|Bacteria,2IXIU@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
ZZS2_k127_296220_2	240016.ABIZ01000001_gene1549	5.426e-269	841.0	COG0330@1|root,COG0330@2|Bacteria,46TVK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_296220_10	349741.Amuc_1598	3.264e-93	333.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
ZZS2_k127_296220_0	903818.KI912269_gene112	0.0	1519.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,3Y2ZW@57723|Acidobacteria	57723|Acidobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
ZZS2_k127_296220_16	1123508.JH636440_gene2887	4.978e-69	243.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS2_k127_296220_8	497964.CfE428DRAFT_1528	3.239e-131	430.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia	74201|Verrucomicrobia	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
ZZS2_k127_296220_21	452637.Oter_0400	4.863e-52	193.0	COG1360@1|root,COG1360@2|Bacteria,46VC4@74201|Verrucomicrobia,3K7YD@414999|Opitutae	414999|Opitutae	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
ZZS2_k127_296220_13	521674.Plim_2583	2.27e-79	273.0	COG1291@1|root,COG1291@2|Bacteria	2|Bacteria	N	archaeal or bacterial-type flagellum-dependent cell motility	motA	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
ZZS2_k127_296220_19	278957.ABEA03000202_gene4307	1.472e-55	209.0	COG1191@1|root,COG1191@2|Bacteria,46TPW@74201|Verrucomicrobia,3K7F7@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_296220_26	452637.Oter_0404	1.995e-26	122.0	COG1419@1|root,COG1419@2|Bacteria,46VBY@74201|Verrucomicrobia,3K9JP@414999|Opitutae	414999|Opitutae	N	protein localization to endoplasmic reticulum	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	-
ZZS2_k127_296220_3	452637.Oter_0405	4.995e-235	747.0	COG1298@1|root,COG1298@2|Bacteria,46TTN@74201|Verrucomicrobia,3K7G5@414999|Opitutae	414999|Opitutae	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
ZZS2_k127_296220_17	452637.Oter_0406	7.159e-65	234.0	COG1377@1|root,COG1377@2|Bacteria,46U7X@74201|Verrucomicrobia,3K76M@414999|Opitutae	414999|Opitutae	NU	FlhB HrpN YscU SpaS Family	-	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
ZZS2_k127_296220_24	398767.Glov_3288	4.715e-29	126.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WQ35@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
ZZS2_k127_296220_29	1031288.AXAA01000001_gene2359	4.867e-17	83.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia,36KJW@31979|Clostridiaceae	186801|Clostridia	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
ZZS2_k127_296220_14	452637.Oter_0409	7.321e-77	272.0	COG1338@1|root,COG1338@2|Bacteria,46USW@74201|Verrucomicrobia,3K7PQ@414999|Opitutae	414999|Opitutae	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
ZZS2_k127_296220_34	218497.CAB373	3.818e-05	53.0	COG3190@1|root,COG3190@2|Bacteria	2|Bacteria	N	flagellar	fliZ	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
ZZS2_k127_296220_27	1345023.M467_04345	5.809e-22	101.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli	91061|Bacilli	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliY	GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
ZZS2_k127_296220_11	452637.Oter_0412	2.893e-91	314.0	COG1868@1|root,COG1868@2|Bacteria,46TJ7@74201|Verrucomicrobia,3K7H2@414999|Opitutae	414999|Opitutae	N	Flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
ZZS2_k127_296220_25	452637.Oter_0413	1.866e-28	122.0	COG1580@1|root,COG1580@2|Bacteria,46W5Y@74201|Verrucomicrobia,3K86H@414999|Opitutae	414999|Opitutae	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
ZZS2_k127_296220_32	1128398.Curi_c15950	7.641e-13	74.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia,2697H@186813|unclassified Clostridiales	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
ZZS2_k127_296220_30	382464.ABSI01000016_gene700	1.604e-16	89.0	COG3334@1|root,COG3334@2|Bacteria,46WC3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM MgtE intracellular	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_296220_6	278957.ABEA03000189_gene987	7.404e-160	516.0	COG1157@1|root,COG1157@2|Bacteria,46UKN@74201|Verrucomicrobia,3K7FP@414999|Opitutae	414999|Opitutae	N	ATP synthase alpha/beta family, beta-barrel domain	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS2_k127_296220_33	1071073.KI530537_gene2272	2.049e-07	61.0	COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HGNK@91061|Bacilli,1ZQRU@1386|Bacillus	91061|Bacilli	NU	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
ZZS2_k127_296220_12	452637.Oter_0423	7.526e-90	307.0	COG1536@1|root,COG1536@2|Bacteria,46US0@74201|Verrucomicrobia,3K7R6@414999|Opitutae	414999|Opitutae	N	FliG middle domain	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
ZZS2_k127_296220_9	452637.Oter_0424	5.134e-117	395.0	COG1766@1|root,COG1766@2|Bacteria,46UUW@74201|Verrucomicrobia,3K76G@414999|Opitutae	414999|Opitutae	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
ZZS2_k127_296220_31	452637.Oter_0425	1.861e-14	78.0	COG1677@1|root,COG1677@2|Bacteria,46WQE@74201|Verrucomicrobia,3K8GA@414999|Opitutae	414999|Opitutae	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
ZZS2_k127_296220_23	278957.ABEA03000189_gene992	5.044e-36	144.0	COG1558@1|root,COG1558@2|Bacteria,46VMA@74201|Verrucomicrobia,3K86M@414999|Opitutae	414999|Opitutae	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
ZZS2_k127_296220_15	926550.CLDAP_28810	2.011e-73	256.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
ZZS2_k127_2971479_10	1123008.KB905700_gene2139	1.516e-46	170.0	COG1680@1|root,COG1680@2|Bacteria,4PHZD@976|Bacteroidetes,2G1GG@200643|Bacteroidia,2312Z@171551|Porphyromonadaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_2971479_1	246197.MXAN_3415	1.84e-289	912.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
ZZS2_k127_2971479_3	452637.Oter_3626	2.139e-127	417.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,46SM2@74201|Verrucomicrobia,3K9SZ@414999|Opitutae	414999|Opitutae	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2971479_16	398767.Glov_1268	1.455e-14	82.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_2971479_17	530564.Psta_3933	5.4e-11	73.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,Laminin_G_3
ZZS2_k127_2971479_5	1267535.KB906767_gene661	4.338e-115	386.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
ZZS2_k127_2971479_4	497964.CfE428DRAFT_0481	8.556e-125	432.0	COG1858@1|root,COG3391@1|root,COG4733@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,COG5276@2|Bacteria,46U43@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,Laminin_G_3,PKD
ZZS2_k127_2971479_15	1396141.BATP01000034_gene4198	8.257e-15	89.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_2971479_12	1356852.N008_13480	1.267e-26	128.0	COG2706@1|root,COG3468@1|root,COG2706@2|Bacteria,COG3468@2|Bacteria,4PPV8@976|Bacteroidetes,47V28@768503|Cytophagia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_2971479_18	1276920.ADIAG_01370	2.882e-10	74.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Malectin,PKD
ZZS2_k127_2971479_8	1499967.BAYZ01000171_gene5616	5.404e-62	231.0	COG4420@1|root,COG4420@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1003)	yejC	-	-	-	-	-	-	-	-	-	-	-	DUF1003
ZZS2_k127_2971479_0	247490.KSU1_C1668	6.052e-311	992.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
ZZS2_k127_2971479_6	595460.RRSWK_02559	3.033e-104	358.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
ZZS2_k127_2971479_7	452637.Oter_1554	1.196e-79	283.0	COG1538@1|root,COG1538@2|Bacteria,46WHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_2971479_13	335284.Pcryo_1777	5.766e-25	105.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,3NIYQ@468|Moraxellaceae	1236|Gammaproteobacteria	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
ZZS2_k127_2971479_11	278957.ABEA03000006_gene4219	1.56e-44	170.0	COG1595@1|root,COG1595@2|Bacteria,46WAA@74201|Verrucomicrobia,3K8C3@414999|Opitutae	414999|Opitutae	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_2971479_14	1396141.BATP01000024_gene845	1.985e-15	82.0	2DGAX@1|root,2ZV7P@2|Bacteria,46WTW@74201|Verrucomicrobia,2IW8D@203494|Verrucomicrobiae	74201|Verrucomicrobia	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
ZZS2_k127_2971479_2	1278073.MYSTI_01766	1.445e-134	450.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_2971479_9	246197.MXAN_3650	7.929e-47	175.0	COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_2975386_1	886293.Sinac_2439	1.257e-293	927.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IX7F@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
ZZS2_k127_2975386_2	251229.Chro_2349	1.377e-211	685.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria,1GQNZ@1117|Cyanobacteria	1117|Cyanobacteria	G	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_2975386_24	338963.Pcar_2836	1.192e-30	127.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,42MZG@68525|delta/epsilon subdivisions,2WKZ3@28221|Deltaproteobacteria,43UBA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
ZZS2_k127_2975386_14	497964.CfE428DRAFT_5213	1.679e-70	243.0	COG4650@1|root,COG4650@2|Bacteria,46TFD@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	Regulator of RNA terminal phosphate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	RtcR,Sigma54_activat
ZZS2_k127_2975386_9	1123508.JH636440_gene2191	1.369e-132	436.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
ZZS2_k127_2975386_11	401053.AciPR4_0814	1.799e-121	396.0	KOG1573@1|root,2Z822@2|Bacteria,3Y3AN@57723|Acidobacteria,2JKNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Myo-inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
ZZS2_k127_2975386_5	794903.OPIT5_30870	3.576e-160	510.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	414999|Opitutae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
ZZS2_k127_2975386_15	478741.JAFS01000002_gene866	1.217e-67	234.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,37GJ7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
ZZS2_k127_2975386_7	1170562.Cal6303_2841	8.501e-156	511.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0YK@1117|Cyanobacteria,1HJQH@1161|Nostocales	1117|Cyanobacteria	Q	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CHRD,DUF4114,DUF4214,Exo_endo_phos,Phytase-like,W_rich_C
ZZS2_k127_2975386_6	1210884.HG799463_gene10258	9.335e-157	506.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,2J25N@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase,Acetyltransf_1
ZZS2_k127_2975386_31	118173.KB235914_gene2439	2.066e-13	81.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind,P_proprotein,Peptidase_S8
ZZS2_k127_2975386_16	452637.Oter_0080	5.343e-52	201.0	COG0810@1|root,COG1595@1|root,COG0810@2|Bacteria,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,3K9H7@414999|Opitutae	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_2975386_18	497964.CfE428DRAFT_1741	1.894e-44	166.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
ZZS2_k127_2975386_22	240016.ABIZ01000001_gene908	2.904e-42	173.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
ZZS2_k127_2975386_28	1396418.BATQ01000003_gene1352	9.851e-19	94.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,2IURI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
ZZS2_k127_2975386_34	1385935.N836_23380	3.906e-07	55.0	COG5548@1|root,COG5548@2|Bacteria,1G9NN@1117|Cyanobacteria,1HHD5@1150|Oscillatoriales	1117|Cyanobacteria	S	Transmembrane proteins 14C	-	-	-	-	-	-	-	-	-	-	-	-	Tmemb_14
ZZS2_k127_2975386_33	517417.Cpar_0783	1.015e-09	62.0	2DIK4@1|root,303HI@2|Bacteria,1FFNU@1090|Chlorobi	1090|Chlorobi	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
ZZS2_k127_2975386_4	497964.CfE428DRAFT_5300	5.166e-173	558.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_2975386_21	497964.CfE428DRAFT_1749	6.339e-44	164.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
ZZS2_k127_2975386_35	395495.Lcho_1044	0.0001	52.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,1KKTV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
ZZS2_k127_2975386_17	497964.CfE428DRAFT_4947	6.195e-46	169.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
ZZS2_k127_2975386_30	1396141.BATP01000026_gene1042	5.444e-14	78.0	2F8IJ@1|root,340XC@2|Bacteria,46WTZ@74201|Verrucomicrobia,2IUYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2975386_19	497964.CfE428DRAFT_4946	3.696e-44	167.0	2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2975386_10	1210884.HG799464_gene11020	6.296e-125	414.0	COG1541@1|root,COG1541@2|Bacteria,2IXI4@203682|Planctomycetes	203682|Planctomycetes	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
ZZS2_k127_2975386_20	370438.PTH_0289	6.187e-44	168.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,261YY@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
ZZS2_k127_2975386_29	1254432.SCE1572_28085	3.621e-17	93.0	COG5036@1|root,COG5036@2|Bacteria	2|Bacteria	P	cellular response to phosphate starvation	-	-	-	-	-	-	-	-	-	-	-	-	VTC
ZZS2_k127_2975386_13	497964.CfE428DRAFT_2414	6.117e-88	305.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
ZZS2_k127_2975386_32	497964.CfE428DRAFT_1546	4.399e-13	77.0	28T9X@1|root,2ZFII@2|Bacteria,46WJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2975386_27	452637.Oter_0063	1.984e-19	91.0	COG2823@1|root,COG2823@2|Bacteria,46XV8@74201|Verrucomicrobia,3K8D0@414999|Opitutae	414999|Opitutae	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS2_k127_2975386_8	1173024.KI912149_gene6154	9.46e-149	490.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
ZZS2_k127_2975386_3	234267.Acid_1992	2.118e-186	606.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_2975386_0	344747.PM8797T_04490	3.488e-305	956.0	COG0613@1|root,COG0613@2|Bacteria,2IY27@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2975386_26	497964.CfE428DRAFT_1163	4.217e-27	130.0	COG3506@1|root,COG4254@1|root,COG3506@2|Bacteria,COG4254@2|Bacteria,46SQ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lyase_8,Lyase_N,Lyase_catalyt
ZZS2_k127_2975386_25	1121946.AUAX01000005_gene5510	6.705e-29	136.0	COG3401@1|root,COG5563@1|root,COG3401@2|Bacteria,COG5563@2|Bacteria,2GRWY@201174|Actinobacteria,4DMB3@85008|Micromonosporales	201174|Actinobacteria	S	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2975386_23	1280390.CBQR020000166_gene4413	1.379e-39	171.0	COG4733@1|root,COG4733@2|Bacteria,1TQB3@1239|Firmicutes,4HU7T@91061|Bacilli,26RV2@186822|Paenibacillaceae	91061|Bacilli	G	Cellulose 1,4-beta-cellobiosidase	bglC3	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Glyco_hydro_48,fn3
ZZS2_k127_2975386_12	1173024.KI912152_gene820	1.81e-108	358.0	COG4335@1|root,COG4335@2|Bacteria,1G9AB@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
ZZS2_k127_2999083_3	1396141.BATP01000026_gene1022	5.52e-75	263.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Laminin_G_3,PA14
ZZS2_k127_2999083_4	498848.TaqDRAFT_4878	2.533e-46	183.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2999083_1	452637.Oter_2206	3.455e-107	353.0	COG1136@1|root,COG1136@2|Bacteria,46SAX@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_2999083_0	240016.ABIZ01000001_gene5721	3.893e-248	789.0	COG0577@1|root,COG0577@2|Bacteria,46S5D@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2999083_2	1439940.BAY1663_01913	1.428e-89	314.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
ZZS2_k127_2999083_5	1396141.BATP01000034_gene4198	0.0001385	46.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_3017956_2	861299.J421_5609	8.708e-117	384.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
ZZS2_k127_3017956_0	886293.Sinac_2682	4.334e-166	536.0	COG1129@1|root,COG1129@2|Bacteria,2IXQH@203682|Planctomycetes	203682|Planctomycetes	G	transport system, ATPase	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
ZZS2_k127_3017956_6	861299.J421_5600	1.295e-78	276.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
ZZS2_k127_3017956_1	1123368.AUIS01000044_gene15	3.456e-152	495.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS2_k127_3017956_3	661478.OP10G_0723	1.023e-101	340.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_3017956_13	267608.RSp1526	2.088e-06	62.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS2_k127_3017956_10	945713.IALB_1460	2.056e-28	120.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K14061	-	-	-	-	ko00000	-	-	-	Usp
ZZS2_k127_3017956_8	497964.CfE428DRAFT_5882	4.6e-63	232.0	COG3213@1|root,COG3213@2|Bacteria,46VTH@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrS
ZZS2_k127_3017956_4	497964.CfE428DRAFT_3249	7.182e-99	331.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
ZZS2_k127_3017956_5	478741.JAFS01000001_gene1828	7.649e-95	325.0	COG0502@1|root,COG0502@2|Bacteria	2|Bacteria	H	biotin synthase activity	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
ZZS2_k127_3017956_14	1134413.ANNK01000111_gene1554	0.0002096	46.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3017956_7	765913.ThidrDRAFT_4457	3.397e-74	263.0	COG4924@1|root,COG4924@2|Bacteria,1QXCY@1224|Proteobacteria,1RZ8F@1236|Gammaproteobacteria,1WXQV@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
ZZS2_k127_3017956_11	179408.Osc7112_5431	3.004e-24	108.0	COG2442@1|root,COG2442@2|Bacteria,1G83Q@1117|Cyanobacteria,1HCXY@1150|Oscillatoriales	1117|Cyanobacteria	S	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3017956_9	56110.Oscil6304_2808	5.573e-38	146.0	2DPPF@1|root,332VS@2|Bacteria,1GEA9@1117|Cyanobacteria,1HFSF@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_302824_3	497964.CfE428DRAFT_3497	1.7e-174	561.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
ZZS2_k127_302824_9	1122915.AUGY01000087_gene5226	8.166e-57	215.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
ZZS2_k127_302824_2	497964.CfE428DRAFT_2523	0.0	1408.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
ZZS2_k127_302824_4	562970.Btus_1769	6.363e-111	379.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
ZZS2_k127_302824_0	448385.sce7733	0.0	1890.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
ZZS2_k127_302824_10	1123508.JH636440_gene2931	2.88e-51	184.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_302824_6	1340493.JNIF01000003_gene3872	1.785e-97	337.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343,SSF
ZZS2_k127_302824_12	498761.HM1_0145	3.384e-13	85.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
ZZS2_k127_302824_8	1121897.AUGO01000002_gene2177	1.329e-57	231.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_302824_7	269798.CHU_2399	2.095e-59	237.0	COG3291@1|root,COG3291@2|Bacteria,4NW5C@976|Bacteroidetes,47RYD@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
ZZS2_k127_302824_11	28444.JODQ01000018_gene7284	1.36e-34	155.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
ZZS2_k127_302824_1	748280.NH8B_2766	0.0	1632.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
ZZS2_k127_302824_5	1396418.BATQ01000004_gene1360	3.6e-104	350.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_3055343_20	1183438.GKIL_3176	2.851e-20	102.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asp_protease_2,PDZ,PDZ_2,Peptidase_M28,Peptidase_S55
ZZS2_k127_3055343_19	1396418.BATQ01000178_gene2833	6.128e-21	96.0	COG1607@1|root,COG1607@2|Bacteria,46X8N@74201|Verrucomicrobia,2IV0R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS2_k127_3055343_14	700598.Niako_0361	3.185e-51	190.0	COG1247@1|root,COG1247@2|Bacteria,4NPIE@976|Bacteroidetes,1IZMK@117747|Sphingobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
ZZS2_k127_3055343_5	1121406.JAEX01000012_gene636	1.905e-148	482.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_3055343_0	452637.Oter_2432	8.759e-260	810.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
ZZS2_k127_3055343_6	497964.CfE428DRAFT_4585	9.951e-114	370.0	COG0175@1|root,COG0175@2|Bacteria,46SNE@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
ZZS2_k127_3055343_4	452637.Oter_2430	8.361e-156	499.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,3K7NR@414999|Opitutae	74201|Verrucomicrobia	H	PFAM phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
ZZS2_k127_3055343_1	497964.CfE428DRAFT_4587	4.815e-233	726.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
ZZS2_k127_3055343_11	935948.KE386494_gene470	5.311e-65	229.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,24GDY@186801|Clostridia,42GWA@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
ZZS2_k127_3055343_24	903818.KI912269_gene142	8.16e-05	56.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Flg_new
ZZS2_k127_3055343_22	1396141.BATP01000018_gene1531	5.843e-16	93.0	COG2133@1|root,COG2755@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,46VBR@74201|Verrucomicrobia,2IUWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF1800,DUF5011,PA14
ZZS2_k127_3055343_23	794903.OPIT5_22660	7.515e-07	63.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3055343_3	240016.ABIZ01000001_gene1867	6.636e-179	584.0	COG0475@1|root,COG0475@2|Bacteria,46U4K@74201|Verrucomicrobia,2IV1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
ZZS2_k127_3055343_12	323848.Nmul_A1366	1.083e-57	209.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,2WB4B@28216|Betaproteobacteria,372A6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_3055343_2	1156937.MFUM_690067	6.116e-197	631.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,37G1H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
ZZS2_k127_3055343_13	1121468.AUBR01000026_gene2919	1.411e-51	191.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,42GDH@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
ZZS2_k127_3055343_7	760568.Desku_1244	4.321e-101	341.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,260PG@186807|Peptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
ZZS2_k127_3055343_8	313628.LNTAR_04061	3.794e-82	287.0	COG0552@1|root,COG0552@2|Bacteria	2|Bacteria	U	SRP-dependent cotranslational protein targeting to membrane	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
ZZS2_k127_3055343_10	1379698.RBG1_1C00001G1246	6.091e-66	236.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
ZZS2_k127_3055343_16	497964.CfE428DRAFT_4665	7.968e-32	130.0	COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
ZZS2_k127_3055343_18	497964.CfE428DRAFT_6672	4.273e-27	111.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS2_k127_3055343_15	497964.CfE428DRAFT_6673	3.389e-33	131.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS2_k127_3055343_21	1396141.BATP01000019_gene1732	2.935e-19	100.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_3055343_9	886293.Sinac_3618	1.887e-73	259.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_3083813_5	338969.Rfer_4149	1.979e-27	114.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,2W3U8@28216|Betaproteobacteria,4AI76@80864|Comamonadaceae	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3083813_8	338969.Rfer_0832	2.855e-10	64.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4ABI0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ZZS2_k127_3083813_9	485913.Krac_5424	0.0005061	44.0	COG1881@1|root,COG1881@2|Bacteria,2G6ZP@200795|Chloroflexi	200795|Chloroflexi	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
ZZS2_k127_3083813_0	497964.CfE428DRAFT_3898	5.321e-123	411.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_3083813_2	1190603.AJYD01000028_gene3781	1.544e-84	287.0	2F983@1|root,341JD@2|Bacteria,1N5IA@1224|Proteobacteria,1SQ9Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3083813_1	469381.Dpep_1245	6.641e-108	358.0	COG0428@1|root,COG0428@2|Bacteria,3T9UW@508458|Synergistetes	508458|Synergistetes	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
ZZS2_k127_3083813_3	1184267.A11Q_2451	1.75e-53	218.0	2EBH8@1|root,335HR@2|Bacteria	2|Bacteria	S	Pfam:DUF946	-	-	-	-	-	-	-	-	-	-	-	-	Vps62
ZZS2_k127_3083813_4	111781.Lepto7376_0894	1.631e-39	172.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1GBAY@1117|Cyanobacteria	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_3083813_7	65393.PCC7424_1997	1.881e-22	116.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G4IS@1117|Cyanobacteria,3KKQ9@43988|Cyanothece	1117|Cyanobacteria	QU	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
ZZS2_k127_3112439_9	1396141.BATP01000059_gene2520	4.485e-15	87.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
ZZS2_k127_3112439_7	1396141.BATP01000028_gene2285	3.457e-38	157.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
ZZS2_k127_3112439_1	861299.J421_1753	7.016e-273	885.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_3112439_4	234267.Acid_6138	3.068e-125	424.0	COG0457@1|root,COG2010@1|root,COG0457@2|Bacteria,COG2010@2|Bacteria,3Y67F@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
ZZS2_k127_3112439_8	1144932.ATTF01000017_gene1171	3.697e-24	113.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
ZZS2_k127_3112439_13	316067.Geob_1779	5.875e-06	58.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria,43TJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_3112439_5	1382306.JNIM01000001_gene3956	2.309e-93	322.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
ZZS2_k127_3112439_10	309807.SRU_0977	6.243e-08	66.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3112439_0	671143.DAMO_0980	3.013e-284	887.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
ZZS2_k127_3112439_2	671143.DAMO_0981	7.592e-237	744.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
ZZS2_k127_3112439_6	335543.Sfum_0642	1.242e-41	171.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2MR6C@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
ZZS2_k127_3112439_3	1121405.dsmv_2914	1.906e-128	426.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI07@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_3112439_14	333138.LQ50_13850	7.28e-06	58.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,1ZD6V@1386|Bacillus	91061|Bacilli	M	Glycosyl Transferase	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_3112439_11	627192.SLG_07050	3.48e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
ZZS2_k127_3112439_12	1210884.HG799471_gene14563	3.48e-07	63.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_3141676_0	485913.Krac_4586	6.845e-99	361.0	COG2133@1|root,COG2355@1|root,COG2133@2|Bacteria,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_3141676_1	1380347.JNII01000005_gene2882	1.323e-23	119.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,2GPF1@201174|Actinobacteria	201174|Actinobacteria	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
ZZS2_k127_3154360_13	497964.CfE428DRAFT_1861	1.653e-44	169.0	COG1595@1|root,COG4194@1|root,COG1595@2|Bacteria,COG4194@2|Bacteria,46TQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_3154360_4	497964.CfE428DRAFT_5010	1.559e-160	519.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3154360_9	1128427.KB904821_gene1968	6.106e-87	298.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS2_k127_3154360_1	497964.CfE428DRAFT_6007	8.277e-200	646.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46UV7@74201|Verrucomicrobia	2|Bacteria	CG	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH,HEAT_2
ZZS2_k127_3154360_16	1303518.CCALI_01379	1.606e-10	73.0	COG1413@1|root,COG2211@1|root,COG1413@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	3.4.11.2	ko:K01256,ko:K16210	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02000	2.A.2.5	-	-	HEAT_2,MFS_1
ZZS2_k127_3154360_3	452637.Oter_0123	1.632e-184	599.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
ZZS2_k127_3154360_2	452637.Oter_4259	2.308e-187	591.0	COG0524@1|root,COG0524@2|Bacteria,46TGU@74201|Verrucomicrobia,3K7M0@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
ZZS2_k127_3154360_14	886293.Sinac_5104	8.132e-36	145.0	COG3468@1|root,COG3468@2|Bacteria,2J1BR@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3154360_7	452637.Oter_1502	2.246e-103	346.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_3154360_8	452637.Oter_1501	6.392e-95	335.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
ZZS2_k127_3154360_5	382464.ABSI01000010_gene3676	8.423e-151	492.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
ZZS2_k127_3154360_11	497964.CfE428DRAFT_5735	1.234e-49	197.0	COG4796@1|root,COG4796@2|Bacteria,46STU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
ZZS2_k127_3154360_15	203124.Tery_1605	2.924e-13	81.0	COG4972@1|root,COG4972@2|Bacteria,1G0A3@1117|Cyanobacteria,1H7GE@1150|Oscillatoriales	1117|Cyanobacteria	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS2_k127_3154360_6	555079.Toce_0859	1.082e-103	352.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
ZZS2_k127_3154360_12	1382359.JIAL01000001_gene2207	1.05e-46	173.0	COG2905@1|root,COG2905@2|Bacteria,3Y5NG@57723|Acidobacteria,2JN0N@204432|Acidobacteriia	204432|Acidobacteriia	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS2_k127_3154360_17	1403819.BATR01000181_gene6112	3.608e-07	63.0	2BY38@1|root,33M03@2|Bacteria	1403819.BATR01000181_gene6112|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3154360_0	497964.CfE428DRAFT_0797	1.741e-281	893.0	COG0060@1|root,COG0060@2|Bacteria,46SEC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
ZZS2_k127_3154360_10	1396418.BATQ01000046_gene6147	6.639e-73	253.0	COG1082@1|root,COG1082@2|Bacteria,46WKR@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_315797_4	1267535.KB906767_gene2986	1.115e-50	189.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_315797_2	251221.35211765	1.644e-197	642.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_315797_0	452637.Oter_1898	1.834e-231	740.0	COG0577@1|root,COG0577@2|Bacteria	452637.Oter_1898|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_315797_1	452637.Oter_1855	1.414e-202	656.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_315797_3	1267535.KB906767_gene2985	3.557e-86	296.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_3159382_7	278957.ABEA03000061_gene3161	1.207e-64	222.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS2_k127_3159382_3	240016.ABIZ01000001_gene2202	1.556e-113	376.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS2_k127_3159382_4	497964.CfE428DRAFT_4766	6.268e-84	289.0	COG1039@1|root,COG1039@2|Bacteria,46UTB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
ZZS2_k127_3159382_5	314230.DSM3645_11537	4.005e-77	272.0	COG1194@1|root,COG1194@2|Bacteria,2IY33@203682|Planctomycetes	203682|Planctomycetes	L	COG1194 A G-specific DNA glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
ZZS2_k127_3159382_1	1173026.Glo7428_4012	4.214e-158	516.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
ZZS2_k127_3159382_6	1396418.BATQ01000113_gene4671	1.94e-72	247.0	COG0450@1|root,COG0450@2|Bacteria,46STI@74201|Verrucomicrobia,2IUMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_3159382_9	314264.ROS217_14991	1.405e-06	55.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3159382_2	485916.Dtox_1120	1.295e-131	430.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,260AS@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
ZZS2_k127_3159382_8	1303518.CCALI_00360	4.975e-64	235.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
ZZS2_k127_3159382_0	1340493.JNIF01000003_gene2245	1.148e-163	527.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
ZZS2_k127_316518_1	1124780.ANNU01000071_gene1021	4.699e-145	471.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
ZZS2_k127_316518_2	278957.ABEA03000080_gene3200	1.375e-119	399.0	COG1301@1|root,COG1301@2|Bacteria,46U9C@74201|Verrucomicrobia,3K7YK@414999|Opitutae	414999|Opitutae	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
ZZS2_k127_316518_4	1123242.JH636435_gene2487	4.595e-96	351.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_316518_5	497964.CfE428DRAFT_2982	3.239e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_316518_0	583355.Caka_2778	9.986e-242	811.0	COG3334@1|root,COG3334@2|Bacteria	2|Bacteria	S	PFAM MgtE intracellular	ylxF	-	-	ko:K02383	-	-	-	-	ko00000,ko02035	-	-	-	MgtE_N
ZZS2_k127_31681_1	1166018.FAES_5169	5.213e-69	254.0	COG3291@1|root,COG3291@2|Bacteria,4NMA6@976|Bacteroidetes	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
ZZS2_k127_31681_0	1313421.JHBV01000041_gene3629	7.789e-190	619.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
ZZS2_k127_3174387_1	497964.CfE428DRAFT_1603	4.845e-132	427.0	COG0673@1|root,COG0673@2|Bacteria,46TYR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_3174387_0	1267533.KB906740_gene120	4.314e-136	445.0	COG0666@1|root,COG0666@2|Bacteria,3Y6UE@57723|Acidobacteria,2JK4Y@204432|Acidobacteriia	204432|Acidobacteriia	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2
ZZS2_k127_3220490_0	1116369.KB890025_gene5283	8.659e-108	362.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS2_k127_3220490_1	1125973.JNLC01000011_gene481	1.453e-52	194.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
ZZS2_k127_3248575_1	1123242.JH636434_gene4621	3.089e-73	251.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_3248575_0	1123242.JH636434_gene5289	9.799e-204	642.0	COG0673@1|root,COG0673@2|Bacteria,2IX34@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_3248823_3	395493.BegalDRAFT_2161	8.857e-101	356.0	COG1305@1|root,COG1305@2|Bacteria,1QQE9@1224|Proteobacteria,1SK9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ZZS2_k127_3248823_2	56107.Cylst_0588	5.441e-102	356.0	COG1721@1|root,COG1721@2|Bacteria,1G1ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_3248823_0	317619.ANKN01000038_gene66	3.828e-128	417.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1MNN3@1212|Prochloraceae	1117|Cyanobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_3248823_1	1499967.BAYZ01000177_gene5743	7.493e-113	381.0	COG2204@1|root,COG2204@2|Bacteria,2NQHI@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_3279372_1	1121447.JONL01000009_gene2551	7.109e-149	493.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2M8H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
ZZS2_k127_3279372_0	340177.Cag_1407	1.704e-195	633.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_3279372_2	340177.Cag_1408	1.807e-117	400.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
ZZS2_k127_3279372_9	1000565.METUNv1_01465	7.683e-09	67.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VHW3@28216|Betaproteobacteria,2KV52@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18901	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_3279372_8	1121918.ARWE01000001_gene3665	2.54e-15	90.0	COG1538@1|root,COG3170@1|root,COG1538@2|Bacteria,COG3170@2|Bacteria,1NEHN@1224|Proteobacteria,43BDI@68525|delta/epsilon subdivisions,2X6S7@28221|Deltaproteobacteria,43W3Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_3279372_7	272123.Anacy_4632	4.638e-27	131.0	COG0652@1|root,COG2931@1|root,COG0652@2|Bacteria,COG2931@2|Bacteria,1G3Y9@1117|Cyanobacteria	1117|Cyanobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Cadherin,HemolysinCabind,Pro_isomerase
ZZS2_k127_3279372_5	1218084.BBJK01000039_gene3627	1.323e-60	211.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,1K3AS@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
ZZS2_k127_3279372_4	1396141.BATP01000007_gene5571	1.769e-61	237.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
ZZS2_k127_3279372_6	160860.XP_007350285.1	1.277e-41	175.0	2CXQ1@1|root,2RYZR@2759|Eukaryota,39T0P@33154|Opisthokonta,3NWV2@4751|Fungi	4751|Fungi	G	Endonuclease Exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_3279372_3	1396141.BATP01000027_gene1109	6.858e-88	304.0	COG4775@1|root,COG4775@2|Bacteria,46UZC@74201|Verrucomicrobia,2IV9A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
ZZS2_k127_3279372_10	1278073.MYSTI_00123	0.0008199	48.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_3284187_2	1123508.JH636442_gene4054	7.091e-226	724.0	COG2010@1|root,COG2010@2|Bacteria,2IXIG@203682|Planctomycetes	2|Bacteria	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_3284187_0	240016.ABIZ01000001_gene765	3.792e-259	813.0	COG3119@1|root,COG3119@2|Bacteria,46TQV@74201|Verrucomicrobia,2IWK5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS2_k127_3284187_3	1123242.JH636435_gene2614	1.475e-195	625.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
ZZS2_k127_3284187_1	1519464.HY22_04590	2.599e-244	774.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
ZZS2_k127_3284187_4	497964.CfE428DRAFT_6294	9.947e-27	126.0	2E0WZ@1|root,32WDX@2|Bacteria,46WD0@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3297611_3	269797.Mbar_A1626	6.372e-33	143.0	COG1404@1|root,arCOG02512@1|root,arCOG00702@2157|Archaea,arCOG02512@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Calx-beta,Inhibitor_I9,Peptidase_S8
ZZS2_k127_3297611_1	765913.ThidrDRAFT_4512	4.788e-153	514.0	COG1672@1|root,COG1672@2|Bacteria,1NTWM@1224|Proteobacteria	1224|Proteobacteria	O	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,TIR_2,Trypsin_2
ZZS2_k127_3297611_2	497964.CfE428DRAFT_0066	1.294e-75	283.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_3297611_0	886293.Sinac_0920	1.785e-155	502.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_3297611_4	1454007.JAUG01000160_gene988	2.988e-30	139.0	COG4166@1|root,COG5295@1|root,COG4166@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1IPUC@117747|Sphingobacteriia	976|Bacteroidetes	EUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
ZZS2_k127_3300337_11	886293.Sinac_0796	1.594e-28	115.0	COG0614@1|root,COG0614@2|Bacteria,2J075@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
ZZS2_k127_3300337_3	485913.Krac_6839	5.025e-78	275.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
ZZS2_k127_3300337_7	656519.Halsa_1446	4.249e-64	235.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WAFC@53433|Halanaerobiales	186801|Clostridia	U	PFAM Bacterial type II secretion system protein F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_3300337_16	472759.Nhal_0442	2.252e-05	55.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1WY85@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein H	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
ZZS2_k127_3300337_17	269799.Gmet_3370	0.0002573	53.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
ZZS2_k127_3300337_14	7165.AGAP008439-PA	1.669e-07	63.0	29K9Z@1|root,2RTIX@2759|Eukaryota,38ZAF@33154|Opisthokonta,3C5ZN@33208|Metazoa,3DM1C@33213|Bilateria,423GH@6656|Arthropoda,3SS6T@50557|Insecta,455TU@7147|Diptera,45DRB@7148|Nematocera	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3300337_12	933262.AXAM01000042_gene1817	1.326e-18	98.0	COG1555@1|root,COG3156@1|root,COG1555@2|Bacteria,COG3156@2|Bacteria,1PQMW@1224|Proteobacteria,42T9B@68525|delta/epsilon subdivisions,2WPYT@28221|Deltaproteobacteria,2MKAN@213118|Desulfobacterales	28221|Deltaproteobacteria	LU	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
ZZS2_k127_3300337_9	497964.CfE428DRAFT_2202	1.646e-35	155.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_3300337_5	1123261.AXDW01000002_gene1591	2.223e-67	238.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1X39V@135614|Xanthomonadales	135614|Xanthomonadales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
ZZS2_k127_3300337_8	497964.CfE428DRAFT_6361	3.35e-39	150.0	2FICZ@1|root,34A57@2|Bacteria,46W7Z@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3300337_2	497964.CfE428DRAFT_6362	5.235e-115	379.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3300337_1	240016.ABIZ01000001_gene1151	1.209e-188	597.0	COG0535@1|root,COG0535@2|Bacteria,46TZN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
ZZS2_k127_3300337_13	452637.Oter_3452	5.438e-12	77.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23,Methyltransf_25
ZZS2_k127_3300337_4	356851.JOAN01000003_gene1397	1.445e-68	242.0	COG4122@1|root,COG4122@2|Bacteria,2IEVU@201174|Actinobacteria,4DHC4@85008|Micromonosporales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
ZZS2_k127_3300337_15	756067.MicvaDRAFT_2450	7.799e-06	57.0	COG0438@1|root,COG0457@1|root,COG0463@1|root,COG2518@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0463@2|Bacteria,COG2518@2|Bacteria,1GR5V@1117|Cyanobacteria	1117|Cyanobacteria	H	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11,Methyltransf_21
ZZS2_k127_3300337_10	1122137.AQXF01000004_gene1777	1.844e-31	134.0	COG0500@1|root,COG0500@2|Bacteria,1N42B@1224|Proteobacteria,2US87@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ZZS2_k127_3300337_0	497964.CfE428DRAFT_3901	2.176e-233	740.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS2_k127_3300337_6	452637.Oter_3080	1.404e-66	237.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
ZZS2_k127_330847_14	1122947.FR7_2833	0.0001416	44.0	COG0546@1|root,COG0546@2|Bacteria,1V5HQ@1239|Firmicutes,4H4DM@909932|Negativicutes	909932|Negativicutes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2,Hydrolase_like
ZZS2_k127_330847_0	1123508.JH636446_gene6232	5.759e-200	640.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS2_k127_330847_2	1403819.BATR01000185_gene6430	7.277e-110	405.0	COG3121@1|root,COG3204@1|root,COG3291@1|root,COG3506@1|root,COG5184@1|root,COG3121@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_330847_7	1278073.MYSTI_05030	1.59e-40	176.0	COG3055@1|root,COG5563@1|root,COG3055@2|Bacteria,COG5563@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria,2YYIK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1
ZZS2_k127_330847_12	338969.Rfer_0682	2.928e-07	66.0	COG3468@1|root,COG5295@1|root,COG3468@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF3494,He_PIG
ZZS2_k127_330847_4	1121897.AUGO01000002_gene2177	1.872e-60	242.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_330847_1	497964.CfE428DRAFT_4485	2.087e-130	430.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_330847_5	1122134.KB893651_gene2010	8.833e-44	163.0	2CNK3@1|root,31TH7@2|Bacteria,1R38H@1224|Proteobacteria,1S7X7@1236|Gammaproteobacteria,1XKY6@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
ZZS2_k127_330847_6	886293.Sinac_5702	1.177e-41	168.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
ZZS2_k127_330847_11	56780.SYN_01127	1.046e-07	65.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_330847_10	243231.GSU0891	7.838e-11	76.0	COG1361@1|root,COG1404@1|root,COG5549@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG5549@2|Bacteria,1RC5K@1224|Proteobacteria,42U2I@68525|delta/epsilon subdivisions,2WQAT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_330847_13	1131814.JAFO01000001_gene2160	8.732e-06	59.0	COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2U7KA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
ZZS2_k127_330847_8	189426.PODO_17430	5.578e-37	148.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS2_k127_330847_9	1396141.BATP01000036_gene3813	3.277e-35	139.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
ZZS2_k127_330847_3	1340493.JNIF01000003_gene3428	1.024e-83	284.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS2_k127_3309372_8	497964.CfE428DRAFT_1239	6.998e-68	242.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3309372_1	497964.CfE428DRAFT_1238	5.521e-243	755.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_3309372_0	497964.CfE428DRAFT_1237	1.129e-246	769.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_3309372_7	479434.Sthe_1382	1.594e-74	271.0	COG0434@1|root,COG0434@2|Bacteria,2G6UF@200795|Chloroflexi,27Y89@189775|Thermomicrobia	189775|Thermomicrobia	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
ZZS2_k127_3309372_6	1267534.KB906755_gene4489	2.238e-82	289.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
ZZS2_k127_3309372_4	661478.OP10G_2908	1.133e-111	371.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
ZZS2_k127_3309372_9	671143.DAMO_2133	1.167e-45	179.0	COG0845@1|root,COG0845@2|Bacteria,2NPNY@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	ybhG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_3309372_3	452637.Oter_0314	1.241e-120	413.0	COG5373@1|root,COG5373@2|Bacteria,46UM1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
ZZS2_k127_3309372_2	497964.CfE428DRAFT_1104	3.231e-239	774.0	COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
ZZS2_k127_3309372_5	1121091.AUMP01000015_gene661	1.146e-107	359.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
ZZS2_k127_3309539_11	530564.Psta_2878	3.512e-31	128.0	COG1073@1|root,COG1073@2|Bacteria,2IXK0@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
ZZS2_k127_3309539_6	1396418.BATQ01000067_gene1672	2.207e-85	286.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase,Polyketide_cyc2
ZZS2_k127_3309539_12	661478.OP10G_4295	0.000176	44.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8,Pro-kuma_activ
ZZS2_k127_3309539_2	497964.CfE428DRAFT_6538	3.392e-131	429.0	COG0500@1|root,COG0500@2|Bacteria,46Z8Z@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
ZZS2_k127_3309539_3	886293.Sinac_4427	9.116e-123	408.0	COG3023@1|root,COG3023@2|Bacteria,2J257@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
ZZS2_k127_3309539_10	478741.JAFS01000001_gene1519	1.044e-35	137.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
ZZS2_k127_3309539_5	1158338.JNLJ01000001_gene1214	1.616e-95	326.0	COG2804@1|root,COG2804@2|Bacteria,2G4H7@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
ZZS2_k127_3309539_4	243233.MCA1632	5.556e-108	380.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales	135618|Methylococcales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
ZZS2_k127_3309539_9	879212.DespoDRAFT_01625	1.03e-41	161.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42W76@68525|delta/epsilon subdivisions,2WSHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
ZZS2_k127_3309539_0	1123508.JH636439_gene599	1.311e-310	979.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_3309539_1	1210884.HG799463_gene9924	9.668e-221	719.0	COG2133@1|root,COG3474@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3474@2|Bacteria,COG3828@2|Bacteria,2J124@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3309539_7	794903.OPIT5_13235	6.857e-71	244.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
ZZS2_k127_3309539_8	1396418.BATQ01000176_gene2697	1.91e-46	173.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin,TraF
ZZS2_k127_3311658_6	37659.JNLN01000001_gene924	8.713e-19	87.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,36EP1@31979|Clostridiaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
ZZS2_k127_3311658_3	1396418.BATQ01000044_gene6450	8.039e-90	302.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
ZZS2_k127_3311658_8	879212.DespoDRAFT_03364	6.292e-08	65.0	COG5338@1|root,COG5338@2|Bacteria,1QTI0@1224|Proteobacteria,42PG4@68525|delta/epsilon subdivisions,2WKB2@28221|Deltaproteobacteria,2MJF0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
ZZS2_k127_3311658_0	1396141.BATP01000005_gene5989	0.0	1157.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
ZZS2_k127_3311658_1	756272.Plabr_3182	6.985e-184	593.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_3311658_2	344747.PM8797T_14319	2.767e-93	320.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_3311658_5	1046625.AFQY01000002_gene1440	3.028e-21	102.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,3NN5T@468|Moraxellaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS2_k127_3311658_10	287.DR97_1854	5.196e-06	57.0	COG4970@1|root,COG4970@2|Bacteria,1N43I@1224|Proteobacteria,1SBWS@1236|Gammaproteobacteria,1YH03@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
ZZS2_k127_3311658_9	344747.PM8797T_14299	5.811e-07	60.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_3311658_4	344747.PM8797T_14294	6.326e-42	174.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
ZZS2_k127_3311658_11	272134.KB731324_gene4649	4.13e-05	56.0	COG4972@1|root,COG4972@2|Bacteria,1G0A3@1117|Cyanobacteria,1H7GE@1150|Oscillatoriales	1117|Cyanobacteria	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS2_k127_3311658_7	344747.PM8797T_14329	4.431e-14	87.0	COG1450@1|root,COG1450@2|Bacteria,2IYKG@203682|Planctomycetes	203682|Planctomycetes	NU	Bacterial type II/III secretion system short domain	-	-	-	-	-	-	-	-	-	-	-	-	Secretin_N
ZZS2_k127_3332606_0	479432.Sros_4819	6.678e-266	835.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4ENBU@85012|Streptosporangiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
ZZS2_k127_3332606_3	397291.C804_00922	9.067e-21	98.0	COG3415@1|root,COG3415@2|Bacteria,1W68Z@1239|Firmicutes,255YR@186801|Clostridia,27R45@186928|unclassified Lachnospiraceae	2|Bacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
ZZS2_k127_3332606_4	1123065.ATWL01000006_gene2347	3.578e-16	83.0	COG1848@1|root,COG1848@2|Bacteria,2IKT8@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
ZZS2_k127_3332606_2	278957.ABEA03000046_gene1614	1.707e-86	293.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
ZZS2_k127_3332606_5	1110502.TMO_3150	7.556e-15	84.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,2U9N6@28211|Alphaproteobacteria,2JSQS@204441|Rhodospirillales	204441|Rhodospirillales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
ZZS2_k127_3332606_1	1173022.Cri9333_3705	4.226e-102	367.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1G09B@1117|Cyanobacteria,1HEES@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_3335664_2	469383.Cwoe_5474	3.505e-13	83.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_1
ZZS2_k127_3335664_3	1122225.AULQ01000001_gene1591	1.611e-10	74.0	COG4886@1|root,COG4886@2|Bacteria,4PM1T@976|Bacteroidetes,1HWWE@117743|Flavobacteriia	976|Bacteroidetes	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3335664_4	1235803.C825_03072	5.342e-09	70.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,22X5K@171551|Porphyromonadaceae	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
ZZS2_k127_3335664_0	1381123.AYOD01000035_gene3383	9.479e-103	342.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,43JQZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	hpcH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0008150,GO:0008152,GO:0016829,GO:0016830,GO:0016832,GO:0044238,GO:0044424,GO:0044464,GO:0071704	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS2_k127_3335664_1	314230.DSM3645_02263	3.257e-69	250.0	COG2271@1|root,COG2271@2|Bacteria,2IZV2@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
ZZS2_k127_3337100_9	411470.RUMGNA_02960	1.978e-27	111.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia,3Y1PT@572511|Blautia	186801|Clostridia	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3337100_11	1122182.KB903814_gene2883	2.429e-13	85.0	COG3209@1|root,COG3534@1|root,COG3209@2|Bacteria,COG3534@2|Bacteria,2I35N@201174|Actinobacteria	201174|Actinobacteria	M	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_3337100_8	886377.Murru_3307	4.176e-42	162.0	COG3291@1|root,COG3291@2|Bacteria,4NH7R@976|Bacteroidetes,1IJC3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_3337100_7	1396418.BATQ01000007_gene1419	9.671e-62	222.0	COG3828@1|root,COG3828@2|Bacteria,46UCF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_3337100_6	986075.CathTA2_1853	2.847e-85	288.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli	91061|Bacilli	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
ZZS2_k127_3337100_2	886293.Sinac_3844	3.426e-117	407.0	COG0457@1|root,COG2755@1|root,COG0457@2|Bacteria,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N,Lipase_GDSL_2,SLH,TPR_16,TPR_19,fn3
ZZS2_k127_3337100_10	1156937.MFUM_260026	3.665e-25	113.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,37H9P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
ZZS2_k127_3337100_5	497964.CfE428DRAFT_0873	3.224e-86	302.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
ZZS2_k127_3337100_3	1156937.MFUM_700041	8.747e-107	356.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,37G2R@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS2_k127_3337100_4	497964.CfE428DRAFT_0870	2.922e-90	308.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
ZZS2_k127_3337100_0	521674.Plim_1120	1.932e-286	900.0	COG2010@1|root,COG2010@2|Bacteria,2IXTE@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_3337100_1	344747.PM8797T_02914	2.425e-202	646.0	COG3119@1|root,COG3119@2|Bacteria,2IXE5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_3339092_7	1380387.JADM01000007_gene818	2.069e-38	147.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1SDPW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_3339092_1	240016.ABIZ01000001_gene2056	4.67e-196	624.0	COG0644@1|root,COG0644@2|Bacteria,46TJ0@74201|Verrucomicrobia,2IV4G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
ZZS2_k127_3339092_9	481448.Minf_2472	5.044e-11	71.0	2BFQ8@1|root,329IT@2|Bacteria,46YZG@74201|Verrucomicrobia,37GUA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3339092_3	648996.Theam_1309	3.376e-81	280.0	COG0414@1|root,COG0414@2|Bacteria,2G3TD@200783|Aquificae	200783|Aquificae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
ZZS2_k127_3339092_0	290397.Adeh_3566	9.333e-199	632.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS2_k127_3339092_10	83406.HDN1F_30540	6.757e-11	76.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
ZZS2_k127_3339092_11	243090.RB4375	8.136e-10	72.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF642
ZZS2_k127_3339092_8	83406.HDN1F_04070	7.793e-38	164.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein D	xcpQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	SPOR,Secretin,Secretin_N
ZZS2_k127_3339092_13	794903.OPIT5_16210	0.0005042	52.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_3339092_2	1123508.JH636439_gene1319	1.066e-146	484.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_3339092_5	1165841.SULAR_01175	1.842e-45	174.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
ZZS2_k127_3339092_6	452637.Oter_1801	1.03e-42	169.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,46W2T@74201|Verrucomicrobia,3K80B@414999|Opitutae	414999|Opitutae	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
ZZS2_k127_3339092_4	926562.Oweho_2291	1.431e-52	207.0	COG2931@1|root,COG4222@1|root,COG2931@2|Bacteria,COG4222@2|Bacteria,4NKF1@976|Bacteroidetes,1II60@117743|Flavobacteriia,2PBH9@246874|Cryomorphaceae	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
ZZS2_k127_3339092_12	485918.Cpin_4405	8.904e-06	59.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IVAH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
ZZS2_k127_3340136_3	1122603.ATVI01000012_gene1134	1.434e-49	205.0	COG1404@1|root,COG2373@1|root,COG1404@2|Bacteria,COG2373@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,PPC,P_proprotein,Peptidase_S8
ZZS2_k127_3340136_2	1123057.P872_14365	2.495e-71	277.0	COG3386@1|root,COG4733@1|root,COG3386@2|Bacteria,COG4733@2|Bacteria,4NIJT@976|Bacteroidetes,47XYW@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5008,DUF5122
ZZS2_k127_3340136_1	234267.Acid_4124	3.554e-102	379.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
ZZS2_k127_3340136_0	497964.CfE428DRAFT_0327	2.024e-112	404.0	COG1361@1|root,COG1404@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4733@2|Bacteria,46UDB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5122
ZZS2_k127_3340136_4	469383.Cwoe_4932	0.0003382	55.0	COG3291@1|root,COG3291@2|Bacteria,2HP4G@201174|Actinobacteria,4CQG0@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394
ZZS2_k127_3343203_15	530564.Psta_2904	5.622e-11	67.0	COG2146@1|root,COG2146@2|Bacteria,2J0FX@203682|Planctomycetes	203682|Planctomycetes	P	COG2146 Ferredoxin subunits of nitrite reductase and	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
ZZS2_k127_3343203_16	1156937.MFUM_930022	8.937e-10	66.0	COG3063@1|root,COG3063@2|Bacteria,46T56@74201|Verrucomicrobia,37GXT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PPR,TPR_11,TPR_2,TPR_8
ZZS2_k127_3343203_9	497964.CfE428DRAFT_4443	3.774e-52	195.0	COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
ZZS2_k127_3343203_0	497964.CfE428DRAFT_4284	4.999e-270	844.0	COG0674@1|root,COG0674@2|Bacteria,46SM9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
ZZS2_k127_3343203_3	497964.CfE428DRAFT_4282	2.25e-153	490.0	COG1013@1|root,COG1013@2|Bacteria,46SRY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
ZZS2_k127_3343203_11	472759.Nhal_3762	1.074e-32	133.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,1S6XI@1236|Gammaproteobacteria,1WYMU@135613|Chromatiales	135613|Chromatiales	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS2_k127_3343203_13	497964.CfE428DRAFT_4444	7.364e-16	80.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3343203_2	382464.ABSI01000012_gene2146	1.57e-172	561.0	COG1593@1|root,COG1593@2|Bacteria	2|Bacteria	G	mannitol 2-dehydrogenase activity	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM,DctQ
ZZS2_k127_3343203_6	1304883.KI912532_gene2773	5.595e-85	295.0	COG1638@1|root,COG1638@2|Bacteria,1PMWE@1224|Proteobacteria,2VNJI@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS2_k127_3343203_5	335543.Sfum_2673	1.188e-91	313.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
ZZS2_k127_3343203_1	497964.CfE428DRAFT_3032	1.031e-186	596.0	COG1109@1|root,COG1109@2|Bacteria,46SJ2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS2_k127_3343203_8	1396418.BATQ01000056_gene232	6.713e-55	203.0	COG1624@1|root,COG1624@2|Bacteria,46SSQ@74201|Verrucomicrobia,2IU56@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DisA bacterial checkpoint controller nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
ZZS2_k127_3343203_7	497964.CfE428DRAFT_3030	4.022e-76	265.0	COG0294@1|root,COG0294@2|Bacteria,46SSW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
ZZS2_k127_3343203_10	945713.IALB_2065	6.587e-42	166.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK
ZZS2_k127_3343203_12	1396141.BATP01000023_gene490	5.066e-19	91.0	2C1W8@1|root,2ZXK7@2|Bacteria,46WJJ@74201|Verrucomicrobia,2IUVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS2_k127_3343203_19	693444.D782_3890	2.823e-05	53.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,283P2@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
ZZS2_k127_3343203_17	452637.Oter_1161	3.148e-09	62.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
ZZS2_k127_3343203_14	595460.RRSWK_00476	1.555e-11	66.0	COG5487@1|root,COG5487@2|Bacteria,2J16P@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
ZZS2_k127_3343203_4	247490.KSU1_C0880	2.651e-96	323.0	COG0005@1|root,COG0005@2|Bacteria,2IZAA@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
ZZS2_k127_3343203_18	1267534.KB906758_gene2500	1.708e-05	52.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,VCBS
ZZS2_k127_3348382_18	1123508.JH636441_gene3436	7.093e-60	228.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_3348382_5	1278073.MYSTI_07720	5.539e-176	562.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2WNNB@28221|Deltaproteobacteria,2YUAE@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
ZZS2_k127_3348382_8	1183438.GKIL_0560	1.881e-137	456.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
ZZS2_k127_3348382_17	272558.10172616	3.968e-62	228.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
ZZS2_k127_3348382_14	1068978.AMETH_2314	3.591e-82	280.0	COG0584@1|root,COG0584@2|Bacteria,2GIY5@201174|Actinobacteria,4DYQX@85010|Pseudonocardiales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD_2
ZZS2_k127_3348382_27	452637.Oter_0300	1.528e-25	116.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF3379
ZZS2_k127_3348382_22	1123070.KB899256_gene2167	1.77e-42	164.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia,2IUIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3348382_20	330214.NIDE3859	1.918e-47	174.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS2_k127_3348382_2	481448.Minf_1144	1.612e-214	686.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,37G3T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
ZZS2_k127_3348382_35	316067.Geob_1811	1.939e-07	61.0	2F788@1|root,33ZPH@2|Bacteria,1NZCH@1224|Proteobacteria,430NT@68525|delta/epsilon subdivisions,2WVSK@28221|Deltaproteobacteria,43VB2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
ZZS2_k127_3348382_33	314230.DSM3645_09507	4.509e-09	68.0	2AZY1@1|root,31S7T@2|Bacteria,2IZYE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3348382_29	261292.Nit79A3_2553	2.294e-20	104.0	2AZY1@1|root,31S7T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3348382_11	278957.ABEA03000091_gene714	6.568e-104	346.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
ZZS2_k127_3348382_6	497964.CfE428DRAFT_1869	3.515e-175	556.0	COG1899@1|root,COG1899@2|Bacteria,46T9G@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
ZZS2_k127_3348382_16	483219.LILAB_27650	5.929e-75	267.0	COG2374@1|root,COG2374@2|Bacteria,1RA34@1224|Proteobacteria,42XZM@68525|delta/epsilon subdivisions,2WT9C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
ZZS2_k127_3348382_37	627192.SLG_03040	2.816e-05	56.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2TTRG@28211|Alphaproteobacteria,2K10D@204457|Sphingomonadales	204457|Sphingomonadales	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_3348382_21	690850.Desaf_3350	1.116e-45	183.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2M8WT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
ZZS2_k127_3348382_9	596152.DesU5LDRAFT_2668	3.988e-134	441.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8VA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_3348382_13	452637.Oter_0908	4.227e-94	321.0	COG0697@1|root,COG0697@2|Bacteria,46VIK@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_3348382_3	861299.J421_5606	5.748e-214	674.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_3348382_1	62928.azo0088	7.035e-300	955.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,2KVBJ@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS2_k127_3348382_0	497964.CfE428DRAFT_4764	1.833e-302	952.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS2_k127_3348382_12	452637.Oter_2237	1.552e-102	343.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_3348382_32	452637.Oter_2236	1.548e-11	65.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
ZZS2_k127_3348382_31	344747.PM8797T_04035	6.071e-15	90.0	COG3250@1|root,COG3250@2|Bacteria,2J3T5@203682|Planctomycetes	203682|Planctomycetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3348382_36	72228.T5A7U6	2.71e-07	65.0	KOG0291@1|root,KOG0291@2759|Eukaryota,38DVV@33154|Opisthokonta,3NVZP@4751|Fungi,3QMAJ@4890|Ascomycota,217PV@147550|Sordariomycetes,3TDTB@5125|Hypocreales	4751|Fungi	A	Periodic tryptophan protein 2	PWP2	GO:0000028,GO:0000447,GO:0000460,GO:0000462,GO:0000466,GO:0000469,GO:0000472,GO:0000478,GO:0000479,GO:0000480,GO:0000920,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007163,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030010,GO:0030490,GO:0030515,GO:0030684,GO:0030686,GO:0031974,GO:0031981,GO:0032040,GO:0032991,GO:0034388,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0051301,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K14558	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Utp12,WD40
ZZS2_k127_3348382_15	382464.ABSI01000011_gene2968	8.526e-82	309.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3348382_19	497964.CfE428DRAFT_0064	4.709e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_3348382_26	1123508.JH636442_gene4323	1.024e-25	125.0	COG4409@1|root,COG4932@1|root,COG4409@2|Bacteria,COG4932@2|Bacteria,2J4JQ@203682|Planctomycetes	203682|Planctomycetes	M	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3348382_4	497964.CfE428DRAFT_4471	2.534e-185	596.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,DUF4396
ZZS2_k127_3348382_28	1385935.N836_13145	2.291e-21	113.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3348382_24	153721.MYP_2462	7.472e-32	147.0	COG2730@1|root,COG3325@1|root,COG3469@1|root,COG5295@1|root,COG2730@2|Bacteria,COG3325@2|Bacteria,COG3469@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
ZZS2_k127_3348382_30	1443665.JACA01000017_gene4583	2.077e-15	93.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Reprolysin_4,YadA_anchor,YadA_stalk
ZZS2_k127_3348382_10	425104.Ssed_1747	3.028e-113	417.0	COG0366@1|root,COG1409@1|root,COG0366@2|Bacteria,COG1409@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
ZZS2_k127_3348382_25	864051.BurJ1DRAFT_0895	8.937e-26	127.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
ZZS2_k127_3348382_38	1120972.AUMH01000013_gene2414	3.448e-05	53.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox,Uma2
ZZS2_k127_3348382_7	886293.Sinac_2617	1.474e-148	506.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
ZZS2_k127_3348382_23	1122179.KB890442_gene1152	1.875e-40	164.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_3367917_4	1123073.KB899241_gene3250	1.761e-61	214.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
ZZS2_k127_3367917_1	1396858.Q666_10270	1.44e-90	308.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
ZZS2_k127_3367917_13	1123277.KB893210_gene2862	1.686e-10	70.0	29Q3N@1|root,30B2B@2|Bacteria,4NPCV@976|Bacteroidetes,47Q0V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3367917_10	1266925.JHVX01000001_gene2468	5.424e-18	84.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2W8JG@28216|Betaproteobacteria,373T2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3367917_9	278957.ABEA03000005_gene4416	1.551e-20	92.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
ZZS2_k127_3367917_0	794903.OPIT5_27320	2.092e-91	314.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS2_k127_3367917_11	583355.Caka_1460	9.626e-14	83.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46V3K@74201|Verrucomicrobia,3KA28@414999|Opitutae	414999|Opitutae	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
ZZS2_k127_3367917_8	306281.AJLK01000189_gene1779	2.958e-21	99.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1JIY9@1189|Stigonemataceae	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_3367917_6	1122609.AUGT01000008_gene2868	4.607e-44	186.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
ZZS2_k127_3367917_12	330214.NIDE0059	1.163e-12	68.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3J1E4@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	Rhodanese,SNARE_assoc
ZZS2_k127_3367917_2	330214.NIDE0059	1.964e-71	254.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3J1E4@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	Rhodanese,SNARE_assoc
ZZS2_k127_3367917_5	1227739.Hsw_3872	1.665e-55	211.0	COG4859@1|root,COG4859@2|Bacteria,4PKK7@976|Bacteroidetes	976|Bacteroidetes	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU,TPR_1,TPR_2
ZZS2_k127_3367917_7	1288494.EBAPG3_12100	2.095e-22	101.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2VJBD@28216|Betaproteobacteria,372I3@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DUF1080,FAD_binding_2,GMC_oxred_C
ZZS2_k127_3367917_3	319003.Bra1253DRAFT_02062	1.253e-66	232.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria,3JSC8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3371512_4	1121904.ARBP01000015_gene230	5.299e-137	441.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
ZZS2_k127_3371512_0	886293.Sinac_3589	0.0	1205.0	COG2010@1|root,COG2010@2|Bacteria,2IX6S@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
ZZS2_k127_3371512_2	886293.Sinac_3588	1.724e-224	702.0	COG2960@1|root,COG2960@2|Bacteria,2IX5N@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_3371512_3	234267.Acid_0930	1.05e-198	628.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_3371512_1	234267.Acid_0929	0.0	1161.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
ZZS2_k127_3371512_5	1396141.BATP01000022_gene486	3.733e-119	410.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
ZZS2_k127_3381667_0	1267535.KB906767_gene2985	4.976e-198	634.0	COG0577@1|root,COG0577@2|Bacteria,3Y38T@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_3381667_2	452637.Oter_1641	1.142e-36	145.0	2CCSR@1|root,32RWC@2|Bacteria,46WYJ@74201|Verrucomicrobia,3K9ZP@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS2_k127_3381667_1	861299.J421_6226	4.476e-45	173.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_338925_1	1396141.BATP01000003_gene4934	2.17e-69	265.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_338925_3	755732.Fluta_1212	1.485e-36	160.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_338925_0	317936.Nos7107_4863	4.342e-171	552.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
ZZS2_k127_338925_2	869210.Marky_1176	2.787e-54	195.0	COG1225@1|root,COG1225@2|Bacteria,1WI9E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS2_k127_3418586_9	207559.Dde_2842	3.015e-28	124.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,2MAB9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
ZZS2_k127_3418586_11	1123371.ATXH01000018_gene1408	4.605e-09	60.0	COG2331@1|root,COG2331@2|Bacteria,2GI34@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS2_k127_3418586_0	1472716.KBK24_0120605	0.0	1198.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,1K184@119060|Burkholderiaceae	28216|Betaproteobacteria	O	type VI secretion ATPase, ClpV1 family	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS2_k127_3418586_4	530564.Psta_1837	7.018e-97	327.0	COG3520@1|root,COG3520@2|Bacteria,2IZ33@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, VC_A0111 family	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
ZZS2_k127_3418586_3	497964.CfE428DRAFT_2840	3.976e-250	787.0	COG3519@1|root,COG3519@2|Bacteria,46TGI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system, TssF	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_TssF
ZZS2_k127_3418586_7	497964.CfE428DRAFT_2839	1.082e-37	148.0	COG3518@1|root,COG3518@2|Bacteria,46WW6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Gene 25-like lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	GPW_gp25
ZZS2_k127_3418586_5	497964.CfE428DRAFT_2838	2.553e-93	314.0	COG4455@1|root,COG4455@2|Bacteria,46VF7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImpE protein	-	-	-	-	-	-	-	-	-	-	-	-	ImpE
ZZS2_k127_3418586_8	234267.Acid_0233	3.466e-36	142.0	COG3157@1|root,COG3157@2|Bacteria,3Y5QP@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
ZZS2_k127_3418586_2	765913.ThidrDRAFT_2282	4.3e-254	790.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1WXN1@135613|Chromatiales	135613|Chromatiales	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
ZZS2_k127_3418586_6	497964.CfE428DRAFT_2834	4.957e-85	285.0	COG3516@1|root,COG3516@2|Bacteria,46VI5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA
ZZS2_k127_3418586_1	448385.sce0958	6.093e-264	847.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
ZZS2_k127_3418586_10	525904.Tter_1676	6.193e-15	77.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS2_k127_3429037_7	1396418.BATQ01000166_gene1868	2.13e-93	310.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
ZZS2_k127_3429037_18	644283.Micau_1136	1.632e-14	87.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3429037_20	103733.JNYO01000054_gene2316	1.83e-08	67.0	COG5297@1|root,COG5297@2|Bacteria,2I2T2@201174|Actinobacteria,4DY4F@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 48	celY	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_3,Glyco_hydro_48,fn3
ZZS2_k127_3429037_16	543632.JOJL01000005_gene4835	2.953e-19	102.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3429037_14	1122915.AUGY01000075_gene3132	2.645e-34	150.0	COG3401@1|root,COG3664@1|root,COG3401@2|Bacteria,COG3664@2|Bacteria,1VTGP@1239|Firmicutes,4HV8E@91061|Bacilli,26VFN@186822|Paenibacillaceae	91061|Bacilli	G	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_cc
ZZS2_k127_3429037_3	1210884.HG799464_gene11111	8.021e-165	524.0	COG1402@1|root,COG1402@2|Bacteria,2IYP1@203682|Planctomycetes	203682|Planctomycetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
ZZS2_k127_3429037_8	452637.Oter_2672	4.618e-83	295.0	COG2271@1|root,COG2271@2|Bacteria,46UQA@74201|Verrucomicrobia,3K8MQ@414999|Opitutae	414999|Opitutae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_3429037_2	1267535.KB906767_gene4072	2.147e-184	582.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_3429037_1	616991.JPOO01000001_gene4502	2.138e-212	669.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,1HYAT@117743|Flavobacteriia,23G1H@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
ZZS2_k127_3429037_17	452637.Oter_1864	1.902e-17	87.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
ZZS2_k127_3429037_11	497964.CfE428DRAFT_4864	1.017e-57	211.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3429037_10	497964.CfE428DRAFT_5952	1.353e-70	248.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_3429037_4	497964.CfE428DRAFT_5953	8.568e-112	384.0	COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_3429037_6	497964.CfE428DRAFT_3302	1.647e-96	330.0	29ZE1@1|root,30MD7@2|Bacteria,46VK4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3429037_5	335543.Sfum_1617	1.283e-105	365.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_3429037_19	1254432.SCE1572_11040	8.218e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSCX@28221|Deltaproteobacteria,2YZCB@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_2,TPR_8
ZZS2_k127_3429037_0	1403819.BATR01000042_gene1245	1.065e-235	751.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
ZZS2_k127_3429037_12	1403819.BATR01000177_gene5956	2.23e-51	185.0	COG0346@1|root,COG0346@2|Bacteria,46SUF@74201|Verrucomicrobia,2IUKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_3429037_13	1120965.AUBV01000001_gene3356	5.821e-35	137.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,47QQ7@768503|Cytophagia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
ZZS2_k127_3429037_15	497964.CfE428DRAFT_4747	6.171e-29	124.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
ZZS2_k127_3429037_9	944481.JAFP01000001_gene621	2.428e-71	247.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42RAF@68525|delta/epsilon subdivisions,2WN7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Site-specific DNA-methyltransferase (Adenine-specific)	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
ZZS2_k127_3460108_3	497964.CfE428DRAFT_2513	1.612e-147	478.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_3460108_7	497964.CfE428DRAFT_4931	4.741e-59	221.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
ZZS2_k127_3460108_8	1396141.BATP01000061_gene4485	3.842e-44	165.0	COG1327@1|root,COG1327@2|Bacteria,46TAA@74201|Verrucomicrobia,2IU77@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
ZZS2_k127_3460108_15	1123070.KB899256_gene2169	0.0004732	49.0	28XDJ@1|root,2ZJBA@2|Bacteria,46WSJ@74201|Verrucomicrobia,2IUQ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3460108_9	2903.EOD22473	1.502e-42	158.0	COG0537@1|root,KOG3275@2759|Eukaryota	2759|Eukaryota	FG	nucleoside phosphate binding	HINT1	GO:0000118,GO:0003674,GO:0003824,GO:0005080,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010646,GO:0010647,GO:0012501,GO:0016020,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0023051,GO:0023052,GO:0023056,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035556,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050848,GO:0050850,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0071944,GO:0072331,GO:0072332,GO:0072521,GO:0072523,GO:0080090,GO:0097190,GO:0097193,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902494,GO:1902531,GO:1902533,GO:1903506,GO:2000112,GO:2001141	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	iRC1080.CRv4_Au5_s6_g12858_t1	HIT
ZZS2_k127_3460108_5	335543.Sfum_1870	3.943e-128	436.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
ZZS2_k127_3460108_6	1313301.AUGC01000012_gene1341	2.865e-87	295.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_3460108_10	583355.Caka_2304	4.749e-40	164.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
ZZS2_k127_3460108_1	344747.PM8797T_29842	3.113e-212	681.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
ZZS2_k127_3460108_12	1121033.AUCF01000020_gene699	8.966e-35	143.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yqfZ	-	-	-	-	-	-	-	-	-	-	-	LysM
ZZS2_k127_3460108_4	197221.22296007	1.09e-129	439.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria	1117|Cyanobacteria	T	Transmembrane sensor domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_3460108_2	330214.NIDE0551	1.249e-163	543.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
ZZS2_k127_3460108_0	1396418.BATQ01000127_gene2553	2.746e-252	791.0	COG0659@1|root,COG2066@1|root,COG0659@2|Bacteria,COG2066@2|Bacteria,46USD@74201|Verrucomicrobia,2ITM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Glutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Glutaminase,cNMP_binding
ZZS2_k127_3460108_13	1121935.AQXX01000124_gene95	4.76e-12	72.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1XRB8@135619|Oceanospirillales	135619|Oceanospirillales	T	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS2_k127_3460108_11	498848.TaqDRAFT_4878	1.066e-36	154.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3465722_25	530564.Psta_0838	4.608e-18	87.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
ZZS2_k127_3465722_20	497964.CfE428DRAFT_0984	1.785e-46	174.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_3465722_24	452637.Oter_1277	3.731e-18	94.0	COG4191@1|root,COG4191@2|Bacteria,46Z7N@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
ZZS2_k127_3465722_8	240016.ABIZ01000001_gene5374	7.108e-151	489.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_3465722_37	1230342.CTM_01385	0.0001758	50.0	COG1579@1|root,COG1579@2|Bacteria,1VKTP@1239|Firmicutes,24JFI@186801|Clostridia,36JGI@31979|Clostridiaceae	186801|Clostridia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
ZZS2_k127_3465722_34	1408438.JADD01000029_gene1367	5.096e-06	55.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,27ECC@186827|Aerococcaceae	91061|Bacilli	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
ZZS2_k127_3465722_28	452637.Oter_1279	8.566e-11	67.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
ZZS2_k127_3465722_27	224914.BMEI1786	3.124e-12	74.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,1J2C6@118882|Brucellaceae	28211|Alphaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
ZZS2_k127_3465722_18	240016.ABIZ01000001_gene2769	4.966e-66	232.0	COG4123@1|root,COG4123@2|Bacteria,46VM2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_3465722_17	452637.Oter_1277	3.735e-76	263.0	COG4191@1|root,COG4191@2|Bacteria,46Z7N@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
ZZS2_k127_3465722_7	497964.CfE428DRAFT_3753	1.243e-152	498.0	COG2204@1|root,COG2204@2|Bacteria,46S87@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_3465722_38	1172190.M947_06755	0.0008041	47.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
ZZS2_k127_3465722_29	309798.COPRO5265_1343	1.963e-10	70.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,42GZ3@68295|Thermoanaerobacterales	186801|Clostridia	G	phosphocarrier	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ZZS2_k127_3465722_35	452637.Oter_1279	5.398e-06	56.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
ZZS2_k127_3465722_30	1121091.AUMP01000013_gene3281	1.955e-07	62.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli	91061|Bacilli	G	phosphotransferase system	manP	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	iSB619.SA_RS13955	PTS_EIIA_2,PTS_EIIC,PTS_IIB
ZZS2_k127_3465722_22	1156937.MFUM_990021	2.665e-24	117.0	COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,37FYI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Pyruvate kinase, alpha/beta domain	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
ZZS2_k127_3465722_26	452637.Oter_1279	1.246e-16	85.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
ZZS2_k127_3465722_32	1400520.LFAB_16230	6.693e-07	60.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae	91061|Bacilli	GT	Phosphotransferase System	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
ZZS2_k127_3465722_1	452637.Oter_2456	5.111e-291	905.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	414999|Opitutae	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
ZZS2_k127_3465722_13	278957.ABEA03000117_gene1100	5.226e-93	310.0	COG1762@1|root,COG1762@2|Bacteria,46YU0@74201|Verrucomicrobia,3K7XN@414999|Opitutae	414999|Opitutae	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
ZZS2_k127_3465722_2	794903.OPIT5_19305	1.343e-287	896.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	414999|Opitutae	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
ZZS2_k127_3465722_10	794903.OPIT5_19300	2.932e-136	441.0	COG0650@1|root,COG0650@2|Bacteria,46V7E@74201|Verrucomicrobia,3K7BZ@414999|Opitutae	414999|Opitutae	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
ZZS2_k127_3465722_14	278957.ABEA03000117_gene1097	9.71e-91	312.0	COG4237@1|root,COG4237@2|Bacteria,46XG2@74201|Verrucomicrobia,3K771@414999|Opitutae	414999|Opitutae	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
ZZS2_k127_3465722_4	452637.Oter_2459	1.462e-231	731.0	COG0651@1|root,COG0651@2|Bacteria,46YVS@74201|Verrucomicrobia,3K981@414999|Opitutae	414999|Opitutae	CP	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
ZZS2_k127_3465722_3	794903.OPIT5_19285	7.819e-252	794.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,46TQW@74201|Verrucomicrobia,3K7GA@414999|Opitutae	414999|Opitutae	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
ZZS2_k127_3465722_11	794903.OPIT5_19275	2.865e-128	413.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,46VST@74201|Verrucomicrobia,3K7DE@414999|Opitutae	414999|Opitutae	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Oxidored_q6
ZZS2_k127_3465722_33	331869.BAL199_24289	1.046e-06	53.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VC8M@28211|Alphaproteobacteria,4BSKF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3465722_6	1123277.KB893217_gene4678	8.175e-215	677.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
ZZS2_k127_3465722_0	945713.IALB_3112	0.0	1157.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
ZZS2_k127_3465722_5	1123508.JH636441_gene3449	9.077e-224	706.0	COG1233@1|root,COG1233@2|Bacteria,2IX17@203682|Planctomycetes	203682|Planctomycetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
ZZS2_k127_3465722_9	251221.35214007	6.28e-137	445.0	COG4638@1|root,COG4638@2|Bacteria,1G6W8@1117|Cyanobacteria	1117|Cyanobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS2_k127_3465722_15	497964.CfE428DRAFT_6579	3.617e-84	280.0	COG3832@1|root,COG3832@2|Bacteria,46SRI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS2_k127_3465722_36	1396141.BATP01000030_gene3630	6.637e-06	57.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.38	ko:K00666,ko:K21909	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AP_endonuc_2,BNR_4
ZZS2_k127_3465722_21	765911.Thivi_2099	3.041e-39	170.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1QUXB@1224|Proteobacteria,1T3AY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	negative chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin,DUF4347,PATR
ZZS2_k127_3465722_12	1396141.BATP01000025_gene978	2.323e-99	359.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_3465722_16	1396141.BATP01000025_gene980	1.249e-76	262.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_3465722_31	1452535.JARD01000026_gene458	3.943e-07	63.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2I94U@201174|Actinobacteria,4FN98@85023|Microbacteriaceae	201174|Actinobacteria	K	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
ZZS2_k127_3465722_19	292459.STH2817	1.476e-57	216.0	COG1215@1|root,COG1215@2|Bacteria,1UYDS@1239|Firmicutes,25BCG@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_3465722_23	452637.Oter_0312	1.207e-18	101.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
ZZS2_k127_3465938_2	1210884.HG799465_gene12114	1.004e-55	211.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
ZZS2_k127_3465938_0	1123242.JH636436_gene130	2.787e-168	546.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_3465938_1	472759.Nhal_0193	2.378e-120	410.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
ZZS2_k127_3468821_0	1121456.ATVA01000015_gene2393	3.736e-46	184.0	28I4Y@1|root,2Z88D@2|Bacteria,1R95V@1224|Proteobacteria,42RX3@68525|delta/epsilon subdivisions,2WMGE@28221|Deltaproteobacteria,2MECJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3468821_4	198094.BA_1879	0.0004816	53.0	COG0739@1|root,COG0739@2|Bacteria,1V2IA@1239|Firmicutes,4HW9I@91061|Bacilli,1ZQTY@1386|Bacillus	91061|Bacilli	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS2_k127_3468821_2	1120965.AUBV01000005_gene1691	4.413e-12	80.0	COG0739@1|root,COG1680@1|root,COG0739@2|Bacteria,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	tagE	-	2.7.7.6	ko:K03046,ko:K21471	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03021,ko03400	-	-	-	OapA,OapA_N,Peptidase_M23,UT
ZZS2_k127_3468821_3	1122925.KB895378_gene2567	3.516e-10	73.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_3468821_1	1236976.JCM16418_4253	3.141e-12	80.0	COG1409@1|root,COG2041@1|root,COG3211@1|root,COG4733@1|root,COG1409@2|Bacteria,COG2041@2|Bacteria,COG3211@2|Bacteria,COG4733@2|Bacteria,1V7PQ@1239|Firmicutes,4IUC5@91061|Bacilli,277JF@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,SLH,fn3
ZZS2_k127_3481237_1	715451.ambt_12010	1.334e-53	205.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3481237_0	215803.DB30_8238	2.005e-73	264.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,437VX@68525|delta/epsilon subdivisions,2X35F@28221|Deltaproteobacteria,2YUCR@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_3493200_1	1236508.BAKF01000094_gene2667	9.649e-20	104.0	COG3209@1|root,COG3209@2|Bacteria,4NXFH@976|Bacteroidetes,2FZ63@200643|Bacteroidia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3493200_0	382464.ABSI01000010_gene3258	5.708e-264	853.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3498654_1	1156937.MFUM_270012	9.691e-09	56.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,37G93@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_3498654_0	1123277.KB893189_gene5243	2.644e-189	631.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
ZZS2_k127_3498654_2	338966.Ppro_2857	8.111e-08	53.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
ZZS2_k127_3508926_2	497964.CfE428DRAFT_6211	3.166e-113	376.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
ZZS2_k127_3508926_3	247490.KSU1_D0636	3.679e-19	96.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25
ZZS2_k127_3508926_1	886293.Sinac_6967	4.022e-247	769.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_3508926_0	886293.Sinac_6968	0.0	1165.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_3521946_6	416591.Tlet_1265	6.046e-22	109.0	COG0019@1|root,COG0019@2|Bacteria,2GBYB@200918|Thermotogae	200918|Thermotogae	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1517	Orn_Arg_deC_N,Orn_DAP_Arg_deC
ZZS2_k127_3521946_3	648996.Theam_0181	3.568e-140	454.0	COG0498@1|root,COG0498@2|Bacteria,2G3NU@200783|Aquificae	200783|Aquificae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC_2	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_3521946_2	452637.Oter_2235	3.815e-170	545.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
ZZS2_k127_3521946_0	1047013.AQSP01000075_gene1424	0.0	1297.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
ZZS2_k127_3521946_7	8479.XP_008161021.1	0.0001766	55.0	2CJG9@1|root,2QWRQ@2759|Eukaryota,39Q6K@33154|Opisthokonta,3BKF5@33208|Metazoa,3CVS2@33213|Bilateria,480CF@7711|Chordata,48WWE@7742|Vertebrata,4CGTT@8459|Testudines	33208|Metazoa	T	Myosin-binding protein C	MYBPC3	GO:0001671,GO:0002027,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003206,GO:0003208,GO:0003229,GO:0003231,GO:0003674,GO:0003779,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005863,GO:0006928,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007507,GO:0007517,GO:0008015,GO:0008016,GO:0008047,GO:0008092,GO:0008150,GO:0008307,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010927,GO:0014705,GO:0014706,GO:0015629,GO:0016043,GO:0016459,GO:0016460,GO:0017022,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030234,GO:0030239,GO:0031032,GO:0031033,GO:0031034,GO:0031430,GO:0031432,GO:0031672,GO:0031674,GO:0032036,GO:0032386,GO:0032501,GO:0032502,GO:0032781,GO:0032879,GO:0032970,GO:0032971,GO:0032982,GO:0032989,GO:0032991,GO:0033275,GO:0034622,GO:0036379,GO:0042692,GO:0042802,GO:0042805,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043462,GO:0043933,GO:0044057,GO:0044085,GO:0044093,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045214,GO:0048468,GO:0048513,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0051015,GO:0051049,GO:0051146,GO:0051239,GO:0051270,GO:0051336,GO:0051345,GO:0051371,GO:0051393,GO:0055001,GO:0055002,GO:0055008,GO:0055010,GO:0060047,GO:0060048,GO:0060341,GO:0060415,GO:0060537,GO:0060589,GO:0060590,GO:0061061,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070925,GO:0071688,GO:0071840,GO:0072359,GO:0090257,GO:0097435,GO:0097493,GO:0097512,GO:0098772,GO:0099080,GO:0099081,GO:0099512,GO:1903115,GO:1903522	-	ko:K12558,ko:K12568	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko04812	-	-	-	I-set,fn3
ZZS2_k127_3521946_5	316274.Haur_0935	4.108e-66	251.0	COG3055@1|root,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi	200795|Chloroflexi	KT	Kelch repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3521946_4	497964.CfE428DRAFT_1067	1.556e-116	400.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_C14,WD40
ZZS2_k127_3521946_1	1403819.BATR01000039_gene1151	7.235e-189	595.0	COG4102@1|root,COG4102@2|Bacteria,46U3G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_3527542_46	1156937.MFUM_700051	1.112e-30	133.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,37G1G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
ZZS2_k127_3527542_61	203119.Cthe_0957	6.333e-10	65.0	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
ZZS2_k127_3527542_10	497964.CfE428DRAFT_0116	5.111e-134	436.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
ZZS2_k127_3527542_6	1379698.RBG1_1C00001G1779	1.625e-147	473.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_3527542_13	880073.Calab_2467	1.295e-93	317.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_3527542_54	1403819.BATR01000086_gene2515	4.922e-19	94.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3527542_11	497964.CfE428DRAFT_3459	3.849e-105	351.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
ZZS2_k127_3527542_16	1167006.UWK_00742	4.791e-88	313.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
ZZS2_k127_3527542_40	278957.ABEA03000041_gene2213	3.707e-37	149.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
ZZS2_k127_3527542_38	497964.CfE428DRAFT_1541	2.16e-44	166.0	COG0629@1|root,COG0629@2|Bacteria,46VGA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
ZZS2_k127_3527542_64	929506.CbC4_0016	8.087e-05	49.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
ZZS2_k127_3527542_33	321332.CYB_0725	1.613e-50	186.0	COG0193@1|root,COG0193@2|Bacteria,1G0D0@1117|Cyanobacteria,1GZ78@1129|Synechococcus	1117|Cyanobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
ZZS2_k127_3527542_32	497964.CfE428DRAFT_1544	6.162e-52	192.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
ZZS2_k127_3527542_23	1156937.MFUM_870060	8.023e-66	229.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,37GGN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
ZZS2_k127_3527542_26	452637.Oter_2337	2.647e-61	214.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,3K7RG@414999|Opitutae	414999|Opitutae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
ZZS2_k127_3527542_4	497964.CfE428DRAFT_5395	2.755e-161	513.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS2_k127_3527542_58	497964.CfE428DRAFT_6519	1.203e-13	76.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_3527542_44	478741.JAFS01000001_gene1095	1.271e-33	138.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,37GG9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS2_k127_3527542_63	452637.Oter_3754	4.072e-09	68.0	2CGCF@1|root,33ZA6@2|Bacteria,46YV0@74201|Verrucomicrobia,3K85C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3527542_56	266117.Rxyl_0491	3.417e-16	89.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4CQ1P@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS2_k127_3527542_0	240016.ABIZ01000001_gene1298	1.513e-220	691.0	COG0477@1|root,COG2814@2|Bacteria,46UBZ@74201|Verrucomicrobia,2IV6W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
ZZS2_k127_3527542_43	1396141.BATP01000018_gene1518	1.088e-33	135.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
ZZS2_k127_3527542_7	452637.Oter_0201	1.06e-141	457.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,3K7N7@414999|Opitutae	414999|Opitutae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
ZZS2_k127_3527542_19	497964.CfE428DRAFT_0510	2.474e-74	254.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
ZZS2_k127_3527542_30	497964.CfE428DRAFT_0509	7.32e-54	196.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
ZZS2_k127_3527542_36	497964.CfE428DRAFT_0508	3.251e-46	171.0	COG0099@1|root,COG0099@2|Bacteria,46STA@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
ZZS2_k127_3527542_59	105559.Nwat_2137	8.46e-13	68.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,1WZNA@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
ZZS2_k127_3527542_60	575540.Isop_1048	1.811e-11	66.0	COG0361@1|root,COG0361@2|Bacteria,2J0T1@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS2_k127_3527542_18	1121430.JMLG01000033_gene1352	3.299e-82	280.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,260SK@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
ZZS2_k127_3527542_5	452637.Oter_0207	4.009e-148	482.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
ZZS2_k127_3527542_34	497964.CfE428DRAFT_0504	7.157e-49	178.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
ZZS2_k127_3527542_27	497964.CfE428DRAFT_0503	6.682e-59	212.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
ZZS2_k127_3527542_50	1121346.KB899829_gene585	2.02e-28	118.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,26XMJ@186822|Paenibacillaceae	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
ZZS2_k127_3527542_25	497964.CfE428DRAFT_0501	7.697e-63	221.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
ZZS2_k127_3527542_39	1203622.HMPREF1290_01004	9.233e-43	160.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,22MWH@1653|Corynebacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
ZZS2_k127_3527542_47	1403819.BATR01000162_gene5349	2.52e-30	121.0	COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
ZZS2_k127_3527542_24	1392493.JIAB01000001_gene2415	1.631e-63	222.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,27IA8@186928|unclassified Lachnospiraceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
ZZS2_k127_3527542_51	382464.ABSI01000011_gene2659	2.431e-27	113.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
ZZS2_k127_3527542_31	497964.CfE428DRAFT_0497	4.319e-53	189.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
ZZS2_k127_3527542_52	1403819.BATR01000164_gene5565	2.842e-27	113.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
ZZS2_k127_3527542_62	497964.CfE428DRAFT_0495	1.543e-09	61.0	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal L29 protein	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
ZZS2_k127_3527542_29	1303518.CCALI_02869	9.95e-55	194.0	COG0197@1|root,COG0197@2|Bacteria	2|Bacteria	J	tRNA binding	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
ZZS2_k127_3527542_15	452637.Oter_0220	9.581e-89	297.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
ZZS2_k127_3527542_41	497964.CfE428DRAFT_0492	9.967e-35	136.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia	74201|Verrucomicrobia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
ZZS2_k127_3527542_42	1403819.BATR01000164_gene5571	2.402e-34	133.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,2IUPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
ZZS2_k127_3527542_12	497964.CfE428DRAFT_0489	8.568e-102	339.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
ZZS2_k127_3527542_3	1122165.AUHS01000047_gene3184	3.61e-166	552.0	COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
ZZS2_k127_3527542_37	452637.Oter_3648	5.027e-45	176.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
ZZS2_k127_3527542_55	383372.Rcas_0864	1.69e-16	94.0	COG0318@1|root,COG0318@2|Bacteria,2GBKJ@200795|Chloroflexi,3781K@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3527542_14	575540.Isop_1673	4.423e-92	313.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_3527542_21	497964.CfE428DRAFT_3476	5.466e-68	248.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
ZZS2_k127_3527542_45	794903.OPIT5_03030	3.274e-33	137.0	COG1596@1|root,COG1596@2|Bacteria,46YX8@74201|Verrucomicrobia,3K89Y@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS2_k127_3527542_17	1047013.AQSP01000122_gene2225	4.981e-83	293.0	COG0642@1|root,COG4585@1|root,COG2205@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,GAF_2,HAMP,HATPase_c,HisKA_3,PAS,PAS_9,Response_reg
ZZS2_k127_3527542_22	1123487.KB892856_gene2554	5.92e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ9H@28216|Betaproteobacteria,2KW43@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_3527542_1	269799.Gmet_1669	4.468e-203	654.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
ZZS2_k127_3527542_57	518766.Rmar_2315	9.493e-14	80.0	2E3CB@1|root,32YBM@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
ZZS2_k127_3527542_2	886293.Sinac_7544	1.497e-180	603.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2J4YH@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
ZZS2_k127_3527542_20	1210884.HG799465_gene11482	5.459e-74	254.0	COG0745@1|root,COG0745@2|Bacteria,2J0GS@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Response_reg
ZZS2_k127_3527542_49	1047013.AQSP01000122_gene2227	1.16e-29	122.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	GerE,Response_reg,TauD
ZZS2_k127_3527542_8	595460.RRSWK_03471	1.153e-135	444.0	COG1657@1|root,COG1657@2|Bacteria,2J1Q5@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3527542_28	756272.Plabr_3534	7.795e-59	223.0	COG1566@1|root,COG1566@2|Bacteria,2J3HT@203682|Planctomycetes	203682|Planctomycetes	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
ZZS2_k127_3527542_9	240016.ABIZ01000001_gene1539	6.195e-135	448.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_3527542_35	908937.Prede_1989	1.592e-46	183.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
ZZS2_k127_3527542_48	1123508.JH636441_gene3117	6.271e-30	128.0	COG1413@1|root,COG1413@2|Bacteria,2J2VX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_3529768_1	1123242.JH636435_gene917	1.838e-202	637.0	COG4102@1|root,COG4102@2|Bacteria,2IY0N@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_3529768_0	886293.Sinac_1496	1.565e-304	960.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,2IYSS@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_3529768_3	1121920.AUAU01000013_gene1734	2.49e-76	265.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	MTS
ZZS2_k127_3529768_2	497964.CfE428DRAFT_1241	1.889e-169	548.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	GH3
ZZS2_k127_3529768_4	497964.CfE428DRAFT_1240	2.011e-73	256.0	2DBEV@1|root,2Z8UT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3529768_5	497964.CfE428DRAFT_1239	7.866e-15	78.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3536961_9	313612.L8106_02057	1.707e-51	188.0	COG0398@1|root,COG0398@2|Bacteria,1G3PG@1117|Cyanobacteria,1H98G@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS2_k127_3536961_15	1089547.KB913013_gene3722	1.599e-21	100.0	COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,47NQA@768503|Cytophagia	976|Bacteroidetes	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
ZZS2_k127_3536961_16	452637.Oter_0284	2.343e-18	94.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
ZZS2_k127_3536961_11	452637.Oter_0284	3.994e-35	147.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
ZZS2_k127_3536961_1	1403819.BATR01000052_gene1573	1.704e-176	561.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_3536961_14	404589.Anae109_0490	1.496e-22	98.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,42Z8C@68525|delta/epsilon subdivisions,2WU08@28221|Deltaproteobacteria,2YXJP@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3536961_12	1267535.KB906767_gene4305	1.549e-23	100.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
ZZS2_k127_3536961_4	1227739.Hsw_0070	8.174e-91	308.0	COG1409@1|root,COG3419@1|root,COG1409@2|Bacteria,COG3419@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_3536961_2	497964.CfE428DRAFT_4013	9.104e-169	540.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
ZZS2_k127_3536961_10	497964.CfE428DRAFT_5423	4.726e-37	147.0	2EPF9@1|root,33H1X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3536961_6	497964.CfE428DRAFT_1198	4.661e-78	268.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
ZZS2_k127_3536961_17	313628.LNTAR_06464	1.826e-11	73.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2
ZZS2_k127_3536961_3	335543.Sfum_1617	7.272e-93	328.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_3536961_18	1121033.AUCF01000001_gene1961	3.379e-10	72.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
ZZS2_k127_3536961_5	1156935.QWE_19483	1.35e-84	295.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS2_k127_3536961_7	1396141.BATP01000057_gene3080	3.633e-69	247.0	COG4974@1|root,COG4974@2|Bacteria,46SQ4@74201|Verrucomicrobia,2ITUM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS2_k127_3536961_0	640081.Dsui_0821	0.0	1159.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
ZZS2_k127_3536961_13	1125863.JAFN01000001_gene1573	1.879e-23	108.0	COG4676@1|root,COG5184@1|root,COG5434@1|root,COG4676@2|Bacteria,COG5184@2|Bacteria,COG5434@2|Bacteria,1R4D7@1224|Proteobacteria,42V2M@68525|delta/epsilon subdivisions,2WRUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_3540737_28	313589.JNB_04640	4.949e-20	104.0	2AJP3@1|root,31AAI@2|Bacteria,2GPNW@201174|Actinobacteria,4FIWB@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3540737_23	247490.KSU1_A0047	4.56e-33	143.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
ZZS2_k127_3540737_15	489825.LYNGBM3L_26860	8.055e-71	245.0	COG3555@1|root,COG3555@2|Bacteria,1G0W9@1117|Cyanobacteria,1H7WP@1150|Oscillatoriales	1117|Cyanobacteria	O	Aspartyl asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
ZZS2_k127_3540737_6	1123242.JH636434_gene4023	6.643e-126	421.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
ZZS2_k127_3540737_8	1123242.JH636435_gene2133	2.412e-116	384.0	COG2055@1|root,COG2055@2|Bacteria,2IZK5@203682|Planctomycetes	203682|Planctomycetes	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
ZZS2_k127_3540737_4	344747.PM8797T_27347	1.328e-152	495.0	COG3391@1|root,COG3391@2|Bacteria,2J2MH@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3540737_5	1282876.BAOK01000001_gene1772	1.126e-143	468.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TU6U@28211|Alphaproteobacteria,4BP7W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
ZZS2_k127_3540737_9	1267535.KB906767_gene4517	4.057e-104	350.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	gbd	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
ZZS2_k127_3540737_11	452637.Oter_1505	4.562e-95	317.0	COG0861@1|root,COG0861@2|Bacteria,46SNC@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
ZZS2_k127_3540737_13	1519464.HY22_08455	3.809e-73	252.0	COG0225@1|root,COG0225@2|Bacteria,1FE4X@1090|Chlorobi	1090|Chlorobi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
ZZS2_k127_3540737_25	478741.JAFS01000002_gene658	1.763e-31	127.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia,37GVS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
ZZS2_k127_3540737_16	497964.CfE428DRAFT_0064	2.103e-55	201.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_3540737_12	497964.CfE428DRAFT_0066	2.13e-77	284.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_3540737_31	1304872.JAGC01000009_gene188	4.356e-19	102.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_3540737_22	1396141.BATP01000034_gene4198	3.142e-36	160.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_3540737_1	1396141.BATP01000060_gene4727	3.924e-234	769.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_3540737_3	1123242.JH636434_gene3280	3.017e-153	496.0	COG0823@1|root,COG0823@2|Bacteria,2IYQ1@203682|Planctomycetes	203682|Planctomycetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
ZZS2_k127_3540737_2	1125863.JAFN01000001_gene1110	1.705e-177	570.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria	1224|Proteobacteria	G	phosphomannomutase	noeK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS2_k127_3540737_29	1123277.KB893232_gene1924	1.019e-19	107.0	COG3630@1|root,COG3630@2|Bacteria,4PKCP@976|Bacteroidetes,47Y7J@768503|Cytophagia	976|Bacteroidetes	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
ZZS2_k127_3540737_0	1396141.BATP01000043_gene1929	4.806e-278	938.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_3540737_33	926562.Oweho_0246	4.523e-15	92.0	COG3211@1|root,COG3211@2|Bacteria,4NZ53@976|Bacteroidetes,1IN2H@117743|Flavobacteriia,2PC64@246874|Cryomorphaceae	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_3540737_40	377629.TERTU_1111	0.0009423	54.0	COG1664@1|root,COG3210@1|root,COG1664@2|Bacteria,COG3210@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,2PPFJ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	MU	Concanavalin A-like lectin/glucanases superfamily	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,Laminin_G_3,PA14
ZZS2_k127_3540737_26	1396141.BATP01000042_gene1928	4.361e-30	141.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_3540737_37	438753.AZC_2787	1.172e-08	63.0	COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,2U0TX@28211|Alphaproteobacteria,3F1NS@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	PFAM MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
ZZS2_k127_3540737_7	497964.CfE428DRAFT_2622	6.949e-123	403.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
ZZS2_k127_3540737_14	1291743.LOSG293_060300	6.418e-72	253.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS2_k127_3540737_18	497964.CfE428DRAFT_0286	1.795e-47	171.0	2DR28@1|root,339V9@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
ZZS2_k127_3540737_38	1051632.TPY_1782	2.763e-06	59.0	COG2404@1|root,COG2404@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	nrnB	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
ZZS2_k127_3540737_10	240016.ABIZ01000001_gene913	3.645e-96	321.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,2ITNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
ZZS2_k127_3540737_19	546271.Selsp_0582	1.572e-44	173.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4H2FC@909932|Negativicutes	909932|Negativicutes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
ZZS2_k127_3540737_27	187272.Mlg_0939	1.106e-25	112.0	COG0735@1|root,COG0735@2|Bacteria,1NEZS@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ZZS2_k127_3540737_21	880072.Desac_0144	5.367e-43	168.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WPQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
ZZS2_k127_3540737_17	717785.HYPMC_4091	5.241e-53	197.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,3N6PS@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
ZZS2_k127_3540737_20	102125.Xen7305DRAFT_00006140	3.709e-43	170.0	COG0803@1|root,COG0803@2|Bacteria,1G04M@1117|Cyanobacteria,3VIGR@52604|Pleurocapsales	1117|Cyanobacteria	P	ABC-type metal ion transport system periplasmic component surface adhesin	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
ZZS2_k127_3540737_35	497964.CfE428DRAFT_2341	7.41e-12	74.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S18	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
ZZS2_k127_3540737_30	1353529.M899_0700	2.298e-19	88.0	COG0267@1|root,COG0267@2|Bacteria,1Q1V0@1224|Proteobacteria,437HE@68525|delta/epsilon subdivisions,2MTDQ@213481|Bdellovibrionales,2X2QY@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
ZZS2_k127_3540737_24	497964.CfE428DRAFT_2343	6.556e-33	136.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
ZZS2_k127_3566225_1	247490.KSU1_B0582	0.0	1017.0	COG3227@1|root,COG4935@1|root,COG3227@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.24.28	ko:K01400,ko:K01417,ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CARDB,CarboxypepD_reg,DUF11,F5_F8_type_C,FTP,P_proprotein,Peptidase_M36,Peptidase_S8
ZZS2_k127_3566225_9	1121403.AUCV01000028_gene2416	1.807e-11	69.0	2DT2U@1|root,33IFQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3566225_2	373994.Riv7116_5177	2.147e-229	736.0	COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,1HMQN@1161|Nostocales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
ZZS2_k127_3566225_5	32057.KB217483_gene9341	3.264e-114	384.0	28PII@1|root,2ZC8H@2|Bacteria,1G86U@1117|Cyanobacteria,1HU8G@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
ZZS2_k127_3566225_7	99598.Cal7507_3723	9.541e-81	275.0	2AAD4@1|root,30ZP1@2|Bacteria,1GAXN@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM T4 bacteriophage base plate protein	-	-	-	-	-	-	-	-	-	-	-	-	T4_baseplate
ZZS2_k127_3566225_6	114615.BRADO4389	4.042e-93	307.0	2DB76@1|root,2Z7JZ@2|Bacteria,1R41X@1224|Proteobacteria,2U1DC@28211|Alphaproteobacteria,3K33V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
ZZS2_k127_3566225_3	114615.BRADO4390	2.127e-216	687.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2TVB3@28211|Alphaproteobacteria,3K07D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
ZZS2_k127_3566225_4	909663.KI867151_gene3093	1.001e-120	404.0	COG2204@1|root,COG2204@2|Bacteria,1NH9G@1224|Proteobacteria,42ZAJ@68525|delta/epsilon subdivisions,2WU3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
ZZS2_k127_3566225_12	1123248.KB893381_gene1089	0.0008324	47.0	COG1345@1|root,COG2931@1|root,COG3055@1|root,COG3386@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,4NK33@976|Bacteroidetes,1IX26@117747|Sphingobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3566225_0	794903.OPIT5_27280	0.0	1353.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,3K96P@414999|Opitutae	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
ZZS2_k127_3569030_0	497964.CfE428DRAFT_2616	1.758e-218	688.0	28MB8@1|root,2ZAPS@2|Bacteria,46U9F@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3569030_1	382464.ABSI01000005_gene1011	1.084e-141	462.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,2IVDM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
ZZS2_k127_3610343_0	497964.CfE428DRAFT_6175	2.605e-226	744.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46UEG@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
ZZS2_k127_3610343_8	1237149.C900_02976	3.39e-17	97.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3610343_3	1279009.ADICEAN_03353	2.053e-115	404.0	COG4547@1|root,COG4932@1|root,COG5644@1|root,COG4547@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
ZZS2_k127_3610343_1	1303518.CCALI_01058	2.221e-160	513.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	nirH	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
ZZS2_k127_3610343_7	1254432.SCE1572_33240	6.175e-28	123.0	COG1073@1|root,COG1073@2|Bacteria,1QYFN@1224|Proteobacteria,434P1@68525|delta/epsilon subdivisions,2WZ0B@28221|Deltaproteobacteria,2Z120@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3610343_4	1396141.BATP01000028_gene2349	1.574e-107	357.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,2ITHA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
ZZS2_k127_3610343_2	497964.CfE428DRAFT_5019	1.327e-124	408.0	COG0077@1|root,COG0077@2|Bacteria,46U8V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
ZZS2_k127_3610343_6	1396418.BATQ01000141_gene3395	9.632e-42	163.0	COG1386@1|root,COG1386@2|Bacteria,46VRU@74201|Verrucomicrobia,2IUTS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Segregation and condensation complex subunit ScpB	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpB
ZZS2_k127_3610343_5	497964.CfE428DRAFT_5017	7.247e-73	260.0	COG1354@1|root,COG1354@2|Bacteria,46UBD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpA
ZZS2_k127_3610343_9	497964.CfE428DRAFT_0147	9.257e-15	81.0	29XKD@1|root,30JBH@2|Bacteria,46W5S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
ZZS2_k127_3611473_2	1156937.MFUM_230013	4.134e-136	449.0	COG0642@1|root,COG2205@2|Bacteria,46UHY@74201|Verrucomicrobia,37GB8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
ZZS2_k127_3611473_3	269799.Gmet_2437	2.666e-84	286.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_3611473_5	313606.M23134_03514	1.369e-40	162.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
ZZS2_k127_3611473_6	1227739.Hsw_PA0019	5.672e-27	117.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
ZZS2_k127_3611473_1	1279009.ADICEAN_00454	1.163e-151	494.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
ZZS2_k127_3611473_4	1453500.AT05_05490	3.902e-47	176.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
ZZS2_k127_3611473_0	1358423.N180_10530	0.0	1068.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
ZZS2_k127_3611473_7	1191523.MROS_1512	8.886e-08	58.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
ZZS2_k127_3620665_2	234267.Acid_5276	3.46e-22	95.0	COG2764@1|root,COG2764@2|Bacteria,3Y4Z2@57723|Acidobacteria	57723|Acidobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_3620665_3	533240.CRC_01020	1.717e-14	89.0	COG1404@1|root,COG2931@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3121@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_3620665_1	1121920.AUAU01000009_gene1881	3.635e-61	243.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_3620665_0	498848.TaqDRAFT_4878	7.725e-73	281.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_362913_8	1184267.A11Q_2226	1.525e-08	57.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,42SJ2@68525|delta/epsilon subdivisions,2MTY7@213481|Bdellovibrionales,2WPC9@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	regulator	-	-	-	ko:K07773	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
ZZS2_k127_362913_2	1173024.KI912151_gene1713	7.571e-38	149.0	COG2204@1|root,COG4251@1|root,COG2204@2|Bacteria,COG4251@2|Bacteria,1G3QY@1117|Cyanobacteria,1JJHZ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
ZZS2_k127_362913_9	1396141.BATP01000062_gene4458	2.065e-07	66.0	COG1082@1|root,COG2730@1|root,COG3119@1|root,COG3250@1|root,COG3533@1|root,COG4733@1|root,COG5297@1|root,COG1082@2|Bacteria,COG2730@2|Bacteria,COG3119@2|Bacteria,COG3250@2|Bacteria,COG3533@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	AP_endonuc_2,Alginate_lyase,Laminin_G_3,NPCBM
ZZS2_k127_362913_4	1121920.AUAU01000009_gene1881	2.863e-23	119.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_362913_0	1396141.BATP01000003_gene4934	7.876e-166	584.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_362913_3	755732.Fluta_1212	1.48e-35	159.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_362913_6	1396141.BATP01000034_gene4198	3.073e-18	101.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_362913_5	864051.BurJ1DRAFT_0895	9.393e-21	109.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
ZZS2_k127_362913_1	583355.Caka_1736	2.884e-99	362.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_362913_7	945713.IALB_2577	5.557e-10	74.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
ZZS2_k127_3633116_6	1123248.KB893381_gene1089	1.043e-09	67.0	COG1345@1|root,COG2931@1|root,COG3055@1|root,COG3386@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,4NK33@976|Bacteroidetes,1IX26@117747|Sphingobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3633116_2	317936.Nos7107_4210	3.392e-140	463.0	COG1075@1|root,COG1075@2|Bacteria,1GIQY@1117|Cyanobacteria,1HP99@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3633116_0	1192759.AKIB01000028_gene2028	6.189e-216	759.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3386@1|root,COG3391@1|root,COG5276@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2UHRC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FGMQ	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,He_PIG,Laminin_G_3
ZZS2_k127_3633116_3	10224.XP_006822956.1	1.647e-99	373.0	KOG1225@1|root,KOG3594@1|root,KOG3714@1|root,KOG1219@2759|Eukaryota,KOG1225@2759|Eukaryota,KOG3594@2759|Eukaryota,KOG3714@2759|Eukaryota,KOG4289@2759|Eukaryota,38YEN@33154|Opisthokonta,3CNSM@33208|Metazoa,3E4Z0@33213|Bilateria	33208|Metazoa	T	Coagulation factor 5/8 C-terminal domain, discoidin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,F5_F8_type_C,TIG
ZZS2_k127_3633116_4	452637.Oter_1864	1.233e-50	189.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
ZZS2_k127_3633116_1	1403819.BATR01000096_gene3165	2.794e-156	507.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3356@1|root,COG4625@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3356@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_C,HEAT_2,Laminin_G_3,ThuA
ZZS2_k127_3651802_1	497964.CfE428DRAFT_4864	7.161e-60	224.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3651802_3	1123276.KB893290_gene5291	0.0008473	53.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
ZZS2_k127_3651802_0	768706.Desor_4071	1.409e-70	251.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,260EI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_3651802_2	1132509.C447_07293	8.814e-06	58.0	COG3794@1|root,arCOG02921@2157|Archaea,2XX78@28890|Euryarchaeota,241G7@183963|Halobacteria	28890|Euryarchaeota	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
ZZS2_k127_3673377_5	1396141.BATP01000043_gene1929	4.638e-68	265.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_3673377_6	1396418.BATQ01000091_gene5770	8.72e-26	126.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3204@1|root,COG3291@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
ZZS2_k127_3673377_2	448385.sce3153	4.161e-87	295.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
ZZS2_k127_3673377_9	1040989.AWZU01000063_gene6224	0.0004151	53.0	COG2202@1|root,COG3210@1|root,COG2202@2|Bacteria,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,2TWQT@28211|Alphaproteobacteria,3K6MB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Hyphal_reg_CWP
ZZS2_k127_3673377_1	1211777.BN77_p11114	1.444e-129	441.0	COG2202@1|root,COG2984@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
ZZS2_k127_3673377_0	497964.CfE428DRAFT_1144	6.712e-239	780.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,46TZW@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Reg_prop,Y_Y_Y
ZZS2_k127_3673377_4	1211777.BN77_p11113	1.638e-76	262.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2U895@28211|Alphaproteobacteria,4BAEM@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_3673377_3	1454004.AW11_00930	1.505e-85	290.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,2WC2P@28216|Betaproteobacteria,1KR2C@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3673377_10	326297.Sama_3406	0.0004918	50.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,2Q9HF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
ZZS2_k127_3673377_8	1232410.KI421421_gene3334	3.524e-12	75.0	2DT2H@1|root,33IDP@2|Bacteria,1NXAG@1224|Proteobacteria,430YG@68525|delta/epsilon subdivisions,2WVZY@28221|Deltaproteobacteria,43VAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
ZZS2_k127_3674900_2	497964.CfE428DRAFT_4660	3.402e-167	537.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_3674900_6	1123242.JH636434_gene3333	5.71e-100	350.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
ZZS2_k127_3674900_5	1123242.JH636435_gene1336	1.885e-103	361.0	COG0673@1|root,COG2319@1|root,COG0673@2|Bacteria,COG2319@2|Bacteria,2IWZY@203682|Planctomycetes	203682|Planctomycetes	G	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_3674900_10	278957.ABEA03000008_gene3231	4.637e-65	227.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia,3K7PZ@414999|Opitutae	414999|Opitutae	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
ZZS2_k127_3674900_12	760568.Desku_1853	5.776e-61	218.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
ZZS2_k127_3674900_14	686340.Metal_2132	3.221e-27	131.0	COG2373@1|root,COG3209@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,1QV7E@1224|Proteobacteria,1T3HZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	TIGRFAM Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3674900_15	755178.Cyan10605_0212	4.362e-19	104.0	COG4409@1|root,COG4409@2|Bacteria,1GG92@1117|Cyanobacteria	1117|Cyanobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3674900_19	1122182.KB903838_gene4056	4.293e-08	68.0	COG2133@1|root,COG2133@2|Bacteria,2HEMB@201174|Actinobacteria,4DA70@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PA14,PKD
ZZS2_k127_3674900_11	1396141.BATP01000042_gene1927	2.963e-62	246.0	COG1520@1|root,COG4625@1|root,COG5295@1|root,COG1520@2|Bacteria,COG4625@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
ZZS2_k127_3674900_13	1147.D082_25660	2.495e-30	141.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
ZZS2_k127_3674900_8	883.DvMF_1031	7.653e-75	269.0	COG2805@1|root,COG2805@2|Bacteria,1NEYE@1224|Proteobacteria,43B76@68525|delta/epsilon subdivisions,2X6KM@28221|Deltaproteobacteria,2MH47@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
ZZS2_k127_3674900_9	330214.NIDE0051	1.227e-67	236.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS2_k127_3674900_1	1396141.BATP01000057_gene2986	7.533e-172	553.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,2ITRR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
ZZS2_k127_3674900_0	1396141.BATP01000024_gene849	0.0	1450.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
ZZS2_k127_3674900_3	1396141.BATP01000024_gene848	4.818e-140	465.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
ZZS2_k127_3674900_17	794903.OPIT5_16420	4.081e-16	91.0	COG1538@1|root,COG1538@2|Bacteria,46VWC@74201|Verrucomicrobia,3K8JX@414999|Opitutae	414999|Opitutae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_3674900_18	1396418.BATQ01000175_gene2816	2.988e-15	78.0	2EM29@1|root,33ERR@2|Bacteria,46WJK@74201|Verrucomicrobia,2IWEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3674900_4	390235.PputW619_4197	1.277e-105	359.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1YWIY@136845|Pseudomonas putida group	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
ZZS2_k127_3674900_7	264732.Moth_1083	1.818e-93	314.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
ZZS2_k127_3674900_16	1453505.JASY01000001_gene3406	3.686e-18	87.0	COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,1I57R@117743|Flavobacteriia,2NXG5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
ZZS2_k127_3687002_1	497964.CfE428DRAFT_0776	2.422e-296	929.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
ZZS2_k127_3687002_3	204669.Acid345_1383	3.427e-120	396.0	2CEY7@1|root,2Z8CG@2|Bacteria,3Y70V@57723|Acidobacteria,2JKPR@204432|Acidobacteriia	204432|Acidobacteriia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3687002_0	204669.Acid345_1384	2.218e-298	924.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS2_k127_3687002_2	1210884.HG799466_gene12573	6.678e-132	425.0	COG0479@1|root,COG0479@2|Bacteria,2J136@203682|Planctomycetes	203682|Planctomycetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
ZZS2_k127_3687002_5	1210884.HG799466_gene12574	3.593e-46	172.0	2EDAV@1|root,33776@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3687002_4	1396141.BATP01000060_gene4628	1.687e-46	177.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_3687002_7	240016.ABIZ01000001_gene1762	1.351e-05	55.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	tnp15	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
ZZS2_k127_3687002_6	1297742.A176_07208	2.066e-10	65.0	COG1940@1|root,COG1940@2|Bacteria,1QARE@1224|Proteobacteria,43596@68525|delta/epsilon subdivisions,2X971@28221|Deltaproteobacteria,2Z2B2@29|Myxococcales	28221|Deltaproteobacteria	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3687090_6	1403819.BATR01000133_gene4702	9.834e-81	279.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	exsA	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141	-	ko:K20968	ko02025,map02025	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_18
ZZS2_k127_3687090_12	497964.CfE428DRAFT_0981	3.851e-18	101.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
ZZS2_k127_3687090_0	886293.Sinac_3115	0.0	1046.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IXK7@203682|Planctomycetes	203682|Planctomycetes	C	TIGRFAM membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_3687090_11	317619.ANKN01000161_gene300	3.813e-18	97.0	COG0388@1|root,COG0388@2|Bacteria,1G103@1117|Cyanobacteria,1MKIZ@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
ZZS2_k127_3687090_17	483219.LILAB_15610	3.942e-06	59.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
ZZS2_k127_3687090_15	113355.CM001775_gene2954	2.119e-09	70.0	COG0515@1|root,COG0515@2|Bacteria	113355.CM001775_gene2954|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3687090_14	537013.CLOSTMETH_01946	3.393e-10	66.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3WJ4F@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain protein	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_3687090_16	243090.RB10734	2.494e-06	52.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	mucD	-	3.4.21.107	ko:K04771,ko:K07126	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	TerD,Trypsin_2
ZZS2_k127_3687090_2	530564.Psta_2150	1.336e-112	377.0	COG1520@1|root,COG1520@2|Bacteria,2IYV0@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_3687090_4	240016.ABIZ01000001_gene2422	5.976e-94	319.0	COG1943@1|root,COG1943@2|Bacteria,46V7I@74201|Verrucomicrobia,2IVMQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
ZZS2_k127_3687090_13	1122925.KB895378_gene2567	9.609e-16	92.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_3687090_1	234267.Acid_7008	1.034e-149	486.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_3687090_5	1123070.KB899258_gene1884	9.933e-85	297.0	2CCWM@1|root,338WR@2|Bacteria,46ZKG@74201|Verrucomicrobia,2IVHM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3687090_3	240016.ABIZ01000001_gene5357	7.342e-109	366.0	COG1216@1|root,COG1216@2|Bacteria,46XEI@74201|Verrucomicrobia,2IVPA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_3687090_8	1173025.GEI7407_2042	3.24e-63	232.0	COG0463@1|root,COG0463@2|Bacteria,1G4DE@1117|Cyanobacteria,1H9EJ@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_3687090_10	945713.IALB_2887	3.47e-19	95.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
ZZS2_k127_3687090_7	1242864.D187_000451	7.083e-78	278.0	COG3307@1|root,COG3307@2|Bacteria,1NDGK@1224|Proteobacteria	1224|Proteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_3687090_9	240016.ABIZ01000001_gene5359	1.173e-58	221.0	COG0438@1|root,COG0438@2|Bacteria,46ZJA@74201|Verrucomicrobia,2IV7H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_3690414_13	383372.Rcas_1067	6.839e-79	268.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
ZZS2_k127_3690414_14	497964.CfE428DRAFT_2508	9.809e-78	264.0	COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
ZZS2_k127_3690414_23	886293.Sinac_5202	5.674e-40	160.0	COG3386@1|root,COG3386@2|Bacteria,2J4VK@203682|Planctomycetes	203682|Planctomycetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3690414_4	1128421.JAGA01000002_gene1363	3.183e-157	523.0	COG2217@1|root,COG2217@2|Bacteria,2NNPJ@2323|unclassified Bacteria	2|Bacteria	P	E1-E2 ATPase	copA	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944	3.6.3.54	ko:K12949,ko:K12956,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
ZZS2_k127_3690414_3	1122194.AUHU01000007_gene278	3.531e-185	595.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0405 Gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS2_k127_3690414_17	497964.CfE428DRAFT_3693	1.685e-58	221.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
ZZS2_k127_3690414_15	880073.Calab_1235	3.516e-61	220.0	COG0035@1|root,COG0035@2|Bacteria,2NP5M@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
ZZS2_k127_3690414_10	497964.CfE428DRAFT_2401	8.382e-107	359.0	COG0006@1|root,COG0006@2|Bacteria,46SKG@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
ZZS2_k127_3690414_25	1396418.BATQ01000008_gene1536	9.626e-34	135.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
ZZS2_k127_3690414_0	1116472.MGMO_111c00270	1.791e-270	843.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XESA@135618|Methylococcales	135618|Methylococcales	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ZZS2_k127_3690414_9	247490.KSU1_D1048	2.618e-113	376.0	COG3842@1|root,COG3842@2|Bacteria,2IZ1J@203682|Planctomycetes	203682|Planctomycetes	P	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,TOBE_2
ZZS2_k127_3690414_8	247490.KSU1_D1047	6.041e-120	400.0	COG1840@1|root,COG1840@2|Bacteria,2J39X@203682|Planctomycetes	203682|Planctomycetes	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
ZZS2_k127_3690414_18	1121920.AUAU01000004_gene839	3.735e-56	199.0	COG0590@1|root,COG0590@2|Bacteria,3Y4ZN@57723|Acidobacteria	57723|Acidobacteria	FJ	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
ZZS2_k127_3690414_7	278957.ABEA03000206_gene3779	4.119e-131	425.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
ZZS2_k127_3690414_22	1459636.NTE_02269	2.144e-47	177.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
ZZS2_k127_3690414_16	1042375.AFPL01000055_gene2315	1.387e-60	218.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,467K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
ZZS2_k127_3690414_21	85643.Tmz1t_1312	1.209e-52	204.0	COG0745@1|root,COG4585@1|root,COG0745@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,2KWH2@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4,Response_reg
ZZS2_k127_3690414_20	1047013.AQSP01000134_gene1332	7.224e-53	209.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS2_k127_3690414_5	497964.CfE428DRAFT_5023	1.774e-148	480.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_3690414_11	497964.CfE428DRAFT_5022	1.305e-99	337.0	COG1136@1|root,COG1136@2|Bacteria,46SKR@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_3690414_12	452637.Oter_3643	4.302e-90	319.0	COG0845@1|root,COG0845@2|Bacteria,46TJP@74201|Verrucomicrobia,3K7D1@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
ZZS2_k127_3690414_2	562970.Btus_2805	5.486e-194	626.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,2783I@186823|Alicyclobacillaceae	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
ZZS2_k127_3690414_1	583355.Caka_3109	2.276e-207	709.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
ZZS2_k127_3690414_29	641526.ADIWIN_3822	3.997e-08	67.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Laminin_G_3
ZZS2_k127_3690414_27	682795.AciX8_3725	3.153e-17	97.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
ZZS2_k127_3690414_28	146922.JOFU01000012_gene1787	1.007e-08	69.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
ZZS2_k127_3690414_30	638303.Thal_0535	1.888e-05	50.0	COG0268@1|root,COG0268@2|Bacteria,2G49M@200783|Aquificae	200783|Aquificae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
ZZS2_k127_3690414_19	640511.BC1002_1278	1.544e-55	210.0	COG1262@1|root,COG2319@1|root,COG1262@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
ZZS2_k127_3690414_24	521098.Aaci_1325	6.722e-39	157.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ZZS2_k127_3690414_6	395961.Cyan7425_1966	7.627e-144	472.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS2_k127_3690414_26	1396141.BATP01000051_gene3337	4.766e-20	93.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	LysM,PD40
ZZS2_k127_376899_2	497964.CfE428DRAFT_5287	9.585e-18	88.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_376899_1	497964.CfE428DRAFT_5288	5.504e-56	206.0	COG0811@1|root,COG0811@2|Bacteria,46V4I@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
ZZS2_k127_376899_3	515620.EUBELI_01713	2.985e-13	81.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,25VXD@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
ZZS2_k127_376899_0	761193.Runsl_4666	3.763e-111	378.0	COG3292@1|root,COG3292@2|Bacteria,4P11P@976|Bacteroidetes,47TF0@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
ZZS2_k127_3810057_1	1123242.JH636434_gene4804	1.544e-45	176.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ZZS2_k127_3810057_5	880072.Desac_1044	1.673e-07	55.0	COG1598@1|root,COG1598@2|Bacteria,1NN6Y@1224|Proteobacteria	1224|Proteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
ZZS2_k127_3810057_0	452637.Oter_0080	2.672e-50	185.0	COG0810@1|root,COG1595@1|root,COG0810@2|Bacteria,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,3K9H7@414999|Opitutae	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_3810057_2	1463920.JOGB01000013_gene371	7.374e-45	188.0	2A7DD@1|root,30WAJ@2|Bacteria,2HAGJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3810057_3	203119.Cthe_0316	7.613e-39	169.0	COG2133@1|root,COG5183@1|root,COG2133@2|Bacteria,COG5183@2|Bacteria,1VRJN@1239|Firmicutes	1239|Firmicutes	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14,RsgI_N
ZZS2_k127_3896523_4	330214.NIDE0590	5.166e-93	315.0	COG3733@1|root,COG3733@2|Bacteria	2|Bacteria	Q	amine oxidase	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid
ZZS2_k127_3896523_17	1184267.A11Q_1310	5.178e-08	57.0	COG0500@1|root,COG2226@2|Bacteria,1R9JW@1224|Proteobacteria,42M76@68525|delta/epsilon subdivisions,2MTER@213481|Bdellovibrionales,2WK4P@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
ZZS2_k127_3896523_10	292564.Cyagr_3100	1.448e-46	184.0	2BP4Z@1|root,32HVT@2|Bacteria,1GMQJ@1117|Cyanobacteria,22TQW@167375|Cyanobium	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3896523_16	1183438.GKIL_4381	3.938e-09	64.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein,Peptidase_S8,VCBS
ZZS2_k127_3896523_9	671143.DAMO_3156	5.089e-48	192.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS2_k127_3896523_8	1266914.ATUK01000001_gene746	1.254e-66	236.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_3896523_3	1156937.MFUM_1020047	5.038e-94	323.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,37G6B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	MacB-like periplasmic core domain	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
ZZS2_k127_3896523_11	56780.SYN_00581	2.708e-28	120.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
ZZS2_k127_3896523_2	1403819.BATR01000094_gene2961	5.389e-103	347.0	COG1363@1|root,COG1363@2|Bacteria,46SM3@74201|Verrucomicrobia,2IU2V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
ZZS2_k127_3896523_14	583355.Caka_1594	1.495e-15	92.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46W2M@74201|Verrucomicrobia,3K81K@414999|Opitutae	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
ZZS2_k127_3896523_5	1123242.JH636435_gene1069	1.249e-84	299.0	COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria,2J2YH@203682|Planctomycetes	203682|Planctomycetes	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA,VipB
ZZS2_k127_3896523_7	118166.JH976537_gene3466	3.243e-67	235.0	COG1926@1|root,COG1926@2|Bacteria,1G2IS@1117|Cyanobacteria,1H9WZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
ZZS2_k127_3896523_13	983545.Glaag_3599	1.175e-24	122.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria,466C4@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_3896523_0	452637.Oter_2954	4.542e-288	923.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3896523_6	1267535.KB906767_gene3857	3.493e-83	308.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
ZZS2_k127_3896523_15	530564.Psta_2280	1.599e-11	78.0	COG2911@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_3896523_1	497964.CfE428DRAFT_0427	1.325e-203	656.0	COG0613@1|root,COG0613@2|Bacteria,46TNI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3896523_12	234267.Acid_3349	4.134e-28	123.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
ZZS2_k127_3920241_4	1492737.FEM08_24910	7.581e-68	233.0	COG1917@1|root,COG1917@2|Bacteria,4NU2G@976|Bacteroidetes	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_3920241_0	243090.RB413	2.227e-86	297.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,DUF4380
ZZS2_k127_3920241_6	1469607.KK073768_gene2086	1.993e-20	95.0	COG1397@1|root,COG1397@2|Bacteria,1G5Y5@1117|Cyanobacteria,1HR9M@1161|Nostocales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
ZZS2_k127_3920241_2	1267534.KB906754_gene2794	1.551e-80	273.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_3920241_8	111780.Sta7437_2550	0.0002573	53.0	COG0457@1|root,COG0457@2|Bacteria	111780.Sta7437_2550|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3920241_1	1403819.BATR01000122_gene4331	1.311e-81	284.0	2BWKA@1|root,32QZQ@2|Bacteria	2|Bacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_3920241_5	382464.ABSI01000010_gene3256	5.564e-28	116.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,MORN,MORN_2
ZZS2_k127_3931486_6	1089547.KB913013_gene4534	0.0002377	46.0	COG4643@1|root,COG4914@1|root,COG4643@2|Bacteria,COG4914@2|Bacteria,4NTQ4@976|Bacteroidetes,47RZ9@768503|Cytophagia	976|Bacteroidetes	P	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
ZZS2_k127_3931486_2	1210884.HG799472_gene14911	1.756e-80	283.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_3931486_1	1210884.HG799466_gene12802	3.845e-272	861.0	COG3661@1|root,COG3661@2|Bacteria	2|Bacteria	G	alpha-glucuronidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_67N
ZZS2_k127_3931486_0	1396141.BATP01000022_gene418	0.0	1013.0	COG4993@1|root,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia,2ITXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
ZZS2_k127_3931486_5	452637.Oter_1887	4.346e-05	49.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_3931486_4	452637.Oter_1875	1.617e-12	70.0	COG0577@1|root,COG0577@2|Bacteria,46TJI@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_3931486_3	279714.FuraDRAFT_1164	5.208e-70	240.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VRJ0@28216|Betaproteobacteria,2KT22@206351|Neisseriales	206351|Neisseriales	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
ZZS2_k127_3935174_3	452637.Oter_2811	2.685e-90	305.0	COG0330@1|root,COG0330@2|Bacteria,46WFJ@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_3935174_4	452637.Oter_2811	9.434e-89	301.0	COG0330@1|root,COG0330@2|Bacteria,46WFJ@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_3935174_14	861299.J421_1306	1.357e-11	69.0	COG0296@1|root,COG0296@2|Bacteria,1ZU2E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
ZZS2_k127_3935174_7	404380.Gbem_2115	1.999e-56	207.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
ZZS2_k127_3935174_9	313612.L8106_15325	1.306e-34	141.0	COG0745@1|root,COG0745@2|Bacteria,1GQUJ@1117|Cyanobacteria,1HI0J@1150|Oscillatoriales	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_3935174_8	497964.CfE428DRAFT_1861	1.954e-41	170.0	COG1595@1|root,COG4194@1|root,COG1595@2|Bacteria,COG4194@2|Bacteria,46TQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_3935174_10	980584.AFPB01000138_gene2681	2.732e-34	137.0	COG1017@1|root,COG1017@2|Bacteria,4PK8Z@976|Bacteroidetes,1IEWB@117743|Flavobacteriia,40777@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	Globin
ZZS2_k127_3935174_1	1173022.Cri9333_4223	2.921e-102	360.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
ZZS2_k127_3935174_6	1396141.BATP01000025_gene980	1.513e-73	256.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_3935174_12	886293.Sinac_3371	1.637e-17	98.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_3935174_5	234267.Acid_1210	7.037e-86	313.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amino_oxidase,Ank,Ank_2,Ank_3,Ank_4,Ank_5,PSCyt1,Peptidase_C14,Prenyltrans,SQHop_cyclase_C
ZZS2_k127_3935174_11	583355.Caka_0122	4.051e-28	133.0	COG3401@1|root,COG3506@1|root,COG4447@1|root,COG3401@2|Bacteria,COG3506@2|Bacteria,COG4447@2|Bacteria,46VQN@74201|Verrucomicrobia,3K8HG@414999|Opitutae	414999|Opitutae	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3935174_0	1396141.BATP01000022_gene449	4.61e-192	637.0	COG2133@1|root,COG3291@1|root,COG3468@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF756,PKD,TED
ZZS2_k127_3935174_15	1192034.CAP_8932	2.854e-08	62.0	COG3861@1|root,COG3861@2|Bacteria,1QE0P@1224|Proteobacteria,42TDZ@68525|delta/epsilon subdivisions,2WPW5@28221|Deltaproteobacteria,2Z2TG@29|Myxococcales	28221|Deltaproteobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3935174_13	497964.CfE428DRAFT_5365	6.159e-12	71.0	COG2172@1|root,COG2172@2|Bacteria,46TBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
ZZS2_k127_3940191_1	153721.MYP_3421	5.705e-36	155.0	COG4222@1|root,COG4222@2|Bacteria,4NJ6G@976|Bacteroidetes,47QCY@768503|Cytophagia	976|Bacteroidetes	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,Phytase-like
ZZS2_k127_3940191_0	251221.35213566	6.339e-61	225.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3984696_0	1396141.BATP01000047_gene3874	2.018e-231	732.0	COG1621@1|root,COG3468@1|root,COG1621@2|Bacteria,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	BetaGal_dom2,BetaGal_dom3,BetaGal_dom4_5,Big_2,Glyco_hydro_32N,Glyco_hydro_35,Glyco_hydro_43,PATR,SLH
ZZS2_k127_3984696_3	376686.Fjoh_3324	6.097e-06	59.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
ZZS2_k127_3984696_1	479431.Namu_4469	2.225e-67	251.0	COG5184@1|root,COG5184@2|Bacteria,2I6ND@201174|Actinobacteria,4EXGV@85013|Frankiales	201174|Actinobacteria	DZ	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3984696_2	1396141.BATP01000001_gene5308	9.812e-07	60.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_3986352_9	1056820.KB900681_gene2859	9.648e-58	205.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
ZZS2_k127_3986352_8	269796.Rru_A2053	1.102e-68	238.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2U5GN@28211|Alphaproteobacteria,2JRVE@204441|Rhodospirillales	204441|Rhodospirillales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ZZS2_k127_3986352_6	1403819.BATR01000137_gene4884	3.444e-76	265.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
ZZS2_k127_3986352_4	378806.STAUR_7504	3.932e-126	440.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
ZZS2_k127_3986352_10	497964.CfE428DRAFT_1653	2.169e-54	198.0	COG2197@1|root,COG2197@2|Bacteria,46U17@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_3986352_7	583355.Caka_1792	1.248e-70	248.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,3K75I@414999|Opitutae	414999|Opitutae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
ZZS2_k127_3986352_5	1396141.BATP01000057_gene2988	1.802e-76	268.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,2ITUW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DHHA1 domain	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS2_k127_3986352_11	760568.Desku_2542	8.215e-18	89.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,262H0@186807|Peptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
ZZS2_k127_3986352_0	481448.Minf_1864	1.508e-203	662.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,37FYY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
ZZS2_k127_3986352_2	497964.CfE428DRAFT_1789	1.389e-141	466.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
ZZS2_k127_3986352_3	585394.RHOM_12005	6.146e-134	433.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
ZZS2_k127_3986352_1	1045858.Bint_1756	4.053e-164	522.0	COG1089@1|root,COG1089@2|Bacteria,2J78G@203691|Spirochaetes	203691|Spirochaetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
ZZS2_k127_4005065_21	1396418.BATQ01000110_gene4800	0.0007619	44.0	2E4YE@1|root,32ZSA@2|Bacteria,46WYD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4005065_20	1403819.BATR01000153_gene5137	1.336e-07	58.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	XK27_09985	-	-	-	-	-	-	-	-	-	-	-	DUF1232
ZZS2_k127_4005065_3	1156937.MFUM_1020111	5.391e-111	374.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,37FVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
ZZS2_k127_4005065_2	497964.CfE428DRAFT_6050	1.808e-112	370.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
ZZS2_k127_4005065_18	1499967.BAYZ01000118_gene3298	5.921e-19	90.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
ZZS2_k127_4005065_6	1121346.KB899821_gene2706	4.308e-101	348.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,26UP7@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
ZZS2_k127_4005065_8	273068.TTE0770	1.416e-77	273.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
ZZS2_k127_4005065_16	243090.RB347	1.282e-40	159.0	COG3411@1|root,COG3411@2|Bacteria,2J0ZA@203682|Planctomycetes	203682|Planctomycetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4005065_14	1345697.M493_10975	1.027e-50	199.0	COG0318@1|root,COG0318@2|Bacteria,1UKBR@1239|Firmicutes,4ITH5@91061|Bacilli,1WH7V@129337|Geobacillus	91061|Bacilli	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
ZZS2_k127_4005065_17	1197130.BAFM01000020_gene2812	1.783e-19	102.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVPQ@28890|Euryarchaeota,23TTF@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_4005065_10	871968.DESME_03115	1.966e-71	260.0	COG1012@1|root,COG1012@2|Bacteria,1UN2Y@1239|Firmicutes,25GVM@186801|Clostridia	186801|Clostridia	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
ZZS2_k127_4005065_15	28152.DJ57_2621	1.076e-50	183.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,41FXN@629|Yersinia	1236|Gammaproteobacteria	H	synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
ZZS2_k127_4005065_0	648757.Rvan_1802	4.995e-169	562.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QVKE@1224|Proteobacteria,2U21Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
ZZS2_k127_4005065_7	497964.CfE428DRAFT_4056	1.82e-78	270.0	COG2755@1|root,COG2755@2|Bacteria,46T12@74201|Verrucomicrobia	74201|Verrucomicrobia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_4005065_12	497964.CfE428DRAFT_0259	1.525e-56	204.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
ZZS2_k127_4005065_13	1499967.BAYZ01000028_gene1261	6.406e-54	209.0	COG0618@1|root,COG0618@2|Bacteria	2|Bacteria	S	phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS2_k127_4005065_9	56780.SYN_02762	1.276e-76	272.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
ZZS2_k127_4005065_11	1123399.AQVE01000002_gene2394	1.84e-59	214.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,463J2@72273|Thiotrichales	72273|Thiotrichales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4005065_5	1079460.ATTQ01000051_gene6378	3.047e-101	342.0	COG2041@1|root,COG2041@2|Bacteria,1QT0I@1224|Proteobacteria,2V9JK@28211|Alphaproteobacteria,4BGN1@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
ZZS2_k127_4005065_4	1123508.JH636440_gene2300	1.099e-108	357.0	COG1793@1|root,COG1793@2|Bacteria,2IYJZ@203682|Planctomycetes	203682|Planctomycetes	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_4005065_19	1303518.CCALI_01222	6.782e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_4017870_2	1396141.BATP01000043_gene1929	7.439e-69	269.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_4017870_7	313603.FB2170_10111	1.337e-51	212.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_4017870_4	452637.Oter_2645	9.787e-62	225.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,3K83I@414999|Opitutae	414999|Opitutae	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
ZZS2_k127_4017870_1	316067.Geob_3008	1.931e-90	314.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,43TMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
ZZS2_k127_4017870_3	909663.KI867150_gene711	1.051e-65	232.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
ZZS2_k127_4017870_5	231434.JQJH01000005_gene2189	7.278e-55	199.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,2TQYT@28211|Alphaproteobacteria,3N9N2@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	PFAM phosphate acetyl butaryl transferase	pta	-	2.3.1.19,2.3.1.8	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921,R01174	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
ZZS2_k127_4017870_10	34007.IT40_08585	1.66e-05	52.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_4,TPR_7,TPR_8
ZZS2_k127_4017870_9	1267533.KB906733_gene3472	4.794e-08	65.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
ZZS2_k127_4017870_8	452637.Oter_2422	8.436e-51	186.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_4017870_0	452637.Oter_1389	7.088e-158	540.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_4017870_6	234267.Acid_6845	2.348e-54	211.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria,3Y83C@57723|Acidobacteria	57723|Acidobacteria	I	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
ZZS2_k127_4038461_0	240016.ABIZ01000001_gene1559	1.456e-225	709.0	COG4102@1|root,COG4102@2|Bacteria,46UQM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_4038461_3	555779.Dthio_PD3586	4.636e-18	96.0	28Z54@1|root,2ZKXF@2|Bacteria,1RAVB@1224|Proteobacteria,430BX@68525|delta/epsilon subdivisions,2WVWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4038461_2	886293.Sinac_5315	5.403e-28	127.0	COG0682@1|root,COG0682@2|Bacteria,2IZQ2@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT,PDZ
ZZS2_k127_4038461_1	497964.CfE428DRAFT_0929	1.265e-138	470.0	COG4258@1|root,COG4258@2|Bacteria,46TC6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
ZZS2_k127_4050970_0	1396141.BATP01000018_gene1531	1.253e-26	129.0	COG2133@1|root,COG2755@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,46VBR@74201|Verrucomicrobia,2IUWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF1800,DUF5011,PA14
ZZS2_k127_4050970_3	452637.Oter_0852	1.364e-05	59.0	COG1520@1|root,COG3386@1|root,COG1520@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin,DUF4347,DUF5122,He_PIG,I-set,Ig_3,Laminin_G_3,Peptidase_S8
ZZS2_k127_4050970_1	1396141.BATP01000034_gene4198	1.055e-16	96.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_4050970_2	701176.VIBRN418_00851	1.139e-10	69.0	COG2244@1|root,COG2244@2|Bacteria,1NWFA@1224|Proteobacteria,1SNWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_40517_4	497964.CfE428DRAFT_4864	4.194e-37	144.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_40517_2	1396141.BATP01000024_gene780	3.413e-49	188.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,2IU0G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 3	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_40517_6	589865.DaAHT2_0990	1.251e-11	79.0	2EU3E@1|root,33MK8@2|Bacteria,1NMD9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_40517_3	204669.Acid345_4136	4.552e-43	183.0	COG3055@1|root,COG3055@2|Bacteria,3Y5BB@57723|Acidobacteria	57723|Acidobacteria	N	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
ZZS2_k127_40517_5	292564.Cyagr_1101	2.878e-30	141.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF4214,DUF4347,HemolysinCabind
ZZS2_k127_40517_1	1121897.AUGO01000002_gene2177	2.372e-53	214.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_40517_0	1156935.QWE_19483	3.106e-82	299.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS2_k127_40517_7	264203.ZMO1976	0.0004719	48.0	2BX7C@1|root,2ZB4P@2|Bacteria,1NSDF@1224|Proteobacteria,2U03Z@28211|Alphaproteobacteria,2KEX4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4073481_0	530564.Psta_1455	4.897e-302	957.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWZR@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_4073481_2	1123508.JH636444_gene5364	2.524e-157	503.0	COG1082@1|root,COG1082@2|Bacteria,2IXRD@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_4073481_4	497964.CfE428DRAFT_1842	5.37e-144	462.0	COG1082@1|root,COG1082@2|Bacteria,46U2S@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_4073481_6	595460.RRSWK_00476	1.809e-09	63.0	COG5487@1|root,COG5487@2|Bacteria,2J16P@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
ZZS2_k127_4073481_1	497964.CfE428DRAFT_1519	1.302e-161	520.0	COG2204@1|root,COG2204@2|Bacteria,46SFT@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_4073481_5	497964.CfE428DRAFT_1517	2.832e-135	452.0	COG5002@1|root,COG5002@2|Bacteria,46SJH@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_4073481_3	756272.Plabr_0280	6.056e-147	479.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_4077394_1	485913.Krac_2885	2.158e-13	74.0	COG2355@1|root,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_4077394_0	1040989.AWZU01000001_gene5816	8.296e-82	294.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,3JUPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
ZZS2_k127_4094234_3	867845.KI911784_gene1260	1.834e-42	181.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
ZZS2_k127_4094234_2	1121904.ARBP01000001_gene5577	3.027e-69	246.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_4094234_4	1209989.TepiRe1_0812	3.157e-07	54.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,42FW8@68295|Thermoanaerobacterales	186801|Clostridia	G	glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,Big_4,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM
ZZS2_k127_4094234_0	595460.RRSWK_05060	4.894e-148	480.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_4094234_1	1123248.KB893381_gene962	2.451e-88	306.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4P2AE@976|Bacteroidetes	976|Bacteroidetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_4102747_0	1123248.KB893321_gene465	2.984e-242	772.0	COG2133@1|root,COG3291@1|root,COG3391@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NF7B@976|Bacteroidetes,1IWJV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
ZZS2_k127_4102747_3	1173025.GEI7407_1016	5.198e-87	322.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_4102747_4	583355.Caka_2246	1.518e-35	142.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,3K9P3@414999|Opitutae	414999|Opitutae	S	PFAM nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
ZZS2_k127_4102747_1	555079.Toce_1427	3.479e-180	581.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
ZZS2_k127_4102747_2	497964.CfE428DRAFT_4748	2.073e-92	312.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS2_k127_4118857_6	314230.DSM3645_20252	7.738e-51	193.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
ZZS2_k127_4118857_7	926569.ANT_14530	8.367e-15	82.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ZZS2_k127_4118857_8	886293.Sinac_5236	7.56e-10	68.0	2EH81@1|root,33AZW@2|Bacteria,2J1J2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4118857_3	497964.CfE428DRAFT_2689	2.171e-105	364.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	3.1.3.3,3.5.1.28	ko:K01448,ko:K07315,ko:K21470	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03021,ko03036	-	-	-	-
ZZS2_k127_4118857_0	497964.CfE428DRAFT_2683	1.102e-265	842.0	COG5426@1|root,COG5426@2|Bacteria,46U69@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4118857_2	497964.CfE428DRAFT_2682	5.192e-107	374.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Big_3_3,CARDB,DUF11,GSDH,Glyco_hyd_65N_2,Laminin_G_3,SdrD_B
ZZS2_k127_4118857_4	497964.CfE428DRAFT_2681	4.333e-71	267.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_4118857_5	1123508.JH636439_gene737	3.718e-67	239.0	COG1409@1|root,COG1409@2|Bacteria	1123508.JH636439_gene737|-	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4118857_1	497964.CfE428DRAFT_5266	8.76e-172	548.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4140033_0	204669.Acid345_4052	6.851e-175	556.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
ZZS2_k127_4140033_1	1396141.BATP01000007_gene5629	2.484e-96	331.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS2_k127_4140033_2	1123242.JH636435_gene2487	4.056e-13	73.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_4146373_0	497964.CfE428DRAFT_0777	3.578e-183	597.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_4146373_1	452637.Oter_0699	4.907e-146	479.0	COG0617@1|root,COG0617@2|Bacteria,46UER@74201|Verrucomicrobia,3K732@414999|Opitutae	414999|Opitutae	J	Polynucleotide adenylyltransferase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
ZZS2_k127_4146373_3	530564.Psta_0778	7.665e-40	151.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
ZZS2_k127_4146373_2	1210884.HG799468_gene13605	9.253e-94	319.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
ZZS2_k127_4146373_4	237368.SCABRO_03851	7.324e-17	92.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_4160707_5	794903.OPIT5_04195	1.575e-28	117.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia,3K8C2@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
ZZS2_k127_4160707_4	452637.Oter_1291	1.13e-33	132.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia,3K89K@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
ZZS2_k127_4160707_1	794903.OPIT5_04205	1.381e-144	468.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
ZZS2_k127_4160707_2	1027273.GZ77_23130	2.548e-94	314.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1XJD9@135619|Oceanospirillales	135619|Oceanospirillales	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
ZZS2_k127_4160707_6	452637.Oter_1293	7.415e-27	117.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia,3K8AE@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
ZZS2_k127_4160707_3	794903.OPIT5_04215	1.578e-38	147.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia,3K8BF@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
ZZS2_k127_4160707_0	452637.Oter_1295	8.549e-199	631.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia,3K7HF@414999|Opitutae	414999|Opitutae	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
ZZS2_k127_4165916_1	102232.GLO73106DRAFT_00016540	1.463e-34	154.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	yvnB	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	LTD,Metallophos,PAP2,VCBS
ZZS2_k127_4165916_0	211165.AJLN01000055_gene4564	8.43e-57	201.0	COG0454@1|root,COG0456@2|Bacteria,1G6UC@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
ZZS2_k127_4177260_4	1120972.AUMH01000001_gene1232	6.084e-36	142.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,278CC@186823|Alicyclobacillaceae	91061|Bacilli	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
ZZS2_k127_4177260_1	234267.Acid_6138	6.041e-129	435.0	COG0457@1|root,COG2010@1|root,COG0457@2|Bacteria,COG2010@2|Bacteria,3Y67F@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
ZZS2_k127_4177260_2	1123070.KB899259_gene1974	2.342e-121	412.0	COG3276@1|root,COG3276@2|Bacteria	2|Bacteria	J	selenocysteine insertion sequence binding	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
ZZS2_k127_4177260_0	497964.CfE428DRAFT_2113	0.0	1129.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46UX1@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_4177260_6	1089553.Tph_c13300	2.499e-19	93.0	COG0730@1|root,COG0730@2|Bacteria,1VAMI@1239|Firmicutes,24MXA@186801|Clostridia,42GYA@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS2_k127_4177260_5	42256.RradSPS_1127	2.564e-30	130.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
ZZS2_k127_4177260_3	1403819.BATR01000178_gene5961	1.301e-39	165.0	COG0526@1|root,COG0526@2|Bacteria,46VHM@74201|Verrucomicrobia,2IVZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_4206653_1	1403819.BATR01000062_gene1907	1.356e-105	351.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4206653_0	561175.KB894097_gene319	1.214e-125	416.0	COG0635@1|root,COG0635@2|Bacteria,2GJ2W@201174|Actinobacteria,4EHG2@85012|Streptosporangiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ZZS2_k127_4206653_2	530564.Psta_0141	9.015e-98	326.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Sulfatase
ZZS2_k127_4206653_7	105425.BBPL01000004_gene7564	8.3e-18	91.0	COG1011@1|root,COG1011@2|Bacteria,2GMZT@201174|Actinobacteria,2NFRG@228398|Streptacidiphilus	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	3.1.3.5	ko:K07025,ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase_like
ZZS2_k127_4206653_5	269800.Tfu_0737	2.315e-66	240.0	COG0189@1|root,COG0189@2|Bacteria,2GQ9B@201174|Actinobacteria,4EI9K@85012|Streptosporangiales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4206653_3	530564.Psta_0138	1.801e-97	333.0	COG3831@1|root,COG4886@1|root,COG3831@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,WGR
ZZS2_k127_4206653_4	530564.Psta_0139	2.358e-88	302.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	HtaA
ZZS2_k127_4206653_6	684949.ATTJ01000003_gene3292	1.475e-26	115.0	2B4Q9@1|root,31XGJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4222025_0	497964.CfE428DRAFT_3316	9.456e-228	711.0	COG0673@1|root,COG0673@2|Bacteria,46S77@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_4222025_1	497964.CfE428DRAFT_0801	1.323e-119	392.0	COG4586@1|root,COG4586@2|Bacteria,46TXF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_4255999_4	886293.Sinac_0380	2.359e-56	201.0	COG3391@1|root,COG3391@2|Bacteria,2IYVS@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
ZZS2_k127_4255999_0	344747.PM8797T_05570	3.366e-136	448.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
ZZS2_k127_4255999_2	452637.Oter_0444	1.116e-102	355.0	COG1345@1|root,COG1345@2|Bacteria,46U2K@74201|Verrucomicrobia,3K76A@414999|Opitutae	414999|Opitutae	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
ZZS2_k127_4255999_7	278957.ABEA03000033_gene947	1.663e-18	94.0	2EI2N@1|root,33BU2@2|Bacteria,46WEF@74201|Verrucomicrobia,3K8D4@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4255999_6	794903.OPIT5_25095	4.039e-25	109.0	COG1516@1|root,COG1516@2|Bacteria,46WPJ@74201|Verrucomicrobia,3K8AQ@414999|Opitutae	414999|Opitutae	N	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
ZZS2_k127_4255999_5	648885.KB316282_gene273	4.068e-30	134.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JRVE@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM response regulator receiver	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg,dCache_1
ZZS2_k127_4255999_1	452637.Oter_0430	9.75e-112	377.0	COG3437@1|root,COG3437@2|Bacteria,46UU1@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
ZZS2_k127_4255999_3	1123508.JH636439_gene1391	8.424e-78	287.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_4255999_8	382464.ABSI01000016_gene728	6.204e-11	63.0	COG1344@1|root,COG1344@2|Bacteria,46VC5@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_N
ZZS2_k127_4260133_0	497964.CfE428DRAFT_3394	7.556e-125	409.0	COG0275@1|root,COG0275@2|Bacteria,46UK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	MraW methylase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_5
ZZS2_k127_4260133_1	1396141.BATP01000040_gene2146	2.295e-107	389.0	2DUKG@1|root,33R4D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4268604_5	743299.Acife_0999	4.915e-34	141.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,1S4W5@1236|Gammaproteobacteria,2NDNC@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
ZZS2_k127_4268604_1	1173026.Glo7428_4404	7.504e-142	464.0	COG0438@1|root,COG0438@2|Bacteria,1G0ZR@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_4268604_2	1173025.GEI7407_1830	1.861e-108	366.0	COG0438@1|root,COG0438@2|Bacteria,1G271@1117|Cyanobacteria,1H9H0@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase 4-like domain	icsA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_4268604_0	56107.Cylst_3245	5.655e-199	647.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1HM11@1161|Nostocales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_4268604_10	1449044.JMLE01000003_gene2878	7.043e-06	57.0	COG3173@1|root,COG3173@2|Bacteria,2GZAV@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS2_k127_4268604_4	1131269.AQVV01000015_gene2032	1.25e-49	192.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_4268604_7	1203606.HMPREF1526_00005	2.148e-12	78.0	COG0500@1|root,COG2226@2|Bacteria,1TR7I@1239|Firmicutes,24FG4@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_4268604_3	118168.MC7420_7993	2.016e-93	324.0	COG0510@1|root,COG0510@2|Bacteria,1G023@1117|Cyanobacteria,1HEZ0@1150|Oscillatoriales	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS2_k127_4268604_9	402881.Plav_2325	1.333e-09	71.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,1JPZE@119043|Rhodobiaceae	28211|Alphaproteobacteria	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PAP2,PATR,Peptidase_S8
ZZS2_k127_4268604_8	886293.Sinac_7082	7.886e-11	72.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
ZZS2_k127_4268604_6	1183438.GKIL_3929	7.913e-15	76.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_4319533_3	314230.DSM3645_20627	2.169e-107	363.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4319533_1	1123242.JH636434_gene4152	3.547e-195	613.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_4319533_5	497964.CfE428DRAFT_0238	2.352e-22	102.0	COG2010@1|root,COG2010@2|Bacteria,46TSG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_4319533_4	1118054.CAGW01000017_gene4422	9.425e-68	238.0	COG0274@1|root,COG1051@1|root,COG0274@2|Bacteria,COG1051@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,26QH3@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835,iYO844.BSU39420	DeoC
ZZS2_k127_4319533_6	761193.Runsl_3450	0.0001021	52.0	COG1017@1|root,COG1017@2|Bacteria,4NS54@976|Bacteroidetes,47QWP@768503|Cytophagia	976|Bacteroidetes	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	Globin
ZZS2_k127_4319533_0	452637.Oter_2327	3.193e-222	712.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4319533_2	314230.DSM3645_20627	1.466e-136	454.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4328247_7	886293.Sinac_3768	1.443e-60	218.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
ZZS2_k127_4328247_2	234267.Acid_2132	9.832e-101	334.0	COG1028@1|root,COG1028@2|Bacteria,3Y7BE@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_4328247_3	696369.KI912183_gene2345	8.546e-99	329.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,263ZF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	iHN637.CLJU_RS07630	MIP
ZZS2_k127_4328247_9	1382356.JQMP01000001_gene969	1.562e-49	186.0	COG0451@1|root,COG0451@2|Bacteria,2G8UV@200795|Chloroflexi,27Z0H@189775|Thermomicrobia	189775|Thermomicrobia	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ZZS2_k127_4328247_0	497964.CfE428DRAFT_6409	9.146e-246	833.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
ZZS2_k127_4328247_10	497964.CfE428DRAFT_5185	1.18e-17	84.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS2_k127_4328247_8	386456.JQKN01000013_gene2982	8.486e-54	199.0	arCOG01788@1|root,arCOG01788@2157|Archaea,2XXVU@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
ZZS2_k127_4328247_1	478741.JAFS01000002_gene868	1.461e-215	681.0	COG0119@1|root,COG0119@2|Bacteria,46TQ5@74201|Verrucomicrobia,37G4P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
ZZS2_k127_4328247_6	497964.CfE428DRAFT_5015	6.42e-63	224.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
ZZS2_k127_4328247_5	398767.Glov_1317	2.277e-83	287.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
ZZS2_k127_4328247_4	479434.Sthe_2195	2.218e-91	309.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,27Z0A@189775|Thermomicrobia	189775|Thermomicrobia	H	Quinolinate phosphoribosyl transferase, N-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
ZZS2_k127_4340384_2	945713.IALB_2577	6.505e-80	294.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
ZZS2_k127_4340384_0	1396418.BATQ01000097_gene5973	5.221e-136	460.0	COG0671@1|root,COG1807@1|root,COG0671@2|Bacteria,COG1807@2|Bacteria,46SSE@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PMT_2
ZZS2_k127_4340384_3	497964.CfE428DRAFT_5454	8.516e-59	214.0	COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	8-oxoguanine DNA glycosylase, N-terminal domain	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
ZZS2_k127_4340384_4	382464.ABSI01000010_gene3771	1.254e-25	113.0	2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4340384_1	1396141.BATP01000022_gene290	3.212e-86	298.0	COG4324@1|root,COG4324@2|Bacteria,46TKK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
ZZS2_k127_4361002_1	497964.CfE428DRAFT_0275	5.409e-120	396.0	COG1879@1|root,COG1879@2|Bacteria,46W7Q@74201|Verrucomicrobia	2|Bacteria	G	PFAM periplasmic binding protein LacI transcriptional regulator	rbsB	-	-	ko:K10439,ko:K10543	ko02010,ko02030,map02010,map02030	M00212,M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4	-	-	Peripla_BP_4
ZZS2_k127_4361002_2	344747.PM8797T_11389	1.688e-116	385.0	COG1172@1|root,COG1172@2|Bacteria,2IZWQ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K10559,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
ZZS2_k127_4361002_8	1396141.BATP01000003_gene5168	6.031e-31	136.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4361002_5	215803.DB30_7610	3.281e-49	205.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
ZZS2_k127_4361002_4	1437605.BACT_1329	5.327e-51	211.0	COG5184@1|root,COG5184@2|Bacteria,2IG31@201174|Actinobacteria,4D0NM@85004|Bifidobacteriales	201174|Actinobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Pkinase,RCC1
ZZS2_k127_4361002_9	1123070.KB899256_gene2193	6.855e-12	81.0	COG2730@1|root,COG2931@1|root,COG3209@1|root,COG3266@1|root,COG5184@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3266@2|Bacteria,COG5184@2|Bacteria,46S8F@74201|Verrucomicrobia,2IV48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
ZZS2_k127_4361002_7	1121396.KB892901_gene2171	1.167e-34	156.0	COG1409@1|root,COG3291@1|root,COG4733@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1QZGY@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,DUF839,Exo_endo_phos,PKD
ZZS2_k127_4361002_0	243090.RB4667	1.817e-145	475.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4361002_3	743719.PaelaDRAFT_3973	7.555e-57	209.0	COG2207@1|root,COG2207@2|Bacteria,1VIQW@1239|Firmicutes,4IR31@91061|Bacilli,26XKY@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS2_k127_4361002_6	1121878.AUGL01000017_gene1759	2.056e-35	143.0	2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4361002_10	1210884.HG799466_gene12379	3.657e-05	46.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4393460_1	479434.Sthe_0586	1.03e-35	157.0	COG3266@1|root,COG3266@2|Bacteria,2GBHM@200795|Chloroflexi,27Y68@189775|Thermomicrobia	189775|Thermomicrobia	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_4393460_0	84531.JMTZ01000023_gene4233	8.37e-96	351.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1X499@135614|Xanthomonadales	1236|Gammaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
ZZS2_k127_44100_6	452637.Oter_0382	4.521e-81	276.0	COG2041@1|root,COG2041@2|Bacteria,46TCM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
ZZS2_k127_44100_4	646529.Desaci_3461	2.13e-106	357.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_44100_3	1396141.BATP01000060_gene4642	3.775e-127	416.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
ZZS2_k127_44100_2	1156937.MFUM_1020128	1.075e-134	451.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,37GCJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
ZZS2_k127_44100_5	497964.CfE428DRAFT_2551	1.943e-94	312.0	COG0279@1|root,COG0279@2|Bacteria,46TRG@74201|Verrucomicrobia	74201|Verrucomicrobia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
ZZS2_k127_44100_10	1408306.JHXX01000002_gene3082	1.505e-62	223.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,4BWHC@830|Butyrivibrio	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
ZZS2_k127_44100_11	1192034.CAP_5621	6.72e-55	221.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
ZZS2_k127_44100_0	1121346.KB899817_gene3149	5.472e-304	944.0	COG0129@1|root,COG0129@2|Bacteria,1U56J@1239|Firmicutes,4HD31@91061|Bacilli,26U7U@186822|Paenibacillaceae	91061|Bacilli	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
ZZS2_k127_44100_12	857087.Metme_3901	3.055e-25	124.0	COG2202@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
ZZS2_k127_44100_7	1396141.BATP01000025_gene978	9.117e-79	299.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_44100_9	1396141.BATP01000025_gene980	4.22e-65	238.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_44100_8	452637.Oter_1311	2.759e-78	270.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_44100_1	497964.CfE428DRAFT_0072	9.208e-217	681.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
ZZS2_k127_4441127_1	111781.Lepto7376_0105	7.246e-23	117.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
ZZS2_k127_4441127_0	382464.ABSI01000010_gene3258	0.0	1080.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4480283_1	644283.Micau_3865	5.602e-21	111.0	COG0823@1|root,COG2304@1|root,COG3292@1|root,COG3391@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,2I71F@201174|Actinobacteria,4DKYH@85008|Micromonosporales	201174|Actinobacteria	T	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4480283_2	378806.STAUR_5069	5.192e-15	91.0	COG0747@1|root,COG0747@2|Bacteria,1QX9G@1224|Proteobacteria,43C2P@68525|delta/epsilon subdivisions,2X7D9@28221|Deltaproteobacteria,2Z3FQ@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36,REJ
ZZS2_k127_4480283_0	102125.Xen7305DRAFT_00020060	2.354e-53	218.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
ZZS2_k127_4480283_3	864069.MicloDRAFT_00008560	6.203e-10	68.0	COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,2TVH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG1226 Kef-type K transport systems	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,cNMP_binding
ZZS2_k127_4541636_13	1121335.Clst_1151	3.237e-32	128.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ZZS2_k127_4541636_17	1026882.MAMP_03073	5.85e-06	60.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales	72273|Thiotrichales	M	PFAM AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
ZZS2_k127_4541636_16	1125863.JAFN01000001_gene1816	1.943e-06	62.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
ZZS2_k127_4541636_9	497964.CfE428DRAFT_4864	6.356e-57	207.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4541636_14	1121430.JMLG01000019_gene1642	9.177e-17	90.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4541636_4	1403819.BATR01000041_gene1221	6.385e-116	384.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS2_k127_4541636_5	1232410.KI421412_gene357	2.338e-113	377.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,43TDI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
ZZS2_k127_4541636_7	28444.JODQ01000003_gene4751	2.926e-71	247.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4EIDE@85012|Streptosporangiales	201174|Actinobacteria	S	Possible lysine decarboxylase	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS2_k127_4541636_6	1121468.AUBR01000030_gene1251	1.715e-110	375.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42FM5@68295|Thermoanaerobacterales	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
ZZS2_k127_4541636_1	497964.CfE428DRAFT_0139	6.535e-173	549.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_4541636_0	478741.JAFS01000002_gene105	1.179e-188	605.0	COG1222@1|root,COG1222@2|Bacteria,46UBC@74201|Verrucomicrobia,37GE5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Proteasomal ATPase OB/ID domain	-	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
ZZS2_k127_4541636_2	1156937.MFUM_60015	6.444e-159	516.0	COG4122@1|root,COG4122@2|Bacteria,46TEU@74201|Verrucomicrobia,37G25@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Pup-ligase protein	-	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
ZZS2_k127_4541636_8	497964.CfE428DRAFT_3467	1.499e-65	235.0	COG0638@1|root,COG0638@2|Bacteria,46UC7@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Proteasome subunit	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
ZZS2_k127_4541636_11	497964.CfE428DRAFT_3466	2.1e-48	186.0	COG0638@1|root,COG0638@2|Bacteria,46VYB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Proteasome subunit	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
ZZS2_k127_4541636_3	481448.Minf_1278	2.24e-132	436.0	COG4122@1|root,COG4122@2|Bacteria,46TZ5@74201|Verrucomicrobia,37G77@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Pup-ligase protein	-	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
ZZS2_k127_4541636_15	794903.OPIT5_00805	8.372e-07	56.0	2A1I4@1|root,30PRV@2|Bacteria,46XXK@74201|Verrucomicrobia,3K8JP@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4541636_10	452637.Oter_4178	2.66e-53	203.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia,3K7SM@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4541636_12	443144.GM21_0540	9.535e-46	170.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,437IE@68525|delta/epsilon subdivisions,2WVS2@28221|Deltaproteobacteria,43VBF@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
ZZS2_k127_4545711_1	1396141.BATP01000060_gene4765	5.656e-17	95.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_4545711_0	344747.PM8797T_10974	3.596e-66	248.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_4581007_3	497964.CfE428DRAFT_4900	5.832e-81	279.0	COG1442@1|root,COG1442@2|Bacteria	2|Bacteria	M	lipopolysaccharide 3-alpha-galactosyltransferase activity	kdsB2	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8,Glycos_transf_2
ZZS2_k127_4581007_6	246197.MXAN_0299	3.799e-17	93.0	COG1940@1|root,COG1940@2|Bacteria,1QARE@1224|Proteobacteria,43596@68525|delta/epsilon subdivisions,2X971@28221|Deltaproteobacteria,2Z2B2@29|Myxococcales	28221|Deltaproteobacteria	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4581007_0	452637.Oter_0935	3.214e-168	537.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
ZZS2_k127_4581007_5	880072.Desac_1280	9.858e-52	196.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ZZS2_k127_4581007_1	886293.Sinac_4912	3.294e-142	463.0	COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes	203682|Planctomycetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS2_k127_4581007_2	1173022.Cri9333_4499	6.03e-92	310.0	COG0363@1|root,COG0363@2|Bacteria,1G1M9@1117|Cyanobacteria,1HACM@1150|Oscillatoriales	1117|Cyanobacteria	G	6-phosphogluconolactonase glucosamine-6-phosphate isomerase deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
ZZS2_k127_4581007_4	378806.STAUR_1528	3.91e-52	195.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
ZZS2_k127_4594922_2	1123242.JH636435_gene944	2.197e-125	420.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4594922_0	886293.Sinac_0402	1.296e-219	734.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4594922_3	497964.CfE428DRAFT_0837	1.214e-47	179.0	COG2947@1|root,COG2947@2|Bacteria,46VWG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
ZZS2_k127_4594922_4	580327.Tthe_0144	3.262e-34	139.0	COG0637@1|root,COG0637@2|Bacteria,1V1NW@1239|Firmicutes,24G37@186801|Clostridia,42G6E@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,HAD_2
ZZS2_k127_4594922_1	1121428.DESHY_20160___1	6.492e-203	655.0	COG4147@1|root,COG4147@2|Bacteria,1V2SK@1239|Firmicutes,25DGS@186801|Clostridia,264G7@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
ZZS2_k127_462683_3	192952.MM_3157	1.04e-124	417.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
ZZS2_k127_462683_4	118168.MC7420_150	5.434e-119	394.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_462683_1	234267.Acid_2664	8.894e-208	664.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
ZZS2_k127_462683_8	862908.BMS_2427	6.617e-29	123.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,42VV6@68525|delta/epsilon subdivisions,2MT87@213481|Bdellovibrionales,2WS0G@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
ZZS2_k127_462683_7	1379698.RBG1_1C00001G0217	6.269e-60	237.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
ZZS2_k127_462683_11	1443113.LC20_02722	0.0003365	45.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_462683_10	96561.Dole_2271	3.761e-07	55.0	COG3668@1|root,COG3668@2|Bacteria,1N8DJ@1224|Proteobacteria,42VZU@68525|delta/epsilon subdivisions,2WRB9@28221|Deltaproteobacteria,2MM4U@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_462683_0	1123508.JH636448_gene7669	2.651e-217	680.0	COG4948@1|root,COG4948@2|Bacteria,2IY40@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase muconate lactonizing enzyme	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_462683_2	886293.Sinac_2740	4.426e-163	527.0	COG3356@1|root,COG3356@2|Bacteria,2J4VF@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
ZZS2_k127_462683_5	344747.PM8797T_00709	1.991e-107	363.0	COG2271@1|root,COG2271@2|Bacteria,2IYAW@203682|Planctomycetes	203682|Planctomycetes	G	Major facilitator superfamily	-	-	-	ko:K03535,ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.1,2.A.1.14.7	-	-	MFS_1
ZZS2_k127_462683_6	314230.DSM3645_18601	6.976e-105	350.0	COG0329@1|root,COG0329@2|Bacteria,2IX60@203682|Planctomycetes	203682|Planctomycetes	EM	COG0329 Dihydrodipicolinate synthase N-acetylneuraminate lyase	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS2_k127_4631062_0	1123242.JH636434_gene3727	5.898e-90	340.0	COG1450@1|root,COG1450@2|Bacteria,2IX4B@203682|Planctomycetes	203682|Planctomycetes	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_4631062_1	1210884.HG799465_gene11644	0.0008754	49.0	2EQDK@1|root,33HZN@2|Bacteria,2J1FY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4638153_20	1397527.Q670_02705	2.117e-08	61.0	COG3637@1|root,COG3637@2|Bacteria,1NE9Q@1224|Proteobacteria,1T3ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4638153_1	1403819.BATR01000112_gene3806	1.078e-228	721.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ZZS2_k127_4638153_5	243233.MCA2756	1.508e-138	450.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
ZZS2_k127_4638153_2	314278.NB231_11354	1.858e-169	544.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales	1236|Gammaproteobacteria	E	PFAM Aminotransferase class-III	-	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0048037,GO:0070279,GO:0070280,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	Aminotran_3
ZZS2_k127_4638153_9	243233.MCA2757	1.376e-69	246.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
ZZS2_k127_4638153_16	251221.35212647	8.591e-19	93.0	2E3RZ@1|root,32YPK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4638153_6	879212.DespoDRAFT_03479	1.396e-136	444.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ZZS2_k127_4638153_12	983545.Glaag_4028	7.66e-47	176.0	COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,466VF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	VPA0371	-	-	-	-	-	-	-	-	-	-	-	Ysc84
ZZS2_k127_4638153_14	583355.Caka_1288	6.039e-23	104.0	2AG8J@1|root,316DU@2|Bacteria,46WFQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4638153_10	1048983.EL17_04325	1.577e-64	239.0	COG4775@1|root,COG4775@2|Bacteria,4NMIQ@976|Bacteroidetes,47PGI@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
ZZS2_k127_4638153_7	1449049.JONW01000013_gene4657	4.619e-114	398.0	COG5164@1|root,COG5164@2|Bacteria,1MX1Z@1224|Proteobacteria,2TWHE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4638153_11	443598.AUFA01000051_gene28	2.447e-58	222.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
ZZS2_k127_4638153_3	452637.Oter_3627	4.644e-161	524.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,3K7MJ@414999|Opitutae	414999|Opitutae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
ZZS2_k127_4638153_13	756272.Plabr_4453	2.782e-42	161.0	COG3685@1|root,COG3685@2|Bacteria,2IZRW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
ZZS2_k127_4638153_15	1282361.ABAC402_18760	2.196e-19	91.0	COG1396@1|root,COG1396@2|Bacteria,1N8D1@1224|Proteobacteria,2UHRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
ZZS2_k127_4638153_8	1121451.DESAM_20310	5.956e-89	308.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,42R7H@68525|delta/epsilon subdivisions,2WMU0@28221|Deltaproteobacteria,2MB3N@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	HipA domain protein	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
ZZS2_k127_4638153_4	886293.Sinac_3265	2.806e-154	505.0	COG1620@1|root,COG1620@2|Bacteria,2IWWM@203682|Planctomycetes	203682|Planctomycetes	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
ZZS2_k127_4638153_0	1340493.JNIF01000003_gene1440	0.0	1036.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
ZZS2_k127_4638153_17	266264.Rmet_4082	3.667e-18	87.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
ZZS2_k127_4638153_18	521674.Plim_4045	1.711e-16	94.0	2CGJ6@1|root,31UKG@2|Bacteria,2J1GT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4643239_4	497964.CfE428DRAFT_5491	4.198e-19	89.0	COG0657@1|root,COG0657@2|Bacteria,46SVI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
ZZS2_k127_4643239_7	903818.KI912269_gene146	2.989e-07	64.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Flg_new
ZZS2_k127_4643239_0	1173026.Glo7428_2160	4.781e-134	429.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_4643239_2	1121957.ATVL01000013_gene61	5.289e-110	404.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
ZZS2_k127_4643239_3	313596.RB2501_08810	6.033e-24	121.0	COG2885@1|root,COG4886@1|root,COG2885@2|Bacteria,COG4886@2|Bacteria,4NF17@976|Bacteroidetes,1IJNI@117743|Flavobacteriia	976|Bacteroidetes	O	Mycoplasma protein of unknown function, DUF285	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF285,LRR_5
ZZS2_k127_4643239_1	215803.DB30_7610	5.399e-124	449.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
ZZS2_k127_4643239_5	1038860.AXAP01000025_gene1636	2.315e-17	86.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,3K039@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS2_k127_4643239_8	316067.Geob_1895	1.215e-05	55.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,42UQA@68525|delta/epsilon subdivisions,2WQXF@28221|Deltaproteobacteria,43TDQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_464762_2	72004.XP_005895200.1	2.562e-05	55.0	KOG3588@1|root,KOG3588@2759|Eukaryota,38GHI@33154|Opisthokonta,3BG1U@33208|Metazoa,3CU4Y@33213|Bilateria,480Q7@7711|Chordata,48XWZ@7742|Vertebrata,3J2RD@40674|Mammalia,4JC2Z@91561|Cetartiodactyla	33208|Metazoa	G	Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans	B4GALNT4	GO:0003674,GO:0003824,GO:0008194,GO:0008376,GO:0016740,GO:0016757,GO:0016758	2.4.1.244	ko:K09656,ko:K09657	ko00513,ko01100,map00513,map01100	-	R07610,R07611	-	ko00000,ko00001,ko01000,ko01003	-	GT7	-	CHGN,PA14
ZZS2_k127_464762_1	452637.Oter_3065	1.404e-52	213.0	COG0823@1|root,COG3210@1|root,COG5276@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3739,Germane,Gmad1,Haemagg_act,LVIVD
ZZS2_k127_464762_0	411901.BACCAC_00949	4.773e-55	199.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,2FQ5W@200643|Bacteroidia,4AN28@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.82	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
ZZS2_k127_464762_3	497964.CfE428DRAFT_1773	0.0006801	49.0	COG2197@1|root,COG4585@1|root,COG2197@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K07693,ko:K20971	ko02020,ko02025,map02020,map02025	M00479	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA_3,MASE1,Response_reg
ZZS2_k127_4649741_8	1232437.KL662010_gene1640	1.476e-08	67.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2MN1B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4649741_2	1396418.BATQ01000049_gene423	4.389e-195	621.0	COG3356@1|root,COG3356@2|Bacteria,46UGT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4649741_0	497964.CfE428DRAFT_4244	0.0	1106.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TVM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_4649741_6	886293.Sinac_1051	1.953e-58	230.0	COG0515@1|root,COG0515@2|Bacteria,2IY6U@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_4649741_1	1396141.BATP01000042_gene1907	1.462e-218	689.0	COG3391@1|root,COG3391@2|Bacteria,46WEM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
ZZS2_k127_4649741_4	1396141.BATP01000042_gene1906	1.823e-70	245.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
ZZS2_k127_4649741_7	1095769.CAHF01000006_gene1856	7.391e-58	205.0	COG5637@1|root,COG5637@2|Bacteria,1RCEX@1224|Proteobacteria,2VQP4@28216|Betaproteobacteria,4771P@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
ZZS2_k127_4649741_5	1278073.MYSTI_01573	1.056e-62	226.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS2_k127_4649741_3	243090.RB2837	6.647e-187	603.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4676791_4	452637.Oter_0312	1.692e-11	76.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
ZZS2_k127_4676791_6	1280686.AUKE01000001_gene2115	6.513e-07	61.0	COG1595@1|root,COG2273@1|root,COG2755@1|root,COG1595@2|Bacteria,COG2273@2|Bacteria,COG2755@2|Bacteria,1UJPH@1239|Firmicutes,25F7M@186801|Clostridia	186801|Clostridia	G	PFAM coagulation factor 5 8 type	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
ZZS2_k127_4676791_1	1396141.BATP01000042_gene1928	1.444e-37	166.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_4676791_2	324057.Pjdr2_4676	3.021e-18	102.0	COG1409@1|root,COG3291@1|root,COG3537@1|root,COG3693@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG3537@2|Bacteria,COG3693@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26VY4@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92
ZZS2_k127_4676791_3	1232410.KI421418_gene2349	4.497e-14	88.0	COG2133@1|root,COG2755@1|root,COG3209@1|root,COG3866@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3209@2|Bacteria,COG3866@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
ZZS2_k127_4676791_0	1396141.BATP01000043_gene1929	2.934e-205	708.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_4676791_5	316067.Geob_1832	3.555e-08	61.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	mxcI	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	TIG
ZZS2_k127_4677037_7	497964.CfE428DRAFT_5311	1.887e-08	58.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_4677037_3	700598.Niako_5012	1.309e-38	168.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,ChW,SpoIID
ZZS2_k127_4677037_6	497964.CfE428DRAFT_5514	3.288e-10	74.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Lectin_legB,fn3
ZZS2_k127_4677037_5	1347368.HG964405_gene6101	6.563e-17	96.0	COG3391@1|root,COG4632@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	tagL	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Flg_new,NAGPA,SLH
ZZS2_k127_4677037_1	483219.LILAB_27650	1.296e-85	295.0	COG2374@1|root,COG2374@2|Bacteria,1RA34@1224|Proteobacteria,42XZM@68525|delta/epsilon subdivisions,2WT9C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
ZZS2_k127_4677037_4	1286632.P278_26300	1.157e-21	106.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
ZZS2_k127_4677037_2	497964.CfE428DRAFT_3461	3.663e-44	181.0	COG0457@1|root,COG0457@2|Bacteria,46SZM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
ZZS2_k127_4677037_0	1396141.BATP01000060_gene4695	2.438e-104	353.0	COG0546@1|root,COG1051@1|root,COG0546@2|Bacteria,COG1051@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
ZZS2_k127_4677037_8	748247.AZKH_p0180	0.000129	53.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808	FolB
ZZS2_k127_4688892_1	261292.Nit79A3_3310	9.305e-173	555.0	COG3540@1|root,COG3540@2|Bacteria,1PI5V@1224|Proteobacteria,2W6S3@28216|Betaproteobacteria,374GH@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
ZZS2_k127_4688892_2	933262.AXAM01000151_gene828	4.159e-143	473.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
ZZS2_k127_4688892_0	1198232.CYCME_0690	2.345e-249	784.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,45ZSA@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
ZZS2_k127_4688892_3	342610.Patl_1501	4.123e-23	109.0	COG0823@1|root,COG3209@1|root,COG3291@1|root,COG0823@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria,2Q5IF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD,REJ
ZZS2_k127_4690343_3	1396141.BATP01000003_gene5021	9.273e-107	348.0	COG2110@1|root,COG2110@2|Bacteria,46X8S@74201|Verrucomicrobia,2IV15@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
ZZS2_k127_4690343_2	452637.Oter_1389	1.35e-153	527.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_4690343_4	195253.Syn6312_3712	9.094e-38	165.0	COG1357@1|root,COG2319@1|root,COG3903@1|root,COG1357@2|Bacteria,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria,1GZQ3@1129|Synechococcus	1117|Cyanobacteria	M	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
ZZS2_k127_4690343_5	6500.XP_005104574.1	4.012e-05	58.0	KOG1836@1|root,KOG1836@2759|Eukaryota,38CQ0@33154|Opisthokonta,3B9B6@33208|Metazoa,3CTWN@33213|Bilateria	33208|Metazoa	W	regulation of embryonic development	-	GO:0000003,GO:0003006,GO:0005575,GO:0005576,GO:0005604,GO:0007275,GO:0007498,GO:0007502,GO:0007548,GO:0008150,GO:0008406,GO:0009888,GO:0022414,GO:0031012,GO:0032501,GO:0032502,GO:0035295,GO:0044421,GO:0045137,GO:0048513,GO:0048565,GO:0048608,GO:0048731,GO:0048856,GO:0055123,GO:0061458,GO:0062023	-	ko:K05637	ko04151,ko04510,ko04512,ko05145,ko05146,ko05165,ko05200,ko05222,map04151,map04510,map04512,map05145,map05146,map05165,map05200,map05222	-	-	-	ko00000,ko00001	-	-	-	Laminin_B,Laminin_EGF,Laminin_G_1,Laminin_G_2,Laminin_N
ZZS2_k127_4690343_1	1131812.JQMS01000001_gene2729	3.081e-158	554.0	COG2304@1|root,COG3391@1|root,COG5184@1|root,COG2304@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2NSCM@237|Flavobacterium	976|Bacteroidetes	O	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
ZZS2_k127_4690343_0	497964.CfE428DRAFT_1973	7.823e-210	661.0	COG1488@1|root,COG1488@2|Bacteria,46SAG@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
ZZS2_k127_4708697_1	886293.Sinac_2222	1.205e-228	719.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_4708697_0	886293.Sinac_2223	2.247e-287	924.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_4708697_2	497964.CfE428DRAFT_1931	1.49e-82	286.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_4719316_0	452637.Oter_2685	0.0	1349.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS2_k127_4719316_6	234267.Acid_7226	4.338e-89	301.0	COG3291@1|root,COG3291@2|Bacteria,3Y76G@57723|Acidobacteria	57723|Acidobacteria	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_4719316_3	497964.CfE428DRAFT_4366	9.375e-163	526.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_4719316_11	573061.Clocel_1966	3.923e-37	162.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_4719316_14	880073.Calab_3168	0.0005665	53.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	-
ZZS2_k127_4719316_4	1123242.JH636434_gene4080	8.04e-132	434.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4719316_1	1210884.HG799468_gene13690	1.325e-244	770.0	COG3653@1|root,COG3653@2|Bacteria,2IXWQ@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
ZZS2_k127_4719316_7	1210884.HG799474_gene15102	1.044e-64	242.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_4719316_9	1169143.KB911042_gene160	3.842e-44	165.0	COG1051@1|root,COG1051@2|Bacteria,1MZDA@1224|Proteobacteria,2VU61@28216|Betaproteobacteria,1K7MG@119060|Burkholderiaceae	28216|Betaproteobacteria	F	PFAM NUDIX hydrolase	-	-	-	ko:K03207	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
ZZS2_k127_4719316_2	330214.NIDE0582	9.533e-199	658.0	COG1752@1|root,COG3153@1|root,COG1752@2|Bacteria,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.59,2.3.1.82	ko:K14658,ko:K17840,ko:K18815	-	M00664	-	-	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Patatin
ZZS2_k127_4719316_5	1396418.BATQ01000144_gene3431	6.044e-113	396.0	COG0348@1|root,COG0348@2|Bacteria,46UK4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
ZZS2_k127_4719316_8	930169.B5T_01846	2.313e-51	208.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XHN2@135619|Oceanospirillales	135619|Oceanospirillales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ZZS2_k127_4719316_12	1198114.AciX9_1111	3.689e-21	100.0	COG4232@1|root,COG4232@2|Bacteria,3Y5CU@57723|Acidobacteria,2JJSZ@204432|Acidobacteriia	204432|Acidobacteriia	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
ZZS2_k127_4719316_10	1210884.HG799472_gene14912	2.977e-40	152.0	COG0607@1|root,COG0607@2|Bacteria,2IZWR@203682|Planctomycetes	203682|Planctomycetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_4736921_8	497964.CfE428DRAFT_3384	6.157e-132	422.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
ZZS2_k127_4736921_27	583355.Caka_1328	2.525e-42	161.0	COG0262@1|root,COG0262@2|Bacteria,46X6E@74201|Verrucomicrobia,3K9WI@414999|Opitutae	414999|Opitutae	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
ZZS2_k127_4736921_10	1131269.AQVV01000004_gene576	2.58e-130	449.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
ZZS2_k127_4736921_5	1403819.BATR01000181_gene6201	8.502e-152	494.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_4736921_30	398512.JQKC01000010_gene155	1.699e-40	172.0	COG2866@1|root,COG3942@1|root,COG5563@1|root,COG2866@2|Bacteria,COG3942@2|Bacteria,COG5563@2|Bacteria,1V9CS@1239|Firmicutes	1239|Firmicutes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_35	1122194.AUHU01000002_gene2690	3.554e-17	96.0	COG0810@1|root,COG3266@1|root,COG3291@1|root,COG0810@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1T46G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	REJ
ZZS2_k127_4736921_37	330214.NIDE1696	1.882e-06	59.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS2_k127_4736921_15	243231.GSU3357	3.819e-89	327.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
ZZS2_k127_4736921_12	497964.CfE428DRAFT_1688	2.824e-112	385.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
ZZS2_k127_4736921_11	113395.AXAI01000010_gene2102	2.891e-122	402.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,3JRYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	MA20_20675	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ZZS2_k127_4736921_13	1487921.DP68_05890	1.07e-97	329.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ZZS2_k127_4736921_9	497964.CfE428DRAFT_6359	9.616e-132	432.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_4736921_20	497964.CfE428DRAFT_2347	1.444e-71	254.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
ZZS2_k127_4736921_25	497964.CfE428DRAFT_2346	1.616e-55	205.0	COG3694@1|root,COG3694@2|Bacteria,46VPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
ZZS2_k127_4736921_6	497964.CfE428DRAFT_3852	1.396e-144	469.0	28J2H@1|root,2Z90R@2|Bacteria,46U80@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_31	1396418.BATQ01000044_gene6444	3.408e-40	152.0	COG0607@1|root,COG0607@2|Bacteria,46VNB@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_4736921_34	497964.CfE428DRAFT_4502	5.346e-20	95.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_4736921_2	452637.Oter_3559	2.94e-177	569.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
ZZS2_k127_4736921_4	497964.CfE428DRAFT_1577	3.075e-155	501.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
ZZS2_k127_4736921_36	349741.Amuc_0147	8.668e-14	81.0	COG2143@1|root,COG2143@2|Bacteria,46Z6E@74201|Verrucomicrobia,2IW7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
ZZS2_k127_4736921_24	349741.Amuc_0078	2.517e-60	222.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_4736921_28	497964.CfE428DRAFT_0420	9.653e-42	156.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_38	1408813.AYMG01000034_gene4482	5.952e-06	54.0	COG4914@1|root,COG4914@2|Bacteria,4NTQ4@976|Bacteroidetes,1ITBS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_0	1123242.JH636435_gene1584	1.355e-230	730.0	COG1595@1|root,COG1595@2|Bacteria,2J18F@203682|Planctomycetes	203682|Planctomycetes	K	GxGYxY sequence motif in domain of unknown function N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,GxGYxYP_C,GxGYxYP_N
ZZS2_k127_4736921_40	643867.Ftrac_3655	2.449e-05	54.0	COG2032@1|root,COG2032@2|Bacteria	2|Bacteria	P	superoxide dismutase activity	sodC	-	1.15.1.1	ko:K02674,ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	-	-	-	Sod_Cu
ZZS2_k127_4736921_29	395961.Cyan7425_1931	1.105e-40	155.0	2E79R@1|root,331TA@2|Bacteria,1GASE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_1	395961.Cyan7425_1930	2.947e-201	657.0	COG1413@1|root,COG1413@2|Bacteria,1G1H5@1117|Cyanobacteria,3KKAR@43988|Cyanothece	1117|Cyanobacteria	C	Domain of unknown function (DUF4132)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132
ZZS2_k127_4736921_33	756272.Plabr_0696	2.591e-25	107.0	COG1413@1|root,COG1413@2|Bacteria,2J0DE@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4132)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132
ZZS2_k127_4736921_17	1906.SFRA_16360	5.556e-80	285.0	COG5297@1|root,COG5297@2|Bacteria,2IF5E@201174|Actinobacteria	201174|Actinobacteria	G	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH
ZZS2_k127_4736921_22	1396418.BATQ01000054_gene27	3.712e-67	233.0	COG3428@1|root,COG3428@2|Bacteria,46W8U@74201|Verrucomicrobia,2IW78@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
ZZS2_k127_4736921_3	344747.PM8797T_18876	2.47e-163	540.0	COG3119@1|root,COG3119@2|Bacteria,2J2DZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
ZZS2_k127_4736921_14	756272.Plabr_3175	3.781e-94	336.0	28ND0@1|root,2ZBFU@2|Bacteria,2J2X6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_19	1396141.BATP01000025_gene980	2.839e-73	253.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_4736921_23	1396141.BATP01000025_gene978	6.847e-64	250.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_4736921_21	1210884.HG799465_gene11380	1.003e-70	274.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_4736921_39	357808.RoseRS_1702	1.045e-05	60.0	COG3291@1|root,COG4655@1|root,COG3291@2|Bacteria,COG4655@2|Bacteria,2G94E@200795|Chloroflexi	200795|Chloroflexi	U	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4736921_16	1123326.JFBL01000017_gene2279	2.003e-88	299.0	COG3193@1|root,COG3193@2|Bacteria,1R215@1224|Proteobacteria	1224|Proteobacteria	S	protein possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
ZZS2_k127_4736921_7	1396141.BATP01000057_gene3000	1.403e-140	477.0	COG1680@1|root,COG1680@2|Bacteria,46X3V@74201|Verrucomicrobia,2IW74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_4736921_26	330214.NIDE1073	2.966e-48	173.0	COG3813@1|root,COG3813@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	MA20_39405	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
ZZS2_k127_4736921_32	1396418.BATQ01000092_gene5860	1.879e-36	146.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
ZZS2_k127_4736921_18	760192.Halhy_2265	1.912e-74	267.0	COG2319@1|root,COG2319@2|Bacteria,4NKC3@976|Bacteroidetes,1J18Y@117747|Sphingobacteriia	976|Bacteroidetes	C	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
ZZS2_k127_474616_12	1218075.BAYA01000009_gene2885	0.0006291	42.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,1K1R9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS2_k127_474616_8	497964.CfE428DRAFT_0169	4.314e-42	162.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
ZZS2_k127_474616_11	62928.azo2583	2.133e-13	76.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,2KXEX@206389|Rhodocyclales	206389|Rhodocyclales	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
ZZS2_k127_474616_4	1396141.BATP01000023_gene745	8.133e-92	312.0	COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,2IU31@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
ZZS2_k127_474616_1	1396141.BATP01000006_gene5499	3.152e-128	417.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,2IU0V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACCA
ZZS2_k127_474616_3	497964.CfE428DRAFT_3334	2.901e-113	379.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_474616_2	883.DvMF_1002	3.7e-127	427.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MA1I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
ZZS2_k127_474616_6	497964.CfE428DRAFT_4524	2.956e-54	194.0	COG0454@1|root,COG0456@2|Bacteria,46VJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
ZZS2_k127_474616_0	1123242.JH636434_gene3671	3.059e-186	594.0	COG2133@1|root,COG2133@2|Bacteria,2IXUJ@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_474616_7	1267535.KB906767_gene3433	5.013e-49	184.0	COG1595@1|root,COG1595@2|Bacteria,3Y8YQ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_474616_10	278957.ABEA03000157_gene616	1.753e-15	87.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia,3K9N5@414999|Opitutae	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_474616_9	1283283.ATXA01000013_gene3483	8.726e-19	101.0	COG0737@1|root,COG3204@1|root,COG3401@1|root,COG3540@1|root,COG0737@2|Bacteria,COG3204@2|Bacteria,COG3401@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1,3.1.3.6,3.1.4.16	ko:K01113,ko:K01119	ko00230,ko00240,ko00790,ko01100,ko02020,map00230,map00240,map00790,map01100,map02020	M00126	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R04620,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Big_4,F5_F8_type_C,LTD,Laminin_G_3,Metallophos,PhoD,SLH,SdiA-regulated
ZZS2_k127_474616_5	1123242.JH636435_gene2487	5.153e-76	276.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_4753_6	756272.Plabr_4306	2.803e-90	323.0	COG0515@1|root,COG2202@1|root,COG3829@1|root,COG0515@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	EAL,GAF,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_4753_7	1397284.AYMN01000039_gene1398	2.651e-37	153.0	COG3254@1|root,COG3254@2|Bacteria,1RGYV@1224|Proteobacteria,1S6AI@1236|Gammaproteobacteria,403Q8@613|Serratia	1236|Gammaproteobacteria	G	Involved in the anomeric conversion of L-rhamnose	rhaM	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
ZZS2_k127_4753_3	497964.CfE428DRAFT_5044	1.644e-127	414.0	COG2513@1|root,COG2513@2|Bacteria	2|Bacteria	G	methylisocitrate lyase activity	prpB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407	PEP_mutase
ZZS2_k127_4753_1	497964.CfE428DRAFT_5045	4.319e-172	546.0	COG0372@1|root,COG0372@2|Bacteria,46SBV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ZZS2_k127_4753_4	1123278.KB893561_gene3155	7.795e-101	344.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_4753_2	497964.CfE428DRAFT_6587	1.126e-163	524.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_4753_10	794903.OPIT5_19315	5.738e-23	104.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
ZZS2_k127_4753_8	794903.OPIT5_19320	3.689e-29	121.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
ZZS2_k127_4753_5	497964.CfE428DRAFT_6588	8.244e-97	323.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
ZZS2_k127_4753_0	497964.CfE428DRAFT_5043	6.807e-189	601.0	COG2079@1|root,COG2079@2|Bacteria,46VQ9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MmgE/PrpD family	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
ZZS2_k127_4753_12	7668.SPU_009732-tr	1.192e-08	64.0	COG1078@1|root,KOG2681@2759|Eukaryota,38FGQ@33154|Opisthokonta,3BH1G@33208|Metazoa,3CXN4@33213|Bilateria	33208|Metazoa	S	SAM domain and HD domain, 1	SAMHD1	GO:0000166,GO:0002252,GO:0002376,GO:0002682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008270,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0010033,GO:0016020,GO:0016043,GO:0016070,GO:0016787,GO:0016788,GO:0016793,GO:0017076,GO:0018130,GO:0019001,GO:0019221,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0023052,GO:0031347,GO:0031974,GO:0031981,GO:0032552,GO:0032554,GO:0032560,GO:0032567,GO:0034097,GO:0034340,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042221,GO:0042578,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045087,GO:0045088,GO:0046060,GO:0046061,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0048583,GO:0050776,GO:0050789,GO:0050794,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055086,GO:0060337,GO:0065003,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071357,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0080134,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0097367,GO:0098542,GO:0140098,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K12830	ko03040,map03040	M00352	-	-	ko00000,ko00001,ko00002,ko03021,ko03036,ko03041	-	-	-	HD,SAM_1,SAM_2
ZZS2_k127_4753_13	292459.STH1116	0.0004391	44.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,24DGJ@186801|Clostridia	186801|Clostridia	S	SMART metal-dependent phosphohydrolase, HD	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
ZZS2_k127_4753_11	686340.Metal_0736	2.905e-20	93.0	COG1106@1|root,COG1106@2|Bacteria,1R43N@1224|Proteobacteria	1224|Proteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
ZZS2_k127_4767505_1	404589.Anae109_0983	8.922e-172	544.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
ZZS2_k127_4767505_0	240016.ABIZ01000001_gene2053	4.779e-281	873.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
ZZS2_k127_4767505_11	344747.PM8797T_25446	8.214e-13	71.0	COG0492@1|root,COG0492@2|Bacteria,2J52X@203682|Planctomycetes	203682|Planctomycetes	O	secreted protein-putative xanthan lyase related	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
ZZS2_k127_4767505_7	497964.CfE428DRAFT_1521	6.259e-62	222.0	COG0461@1|root,COG0461@2|Bacteria,46SZV@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
ZZS2_k127_4767505_6	794903.OPIT5_01880	1.519e-65	232.0	COG0725@1|root,COG0725@2|Bacteria,46V5J@74201|Verrucomicrobia,3K8A9@414999|Opitutae	414999|Opitutae	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
ZZS2_k127_4767505_14	84531.JMTZ01000062_gene1983	0.0002226	53.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria	1224|Proteobacteria	MU	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin-like,He_PIG
ZZS2_k127_4767505_15	215803.DB30_0610	0.0003888	53.0	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
ZZS2_k127_4767505_3	497964.CfE428DRAFT_4351	1.795e-102	342.0	COG0583@1|root,COG0583@2|Bacteria,46TTX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_4767505_9	710111.FraQA3DRAFT_2822	8.855e-23	103.0	COG1942@1|root,COG1942@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
ZZS2_k127_4767505_10	1267534.KB906754_gene3268	7.219e-20	105.0	2DP2V@1|root,330AH@2|Bacteria,3Y5MP@57723|Acidobacteria,2JJZ7@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
ZZS2_k127_4767505_4	338969.Rfer_0647	7.322e-77	282.0	COG2133@1|root,COG2133@2|Bacteria,1QZ0Q@1224|Proteobacteria,2WHH9@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
ZZS2_k127_4767505_12	640081.Dsui_3350	1.208e-11	78.0	2ED9V@1|root,33769@2|Bacteria,1N87Z@1224|Proteobacteria,2W3PP@28216|Betaproteobacteria,2KZ35@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
ZZS2_k127_4767505_8	452637.Oter_3779	2.211e-31	134.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia,3K9NK@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4767505_13	9940.ENSOARP00000006517	1.829e-08	67.0	COG4886@1|root,KOG0619@2759|Eukaryota,38CAQ@33154|Opisthokonta,3BIGC@33208|Metazoa,3CZHW@33213|Bilateria,481FX@7711|Chordata,48V0V@7742|Vertebrata,3JD9H@40674|Mammalia,4J9T9@91561|Cetartiodactyla	33208|Metazoa	T	Leucine Rich Repeat	PODN	GO:0001932,GO:0001933,GO:0003674,GO:0004857,GO:0004860,GO:0005488,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006469,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008285,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0019207,GO:0019210,GO:0019220,GO:0019221,GO:0019222,GO:0019887,GO:0023051,GO:0023052,GO:0023057,GO:0030234,GO:0030334,GO:0030336,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032879,GO:0033673,GO:0034097,GO:0040012,GO:0040013,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0043086,GO:0043549,GO:0044092,GO:0044421,GO:0044424,GO:0044464,GO:0044877,GO:0045859,GO:0045936,GO:0046425,GO:0046426,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051270,GO:0051271,GO:0051338,GO:0051348,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071310,GO:0071345,GO:0080090,GO:0098772,GO:1902531,GO:1902532,GO:1904892,GO:1904893,GO:2000145,GO:2000146	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_5,LRR_8
ZZS2_k127_4767505_2	1396141.BATP01000030_gene3706	2.128e-109	383.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS2_k127_4767505_5	1396141.BATP01000030_gene3705	4.621e-74	254.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_4777150_5	1403819.BATR01000104_gene3513	6.48e-99	338.0	COG1250@1|root,COG1250@2|Bacteria,46TNQ@74201|Verrucomicrobia,2IWBJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4777150_3	344747.PM8797T_24141	2.499e-134	442.0	COG1520@1|root,COG1520@2|Bacteria,2IYK2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_4777150_2	497964.CfE428DRAFT_5136	4.224e-202	632.0	COG0174@1|root,COG0174@2|Bacteria,46S5C@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Gln-synt_C,Gln-synt_N
ZZS2_k127_4777150_7	497964.CfE428DRAFT_5135	1.644e-46	174.0	COG3642@1|root,COG3642@2|Bacteria,46ST7@74201|Verrucomicrobia	74201|Verrucomicrobia	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4777150_4	497964.CfE428DRAFT_5134	3.35e-114	374.0	COG0631@1|root,COG0631@2|Bacteria,46S8Z@74201|Verrucomicrobia	74201|Verrucomicrobia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS2_k127_4777150_0	452637.Oter_2476	5.676e-228	717.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,3K7NK@414999|Opitutae	414999|Opitutae	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
ZZS2_k127_4777150_6	497964.CfE428DRAFT_5003	4.606e-53	188.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
ZZS2_k127_4777150_1	497964.CfE428DRAFT_0232	7.754e-212	674.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4777150_8	1242864.D187_001629	1.617e-35	143.0	COG3832@1|root,COG3832@2|Bacteria,1PQB7@1224|Proteobacteria,43E0W@68525|delta/epsilon subdivisions,2WZDG@28221|Deltaproteobacteria,2Z1WA@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
ZZS2_k127_4809308_2	1396141.BATP01000025_gene980	4.822e-68	239.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_4809308_1	452637.Oter_0462	5.81e-78	270.0	COG1639@1|root,COG1639@2|Bacteria,46WBU@74201|Verrucomicrobia,3K7UG@414999|Opitutae	414999|Opitutae	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
ZZS2_k127_4809308_4	452637.Oter_0465	7.054e-42	173.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46VEZ@74201|Verrucomicrobia,3K7DT@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
ZZS2_k127_4809308_5	497964.CfE428DRAFT_2157	4.519e-29	124.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
ZZS2_k127_4809308_3	395493.BegalDRAFT_1191	1.241e-52	191.0	2D596@1|root,32TII@2|Bacteria,1N3RK@1224|Proteobacteria,1S867@1236|Gammaproteobacteria,460YQ@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4809308_0	1125863.JAFN01000001_gene1747	3.905e-104	371.0	28JTH@1|root,2Z9IS@2|Bacteria,1N22P@1224|Proteobacteria,42YBU@68525|delta/epsilon subdivisions,2WTWU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4823724_1	1278073.MYSTI_07731	4.73e-212	683.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS2_k127_4823724_4	573061.Clocel_1966	1.838e-39	173.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_4823724_0	1396141.BATP01000034_gene4198	3.466e-247	848.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_4823724_6	1396141.BATP01000051_gene3312	2.172e-10	76.0	COG3209@1|root,COG3266@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,MucBP,Phospholip_A2_3,YSIRK_signal
ZZS2_k127_4823724_2	1232437.KL661985_gene3563	8.133e-119	399.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,42RYP@68525|delta/epsilon subdivisions,2WNDE@28221|Deltaproteobacteria,2MK5X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,3.5.1.99	ko:K01426,ko:K19176	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
ZZS2_k127_4823724_3	211165.AJLN01000145_gene1322	3.208e-108	366.0	COG2730@1|root,COG2730@2|Bacteria,1G3EZ@1117|Cyanobacteria	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
ZZS2_k127_4823724_5	246196.MSMEI_5805	1.569e-32	130.0	2DQMZ@1|root,337PX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4836893_9	497964.CfE428DRAFT_0022	7.285e-108	353.0	COG0217@1|root,COG0217@2|Bacteria,46SMV@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
ZZS2_k127_4836893_17	278957.ABEA03000203_gene2703	1.128e-39	152.0	COG4747@1|root,COG4747@2|Bacteria,46SXP@74201|Verrucomicrobia,3K816@414999|Opitutae	414999|Opitutae	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4836893_5	880073.Calab_3201	2.172e-137	451.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
ZZS2_k127_4836893_1	344747.PM8797T_00507	1.823e-218	696.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
ZZS2_k127_4836893_8	497964.CfE428DRAFT_5447	3.239e-108	364.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
ZZS2_k127_4836893_14	313612.L8106_25992	5.716e-52	196.0	COG3971@1|root,COG3971@2|Bacteria,1G0T7@1117|Cyanobacteria,1HAQP@1150|Oscillatoriales	1117|Cyanobacteria	Q	2-keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4836893_4	1121430.JMLG01000023_gene1442	1.337e-149	501.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia,26769@186807|Peptococcaceae	186801|Clostridia	P	Similarity to COG0471 Di- and tricarboxylate transporters(Evalue	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
ZZS2_k127_4836893_10	497964.CfE428DRAFT_0539	8.941e-93	310.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
ZZS2_k127_4836893_18	478741.JAFS01000001_gene1060	2.278e-31	127.0	COG2026@1|root,COG2026@2|Bacteria,46Z14@74201|Verrucomicrobia,37H0T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4836893_24	1121920.AUAU01000001_gene2235	9.638e-06	51.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
ZZS2_k127_4836893_0	1396141.BATP01000056_gene3277	0.0	1520.0	COG3209@1|root,COG3209@2|Bacteria,46TP7@74201|Verrucomicrobia,2IVDA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
ZZS2_k127_4836893_16	1396141.BATP01000056_gene3278	2.601e-46	193.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
ZZS2_k127_4836893_22	1123020.AUIE01000001_gene2404	1.438e-10	76.0	COG2373@1|root,COG2931@1|root,COG2982@1|root,COG3210@1|root,COG4932@1|root,COG5184@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria,1YFJH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
ZZS2_k127_4836893_19	1123508.JH636441_gene3386	9.271e-31	143.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4347,MAM,Trypsin_2
ZZS2_k127_4836893_20	1122132.AQYH01000007_gene2185	2.727e-24	105.0	2ESJH@1|root,33K45@2|Bacteria,1PXP4@1224|Proteobacteria,2V0GG@28211|Alphaproteobacteria,4BGM9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
ZZS2_k127_4836893_7	1403819.BATR01000168_gene5780	9.2e-116	380.0	COG1082@1|root,COG1082@2|Bacteria,46UG0@74201|Verrucomicrobia,2IUX7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_4836893_2	344747.PM8797T_20483	6.225e-181	599.0	COG2133@1|root,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_4836893_12	1123508.JH636443_gene4582	7.228e-63	227.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_4836893_6	886293.Sinac_2616	5.053e-134	434.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_4836893_23	1521187.JPIM01000176_gene934	1.134e-09	72.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4836893_15	1121403.AUCV01000002_gene446	4.9e-50	192.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,42P50@68525|delta/epsilon subdivisions,2WKU5@28221|Deltaproteobacteria,2MMX2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
ZZS2_k127_4836893_21	926561.KB900623_gene950	2.598e-11	76.0	COG1178@1|root,COG1178@2|Bacteria,1VJSK@1239|Firmicutes,24SSE@186801|Clostridia	186801|Clostridia	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	-
ZZS2_k127_4836893_11	575540.Isop_2739	1.001e-67	246.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
ZZS2_k127_4836893_3	344747.PM8797T_27784	4.754e-166	545.0	COG2010@1|root,COG2010@2|Bacteria,2J2QT@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_4887690_12	861299.J421_5950	4.389e-05	46.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH,HEAT_2,Mo-co_dimer,Oxidored_molyb
ZZS2_k127_4887690_2	886293.Sinac_4671	1.56e-161	516.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4887690_4	1408254.T458_26445	2.082e-127	422.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
ZZS2_k127_4887690_6	926556.Echvi_0208	2.358e-67	237.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS2_k127_4887690_1	1403819.BATR01000033_gene1105	2.818e-178	571.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia,2IWJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_4887690_5	497964.CfE428DRAFT_0981	1.095e-98	332.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
ZZS2_k127_4887690_0	1396418.BATQ01000004_gene1358	4.093e-220	709.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,2ITZN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	E1-E2 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
ZZS2_k127_4887690_3	1123242.JH636434_gene3999	2.471e-151	498.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_4887690_8	244582.JQAK01000002_gene474	4.076e-11	68.0	COG3344@1|root,COG3344@2|Bacteria,1NB7T@1224|Proteobacteria,2UU48@28211|Alphaproteobacteria,47GDS@766|Rickettsiales	766|Rickettsiales	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4887690_7	378806.STAUR_3100	6.265e-40	157.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YTTS@29|Myxococcales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
ZZS2_k127_4887690_9	370438.PTH_2688	2.272e-09	71.0	COG0491@1|root,COG0491@2|Bacteria,1UZUA@1239|Firmicutes,24CIA@186801|Clostridia,26369@186807|Peptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS2_k127_4887690_10	552398.HMPREF0866_01255	4.386e-07	55.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WGHH@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_5,Cu_amine_oxidN1,PDZ_2,Peptidase_S41,SH3_3,SLH
ZZS2_k127_4898749_5	404589.Anae109_2675	3.156e-32	136.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
ZZS2_k127_4898749_4	266117.Rxyl_0053	4.12e-64	230.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CQA7@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
ZZS2_k127_4898749_1	639282.DEFDS_0119	3.285e-98	326.0	COG0528@1|root,COG0528@2|Bacteria,2GEZE@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ZZS2_k127_4898749_2	497964.CfE428DRAFT_2907	2.837e-96	322.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
ZZS2_k127_4898749_3	639282.DEFDS_0051	2.614e-78	271.0	COG0052@1|root,COG0052@2|Bacteria,2GEX6@200930|Deferribacteres	200930|Deferribacteres	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
ZZS2_k127_4898749_0	497964.CfE428DRAFT_0324	0.0	1250.0	COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS2_k127_4898749_6	1121930.AQXG01000002_gene2124	1.579e-23	117.0	COG1404@1|root,COG1404@2|Bacteria,4PPN8@976|Bacteroidetes,1J10J@117747|Sphingobacteriia	2|Bacteria	O	SusE outer membrane protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF1573,LTD,Laminin_G_3,SusE
ZZS2_k127_4899759_7	1396418.BATQ01000050_gene303	1.387e-28	120.0	COG0782@1|root,COG0782@2|Bacteria,46T65@74201|Verrucomicrobia,2IUVV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4899759_9	448385.sce9166	1.023e-13	86.0	COG1414@1|root,COG1414@2|Bacteria,1Q48S@1224|Proteobacteria,42YKZ@68525|delta/epsilon subdivisions,2WUID@28221|Deltaproteobacteria,2YW86@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_4899759_10	316067.Geob_0740	1.584e-11	69.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria	1224|Proteobacteria	S	SMART Transport-associated and nodulation region	osmY_2	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
ZZS2_k127_4899759_2	1396418.BATQ01000149_gene2216	1.114e-110	372.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
ZZS2_k127_4899759_3	448385.sce5500	2.832e-78	294.0	2DB8Y@1|root,2Z7TF@2|Bacteria,1MW4C@1224|Proteobacteria,43B9R@68525|delta/epsilon subdivisions,2X6NW@28221|Deltaproteobacteria,2YZWI@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
ZZS2_k127_4899759_0	99598.Cal7507_3912	5.528e-158	534.0	COG0664@1|root,COG0845@1|root,COG1252@1|root,COG0664@2|Bacteria,COG0845@2|Bacteria,COG1252@2|Bacteria,1G43N@1117|Cyanobacteria,1HS49@1161|Nostocales	1117|Cyanobacteria	CMT	Cyclic nucleotide modulated ABC exporter membrane fusion protein, DevB family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,Pyr_redox_2,cNMP_binding
ZZS2_k127_4899759_1	661478.OP10G_3688	1.293e-138	453.0	arCOG06766@1|root,2Z87F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4899759_5	1210884.HG799465_gene11380	6.177e-69	266.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_4899759_4	1123278.KB893533_gene138	5.179e-75	272.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47Q9Y@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	xynT	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
ZZS2_k127_4899759_6	502025.Hoch_1135	1.144e-57	225.0	COG5492@1|root,COG5492@2|Bacteria,1NRJ3@1224|Proteobacteria,43CYM@68525|delta/epsilon subdivisions,2X86S@28221|Deltaproteobacteria,2Z3MB@29|Myxococcales	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,LRR_5,Metallophos,NAGPA,fn3
ZZS2_k127_4905561_1	794903.OPIT5_24500	1.702e-94	319.0	COG0657@1|root,COG0657@2|Bacteria,46VDF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_4905561_2	1122925.KB895378_gene2567	1.278e-23	117.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_4905561_0	398767.Glov_2241	6.994e-124	409.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2WVM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glutathionylspermidine synthase preATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
ZZS2_k127_4905561_4	388739.RSK20926_10554	0.0007105	51.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2U2BP@28211|Alphaproteobacteria,2P435@2433|Roseobacter	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
ZZS2_k127_4913329_4	696747.NIES39_C05180	2.34e-58	223.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
ZZS2_k127_4913329_6	399742.Ent638_0550	2.572e-10	68.0	COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,1RNSV@1236|Gammaproteobacteria,3X02B@547|Enterobacter	1236|Gammaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
ZZS2_k127_4913329_3	1122925.KB895383_gene3502	1.725e-68	255.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PKD
ZZS2_k127_4913329_0	497964.CfE428DRAFT_6590	1.127e-272	849.0	COG1884@1|root,COG1884@2|Bacteria	2|Bacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
ZZS2_k127_4913329_1	497964.CfE428DRAFT_6589	9.62e-128	420.0	COG1703@1|root,COG2185@1|root,COG1703@2|Bacteria,COG2185@2|Bacteria,46TIM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding
ZZS2_k127_4913329_2	1379698.RBG1_1C00001G0540	8.916e-78	286.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SBBP
ZZS2_k127_4913329_5	794903.OPIT5_22660	7.909e-15	89.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4913329_7	483216.BACEGG_00986	8.351e-06	59.0	COG4447@1|root,COG4447@2|Bacteria,4NX71@976|Bacteroidetes,2FXP6@200643|Bacteroidia,4ATV2@815|Bacteroidaceae	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4920026_6	1123401.JHYQ01000014_gene885	5.571e-16	81.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
ZZS2_k127_4920026_2	497964.CfE428DRAFT_6460	4.313e-226	707.0	COG4102@1|root,COG4102@2|Bacteria,46UVF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_4920026_1	1403819.BATR01000053_gene1632	4.799e-308	967.0	COG5492@1|root,COG5492@2|Bacteria,46TE9@74201|Verrucomicrobia	74201|Verrucomicrobia	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt2,PSD1
ZZS2_k127_4920026_0	99598.Cal7507_1620	0.0	1147.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1HM59@1161|Nostocales	1117|Cyanobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
ZZS2_k127_4920026_5	1227487.C474_17739	5.532e-50	191.0	COG0451@1|root,arCOG03095@2157|Archaea,2XTPI@28890|Euryarchaeota,23STT@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
ZZS2_k127_4920026_4	1144275.COCOR_00131	1.667e-77	280.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE3,DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
ZZS2_k127_4920026_3	661478.OP10G_1948	3.336e-94	335.0	COG0339@1|root,COG0339@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	prlC	-	3.4.24.15,3.4.24.70	ko:K01392,ko:K01414	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
ZZS2_k127_4961065_0	1396141.BATP01000003_gene4934	2.893e-114	413.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_4961065_2	1049564.TevJSym_az00010	1.593e-28	135.0	COG2312@1|root,COG3386@1|root,COG3540@1|root,COG2312@2|Bacteria,COG3386@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Erythro_esteras,LTD
ZZS2_k127_4961065_4	8049.ENSGMOP00000000484	0.0001611	55.0	KOG1094@1|root,KOG1094@2759|Eukaryota,3AJH0@33154|Opisthokonta,3BYZX@33208|Metazoa,3DE8H@33213|Bilateria,48IVW@7711|Chordata,49FQN@7742|Vertebrata,4A6KH@7898|Actinopterygii	33208|Metazoa	T	Discoidin domain receptor family, member 2, like	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4961065_3	1396141.BATP01000051_gene3310	1.332e-11	75.0	COG3209@1|root,COG3266@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,MucBP,Phospholip_A2_3,YSIRK_signal
ZZS2_k127_4961065_1	1396141.BATP01000022_gene335	3.443e-54	212.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5002529_8	1123070.KB899258_gene1877	2.545e-81	286.0	COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
ZZS2_k127_5002529_5	240016.ABIZ01000001_gene5351	1.091e-113	380.0	COG0438@1|root,COG0438@2|Bacteria,46VHB@74201|Verrucomicrobia,2IVB9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5002529_22	903818.KI912268_gene1516	4.15e-19	100.0	COG4191@1|root,COG4191@2|Bacteria,3Y3MW@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
ZZS2_k127_5002529_14	56780.SYN_01954	2.266e-66	241.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
ZZS2_k127_5002529_11	56780.SYN_01953	5.1e-74	255.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_5002529_6	240016.ABIZ01000001_gene5349	2.224e-103	372.0	COG1596@1|root,COG3206@1|root,COG1596@2|Bacteria,COG3206@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
ZZS2_k127_5002529_9	240016.ABIZ01000001_gene5347	5.674e-76	268.0	COG1596@1|root,COG1596@2|Bacteria,46XCW@74201|Verrucomicrobia,2IVGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
ZZS2_k127_5002529_7	1122176.KB903598_gene4712	7.258e-86	325.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
ZZS2_k127_5002529_23	105559.Nwat_2855	5.349e-16	94.0	COG1409@1|root,COG3291@1|root,COG3509@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1QW3S@1224|Proteobacteria	1224|Proteobacteria	Q	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5002529_21	575540.Isop_1705	3.092e-29	138.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_5002529_1	1123070.KB899258_gene1955	1.864e-238	807.0	COG4409@1|root,COG4409@2|Bacteria,46WMH@74201|Verrucomicrobia,2IWFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5002529_19	398512.JQKC01000009_gene378	1.955e-43	185.0	COG0845@1|root,COG1075@1|root,COG0845@2|Bacteria,COG1075@2|Bacteria,1V909@1239|Firmicutes,24M6V@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LCAT,VWA,VWA_2
ZZS2_k127_5002529_10	240016.ABIZ01000001_gene4666	2.884e-75	261.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,2IUI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_5002529_12	1403819.BATR01000181_gene6248	5.027e-73	266.0	COG4585@1|root,COG4585@2|Bacteria,46TVJ@74201|Verrucomicrobia,2IV6E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
ZZS2_k127_5002529_16	667632.KB890164_gene2209	8.982e-49	181.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria	1224|Proteobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K05518	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
ZZS2_k127_5002529_18	1380391.JIAS01000015_gene77	3.093e-44	165.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,2UGY5@28211|Alphaproteobacteria,2JU93@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
ZZS2_k127_5002529_17	1380391.JIAS01000015_gene76	2.502e-46	169.0	COG1366@1|root,COG1366@2|Bacteria,1RJM8@1224|Proteobacteria,2UAWA@28211|Alphaproteobacteria,2JU7M@204441|Rhodospirillales	204441|Rhodospirillales	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
ZZS2_k127_5002529_3	469383.Cwoe_3437	3.652e-138	446.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
ZZS2_k127_5002529_0	1123070.KB899258_gene1955	2.663e-248	794.0	COG4409@1|root,COG4409@2|Bacteria,46WMH@74201|Verrucomicrobia,2IWFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5002529_4	240016.ABIZ01000001_gene5361	3.241e-134	439.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5002529_20	765952.PUV_07450	2.053e-42	167.0	COG0572@1|root,COG0572@2|Bacteria,2JG18@204428|Chlamydiae	204428|Chlamydiae	F	nucleoside kinase activity	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
ZZS2_k127_5002529_13	382464.ABSI01000017_gene36	1.573e-71	248.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS2_k127_5002529_15	240016.ABIZ01000001_gene5363	2.282e-53	206.0	COG1208@1|root,COG1208@2|Bacteria,46ZHB@74201|Verrucomicrobia,2IUTI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5002529_25	91464.S7335_3809	2.263e-05	52.0	COG1366@1|root,COG1366@2|Bacteria,1GEYS@1117|Cyanobacteria,1H23G@1129|Synechococcus	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
ZZS2_k127_5002529_2	240016.ABIZ01000001_gene5365	8.533e-160	513.0	COG1524@1|root,COG1524@2|Bacteria,46XAN@74201|Verrucomicrobia,2IV7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS2_k127_5029568_0	794903.OPIT5_30200	2.4e-237	747.0	COG0664@1|root,COG4651@1|root,COG0664@2|Bacteria,COG4651@2|Bacteria	2|Bacteria	P	solute:proton antiporter activity	-	-	-	ko:K03455,ko:K07058	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N,Virul_fac_BrkB,cNMP_binding
ZZS2_k127_5029568_1	118173.KB235914_gene3829	2.39e-117	395.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_504142_14	1297617.JPJD01000047_gene1362	2.106e-51	188.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
ZZS2_k127_504142_2	1396418.BATQ01000155_gene2495	8.909e-166	531.0	COG1520@1|root,COG1520@2|Bacteria,46TM3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_504142_1	886293.Sinac_6095	1.134e-247	788.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
ZZS2_k127_504142_7	1123508.JH636441_gene3462	7.572e-102	346.0	COG1680@1|root,COG1680@2|Bacteria,2IY88@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Beta-lactamase
ZZS2_k127_504142_3	575540.Isop_2634	8.931e-162	522.0	COG1850@1|root,COG1850@2|Bacteria	2|Bacteria	G	ribulose-bisphosphate carboxylase activity	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
ZZS2_k127_504142_9	1242864.D187_009734	1.613e-77	269.0	COG0504@1|root,COG0504@2|Bacteria,1QBV2@1224|Proteobacteria,43A2I@68525|delta/epsilon subdivisions,2X20W@28221|Deltaproteobacteria,2YZU3@29|Myxococcales	28221|Deltaproteobacteria	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
ZZS2_k127_504142_5	1089551.KE386572_gene2869	1.553e-130	432.0	COG0673@1|root,COG0673@2|Bacteria,1MWNK@1224|Proteobacteria,2U4BM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_504142_12	344747.PM8797T_15326	3.617e-66	236.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IZ2K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_504142_6	278963.ATWD01000002_gene473	5.71e-122	405.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
ZZS2_k127_504142_11	1410620.SHLA_2c001030	4.674e-74	258.0	COG1082@1|root,COG1082@2|Bacteria,1N1AK@1224|Proteobacteria,2U3TU@28211|Alphaproteobacteria,4BB6Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_504142_10	886293.Sinac_2235	6.969e-77	270.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS2_k127_504142_16	1123508.JH636444_gene5259	2.135e-29	136.0	COG0652@1|root,COG3170@1|root,COG3210@1|root,COG4932@1|root,COG0652@2|Bacteria,COG3170@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,2J03X@203682|Planctomycetes	203682|Planctomycetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase,SdrD_B
ZZS2_k127_504142_19	1396141.BATP01000007_gene5656	6.869e-09	71.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_504142_15	573061.Clocel_1966	1.558e-31	146.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_504142_17	313606.M23134_01193	1.031e-22	117.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
ZZS2_k127_504142_20	1123037.AUDE01000006_gene1094	4.688e-08	68.0	COG1404@1|root,COG2273@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2273@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
ZZS2_k127_504142_21	1410628.JNKS01000016_gene69	1.49e-05	60.0	COG5337@1|root,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,27J6M@186928|unclassified Lachnospiraceae	186801|Clostridia	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
ZZS2_k127_504142_13	1396141.BATP01000034_gene4198	1.882e-64	255.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_504142_8	502025.Hoch_3453	1.663e-95	358.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_504142_4	686340.Metal_1682	1.399e-144	471.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RXW3@1236|Gammaproteobacteria,1XGS8@135618|Methylococcales	135618|Methylococcales	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
ZZS2_k127_504142_0	497964.CfE428DRAFT_6352	0.0	1215.0	COG1061@1|root,COG2852@1|root,COG4951@1|root,COG1061@2|Bacteria,COG2852@2|Bacteria,COG4951@2|Bacteria,46UU5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559,ResIII
ZZS2_k127_504142_18	1131462.DCF50_p1234	1.358e-12	82.0	COG4951@1|root,COG4951@2|Bacteria,1UIK4@1239|Firmicutes,25G0B@186801|Clostridia	186801|Clostridia	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5049693_0	452637.Oter_2196	4.901e-140	461.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_5049693_1	1396418.BATQ01000127_gene2542	3.121e-109	361.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_6,DLH,Peptidase_S9
ZZS2_k127_5060171_7	243090.RB2086	1.013e-23	105.0	COG0457@1|root,COG2755@1|root,COG0457@2|Bacteria,COG2755@2|Bacteria,2IXJ9@203682|Planctomycetes	2|Bacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_5060171_8	1396141.BATP01000020_gene2	6.469e-11	78.0	COG2755@1|root,COG3317@1|root,COG4409@1|root,COG5267@1|root,COG2755@2|Bacteria,COG3317@2|Bacteria,COG4409@2|Bacteria,COG5267@2|Bacteria,46XM5@74201|Verrucomicrobia,2IW6D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,SASA
ZZS2_k127_5060171_9	864051.BurJ1DRAFT_0895	1.563e-08	70.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
ZZS2_k127_5060171_3	1101195.Meth11DRAFT_0831	3.047e-66	261.0	COG1572@1|root,COG1858@1|root,COG3103@1|root,COG3210@1|root,COG3391@1|root,COG3979@1|root,COG5295@1|root,COG1572@2|Bacteria,COG1858@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3979@2|Bacteria,COG4991@2|Bacteria,COG5295@2|Bacteria,1MV70@1224|Proteobacteria,2VI1Z@28216|Betaproteobacteria,2KNCT@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Di-haem cytochrome c peroxidase	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
ZZS2_k127_5060171_5	926550.CLDAP_29960	2.143e-34	156.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD
ZZS2_k127_5060171_0	1396141.BATP01000030_gene3715	3.866e-210	728.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
ZZS2_k127_5060171_2	1123242.JH636436_gene726	1.823e-72	264.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_5060171_10	1132441.KI519454_gene1910	5.705e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,1W7XF@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS2_k127_5060171_6	649638.Trad_2408	2.117e-26	114.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
ZZS2_k127_5060171_1	251221.35213551	3.764e-91	313.0	COG2370@1|root,COG2370@2|Bacteria,1G65K@1117|Cyanobacteria	1117|Cyanobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
ZZS2_k127_5060171_4	448385.sce5426	1.365e-41	157.0	2DHHJ@1|root,2ZZT4@2|Bacteria,1P8VN@1224|Proteobacteria,437HA@68525|delta/epsilon subdivisions,2WYJV@28221|Deltaproteobacteria,2Z0XT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5092076_3	886293.Sinac_5714	8.693e-40	152.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYA8@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_5092076_1	452637.Oter_0012	4.394e-68	239.0	COG1704@1|root,COG1704@2|Bacteria,46V9M@74201|Verrucomicrobia,3K7DK@414999|Opitutae	2|Bacteria	S	PFAM LemA family protein	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS2_k127_5092076_2	452637.Oter_0011	9.464e-58	212.0	COG1512@1|root,COG1512@2|Bacteria,46T36@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
ZZS2_k127_5092076_4	497964.CfE428DRAFT_4724	1.665e-34	141.0	COG3762@1|root,COG3762@2|Bacteria,46T8V@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
ZZS2_k127_5092076_0	1123508.JH636442_gene4251	4.201e-126	413.0	COG4307@1|root,COG4307@2|Bacteria,2IXC4@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
ZZS2_k127_5092076_5	1396418.BATQ01000143_gene3471	2.832e-10	65.0	2EMKC@1|root,33F8T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5097290_2	1396141.BATP01000027_gene1101	0.0004133	55.0	COG2133@1|root,COG3266@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	oapA	-	2.7.7.7,3.1.26.12	ko:K02343,ko:K02451,ko:K06867,ko:K07268,ko:K08300	ko00230,ko00240,ko01100,ko03018,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03430,map03440	M00260,M00331,M00394	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02044,ko03009,ko03019,ko03032,ko03400	9.B.42	-	-	OapA,OapA_N,PA14
ZZS2_k127_5097290_1	452637.Oter_0312	2.277e-25	125.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
ZZS2_k127_5097290_0	1396141.BATP01000003_gene4934	4.829e-139	491.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_5133471_7	1449353.JQMQ01000005_gene2794	2.234e-05	54.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,2NG98@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_5133471_5	326427.Cagg_3284	4.71e-14	86.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
ZZS2_k127_5133471_3	1123278.KB893427_gene1235	1.402e-49	199.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5133471_6	98439.AJLL01000090_gene161	1.544e-08	68.0	2EE4N@1|root,337ZA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5133471_2	1123248.KB893370_gene5135	1.85e-126	414.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IX3R@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_5133471_0	344747.PM8797T_20763	8.926e-132	436.0	COG1331@1|root,COG1331@2|Bacteria,2IXCB@203682|Planctomycetes	203682|Planctomycetes	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
ZZS2_k127_5133471_1	240016.ABIZ01000001_gene824	2.225e-129	424.0	COG0859@1|root,COG0859@2|Bacteria,46TJT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Mannosyl_trans3
ZZS2_k127_5134304_4	1396418.BATQ01000110_gene4800	2.616e-11	72.0	2E4YE@1|root,32ZSA@2|Bacteria,46WYD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5134304_2	278957.ABEA03000164_gene4115	1.034e-60	216.0	COG0131@1|root,COG0131@2|Bacteria,46UDT@74201|Verrucomicrobia,3K7V8@414999|Opitutae	414999|Opitutae	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
ZZS2_k127_5134304_3	497964.CfE428DRAFT_0896	1.099e-39	154.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5134304_0	382464.ABSI01000012_gene1970	2.193e-183	594.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia,2ITMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
ZZS2_k127_5134304_1	452637.Oter_0292	3.496e-81	284.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
ZZS2_k127_5134304_5	1156937.MFUM_290012	2.554e-09	60.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
ZZS2_k127_5140474_6	1123242.JH636434_gene5230	1.145e-37	145.0	COG3882@1|root,COG3882@2|Bacteria,2J3F4@203682|Planctomycetes	203682|Planctomycetes	Q	phosphopantetheine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5140474_9	1198114.AciX9_2887	3.327e-08	58.0	COG0236@1|root,COG0236@2|Bacteria,3Y5X4@57723|Acidobacteria,2JK2V@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	-
ZZS2_k127_5140474_7	886293.Sinac_0008	2.799e-30	134.0	COG0454@1|root,COG0456@2|Bacteria,2J401@203682|Planctomycetes	203682|Planctomycetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5140474_4	1504672.669785683	6.366e-47	181.0	COG0726@1|root,COG0726@2|Bacteria,1PHXK@1224|Proteobacteria,2VVVM@28216|Betaproteobacteria,4AJ10@80864|Comamonadaceae	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ZZS2_k127_5140474_3	671143.DAMO_2354	5.023e-73	256.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
ZZS2_k127_5140474_5	497964.CfE428DRAFT_5946	4.997e-40	158.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5140474_1	243090.RB12393	7.943e-132	444.0	COG3303@1|root,COG3303@2|Bacteria,2J0SN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
ZZS2_k127_5140474_0	497964.CfE428DRAFT_2485	2.857e-185	588.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5140474_2	404380.Gbem_2394	1.051e-81	292.0	COG0784@1|root,COG2202@1|root,COG2208@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,1NC9X@1224|Proteobacteria,43C4D@68525|delta/epsilon subdivisions,2X7EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domains REC, PAS, PAS, PP2C	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_9,Response_reg,SpoIIE
ZZS2_k127_5142351_3	426355.Mrad2831_4023	1.033e-54	199.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TTNG@28211|Alphaproteobacteria,1JSF8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_43565	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_5142351_1	944480.ATUV01000001_gene1378	9.169e-159	518.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
ZZS2_k127_5142351_2	296591.Bpro_2193	4.435e-84	293.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,4AB3M@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
ZZS2_k127_5142351_0	478741.JAFS01000001_gene2106	3.089e-186	589.0	COG0498@1|root,COG0498@2|Bacteria,46TYU@74201|Verrucomicrobia,37G8J@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_5142351_5	497964.CfE428DRAFT_3330	9.154e-31	124.0	COG1977@1|root,COG1977@2|Bacteria,46WD9@74201|Verrucomicrobia	74201|Verrucomicrobia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ZZS2_k127_5142351_6	497964.CfE428DRAFT_3331	1.343e-25	110.0	COG1135@1|root,COG1135@2|Bacteria,46WAD@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	NIL
ZZS2_k127_5157222_6	293826.Amet_0190	2.744e-17	99.0	COG5337@1|root,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia,36RHJ@31979|Clostridiaceae	186801|Clostridia	M	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
ZZS2_k127_5157222_1	1396141.BATP01000043_gene1929	6.363e-108	399.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_5157222_5	1396141.BATP01000059_gene2521	4.993e-20	108.0	COG2133@1|root,COG2931@1|root,COG3055@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,4.2.2.2	ko:K00428,ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin,fn3
ZZS2_k127_5157222_7	1121920.AUAU01000009_gene1881	4.783e-12	82.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_5157222_2	1396141.BATP01000032_gene4286	1.91e-70	275.0	COG3210@1|root,COG3507@1|root,COG4625@1|root,COG3210@2|Bacteria,COG3507@2|Bacteria,COG4625@2|Bacteria,46UNM@74201|Verrucomicrobia,2IVJ3@203494|Verrucomicrobiae	74201|Verrucomicrobia	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
ZZS2_k127_5157222_4	1280390.CBQR020000058_gene1137	3.717e-29	136.0	COG3533@1|root,COG3533@2|Bacteria,1U157@1239|Firmicutes,4HT9T@91061|Bacilli,26UV2@186822|Paenibacillaceae	91061|Bacilli	G	Concanavalin A-like lectin/glucanases superfamily	M1-853	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_5157222_3	1396141.BATP01000032_gene4286	9.064e-55	220.0	COG3210@1|root,COG3507@1|root,COG4625@1|root,COG3210@2|Bacteria,COG3507@2|Bacteria,COG4625@2|Bacteria,46UNM@74201|Verrucomicrobia,2IVJ3@203494|Verrucomicrobiae	74201|Verrucomicrobia	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
ZZS2_k127_5157222_0	1396141.BATP01000021_gene141	6.254e-173	556.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnA	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
ZZS2_k127_5159930_2	522373.Smlt3912	2.556e-204	651.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales	135614|Xanthomonadales	M	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS2_k127_5159930_0	234267.Acid_7007	1.747e-311	978.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,GHL6,Glyco_hydro_42M,Polysacc_deac_1
ZZS2_k127_5159930_4	481448.Minf_2259	1.606e-73	257.0	COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,37GKS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ZZS2_k127_5159930_7	1236542.BALM01000003_gene530	2.459e-16	83.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,2QCGS@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0235 family	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
ZZS2_k127_5159930_5	289376.THEYE_A2008	6.672e-48	197.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,3J0XC@40117|Nitrospirae	40117|Nitrospirae	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_5159930_8	317619.ANKN01000027_gene1700	6.592e-07	60.0	COG4254@1|root,COG4254@2|Bacteria,1G662@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
ZZS2_k127_5159930_6	497964.CfE428DRAFT_2202	2.576e-37	160.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_5159930_1	497964.CfE428DRAFT_2506	5.612e-247	772.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
ZZS2_k127_5159930_3	234267.Acid_6565	7.259e-118	390.0	COG3386@1|root,COG3386@2|Bacteria,3Y6WN@57723|Acidobacteria	57723|Acidobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5159930_9	1123242.JH636435_gene1408	0.0008077	46.0	COG1520@1|root,COG1520@2|Bacteria,2IYD4@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_518200_5	1385511.N783_12315	5.586e-11	67.0	COG2193@1|root,COG2193@2|Bacteria,1UJ3Q@1239|Firmicutes	1239|Firmicutes	P	PFAM Ferritin Dps	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
ZZS2_k127_518200_2	234267.Acid_1860	1.123e-34	145.0	COG4271@1|root,COG4271@2|Bacteria,3Y91W@57723|Acidobacteria	57723|Acidobacteria	K	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like
ZZS2_k127_518200_0	1192124.LIG30_1791	8.595e-178	562.0	COG0604@1|root,COG0604@2|Bacteria,1R8NX@1224|Proteobacteria,2W0KY@28216|Betaproteobacteria,1K4PK@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
ZZS2_k127_518200_1	926560.KE387023_gene3015	4.611e-44	179.0	COG3055@1|root,COG3055@2|Bacteria,1WK3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
ZZS2_k127_518200_6	1207063.P24_01125	1.108e-07	54.0	COG2931@1|root,COG4625@1|root,COG2931@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Big_5,Cadherin,HemolysinCabind,PATR,Peptidase_M10_C
ZZS2_k127_518200_7	1396141.BATP01000029_gene2272	9.945e-06	52.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF11,DUF4347
ZZS2_k127_518200_3	530564.Psta_3055	2.494e-23	102.0	2EJMY@1|root,33DCV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_518200_8	1396141.BATP01000034_gene4198	0.0003978	48.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_518200_4	9978.XP_004592700.1	4.442e-23	110.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTVB@33213|Bilateria,4845F@7711|Chordata,48VXT@7742|Vertebrata,3JDTM@40674|Mammalia,35IJ6@314146|Euarchontoglires	33208|Metazoa	T	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	LRP6	GO:0000003,GO:0000902,GO:0000904,GO:0001101,GO:0001501,GO:0001654,GO:0001664,GO:0001667,GO:0001702,GO:0001745,GO:0001756,GO:0001763,GO:0001837,GO:0001838,GO:0001841,GO:0001843,GO:0001932,GO:0001933,GO:0001947,GO:0002009,GO:0002011,GO:0002053,GO:0002165,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003143,GO:0003306,GO:0003307,GO:0003308,GO:0003344,GO:0003401,GO:0003674,GO:0004857,GO:0004888,GO:0005041,GO:0005102,GO:0005109,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0005901,GO:0006355,GO:0006357,GO:0006469,GO:0006810,GO:0006869,GO:0006873,GO:0006874,GO:0006875,GO:0006897,GO:0006898,GO:0006928,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007204,GO:0007267,GO:0007268,GO:0007275,GO:0007350,GO:0007365,GO:0007367,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007405,GO:0007417,GO:0007420,GO:0007423,GO:0007444,GO:0007447,GO:0007472,GO:0007476,GO:0007507,GO:0007548,GO:0007552,GO:0007560,GO:0007584,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008104,GO:0008150,GO:0008283,GO:0008284,GO:0008285,GO:0008587,GO:0009605,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009799,GO:0009826,GO:0009855,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010001,GO:0010008,GO:0010033,GO:0010171,GO:0010243,GO:0010464,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010656,GO:0010660,GO:0010720,GO:0010876,GO:0010941,GO:0010942,GO:0010975,GO:0010976,GO:0012505,GO:0014020,GO:0014029,GO:0014033,GO:0014070,GO:0015026,GO:0015850,GO:0015918,GO:0016020,GO:0016043,GO:0016049,GO:0016055,GO:0016192,GO:0016202,GO:0016331,GO:0016477,GO:0017145,GO:0017147,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019534,GO:0019725,GO:0021532,GO:0021535,GO:0021536,GO:0021537,GO:0021543,GO:0021549,GO:0021575,GO:0021587,GO:0021794,GO:0021795,GO:0021861,GO:0021872,GO:0021873,GO:0021874,GO:0021885,GO:0021903,GO:0021915,GO:0021932,GO:0021943,GO:0021953,GO:0021987,GO:0022008,GO:0022029,GO:0022037,GO:0022411,GO:0022414,GO:0022603,GO:0022610,GO:0022612,GO:0022857,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030003,GO:0030111,GO:0030154,GO:0030177,GO:0030178,GO:0030182,GO:0030228,GO:0030234,GO:0030278,GO:0030301,GO:0030326,GO:0030879,GO:0030900,GO:0030901,GO:0030902,GO:0030917,GO:0031076,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031399,GO:0031400,GO:0031410,GO:0031667,GO:0031901,GO:0031982,GO:0032268,GO:0032269,GO:0032365,GO:0032366,GO:0032367,GO:0032501,GO:0032502,GO:0032984,GO:0032989,GO:0032991,GO:0033036,GO:0033273,GO:0033673,GO:0033993,GO:0034103,GO:0034105,GO:0034185,GO:0034391,GO:0034392,GO:0034613,GO:0035050,GO:0035051,GO:0035107,GO:0035108,GO:0035112,GO:0035113,GO:0035114,GO:0035115,GO:0035116,GO:0035120,GO:0035136,GO:0035137,GO:0035148,GO:0035218,GO:0035220,GO:0035223,GO:0035239,GO:0035261,GO:0035282,GO:0035295,GO:0036314,GO:0036315,GO:0036342,GO:0036445,GO:0036477,GO:0038023,GO:0038024,GO:0040007,GO:0040011,GO:0042063,GO:0042074,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042475,GO:0042476,GO:0042493,GO:0042592,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042981,GO:0043009,GO:0043010,GO:0043025,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043235,GO:0043549,GO:0043933,GO:0044092,GO:0044093,GO:0044297,GO:0044332,GO:0044335,GO:0044340,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044853,GO:0045121,GO:0045124,GO:0045202,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045599,GO:0045664,GO:0045666,GO:0045778,GO:0045780,GO:0045787,GO:0045843,GO:0045859,GO:0045893,GO:0045935,GO:0045936,GO:0045944,GO:0045992,GO:0045995,GO:0046849,GO:0046850,GO:0046852,GO:0046907,GO:0046983,GO:0048048,GO:0048070,GO:0048073,GO:0048076,GO:0048103,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048593,GO:0048596,GO:0048598,GO:0048608,GO:0048634,GO:0048635,GO:0048646,GO:0048699,GO:0048705,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048754,GO:0048762,GO:0048771,GO:0048806,GO:0048856,GO:0048863,GO:0048869,GO:0048870,GO:0048878,GO:0050678,GO:0050680,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050877,GO:0050890,GO:0050896,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051301,GO:0051338,GO:0051348,GO:0051480,GO:0051593,GO:0051641,GO:0051649,GO:0051674,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0051962,GO:0055024,GO:0055026,GO:0055057,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060019,GO:0060021,GO:0060026,GO:0060039,GO:0060041,GO:0060042,GO:0060059,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0060429,GO:0060438,GO:0060439,GO:0060443,GO:0060444,GO:0060485,GO:0060534,GO:0060535,GO:0060536,GO:0060541,GO:0060548,GO:0060560,GO:0060562,GO:0060592,GO:0060596,GO:0060603,GO:0060606,GO:0060788,GO:0060828,GO:0061053,GO:0061138,GO:0061180,GO:0061307,GO:0061310,GO:0061311,GO:0061316,GO:0061324,GO:0061351,GO:0061371,GO:0061448,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071542,GO:0071696,GO:0071697,GO:0071702,GO:0071840,GO:0071900,GO:0071901,GO:0071936,GO:0071944,GO:0072089,GO:0072175,GO:0072359,GO:0072503,GO:0072507,GO:0072657,GO:0072659,GO:0080090,GO:0090009,GO:0090090,GO:0090118,GO:0090175,GO:0090178,GO:0090244,GO:0090245,GO:0090254,GO:0090263,GO:0090596,GO:0097305,GO:0097306,GO:0097458,GO:0097708,GO:0098588,GO:0098589,GO:0098590,GO:0098609,GO:0098657,GO:0098771,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120035,GO:0198738,GO:1901219,GO:1901220,GO:1901698,GO:1901700,GO:1901701,GO:1901861,GO:1901862,GO:1901963,GO:1901998,GO:1902680,GO:1903506,GO:1903508,GO:1904412,GO:1904413,GO:1904886,GO:1904928,GO:1904948,GO:1904953,GO:1905114,GO:1905276,GO:1905277,GO:1905330,GO:1905331,GO:1990778,GO:1990851,GO:1990909,GO:2000026,GO:2000027,GO:2000050,GO:2000051,GO:2000053,GO:2000055,GO:2000095,GO:2000112,GO:2000136,GO:2000148,GO:2000149,GO:2000150,GO:2000151,GO:2000159,GO:2000160,GO:2000161,GO:2000162,GO:2000163,GO:2000164,GO:2000165,GO:2000166,GO:2000167,GO:2000168,GO:2000826,GO:2001141	-	ko:K03068	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	FXa_inhibition,Ldl_recept_a,Ldl_recept_b
ZZS2_k127_5198670_5	525904.Tter_2139	1.653e-67	244.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_5198670_8	136273.GY22_01435	3.274e-40	158.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,1W8TF@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
ZZS2_k127_5198670_2	525904.Tter_2133	1.687e-135	437.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
ZZS2_k127_5198670_11	1267533.KB906735_gene4652	7.323e-12	76.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_5198670_10	1267533.KB906735_gene4653	9.663e-23	109.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_5198670_4	314230.DSM3645_18261	2.104e-103	366.0	COG1520@1|root,COG1520@2|Bacteria,2IXD2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_5198670_6	1170562.Cal6303_2739	1.897e-65	251.0	COG0520@1|root,COG1672@1|root,COG2319@1|root,COG0520@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
ZZS2_k127_5198670_3	1117314.PCIT_13169	9.625e-104	362.0	COG3568@1|root,COG3568@2|Bacteria,1R3X8@1224|Proteobacteria,1RZYH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
ZZS2_k127_5198670_7	1210884.HG799464_gene10801	1.695e-56	213.0	COG4948@1|root,COG4948@2|Bacteria,2IX42@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase muconate lactonizing enzyme	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_5198670_9	344747.PM8797T_29872	9.307e-26	118.0	COG2267@1|root,COG2267@2|Bacteria,2IZH7@203682|Planctomycetes	203682|Planctomycetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ZZS2_k127_5198670_0	886293.Sinac_7111	3.176e-320	1012.0	COG2010@1|root,COG2010@2|Bacteria,2IYDW@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_5198670_1	886293.Sinac_7112	1.283e-231	724.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5205716_4	497964.CfE428DRAFT_4151	8.395e-68	233.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
ZZS2_k127_5205716_0	240016.ABIZ01000001_gene4797	4.283e-163	526.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
ZZS2_k127_5205716_2	497964.CfE428DRAFT_1992	6.012e-131	424.0	COG3938@1|root,COG3938@2|Bacteria,46U8C@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Proline racemase	-	-	-	-	-	-	-	-	-	-	-	-	Pro_racemase
ZZS2_k127_5205716_1	1403819.BATR01000090_gene2623	2.82e-152	492.0	COG0665@1|root,COG0665@2|Bacteria,46TXP@74201|Verrucomicrobia,2IV40@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
ZZS2_k127_5205716_3	886293.Sinac_6999	2.773e-127	427.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IY8M@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF885,Peptidase_S9,VHL
ZZS2_k127_5218494_3	497964.CfE428DRAFT_1943	7.895e-128	417.0	COG2133@1|root,COG2133@2|Bacteria,46THQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_5218494_5	497964.CfE428DRAFT_2392	4.106e-91	306.0	COG0266@1|root,COG0266@2|Bacteria,46SKI@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
ZZS2_k127_5218494_7	316067.Geob_1986	3.677e-13	81.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA-1	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ZZS2_k127_5218494_0	1125863.JAFN01000001_gene34	4.145e-193	625.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
ZZS2_k127_5218494_1	481448.Minf_0446	1.054e-186	598.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,37G72@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
ZZS2_k127_5218494_6	497964.CfE428DRAFT_1210	4.696e-43	172.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5218494_4	452637.Oter_2822	8.246e-101	343.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
ZZS2_k127_5218494_2	452637.Oter_2821	2.482e-161	533.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia,3K7UF@414999|Opitutae	414999|Opitutae	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
ZZS2_k127_5218494_9	497964.CfE428DRAFT_4965	1.601e-08	61.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_5218494_8	497964.CfE428DRAFT_5892	3.215e-12	68.0	COG4968@1|root,COG4968@2|Bacteria,46Z8X@74201|Verrucomicrobia	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	lspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS2_k127_5285181_8	395493.BegalDRAFT_2935	3.843e-10	64.0	COG1408@1|root,COG1408@2|Bacteria,1RK37@1224|Proteobacteria,1SEEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase activity	yaeI	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
ZZS2_k127_5285181_6	382464.ABSI01000005_gene1380	3.643e-12	78.0	2B7DQ@1|root,320HD@2|Bacteria,46XRQ@74201|Verrucomicrobia,2IWFK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5285181_1	1403819.BATR01000083_gene2420	6.359e-217	682.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,Peptidase_M57
ZZS2_k127_5285181_5	1121861.KB899932_gene35	1.203e-110	403.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2JQ2C@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,Response_reg
ZZS2_k127_5285181_0	240016.ABIZ01000001_gene5249	0.0	1169.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ZZS2_k127_5285181_4	886293.Sinac_6489	3.483e-114	406.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_5285181_3	497964.CfE428DRAFT_2679	1.298e-130	422.0	COG1721@1|root,COG1721@2|Bacteria,46TEC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_5285181_7	926551.KB900717_gene223	8.968e-12	73.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia,1ES7U@1016|Capnocytophaga	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS2_k127_5285181_2	497964.CfE428DRAFT_2676	9.686e-151	483.0	COG0714@1|root,COG0714@2|Bacteria,46UBM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
ZZS2_k127_5287357_13	243924.LT42_23185	6.5e-07	51.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_5287357_1	497964.CfE428DRAFT_5191	8.155e-261	812.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
ZZS2_k127_5287357_10	452637.Oter_2053	2.903e-34	133.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,3K8AV@414999|Opitutae	414999|Opitutae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
ZZS2_k127_5287357_0	497964.CfE428DRAFT_5188	7.621e-304	943.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ZZS2_k127_5287357_2	481448.Minf_2402	1.579e-220	701.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,37GAP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
ZZS2_k127_5287357_8	497964.CfE428DRAFT_5839	1.327e-56	213.0	COG1943@1|root,COG1943@2|Bacteria,46V9J@74201|Verrucomicrobia	2|Bacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Y1_Tnp
ZZS2_k127_5287357_4	497964.CfE428DRAFT_5027	4.738e-143	472.0	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_5287357_5	497964.CfE428DRAFT_2456	1.026e-115	379.0	COG0685@1|root,COG0685@2|Bacteria,46U74@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
ZZS2_k127_5287357_3	497964.CfE428DRAFT_1840	2.224e-218	715.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_5287357_11	278957.ABEA03000040_gene3872	1.766e-19	98.0	2A6GN@1|root,30V9U@2|Bacteria,46YRQ@74201|Verrucomicrobia,3K91W@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5287357_6	1242864.D187_000069	4.59e-77	271.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YZXT@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_5287357_7	497964.CfE428DRAFT_0110	2.744e-58	206.0	COG1595@1|root,COG1595@2|Bacteria,46VNT@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_5287357_9	497964.CfE428DRAFT_0108	5.917e-40	168.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5287357_12	1123242.JH636436_gene262	1.188e-18	89.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_5338274_1	1121920.AUAU01000009_gene1881	6.291e-32	147.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_5338274_0	313603.FB2170_10111	9.085e-83	315.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_5346583_2	290397.Adeh_1209	7.49e-19	93.0	COG0457@1|root,COG4262@1|root,COG0457@2|Bacteria,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42Q43@68525|delta/epsilon subdivisions,2WKQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
ZZS2_k127_5346583_1	663610.JQKO01000001_gene574	7.309e-38	145.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,3NBPH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
ZZS2_k127_5346583_0	497964.CfE428DRAFT_5340	9.905e-42	161.0	COG1595@1|root,COG1595@2|Bacteria,46VME@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5346583_3	1173263.Syn7502_02969	1.18e-14	81.0	COG1917@1|root,COG1917@2|Bacteria,1G6GH@1117|Cyanobacteria	1117|Cyanobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
ZZS2_k127_5375758_10	497964.CfE428DRAFT_5311	6.622e-186	591.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5375758_9	344747.PM8797T_03955	3.447e-190	623.0	COG3064@1|root,COG3064@2|Bacteria,2IWVN@203682|Planctomycetes	203682|Planctomycetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PPC
ZZS2_k127_5375758_3	344747.PM8797T_03960	4.835e-299	938.0	COG5373@1|root,COG5492@1|root,COG5373@2|Bacteria,COG5492@2|Bacteria,2IXP9@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_5375758_19	530564.Psta_2093	5.72e-139	467.0	COG2319@1|root,COG2319@2|Bacteria,2IXJX@203682|Planctomycetes	203682|Planctomycetes	C	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
ZZS2_k127_5375758_36	335543.Sfum_3180	1.432e-61	226.0	COG4861@1|root,COG4861@2|Bacteria,1QEX3@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2
ZZS2_k127_5375758_26	485913.Krac_9014	1.262e-92	310.0	COG0846@1|root,COG0846@2|Bacteria	2|Bacteria	K	NAD+ binding	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
ZZS2_k127_5375758_16	215803.DB30_6572	1.028e-146	498.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria,439DU@68525|delta/epsilon subdivisions,2X4NR@28221|Deltaproteobacteria,2YZBD@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
ZZS2_k127_5375758_48	1396141.BATP01000020_gene90	2.444e-36	141.0	COG1695@1|root,COG1695@2|Bacteria,46WGD@74201|Verrucomicrobia,2IW9N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
ZZS2_k127_5375758_34	1382356.JQMP01000004_gene227	7.452e-64	224.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
ZZS2_k127_5375758_4	234267.Acid_2226	4.722e-274	878.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS2_k127_5375758_31	926554.KI912647_gene1813	3.098e-74	261.0	COG1319@1|root,COG1319@2|Bacteria,1WMAT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
ZZS2_k127_5375758_51	744980.TRICHSKD4_0799	5.892e-31	128.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	carbon monoxide dehydrogenase	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
ZZS2_k127_5375758_41	1562701.BBOF01000059_gene1751	4.971e-49	185.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VKKP@28216|Betaproteobacteria,1K3SX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
ZZS2_k127_5375758_37	583355.Caka_1238	1.979e-58	215.0	COG1984@1|root,COG1984@2|Bacteria,46VNA@74201|Verrucomicrobia,3K9I8@414999|Opitutae	414999|Opitutae	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
ZZS2_k127_5375758_46	997346.HMPREF9374_2988	5.862e-43	165.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,27BWJ@186824|Thermoactinomycetaceae	91061|Bacilli	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
ZZS2_k127_5375758_28	1120985.AUMI01000014_gene769	1.642e-87	295.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
ZZS2_k127_5375758_17	240016.ABIZ01000001_gene4595	1.286e-143	469.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,2ITYH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
ZZS2_k127_5375758_11	497964.CfE428DRAFT_5721	2.226e-178	587.0	COG2133@1|root,COG2133@2|Bacteria,46UAQ@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Laminin_G_3
ZZS2_k127_5375758_29	497964.CfE428DRAFT_4519	5.641e-85	291.0	COG0388@1|root,COG0388@2|Bacteria,46T1B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
ZZS2_k127_5375758_14	1487953.JMKF01000015_gene6238	2.245e-159	511.0	COG0436@1|root,COG0436@2|Bacteria,1G24E@1117|Cyanobacteria,1H6X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
ZZS2_k127_5375758_53	1121346.KB899858_gene334	1.257e-26	125.0	COG1409@1|root,COG1621@1|root,COG4632@1|root,COG5184@1|root,COG1409@2|Bacteria,COG1621@2|Bacteria,COG4632@2|Bacteria,COG5184@2|Bacteria,1VE4R@1239|Firmicutes,4HV48@91061|Bacilli,27727@186822|Paenibacillaceae	91061|Bacilli	G	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,DUF5011,Glyco_hydro_59,Metallophos,NAGPA,Pur_ac_phosph_N,SLH
ZZS2_k127_5375758_40	163908.KB235896_gene1675	4.272e-51	196.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,1FZVW@1117|Cyanobacteria,1HMS2@1161|Nostocales	1117|Cyanobacteria	T	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
ZZS2_k127_5375758_54	497964.CfE428DRAFT_2504	1.815e-22	100.0	COG1534@1|root,COG1534@2|Bacteria,46T8G@74201|Verrucomicrobia	74201|Verrucomicrobia	J	CRS1_YhbY	-	-	-	-	-	-	-	-	-	-	-	-	CRS1_YhbY
ZZS2_k127_5375758_6	886293.Sinac_1862	3.222e-219	694.0	COG2234@1|root,COG2234@2|Bacteria,2IWTP@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_5375758_45	234267.Acid_2426	6.905e-45	171.0	COG5588@1|root,COG5588@2|Bacteria,3Y7RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
ZZS2_k127_5375758_27	234267.Acid_2421	2.497e-88	306.0	COG1319@1|root,COG1319@2|Bacteria,3Y3NU@57723|Acidobacteria	57723|Acidobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
ZZS2_k127_5375758_7	204669.Acid345_0762	1.018e-216	696.0	COG1529@1|root,COG1529@2|Bacteria,3Y2ME@57723|Acidobacteria,2JIZI@204432|Acidobacteriia	204432|Acidobacteriia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS2_k127_5375758_38	204669.Acid345_0761	1.667e-55	201.0	COG2080@1|root,COG2080@2|Bacteria,3Y4DP@57723|Acidobacteria,2JJ2F@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S -binding	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2,TAT_signal
ZZS2_k127_5375758_39	1396141.BATP01000057_gene2939	3.413e-51	196.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
ZZS2_k127_5375758_49	240016.ABIZ01000001_gene1023	2.836e-35	143.0	COG0468@1|root,COG0468@2|Bacteria,46T7P@74201|Verrucomicrobia,2IUW3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	-	-	-	-	-	-	-	-	-	-	-	-	RecA
ZZS2_k127_5375758_25	452637.Oter_4054	3.827e-94	327.0	COG0389@1|root,COG0389@2|Bacteria,46SR8@74201|Verrucomicrobia,3K9GX@414999|Opitutae	414999|Opitutae	L	impB/mucB/samB family	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	-
ZZS2_k127_5375758_60	1210884.HG799464_gene10415	4.912e-12	77.0	COG0322@1|root,COG0322@2|Bacteria,2IYUK@203682|Planctomycetes	203682|Planctomycetes	L	GIY-YIG type nucleases (URI domain)	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR
ZZS2_k127_5375758_2	382464.ABSI01000011_gene2935	0.0	1077.0	COG0587@1|root,COG0587@2|Bacteria,46S6W@74201|Verrucomicrobia,2IU0A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Bacterial DNA polymerase III alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS2_k127_5375758_30	1122603.ATVI01000008_gene2293	1.89e-83	286.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,1XCF5@135614|Xanthomonadales	135614|Xanthomonadales	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_5375758_20	489825.LYNGBM3L_21200	1.517e-136	455.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_5375758_0	240016.ABIZ01000001_gene2256	0.0	1399.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
ZZS2_k127_5375758_55	497964.CfE428DRAFT_1834	5.58e-22	105.0	2CIV9@1|root,34A52@2|Bacteria	2|Bacteria	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
ZZS2_k127_5375758_32	497964.CfE428DRAFT_0556	4.307e-73	256.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,46TMI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	SMP-30 Gluconolaconase LRE domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SGL
ZZS2_k127_5375758_57	349741.Amuc_1842	5.152e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,46WAM@74201|Verrucomicrobia,2IWJD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
ZZS2_k127_5375758_59	316067.Geob_3376	1.791e-12	82.0	COG1807@1|root,COG1807@2|Bacteria,1N8ZV@1224|Proteobacteria,42WB6@68525|delta/epsilon subdivisions,2WRTT@28221|Deltaproteobacteria,43TNH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
ZZS2_k127_5375758_50	1396141.BATP01000007_gene5780	4.601e-34	138.0	COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia,2IUHJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
ZZS2_k127_5375758_18	497964.CfE428DRAFT_3655	1.413e-141	459.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia	74201|Verrucomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
ZZS2_k127_5375758_43	278957.ABEA03000099_gene817	1.705e-45	176.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia,3K7Y0@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
ZZS2_k127_5375758_24	497964.CfE428DRAFT_0193	4.706e-113	371.0	COG1210@1|root,COG1210@2|Bacteria,46S5P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS2_k127_5375758_1	497964.CfE428DRAFT_5324	0.0	1107.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
ZZS2_k127_5375758_21	497964.CfE428DRAFT_6499	6.313e-124	422.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MEDS,PAS_4,PAS_9,Response_reg
ZZS2_k127_5375758_8	497964.CfE428DRAFT_0230	7.832e-216	716.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,46TGZ@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_5375758_13	926560.KE387023_gene1701	1.264e-159	533.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_5375758_58	1292035.H476_2081	4.67e-13	81.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,25QP7@186804|Peptostreptococcaceae	186801|Clostridia	K	response regulator	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_5375758_47	497964.CfE428DRAFT_5353	4.432e-39	162.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
ZZS2_k127_5375758_42	518766.Rmar_1932	7.781e-49	179.0	COG0537@1|root,COG0537@2|Bacteria,4NEYS@976|Bacteroidetes,1FJAW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
ZZS2_k127_5375758_23	497964.CfE428DRAFT_6337	1.278e-115	381.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
ZZS2_k127_5375758_56	945713.IALB_1565	1.392e-16	87.0	COG0319@1|root,COG0319@2|Bacteria	2|Bacteria	C	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029	-	-	-	UPF0054
ZZS2_k127_5375758_52	240016.ABIZ01000001_gene925	5.109e-28	121.0	COG1381@1|root,COG1381@2|Bacteria,46VUW@74201|Verrucomicrobia,2IUNX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Recombination protein O N terminal	-	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
ZZS2_k127_5375758_5	497964.CfE428DRAFT_4831	1.777e-232	734.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
ZZS2_k127_5375758_15	1156937.MFUM_700088	7.65e-150	490.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,37G4E@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
ZZS2_k127_5375758_22	370438.PTH_1260	1.788e-121	402.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,260S5@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
ZZS2_k127_5375758_35	497964.CfE428DRAFT_4834	1.443e-62	227.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
ZZS2_k127_5375758_12	269799.Gmet_2724	1.086e-168	555.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43UGC@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS2_k127_5375758_33	530564.Psta_2427	4.151e-64	228.0	COG2755@1|root,COG2755@2|Bacteria,2IZ2H@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_5375758_44	1122176.KB903587_gene4522	3.387e-45	178.0	COG0739@1|root,COG3291@1|root,COG0739@2|Bacteria,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1J0XQ@117747|Sphingobacteriia	976|Bacteroidetes	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_19	1123242.JH636434_gene3426	2.968e-92	311.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
ZZS2_k127_5396409_38	247490.KSU1_D0981	4.37e-20	101.0	COG0457@1|root,COG0457@2|Bacteria	247490.KSU1_D0981|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_7	243090.RB11088	6.701e-205	655.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_5396409_1	344747.PM8797T_03935	0.0	1098.0	COG0457@1|root,COG0457@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
ZZS2_k127_5396409_6	497964.CfE428DRAFT_4782	1.73e-205	650.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	hpnJ	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
ZZS2_k127_5396409_8	497964.CfE428DRAFT_6681	2.21e-191	608.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
ZZS2_k127_5396409_39	1121447.JONL01000003_gene3289	5.286e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria,2MBFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
ZZS2_k127_5396409_30	644968.DFW101_0743	4.288e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,1Q1ZZ@1224|Proteobacteria,42USA@68525|delta/epsilon subdivisions,2WQ2Q@28221|Deltaproteobacteria,2MB9I@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS2_k127_5396409_21	329726.AM1_4383	2.501e-86	299.0	COG0823@1|root,COG0823@2|Bacteria,1G28F@1117|Cyanobacteria	1117|Cyanobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_2	583355.Caka_1736	0.0	1089.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_5396409_37	1121405.dsmv_0737	2.508e-21	112.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
ZZS2_k127_5396409_15	1121904.ARBP01000013_gene373	2.484e-117	398.0	COG2730@1|root,COG2730@2|Bacteria,4P1NI@976|Bacteroidetes,47TT8@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
ZZS2_k127_5396409_9	573413.Spirs_4003	4.711e-187	608.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
ZZS2_k127_5396409_13	1122603.ATVI01000006_gene805	3.337e-144	482.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	shp	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,DUF1924
ZZS2_k127_5396409_27	13333.ERN03299	1.93e-54	211.0	COG0637@1|root,KOG2177@1|root,KOG2177@2759|Eukaryota,KOG2914@2759|Eukaryota,37MAK@33090|Viridiplantae,3GD1A@35493|Streptophyta	35493|Streptophyta	O	NHL repeat-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
ZZS2_k127_5396409_36	1380394.JADL01000003_gene5127	6.588e-22	111.0	COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria	1224|Proteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS2_k127_5396409_24	1403819.BATR01000104_gene3591	2.936e-69	261.0	COG3063@1|root,COG3063@2|Bacteria,46UEF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_5	1123508.JH636442_gene4052	9.601e-221	707.0	COG2010@1|root,COG2010@2|Bacteria,2IXUQ@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_5396409_4	1123508.JH636442_gene4053	8.34e-222	696.0	COG4102@1|root,COG4102@2|Bacteria,2IYDS@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5396409_16	1210884.HG799473_gene15064	6.486e-111	376.0	COG0477@1|root,COG0477@2|Bacteria,2IX7U@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
ZZS2_k127_5396409_32	1500894.JQNN01000001_gene2758	8.767e-40	160.0	COG2819@1|root,COG2819@2|Bacteria,1PTJI@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_5396409_33	497964.CfE428DRAFT_2455	1.302e-38	151.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
ZZS2_k127_5396409_26	498848.TaqDRAFT_4878	9.452e-64	244.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_28	382464.ABSI01000011_gene2595	1.089e-53	207.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
ZZS2_k127_5396409_12	382464.ABSI01000011_gene2604	1.297e-146	478.0	COG2204@1|root,COG2204@2|Bacteria,46TZX@74201|Verrucomicrobia,2IV20@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_5396409_22	215803.DB30_7981	2.835e-73	255.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,43A1N@68525|delta/epsilon subdivisions,2X25S@28221|Deltaproteobacteria,2YYJ4@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase dehydratase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_5396409_25	497964.CfE428DRAFT_4864	1.529e-64	229.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_35	338966.Ppro_2456	7.724e-28	127.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
ZZS2_k127_5396409_14	1396418.BATQ01000113_gene4641	1.1e-121	409.0	COG1657@1|root,COG1657@2|Bacteria,46U97@74201|Verrucomicrobia,2ITWF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_5396409_23	794903.OPIT5_13875	4.18e-71	251.0	COG5616@1|root,COG5616@2|Bacteria,46XZ9@74201|Verrucomicrobia,3K8NU@414999|Opitutae	414999|Opitutae	S	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
ZZS2_k127_5396409_11	886293.Sinac_4596	1.342e-173	564.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_41	1123279.ATUS01000001_gene1995	3.781e-07	64.0	COG3266@1|root,COG3266@2|Bacteria,1NNA4@1224|Proteobacteria	1224|Proteobacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_18	448385.sce1378	1.035e-94	316.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria,2YVI4@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS2_k127_5396409_0	530564.Psta_3897	0.0	1146.0	COG2609@1|root,COG2609@2|Bacteria,2IXXY@203682|Planctomycetes	203682|Planctomycetes	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
ZZS2_k127_5396409_29	1210884.HG799462_gene7872	2.03e-51	203.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS2_k127_5396409_17	330214.NIDE2556	1.189e-100	335.0	COG2877@1|root,COG2877@2|Bacteria,3J0AK@40117|Nitrospirae	40117|Nitrospirae	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
ZZS2_k127_5396409_31	1198452.Jab_1c08220	1.197e-40	156.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,473QF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	haloacid dehalogenase-like hydrolase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
ZZS2_k127_5396409_20	671143.DAMO_1189	9.961e-89	305.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
ZZS2_k127_5396409_40	382464.ABSI01000007_gene4120	7.64e-10	66.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia,2IURV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5396409_3	886293.Sinac_6369	3.628e-245	779.0	COG0551@1|root,COG0551@2|Bacteria,2IXB2@203682|Planctomycetes	203682|Planctomycetes	L	Ca-dependent carbohydrate-binding module xylan-binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
ZZS2_k127_5396409_34	84531.JMTZ01000109_gene383	5.398e-31	131.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
ZZS2_k127_5396409_10	886293.Sinac_6370	3.199e-175	563.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_5401707_0	1144275.COCOR_01988	4.416e-49	201.0	COG3863@1|root,COG3863@2|Bacteria,1NCR6@1224|Proteobacteria,42WW5@68525|delta/epsilon subdivisions,2X5AP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
ZZS2_k127_5401707_1	1242864.D187_006584	6.921e-43	181.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria	1224|Proteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
ZZS2_k127_5401707_2	1107311.Q767_03065	3.623e-38	157.0	2CSRV@1|root,32SRR@2|Bacteria,4NTI6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NlpE
ZZS2_k127_5425798_0	1297742.A176_01664	3.779e-108	364.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YW82@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_5425798_1	278957.ABEA03000086_gene2502	1.308e-98	333.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,3K7W3@414999|Opitutae	414999|Opitutae	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
ZZS2_k127_5425798_3	382464.ABSI01000020_gene273	5.996e-16	84.0	COG4576@1|root,COG4576@2|Bacteria,46WMY@74201|Verrucomicrobia	74201|Verrucomicrobia	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
ZZS2_k127_5425798_2	1123242.JH636435_gene1239	3.501e-19	89.0	COG4576@1|root,COG4576@2|Bacteria,2J0UQ@203682|Planctomycetes	203682|Planctomycetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
ZZS2_k127_54488_2	649638.Trad_2723	3.844e-68	242.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
ZZS2_k127_54488_3	1396418.BATQ01000065_gene1631	8.844e-58	204.0	COG0346@1|root,COG0346@2|Bacteria,46VSK@74201|Verrucomicrobia,2IUXF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_54488_4	235909.GK3175	1.388e-29	132.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4HDPI@91061|Bacilli,1WEDQ@129337|Geobacillus	91061|Bacilli	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
ZZS2_k127_54488_0	497964.CfE428DRAFT_4840	7.196e-186	604.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
ZZS2_k127_54488_1	519989.ECTPHS_14004	1.866e-118	393.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WVZP@135613|Chromatiales	135613|Chromatiales	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
ZZS2_k127_54488_5	445972.ANACOL_00901	7.828e-05	46.0	COG2071@1|root,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
ZZS2_k127_5472331_8	215803.DB30_6964	7.117e-146	474.0	COG3507@1|root,COG3507@2|Bacteria,1MWY2@1224|Proteobacteria,4391R@68525|delta/epsilon subdivisions,2X479@28221|Deltaproteobacteria,2YYED@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
ZZS2_k127_5472331_1	661478.OP10G_1743	5.032e-265	840.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,RicinB_lectin_2
ZZS2_k127_5472331_5	497964.CfE428DRAFT_1051	2.337e-204	646.0	COG3119@1|root,COG3119@2|Bacteria,46TFM@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5472331_0	497964.CfE428DRAFT_1050	3.117e-279	884.0	COG4654@1|root,COG4654@2|Bacteria,46UM8@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_5472331_6	1047013.AQSP01000126_gene2737	3.146e-202	636.0	COG0673@1|root,COG0673@2|Bacteria,2NRVS@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_5472331_11	748247.AZKH_4546	1.149e-95	325.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,2VKZ8@28216|Betaproteobacteria,2KU6J@206389|Rhodocyclales	206389|Rhodocyclales	L	PFAM Uracil-DNA glycosylase superfamily	smuG	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
ZZS2_k127_5472331_19	1396141.BATP01000030_gene3719	1.621e-22	116.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
ZZS2_k127_5472331_2	583355.Caka_1736	8.016e-246	834.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_5472331_18	1121920.AUAU01000009_gene1881	6.688e-25	124.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_5472331_25	1396418.BATQ01000022_gene5235	0.0001616	57.0	COG0508@1|root,COG3147@1|root,COG3266@1|root,COG0508@2|Bacteria,COG3147@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	-
ZZS2_k127_5472331_22	794903.OPIT5_20130	5.944e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_20130|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5472331_3	278957.ABEA03000010_gene3912	6.526e-237	746.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
ZZS2_k127_5472331_10	794903.OPIT5_06520	1.794e-137	449.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,3K7HI@414999|Opitutae	414999|Opitutae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ZZS2_k127_5472331_16	452637.Oter_0587	3.9e-61	223.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,3K7YX@414999|Opitutae	414999|Opitutae	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
ZZS2_k127_5472331_13	1382306.JNIM01000001_gene2595	1.301e-78	286.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_5472331_4	497964.CfE428DRAFT_0257	7.928e-222	721.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
ZZS2_k127_5472331_14	497964.CfE428DRAFT_0263	1.41e-75	263.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
ZZS2_k127_5472331_24	929558.SMGD1_1523	7.005e-10	68.0	COG1280@1|root,COG1280@2|Bacteria,1RGDP@1224|Proteobacteria,42SFM@68525|delta/epsilon subdivisions,2YPK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	LysE family	-	-	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
ZZS2_k127_5472331_7	452637.Oter_0554	5.41e-161	519.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
ZZS2_k127_5472331_17	1121423.JONT01000003_gene976	1.501e-28	130.0	COG2041@1|root,COG5337@1|root,COG2041@2|Bacteria,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
ZZS2_k127_5472331_9	1123242.JH636435_gene2797	8.857e-139	456.0	COG2010@1|root,COG2010@2|Bacteria,2J547@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5472331_15	396588.Tgr7_2029	2.732e-63	226.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
ZZS2_k127_5472331_21	1214101.BN159_6008	1.657e-16	83.0	COG5646@1|root,COG5646@2|Bacteria,2IMR2@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS2_k127_5472331_12	278957.ABEA03000104_gene318	8.044e-86	296.0	COG0673@1|root,COG0673@2|Bacteria,46UTE@74201|Verrucomicrobia,3K8EQ@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_5472331_23	1506583.JQJY01000008_gene4016	2.403e-13	80.0	COG2273@1|root,COG2273@2|Bacteria,4NKMT@976|Bacteroidetes,1IJUZ@117743|Flavobacteriia,2NV1U@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
ZZS2_k127_5474518_17	56107.Cylst_4795	2.679e-27	119.0	COG0524@1|root,COG0524@2|Bacteria,1G2YU@1117|Cyanobacteria,1HJ1G@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ZZS2_k127_5474518_7	452637.Oter_0728	1.985e-77	267.0	COG1187@1|root,COG1187@2|Bacteria,46V36@74201|Verrucomicrobia,3K7NW@414999|Opitutae	414999|Opitutae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_5474518_15	794903.OPIT5_05525	1.969e-38	149.0	2FADU@1|root,342N6@2|Bacteria,46VMD@74201|Verrucomicrobia,3K81H@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
ZZS2_k127_5474518_3	243090.RB10165	9.274e-159	530.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
ZZS2_k127_5474518_12	452637.Oter_0798	3.992e-59	218.0	COG0741@1|root,COG0741@2|Bacteria,46XU1@74201|Verrucomicrobia,3K83P@414999|Opitutae	414999|Opitutae	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SLT
ZZS2_k127_5474518_8	521674.Plim_2940	5.169e-75	258.0	COG1387@1|root,COG1387@2|Bacteria,2IZCF@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_5474518_4	452637.Oter_1503	1.111e-133	437.0	COG2081@1|root,COG2081@2|Bacteria,46TWE@74201|Verrucomicrobia,3K7FU@414999|Opitutae	414999|Opitutae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
ZZS2_k127_5474518_2	452637.Oter_0239	4.181e-198	623.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
ZZS2_k127_5474518_20	1168059.KB899087_gene1061	9.06e-05	49.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
ZZS2_k127_5474518_18	452637.Oter_0238	1.088e-07	56.0	COG0690@1|root,COG0690@2|Bacteria,46WU6@74201|Verrucomicrobia,3K8FP@414999|Opitutae	414999|Opitutae	U	Belongs to the SecE SEC61-gamma family	-	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
ZZS2_k127_5474518_10	382464.ABSI01000011_gene2687	7.509e-63	220.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,2IU6S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
ZZS2_k127_5474518_11	1156937.MFUM_210036	3.574e-60	210.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,37GN5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
ZZS2_k127_5474518_5	497964.CfE428DRAFT_5605	1.939e-89	301.0	COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
ZZS2_k127_5474518_14	1403819.BATR01000191_gene6561	2.404e-43	164.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
ZZS2_k127_5474518_16	1122137.AQXF01000009_gene10	1.401e-31	128.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
ZZS2_k127_5474518_1	313628.LNTAR_19662	0.0	1463.0	COG0085@1|root,COG0085@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
ZZS2_k127_5474518_0	481448.Minf_0805	0.0	1989.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,37G3C@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
ZZS2_k127_5474518_9	794903.OPIT5_02450	3.81e-66	228.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
ZZS2_k127_5474518_13	1156937.MFUM_870046	4.308e-58	205.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,37GT5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
ZZS2_k127_5474518_6	497964.CfE428DRAFT_0484	1.349e-78	266.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_5477269_0	497964.CfE428DRAFT_3698	3.019e-133	443.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
ZZS2_k127_5477269_6	1396141.BATP01000003_gene5274	0.0002039	48.0	COG5492@1|root,COG5492@2|Bacteria,46SD1@74201|Verrucomicrobia,2IVJE@203494|Verrucomicrobiae	74201|Verrucomicrobia	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_5477269_5	344747.PM8797T_03960	8.304e-18	86.0	COG5373@1|root,COG5492@1|root,COG5373@2|Bacteria,COG5492@2|Bacteria,2IXP9@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_5477269_4	1047013.AQSP01000126_gene2738	1.603e-29	130.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
ZZS2_k127_5477269_1	1047013.AQSP01000126_gene2737	5.976e-107	362.0	COG0673@1|root,COG0673@2|Bacteria,2NRVS@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_5477269_3	1267535.KB906767_gene4863	5.607e-65	228.0	COG3554@1|root,COG3554@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
ZZS2_k127_5477269_2	314230.DSM3645_14810	2.814e-86	296.0	COG1520@1|root,COG1520@2|Bacteria,2IX03@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_5482185_3	452637.Oter_0071	2.023e-227	739.0	COG3127@1|root,COG3127@2|Bacteria,46UKQ@74201|Verrucomicrobia,3K7U2@414999|Opitutae	414999|Opitutae	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_5482185_12	518766.Rmar_0541	1.997e-95	322.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1FJY7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5482185_15	518766.Rmar_0540	3.923e-64	228.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1FJCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
ZZS2_k127_5482185_19	930169.B5T_00157	2.526e-40	174.0	COG4188@1|root,COG4188@2|Bacteria,1Q4K6@1224|Proteobacteria,1S7GC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5482185_18	485913.Krac_5424	2.616e-43	163.0	COG1881@1|root,COG1881@2|Bacteria,2G6ZP@200795|Chloroflexi	200795|Chloroflexi	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
ZZS2_k127_5482185_14	1403819.BATR01000132_gene4686	8.671e-73	246.0	COG3795@1|root,COG3795@2|Bacteria,46V6E@74201|Verrucomicrobia,2IVM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_5482185_11	1403819.BATR01000146_gene5003	1.593e-97	323.0	COG4941@1|root,COG4941@2|Bacteria,46TPI@74201|Verrucomicrobia,2IV2U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5482185_5	1123508.JH636440_gene2836	2.504e-209	659.0	COG4102@1|root,COG4102@2|Bacteria,2IXKP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5482185_1	344747.PM8797T_24646	8.602e-306	970.0	COG2010@1|root,COG2010@2|Bacteria,2IY1J@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_5482185_21	1283287.KB822588_gene1157	7.501e-05	53.0	COG3087@1|root,COG3211@1|root,COG3087@2|Bacteria,COG3211@2|Bacteria	2|Bacteria	O	Phosphatase	phoX	-	-	ko:K01932,ko:K03531,ko:K03980,ko:K07093	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01011,ko02000,ko02048,ko03036,ko04812	2.A.66.4	-	-	DUF839,SPOR
ZZS2_k127_5482185_2	497964.CfE428DRAFT_5642	6.364e-248	771.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5482185_16	1121957.ATVL01000006_gene2934	1.634e-61	227.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	phoA	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos,PQQ_2,PQQ_3
ZZS2_k127_5482185_9	616991.JPOO01000003_gene1313	1.036e-154	499.0	COG3356@1|root,COG3356@2|Bacteria,4NHGJ@976|Bacteroidetes,1I88B@117743|Flavobacteriia,23GP6@178469|Arenibacter	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5482185_10	497964.CfE428DRAFT_6005	2.93e-142	457.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_5482185_13	497964.CfE428DRAFT_3500	1.607e-90	327.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.4,3.2.1.78	ko:K01179,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH26,GH5,GH9	-	CBM_2,DUF4849,Glyco_hydro_18
ZZS2_k127_5482185_8	1123508.JH636447_gene7858	7.546e-155	517.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5482185_17	404380.Gbem_1914	2.723e-55	203.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,42QPI@68525|delta/epsilon subdivisions,2WMUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
ZZS2_k127_5482185_0	886293.Sinac_1153	0.0	1100.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
ZZS2_k127_5482185_4	886293.Sinac_1154	2.93e-223	698.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_5482185_6	886293.Sinac_1155	6.079e-186	597.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
ZZS2_k127_5482185_7	497964.CfE428DRAFT_1249	3.283e-161	523.0	COG3866@1|root,COG3866@2|Bacteria,46SQX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_54824_4	313628.LNTAR_20703	6.215e-42	173.0	COG3147@1|root,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DUF3108,SPOR
ZZS2_k127_54824_9	1142394.PSMK_15650	9.647e-13	81.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
ZZS2_k127_54824_2	313628.LNTAR_12676	1.71e-107	365.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_54824_0	313628.LNTAR_12671	2.904e-176	574.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
ZZS2_k127_54824_7	754476.Q7A_2284	3.463e-21	106.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
ZZS2_k127_54824_6	1380394.JADL01000002_gene1390	9.219e-25	115.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2JQ8K@204441|Rhodospirillales	204441|Rhodospirillales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
ZZS2_k127_54824_8	1079460.ATTQ01000052_gene6362	1.162e-18	101.0	COG0330@1|root,COG0330@2|Bacteria,1R3PY@1224|Proteobacteria,2UPJ3@28211|Alphaproteobacteria,4B84N@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_54824_5	313628.LNTAR_13872	1.573e-29	130.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
ZZS2_k127_54824_3	118163.Ple7327_2631	2.987e-67	240.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,3VI6T@52604|Pleurocapsales	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
ZZS2_k127_54824_1	756272.Plabr_1000	1.742e-169	544.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
ZZS2_k127_54824_10	1170562.Cal6303_4120	3.861e-08	56.0	COG0457@1|root,COG0457@2|Bacteria,1GE9K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
ZZS2_k127_5499470_4	1121403.AUCV01000081_gene3762	1.858e-06	51.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42TZ6@68525|delta/epsilon subdivisions,2WQY3@28221|Deltaproteobacteria,2MN04@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
ZZS2_k127_5499470_2	102232.GLO73106DRAFT_00016540	3.15e-29	137.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	yvnB	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	LTD,Metallophos,PAP2,VCBS
ZZS2_k127_5499470_3	575540.Isop_1177	1.746e-20	108.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
ZZS2_k127_5499470_1	588596.U9TQM8	3.38e-45	190.0	2BZIK@1|root,2S2JT@2759|Eukaryota,39KT3@33154|Opisthokonta,3P2P9@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_5499470_0	1396141.BATP01000060_gene4563	4.04e-63	237.0	COG0457@1|root,COG0457@2|Bacteria,46W3Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
ZZS2_k127_5500071_4	234267.Acid_2307	3.204e-73	260.0	COG0577@1|root,COG0577@2|Bacteria,3Y6XU@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_5500071_6	278963.ATWD01000001_gene3285	2.452e-37	143.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
ZZS2_k127_5500071_1	497964.CfE428DRAFT_3055	3.206e-163	519.0	COG1494@1|root,COG1494@2|Bacteria,46THC@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	-	-	-	-	-	-	-	-	-	-	FBPase_glpX
ZZS2_k127_5500071_14	1396141.BATP01000034_gene4198	1.154e-13	87.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_5500071_11	794903.OPIT5_23595	1.544e-21	113.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	I-set,Ig_3,PQQ_2
ZZS2_k127_5500071_0	1396141.BATP01000003_gene4934	1.079e-179	624.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_5500071_3	497964.CfE428DRAFT_0545	5.385e-78	267.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5500071_2	1396141.BATP01000021_gene180	7.807e-105	372.0	COG0515@1|root,COG0515@2|Bacteria	1396141.BATP01000021_gene180|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5500071_5	1396141.BATP01000047_gene3904	5.636e-50	194.0	COG1680@1|root,COG1680@2|Bacteria,46SEQ@74201|Verrucomicrobia,2IU3U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_5500071_10	485913.Krac_2537	1.118e-21	98.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
ZZS2_k127_5500071_12	1396141.BATP01000034_gene4210	3.777e-19	99.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
ZZS2_k127_5500071_8	1396141.BATP01000022_gene335	2.772e-24	119.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5500071_13	318161.Sden_1409	3.722e-14	88.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2Q8YZ@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,PPC,P_proprotein,Peptidase_S8
ZZS2_k127_5500071_9	243090.RB1661	1.782e-23	119.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PA14,Pentaxin,Peptidase_S74
ZZS2_k127_5500071_7	1173026.Glo7428_3606	9.066e-31	143.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
ZZS2_k127_5505476_4	1403819.BATR01000096_gene3165	4.722e-112	373.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3356@1|root,COG4625@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3356@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_C,HEAT_2,Laminin_G_3,ThuA
ZZS2_k127_5505476_3	886293.Sinac_4605	5.608e-114	381.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
ZZS2_k127_5505476_5	1499967.BAYZ01000147_gene711	1.29e-34	148.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_5505476_2	497964.CfE428DRAFT_6439	6.011e-121	397.0	COG0413@1|root,COG0413@2|Bacteria	2|Bacteria	H	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	-	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
ZZS2_k127_5505476_7	521674.Plim_3206	4.038e-06	52.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
ZZS2_k127_5505476_0	344747.PM8797T_04335	1.882e-185	595.0	COG3119@1|root,COG3119@2|Bacteria,2J2Z5@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
ZZS2_k127_5505476_1	1396418.BATQ01000035_gene5727	4.305e-154	498.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS2_k127_5505476_6	62928.azo3264	3.653e-08	64.0	2DBVG@1|root,2ZBB1@2|Bacteria,1N1MS@1224|Proteobacteria,2VPUQ@28216|Betaproteobacteria,2KYCG@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5505476_8	1122182.KB903813_gene2572	9.597e-06	57.0	COG3896@1|root,COG3896@2|Bacteria,2IFF0@201174|Actinobacteria,4DE7I@85008|Micromonosporales	201174|Actinobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
ZZS2_k127_5512641_1	1501230.ET33_05640	5.205e-60	215.0	COG4859@1|root,COG4859@2|Bacteria,1V685@1239|Firmicutes,4IQV5@91061|Bacilli,276J1@186822|Paenibacillaceae	91061|Bacilli	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
ZZS2_k127_5512641_0	452637.Oter_0306	8.614e-70	246.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064,Glycos_transf_2
ZZS2_k127_5512641_2	452637.Oter_0296	1.452e-54	202.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K16648,ko:K20444	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glycos_transf_2,Methyltransf_11,NTP_transf_5
ZZS2_k127_5526156_15	1396141.BATP01000060_gene4708	2.335e-17	83.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia,2IUN6@203494|Verrucomicrobiae	2|Bacteria	K	ECF sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
ZZS2_k127_5526156_19	452637.Oter_2424	4.266e-09	64.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_5526156_17	886293.Sinac_5445	1.457e-11	71.0	COG0515@1|root,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8,WD40
ZZS2_k127_5526156_11	497964.CfE428DRAFT_0187	7.521e-21	108.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
ZZS2_k127_5526156_5	497964.CfE428DRAFT_1861	1.117e-71	272.0	COG1595@1|root,COG4194@1|root,COG1595@2|Bacteria,COG4194@2|Bacteria,46TQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_5526156_6	886293.Sinac_3442	1.953e-60	237.0	COG0526@1|root,COG1470@1|root,COG1595@1|root,COG0526@2|Bacteria,COG1470@2|Bacteria,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	AhpC-TSA,DUF4384,NPCBM_assoc,PEGA,Sigma70_r2,Sigma70_r4_2,Thioredoxin_8
ZZS2_k127_5526156_22	1123261.AXDW01000007_gene2127	6.262e-06	58.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,1S9ZY@1236|Gammaproteobacteria,1X4DZ@135614|Xanthomonadales	135614|Xanthomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS2_k127_5526156_3	1396141.BATP01000039_gene1469	8.402e-86	312.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_5526156_20	478741.JAFS01000001_gene1765	1.819e-08	63.0	2CP7W@1|root,32SIM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5526156_2	1163617.SCD_n02152	9.556e-105	349.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
ZZS2_k127_5526156_8	794903.OPIT5_06500	2.587e-31	127.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
ZZS2_k127_5526156_4	1396141.BATP01000003_gene5267	2.597e-76	258.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
ZZS2_k127_5526156_9	379731.PST_0238	3.552e-29	119.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria,1Z478@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
ZZS2_k127_5526156_1	530564.Psta_1209	1.509e-206	658.0	COG0003@1|root,COG0003@2|Bacteria,2IY37@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM arsenite-activated ATPase (arsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
ZZS2_k127_5526156_14	481448.Minf_1084	1.758e-17	87.0	COG2331@1|root,COG2331@2|Bacteria,46T5Z@74201|Verrucomicrobia,37H04@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5526156_21	314230.DSM3645_18701	4.196e-06	52.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_5526156_12	234267.Acid_7571	4.347e-20	92.0	COG0823@1|root,COG0823@2|Bacteria,3Y95P@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_5526156_7	102125.Xen7305DRAFT_00027950	8.597e-37	143.0	2F563@1|root,33XSZ@2|Bacteria,1GDX8@1117|Cyanobacteria	102125.Xen7305DRAFT_00027950|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5526156_10	102125.Xen7305DRAFT_00048520	1.431e-23	106.0	2F900@1|root,341BR@2|Bacteria,1GEHQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5526156_13	633.DJ40_3220	3.55e-19	91.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,1S4Y0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS2_k127_5526156_0	316067.Geob_1292	0.0	1060.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42SMD@68525|delta/epsilon subdivisions,2WPCI@28221|Deltaproteobacteria,43U6S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
ZZS2_k127_5526156_18	264198.Reut_A2884	2.128e-11	65.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2VH3E@28216|Betaproteobacteria,1K2TP@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
ZZS2_k127_5528180_0	240016.ABIZ01000001_gene4547	6.637e-181	583.0	COG1262@1|root,COG2010@1|root,COG1262@2|Bacteria,COG2010@2|Bacteria,46UX3@74201|Verrucomicrobia,2ITQQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PSCyt1
ZZS2_k127_5528180_4	1123070.KB899253_gene1115	5.012e-86	295.0	COG0331@1|root,COG0331@2|Bacteria,46SNS@74201|Verrucomicrobia,2ITTM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
ZZS2_k127_5528180_5	1396418.BATQ01000067_gene1728	1.841e-85	289.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2ITSE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_5528180_6	478741.JAFS01000001_gene1181	8.269e-31	122.0	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia,37GVN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS2_k127_5528180_1	349741.Amuc_1327	7.884e-170	542.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS2_k127_5528180_3	404589.Anae109_0662	2.008e-108	366.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
ZZS2_k127_5528180_2	1340493.JNIF01000003_gene1832	3.59e-128	417.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
ZZS2_k127_5528915_0	765420.OSCT_3130	1.284e-58	219.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
ZZS2_k127_5531636_7	1173023.KE650771_gene530	7.392e-12	66.0	2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS2_k127_5531636_0	1232437.KL662047_gene5205	8.074e-75	263.0	COG1073@1|root,COG1073@2|Bacteria,1NEVB@1224|Proteobacteria,42W4K@68525|delta/epsilon subdivisions,2WRSK@28221|Deltaproteobacteria,2MN89@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5531636_8	204669.Acid345_4517	6.581e-08	65.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS2_k127_5531636_5	1370121.AUWS01000009_gene5806	1.516e-24	113.0	COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,233F1@1762|Mycobacteriaceae	201174|Actinobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NIL
ZZS2_k127_5531636_3	330214.NIDE1503	4.897e-31	133.0	COG0767@1|root,COG0767@2|Bacteria,3J0P4@40117|Nitrospirae	40117|Nitrospirae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS2_k127_5531636_1	1121897.AUGO01000002_gene2177	1.251e-69	264.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_5531636_2	1396418.BATQ01000160_gene4912	3.556e-49	191.0	COG3547@1|root,COG3547@2|Bacteria,46WNP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
ZZS2_k127_5531636_4	261292.Nit79A3_1073	2.369e-28	133.0	COG0652@1|root,COG0652@2|Bacteria,1RCXX@1224|Proteobacteria,2WD5W@28216|Betaproteobacteria,373YC@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Peptidyl-prolyl cis-trans isomerase, cyclophilin-type	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
ZZS2_k127_5531636_6	28444.JODQ01000018_gene7284	2.71e-14	85.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
ZZS2_k127_5531636_9	926550.CLDAP_19490	6.532e-07	61.0	COG1319@1|root,COG2931@1|root,COG3420@1|root,COG1319@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FAD_binding_5
ZZS2_k127_5535206_5	530564.Psta_1454	4.71e-134	433.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
ZZS2_k127_5535206_13	411476.BACOVA_03088	2.886e-14	77.0	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,2FMB1@200643|Bacteroidia,4AMRE@815|Bacteroidaceae	976|Bacteroidetes	G	pectate lyase	pelA	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pec_lyase,Pectinesterase
ZZS2_k127_5535206_9	1210884.HG799462_gene7797	8.176e-45	168.0	COG1051@1|root,COG1051@2|Bacteria,2J0WI@203682|Planctomycetes	203682|Planctomycetes	F	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
ZZS2_k127_5535206_1	497964.CfE428DRAFT_6083	7.302e-284	888.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
ZZS2_k127_5535206_8	1123508.JH636440_gene2248	2.082e-45	168.0	2E1Y1@1|root,32X6X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5535206_3	379066.GAU_1229	1.27e-231	736.0	COG1028@1|root,COG1028@2|Bacteria,1ZT0F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS2_k127_5535206_0	794903.OPIT5_26110	0.0	1110.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,3K75C@414999|Opitutae	414999|Opitutae	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
ZZS2_k127_5535206_7	240016.ABIZ01000001_gene5099	1.05e-91	304.0	COG0110@1|root,COG0110@2|Bacteria,46TEB@74201|Verrucomicrobia,2IUHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Mac
ZZS2_k127_5535206_2	1403819.BATR01000009_gene302	1.474e-251	784.0	COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia,2IVET@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS2_k127_5535206_12	247639.MGP2080_02111	7.2e-31	131.0	COG2067@1|root,COG2067@2|Bacteria,1NDQA@1224|Proteobacteria,1TIWZ@1236|Gammaproteobacteria,1JBA2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5535206_6	234267.Acid_5820	3.559e-93	327.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
ZZS2_k127_5535206_4	234267.Acid_5819	9.49e-159	523.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
ZZS2_k127_5535206_10	682795.AciX8_1324	1.448e-37	160.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria,2JI17@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5535206_11	316274.Haur_1682	6.027e-37	160.0	COG5267@1|root,COG5267@2|Bacteria,2G7Q0@200795|Chloroflexi,376N0@32061|Chloroflexia	2|Bacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_557366_0	240016.ABIZ01000001_gene2256	8.617e-273	887.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
ZZS2_k127_557366_2	717605.Theco_1040	1.931e-25	113.0	COG0128@1|root,COG0128@2|Bacteria,1VK19@1239|Firmicutes,4HQZ9@91061|Bacilli,26WZM@186822|Paenibacillaceae	91061|Bacilli	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_557366_1	1123242.JH636434_gene3357	7.85e-181	578.0	COG0277@1|root,COG0277@2|Bacteria,2IXH8@203682|Planctomycetes	203682|Planctomycetes	C	Glycolate oxidase subunit	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS2_k127_5573806_4	56110.Oscil6304_4756	3.323e-120	403.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,1GDJY@1117|Cyanobacteria,1H8JX@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_5573806_5	269799.Gmet_2821	7.134e-106	366.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,43UJ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NmrA-like family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
ZZS2_k127_5573806_20	278957.ABEA03000206_gene3778	1.06e-18	92.0	COG0457@1|root,COG0457@2|Bacteria,46Z69@74201|Verrucomicrobia,3K8AP@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5573806_0	1123242.JH636435_gene1245	0.0	1054.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
ZZS2_k127_5573806_7	521674.Plim_2581	2.856e-101	338.0	COG0708@1|root,COG0708@2|Bacteria,2J3Z5@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_5573806_18	497964.CfE428DRAFT_6522	4.277e-49	186.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
ZZS2_k127_5573806_16	760568.Desku_1636	9.666e-55	206.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,261SM@186807|Peptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02525,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
ZZS2_k127_5573806_17	518766.Rmar_1525	9.876e-55	202.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1FIPR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
ZZS2_k127_5573806_10	1123371.ATXH01000012_gene1416	4.925e-74	257.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
ZZS2_k127_5573806_22	497964.CfE428DRAFT_5639	2.645e-10	68.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_5639|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5573806_2	56780.SYN_00126	3.821e-152	490.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_5573806_3	1304888.ATWF01000001_gene1852	1.203e-131	429.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_5573806_13	478741.JAFS01000001_gene1269	7.781e-59	219.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,37GK5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
ZZS2_k127_5573806_21	1396141.BATP01000003_gene5038	1.405e-10	67.0	29N11@1|root,344HT@2|Bacteria,46WBB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5573806_6	794903.OPIT5_17010	9.331e-103	350.0	COG0144@1|root,COG0144@2|Bacteria,46YF5@74201|Verrucomicrobia,3K75D@414999|Opitutae	414999|Opitutae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
ZZS2_k127_5573806_15	1142394.PSMK_14730	2.212e-55	203.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
ZZS2_k127_5573806_8	497964.CfE428DRAFT_4175	1.021e-89	304.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5573806_19	1142394.PSMK_16020	3.578e-25	113.0	COG4968@1|root,COG4968@2|Bacteria,2IY7F@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_5573806_12	768706.Desor_5329	4.513e-65	243.0	COG0726@1|root,COG0726@2|Bacteria,1VI89@1239|Firmicutes,24F3G@186801|Clostridia,266MA@186807|Peptococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5573806_9	1121272.KB903253_gene6883	3.66e-87	299.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DCYX@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_5573806_11	172088.AUGA01000008_gene970	1.885e-68	235.0	COG1045@1|root,COG1045@2|Bacteria,1QWJD@1224|Proteobacteria,2TWZD@28211|Alphaproteobacteria,3JYB2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
ZZS2_k127_5573806_1	1509405.GV67_19495	3.018e-162	517.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,4BA1X@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_5573806_14	335543.Sfum_0963	1.883e-57	208.0	COG3307@1|root,COG3307@2|Bacteria,1Q4PM@1224|Proteobacteria,42ZKE@68525|delta/epsilon subdivisions,2WUZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_5577882_2	344747.PM8797T_00337	1.025e-191	625.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
ZZS2_k127_5577882_16	1396418.BATQ01000163_gene1977	4.66e-51	196.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
ZZS2_k127_5577882_7	382464.ABSI01000002_gene4290	2.178e-112	401.0	COG0457@1|root,COG0457@2|Bacteria,46X09@74201|Verrucomicrobia,2IW9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_2,TPR_7,TPR_8
ZZS2_k127_5577882_5	382464.ABSI01000002_gene4289	4.155e-118	406.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	prsK	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c
ZZS2_k127_5577882_3	382464.ABSI01000002_gene4287	7.398e-166	533.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	2|Bacteria	T	Bacterial regulatory protein, Fis family	atoC	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_5577882_1	583355.Caka_2778	1.076e-215	734.0	COG3334@1|root,COG3334@2|Bacteria	2|Bacteria	S	PFAM MgtE intracellular	ylxF	-	-	ko:K02383	-	-	-	-	ko00000,ko02035	-	-	-	MgtE_N
ZZS2_k127_5577882_0	497964.CfE428DRAFT_1508	2.381e-228	722.0	COG1620@1|root,COG1620@2|Bacteria,46UQW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
ZZS2_k127_5577882_20	404589.Anae109_1180	4.563e-23	102.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
ZZS2_k127_5577882_21	1120949.KB903317_gene1643	9.641e-21	106.0	COG2133@1|root,COG3291@1|root,COG3506@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,2HEMB@201174|Actinobacteria,4DA70@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PA14,PKD
ZZS2_k127_5577882_17	497964.CfE428DRAFT_1664	2.665e-38	152.0	COG1985@1|root,COG1985@2|Bacteria,46WC6@74201|Verrucomicrobia	74201|Verrucomicrobia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS2_k127_5577882_10	1444309.JAQG01000035_gene2140	4.421e-102	344.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,26RP1@186822|Paenibacillaceae	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
ZZS2_k127_5577882_22	478741.JAFS01000001_gene1123	1.112e-16	85.0	COG2001@1|root,COG2001@2|Bacteria,46T5G@74201|Verrucomicrobia,37GRY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
ZZS2_k127_5577882_14	324602.Caur_0763	2.661e-69	246.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,374SY@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
ZZS2_k127_5577882_8	583355.Caka_3065	7.698e-104	364.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
ZZS2_k127_5577882_4	497964.CfE428DRAFT_2939	2.258e-145	477.0	COG0768@1|root,COG0769@1|root,COG0768@2|Bacteria,COG0769@2|Bacteria,46SGG@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_5577882_12	497964.CfE428DRAFT_2938	1.046e-91	324.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_5577882_9	497964.CfE428DRAFT_2937	2.123e-102	346.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
ZZS2_k127_5577882_11	1382359.JIAL01000001_gene1975	8.281e-93	321.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_5577882_23	1304872.JAGC01000003_gene2595	2.19e-12	77.0	COG1388@1|root,COG2845@1|root,COG1388@2|Bacteria,COG2845@2|Bacteria,1R14S@1224|Proteobacteria,43D67@68525|delta/epsilon subdivisions,2X69A@28221|Deltaproteobacteria,2M9WA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF459,LysM
ZZS2_k127_5577882_13	373903.Hore_09080	3.307e-72	258.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WAGK@53433|Halanaerobiales	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
ZZS2_k127_5577882_15	478741.JAFS01000001_gene1132	4.884e-68	246.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia,37GBU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
ZZS2_k127_5577882_19	760568.Desku_1156	1.656e-32	132.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,260QE@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_557920_2	261292.Nit79A3_1492	5.794e-12	68.0	COG1787@1|root,COG1787@2|Bacteria,1NEPX@1224|Proteobacteria	1224|Proteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_557920_0	886293.Sinac_3442	1.657e-51	209.0	COG0526@1|root,COG1470@1|root,COG1595@1|root,COG0526@2|Bacteria,COG1470@2|Bacteria,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	AhpC-TSA,DUF4384,NPCBM_assoc,PEGA,Sigma70_r2,Sigma70_r4_2,Thioredoxin_8
ZZS2_k127_557920_1	926550.CLDAP_27370	7.437e-40	171.0	COG1520@1|root,COG1520@2|Bacteria,2G945@200795|Chloroflexi	200795|Chloroflexi	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5594810_0	497964.CfE428DRAFT_4579	9.347e-95	316.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ZZS2_k127_5594810_1	1232410.KI421419_gene2479	3.742e-37	151.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,43S9I@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
ZZS2_k127_56071_9	497964.CfE428DRAFT_1860	8.401e-104	347.0	COG3464@1|root,COG3464@2|Bacteria,46VFX@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
ZZS2_k127_56071_0	497964.CfE428DRAFT_2769	2.089e-235	733.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_56071_1	497964.CfE428DRAFT_2769	2.403e-221	692.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_56071_3	497964.CfE428DRAFT_2769	1.019e-190	606.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_56071_31	452637.Oter_0649	9.075e-05	51.0	299RH@1|root,2ZWTR@2|Bacteria,46WTD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_56071_32	926690.KE386573_gene2348	0.0003914	53.0	arCOG02911@1|root,arCOG02911@2157|Archaea,2XUPG@28890|Euryarchaeota,23TEP@183963|Halobacteria	183963|Halobacteria	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_56071_4	1396418.BATQ01000053_gene34	6.225e-173	556.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,2ITHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
ZZS2_k127_56071_15	1403819.BATR01000029_gene948	1.776e-71	251.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
ZZS2_k127_56071_12	66897.DJ64_23235	1.182e-93	317.0	COG1090@1|root,COG1090@2|Bacteria,2GU34@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
ZZS2_k127_56071_16	314230.DSM3645_08872	2.598e-71	248.0	COG3361@1|root,COG3361@2|Bacteria,2IYZC@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
ZZS2_k127_56071_26	1403819.BATR01000030_gene952	2.056e-16	84.0	2DS4P@1|root,33EH8@2|Bacteria,46XKS@74201|Verrucomicrobia,2IW5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_56071_21	314230.DSM3645_07370	6.822e-54	206.0	295WE@1|root,2ZT7B@2|Bacteria,2J2RS@203682|Planctomycetes	203682|Planctomycetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
ZZS2_k127_56071_18	1120999.JONM01000003_gene2723	2.265e-66	231.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
ZZS2_k127_56071_17	497964.CfE428DRAFT_1049	2.116e-70	241.0	COG3837@1|root,COG3837@2|Bacteria,46T0V@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_56071_20	382464.ABSI01000013_gene1727	1.482e-55	204.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia	74201|Verrucomicrobia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
ZZS2_k127_56071_7	497964.CfE428DRAFT_0769	2.393e-111	379.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_56071_24	1396141.BATP01000023_gene577	3.695e-24	111.0	COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
ZZS2_k127_56071_25	794903.OPIT5_13005	4.217e-19	97.0	COG2165@1|root,COG2165@2|Bacteria,46Z5T@74201|Verrucomicrobia,3K9RI@414999|Opitutae	414999|Opitutae	U	Protein of unknown function (DUF1559)	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
ZZS2_k127_56071_11	497964.CfE428DRAFT_6600	1.253e-96	321.0	COG0410@1|root,COG0410@2|Bacteria,46SJB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS2_k127_56071_10	452637.Oter_2014	1.956e-99	331.0	COG0411@1|root,COG0411@2|Bacteria	2|Bacteria	E	ABC transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS2_k127_56071_8	452637.Oter_2016	4.811e-111	374.0	COG4177@1|root,COG4177@2|Bacteria,46TPN@74201|Verrucomicrobia,3K8WU@414999|Opitutae	414999|Opitutae	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS2_k127_56071_6	1396141.BATP01000057_gene3028	1.106e-138	446.0	COG0559@1|root,COG0559@2|Bacteria,46UCA@74201|Verrucomicrobia,2IVC6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
ZZS2_k127_56071_5	497964.CfE428DRAFT_6596	6.167e-171	545.0	COG0683@1|root,COG0683@2|Bacteria,46UD1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS2_k127_56071_13	497964.CfE428DRAFT_0219	1.115e-82	287.0	COG0583@1|root,COG0583@2|Bacteria,46SM6@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_56071_23	452637.Oter_3494	1.581e-26	111.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,3K8AH@414999|Opitutae	414999|Opitutae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
ZZS2_k127_56071_2	497964.CfE428DRAFT_1010	3.077e-198	627.0	COG0277@1|root,COG0277@2|Bacteria,46S85@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS2_k127_56071_14	497964.CfE428DRAFT_4161	7.835e-79	273.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
ZZS2_k127_56071_22	382464.ABSI01000012_gene2078	3.121e-50	186.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,2IU9Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Guanylate kinase homologues.	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
ZZS2_k127_56071_19	240016.ABIZ01000001_gene2279	4.223e-63	222.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,2IUB8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ZZS2_k127_56071_27	1396141.BATP01000020_gene123	1.739e-13	85.0	COG2982@1|root,COG2982@2|Bacteria,46SSM@74201|Verrucomicrobia,2IUJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
ZZS2_k127_5628538_10	452637.Oter_2155	1.699e-124	403.0	COG2373@1|root,COG2373@2|Bacteria,46U24@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
ZZS2_k127_5628538_3	1396141.BATP01000025_gene935	4.249e-192	634.0	COG0654@1|root,COG3210@1|root,COG0654@2|Bacteria,COG3210@2|Bacteria,46Z4S@74201|Verrucomicrobia,2IVG3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
ZZS2_k127_5628538_12	293826.Amet_3675	6.909e-115	378.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,36EIX@31979|Clostridiaceae	186801|Clostridia	G	Aldolase	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
ZZS2_k127_5628538_19	869210.Marky_0765	9.477e-35	150.0	COG4886@1|root,COG4886@2|Bacteria,1WNAX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Leucine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5628538_0	497964.CfE428DRAFT_4421	1.966e-321	1022.0	COG2319@1|root,COG2319@2|Bacteria,46URD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
ZZS2_k127_5628538_17	1297742.A176_06772	4.071e-54	199.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,434AF@68525|delta/epsilon subdivisions,2X23S@28221|Deltaproteobacteria,2YVSR@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
ZZS2_k127_5628538_4	240016.ABIZ01000001_gene3841	3.575e-184	586.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_5628538_9	497964.CfE428DRAFT_1804	2.113e-137	475.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
ZZS2_k127_5628538_16	1396141.BATP01000029_gene2233	9.834e-62	218.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_5628538_21	215803.DB30_6753	2.523e-28	124.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
ZZS2_k127_5628538_5	497964.CfE428DRAFT_5481	5.8e-176	566.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
ZZS2_k127_5628538_22	1125863.JAFN01000001_gene1525	9.477e-24	114.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
ZZS2_k127_5628538_15	986075.CathTA2_1006	2.425e-72	250.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,4HA3C@91061|Bacilli	91061|Bacilli	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
ZZS2_k127_5628538_23	497964.CfE428DRAFT_1031	1.602e-15	89.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5628538_6	497964.CfE428DRAFT_3605	2.243e-168	544.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
ZZS2_k127_5628538_1	1396418.BATQ01000056_gene159	1.85e-296	933.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TQ1@74201|Verrucomicrobia,2IWNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_5628538_14	1444711.CCJF01000005_gene546	2.028e-87	315.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
ZZS2_k127_5628538_18	404589.Anae109_1654	8.605e-54	200.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,2Z0UJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
ZZS2_k127_5628538_11	887898.HMPREF0551_1070	4.719e-116	405.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2VJDX@28216|Betaproteobacteria,1K1PQ@119060|Burkholderiaceae	28216|Betaproteobacteria	G	trehalohydrolase	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
ZZS2_k127_5628538_2	234267.Acid_4010	3.193e-210	666.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
ZZS2_k127_5628538_7	1396418.BATQ01000078_gene594	4.618e-167	533.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_5628538_8	240016.ABIZ01000001_gene3548	1.889e-158	510.0	COG0577@1|root,COG0577@2|Bacteria,46UT6@74201|Verrucomicrobia,2IVGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_5628538_13	452637.Oter_1514	7.222e-113	369.0	COG1136@1|root,COG1136@2|Bacteria,46YZ8@74201|Verrucomicrobia,3K9FX@414999|Opitutae	414999|Opitutae	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5628538_20	452637.Oter_1515	1.2e-32	130.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
ZZS2_k127_5641060_1	1396141.BATP01000060_gene4707	3.686e-231	752.0	COG0515@1|root,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
ZZS2_k127_5641060_6	1396141.BATP01000060_gene4708	3.545e-65	230.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia,2IUN6@203494|Verrucomicrobiae	2|Bacteria	K	ECF sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
ZZS2_k127_5641060_2	1337936.IJ00_10975	7.618e-158	499.0	COG2267@1|root,COG2267@2|Bacteria,1G000@1117|Cyanobacteria,1HQSB@1161|Nostocales	1117|Cyanobacteria	I	Prolyl oligopeptidase family	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
ZZS2_k127_5641060_7	296591.Bpro_2359	2.338e-63	222.0	29PI0@1|root,30AG5@2|Bacteria,1RE5S@1224|Proteobacteria,2VSJR@28216|Betaproteobacteria,4AG4S@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5641060_5	536019.Mesop_2361	2.626e-104	344.0	COG2267@1|root,COG2267@2|Bacteria,1QU4T@1224|Proteobacteria,2TTC1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS2_k127_5641060_4	240016.ABIZ01000001_gene648	1.441e-117	393.0	COG0845@1|root,COG0845@2|Bacteria,46UG5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
ZZS2_k127_5641060_0	1403819.BATR01000128_gene4555	0.0	1353.0	COG0841@1|root,COG0841@2|Bacteria,46U0U@74201|Verrucomicrobia,2ITVP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_5641060_3	335543.Sfum_1456	5.099e-140	461.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MQ56@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
ZZS2_k127_5641060_8	1173023.KE650771_gene527	3.581e-43	173.0	2AQRE@1|root,31FZ6@2|Bacteria,1G7D6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5641060_10	1245469.S58_60140	9.516e-05	52.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
ZZS2_k127_5641060_9	272630.MexAM1_META1p1525	2.805e-07	57.0	COG3012@1|root,COG3012@2|Bacteria,1RKZA@1224|Proteobacteria,2UA4E@28211|Alphaproteobacteria,1JSBM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM SEC-C motif domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1186,SEC-C
ZZS2_k127_5650083_3	794903.OPIT5_28135	5.108e-51	210.0	29WZ4@1|root,30IMB@2|Bacteria,46U22@74201|Verrucomicrobia,3K7HN@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5650083_1	177437.HRM2_15340	5.97e-105	353.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria,2MKKB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
ZZS2_k127_5650083_6	278957.ABEA03000072_gene3021	8.438e-10	61.0	COG0828@1|root,COG0828@2|Bacteria,46WBR@74201|Verrucomicrobia,3K8F7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ZZS2_k127_5650083_4	478741.JAFS01000002_gene891	7.274e-44	168.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,37GQD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
ZZS2_k127_5650083_5	452637.Oter_4551	1.381e-42	164.0	COG0290@1|root,COG0290@2|Bacteria,46V47@74201|Verrucomicrobia,3K841@414999|Opitutae	414999|Opitutae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
ZZS2_k127_5650083_2	497964.CfE428DRAFT_2095	1.845e-54	198.0	COG3832@1|root,COG3832@2|Bacteria,46VGW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
ZZS2_k127_5650083_0	1210884.HG799464_gene10778	2.005e-131	430.0	COG2382@1|root,COG2382@2|Bacteria,2J219@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_5650083_7	1379698.RBG1_1C00001G1438	2.636e-06	53.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
ZZS2_k127_566672_7	595460.RRSWK_02469	8.742e-37	141.0	COG0719@1|root,COG0719@2|Bacteria,2IY25@203682|Planctomycetes	203682|Planctomycetes	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
ZZS2_k127_566672_6	269796.Rru_A3475	3.404e-44	167.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,2JT4T@204441|Rhodospirillales	204441|Rhodospirillales	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
ZZS2_k127_566672_3	1437824.BN940_09076	2.809e-58	207.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VPN0@28216|Betaproteobacteria,3T3HF@506|Alcaligenaceae	28216|Betaproteobacteria	S	Iron-sulfur cluster assembly protein	sufT	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
ZZS2_k127_566672_0	1396418.BATQ01000079_gene806	2.185e-158	509.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
ZZS2_k127_566672_8	240016.ABIZ01000001_gene3027	6.188e-26	125.0	2EHVJ@1|root,33BM3@2|Bacteria,46XIU@74201|Verrucomicrobia,2IW14@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_566672_9	160799.PBOR_16515	1.316e-24	121.0	COG0457@1|root,COG0457@2|Bacteria,1VDZT@1239|Firmicutes,4HX3R@91061|Bacilli,26Z1E@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_566672_4	1396418.BATQ01000140_gene3197	1.951e-54	197.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia,2IUCJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_566672_5	497964.CfE428DRAFT_0260	8.303e-49	179.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
ZZS2_k127_566672_2	497964.CfE428DRAFT_1841	1.479e-118	389.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_566672_12	926560.KE387023_gene1413	0.0002597	55.0	COG3693@1|root,COG3828@1|root,COG3693@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_2,CBM_3,CBM_4_9,CBM_6,Glyco_hydro_10,Glyco_hydro_48,Ricin_B_lectin,VCBS,fn3
ZZS2_k127_566672_11	1122611.KB903957_gene111	1.235e-18	103.0	COG5297@1|root,COG5297@2|Bacteria,2I2T2@201174|Actinobacteria,4ER3X@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolase family 48	celY	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_3,Glyco_hydro_48,fn3
ZZS2_k127_566672_1	1403819.BATR01000185_gene6430	1.567e-122	442.0	COG3121@1|root,COG3204@1|root,COG3291@1|root,COG3506@1|root,COG5184@1|root,COG3121@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_566672_10	886293.Sinac_1477	2.405e-19	92.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5668656_6	903818.KI912268_gene3014	6.851e-25	119.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc
ZZS2_k127_5668656_4	344747.PM8797T_30444	7.202e-41	164.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
ZZS2_k127_5668656_3	661478.OP10G_0095	2.107e-44	181.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671,ko:K07152	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03029,ko03110	-	-	-	AhpC-TSA,Glyco_hydro_8,Redoxin,SCO1-SenC,Thioredoxin,Thioredoxin_8
ZZS2_k127_5668656_5	710686.Mycsm_01149	3.215e-28	118.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria,238ZD@1762|Mycobacteriaceae	201174|Actinobacteria	O	organic hydroperoxide resistance protein	ohr	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS2_k127_5668656_1	886293.Sinac_7220	3.747e-119	407.0	COG0642@1|root,COG2205@2|Bacteria,2IZC4@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_5668656_2	530564.Psta_3872	4.452e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,2IZ9J@203682|Planctomycetes	203682|Planctomycetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_5668656_0	1123508.JH636444_gene5476	3.454e-172	559.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
ZZS2_k127_5668656_8	1396141.BATP01000005_gene6062	3.135e-08	55.0	COG1762@1|root,COG1762@2|Bacteria,46VMP@74201|Verrucomicrobia,2IUWS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
ZZS2_k127_5687147_5	1123242.JH636435_gene788	1.086e-12	70.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_5687147_3	1396141.BATP01000005_gene6072	1.639e-32	137.0	COG0346@1|root,COG0346@2|Bacteria,46XT5@74201|Verrucomicrobia,2IWI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_5687147_4	1123508.JH636440_gene2241	9.624e-25	109.0	2ENPA@1|root,33GAP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5687147_2	1121403.AUCV01000010_gene1383	4.541e-46	178.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
ZZS2_k127_5687147_1	497964.CfE428DRAFT_0869	1.644e-135	443.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
ZZS2_k127_5687147_0	1403819.BATR01000002_gene28	8.055e-160	515.0	COG1253@1|root,COG1253@2|Bacteria,46U7J@74201|Verrucomicrobia,2IVE3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
ZZS2_k127_569408_0	452637.Oter_0960	6.588e-188	599.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	2|Bacteria	T	sigma-54 factor interaction domain-containing protein	-	-	-	ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_569408_2	452637.Oter_0959	3.56e-124	408.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,46UCX@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_569408_1	1396418.BATQ01000056_gene240	1.091e-157	524.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,46UM4@74201|Verrucomicrobia,2IWNI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Response_reg
ZZS2_k127_569408_4	861299.J421_1652	1.991e-66	242.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS2_k127_569408_9	1266925.JHVX01000001_gene2468	1.59e-14	77.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2W8JG@28216|Betaproteobacteria,373T2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_569408_10	1408433.JHXV01000006_gene2669	4.781e-05	50.0	COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,1I57R@117743|Flavobacteriia,2PB84@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
ZZS2_k127_569408_8	794903.OPIT5_29615	1.741e-15	78.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
ZZS2_k127_569408_5	497964.CfE428DRAFT_4864	2.176e-54	200.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_569408_3	886293.Sinac_6489	3.126e-106	371.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_5706385_0	555079.Toce_1592	1.649e-116	385.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,42FND@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM DegT DnrJ EryC1 StrS aminotransferase	degT1	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_5706385_1	768671.ThimaDRAFT_3418	5.656e-76	264.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WXRA@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_5706385_2	497964.CfE428DRAFT_3384	6.85e-28	114.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
ZZS2_k127_5717849_4	446466.Cfla_0383	2.304e-32	146.0	COG2755@1|root,COG2755@2|Bacteria,2GP5V@201174|Actinobacteria	201174|Actinobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
ZZS2_k127_5717849_3	1396418.BATQ01000110_gene4761	1.398e-156	504.0	COG0560@1|root,COG0560@2|Bacteria,46VDQ@74201|Verrucomicrobia,2ITM4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
ZZS2_k127_5717849_2	1210884.HG799462_gene7993	2.318e-197	634.0	COG0457@1|root,COG0457@2|Bacteria,2IZEP@203682|Planctomycetes	1210884.HG799462_gene7993|-	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5717849_0	1123508.JH636439_gene1798	7.37e-258	818.0	COG1506@1|root,COG1506@2|Bacteria,2IY8M@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF885,Peptidase_S9,VHL
ZZS2_k127_5717849_1	234267.Acid_1796	1.15e-206	666.0	COG1501@1|root,COG1501@2|Bacteria,3Y4C8@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177,3.2.1.20	ko:K01187,ko:K01811	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
ZZS2_k127_5726290_13	926554.KI912633_gene3705	5.194e-10	69.0	COG0589@1|root,COG0589@2|Bacteria,1WJW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS2_k127_5726290_4	497964.CfE428DRAFT_3249	4.706e-104	345.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
ZZS2_k127_5726290_10	518766.Rmar_2228	6.398e-39	167.0	COG2203@1|root,COG3829@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
ZZS2_k127_5726290_1	452637.Oter_1548	4.738e-147	493.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,Trans_reg_C
ZZS2_k127_5726290_8	765420.OSCT_2222	1.129e-61	216.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	MA20_29145	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_5726290_6	452637.Oter_1550	7.548e-95	323.0	COG2204@1|root,COG4585@1|root,COG2204@2|Bacteria,COG4585@2|Bacteria,46U87@74201|Verrucomicrobia,3K9VW@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
ZZS2_k127_5726290_7	452637.Oter_1551	8.21e-89	299.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_5726290_12	1227352.C173_02924	5.499e-13	76.0	COG0745@1|root,COG0745@2|Bacteria,1TR0B@1239|Firmicutes,4HB7C@91061|Bacilli,26RNH@186822|Paenibacillaceae	91061|Bacilli	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP1	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_5726290_0	497964.CfE428DRAFT_6200	1.43e-158	505.0	COG1064@1|root,COG1064@2|Bacteria,46UVP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
ZZS2_k127_5726290_9	1144319.PMI16_00017	1.077e-44	173.0	COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria,4778U@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	PFAM Response regulator receiver domain, Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_5726290_11	521098.Aaci_2011	8.507e-30	124.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,278CC@186823|Alicyclobacillaceae	91061|Bacilli	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
ZZS2_k127_5726290_3	794903.OPIT5_07475	1.869e-112	370.0	2C130@1|root,30TQV@2|Bacteria,46XGK@74201|Verrucomicrobia,3K9V7@414999|Opitutae	414999|Opitutae	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
ZZS2_k127_5726290_17	1232437.KL662011_gene1515	0.0006907	48.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2MIXG@213118|Desulfobacterales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ZZS2_k127_5726290_2	1340493.JNIF01000004_gene393	3.195e-116	388.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
ZZS2_k127_5726290_14	522306.CAP2UW1_2667	1.814e-09	62.0	28HTA@1|root,2Z806@2|Bacteria,1R7QM@1224|Proteobacteria,2W2CU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5726290_5	522306.CAP2UW1_2667	2.632e-99	337.0	28HTA@1|root,2Z806@2|Bacteria,1R7QM@1224|Proteobacteria,2W2CU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5748940_4	886293.Sinac_4630	3.409e-48	181.0	COG4692@1|root,COG4692@2|Bacteria,2IX4M@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
ZZS2_k127_5748940_1	497964.CfE428DRAFT_1994	7.845e-141	452.0	COG0329@1|root,COG0329@2|Bacteria,46TZB@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
ZZS2_k127_5748940_3	530564.Psta_2520	2.036e-68	241.0	COG2207@1|root,COG3829@1|root,COG2207@2|Bacteria,COG3829@2|Bacteria,2J1W9@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
ZZS2_k127_5748940_0	497964.CfE428DRAFT_1254	0.0	1273.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
ZZS2_k127_5748940_2	1278073.MYSTI_01256	3.517e-96	322.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,437Z5@68525|delta/epsilon subdivisions,2WZTS@28221|Deltaproteobacteria,2YUWA@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	-	-	-	ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001	-	-	-	RtcB
ZZS2_k127_5761303_8	153721.MYP_757	8.411e-10	72.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
ZZS2_k127_5761303_5	215803.DB30_6858	2.702e-19	104.0	COG3055@1|root,COG5563@1|root,COG3055@2|Bacteria,COG5563@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glyoxal oxidase N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1,Kelch_4
ZZS2_k127_5761303_0	314230.DSM3645_01791	5.214e-266	863.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWWI@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_5761303_4	867845.KI911784_gene2774	1.04e-51	204.0	COG1413@1|root,COG1674@1|root,COG5635@1|root,COG1413@2|Bacteria,COG1674@2|Bacteria,COG5635@2|Bacteria,2G8R0@200795|Chloroflexi,3766B@32061|Chloroflexia	32061|Chloroflexia	CDT	Armadillo/beta-catenin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_5761303_3	1121440.AUMA01000008_gene842	5.179e-87	304.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1R6YN@1224|Proteobacteria,42Q4G@68525|delta/epsilon subdivisions,2WJM9@28221|Deltaproteobacteria,2M947@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
ZZS2_k127_5761303_6	706587.Desti_0045	3.954e-16	91.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1NC2U@1224|Proteobacteria,4309P@68525|delta/epsilon subdivisions,2WVCV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
ZZS2_k127_5761303_2	1396141.BATP01000032_gene4314	1.435e-97	331.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_5761303_1	794903.OPIT5_00465	1.572e-146	478.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,3K7HJ@414999|Opitutae	414999|Opitutae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
ZZS2_k127_5761303_7	865937.Gilli_0729	8.88e-16	81.0	COG3011@1|root,COG3011@2|Bacteria,4NPGN@976|Bacteroidetes,1I2KY@117743|Flavobacteriia,2P7K2@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
ZZS2_k127_5770449_1	864051.BurJ1DRAFT_0895	6.29e-25	124.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
ZZS2_k127_5770449_0	583355.Caka_3109	1.779e-249	842.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
ZZS2_k127_5770449_2	497964.CfE428DRAFT_0808	5.406e-13	72.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb,RDD
ZZS2_k127_5785244_6	1396418.BATQ01000049_gene332	1.222e-102	347.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia,2IVBG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_5785244_15	639282.DEFDS_0733	6.7e-06	59.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.51,4.2.2.23	ko:K01206,ko:K18197	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29,PL11	-	AbfB,Bgal_small_N,CBM_6,F5_F8_type_C,Glyco_hydro_2_N,NPCBM
ZZS2_k127_5785244_3	1396141.BATP01000022_gene395	9.331e-114	381.0	COG1621@1|root,COG2382@1|root,COG1621@2|Bacteria,COG2382@2|Bacteria,46U0H@74201|Verrucomicrobia,2IVDH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_5785244_12	179408.Osc7112_3800	2.924e-26	115.0	COG0454@1|root,COG0456@2|Bacteria,1G7B4@1117|Cyanobacteria,1HHA6@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
ZZS2_k127_5785244_4	243233.MCA1875	1.847e-112	372.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bile acid sodium symporter	yocS	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
ZZS2_k127_5785244_2	1353529.M899_0311	3.382e-126	409.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
ZZS2_k127_5785244_1	452637.Oter_2839	8.339e-159	509.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_5785244_5	1267534.KB906754_gene3780	1.478e-106	349.0	COG0377@1|root,COG0377@2|Bacteria,3Y74G@57723|Acidobacteria,2JKT1@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
ZZS2_k127_5785244_9	1267534.KB906754_gene3779	3.038e-86	292.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
ZZS2_k127_5785244_14	713586.KB900536_gene401	1.348e-11	75.0	COG3009@1|root,COG3009@2|Bacteria,1N9IG@1224|Proteobacteria	1224|Proteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
ZZS2_k127_5785244_10	478741.JAFS01000001_gene1045	1.173e-54	203.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	iamC	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS2_k127_5785244_8	478741.JAFS01000001_gene1046	1.73e-90	308.0	COG1127@1|root,COG1127@2|Bacteria,46SRC@74201|Verrucomicrobia,37FUB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS2_k127_5785244_7	478741.JAFS01000001_gene1047	3.371e-98	333.0	COG0767@1|root,COG0767@2|Bacteria,46SY3@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS2_k127_5785244_0	234267.Acid_5331	4.001e-238	756.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_5785244_11	485918.Cpin_7074	1.118e-35	156.0	COG3115@1|root,COG3115@2|Bacteria,4PN8V@976|Bacteroidetes,1J0PP@117747|Sphingobacteriia	976|Bacteroidetes	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5788597_3	1122165.AUHS01000002_gene2905	9.004e-42	164.0	COG3021@1|root,COG3021@2|Bacteria	2|Bacteria	S	interspecies interaction between organisms	yafD	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_5788597_1	575540.Isop_0300	6.64e-128	422.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
ZZS2_k127_5788597_0	1403819.BATR01000093_gene2840	5.922e-215	679.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS2_k127_5788597_2	401053.AciPR4_1244	1.015e-52	195.0	COG3119@1|root,COG3119@2|Bacteria,3Y6D1@57723|Acidobacteria,2JK8D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS2_k127_5798459_2	1347368.HG964405_gene6101	1.909e-65	237.0	COG3391@1|root,COG4632@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	tagL	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Flg_new,NAGPA,SLH
ZZS2_k127_5798459_0	886293.Sinac_6957	0.0	1146.0	COG2010@1|root,COG2010@2|Bacteria,2J2GM@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_5798459_1	1396418.BATQ01000099_gene5533	2.105e-235	738.0	COG1524@1|root,COG1524@2|Bacteria,46TI1@74201|Verrucomicrobia,2IU16@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5798459_3	497964.CfE428DRAFT_5446	2.207e-13	78.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb,RDD
ZZS2_k127_5817594_11	63737.Npun_R2074	3.769e-18	92.0	2EFNF@1|root,339EK@2|Bacteria,1GFW8@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5817594_14	1254432.SCE1572_46925	9e-05	55.0	COG2372@1|root,COG2372@2|Bacteria,1Q28Q@1224|Proteobacteria,437VN@68525|delta/epsilon subdivisions,2WYPN@28221|Deltaproteobacteria,2YUBX@29|Myxococcales	28221|Deltaproteobacteria	S	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5817594_6	1210884.HG799462_gene7995	1.566e-53	203.0	29SH7@1|root,30DN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5817594_12	1121935.AQXX01000132_gene2657	7.208e-14	83.0	2AC29@1|root,311K9@2|Bacteria,1R66W@1224|Proteobacteria,1RYQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570,DUF4124
ZZS2_k127_5817594_10	278957.ABEA03000129_gene3558	7.088e-24	108.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,3K87P@414999|Opitutae	414999|Opitutae	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
ZZS2_k127_5817594_5	1345697.M493_05785	7.783e-81	279.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1WFGB@129337|Geobacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_5817594_8	1123257.AUFV01000018_gene3671	1.321e-26	121.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
ZZS2_k127_5817594_7	1049564.TevJSym_az00010	1.266e-26	130.0	COG2312@1|root,COG3386@1|root,COG3540@1|root,COG2312@2|Bacteria,COG3386@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Erythro_esteras,LTD
ZZS2_k127_5817594_1	583355.Caka_1736	5.97e-288	969.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_5817594_9	1349767.GJA_582	1.497e-25	126.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,477B2@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
ZZS2_k127_5817594_0	497964.CfE428DRAFT_2433	0.0	1199.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_5817594_2	1210884.HG799462_gene7951	6.785e-229	720.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5817594_3	886293.Sinac_3229	3.132e-185	604.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K02305,ko:K08738,ko:K09992	ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10,3.D.4.6	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_5817594_4	1210884.HG799469_gene14167	2.386e-148	483.0	COG3356@1|root,COG3356@2|Bacteria,2J1Z6@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_582035_14	1396141.BATP01000022_gene336	9.997e-09	66.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_582035_11	1396141.BATP01000022_gene335	2.385e-49	199.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_582035_0	382464.ABSI01000010_gene3258	2.072e-319	1063.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_582035_1	1120963.KB894499_gene422	6.533e-226	778.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_582035_10	926560.KE387023_gene2937	7.343e-81	277.0	COG2326@1|root,COG2326@2|Bacteria,1WKEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
ZZS2_k127_582035_15	103733.JNYO01000039_gene4413	1.977e-05	55.0	COG5520@1|root,COG5520@2|Bacteria,2I32Z@201174|Actinobacteria,4E177@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl hydrolase family 59	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_59,Glyco_hydro_59M,Laminin_G_3,RicinB_lectin_2,Ricin_B_lectin
ZZS2_k127_582035_6	1267535.KB906767_gene5494	1.59e-148	485.0	COG4948@1|root,COG4948@2|Bacteria,3Y6X2@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_582035_5	1396141.BATP01000020_gene19	3.002e-156	511.0	COG2271@1|root,COG2271@2|Bacteria,46U29@74201|Verrucomicrobia,2IV9J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_582035_8	243090.RB10165	4.881e-93	314.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
ZZS2_k127_582035_3	1123508.JH636439_gene876	4.329e-201	638.0	COG4102@1|root,COG4102@2|Bacteria,2IY49@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_582035_4	344747.PM8797T_15908	2.311e-196	649.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_582035_7	497964.CfE428DRAFT_1797	1.383e-143	468.0	COG0008@1|root,COG0008@2|Bacteria,46SJ3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ZZS2_k127_582035_13	497964.CfE428DRAFT_3472	1.042e-35	149.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia	74201|Verrucomicrobia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
ZZS2_k127_582035_2	926566.Terro_2389	9.652e-207	655.0	COG3119@1|root,COG3119@2|Bacteria,3Y7MP@57723|Acidobacteria,2JNZP@204432|Acidobacteriia	57723|Acidobacteria	P	TIGRFAM Tat (twin-arginine translocation) pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS2_k127_582035_12	1396141.BATP01000030_gene3705	5.311e-37	143.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_582035_9	1396141.BATP01000030_gene3706	4.105e-89	332.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS2_k127_5839853_4	266117.Rxyl_0760	1.444e-49	187.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS2_k127_5839853_5	1156937.MFUM_240013	1.089e-42	166.0	COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,37GRH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	DNA / pantothenate metabolism flavoprotein	-	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
ZZS2_k127_5839853_3	497964.CfE428DRAFT_6358	1.275e-55	204.0	COG0204@1|root,COG0204@2|Bacteria,46VUC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS2_k127_5839853_0	497964.CfE428DRAFT_6357	3.256e-87	294.0	COG3176@1|root,COG3176@2|Bacteria,46UGN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
ZZS2_k127_5839853_2	497964.CfE428DRAFT_0215	1.184e-60	222.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
ZZS2_k127_5839853_1	240016.ABIZ01000001_gene5630	1.027e-70	244.0	COG0386@1|root,COG0386@2|Bacteria,46V2M@74201|Verrucomicrobia,2IUDT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	GSHPx
ZZS2_k127_5839853_6	1185876.BN8_02868	1.089e-14	74.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5897603_29	686340.Metal_2108	1.128e-05	58.0	COG1073@1|root,COG1073@2|Bacteria,1R9V1@1224|Proteobacteria,1S4ZD@1236|Gammaproteobacteria,1XG0S@135618|Methylococcales	135618|Methylococcales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5897603_17	1201288.M900_1325	1.075e-78	278.0	29W47@1|root,30HP2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5897603_6	497964.CfE428DRAFT_0426	1.042e-119	400.0	2FD7A@1|root,3459A@2|Bacteria,46WSC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
ZZS2_k127_5897603_5	497964.CfE428DRAFT_2419	3.113e-124	420.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
ZZS2_k127_5897603_13	497964.CfE428DRAFT_2387	3.643e-91	323.0	COG0491@1|root,COG0491@2|Bacteria,46S7X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS2_k127_5897603_19	497964.CfE428DRAFT_4321	4.033e-67	231.0	COG4154@1|root,COG4154@2|Bacteria	2|Bacteria	G	fucose binding	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
ZZS2_k127_5897603_12	497964.CfE428DRAFT_4323	1.98e-91	308.0	COG1082@1|root,COG1082@2|Bacteria,46V2Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_5897603_15	1123508.JH636440_gene2700	1.323e-87	295.0	COG1878@1|root,COG1878@2|Bacteria,2J1IQ@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
ZZS2_k127_5897603_10	1499967.BAYZ01000040_gene2251	3.363e-103	344.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	fdh	-	1.1.1.316	ko:K17744	ko00053,ko01100,ko01110,map00053,map01100,map01110	M00114	R07675	RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
ZZS2_k127_5897603_23	497964.CfE428DRAFT_2063	1.341e-33	136.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
ZZS2_k127_5897603_16	497964.CfE428DRAFT_2062	1.569e-85	289.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
ZZS2_k127_5897603_4	497964.CfE428DRAFT_0899	4.759e-127	417.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
ZZS2_k127_5897603_9	1232410.KI421415_gene3062	2.721e-104	347.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,43U74@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_5897603_18	314230.DSM3645_02268	4.799e-68	246.0	COG0624@1|root,COG0624@2|Bacteria,2IYA5@203682|Planctomycetes	203682|Planctomycetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
ZZS2_k127_5897603_28	649831.L083_0796	6.717e-07	61.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Polysacc_synt,Polysacc_synt_3
ZZS2_k127_5897603_21	391623.TERMP_00885	8.552e-48	183.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_5897603_7	452637.Oter_0669	6.749e-116	378.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
ZZS2_k127_5897603_0	452637.Oter_0670	1.625e-321	993.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS2_k127_5897603_20	583355.Caka_1740	2.432e-51	192.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
ZZS2_k127_5897603_24	713587.THITH_09465	7.554e-31	130.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
ZZS2_k127_5897603_14	555079.Toce_0685	6.145e-88	312.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
ZZS2_k127_5897603_2	1144275.COCOR_02843	3.544e-180	582.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS2_k127_5897603_26	273068.TTE0606	9.955e-22	103.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,42GW8@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
ZZS2_k127_5897603_1	497964.CfE428DRAFT_3412	1.276e-188	600.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS2_k127_5897603_8	452637.Oter_3564	6.128e-106	358.0	COG2518@1|root,COG2518@2|Bacteria,46UEK@74201|Verrucomicrobia,3K7SY@414999|Opitutae	414999|Opitutae	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
ZZS2_k127_5897603_11	794903.OPIT5_30680	3.982e-97	333.0	COG5459@1|root,COG5459@2|Bacteria,46SNP@74201|Verrucomicrobia,3K8YT@414999|Opitutae	414999|Opitutae	J	Ribosomal small subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
ZZS2_k127_5897603_27	555088.DealDRAFT_0819	1.352e-09	73.0	COG2273@1|root,COG5337@1|root,COG2273@2|Bacteria,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia	186801|Clostridia	M	PFAM Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
ZZS2_k127_5897603_22	378806.STAUR_8259	2.766e-35	158.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CARDB,Peptidase_M30,VCBS
ZZS2_k127_5897603_3	497964.CfE428DRAFT_4940	2.619e-134	431.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
ZZS2_k127_5897603_25	497964.CfE428DRAFT_4941	2.665e-29	119.0	2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5910658_5	452637.Oter_2583	2.829e-84	288.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
ZZS2_k127_5910658_12	886293.Sinac_0803	4.261e-15	89.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
ZZS2_k127_5910658_13	1046714.AMRX01000006_gene2665	1.856e-14	84.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,465AM@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
ZZS2_k127_5910658_8	1191523.MROS_2048	1.262e-69	263.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
ZZS2_k127_5910658_2	452637.Oter_2584	4.265e-149	488.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
ZZS2_k127_5910658_1	1396141.BATP01000019_gene1673	5.296e-151	496.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
ZZS2_k127_5910658_3	448385.sce4705	2.71e-114	380.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
ZZS2_k127_5910658_9	1396141.BATP01000019_gene1675	1.217e-25	116.0	COG2010@1|root,COG2010@2|Bacteria,46VBT@74201|Verrucomicrobia,2IUG7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5910658_14	452637.Oter_3126	5.668e-12	75.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
ZZS2_k127_5910658_11	452637.Oter_2585	3.582e-15	79.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_5910658_10	1396141.BATP01000032_gene4392	2.564e-19	96.0	2DGAX@1|root,2ZV7P@2|Bacteria,46WTW@74201|Verrucomicrobia,2IW8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
ZZS2_k127_5910658_6	497964.CfE428DRAFT_0545	4.76e-81	279.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5910658_0	497964.CfE428DRAFT_0544	1.148e-182	603.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	497964.CfE428DRAFT_0544|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5910658_7	1449063.JMLS01000017_gene685	4.101e-74	259.0	COG1082@1|root,COG1082@2|Bacteria,1UFEU@1239|Firmicutes	1239|Firmicutes	G	Glycosyl-hydrolase 97 C-terminal, oligomerisation	-	-	-	-	-	-	-	-	-	-	-	-	GH97_C,GH97_N,Glyco_hydro_97
ZZS2_k127_5934374_4	331869.BAL199_21754	4.619e-101	334.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,4BSNZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
ZZS2_k127_5934374_2	452637.Oter_2581	1.199e-153	497.0	COG1252@1|root,COG1252@2|Bacteria,46SA2@74201|Verrucomicrobia,3K7SW@414999|Opitutae	414999|Opitutae	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ZZS2_k127_5934374_3	1396141.BATP01000059_gene2500	1.058e-135	447.0	COG2755@1|root,COG3664@1|root,COG2755@2|Bacteria,COG3664@2|Bacteria	2|Bacteria	G	PFAM glycoside hydrolase family 39	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Flg_new,Glyco_hydro_39,Lipase_GDSL_2
ZZS2_k127_5934374_6	941449.dsx2_2932	1.143e-06	59.0	COG0662@1|root,COG0662@2|Bacteria,1Q8SA@1224|Proteobacteria,432SV@68525|delta/epsilon subdivisions,2WY9Y@28221|Deltaproteobacteria,2MF5K@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_5934374_0	497964.CfE428DRAFT_0348	2.595e-240	771.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_5934374_5	497964.CfE428DRAFT_0347	7.611e-28	119.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5934374_1	497964.CfE428DRAFT_3154	1.058e-217	684.0	COG2833@1|root,COG2833@2|Bacteria,46TVR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5939366_4	1156937.MFUM_90002	1.57e-120	396.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia,37G3Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
ZZS2_k127_5939366_13	1002809.SSIL_3654	1.025e-19	102.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,26D50@186818|Planococcaceae	91061|Bacilli	U	COG1459 Type II secretory pathway, component PulF	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_5939366_11	497964.CfE428DRAFT_2471	1.097e-37	144.0	COG3118@1|root,COG3118@2|Bacteria,46VWK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ZZS2_k127_5939366_2	761193.Runsl_2422	3.176e-164	524.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5939366_9	373994.Riv7116_3284	2.951e-75	264.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	elrF	-	-	-	-	-	-	-	-	-	-	-	Cutinase,DUF1350,DUF1631
ZZS2_k127_5939366_15	1121921.KB898706_gene3122	1.157e-07	62.0	28N9P@1|root,2ZBDN@2|Bacteria,1R70P@1224|Proteobacteria,1RQ5R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
ZZS2_k127_5939366_10	886293.Sinac_2845	1.444e-65	243.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
ZZS2_k127_5939366_8	886293.Sinac_5380	1.66e-81	286.0	28PTH@1|root,2ZCER@2|Bacteria,2IZHG@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5939366_6	886293.Sinac_5379	2.924e-112	376.0	28K3C@1|root,2Z9SH@2|Bacteria,2IXIK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5939366_1	497964.CfE428DRAFT_1569	6.344e-196	629.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_5939366_14	1316936.K678_04036	8.812e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,2JR9I@204441|Rhodospirillales	204441|Rhodospirillales	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_5939366_3	497964.CfE428DRAFT_4760	2.57e-125	416.0	COG1082@1|root,COG1082@2|Bacteria,46SWE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_5939366_12	1396418.BATQ01000168_gene1823	8.439e-35	138.0	COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ZZS2_k127_5939366_0	1303518.CCALI_00609	4.12e-259	804.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
ZZS2_k127_5939366_5	880073.Calab_3191	4.209e-116	380.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
ZZS2_k127_5939366_7	1382359.JIAL01000001_gene680	1.631e-97	333.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
ZZS2_k127_5973021_12	1379698.RBG1_1C00001G0668	6.121e-06	57.0	COG2885@1|root,COG5276@1|root,COG2885@2|Bacteria,COG5276@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	DUF1566,Phenol_MetA_deg
ZZS2_k127_5973021_10	497964.CfE428DRAFT_4678	3.686e-11	74.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
ZZS2_k127_5973021_9	439235.Dalk_1207	7.367e-14	88.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2MIDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM RHS repeat-associated core	-	-	-	-	-	-	-	-	-	-	-	-	AHH,RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_5973021_0	1120963.KB894499_gene422	1.574e-151	542.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_5973021_5	1205680.CAKO01000028_gene4675	1.341e-56	228.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,2JQYU@204441|Rhodospirillales	204441|Rhodospirillales	Q	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
ZZS2_k127_5973021_2	1396141.BATP01000030_gene3631	2.736e-78	287.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	2|Bacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS2_k127_5973021_6	530564.Psta_2824	8.897e-55	204.0	COG0524@1|root,COG0524@2|Bacteria,2J3WH@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS2_k127_5973021_7	1123288.SOV_4c06580	1.371e-38	155.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H407@909932|Negativicutes	909932|Negativicutes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ZZS2_k127_5973021_3	497964.CfE428DRAFT_2429	8.409e-75	258.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3,DUF1080,PQQ,PQQ_2
ZZS2_k127_5973021_1	215803.DB30_7531	9.308e-117	413.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,43C2J@68525|delta/epsilon subdivisions,2X7D5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
ZZS2_k127_5973021_4	314230.DSM3645_05180	5.971e-61	232.0	COG2159@1|root,COG2159@2|Bacteria,2IYMW@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_5973021_11	491205.JARQ01000002_gene25	5.552e-08	65.0	COG5492@1|root,COG5492@2|Bacteria,4NH1K@976|Bacteroidetes,1HZUI@117743|Flavobacteriia,3ZP4P@59732|Chryseobacterium	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5986301_4	1068980.ARVW01000001_gene5232	1.795e-13	71.0	COG1506@1|root,COG1506@2|Bacteria,2H90U@201174|Actinobacteria,4DYSH@85010|Pseudonocardiales	201174|Actinobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
ZZS2_k127_5986301_1	1123278.KB893428_gene110	5.319e-126	408.0	COG0500@1|root,COG2226@2|Bacteria,4NFRD@976|Bacteroidetes,47MKY@768503|Cytophagia	976|Bacteroidetes	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS2_k127_5986301_5	377629.TERTU_0136	6.157e-07	64.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,1SE9G@1236|Gammaproteobacteria,2PPCF@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Ankyrin repeat	ank2	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
ZZS2_k127_5986301_3	1396141.BATP01000005_gene5990	1.727e-45	171.0	COG4185@1|root,COG4185@2|Bacteria,46XSJ@74201|Verrucomicrobia,2IWH1@203494|Verrucomicrobiae	2|Bacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
ZZS2_k127_5986301_0	509635.N824_15295	1.316e-130	445.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5986301_2	1173023.KE650771_gene3169	1.047e-73	252.0	COG0412@1|root,COG0412@2|Bacteria,1FZX6@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
ZZS2_k127_6035703_3	497964.CfE428DRAFT_2616	9.651e-07	52.0	28MB8@1|root,2ZAPS@2|Bacteria,46U9F@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6035703_0	497964.CfE428DRAFT_6713	9.855e-228	717.0	COG3961@1|root,COG3961@2|Bacteria,46UYW@74201|Verrucomicrobia	74201|Verrucomicrobia	GH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS2_k127_6035703_4	497964.CfE428DRAFT_4624	2.687e-05	54.0	COG0830@1|root,COG0830@2|Bacteria,46VJQ@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
ZZS2_k127_6035703_1	452637.Oter_0305	1.065e-155	496.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
ZZS2_k127_6035703_2	926569.ANT_05420	5.285e-72	253.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ZZS2_k127_6044673_1	525904.Tter_2008	2.377e-109	364.0	COG1063@1|root,COG1063@2|Bacteria,2NQTM@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	rspB	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	iYO844.BSU12330	ADH_N,ADH_zinc_N
ZZS2_k127_6044673_0	1267535.KB906767_gene4768	2.501e-138	454.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6044673_2	1297569.MESS2_760077	2.467e-109	359.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lactamase_B_2,Lactamase_B_3
ZZS2_k127_6044673_3	1297570.MESS4_340145	1.716e-70	245.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,43HSN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS2_k127_6061157_3	555779.Dthio_PD2120	9.106e-128	417.0	28YQ6@1|root,2ZKHR@2|Bacteria,1RBSV@1224|Proteobacteria,42YMY@68525|delta/epsilon subdivisions,2WTVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6061157_9	439235.Dalk_0737	3.473e-35	138.0	COG1396@1|root,COG1396@2|Bacteria,1N678@1224|Proteobacteria,430MN@68525|delta/epsilon subdivisions,2WW40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
ZZS2_k127_6061157_10	224911.27350827	1.186e-07	53.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6061157_0	452637.Oter_2706	7.499e-188	597.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,3K7NC@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
ZZS2_k127_6061157_2	1123508.JH636449_gene7418	1.967e-139	462.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_6061157_4	344747.PM8797T_09479	1.185e-110	378.0	COG2382@1|root,COG2382@2|Bacteria,2J2KX@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_6061157_5	497964.CfE428DRAFT_3322	4.88e-107	358.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
ZZS2_k127_6061157_7	525904.Tter_0170	3.205e-69	251.0	COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
ZZS2_k127_6061157_11	36874.HQ34_07705	4.218e-06	61.0	COG0457@1|root,COG0457@2|Bacteria	36874.HQ34_07705|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6061157_6	314230.DSM3645_20862	3.552e-94	322.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6061157_8	439235.Dalk_0708	3.324e-39	159.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
ZZS2_k127_6061157_1	794903.OPIT5_19015	3.179e-159	520.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
ZZS2_k127_6068423_6	1341181.FLJC2902T_15110	7.031e-90	334.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
ZZS2_k127_6068423_15	391613.RTM1035_09848	5.084e-28	133.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46RE2@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_M10_C
ZZS2_k127_6068423_12	388467.A19Y_1747	1.183e-36	162.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Peptidase_S8,SdrD_B
ZZS2_k127_6068423_2	530564.Psta_2637	5.215e-185	620.0	COG2133@1|root,COG2133@2|Bacteria,2IY0M@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_6068423_13	662479.C440_03508	8.305e-31	128.0	arCOG07754@1|root,arCOG07754@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6068423_7	530564.Psta_1917	3.454e-77	267.0	COG4099@1|root,COG4099@2|Bacteria,2IZFN@203682|Planctomycetes	203682|Planctomycetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_6068423_0	382464.ABSI01000012_gene2136	2.799e-291	910.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
ZZS2_k127_6068423_9	700598.Niako_5650	4.645e-61	218.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
ZZS2_k127_6068423_18	1499967.BAYZ01000119_gene3208	6.696e-20	102.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS2_k127_6068423_19	314256.OG2516_14456	6.015e-06	61.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG3637@1|root,COG5276@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2UHRC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FGMQ	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,He_PIG,Laminin_G_3
ZZS2_k127_6068423_17	1280685.AUKC01000003_gene2921	3.703e-22	108.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_2
ZZS2_k127_6068423_16	596151.DesfrDRAFT_2582	4.034e-23	112.0	COG0438@1|root,COG0438@2|Bacteria,1MWEM@1224|Proteobacteria,42U3H@68525|delta/epsilon subdivisions,2WQBB@28221|Deltaproteobacteria,2M8EK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6068423_21	211165.AJLN01000116_gene2989	0.0008616	51.0	COG1413@1|root,COG1413@2|Bacteria,1G511@1117|Cyanobacteria,1JJSP@1189|Stigonemataceae	1117|Cyanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_6068423_20	1123508.JH636444_gene5142	0.0006192	51.0	COG1413@1|root,COG1413@2|Bacteria,2J3BS@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_6068423_4	867845.KI911784_gene2902	1.661e-118	389.0	COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi,37752@32061|Chloroflexia	32061|Chloroflexia	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ZZS2_k127_6068423_3	572265.HDEF_0187	5.494e-128	423.0	COG0241@1|root,COG0572@1|root,COG1208@1|root,COG0241@2|Bacteria,COG0572@2|Bacteria,COG1208@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,283FX@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033692,GO:0034200,GO:0034637,GO:0034645,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046872,GO:0046914,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iB21_1397.B21_00198,iEC55989_1330.EC55989_0198,iECBD_1354.ECBD_3418,iECB_1328.ECB_00199,iECD_1391.ECD_00199,iECIAI1_1343.ECIAI1_0202,iECO103_1326.ECO103_0200,iECSE_1348.ECSE_0202,iETEC_1333.ETEC_0196,iEcHS_1320.EcHS_A0204,iEcolC_1368.EcolC_3459	HAD_2,Hydrolase_like
ZZS2_k127_6068423_5	572265.HDEF_0189	2.794e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,1S2XS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Nad-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS2_k127_6068423_10	452637.Oter_3648	1.814e-38	158.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
ZZS2_k127_6068423_1	1123276.KB893290_gene5224	1.448e-211	667.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS2_k127_6068423_8	452637.Oter_2583	3.926e-76	264.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
ZZS2_k127_6068423_14	497964.CfE428DRAFT_3521	5.973e-30	139.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	2|Bacteria	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_6087301_1	330214.NIDE2028	2.777e-76	272.0	COG2831@1|root,COG2831@2|Bacteria	2|Bacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,POTRA_2,ShlB
ZZS2_k127_6087301_0	395493.BegalDRAFT_0706	7.135e-78	292.0	COG3210@1|root,COG3210@2|Bacteria,1QMZZ@1224|Proteobacteria,1SG2Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
ZZS2_k127_6087301_2	880071.Fleli_0996	4.469e-19	101.0	COG1319@1|root,COG2911@1|root,COG3420@1|root,COG4257@1|root,COG1319@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	4.2.2.3	ko:K01729,ko:K12287,ko:K13277,ko:K20276	ko00051,ko02024,map00051,map02024	-	R03706	-	ko00000,ko00001,ko01000,ko01002,ko02044,ko03110	-	-	-	Beta_helix,FAD_binding_5
ZZS2_k127_6098975_14	1303518.CCALI_00782	2.004e-80	285.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
ZZS2_k127_6098975_16	1303518.CCALI_00781	5.07e-72	254.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE_1	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ZZS2_k127_6098975_37	1403819.BATR01000181_gene6183	1.631e-25	117.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS2_k127_6098975_10	1122604.JONR01000009_gene2394	1.776e-113	372.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,1RN80@1236|Gammaproteobacteria,1X3KN@135614|Xanthomonadales	135614|Xanthomonadales	O	aspartyl asparaginyl beta-hydroxylase	aspH	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
ZZS2_k127_6098975_48	1396141.BATP01000057_gene3049	2.823e-08	70.0	COG1404@1|root,COG2931@1|root,COG5267@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG5267@2|Bacteria,46XBA@74201|Verrucomicrobia,2IV9X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	H-type lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_6098975_31	926550.CLDAP_29960	5.847e-32	149.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD
ZZS2_k127_6098975_0	1396141.BATP01000034_gene4198	0.0	1387.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_6098975_35	1396141.BATP01000030_gene3719	3.764e-28	136.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
ZZS2_k127_6098975_24	153721.MYP_2462	7.302e-39	171.0	COG2730@1|root,COG3325@1|root,COG3469@1|root,COG5295@1|root,COG2730@2|Bacteria,COG3325@2|Bacteria,COG3469@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
ZZS2_k127_6098975_41	251221.35213566	1.943e-22	117.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6098975_13	497964.CfE428DRAFT_3399	2.012e-81	290.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_6098975_2	886293.Sinac_4412	2.129e-216	701.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,2J0NC@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6098975_38	278957.ABEA03000147_gene4459	2.061e-24	113.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_6098975_45	1454007.JAUG01000107_gene1044	5.126e-14	85.0	COG2730@1|root,COG4166@1|root,COG5295@1|root,COG2730@2|Bacteria,COG4166@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1IPUC@117747|Sphingobacteriia	976|Bacteroidetes	EUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
ZZS2_k127_6098975_44	644283.Micau_1136	3.878e-14	86.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6098975_7	489825.LYNGBM3L_21200	6.779e-135	450.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_6098975_9	251229.Chro_2350	2.141e-134	453.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,3VINJ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
ZZS2_k127_6098975_25	1123248.KB893322_gene635	1.003e-37	149.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
ZZS2_k127_6098975_29	1123248.KB893322_gene634	6.762e-35	142.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
ZZS2_k127_6098975_4	335543.Sfum_3551	1.639e-159	515.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria,42Y8X@68525|delta/epsilon subdivisions,2WU97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6098975_8	489825.LYNGBM3L_21170	1.173e-134	441.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS2_k127_6098975_17	251229.Chro_0879	6.057e-65	234.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,3VKAC@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6098975_26	335541.Swol_2445	1.567e-37	149.0	COG2120@1|root,COG2120@2|Bacteria,1TUFP@1239|Firmicutes,25PKR@186801|Clostridia,42KY4@68298|Syntrophomonadaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS2_k127_6098975_15	56110.Oscil6304_2662	9.502e-74	266.0	COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria,1HEY0@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase 4-like domain	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6098975_49	886293.Sinac_1912	2.717e-05	56.0	COG0500@1|root,COG2226@2|Bacteria,2J292@203682|Planctomycetes	203682|Planctomycetes	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_6098975_34	489825.LYNGBM3L_21130	2.423e-28	128.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6098975_27	1121091.AUMP01000011_gene1779	5.603e-37	151.0	COG0438@1|root,COG0438@2|Bacteria,1V4TS@1239|Firmicutes,4HC19@91061|Bacilli	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
ZZS2_k127_6098975_43	251229.Chro_2352	5.348e-20	101.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
ZZS2_k127_6098975_11	1120950.KB892751_gene6726	6.074e-113	377.0	COG0673@1|root,COG0673@2|Bacteria,2GMB0@201174|Actinobacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_6098975_30	35754.JNYJ01000117_gene1586	5.888e-33	145.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria,4D8K4@85008|Micromonosporales	201174|Actinobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,RicinB_lectin_2,Ricin_B_lectin,ThuA
ZZS2_k127_6098975_20	504472.Slin_5719	1.757e-53	207.0	2DBQG@1|root,2ZADX@2|Bacteria,4NNCV@976|Bacteroidetes,47XAF@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_6098975_5	1173021.ALWA01000006_gene3130	4.502e-148	476.0	COG0722@1|root,COG0722@2|Bacteria,1G35W@1117|Cyanobacteria	1117|Cyanobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ZZS2_k127_6098975_36	398767.Glov_2353	2.953e-27	123.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,43W1K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS2_k127_6098975_21	497964.CfE428DRAFT_2959	1.465e-51	194.0	2ED0A@1|root,336X9@2|Bacteria,46TCE@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6098975_32	554065.XP_005846247.1	1.536e-31	132.0	COG1011@1|root,KOG3085@2759|Eukaryota,382V1@33090|Viridiplantae	33090|Viridiplantae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6098975_18	1463856.JOHY01000002_gene1179	4.277e-64	225.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
ZZS2_k127_6098975_40	1121472.AQWN01000007_gene1087	3.424e-24	105.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,262CP@186807|Peptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
ZZS2_k127_6098975_6	240016.ABIZ01000001_gene2323	1.208e-136	460.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,2ITGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
ZZS2_k127_6098975_3	344747.PM8797T_17402	2.642e-168	540.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_6098975_47	1304275.C41B8_14425	9.902e-12	69.0	2E7KC@1|root,3322E@2|Bacteria,1NBFM@1224|Proteobacteria,1SDU2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6098975_28	382464.ABSI01000001_gene4245	2.053e-36	144.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
ZZS2_k127_6098975_1	1173024.KI912148_gene4571	0.0	1048.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1JMTM@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
ZZS2_k127_6098975_23	927658.AJUM01000034_gene376	3.578e-45	192.0	COG2133@1|root,COG2312@1|root,COG5563@1|root,COG2133@2|Bacteria,COG2312@2|Bacteria,COG5563@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
ZZS2_k127_6098975_46	1396141.BATP01000042_gene1928	2.33e-13	86.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_6098975_12	1396141.BATP01000043_gene1929	7.276e-96	359.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_6098975_50	1155714.KB891997_gene497	0.000152	57.0	COG0671@1|root,COG1409@1|root,COG3537@1|root,COG0671@2|Bacteria,COG1409@2|Bacteria,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92,PAP2,Ricin_B_lectin
ZZS2_k127_6098975_22	313603.FB2170_10111	1.571e-45	193.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_6098975_19	926562.Oweho_0246	3.08e-59	235.0	COG3211@1|root,COG3211@2|Bacteria,4NZ53@976|Bacteroidetes,1IN2H@117743|Flavobacteriia,2PC64@246874|Cryomorphaceae	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_6098975_39	1396141.BATP01000059_gene2520	2.275e-24	121.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
ZZS2_k127_6098975_42	583355.Caka_1736	9.864e-22	112.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_612811_10	575540.Isop_0616	1.281e-33	139.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
ZZS2_k127_612811_6	103733.JNYO01000021_gene6767	7.017e-49	194.0	COG3866@1|root,COG3866@2|Bacteria,2GNKW@201174|Actinobacteria,4E1TN@85010|Pseudonocardiales	201174|Actinobacteria	G	Amb_all	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	DUF1080,Pec_lyase_C
ZZS2_k127_612811_12	794903.OPIT5_29020	6.631e-06	58.0	2A1XY@1|root,32Q1C@2|Bacteria,46X79@74201|Verrucomicrobia,3K95A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_612811_7	1304885.AUEY01000028_gene2795	4.159e-46	172.0	COG4339@1|root,COG4339@2|Bacteria,1QV5J@1224|Proteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_612811_3	234267.Acid_6615	3.645e-67	241.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_612811_0	314230.DSM3645_16425	6.608e-209	662.0	COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes	203682|Planctomycetes	C	COG1012 NAD-dependent aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
ZZS2_k127_612811_9	313612.L8106_12700	9.216e-35	154.0	COG2931@1|root,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria,1H9Z9@1150|Oscillatoriales	1117|Cyanobacteria	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,SdrD_B,VCBS
ZZS2_k127_612811_1	1123242.JH636434_gene5158	1.095e-166	531.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
ZZS2_k127_612811_2	1210884.HG799474_gene15102	1.503e-95	333.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_612811_5	1304885.AUEY01000018_gene1100	4.849e-54	202.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
ZZS2_k127_612811_4	1121468.AUBR01000005_gene53	2.659e-66	240.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,42EX3@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
ZZS2_k127_612811_8	195250.CM001776_gene3255	1.256e-40	158.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,TPMT
ZZS2_k127_6135730_0	925409.KI911562_gene299	1.274e-152	501.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
ZZS2_k127_6148206_6	452637.Oter_1456	8.759e-84	295.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_6148206_12	243231.GSU0396	5.346e-20	95.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42XFU@68525|delta/epsilon subdivisions,2WSTK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
ZZS2_k127_6148206_15	357809.Cphy_0652	2.082e-10	62.0	2AD44@1|root,312SG@2|Bacteria,1VMSV@1239|Firmicutes,24W2P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6148206_11	1185876.BN8_02686	5.288e-23	113.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1,Rhodanese
ZZS2_k127_6148206_5	314278.NB231_08740	2.415e-99	340.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1WX09@135613|Chromatiales	135613|Chromatiales	P	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
ZZS2_k127_6148206_7	1267535.KB906767_gene3226	2.918e-44	169.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6148206_14	926550.CLDAP_20590	5.991e-11	66.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
ZZS2_k127_6148206_3	1121405.dsmv_0184	1.891e-163	527.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2MIF6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
ZZS2_k127_6148206_10	589873.EP13_18250	3.38e-33	132.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria,4682B@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
ZZS2_k127_6148206_4	497964.CfE428DRAFT_1191	1.518e-135	441.0	COG3288@1|root,COG3288@2|Bacteria,46SFW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
ZZS2_k127_6148206_1	402777.KB235904_gene3597	0.0	1138.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1H81U@1150|Oscillatoriales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
ZZS2_k127_6148206_0	478741.JAFS01000002_gene551	0.0	1211.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46SVA@74201|Verrucomicrobia,37FY0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS2_k127_6148206_9	330214.NIDE1927	3.212e-38	156.0	COG0589@1|root,COG0589@2|Bacteria,3J1A7@40117|Nitrospirae	40117|Nitrospirae	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS2_k127_6148206_8	247490.KSU1_A0074	1.731e-39	152.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS2_k127_6148206_13	1123242.JH636435_gene3081	7.895e-18	90.0	2E9ZY@1|root,3345D@2|Bacteria,2J1FP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6148206_2	521674.Plim_0263	7.03e-321	1007.0	COG0474@1|root,COG0474@2|Bacteria,2IXV7@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,SBP_bac_1
ZZS2_k127_6164917_3	452637.Oter_1808	1.17e-80	281.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
ZZS2_k127_6164917_2	344747.PM8797T_00347	4.17e-125	412.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
ZZS2_k127_6164917_0	1303518.CCALI_00277	1.761e-244	782.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PD40,PSCyt1,PSCyt2,PSD1,WD40
ZZS2_k127_6164917_6	1123256.KB907927_gene1556	2.085e-17	83.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6164917_1	1303518.CCALI_00278	6.873e-215	677.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_6164917_4	344747.PM8797T_11209	2.867e-41	175.0	COG2319@1|root,COG2319@2|Bacteria,2J53E@203682|Planctomycetes	203682|Planctomycetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6164917_5	1123242.JH636436_gene182	2.989e-22	101.0	COG2319@1|root,COG2319@2|Bacteria,2IWR9@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PSCyt1,WD40
ZZS2_k127_6166960_4	1396418.BATQ01000088_gene1040	1.277e-114	377.0	COG0329@1|root,COG0329@2|Bacteria,46UU4@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS2_k127_6166960_2	497964.CfE428DRAFT_4155	2.724e-261	817.0	COG1069@1|root,COG1069@2|Bacteria,46UI3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
ZZS2_k127_6166960_1	240016.ABIZ01000001_gene3305	2.213e-264	828.0	COG2407@1|root,COG2407@2|Bacteria,46SGK@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
ZZS2_k127_6166960_3	886293.Sinac_5718	5.499e-182	585.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
ZZS2_k127_6166960_0	497964.CfE428DRAFT_0990	7.298e-274	859.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
ZZS2_k127_6166960_5	452637.Oter_0795	5.858e-22	102.0	2E5WH@1|root,32RS6@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS2_k127_6168100_4	1396141.BATP01000003_gene4934	1.188e-115	415.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_6168100_8	452637.Oter_2184	4.986e-21	110.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
ZZS2_k127_6168100_10	1403819.BATR01000011_gene422	6.353e-07	64.0	COG4932@1|root,COG5267@1|root,COG5492@1|root,COG4932@2|Bacteria,COG5267@2|Bacteria,COG5492@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_6168100_0	497964.CfE428DRAFT_0809	4.166e-188	599.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6168100_2	497964.CfE428DRAFT_5675	7.727e-124	407.0	COG0583@1|root,COG0583@2|Bacteria,46TQR@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_6168100_6	1403819.BATR01000169_gene5809	1.12e-44	167.0	2EA0N@1|root,33462@2|Bacteria,46WE5@74201|Verrucomicrobia,2IWBB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6168100_11	1163409.UUA_10711	1.477e-05	57.0	2ERQB@1|root,30AXX@2|Bacteria,1QTA1@1224|Proteobacteria,1T7ZB@1236|Gammaproteobacteria,1X9YN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6168100_12	87626.PTD2_04958	0.0006157	42.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6168100_1	595460.RRSWK_05376	1.21e-146	488.0	COG1409@1|root,COG1409@2|Bacteria,2J2E9@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
ZZS2_k127_6168100_5	1198452.Jab_1c23560	2.929e-65	231.0	COG4430@1|root,COG4430@2|Bacteria,1RG2R@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
ZZS2_k127_6168100_9	1396141.BATP01000003_gene5142	8.782e-08	65.0	COG4625@1|root,COG5492@1|root,COG4625@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PATR,Peptidase_S8
ZZS2_k127_6168100_7	1123288.SOV_3c03590	2.157e-26	122.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,4H2PV@909932|Negativicutes	909932|Negativicutes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS2_k127_6168100_3	583355.Caka_2169	1.087e-116	395.0	COG2203@1|root,COG3605@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,3K7H5@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
ZZS2_k127_6185103_4	1396141.BATP01000039_gene1272	6.728e-18	96.0	COG2374@1|root,COG3204@1|root,COG3540@1|root,COG4222@1|root,COG2374@2|Bacteria,COG3204@2|Bacteria,COG3540@2|Bacteria,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD,Phytase-like,SdiA-regulated,VPEP
ZZS2_k127_6185103_3	497964.CfE428DRAFT_4864	5.587e-62	222.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6185103_1	886293.Sinac_6489	6.187e-80	293.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_6185103_7	1304275.C41B8_06502	3.017e-06	59.0	2C99D@1|root,2Z7Y8@2|Bacteria,1R5JY@1224|Proteobacteria,1SI3Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
ZZS2_k127_6185103_2	1242864.D187_009616	4.721e-67	246.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
ZZS2_k127_6185103_5	755732.Fluta_1212	8.265e-14	87.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_6185103_0	583355.Caka_1736	6.395e-253	856.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_6185103_6	278957.ABEA03000021_gene1719	3.26e-13	85.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6189221_4	886293.Sinac_2603	1.419e-56	202.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS2_k127_6189221_1	240016.ABIZ01000001_gene3058	1.885e-132	432.0	COG0473@1|root,COG0473@2|Bacteria,46S4R@74201|Verrucomicrobia,2ITY1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS2_k127_6189221_0	497964.CfE428DRAFT_0210	1.994e-139	456.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia	74201|Verrucomicrobia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_6189221_6	497964.CfE428DRAFT_1105	1.802e-42	170.0	COG1427@1|root,COG1427@2|Bacteria,46VTU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS2_k127_6189221_2	204536.SULAZ_0984	1.487e-107	361.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
ZZS2_k127_6189221_3	880073.Calab_0464	2.731e-60	219.0	COG0382@1|root,COG0382@2|Bacteria,2NP4W@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
ZZS2_k127_6189221_5	886293.Sinac_2104	8.463e-52	188.0	COG1680@1|root,COG1680@2|Bacteria,2IWSV@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_6218482_4	861299.J421_6009	1.509e-16	80.0	2E328@1|root,32Y2G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6218482_3	439235.Dalk_3988	8.628e-21	98.0	COG3809@1|root,COG3809@2|Bacteria,1QSA6@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
ZZS2_k127_6218482_6	886293.Sinac_1023	6.004e-09	69.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
ZZS2_k127_6218482_2	251221.35213566	2.643e-28	132.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6218482_0	1396141.BATP01000060_gene4727	2.744e-229	752.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_6218482_5	1396141.BATP01000051_gene3310	1.611e-11	74.0	COG3209@1|root,COG3266@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,MucBP,Phospholip_A2_3,YSIRK_signal
ZZS2_k127_6218482_1	1396141.BATP01000022_gene335	1.983e-45	186.0	29RTN@1|root,30CXJ@2|Bacteria,46XB6@74201|Verrucomicrobia,2IV96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6241993_15	478741.JAFS01000002_gene875	2.284e-32	134.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
ZZS2_k127_6241993_11	1396418.BATQ01000137_gene3859	1.443e-60	218.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,2IU8P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	COX2
ZZS2_k127_6241993_18	502025.Hoch_2422	0.0006907	48.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WTH0@28221|Deltaproteobacteria,2YVPQ@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
ZZS2_k127_6241993_6	481448.Minf_1950	3.504e-90	304.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
ZZS2_k127_6241993_0	497964.CfE428DRAFT_2230	1.252e-253	797.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
ZZS2_k127_6241993_7	1267535.KB906767_gene1277	4.689e-80	276.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
ZZS2_k127_6241993_8	481448.Minf_1426	9.906e-72	256.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
ZZS2_k127_6241993_13	639030.JHVA01000001_gene2022	1.13e-38	154.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_6241993_9	497964.CfE428DRAFT_2863	2.417e-68	244.0	COG3515@1|root,COG3515@2|Bacteria,46WW4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImpA, N-terminal, type VI secretion system	-	-	-	-	-	-	-	-	-	-	-	-	ImpA_N
ZZS2_k127_6241993_17	439235.Dalk_2629	1.127e-18	101.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria,2MKB1@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
ZZS2_k127_6241993_14	497964.CfE428DRAFT_2859	2.557e-36	158.0	28SQ5@1|root,2ZF09@2|Bacteria,46WN6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6241993_5	1396141.BATP01000024_gene782	2.913e-102	372.0	COG3523@1|root,COG3523@2|Bacteria,46VI0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ImcF-related N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ImcF-related_N
ZZS2_k127_6241993_12	497964.CfE428DRAFT_2854	1.093e-56	207.0	2DXSN@1|root,346BX@2|Bacteria,46W22@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Type VI secretion system protein DotU	-	-	-	-	-	-	-	-	-	-	-	-	DotU
ZZS2_k127_6241993_2	497964.CfE428DRAFT_2853	1.677e-178	570.0	COG3522@1|root,COG3522@2|Bacteria,46UPG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VasE
ZZS2_k127_6241993_10	497964.CfE428DRAFT_2852	3.008e-61	223.0	2BZ98@1|root,2ZRHF@2|Bacteria,46WMB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6241993_4	497964.CfE428DRAFT_2271	1.023e-105	362.0	COG1477@1|root,COG1477@2|Bacteria,46V70@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ZZS2_k127_6241993_16	497964.CfE428DRAFT_4189	3.555e-30	124.0	COG0782@1|root,COG0782@2|Bacteria,46W8B@74201|Verrucomicrobia	74201|Verrucomicrobia	J	PFAM transcription elongation factor GreA GreB domain protein	-	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB
ZZS2_k127_6241993_1	1396141.BATP01000030_gene3702	6.03e-245	777.0	COG3934@1|root,COG5520@1|root,COG3934@2|Bacteria,COG5520@2|Bacteria,46Z5X@74201|Verrucomicrobia,2IWQJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6241993_3	1123242.JH636438_gene5875	6.475e-165	529.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_6268228_0	861299.J421_5672	2.155e-242	764.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Glyco_hydro_63
ZZS2_k127_6268228_1	1496688.ER33_11555	6.126e-238	753.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
ZZS2_k127_6268228_2	716544.wcw_0442	5.118e-124	404.0	COG1028@1|root,COG1028@2|Bacteria,2JG7F@204428|Chlamydiae	204428|Chlamydiae	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
ZZS2_k127_6268228_3	497964.CfE428DRAFT_5990	4.936e-62	220.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6268228_4	1123242.JH636434_gene4617	1.593e-47	184.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
ZZS2_k127_6268228_5	362418.IW19_20215	9.49e-40	161.0	COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,1I3FC@117743|Flavobacteriia,2NWJX@237|Flavobacterium	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
ZZS2_k127_6292999_6	584708.Apau_2309	4.421e-25	122.0	COG3210@1|root,COG3210@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_6292999_1	1396141.BATP01000025_gene980	3.498e-83	283.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_6292999_5	1396141.BATP01000025_gene979	3.175e-30	126.0	COG1017@1|root,COG1017@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Globin
ZZS2_k127_6292999_3	1396141.BATP01000036_gene3849	1.855e-64	231.0	29ZND@1|root,30MNX@2|Bacteria,46XFT@74201|Verrucomicrobia,2IVSW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6292999_0	497964.CfE428DRAFT_1981	2.962e-90	315.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
ZZS2_k127_6292999_8	1463917.JODC01000008_gene3515	5.312e-06	50.0	COG4034@1|root,COG4034@2|Bacteria,2GNTY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1152
ZZS2_k127_6292999_2	240016.ABIZ01000001_gene4035	1.095e-65	227.0	COG5113@1|root,COG3236@2|Bacteria,46XQP@74201|Verrucomicrobia,2IWDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain of unknown function (DUF1768)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768
ZZS2_k127_6292999_4	1227453.C444_15433	8.34e-34	138.0	COG0500@1|root,arCOG01791@2157|Archaea,2XW4Y@28890|Euryarchaeota,23VJQ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_6313072_2	1396141.BATP01000025_gene992	1.316e-99	349.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia,2IU71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
ZZS2_k127_6313072_1	497964.CfE428DRAFT_3531	2.922e-112	372.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
ZZS2_k127_6313072_4	497964.CfE428DRAFT_1579	5.323e-38	145.0	COG0853@1|root,COG0853@2|Bacteria,46W3T@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
ZZS2_k127_6313072_0	497964.CfE428DRAFT_5922	2.131e-208	653.0	COG0673@1|root,COG0673@2|Bacteria,46TXS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_6313072_5	290315.Clim_0581	3.252e-26	113.0	2EPQK@1|root,33HB5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6313072_3	857087.Metme_3377	2.118e-59	222.0	COG1686@1|root,COG1686@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4,6.3.2.10	ko:K01929,ko:K07258	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
ZZS2_k127_6335899_6	1403819.BATR01000114_gene3902	8.862e-92	304.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6335899_8	497964.CfE428DRAFT_4728	1.458e-48	182.0	COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6335899_10	497964.CfE428DRAFT_4835	2.276e-42	159.0	COG4747@1|root,COG4747@2|Bacteria,46WIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
ZZS2_k127_6335899_12	234267.Acid_5324	1.06e-33	136.0	COG2271@1|root,COG2271@2|Bacteria,3Y47N@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
ZZS2_k127_6335899_15	1131553.JIBI01000050_gene997	1.723e-14	79.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2VVYY@28216|Betaproteobacteria,374GW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
ZZS2_k127_6335899_14	1382306.JNIM01000001_gene1681	2.489e-18	86.0	28SF2@1|root,2ZERN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6335899_7	1142394.PSMK_04410	1.853e-87	302.0	COG2982@1|root,COG2982@2|Bacteria,2J4AC@203682|Planctomycetes	203682|Planctomycetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
ZZS2_k127_6335899_11	1142394.PSMK_04420	2.846e-34	142.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
ZZS2_k127_6335899_9	1042377.AFPJ01000028_gene2147	1.06e-45	169.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria,46B5Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
ZZS2_k127_6335899_4	1267534.KB906756_gene354	9.699e-125	413.0	COG2768@1|root,COG2768@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088,DUF362
ZZS2_k127_6335899_3	530564.Psta_1696	3.717e-126	427.0	COG3064@1|root,COG3064@2|Bacteria,2IXYB@203682|Planctomycetes	203682|Planctomycetes	M	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
ZZS2_k127_6335899_0	1173027.Mic7113_1425	0.0	2355.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H9JF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
ZZS2_k127_6335899_1	1173028.ANKO01000041_gene3223	3.933e-284	876.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
ZZS2_k127_6335899_13	1122223.KB890688_gene1781	2.24e-25	111.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
ZZS2_k127_6335899_2	794903.OPIT5_08095	1.388e-131	428.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,3K7TX@414999|Opitutae	414999|Opitutae	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
ZZS2_k127_6335899_5	1210884.HG799464_gene10465	1.738e-121	406.0	COG0613@1|root,COG0613@2|Bacteria,2IX3G@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6345465_12	1121904.ARBP01000017_gene5073	1.721e-49	201.0	COG1858@1|root,COG2273@1|root,COG3391@1|root,COG3401@1|root,COG4733@1|root,COG5276@1|root,COG5492@1|root,COG1858@2|Bacteria,COG2273@2|Bacteria,COG3391@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,COG5276@2|Bacteria,COG5492@2|Bacteria,4NIPP@976|Bacteroidetes,47JEG@768503|Cytophagia	976|Bacteroidetes	C	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_3,Cytochrom_C,Cytochrom_D1,PKD
ZZS2_k127_6345465_2	1267535.KB906767_gene230	1.59e-183	595.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
ZZS2_k127_6345465_17	1123242.JH636435_gene1361	9.94e-12	76.0	2ESSA@1|root,33KAQ@2|Bacteria,2J1KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6345465_16	886293.Sinac_2505	7.097e-13	79.0	2ESSA@1|root,33KAQ@2|Bacteria,2J1KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6345465_6	1379698.RBG1_1C00001G0194	4.941e-97	357.0	COG3211@1|root,COG3540@1|root,COG3211@2|Bacteria,COG3540@2|Bacteria,2NS16@2323|unclassified Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoX	-	3.1.3.1	ko:K01113,ko:K07093	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF839
ZZS2_k127_6345465_0	1183438.GKIL_3722	2.194e-231	762.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
ZZS2_k127_6345465_3	497964.CfE428DRAFT_4581	2.971e-166	551.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
ZZS2_k127_6345465_10	1210884.HG799468_gene13746	1.611e-82	295.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_6345465_13	335543.Sfum_1007	3.632e-43	176.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_6345465_15	382464.ABSI01000013_gene1700	3.92e-33	136.0	COG3437@1|root,COG3437@2|Bacteria,46UU1@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
ZZS2_k127_6345465_5	765952.PUV_11340	1.345e-122	408.0	COG2204@1|root,COG2204@2|Bacteria,2JFQI@204428|Chlamydiae	204428|Chlamydiae	T	Sigma-54 dependent response regulator	atoC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_6345465_4	344747.PM8797T_26465	1.129e-133	438.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
ZZS2_k127_6345465_14	335543.Sfum_3099	1.529e-37	149.0	2E69N@1|root,330XJ@2|Bacteria,1NM8X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6345465_8	794903.OPIT5_30840	1.672e-88	308.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
ZZS2_k127_6345465_9	1396418.BATQ01000135_gene3639	1.924e-86	299.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,2ITJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
ZZS2_k127_6345465_7	1396418.BATQ01000175_gene2764	1.863e-89	304.0	COG5029@1|root,COG5029@2|Bacteria,46URI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_6345465_1	497964.CfE428DRAFT_2944	1.026e-186	604.0	COG1132@1|root,COG1132@2|Bacteria,46TV7@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_6345465_11	1191523.MROS_1090	8.577e-64	224.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
ZZS2_k127_6387420_0	497964.CfE428DRAFT_3740	2.179e-185	588.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_6387420_6	395493.BegalDRAFT_1191	9.695e-37	147.0	2D596@1|root,32TII@2|Bacteria,1N3RK@1224|Proteobacteria,1S867@1236|Gammaproteobacteria,460YQ@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6387420_1	497964.CfE428DRAFT_4253	1.084e-147	479.0	COG0523@1|root,COG0523@2|Bacteria,46URF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SRP54-type protein, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
ZZS2_k127_6387420_5	398767.Glov_0897	2.087e-63	230.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42RPM@68525|delta/epsilon subdivisions,2X5GH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
ZZS2_k127_6387420_7	671143.DAMO_1968	1.067e-19	103.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
ZZS2_k127_6387420_3	240016.ABIZ01000001_gene48	3.322e-120	399.0	COG2271@1|root,COG2271@2|Bacteria,46UJ4@74201|Verrucomicrobia,2IWFQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_6387420_2	222984.JNCS01000005_gene1526	2.214e-141	464.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,23SU2@183963|Halobacteria	183963|Halobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	aldY3	-	1.2.1.26	ko:K19588	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
ZZS2_k127_6387420_4	1123242.JH636437_gene6100	1.954e-79	274.0	COG3970@1|root,COG3970@2|Bacteria,2IWUC@203682|Planctomycetes	203682|Planctomycetes	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
ZZS2_k127_6416790_2	247634.GPB2148_80	5.073e-134	443.0	COG0738@1|root,COG0738@2|Bacteria,1R3UK@1224|Proteobacteria,1RZ2I@1236|Gammaproteobacteria,1J7JC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_6416790_0	1396418.BATQ01000063_gene1604	2.304e-198	628.0	COG0673@1|root,COG0673@2|Bacteria,46UQI@74201|Verrucomicrobia,2IVA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_6416790_5	382464.ABSI01000011_gene3111	1.226e-92	316.0	COG1108@1|root,COG1108@2|Bacteria,46VB7@74201|Verrucomicrobia,2IVRN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ABC 3 transport family	-	-	-	-	-	-	-	-	-	-	-	-	ABC-3
ZZS2_k127_6416790_1	382464.ABSI01000011_gene3112	3.727e-161	522.0	COG1108@1|root,COG1108@2|Bacteria,46TUC@74201|Verrucomicrobia,2IVI5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC-3,Fe_dep_repr_C
ZZS2_k127_6416790_3	382464.ABSI01000011_gene3114	7.234e-120	391.0	COG1121@1|root,COG1121@2|Bacteria,46T1P@74201|Verrucomicrobia,2IU80@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_6416790_6	592029.DDD_1663	2.075e-80	278.0	COG0803@1|root,COG0803@2|Bacteria,4NGMC@976|Bacteroidetes,1HWQH@117743|Flavobacteriia,3HJUM@363408|Nonlabens	976|Bacteroidetes	P	Zinc-uptake complex component A periplasmic	mntA	-	-	ko:K09815,ko:K11707	ko02010,map02010	M00242,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
ZZS2_k127_6416790_7	583355.Caka_1911	9.295e-79	273.0	COG3267@1|root,COG3267@2|Bacteria,46SXM@74201|Verrucomicrobia,3K91Q@414999|Opitutae	414999|Opitutae	U	Pfam:Arch_ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
ZZS2_k127_6416790_12	1183438.GKIL_2126	1.204e-38	153.0	COG1266@1|root,COG1266@2|Bacteria,1GFE4@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS2_k127_6416790_8	240016.ABIZ01000001_gene767	1.888e-58	222.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia,2ITXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
ZZS2_k127_6416790_10	1444712.BN1013_01684	2.192e-46	177.0	COG0290@1|root,COG0290@2|Bacteria,2JG36@204428|Chlamydiae	204428|Chlamydiae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
ZZS2_k127_6416790_4	32057.KB217478_gene2914	7.954e-98	332.0	COG0523@1|root,COG0523@2|Bacteria,1G1BG@1117|Cyanobacteria,1HKYR@1161|Nostocales	1117|Cyanobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
ZZS2_k127_6416790_11	1248760.ANFZ01000021_gene407	4.949e-46	169.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JZX4@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
ZZS2_k127_6422404_0	497964.CfE428DRAFT_0160	3.637e-210	669.0	COG1657@1|root,COG1657@2|Bacteria,46UEC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
ZZS2_k127_6422404_1	497964.CfE428DRAFT_2915	5.821e-162	525.0	COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
ZZS2_k127_6430626_3	215803.DB30_1054	8.399e-07	63.0	COG2885@1|root,COG4257@1|root,COG2885@2|Bacteria,COG4257@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF5011,HYR,OMP_b-brl,OmpA,TSP_3
ZZS2_k127_6430626_1	1396141.BATP01000056_gene3278	4.053e-55	219.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
ZZS2_k127_6430626_0	886293.Sinac_0410	1.338e-207	694.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_6430626_2	1123508.JH636439_gene1312	2.391e-47	176.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_6443740_2	159087.Daro_2348	3.895e-50	191.0	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,2VPKR@28216|Betaproteobacteria,2KX4Z@206389|Rhodocyclales	206389|Rhodocyclales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6443740_3	1121033.AUCF01000020_gene665	3.261e-43	183.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1QUUN@1224|Proteobacteria,2TX9V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Outer membrane autotransporter	-	-	-	-	-	-	-	-	-	-	-	-	PATR
ZZS2_k127_6443740_6	886293.Sinac_7034	0.0001912	48.0	COG4625@1|root,COG4625@2|Bacteria,2J0EF@203682|Planctomycetes	2|Bacteria	S	Bacterial Ig-like domain (group 3)	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,Big_3_5,Cadherin-like,Calx-beta,DUF4347,He_PIG,PATR,TIG,fn3
ZZS2_k127_6443740_4	324602.Caur_0299	1.429e-18	102.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
ZZS2_k127_6443740_1	111781.Lepto7376_0105	5.912e-64	251.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
ZZS2_k127_6443740_5	1278073.MYSTI_04388	1.995e-13	85.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,PATR,Peptidase_S74
ZZS2_k127_6443740_0	1047013.AQSP01000019_gene976	2.477e-114	390.0	COG0616@1|root,COG0616@2|Bacteria,2NNKU@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
ZZS2_k127_644395_2	497964.CfE428DRAFT_3745	6.054e-169	539.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	lytB	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
ZZS2_k127_644395_5	497964.CfE428DRAFT_5373	8.368e-135	444.0	COG0232@1|root,COG0232@2|Bacteria,46UHP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SMART metal-dependent phosphohydrolase HD region	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
ZZS2_k127_644395_11	909663.KI867150_gene1087	3.159e-68	246.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675,ko:K09684	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,MASE1,PAS,PAS_3,PAS_4,PAS_9,Peripla_BP_3,Response_reg,dCache_2
ZZS2_k127_644395_9	452637.Oter_0043	5.365e-74	256.0	COG2197@1|root,COG2197@2|Bacteria,46V5Z@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_644395_12	880072.Desac_0729	2.418e-63	235.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MQB5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
ZZS2_k127_644395_10	497964.CfE428DRAFT_4242	7.385e-73	247.0	COG0251@1|root,COG0251@2|Bacteria,46V6R@74201|Verrucomicrobia	74201|Verrucomicrobia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
ZZS2_k127_644395_4	1403819.BATR01000051_gene1500	1.726e-143	463.0	COG3616@1|root,COG3616@2|Bacteria,46TAP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
ZZS2_k127_644395_6	649747.HMPREF0083_01283	7.897e-134	439.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,26QU4@186822|Paenibacillaceae	91061|Bacilli	EG	Gluconate	gntP	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
ZZS2_k127_644395_3	1123057.P872_17755	7.835e-159	508.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,47JHU@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_644395_7	429009.Adeg_0221	1.17e-118	387.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS2_k127_644395_14	543728.Vapar_2851	3.116e-51	186.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2WBQC@28216|Betaproteobacteria,4AI59@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
ZZS2_k127_644395_15	1156937.MFUM_700141	6.038e-29	134.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,37G9U@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
ZZS2_k127_644395_1	497964.CfE428DRAFT_3584	2.59e-180	578.0	COG5441@1|root,COG5441@2|Bacteria,46U7U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
ZZS2_k127_644395_0	1444711.CCJF01000005_gene831	2.735e-234	739.0	COG0187@1|root,COG0187@2|Bacteria,2JFGD@204428|Chlamydiae	204428|Chlamydiae	L	DNA topoisomerase (ATP-hydrolyzing)	parE	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
ZZS2_k127_644395_8	880070.Cycma_3617	5.254e-96	337.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,47XPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_644395_16	452637.Oter_0299	1.14e-11	70.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6448959_3	1313172.YM304_18340	3.166e-09	59.0	COG1943@1|root,COG1943@2|Bacteria,2H8SG@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
ZZS2_k127_6448959_2	216594.MMAR_4778	1.837e-09	65.0	COG2267@1|root,COG2267@2|Bacteria,2HN3N@201174|Actinobacteria,235M5@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	bphD_1	-	3.7.1.14	ko:K05714	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R02603,R06789	RC00752,RC00753,RC01337	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS2_k127_6448959_0	1123242.JH636435_gene2024	2.589e-140	485.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8,WD40
ZZS2_k127_6448959_1	497964.CfE428DRAFT_2982	3.664e-61	220.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_6451669_2	452637.Oter_4174	3.974e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_6451669_0	497964.CfE428DRAFT_5429	2.902e-136	445.0	COG1520@1|root,COG1520@2|Bacteria,46TI7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_6451669_1	497964.CfE428DRAFT_5491	2.036e-100	332.0	COG0657@1|root,COG0657@2|Bacteria,46SVI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
ZZS2_k127_6462300_3	861299.J421_0129	2.059e-77	277.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ZZS2_k127_6462300_0	497964.CfE428DRAFT_1038	1.283e-173	560.0	28HMX@1|root,2Z7WB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6462300_1	497964.CfE428DRAFT_1037	4.379e-136	441.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	CcmA5	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_6462300_4	1396418.BATQ01000049_gene401	2.893e-31	129.0	COG3654@1|root,COG3654@2|Bacteria	2|Bacteria	-	-	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
ZZS2_k127_6462300_2	1267535.KB906767_gene5138	1.014e-97	324.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	-	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.304,2.1.1.333	ko:K13604,ko:K21460	ko00860,ko01110,map00860,map01110	-	R09063	RC00003,RC01662	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_12,Methyltransf_2,Methyltransf_25
ZZS2_k127_6462300_6	415426.Hbut_0307	0.0001934	53.0	COG1874@1|root,arCOG04085@2157|Archaea,2XPYN@28889|Crenarchaeota	28889|Crenarchaeota	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
ZZS2_k127_6471288_7	497964.CfE428DRAFT_2981	1.54e-102	341.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
ZZS2_k127_6471288_11	497964.CfE428DRAFT_2982	4.465e-76	269.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_6471288_17	497964.CfE428DRAFT_1799	1.665e-30	130.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS2_k127_6471288_10	497964.CfE428DRAFT_0115	6.398e-86	292.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS2_k127_6471288_1	1396141.BATP01000003_gene5199	2.202e-167	536.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
ZZS2_k127_6471288_16	497964.CfE428DRAFT_2283	9.115e-33	130.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS2_k127_6471288_8	1283299.AUKG01000002_gene4349	1.014e-95	324.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4CQBI@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
ZZS2_k127_6471288_18	497964.CfE428DRAFT_5372	1.774e-29	126.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
ZZS2_k127_6471288_3	215803.DB30_4326	1.43e-139	483.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YU7C@29|Myxococcales	28221|Deltaproteobacteria	KL	helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
ZZS2_k127_6471288_15	396588.Tgr7_1260	1.447e-35	143.0	COG1376@1|root,COG1376@2|Bacteria,1MYZT@1224|Proteobacteria,1S8PS@1236|Gammaproteobacteria,1WY8E@135613|Chromatiales	135613|Chromatiales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
ZZS2_k127_6471288_12	871968.DESME_06175	2.195e-49	185.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,260GE@186807|Peptococcaceae	186801|Clostridia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
ZZS2_k127_6471288_5	240016.ABIZ01000001_gene5322	7.459e-118	393.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia,2IVD4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
ZZS2_k127_6471288_9	344747.PM8797T_20129	5.17e-86	290.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_6471288_0	1131269.AQVV01000050_gene421	1.498e-180	577.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
ZZS2_k127_6471288_2	452637.Oter_2334	8.863e-167	553.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,3K73M@414999|Opitutae	414999|Opitutae	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
ZZS2_k127_6471288_21	1131269.AQVV01000050_gene416	3.538e-10	68.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
ZZS2_k127_6471288_6	1444711.CCJF01000005_gene546	2.09e-109	393.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
ZZS2_k127_6471288_20	745718.JADT01000003_gene2297	1.063e-21	112.0	COG4409@1|root,COG4409@2|Bacteria,4PM7K@976|Bacteroidetes,1IJKJ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10,fn3
ZZS2_k127_6471288_4	1232410.KI421418_gene2190	2.899e-129	421.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2WK7T@28221|Deltaproteobacteria,43SX7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS2_k127_6471288_14	398512.JQKC01000044_gene1272	1.65e-43	164.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	pipB2	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
ZZS2_k127_6471288_19	1396418.BATQ01000184_gene2636	2.907e-27	119.0	2DQ56@1|root,334T2@2|Bacteria,46WN7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4262)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4262
ZZS2_k127_6546315_5	314230.DSM3645_02158	5.71e-80	275.0	COG3119@1|root,COG3119@2|Bacteria,2IXBF@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
ZZS2_k127_6546315_8	697282.Mettu_0535	3.48e-39	156.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS2_k127_6546315_3	1173028.ANKO01000094_gene2611	8.631e-87	301.0	COG1680@1|root,COG1680@2|Bacteria,1G6GD@1117|Cyanobacteria,1HBFP@1150|Oscillatoriales	1117|Cyanobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
ZZS2_k127_6546315_6	234267.Acid_2605	4.969e-65	233.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_6546315_0	344747.PM8797T_07699	1.837e-137	449.0	COG2755@1|root,COG2755@2|Bacteria,2IWSK@203682|Planctomycetes	203682|Planctomycetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
ZZS2_k127_6546315_1	179408.Osc7112_5881	9.355e-130	460.0	COG3250@1|root,COG3250@2|Bacteria,1G4FY@1117|Cyanobacteria,1HA7W@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ZZS2_k127_6546315_4	497964.CfE428DRAFT_3712	4.242e-81	274.0	COG3576@1|root,COG3576@2|Bacteria,46SQM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
ZZS2_k127_6546315_7	1396418.BATQ01000011_gene4473	5.285e-47	175.0	COG3558@1|root,COG3558@2|Bacteria,46VBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
ZZS2_k127_6546315_2	240016.ABIZ01000001_gene2233	6.058e-94	318.0	COG0583@1|root,COG0583@2|Bacteria,46TE2@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_6551519_3	452637.Oter_2652	7.197e-27	113.0	COG0316@1|root,COG0316@2|Bacteria,46VWZ@74201|Verrucomicrobia,3K8AD@414999|Opitutae	414999|Opitutae	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
ZZS2_k127_6551519_4	478741.JAFS01000002_gene922	4.045e-23	106.0	COG1430@1|root,COG1430@2|Bacteria,46W4I@74201|Verrucomicrobia,37GW3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
ZZS2_k127_6551519_2	497964.CfE428DRAFT_1223	9.724e-33	137.0	2EMW0@1|root,33FI8@2|Bacteria,46WXX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6551519_6	395961.Cyan7425_3699	6.899e-12	78.0	COG0642@1|root,COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1G13T@1117|Cyanobacteria,3KG2A@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
ZZS2_k127_6551519_5	497964.CfE428DRAFT_5353	7.254e-23	113.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
ZZS2_k127_6551519_0	420324.KI911938_gene9	8.909e-178	579.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,1JXMK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
ZZS2_k127_6551519_1	240016.ABIZ01000001_gene3247	1.421e-137	446.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,2IU5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS2_k127_656588_2	1396418.BATQ01000131_gene3954	3.002e-05	48.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_656588_0	1123242.JH636435_gene2487	1.772e-80	298.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_656588_1	886293.Sinac_6489	1.174e-79	291.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_6573712_12	1396418.BATQ01000091_gene5770	5.528e-22	110.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3204@1|root,COG3291@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
ZZS2_k127_6573712_20	313628.LNTAR_06534	3.332e-05	56.0	COG3211@1|root,COG3211@2|Bacteria	2|Bacteria	O	Phosphatase	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_6573712_19	518766.Rmar_2392	1.851e-05	59.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6573712_14	292459.STH1184	4.198e-13	84.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1VNAP@1239|Firmicutes,24W68@186801|Clostridia	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_6573712_10	1392490.JHZX01000001_gene383	3.779e-34	154.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1HY9Y@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
ZZS2_k127_6573712_18	661367.LLO_1892	3.556e-06	61.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
ZZS2_k127_6573712_8	1121937.AUHJ01000001_gene558	4.616e-43	163.0	COG0563@1|root,COG0563@2|Bacteria,1REQW@1224|Proteobacteria,1S67T@1236|Gammaproteobacteria,466VT@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	COG0563 Adenylate kinase and related kinases	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
ZZS2_k127_6573712_0	861299.J421_1753	2.146e-272	880.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_6573712_7	290512.Paes_2385	2.538e-51	192.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_6573712_5	518766.Rmar_1759	2.477e-60	233.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1FK07@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
ZZS2_k127_6573712_15	1120950.KB892707_gene4726	8.201e-09	69.0	COG3664@1|root,COG3664@2|Bacteria,2IAP4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_cc
ZZS2_k127_6573712_4	1340493.JNIF01000003_gene2695	5.361e-69	254.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6573712_9	1026882.MAMP_01900	2.009e-41	175.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	PATR
ZZS2_k127_6573712_6	1123242.JH636434_gene4817	1.929e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,2IZF6@203682|Planctomycetes	2|Bacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6573712_11	344747.PM8797T_21508	2.994e-26	125.0	COG1680@1|root,COG1680@2|Bacteria,2IZJ2@203682|Planctomycetes	203682|Planctomycetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6573712_3	497964.CfE428DRAFT_2280	6.117e-94	330.0	COG1680@1|root,COG1680@2|Bacteria,46SS8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_6573712_17	1122929.KB908217_gene153	1.182e-06	55.0	2DPXH@1|root,333TM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6573712_13	1121920.AUAU01000004_gene641	1.166e-14	78.0	COG1770@1|root,COG1770@2|Bacteria,3Y3PK@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9A, prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
ZZS2_k127_6573712_1	452637.Oter_3899	1.729e-226	716.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46UA9@74201|Verrucomicrobia,3K7MZ@414999|Opitutae	414999|Opitutae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
ZZS2_k127_6573712_16	66373.JOFQ01000001_gene1550	7.014e-08	63.0	COG3386@1|root,COG3386@2|Bacteria,2I399@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6575235_6	1380394.JADL01000002_gene1277	2.258e-92	326.0	COG1874@1|root,COG1874@2|Bacteria,1R702@1224|Proteobacteria,2U2UI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Beta-agarase	-	-	3.2.1.81	ko:K01219	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_42
ZZS2_k127_6575235_8	349741.Amuc_1517	1.944e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_6575235_7	452637.Oter_0358	1.306e-72	277.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46YZC@74201|Verrucomicrobia,3K9WB@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_6575235_9	76114.ebA6732	6.592e-22	103.0	2DP2V@1|root,330AH@2|Bacteria,1R3EE@1224|Proteobacteria,2VUJY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
ZZS2_k127_6575235_4	1396141.BATP01000020_gene19	7.899e-155	501.0	COG2271@1|root,COG2271@2|Bacteria,46U29@74201|Verrucomicrobia,2IV9J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_6575235_2	886293.Sinac_0938	2.125e-187	594.0	COG2960@1|root,COG2960@2|Bacteria,2IX54@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_6575235_1	1403819.BATR01000059_gene1839	2.288e-218	704.0	COG3258@1|root,COG3258@2|Bacteria,46UEX@74201|Verrucomicrobia,2IVJP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PA14,PSCyt3,PSD4,PSD5
ZZS2_k127_6575235_5	1396418.BATQ01000050_gene302	1.157e-154	502.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria	2|Bacteria	M	metalloendopeptidase activity	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
ZZS2_k127_6575235_16	342113.DM82_6232	3.048e-07	60.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria,2W531@28216|Betaproteobacteria,1KAFV@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS2_k127_6575235_15	1336803.PHEL49_1008	9.88e-08	61.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes,1I33Z@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6575235_18	405948.SACE_6309	7.015e-06	53.0	COG0412@1|root,COG0412@2|Bacteria,2I37P@201174|Actinobacteria,4EF9X@85010|Pseudonocardiales	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
ZZS2_k127_6575235_12	243365.CV_3467	3.417e-13	77.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KU3E@206351|Neisseriales	206351|Neisseriales	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
ZZS2_k127_6575235_17	382464.ABSI01000006_gene842	1.348e-06	59.0	COG0841@1|root,COG0841@2|Bacteria,46U7C@74201|Verrucomicrobia,2IVDR@203494|Verrucomicrobiae	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_6575235_10	886293.Sinac_4035	4.491e-20	105.0	COG3210@1|root,COG4655@1|root,COG3210@2|Bacteria,COG4655@2|Bacteria,2J30Y@203682|Planctomycetes	203682|Planctomycetes	U	Extracellular nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
ZZS2_k127_6575235_19	330214.NIDE3859	6.318e-05	45.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS2_k127_6575235_13	243159.AFE_1816	9.26e-10	63.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,2NC9Q@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS2_k127_6575235_3	258533.BN977_05832	4.247e-163	527.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,23D4U@1762|Mycobacteriaceae	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
ZZS2_k127_6575235_0	1163617.SCD_n00861	0.0	1146.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
ZZS2_k127_6575235_14	46234.ANA_C11949	1.397e-08	59.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1G2E2@1117|Cyanobacteria,1HINK@1161|Nostocales	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
ZZS2_k127_6575235_11	251229.Chro_4406	6.598e-19	89.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,3VJ02@52604|Pleurocapsales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS2_k127_6590517_7	237368.SCABRO_02917	0.0001847	45.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
ZZS2_k127_6590517_5	1296415.JACC01000059_gene1025	3.847e-17	98.0	COG1874@1|root,COG3291@1|root,COG3420@1|root,COG3897@1|root,COG4257@1|root,COG4886@1|root,COG1874@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,COG4257@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1IKV6@117743|Flavobacteriia,2YJTU@290174|Aquimarina	976|Bacteroidetes	G	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5011,Laminin_G_3
ZZS2_k127_6590517_3	1121481.AUAS01000006_gene877	1.942e-45	192.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
ZZS2_k127_6590517_4	1195236.CTER_1597	2.662e-33	137.0	COG2273@1|root,COG3325@1|root,COG2273@2|Bacteria,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,DUF4849,Glyco_hydro_16
ZZS2_k127_6590517_2	452637.Oter_3515	6.346e-67	247.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia,3K9I6@414999|Opitutae	414999|Opitutae	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS2_k127_6590517_0	382464.ABSI01000010_gene3213	8.943e-152	492.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_6590517_6	1123052.AUDF01000005_gene1005	1.415e-10	69.0	COG2246@1|root,COG2246@2|Bacteria,2GZM8@201174|Actinobacteria,4FQPC@85023|Microbacteriaceae	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
ZZS2_k127_6590517_1	1210884.HG799462_gene8336	5.964e-116	394.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_6607810_1	1379698.RBG1_1C00001G0194	8.864e-39	154.0	COG3211@1|root,COG3540@1|root,COG3211@2|Bacteria,COG3540@2|Bacteria,2NS16@2323|unclassified Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoX	-	3.1.3.1	ko:K01113,ko:K07093	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF839
ZZS2_k127_6607810_3	926566.Terro_1100	5.466e-06	51.0	COG2271@1|root,COG2271@2|Bacteria,3Y47N@57723|Acidobacteria,2JKTK@204432|Acidobacteriia	204432|Acidobacteriia	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
ZZS2_k127_6607810_0	163908.KB235896_gene629	3.509e-57	214.0	2DBUK@1|root,2ZB6C@2|Bacteria,1GFM7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6628839_4	1121920.AUAU01000009_gene1881	1.518e-14	87.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_6628839_7	497964.CfE428DRAFT_5265	0.0003248	47.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6628839_3	509635.N824_07835	8.038e-35	142.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes,1IUNH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
ZZS2_k127_6628839_0	344747.PM8797T_13233	9.059e-134	440.0	COG1524@1|root,COG1524@2|Bacteria,2J26J@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS2_k127_6628839_5	269798.CHU_1075	1.917e-12	79.0	COG3405@1|root,COG3405@2|Bacteria,4PKQF@976|Bacteroidetes,47S4W@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl hydrolases family 8	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,Glyco_hydro_8
ZZS2_k127_6628839_1	240016.ABIZ01000001_gene1288	1.934e-71	246.0	COG0662@1|root,COG0662@2|Bacteria,46V2V@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_6628839_6	1122931.AUAE01000007_gene1162	1.119e-10	62.0	COG1434@1|root,COG1470@1|root,COG1434@2|Bacteria,COG1470@2|Bacteria,4NE96@976|Bacteroidetes,2FR8X@200643|Bacteroidia,22ZBD@171551|Porphyromonadaceae	976|Bacteroidetes	S	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
ZZS2_k127_6639461_13	1183438.GKIL_4381	4.431e-51	200.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein,Peptidase_S8,VCBS
ZZS2_k127_6639461_11	1303518.CCALI_00699	6.535e-66	239.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
ZZS2_k127_6639461_4	240016.ABIZ01000001_gene1488	5.855e-130	427.0	28JXN@1|root,2Z9N3@2|Bacteria,46U4R@74201|Verrucomicrobia,2IV1Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_6639461_5	1123248.KB893325_gene1170	1.399e-118	389.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1INUU@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydroxypyruvate isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_6639461_15	589865.DaAHT2_0739	2.687e-36	146.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MKSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
ZZS2_k127_6639461_7	452637.Oter_2551	1.186e-101	344.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
ZZS2_k127_6639461_9	452637.Oter_2550	1.891e-90	303.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_6639461_10	452637.Oter_2549	1.349e-69	244.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
ZZS2_k127_6639461_3	497964.CfE428DRAFT_2917	1.427e-152	496.0	COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
ZZS2_k127_6639461_12	1396141.BATP01000021_gene148	1.248e-64	226.0	COG0229@1|root,COG0229@2|Bacteria,46TM8@74201|Verrucomicrobia,2IUM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	SelR domain	-	-	-	-	-	-	-	-	-	-	-	-	SelR
ZZS2_k127_6639461_14	28229.ND2E_0431	1.798e-43	183.0	COG2340@1|root,COG2931@1|root,COG3227@1|root,COG4932@1|root,COG5644@1|root,COG2340@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2Q7GE@267889|Colwelliaceae	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Big_3_2,Cadherin_3,Calx-beta,He_PIG,HemolysinCabind,OmpA_membrane,RTX,RTX_C,VWA_2,fn3
ZZS2_k127_6639461_8	240016.ABIZ01000001_gene2859	3.098e-97	336.0	COG0477@1|root,COG2814@2|Bacteria,46V8K@74201|Verrucomicrobia,2IUV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
ZZS2_k127_6639461_2	504472.Slin_0803	2.776e-167	542.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47UQJ@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
ZZS2_k127_6639461_6	497964.CfE428DRAFT_4923	9.007e-103	357.0	COG0583@1|root,COG0583@2|Bacteria,46SDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_6639461_0	1173024.KI912153_gene315	0.0	1317.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1JIBX@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
ZZS2_k127_6639461_1	700598.Niako_0762	1.026e-234	744.0	COG5297@1|root,COG5297@2|Bacteria,4PKPX@976|Bacteroidetes,1IV41@117747|Sphingobacteriia	976|Bacteroidetes	G	Fg-gap repeat	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
ZZS2_k127_6643444_2	886293.Sinac_4629	8.496e-149	486.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_6643444_1	240016.ABIZ01000001_gene2537	1.374e-210	662.0	COG1413@1|root,COG1413@2|Bacteria,46SU9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_6643444_0	497964.CfE428DRAFT_1447	0.0	1206.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
ZZS2_k127_6643444_4	215803.DB30_0733	1.499e-26	111.0	COG2840@1|root,COG2840@2|Bacteria,1QX48@1224|Proteobacteria,43BWQ@68525|delta/epsilon subdivisions,2X77I@28221|Deltaproteobacteria,2Z3DP@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
ZZS2_k127_6643444_3	1396141.BATP01000060_gene4748	1.03e-32	131.0	COG0727@1|root,COG0727@2|Bacteria,46W4U@74201|Verrucomicrobia,2IUJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
ZZS2_k127_6645022_9	667015.Bacsa_0757	0.0001957	54.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,2FMJ3@200643|Bacteroidia,4AK64@815|Bacteroidaceae	976|Bacteroidetes	V	Psort location CytoplasmicMembrane, score 10.00	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
ZZS2_k127_6645022_7	1210884.HG799464_gene11092	1.213e-14	87.0	COG1668@1|root,COG1668@2|Bacteria,2IXFE@203682|Planctomycetes	203682|Planctomycetes	CP	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
ZZS2_k127_6645022_8	679200.HMPREF9333_00914	1.561e-08	67.0	COG1277@1|root,COG1277@2|Bacteria,1V90F@1239|Firmicutes,25DFP@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
ZZS2_k127_6645022_4	278957.ABEA03000094_gene4651	8.068e-45	178.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,3K762@414999|Opitutae	414999|Opitutae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS2_k127_6645022_2	497964.CfE428DRAFT_6209	2.904e-147	491.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3,OmpA
ZZS2_k127_6645022_0	1403819.BATR01000102_gene3389	1.092e-290	927.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,COG3828@2|Bacteria,46TYQ@74201|Verrucomicrobia,2IU00@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,F5_F8_type_C,ThuA
ZZS2_k127_6645022_5	497964.CfE428DRAFT_6314	1.953e-24	108.0	2E63P@1|root,330SQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6645022_6	1353531.AZNX01000014_gene3221	3.536e-21	107.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS2_k127_6645022_1	497964.CfE428DRAFT_3817	1.422e-190	611.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
ZZS2_k127_6645022_3	1121904.ARBP01000017_gene5071	1.201e-50	196.0	COG1028@1|root,COG1520@1|root,COG3405@1|root,COG5297@1|root,COG1028@2|Bacteria,COG1520@2|Bacteria,COG3405@2|Bacteria,COG5297@2|Bacteria,4NUJD@976|Bacteroidetes	976|Bacteroidetes	IQ	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6646945_2	886293.Sinac_6003	5.35e-132	436.0	COG4102@1|root,COG4102@2|Bacteria,2IYN0@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_6646945_0	1123508.JH636439_gene1121	1.637e-145	490.0	COG4654@1|root,COG4654@2|Bacteria,2IYSS@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_6646945_9	756272.Plabr_4351	3.786e-27	121.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
ZZS2_k127_6646945_10	742733.HMPREF9469_03254	0.000972	51.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,24K2H@186801|Clostridia,221ED@1506553|Lachnoclostridium	186801|Clostridia	S	leucine-rich repeat-containing protein typical subtype	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CW_binding_2,DUF3888,GA-like,LRR_4,LRR_6,LRR_8
ZZS2_k127_6646945_3	243231.GSU2816	4.963e-110	392.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_6646945_1	661478.OP10G_1068	6.18e-140	455.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
ZZS2_k127_6646945_8	163908.KB235896_gene2229	1.928e-49	202.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G02E@1117|Cyanobacteria	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
ZZS2_k127_6646945_4	1499967.BAYZ01000068_gene1935	2.301e-98	346.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
ZZS2_k127_6646945_7	497964.CfE428DRAFT_0545	1.132e-53	198.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6646945_5	1123242.JH636435_gene2487	9.601e-97	343.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_6646945_6	1211114.ALIP01000112_gene1798	7.239e-90	315.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
ZZS2_k127_6654206_3	452637.Oter_0242	2.213e-49	183.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS2_k127_6654206_7	643473.KB235930_gene804	0.0001362	52.0	COG0848@1|root,COG0848@2|Bacteria,1G71E@1117|Cyanobacteria,1HNH7@1161|Nostocales	1117|Cyanobacteria	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_6654206_0	497964.CfE428DRAFT_1886	9.662e-136	445.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS2_k127_6654206_1	497964.CfE428DRAFT_4568	1.222e-125	417.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6654206_2	1278073.MYSTI_07350	2.503e-70	252.0	COG3358@1|root,COG3358@2|Bacteria,1RBIA@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
ZZS2_k127_6654206_6	1121921.KB898711_gene1998	0.0001225	52.0	COG0421@1|root,COG0421@2|Bacteria,1QWZZ@1224|Proteobacteria,1T31M@1236|Gammaproteobacteria,2PNTX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_6654206_4	1193181.BN10_1300016	1.239e-12	70.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6654206_5	1191299.AJYX01000045_gene214	2.294e-09	58.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,1SDC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6654964_0	530564.Psta_0688	7.544e-160	516.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6654964_2	1242864.D187_008109	6.411e-123	402.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
ZZS2_k127_6654964_1	886293.Sinac_0671	1.029e-137	451.0	COG0329@1|root,COG0329@2|Bacteria,2IXEF@203682|Planctomycetes	203682|Planctomycetes	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
ZZS2_k127_6654964_3	314230.DSM3645_26734	1.07e-111	371.0	COG0451@1|root,COG0451@2|Bacteria,2IXGI@203682|Planctomycetes	203682|Planctomycetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ZZS2_k127_6658317_4	639282.DEFDS_1937	3.276e-15	79.0	COG2897@1|root,COG2897@2|Bacteria,2GF0G@200930|Deferribacteres	200930|Deferribacteres	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_6658317_3	1121405.dsmv_3549	1.592e-17	89.0	COG2259@1|root,COG2259@2|Bacteria,1NC5I@1224|Proteobacteria,42V27@68525|delta/epsilon subdivisions,2WS2G@28221|Deltaproteobacteria,2MPU2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	MauE
ZZS2_k127_6658317_0	497964.CfE428DRAFT_2425	0.0	1397.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U71@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
ZZS2_k127_6658317_2	234267.Acid_5332	2.884e-190	615.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_6658317_1	886293.Sinac_7042	1.479e-217	700.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
ZZS2_k127_6663070_2	497964.CfE428DRAFT_2614	1.51e-100	338.0	COG4989@1|root,COG4989@2|Bacteria,46SU2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS2_k127_6663070_1	497964.CfE428DRAFT_2962	3.63e-135	438.0	COG2957@1|root,COG2957@2|Bacteria,46SAM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
ZZS2_k127_6663070_6	671143.DAMO_2617	2.959e-26	115.0	COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
ZZS2_k127_6663070_3	497964.CfE428DRAFT_6695	2.637e-52	191.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
ZZS2_k127_6663070_0	497964.CfE428DRAFT_2672	2.727e-232	728.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
ZZS2_k127_6663070_4	1121396.KB893074_gene3027	4.42e-30	127.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,42TZW@68525|delta/epsilon subdivisions,2WNUV@28221|Deltaproteobacteria,2MMRU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
ZZS2_k127_6663070_7	1121378.KB899707_gene1380	0.0006002	53.0	COG3525@1|root,COG3525@2|Bacteria,1WM65@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
ZZS2_k127_6663070_5	1123242.JH636435_gene2929	3.628e-28	133.0	COG0526@1|root,COG2373@1|root,COG4219@1|root,COG0526@2|Bacteria,COG2373@2|Bacteria,COG4219@2|Bacteria,2J12A@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
ZZS2_k127_6663663_5	1396141.BATP01000025_gene980	3.017e-05	46.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_6663663_4	1210884.HG799465_gene11554	2.814e-13	71.0	2EKJP@1|root,33E9H@2|Bacteria	2|Bacteria	S	Rdx family	-	-	-	-	-	-	-	-	-	-	-	-	Rdx
ZZS2_k127_6663663_2	330214.NIDE0276	2.725e-83	285.0	COG3264@1|root,COG3264@2|Bacteria,3J0R7@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
ZZS2_k127_6663663_1	497964.CfE428DRAFT_1935	1.625e-117	393.0	COG2870@1|root,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,Hydrolase,PfkB
ZZS2_k127_6663663_0	886293.Sinac_0542	2.127e-162	520.0	COG1915@1|root,COG1915@2|Bacteria,2IXX9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6663663_3	324602.Caur_0299	5.869e-25	121.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
ZZS2_k127_6669881_2	859657.RPSI07_2738	4.786e-24	111.0	2E4Z6@1|root,32ZSW@2|Bacteria,1N6U2@1224|Proteobacteria,2VW9R@28216|Betaproteobacteria,1KB0H@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6669881_0	1122604.JONR01000010_gene3879	5.576e-60	218.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X42D@135614|Xanthomonadales	135614|Xanthomonadales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ZZS2_k127_6669881_3	457570.Nther_0978	2.493e-05	53.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	rnfG	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0009279,GO:0016020,GO:0016491,GO:0016651,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0055114,GO:0071944	-	ko:K03612,ko:K03613,ko:K21559	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind
ZZS2_k127_6669881_1	1403819.BATR01000123_gene4356	1.766e-48	184.0	28KDQ@1|root,2ZA05@2|Bacteria,46VJS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_18	498211.CJA_0127	4.803e-81	301.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
ZZS2_k127_6675004_38	335543.Sfum_0949	6.818e-11	74.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PPF@68525|delta/epsilon subdivisions,2WM3K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_42	1116472.MGMO_57c00180	2.847e-06	57.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,1R1H9@1224|Proteobacteria,1T52V@1236|Gammaproteobacteria,1XEUH@135618|Methylococcales	135618|Methylococcales	EH	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD,fn3
ZZS2_k127_6675004_7	794903.OPIT5_23495	8.716e-157	502.0	COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia,3K7FF@414999|Opitutae	414999|Opitutae	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
ZZS2_k127_6675004_19	497964.CfE428DRAFT_3483	8.261e-76	260.0	COG4445@1|root,COG4445@2|Bacteria	2|Bacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
ZZS2_k127_6675004_33	247490.KSU1_C1333	7.491e-15	86.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_6675004_4	497964.CfE428DRAFT_1743	1.015e-266	835.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
ZZS2_k127_6675004_20	1430331.EP10_18360	6.853e-69	243.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
ZZS2_k127_6675004_30	1121472.AQWN01000010_gene571	2.324e-26	115.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,262EI@186807|Peptococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
ZZS2_k127_6675004_13	452637.Oter_0497	1.738e-108	364.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_6675004_41	497964.CfE428DRAFT_0255	7.673e-07	59.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K03406,ko:K07675,ko:K13598	ko02020,ko02030,map02020,map02030	M00473,M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,MCPsignal,PAS,PAS_4,PAS_9,dCache_1
ZZS2_k127_6675004_0	765911.Thivi_2556	0.0	3184.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1WXFY@135613|Chromatiales	135613|Chromatiales	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
ZZS2_k127_6675004_37	1041139.KB902646_gene3385	6.575e-11	68.0	2E36Z@1|root,32Y6R@2|Bacteria,1NCM6@1224|Proteobacteria,2UGU3@28211|Alphaproteobacteria,4BG2C@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_10	204669.Acid345_2863	1.539e-117	389.0	COG3285@1|root,COG3285@2|Bacteria,3Y637@57723|Acidobacteria,2JM9H@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
ZZS2_k127_6675004_14	1123257.AUFV01000003_gene1268	4.61e-99	330.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S3J8@1236|Gammaproteobacteria,1XC9E@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2238
ZZS2_k127_6675004_15	497964.CfE428DRAFT_4309	1.304e-95	328.0	COG1793@1|root,COG1793@2|Bacteria,46S9X@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS2_k127_6675004_22	452637.Oter_4309	1.396e-57	207.0	COG1793@1|root,COG1793@2|Bacteria,46S9X@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS2_k127_6675004_12	1396418.BATQ01000119_gene3117	7.866e-109	362.0	COG1273@1|root,COG1273@2|Bacteria,46SB0@74201|Verrucomicrobia,2IVP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Ku70/Ku80 beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Ku
ZZS2_k127_6675004_28	700598.Niako_2063	3.04e-31	126.0	2B7KW@1|root,320RZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_39	42256.RradSPS_2097	5.233e-08	59.0	290MR@1|root,2ZNA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
ZZS2_k127_6675004_31	1192034.CAP_1556	2.608e-19	98.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S1C family	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_6675004_34	1005048.CFU_0304	1.577e-13	80.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,2VT3J@28216|Betaproteobacteria,474JG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
ZZS2_k127_6675004_17	317936.Nos7107_4332	2.945e-90	309.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1HM81@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM YihY family protein (not ribonuclease BN)	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ZZS2_k127_6675004_26	880070.Cycma_4412	5.943e-36	151.0	COG2982@1|root,COG2982@2|Bacteria,4NIE2@976|Bacteroidetes,47M87@768503|Cytophagia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
ZZS2_k127_6675004_2	1396418.BATQ01000050_gene289	0.0	1287.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,46SI7@74201|Verrucomicrobia,2IV43@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
ZZS2_k127_6675004_1	497964.CfE428DRAFT_1952	0.0	2274.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG3605@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,46Z8Q@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
ZZS2_k127_6675004_16	1242864.D187_004522	2.113e-90	311.0	COG0642@1|root,COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X791@28221|Deltaproteobacteria,2YUF6@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_6675004_6	452637.Oter_1135	2.626e-157	525.0	COG0784@1|root,COG3437@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,46Z3U@74201|Verrucomicrobia,3KA3G@414999|Opitutae	74201|Verrucomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_6675004_36	1500897.JQNA01000002_gene5297	5.505e-11	75.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,2W1NC@28216|Betaproteobacteria,1K3PG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM PRC-barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PRC
ZZS2_k127_6675004_35	1281779.H009_02888	4.154e-11	75.0	COG3861@1|root,COG3861@2|Bacteria,1MZM2@1224|Proteobacteria,2UBTQ@28211|Alphaproteobacteria,4BKWP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	PRC-barrel domain	MA20_07315	-	-	-	-	-	-	-	-	-	-	-	PRC
ZZS2_k127_6675004_32	264201.pc1171	6.926e-19	100.0	COG2823@1|root,COG2823@2|Bacteria,2JGHK@204428|Chlamydiae	204428|Chlamydiae	S	BON domain	osmY	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS2_k127_6675004_21	697282.Mettu_0550	8.642e-64	223.0	COG3861@1|root,COG3861@2|Bacteria,1QVGH@1224|Proteobacteria,1RP36@1236|Gammaproteobacteria,1XF2D@135618|Methylococcales	135618|Methylococcales	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_24	1403819.BATR01000114_gene3952	1.454e-44	166.0	COG0346@1|root,COG0346@2|Bacteria,46VWA@74201|Verrucomicrobia,2IVZP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_6675004_27	864069.MicloDRAFT_00008250	3.388e-35	142.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
ZZS2_k127_6675004_23	28072.Nos7524_3025	4.816e-53	194.0	COG0778@1|root,COG0778@2|Bacteria,1G4SQ@1117|Cyanobacteria,1HQ49@1161|Nostocales	1117|Cyanobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
ZZS2_k127_6675004_29	290397.Adeh_0959	1.574e-30	123.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,433SU@68525|delta/epsilon subdivisions,2WY45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_25	56110.Oscil6304_1013	7.396e-37	146.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
ZZS2_k127_6675004_3	649638.Trad_0897	0.0	1081.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
ZZS2_k127_6675004_8	502025.Hoch_4995	1.987e-120	399.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2Z2W5@29|Myxococcales	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS2_k127_6675004_40	1122176.KB903540_gene58	1.797e-07	63.0	28M5H@1|root,2ZAJ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6675004_5	1396141.BATP01000038_gene1203	9.687e-171	546.0	COG1262@1|root,COG1262@2|Bacteria,46SPX@74201|Verrucomicrobia,2IV38@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_6675004_9	452637.Oter_3025	4.008e-120	392.0	COG0684@1|root,COG0684@2|Bacteria,46VAD@74201|Verrucomicrobia,3K8HM@414999|Opitutae	414999|Opitutae	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ZZS2_k127_6675004_11	1123508.JH636450_gene7084	4.308e-116	381.0	COG3828@1|root,COG3828@2|Bacteria,2IX0E@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,ThuA
ZZS2_k127_6684275_10	530564.Psta_0083	2.672e-88	298.0	COG0500@1|root,COG2226@2|Bacteria,2IYU3@203682|Planctomycetes	203682|Planctomycetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_6684275_15	1173029.JH980292_gene1498	1.856e-19	98.0	COG0457@1|root,COG0457@2|Bacteria,1G5P9@1117|Cyanobacteria,1HB1F@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
ZZS2_k127_6684275_8	251221.35213668	3.699e-107	364.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_6684275_7	869210.Marky_0618	5.285e-109	368.0	COG0508@1|root,COG0508@2|Bacteria,1WI1G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS2_k127_6684275_1	344747.PM8797T_25801	1.961e-161	522.0	COG1249@1|root,COG1249@2|Bacteria,2IX5H@203682|Planctomycetes	203682|Planctomycetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS2_k127_6684275_13	1380394.JADL01000012_gene992	5.321e-56	210.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,2JRFY@204441|Rhodospirillales	204441|Rhodospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS2_k127_6684275_12	1286106.MPL1_00897	9.44e-60	215.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,462Q4@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6684275_4	234267.Acid_3896	3.248e-126	416.0	COG1454@1|root,COG1454@2|Bacteria,3Y575@57723|Acidobacteria	57723|Acidobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
ZZS2_k127_6684275_14	1499967.BAYZ01000118_gene3301	2.064e-45	166.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
ZZS2_k127_6684275_3	240016.ABIZ01000001_gene4800	5.293e-141	460.0	COG1520@1|root,COG1520@2|Bacteria,46TM3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_6684275_0	1121904.ARBP01000026_gene688	1.304e-163	520.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,47NU3@768503|Cytophagia	976|Bacteroidetes	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
ZZS2_k127_6684275_9	1227739.Hsw_1365	3.275e-97	325.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,47N6W@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
ZZS2_k127_6684275_5	1403819.BATR01000150_gene5081	3.004e-122	397.0	COG4821@1|root,COG4821@2|Bacteria,46XIJ@74201|Verrucomicrobia,2IW0K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
ZZS2_k127_6684275_6	240016.ABIZ01000001_gene980	9.662e-121	408.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DHHA1 domain	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS2_k127_6684275_11	1521187.JPIM01000037_gene3876	4.29e-87	299.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
ZZS2_k127_6684275_2	278957.ABEA03000041_gene2093	2.329e-143	475.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
ZZS2_k127_6689600_25	653948.CCA17500	8.829e-07	59.0	COG0457@1|root,KOG0553@2759|Eukaryota	2759|Eukaryota	O	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	SGTB	GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006605,GO:0006612,GO:0006620,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006996,GO:0007029,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010604,GO:0010605,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0019222,GO:0019538,GO:0019941,GO:0030162,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031330,GO:0031331,GO:0031333,GO:0032268,GO:0032269,GO:0032270,GO:0032434,GO:0032435,GO:0032436,GO:0032459,GO:0032460,GO:0032947,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0034976,GO:0036503,GO:0042176,GO:0042177,GO:0042221,GO:0042802,GO:0042803,GO:0042886,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043621,GO:0043632,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044877,GO:0045047,GO:0045048,GO:0045184,GO:0045732,GO:0045861,GO:0045862,GO:0046907,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051205,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051603,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0061024,GO:0061136,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071816,GO:0071840,GO:0072379,GO:0072380,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901799,GO:1901800,GO:1903050,GO:1903051,GO:1903052,GO:1903069,GO:1903070,GO:1903071,GO:1903332,GO:1903334,GO:1903362,GO:1903363,GO:1903364,GO:1903573,GO:1903644,GO:1903646,GO:1904288,GO:1904292,GO:1904293,GO:1904294,GO:1905897,GO:1905898,GO:2000058,GO:2000059,GO:2000060	-	ko:K16365	-	-	-	-	ko00000,ko04147,ko04516	-	-	-	SGTA_dimer,TPR_1,TPR_11,TPR_2,TPR_8
ZZS2_k127_6689600_7	1499967.BAYZ01000093_gene4011	1.871e-151	486.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
ZZS2_k127_6689600_22	1337936.IJ00_09305	4.387e-33	133.0	COG0454@1|root,COG0454@2|Bacteria,1G5EA@1117|Cyanobacteria,1HSMP@1161|Nostocales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
ZZS2_k127_6689600_26	926692.AZYG01000040_gene1449	1.247e-05	58.0	COG3642@1|root,COG3642@2|Bacteria,1VNEA@1239|Firmicutes,250HK@186801|Clostridia,3WBND@53433|Halanaerobiales	186801|Clostridia	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
ZZS2_k127_6689600_9	497964.CfE428DRAFT_5037	5.719e-147	475.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
ZZS2_k127_6689600_0	497964.CfE428DRAFT_5035	5.52e-252	783.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
ZZS2_k127_6689600_5	497964.CfE428DRAFT_5033	4.183e-206	644.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6689600_3	497964.CfE428DRAFT_5031	2.371e-224	708.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_6689600_4	497964.CfE428DRAFT_5030	2.499e-214	690.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_6689600_20	497964.CfE428DRAFT_5029	3.632e-61	237.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
ZZS2_k127_6689600_21	497964.CfE428DRAFT_5028	2.592e-42	162.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K06075,ko:K22296	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
ZZS2_k127_6689600_17	314230.DSM3645_11417	6.435e-69	247.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
ZZS2_k127_6689600_12	497964.CfE428DRAFT_0775	2.474e-127	415.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_6689600_6	886293.Sinac_0405	3.779e-156	498.0	COG0714@1|root,COG0714@2|Bacteria,2IX8Y@203682|Planctomycetes	203682|Planctomycetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_6689600_13	497964.CfE428DRAFT_0773	6.847e-107	354.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
ZZS2_k127_6689600_2	497964.CfE428DRAFT_0772	2.093e-238	765.0	COG0457@1|root,COG0457@2|Bacteria,46U9B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
ZZS2_k127_6689600_23	75379.Tint_0155	3.861e-30	128.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2VRXW@28216|Betaproteobacteria,1KPH1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	LysE type translocator	rhtB_2	-	-	ko:K05834	-	-	-	-	ko00000,ko02000	2.A.76.1.1	-	-	LysE
ZZS2_k127_6689600_16	639282.DEFDS_1661	2.189e-77	265.0	COG0217@1|root,COG0217@2|Bacteria,2GEK9@200930|Deferribacteres	200930|Deferribacteres	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
ZZS2_k127_6689600_11	478741.JAFS01000002_gene955	1.502e-127	442.0	COG1033@1|root,COG1033@2|Bacteria,46Z86@74201|Verrucomicrobia,37G0Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
ZZS2_k127_6689600_8	497964.CfE428DRAFT_1506	1.865e-149	484.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
ZZS2_k127_6689600_19	338963.Pcar_2691	4.237e-63	228.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WM9R@28221|Deltaproteobacteria,43S3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Putative RNA methylase family UPF0020	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
ZZS2_k127_6689600_24	1112212.JH584235_gene545	2.581e-12	72.0	2DZJF@1|root,32VCA@2|Bacteria,1P0DA@1224|Proteobacteria,2UUTF@28211|Alphaproteobacteria,2K5RC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6689600_14	1123508.JH636442_gene4015	1.688e-103	354.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_6689600_10	452637.Oter_1003	1.584e-137	449.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
ZZS2_k127_6689600_1	382464.ABSI01000021_gene419	9.052e-241	757.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
ZZS2_k127_6689600_18	1121472.AQWN01000002_gene2274	8.485e-65	227.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,260M0@186807|Peptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS2_k127_6689600_15	880073.Calab_2031	4.364e-79	272.0	COG0796@1|root,COG0796@2|Bacteria,2NP3D@2323|unclassified Bacteria	2|Bacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
ZZS2_k127_6689600_28	215803.DB30_6050	0.0009561	48.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2YVBP@29|Myxococcales	28221|Deltaproteobacteria	M	polysaccharide export	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS2_k127_6689600_27	1121920.AUAU01000018_gene1776	1.248e-05	50.0	COG0405@1|root,COG0405@2|Bacteria,3Y2I7@57723|Acidobacteria	57723|Acidobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS2_k127_6699121_0	1396141.BATP01000034_gene4198	6.587e-20	104.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_6699121_1	7918.ENSLOCP00000016626	8.497e-09	68.0	KOG4221@1|root,KOG4221@2759|Eukaryota,39JY7@33154|Opisthokonta,3BC0X@33208|Metazoa,3CYFQ@33213|Bilateria,48376@7711|Chordata,492V0@7742|Vertebrata,49S38@7898|Actinopterygii	33208|Metazoa	T	Protogenin	PRTG	GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008150,GO:0008582,GO:0009987,GO:0010721,GO:0016020,GO:0016043,GO:0016322,GO:0021700,GO:0022008,GO:0022607,GO:0023052,GO:0030154,GO:0030182,GO:0030424,GO:0030425,GO:0032501,GO:0032502,GO:0036477,GO:0038023,GO:0040008,GO:0042551,GO:0042995,GO:0043005,GO:0043933,GO:0044085,GO:0044087,GO:0044463,GO:0044464,GO:0045595,GO:0045596,GO:0045886,GO:0045926,GO:0048468,GO:0048469,GO:0048519,GO:0048523,GO:0048638,GO:0048640,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051239,GO:0051241,GO:0051259,GO:0051260,GO:0051716,GO:0051960,GO:0051961,GO:0051963,GO:0051964,GO:0060089,GO:0060284,GO:0065003,GO:0065007,GO:0065008,GO:0071695,GO:0071840,GO:0071944,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1904396,GO:1904397,GO:1905809,GO:2000026	-	-	-	-	-	-	-	-	-	-	I-set,Ig_3,fn3
ZZS2_k127_6730615_4	1123288.SOV_6c00170	5.178e-11	70.0	COG5301@1|root,COG5301@2|Bacteria,1UZU2@1239|Firmicutes,4H69E@909932|Negativicutes	909932|Negativicutes	S	Protein of unknown function (DUF2793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793
ZZS2_k127_6730615_5	643562.Daes_2602	8.566e-11	67.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2M84Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
ZZS2_k127_6730615_3	497964.CfE428DRAFT_6673	2.356e-28	116.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS2_k127_6730615_2	1499967.BAYZ01000095_gene4228	3.173e-79	271.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
ZZS2_k127_6730615_1	530564.Psta_2977	2.729e-116	385.0	COG1082@1|root,COG1082@2|Bacteria,2IWZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_6730615_0	497964.CfE428DRAFT_2266	1.862e-199	631.0	COG0477@1|root,COG2814@2|Bacteria,46U08@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
ZZS2_k127_6744359_2	452637.Oter_0714	2.787e-54	195.0	COG1595@1|root,COG1639@1|root,COG1595@2|Bacteria,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HDOD,Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6744359_3	452637.Oter_0712	2.041e-53	209.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
ZZS2_k127_6744359_0	1198114.AciX9_0521	4.148e-92	307.0	COG0745@1|root,COG0745@2|Bacteria,3Y522@57723|Acidobacteria,2JKQX@204432|Acidobacteriia	204432|Acidobacteriia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_6744359_1	1198114.AciX9_0522	5.066e-91	316.0	COG5002@1|root,COG5002@2|Bacteria,3Y5E9@57723|Acidobacteria,2JMCN@204432|Acidobacteriia	204432|Acidobacteriia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_6744359_6	1043205.AFYF01000030_gene487	1.374e-10	76.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
ZZS2_k127_6744359_4	1227487.C474_03200	4.908e-29	136.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_6744359_7	1111730.ATTM01000003_gene310	5.329e-07	64.0	COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NURE@237|Flavobacterium	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,DUF11,Ig_3,P_proprotein,SBBP
ZZS2_k127_6744359_5	868595.Desca_2185	2.026e-13	73.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
ZZS2_k127_6756362_0	1128427.KB904821_gene1705	9.04e-54	201.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Met_10,Methyltransf_21,rRNA_methylase
ZZS2_k127_6756362_2	313606.M23134_08426	2.358e-12	78.0	COG4123@1|root,COG4123@2|Bacteria,4NQKD@976|Bacteroidetes,47RIZ@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
ZZS2_k127_6756362_1	1122197.ATWI01000009_gene1356	1.786e-21	106.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,1T32W@1236|Gammaproteobacteria,468TN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6756362_4	1385520.N802_03070	1.732e-07	64.0	COG0438@1|root,COG0438@2|Bacteria,2GYA2@201174|Actinobacteria,4FG9B@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6756362_3	1096930.L284_18685	2.992e-11	75.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,2U21B@28211|Alphaproteobacteria,2K4WR@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6756579_7	1300345.LF41_48	8.553e-29	131.0	COG0028@1|root,COG1520@1|root,COG3391@1|root,COG3693@1|root,COG0028@2|Bacteria,COG1520@2|Bacteria,COG3391@2|Bacteria,COG3693@2|Bacteria,1QYUP@1224|Proteobacteria	1224|Proteobacteria	EH	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
ZZS2_k127_6756579_11	886293.Sinac_2826	1.153e-15	91.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
ZZS2_k127_6756579_2	314230.DSM3645_14120	1.615e-78	275.0	COG1082@1|root,COG1082@2|Bacteria,2IXNX@203682|Planctomycetes	203682|Planctomycetes	G	COG1082 Sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
ZZS2_k127_6756579_3	65093.PCC7418_1732	3.42e-63	241.0	COG0517@1|root,COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3829@1|root,COG0517@2|Bacteria,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_6756579_9	1280390.CBQR020000092_gene2022	5.855e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_6756579_10	42565.FP66_10745	4.838e-16	88.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,1XPFN@135619|Oceanospirillales	135619|Oceanospirillales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_6756579_12	56107.Cylst_2525	1.196e-15	87.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1HJ6B@1161|Nostocales	1117|Cyanobacteria	K	Two component transcriptional regulator, winged helix family	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_6756579_13	459495.SPLC1_S201840	1.079e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8,Trypsin_2
ZZS2_k127_6756579_4	240016.ABIZ01000001_gene1044	6.406e-57	220.0	2F6YF@1|root,33ZEH@2|Bacteria,46VWD@74201|Verrucomicrobia,2IU9D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6756579_6	1122176.KB903537_gene1651	1.263e-37	154.0	COG2367@1|root,COG2367@2|Bacteria,4NHT5@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
ZZS2_k127_6756579_0	478741.JAFS01000001_gene1298	6.236e-126	414.0	COG0369@1|root,COG0369@2|Bacteria,46UED@74201|Verrucomicrobia,37G1P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	FAD binding domain	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,NAD_binding_1
ZZS2_k127_6756579_1	497964.CfE428DRAFT_2626	1.375e-102	346.0	COG0404@1|root,COG0404@2|Bacteria,46UPA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glycine cleavage T-protein C-terminal barrel domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
ZZS2_k127_6756579_5	1122951.ATUE01000005_gene1787	1.256e-43	164.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,3NNJE@468|Moraxellaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iE2348C_1286.E2348C_3156,iPC815.YPO0906	GCV_H
ZZS2_k127_6756579_8	251221.35211154	8.067e-23	104.0	COG2706@1|root,COG2706@2|Bacteria,1GQSX@1117|Cyanobacteria	1117|Cyanobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TIG,VCBS
ZZS2_k127_6765864_0	929556.Solca_2421	6.623e-227	724.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS2_k127_6765864_4	383372.Rcas_0966	2.157e-59	215.0	COG0637@1|root,COG0637@2|Bacteria,2G7AF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS2_k127_6765864_3	1192034.CAP_8113	4.542e-109	377.0	COG1409@1|root,COG2133@1|root,COG4932@1|root,COG5563@1|root,COG1409@2|Bacteria,COG2133@2|Bacteria,COG4932@2|Bacteria,COG5563@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
ZZS2_k127_6765864_1	221288.JH992901_gene4065	2.218e-198	650.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIX@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
ZZS2_k127_6765864_2	452637.Oter_1440	8.633e-110	363.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_6770732_16	203119.Cthe_0316	8.163e-36	156.0	COG2133@1|root,COG5183@1|root,COG2133@2|Bacteria,COG5183@2|Bacteria,1VRJN@1239|Firmicutes	1239|Firmicutes	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14,RsgI_N
ZZS2_k127_6770732_5	497964.CfE428DRAFT_6298	1.662e-113	381.0	COG1657@1|root,COG1657@2|Bacteria,46TZQ@74201|Verrucomicrobia	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_6770732_25	583355.Caka_2036	1.649e-07	59.0	2F9J5@1|root,341VF@2|Bacteria,46VQB@74201|Verrucomicrobia,3K7XZ@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
ZZS2_k127_6770732_3	1123070.KB899248_gene64	4.123e-125	418.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,2ITI0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS2_k127_6770732_28	930171.Asphe3_37560	0.0007788	49.0	COG3666@1|root,COG3666@2|Bacteria,2IA0I@201174|Actinobacteria	201174|Actinobacteria	L	Protein involved in DNA binding, transposase activity and DNA transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
ZZS2_k127_6770732_6	497964.CfE428DRAFT_5419	4.474e-104	344.0	COG5507@1|root,COG5507@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
ZZS2_k127_6770732_18	497964.CfE428DRAFT_0900	1.502e-28	121.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6770732_9	1396141.BATP01000016_gene2782	1.075e-78	271.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,2IU0K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
ZZS2_k127_6770732_8	394221.Mmar10_0780	8.852e-91	325.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,43XUF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9
ZZS2_k127_6770732_11	1173024.KI912154_gene923	5.086e-55	198.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria,1JIJJ@1189|Stigonemataceae	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_6770732_14	118163.Ple7327_2538	1.537e-37	164.0	COG0745@1|root,COG5001@1|root,COG0745@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3VIJ3@52604|Pleurocapsales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
ZZS2_k127_6770732_4	497964.CfE428DRAFT_3487	1.411e-124	432.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
ZZS2_k127_6770732_7	589865.DaAHT2_2293	1.582e-100	342.0	COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,43B0N@68525|delta/epsilon subdivisions,2X6EQ@28221|Deltaproteobacteria,2MICV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS2_k127_6770732_23	243090.RB107	6.735e-11	67.0	COG1520@1|root,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_6770732_1	1403819.BATR01000090_gene2627	3.161e-163	524.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
ZZS2_k127_6770732_2	1340493.JNIF01000003_gene3012	1.503e-138	485.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria	57723|Acidobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
ZZS2_k127_6770732_24	1120966.AUBU01000005_gene3800	9.477e-11	76.0	28M68@1|root,2ZAJX@2|Bacteria,4NKIW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6770732_21	1254432.SCE1572_09930	5.308e-20	106.0	COG4677@1|root,COG4677@2|Bacteria,1PXT2@1224|Proteobacteria,434TW@68525|delta/epsilon subdivisions,2WZ4T@28221|Deltaproteobacteria,2Z1BV@29|Myxococcales	28221|Deltaproteobacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	NosD
ZZS2_k127_6770732_17	521674.Plim_3783	1.387e-29	125.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6770732_20	886293.Sinac_0045	2.062e-21	107.0	2DNXT@1|root,32ZQ4@2|Bacteria,2J16C@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6770732_13	452637.Oter_1909	1.06e-37	157.0	COG3595@1|root,COG3595@2|Bacteria,46W0J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
ZZS2_k127_6770732_0	497964.CfE428DRAFT_4338	7.485e-205	646.0	COG2960@1|root,COG2960@2|Bacteria,46TXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_6770732_26	313606.M23134_06138	2.254e-06	62.0	COG2931@1|root,COG3203@1|root,COG5306@1|root,COG2931@2|Bacteria,COG3203@2|Bacteria,COG5306@2|Bacteria,4PM6S@976|Bacteroidetes,47Y33@768503|Cytophagia	976|Bacteroidetes	M	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
ZZS2_k127_6770732_15	1396141.BATP01000056_gene3278	3.761e-37	163.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
ZZS2_k127_6770732_19	526224.Bmur_2691	6.686e-28	132.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
ZZS2_k127_6770732_10	1137281.D778_02596	5.522e-78	269.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
ZZS2_k127_6776857_0	243090.RB11088	2.996e-182	589.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_6776857_1	382464.ABSI01000011_gene2813	1.589e-99	337.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
ZZS2_k127_6776857_2	452637.Oter_2329	6.639e-73	253.0	COG3279@1|root,COG3279@2|Bacteria,46VCD@74201|Verrucomicrobia,3K9VV@414999|Opitutae	414999|Opitutae	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
ZZS2_k127_6776857_4	1396141.BATP01000020_gene2	0.0003104	53.0	COG2755@1|root,COG3317@1|root,COG4409@1|root,COG5267@1|root,COG2755@2|Bacteria,COG3317@2|Bacteria,COG4409@2|Bacteria,COG5267@2|Bacteria,46XM5@74201|Verrucomicrobia,2IW6D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,SASA
ZZS2_k127_6776857_3	635013.TherJR_1024	3.01e-07	63.0	COG4733@1|root,COG4733@2|Bacteria,1UTKZ@1239|Firmicutes,253GX@186801|Clostridia	186801|Clostridia	C	SMART Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,Pur_ac_phosph_N
ZZS2_k127_6779843_0	794903.OPIT5_26140	0.0	1117.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS2_k127_6779843_2	452637.Oter_1551	8.785e-65	228.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_6779843_3	497964.CfE428DRAFT_5750	1.458e-55	219.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,46VC0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Histidine kinase	moxY	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
ZZS2_k127_6779843_1	28072.Nos7524_2070	4.716e-97	331.0	COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,1HUA6@1161|Nostocales	1117|Cyanobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_6789631_10	1396141.BATP01000042_gene1918	1.329e-34	154.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
ZZS2_k127_6789631_14	215803.DB30_8307	8.744e-10	72.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
ZZS2_k127_6789631_11	497965.Cyan7822_4213	6.397e-22	112.0	COG4409@1|root,COG4409@2|Bacteria,1GG92@1117|Cyanobacteria	1117|Cyanobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6789631_15	1121920.AUAU01000016_gene1360	7.258e-08	66.0	COG3391@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4733@2|Bacteria,3Y98W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
ZZS2_k127_6789631_13	1317118.ATO8_08351	3.814e-13	83.0	COG2931@1|root,COG3506@1|root,COG3507@1|root,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	CBM_6,Calx-beta,DUF1349,GSDH,Laminin_G_3,PKD,ThuA
ZZS2_k127_6789631_0	1396418.BATQ01000137_gene3892	1.753e-200	639.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
ZZS2_k127_6789631_16	1396141.BATP01000027_gene1124	6.82e-05	47.0	COG0412@1|root,COG0412@2|Bacteria,46SNZ@74201|Verrucomicrobia,2IUD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
ZZS2_k127_6789631_6	530564.Psta_3242	2.099e-91	320.0	COG2319@1|root,COG2319@2|Bacteria,2IXQD@203682|Planctomycetes	203682|Planctomycetes	C	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
ZZS2_k127_6789631_9	382464.ABSI01000005_gene1252	2.455e-50	186.0	COG0125@1|root,COG0125@2|Bacteria,46YZ4@74201|Verrucomicrobia,2IUD6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
ZZS2_k127_6789631_18	1267535.KB906767_gene5177	0.0007118	52.0	COG3258@1|root,COG3258@2|Bacteria,3Y4N3@57723|Acidobacteria,2JJD9@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
ZZS2_k127_6789631_5	1396141.BATP01000003_gene4934	1.715e-126	448.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_6789631_8	640511.BC1002_6686	5.192e-72	252.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6789631_17	1089548.KI783301_gene1	0.0003189	45.0	2DG4E@1|root,2ZUFG@2|Bacteria,1W47E@1239|Firmicutes,4I1MM@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6789631_1	497964.CfE428DRAFT_2609	9.497e-167	536.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
ZZS2_k127_6789631_7	240016.ABIZ01000001_gene2650	1.954e-78	289.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
ZZS2_k127_6789631_4	1183438.GKIL_0514	5.829e-127	414.0	COG0113@1|root,COG0113@2|Bacteria,1G0YH@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
ZZS2_k127_6789631_12	1396418.BATQ01000044_gene6448	1.844e-15	83.0	COG1716@1|root,COG1716@2|Bacteria,46WW1@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
ZZS2_k127_6789631_3	1403819.BATR01000184_gene6355	9.649e-144	465.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
ZZS2_k127_6789631_2	497964.CfE428DRAFT_2042	1.672e-146	471.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_6796062_7	1487953.JMKF01000078_gene4088	3.331e-110	369.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_6796062_13	1242864.D187_005984	1.723e-67	243.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WMED@28221|Deltaproteobacteria,2YYEU@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
ZZS2_k127_6796062_6	163908.KB235896_gene3727	3.332e-114	408.0	COG2374@1|root,COG2931@1|root,COG3204@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3204@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
ZZS2_k127_6796062_14	63737.Npun_F0305	4.184e-56	225.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
ZZS2_k127_6796062_15	469383.Cwoe_0090	4.597e-30	128.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
ZZS2_k127_6796062_17	383372.Rcas_4164	3.658e-17	94.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LIM, zinc-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
ZZS2_k127_6796062_11	1396141.BATP01000028_gene2358	1.891e-86	293.0	COG4912@1|root,COG4912@2|Bacteria,46XAR@74201|Verrucomicrobia,2IV7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
ZZS2_k127_6796062_2	471854.Dfer_1979	7.35e-232	732.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS2_k127_6796062_8	1267535.KB906767_gene1681	6.446e-110	372.0	COG0399@1|root,COG0399@2|Bacteria,3Y7K8@57723|Acidobacteria,2JK8Z@204432|Acidobacteriia	57723|Acidobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_6796062_5	1403819.BATR01000007_gene196	7.109e-158	510.0	COG0388@1|root,COG0388@2|Bacteria,46WMD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
ZZS2_k127_6796062_16	479431.Namu_3903	2.507e-23	102.0	COG1476@1|root,COG1476@2|Bacteria,2I5VF@201174|Actinobacteria,4EWJD@85013|Frankiales	201174|Actinobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
ZZS2_k127_6796062_3	861299.J421_4478	2.032e-181	584.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
ZZS2_k127_6796062_0	395961.Cyan7425_3854	1.5e-323	1003.0	COG1834@1|root,COG1915@1|root,COG1834@2|Bacteria,COG1915@2|Bacteria,1G2AU@1117|Cyanobacteria,3KGE8@43988|Cyanothece	1117|Cyanobacteria	E	LOR SDH bifunctional protein conserved domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
ZZS2_k127_6796062_10	313628.LNTAR_22164	6.902e-90	309.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,fn2
ZZS2_k127_6796062_4	344747.PM8797T_28689	8.586e-173	548.0	COG2382@1|root,COG2382@2|Bacteria,2IX41@203682|Planctomycetes	203682|Planctomycetes	P	COG2382 Enterochelin esterase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_6796062_9	1123242.JH636435_gene953	5.427e-102	361.0	COG0784@1|root,COG3290@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,2J501@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
ZZS2_k127_6796062_1	861299.J421_1109	2.357e-299	930.0	COG1132@1|root,COG1132@2|Bacteria,1ZUSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
ZZS2_k127_6796062_12	926566.Terro_2593	1.978e-71	249.0	COG3119@1|root,COG3119@2|Bacteria,3Y6D1@57723|Acidobacteria,2JK8D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS2_k127_6815602_5	497964.CfE428DRAFT_0809	1.019e-46	173.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6815602_3	1396418.BATQ01000045_gene6076	6.023e-153	492.0	COG0372@1|root,COG0372@2|Bacteria,46SBV@74201|Verrucomicrobia,2ITKN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ZZS2_k127_6815602_2	452637.Oter_2161	2.523e-156	499.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
ZZS2_k127_6815602_1	452637.Oter_2162	4.384e-168	533.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS2_k127_6815602_6	1396141.BATP01000003_gene5038	4.429e-21	102.0	29N11@1|root,344HT@2|Bacteria,46WBB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6815602_4	1396141.BATP01000003_gene5037	8.325e-51	198.0	COG4102@1|root,COG4102@2|Bacteria,46UTF@74201|Verrucomicrobia,2IV1G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_6815602_7	240016.ABIZ01000001_gene4976	3.181e-06	59.0	COG5267@1|root,COG5267@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,DUF1800
ZZS2_k127_6815602_0	886293.Sinac_2748	4.872e-188	601.0	28MB6@1|root,2ZAPQ@2|Bacteria,2IWSP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6823444_0	497964.CfE428DRAFT_2423	2.137e-64	229.0	COG3253@1|root,COG3253@2|Bacteria,46SQD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Chlorite dismutase	ywfI	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
ZZS2_k127_6823444_1	425104.Ssed_1748	1.718e-18	96.0	2AJ20@1|root,319K9@2|Bacteria,1QFG0@1224|Proteobacteria,1TCQ9@1236|Gammaproteobacteria,2QDG3@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
ZZS2_k127_682843_5	742726.HMPREF9448_00667	8.542e-21	109.0	2DUXM@1|root,33SVY@2|Bacteria,4PNIV@976|Bacteroidetes,2FNBQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,CarboxypepD_reg
ZZS2_k127_682843_6	1499967.BAYZ01000190_gene3848	1.428e-11	79.0	COG1404@1|root,COG2911@1|root,COG3121@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03110	-	-	-	ASH,Calx-beta,PapD_N
ZZS2_k127_682843_4	86416.Clopa_2029	3.444e-51	192.0	COG0500@1|root,COG2226@2|Bacteria,1V3HT@1239|Firmicutes,24EY6@186801|Clostridia,36H88@31979|Clostridiaceae	186801|Clostridia	Q	SAM-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_682843_3	886293.Sinac_5436	5.459e-182	581.0	COG1057@1|root,COG1057@2|Bacteria,2IYD8@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_682843_1	1144313.PMI10_02937	9.93e-204	649.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,2NV5I@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS2_k127_682843_0	378806.STAUR_5205	3.244e-252	794.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YXXC@29|Myxococcales	28221|Deltaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS2_k127_682843_2	1210884.HG799465_gene11386	1.289e-183	578.0	COG4948@1|root,COG4948@2|Bacteria,2IY85@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.171	ko:K21624	ko00330,map00330	-	R11625	-	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_6828793_13	324602.Caur_0720	3.151e-09	70.0	COG1572@1|root,COG1572@2|Bacteria,2GBJ4@200795|Chloroflexi,377QB@32061|Chloroflexia	32061|Chloroflexia	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
ZZS2_k127_6828793_1	886293.Sinac_3618	5.636e-209	692.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_6828793_6	497964.CfE428DRAFT_4864	3.522e-61	220.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6828793_4	452637.Oter_1656	1.121e-134	433.0	COG2013@1|root,COG2013@2|Bacteria,46SY6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
ZZS2_k127_6828793_12	1210884.HG799462_gene9247	8.71e-10	66.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	AbfB,Glyco_hydro_43,Sigma70_r4_2
ZZS2_k127_6828793_2	382464.ABSI01000012_gene1990	2.788e-187	595.0	COG2755@1|root,COG2755@2|Bacteria,46V6J@74201|Verrucomicrobia,2IVPY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_6828793_10	324602.Caur_0299	1.523e-32	143.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
ZZS2_k127_6828793_14	269798.CHU_1238	8.566e-06	61.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Dockerin_1,Malectin
ZZS2_k127_6828793_8	1121897.AUGO01000002_gene2177	1.593e-39	173.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia,2NYF6@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_6828793_11	326297.Sama_0391	2.099e-21	113.0	2AKRR@1|root,31BIK@2|Bacteria,1Q7DG@1224|Proteobacteria,1SV5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6828793_0	497964.CfE428DRAFT_0438	1.588e-287	964.0	COG1520@1|root,COG1572@1|root,COG3227@1|root,COG3391@1|root,COG4782@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG3391@2|Bacteria,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	DUF900,FTP,Peptidase_M36
ZZS2_k127_6828793_7	1210884.HG799465_gene11380	3.268e-57	227.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_6828793_5	1116472.MGMO_94c00210	6.084e-89	302.0	COG1028@1|root,COG1028@2|Bacteria,1QWF5@1224|Proteobacteria,1T5MF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_6828793_3	497964.CfE428DRAFT_2545	2.531e-138	447.0	COG0673@1|root,COG0673@2|Bacteria,46VQC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_6828793_9	452637.Oter_1847	2.112e-36	160.0	COG0784@1|root,COG2984@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_6852782_5	1403819.BATR01000191_gene6474	2.856e-115	381.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_6852782_2	497964.CfE428DRAFT_5468	1.144e-201	648.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS2_k127_6852782_6	1210884.HG799473_gene15022	8.997e-91	306.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_6852782_11	1162668.LFE_0740	1.56e-15	81.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS2_k127_6852782_1	497964.CfE428DRAFT_6606	6.622e-235	735.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	PMT_2,Sulfatase,Wzy_C
ZZS2_k127_6852782_7	240016.ABIZ01000001_gene732	2.599e-78	269.0	COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
ZZS2_k127_6852782_0	935557.ATYB01000008_gene5010	9.316e-294	926.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4B8TC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
ZZS2_k127_6852782_8	661478.OP10G_4659	1.06e-46	180.0	2E7BM@1|root,331UY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_6852782_4	1121324.CLIT_2c02270	1.013e-160	519.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_6852782_3	1121324.CLIT_2c02260	1.254e-201	636.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_6852782_9	748247.AZKH_4443	2.167e-39	150.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,2VUQE@28216|Betaproteobacteria,2KYZ3@206389|Rhodocyclales	206389|Rhodocyclales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
ZZS2_k127_6852782_10	583355.Caka_0006	4.291e-33	132.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,3K7VN@414999|Opitutae	414999|Opitutae	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
ZZS2_k127_6858048_3	1123242.JH636435_gene2487	2.412e-84	306.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_6858048_5	497964.CfE428DRAFT_0545	1.5e-55	204.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6858048_9	373994.Riv7116_2884	4.456e-38	146.0	COG3813@1|root,COG3813@2|Bacteria,1GFJM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
ZZS2_k127_6858048_13	640512.BC1003_3625	1.07e-05	55.0	2AJFM@1|root,31A1Y@2|Bacteria,1PW5Q@1224|Proteobacteria,2WBR0@28216|Betaproteobacteria,1K6HN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
ZZS2_k127_6858048_6	545694.TREPR_0418	6.48e-49	199.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
ZZS2_k127_6858048_10	1210884.HG799468_gene13815	4.105e-34	138.0	COG1959@1|root,COG1959@2|Bacteria,2J1K3@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ZZS2_k127_6858048_1	497964.CfE428DRAFT_6182	7.722e-208	654.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	TIGRFAM lysine 2,3-aminomutase YodO family protein	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
ZZS2_k127_6858048_4	1396141.BATP01000039_gene1358	4.485e-57	203.0	COG3558@1|root,COG3558@2|Bacteria,46VBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
ZZS2_k127_6858048_11	591167.Sfla_0348	2.269e-19	95.0	COG0412@1|root,COG0596@1|root,COG0412@2|Bacteria,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DLH
ZZS2_k127_6858048_7	1396141.BATP01000016_gene2810	5.58e-44	186.0	COG1404@1|root,COG1520@1|root,COG4447@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,He_PIG,Peptidase_S8,SLH
ZZS2_k127_6858048_0	1123242.JH636435_gene874	6.985e-235	753.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6858048_2	497964.CfE428DRAFT_5429	8.93e-141	465.0	COG1520@1|root,COG1520@2|Bacteria,46TI7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_6858048_12	1121033.AUCF01000010_gene4563	2.71e-06	57.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2JRTJ@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,Surface_Ag_2
ZZS2_k127_6858048_8	396588.Tgr7_2086	1.379e-43	171.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
ZZS2_k127_6869910_2	497964.CfE428DRAFT_4603	3.087e-24	109.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
ZZS2_k127_6869910_1	518766.Rmar_1172	1.386e-41	165.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,4PEVF@976|Bacteroidetes,1FJP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
ZZS2_k127_6869910_0	1396141.BATP01000007_gene5732	1.104e-144	465.0	COG5564@1|root,COG5564@2|Bacteria,46TKF@74201|Verrucomicrobia,2IVH6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
ZZS2_k127_6964837_3	102125.Xen7305DRAFT_00048450	1.59e-37	165.0	COG2133@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,1G2CB@1117|Cyanobacteria,3VM5E@52604|Pleurocapsales	1117|Cyanobacteria	GQ	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,Lectin_C
ZZS2_k127_6964837_5	469383.Cwoe_1660	1.285e-24	123.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA14,SLH,fn3
ZZS2_k127_6964837_8	1210884.HG799470_gene14271	5.264e-11	78.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG4719@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4719@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_6964837_1	316274.Haur_2195	1.156e-120	436.0	COG2304@1|root,COG2304@2|Bacteria,2GA79@200795|Chloroflexi,375RC@32061|Chloroflexia	32061|Chloroflexia	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
ZZS2_k127_6964837_7	497964.CfE428DRAFT_2672	5.144e-11	68.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
ZZS2_k127_6964837_9	313612.L8106_17667	3.55e-05	51.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
ZZS2_k127_6964837_4	497964.CfE428DRAFT_4864	1.321e-28	120.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6964837_6	102129.Lepto7375DRAFT_2567	1.622e-17	98.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14,Trypsin_2
ZZS2_k127_6964837_2	314230.DSM3645_12486	5.75e-97	346.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_6964837_0	497964.CfE428DRAFT_4431	9.43e-208	680.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
ZZS2_k127_6969586_0	530564.Psta_4044	9.658e-75	280.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_6974460_0	1163617.SCD_n02091	1.017e-239	758.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
ZZS2_k127_6974460_3	1042877.GQS_10620	1.04e-13	82.0	arCOG03610@1|root,arCOG03610@2157|Archaea,2Y143@28890|Euryarchaeota,245M4@183968|Thermococci	183968|Thermococci	O	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6974460_2	105559.Nwat_0379	3.743e-14	79.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,1S926@1236|Gammaproteobacteria,1WZ45@135613|Chromatiales	135613|Chromatiales	S	periplasmic or secreted lipoprotein	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
ZZS2_k127_6974460_4	1396141.BATP01000001_gene5308	1.591e-09	65.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_6975477_3	1210045.ALNP01000003_gene4439	3.716e-06	62.0	COG0823@1|root,COG2304@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PD40,VWA
ZZS2_k127_6975477_2	1196323.ALKF01000187_gene5774	1.323e-49	205.0	COG1680@1|root,COG1680@2|Bacteria,1UWSD@1239|Firmicutes,4HZJ8@91061|Bacilli	91061|Bacilli	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6975477_1	867845.KI911784_gene1260	5.793e-50	207.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
ZZS2_k127_6975477_0	382464.ABSI01000009_gene3902	8.237e-59	236.0	COG1686@1|root,COG5555@1|root,COG1686@2|Bacteria,COG5555@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4,6.3.2.10	ko:K01929,ko:K07258	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	FG-GAP,Peptidase_S11
ZZS2_k127_699980_2	1304885.AUEY01000116_gene2848	1.576e-33	147.0	COG3852@1|root,COG3852@2|Bacteria,1RCUD@1224|Proteobacteria,42R9I@68525|delta/epsilon subdivisions,2WN53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS2_k127_699980_0	661478.OP10G_4206	4.652e-40	168.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
ZZS2_k127_699980_4	1304872.JAGC01000009_gene596	3.655e-27	128.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2M98X@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_699980_3	521674.Plim_3639	5.829e-33	144.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
ZZS2_k127_699980_5	1247963.JPHU01000001_gene2140	3.64e-06	58.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,2UAXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	General secretion pathway protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
ZZS2_k127_699980_6	1255043.TVNIR_1921	0.0001991	51.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1WY85@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein H	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
ZZS2_k127_699980_1	861299.J421_6307	1.93e-35	139.0	COG2165@1|root,COG2165@2|Bacteria,1ZTUY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS2_k127_7004655_8	1396418.BATQ01000136_gene3705	1.015e-83	292.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
ZZS2_k127_7004655_17	497964.CfE428DRAFT_0593	2.76e-05	54.0	COG3666@1|root,COG3666@2|Bacteria,46S8M@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
ZZS2_k127_7004655_14	1384056.N787_05865	4.939e-46	179.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1X412@135614|Xanthomonadales	135614|Xanthomonadales	P	Pit accessory protein	VL23_21310	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
ZZS2_k127_7004655_10	1396141.BATP01000003_gene4925	2.137e-57	206.0	COG1392@1|root,COG1392@2|Bacteria,46SSJ@74201|Verrucomicrobia,2IVZ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU_div
ZZS2_k127_7004655_5	452637.Oter_2552	2.028e-109	370.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia,3K7HD@414999|Opitutae	74201|Verrucomicrobia	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
ZZS2_k127_7004655_12	1396141.BATP01000003_gene4925	1.145e-54	199.0	COG1392@1|root,COG1392@2|Bacteria,46SSJ@74201|Verrucomicrobia,2IVZ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU_div
ZZS2_k127_7004655_11	1396141.BATP01000003_gene4925	2.635e-56	203.0	COG1392@1|root,COG1392@2|Bacteria,46SSJ@74201|Verrucomicrobia,2IVZ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU_div
ZZS2_k127_7004655_16	1454004.AW11_02488	9.035e-41	165.0	COG0394@1|root,COG0704@1|root,COG0394@2|Bacteria,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	1.20.4.1,3.1.3.48	ko:K01104,ko:K02039,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	PhoU
ZZS2_k127_7004655_7	517418.Ctha_0917	8.396e-88	299.0	COG0226@1|root,COG0226@2|Bacteria,1FE4N@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
ZZS2_k127_7004655_3	517418.Ctha_0918	3.367e-114	377.0	COG0573@1|root,COG0573@2|Bacteria,1FE1M@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstC	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_7004655_1	517418.Ctha_0919	2.38e-129	421.0	COG0581@1|root,COG0581@2|Bacteria,1FE3G@1090|Chlorobi	1090|Chlorobi	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_7004655_4	517418.Ctha_0920	3.877e-114	372.0	COG1117@1|root,COG1117@2|Bacteria	2|Bacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS2_k127_7004655_2	517418.Ctha_0921	3.538e-115	377.0	COG1117@1|root,COG1117@2|Bacteria,1FEHB@1090|Chlorobi	1090|Chlorobi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS2_k127_7004655_13	497964.CfE428DRAFT_4165	1.521e-54	199.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
ZZS2_k127_7004655_18	1123508.JH636442_gene4021	5.518e-05	49.0	2DXZ8@1|root,3479Q@2|Bacteria,2J3XJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7004655_15	1219084.AP014508_gene467	2.672e-44	171.0	COG2071@1|root,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
ZZS2_k127_7004655_6	1125863.JAFN01000001_gene2253	1.755e-108	368.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_7004655_9	497964.CfE428DRAFT_4164	4.163e-59	217.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ZZS2_k127_7004655_0	497964.CfE428DRAFT_1386	0.0	1252.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
ZZS2_k127_7024861_12	439235.Dalk_1959	5.563e-37	147.0	2E0G4@1|root,32W27@2|Bacteria,1N463@1224|Proteobacteria,42VTW@68525|delta/epsilon subdivisions,2WSDZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
ZZS2_k127_7024861_0	452637.Oter_2327	1.633e-280	881.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7024861_6	382464.ABSI01000010_gene3649	2.247e-77	265.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia,2IVQR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_7024861_4	595460.RRSWK_04695	6.22e-101	353.0	COG5002@1|root,COG5002@2|Bacteria,2IY3P@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_7024861_5	886293.Sinac_5296	5.173e-83	300.0	COG0793@1|root,COG0793@2|Bacteria,2IX9Q@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ZZS2_k127_7024861_11	1304880.JAGB01000002_gene1827	8.016e-39	148.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia	186801|Clostridia	C	assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
ZZS2_k127_7024861_3	871968.DESME_10735	4.46e-102	346.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_7024861_2	452637.Oter_4588	3.821e-116	383.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
ZZS2_k127_7024861_7	497964.CfE428DRAFT_0566	1.576e-65	228.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
ZZS2_k127_7024861_10	278957.ABEA03000050_gene160	5.876e-41	157.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
ZZS2_k127_7024861_1	240016.ABIZ01000001_gene3008	6.235e-133	439.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7024861_9	251221.35213566	6.466e-43	175.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7024861_8	1286631.X805_30960	1.026e-49	196.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
ZZS2_k127_7026535_1	661478.OP10G_0362	8.673e-76	283.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,DUF4185
ZZS2_k127_7026535_2	1144275.COCOR_01832	2.93e-48	198.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
ZZS2_k127_7026535_4	573061.Clocel_1966	1.065e-32	147.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_7026535_6	481448.Minf_0431	1.733e-14	76.0	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia,37GVN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS2_k127_7026535_3	1403819.BATR01000181_gene6219	1.256e-36	150.0	COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,2IVST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_7026535_7	1123242.JH636435_gene1865	0.0001181	52.0	292E7@1|root,2ZPYF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7026535_5	251221.35211911	1.986e-24	121.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,TIG,VCBS
ZZS2_k127_7026535_0	56110.Oscil6304_2815	6.338e-77	293.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
ZZS2_k127_7031895_19	1242864.D187_004162	3.275e-10	70.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,42YPE@68525|delta/epsilon subdivisions,2WU63@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_7031895_14	204669.Acid345_2868	2.271e-35	154.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria,2JI17@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7031895_0	357808.RoseRS_2679	0.0	1019.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G5QP@200795|Chloroflexi,3770F@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
ZZS2_k127_7031895_3	247490.KSU1_D0782	1.038e-154	502.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7031895_6	247490.KSU1_D0783	2.809e-95	321.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
ZZS2_k127_7031895_12	247490.KSU1_D0784	1.832e-50	191.0	COG1121@1|root,COG1121@2|Bacteria,2IYC3@203682|Planctomycetes	203682|Planctomycetes	P	COG1121 ABC-type Mn Zn transport systems ATPase component	-	-	-	ko:K11607,ko:K11710	ko02010,map02010	M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
ZZS2_k127_7031895_9	247490.KSU1_D0785	1.594e-69	248.0	COG1108@1|root,COG1108@2|Bacteria	2|Bacteria	P	ABC-type Mn2 Zn2 transport systems permease components	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
ZZS2_k127_7031895_7	497964.CfE428DRAFT_4495	1.449e-89	305.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
ZZS2_k127_7031895_18	497964.CfE428DRAFT_4494	1.335e-16	81.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
ZZS2_k127_7031895_13	497964.CfE428DRAFT_4493	2.87e-40	157.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
ZZS2_k127_7031895_17	1396141.BATP01000030_gene3799	1.33e-26	113.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
ZZS2_k127_7031895_1	497964.CfE428DRAFT_4491	5.257e-248	774.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
ZZS2_k127_7031895_5	497964.CfE428DRAFT_4490	2.019e-96	324.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
ZZS2_k127_7031895_2	497964.CfE428DRAFT_4489	2.405e-233	731.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS2_k127_7031895_15	481448.Minf_2424	1.286e-31	128.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,37GUN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
ZZS2_k127_7031895_8	497964.CfE428DRAFT_2060	1.499e-80	280.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS2_k127_7031895_11	240016.ABIZ01000001_gene3616	4.71e-57	206.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7031895_4	344747.PM8797T_20983	1.72e-141	461.0	COG1520@1|root,COG1520@2|Bacteria,2J213@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7031895_16	666681.M301_0767	1.305e-28	125.0	2EFC8@1|root,33955@2|Bacteria,1NCIW@1224|Proteobacteria,2W84Q@28216|Betaproteobacteria,2KNXZ@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7031895_10	794903.OPIT5_18175	2.145e-59	215.0	COG1785@1|root,COG1785@2|Bacteria,46X6W@74201|Verrucomicrobia,3K88S@414999|Opitutae	414999|Opitutae	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
ZZS2_k127_7039245_0	485913.Krac_4586	1.46e-118	426.0	COG2133@1|root,COG2355@1|root,COG2133@2|Bacteria,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_7039245_5	865937.Gilli_0558	3.865e-37	164.0	COG1520@1|root,COG2304@1|root,COG3391@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG3391@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2P5SV@244698|Gillisia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
ZZS2_k127_7039245_3	118168.MC7420_6744	1.537e-56	223.0	COG0642@1|root,COG2205@2|Bacteria,1FZVR@1117|Cyanobacteria,1H8C7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_7039245_1	1396141.BATP01000025_gene980	2.371e-66	234.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_7039245_4	1210884.HG799469_gene14163	5.822e-47	176.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_7039245_2	595460.RRSWK_03115	1.556e-60	224.0	COG1520@1|root,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_7058384_3	324602.Caur_0300	2.436e-12	75.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7058384_5	452637.Oter_2718	3.739e-08	59.0	COG1758@1|root,COG1758@2|Bacteria,46T94@74201|Verrucomicrobia,3K8FM@414999|Opitutae	414999|Opitutae	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
ZZS2_k127_7058384_1	68199.JNZO01000032_gene4184	2.259e-40	154.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
ZZS2_k127_7058384_2	278957.ABEA03000012_gene2672	9.802e-20	92.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,3K89C@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
ZZS2_k127_7058384_0	1303518.CCALI_00783	7.484e-108	366.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7058384_4	880070.Cycma_4604	5.832e-11	71.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS2_k127_7108053_2	344747.PM8797T_06150	3.429e-111	374.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7108053_8	1536770.R50345_02920	4.45e-26	117.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,26TZY@186822|Paenibacillaceae	91061|Bacilli	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
ZZS2_k127_7108053_6	1210884.HG799472_gene14772	4.964e-58	218.0	COG1520@1|root,COG1520@2|Bacteria,2J2AJ@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7108053_3	497964.CfE428DRAFT_2550	1.762e-83	283.0	COG1208@1|root,COG1208@2|Bacteria,46UUZ@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
ZZS2_k127_7108053_1	452637.Oter_3977	1.899e-149	478.0	COG2605@1|root,COG2605@2|Bacteria,46UPC@74201|Verrucomicrobia	74201|Verrucomicrobia	H	GHMP kinase domain protein	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ZZS2_k127_7108053_7	522306.CAP2UW1_1842	3.55e-52	192.0	COG0500@1|root,COG2226@2|Bacteria,1Q73B@1224|Proteobacteria,2W6KU@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_7108053_0	452637.Oter_3018	1.145e-211	670.0	COG0166@1|root,COG0166@2|Bacteria,46SUH@74201|Verrucomicrobia,3K7K9@414999|Opitutae	414999|Opitutae	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
ZZS2_k127_7108053_9	530564.Psta_4448	4.305e-23	101.0	2CKQA@1|root,30U0C@2|Bacteria,2J1CW@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7108053_4	880526.KE386488_gene1497	1.34e-65	235.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,2FN71@200643|Bacteroidia,22UH9@171550|Rikenellaceae	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
ZZS2_k127_7108053_5	478741.JAFS01000001_gene1574	3.08e-63	230.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,37G0D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
ZZS2_k127_7108053_10	497964.CfE428DRAFT_3795	4.137e-13	82.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7108713_2	497964.CfE428DRAFT_6180	2.412e-128	426.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
ZZS2_k127_7108713_7	1507.HMPREF0262_02693	1.094e-17	87.0	2ED8C@1|root,3374X@2|Bacteria,1W0C5@1239|Firmicutes,24S5N@186801|Clostridia,36SWT@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Smr
ZZS2_k127_7108713_8	1122175.ATXU01000011_gene1606	9.244e-05	52.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4FKR6@85023|Microbacteriaceae	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
ZZS2_k127_7108713_4	497964.CfE428DRAFT_0685	2.135e-46	190.0	297A6@1|root,2ZUHR@2|Bacteria	497964.CfE428DRAFT_0685|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7108713_3	497964.CfE428DRAFT_0687	9.403e-110	363.0	COG1131@1|root,COG1131@2|Bacteria,46U5D@74201|Verrucomicrobia	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_7108713_5	1300345.LF41_2669	1.162e-22	102.0	COG1725@1|root,COG1725@2|Bacteria,1N163@1224|Proteobacteria,1RW9X@1236|Gammaproteobacteria,1X7CS@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
ZZS2_k127_7108713_6	1396141.BATP01000035_gene4105	2.182e-22	98.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia,2IUN6@203494|Verrucomicrobiae	2|Bacteria	K	ECF sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
ZZS2_k127_7108713_1	509635.N824_21660	4.684e-152	492.0	COG0477@1|root,COG2814@2|Bacteria,4NE1N@976|Bacteroidetes,1IQ52@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	fsr	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
ZZS2_k127_7108713_0	1265502.KB905966_gene1222	1.366e-166	554.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,4A9JE@80864|Comamonadaceae	28216|Betaproteobacteria	EK	PFAM aminotransferase, class I and II	lysN	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
ZZS2_k127_7122685_1	870187.Thini_3662	7.311e-32	145.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_7122685_0	234267.Acid_5562	5.722e-41	170.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7128287_3	661478.OP10G_4575	1.125e-204	648.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
ZZS2_k127_7128287_0	1469607.KK073768_gene2205	0.0	1431.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
ZZS2_k127_7128287_31	452637.Oter_2422	0.0002075	48.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_7128287_30	498761.HM1_1703	9.415e-07	57.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia	186801|Clostridia	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS2_k127_7128287_16	219305.MCAG_05046	8.36e-98	346.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG5297@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG5297@2|Bacteria,2GJFY@201174|Actinobacteria,4D9XB@85008|Micromonosporales	201174|Actinobacteria	G	Cellulose Binding Domain Type IV	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,F5_F8_type_C,GSDH,PKD,ThuA
ZZS2_k127_7128287_2	240016.ABIZ01000001_gene585	1.659e-220	698.0	COG0079@1|root,COG0079@2|Bacteria,46X8Y@74201|Verrucomicrobia,2IV1Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Aminotran_1_2
ZZS2_k127_7128287_17	886293.Sinac_3352	2.171e-92	317.0	COG0524@1|root,COG0524@2|Bacteria,2IZDG@203682|Planctomycetes	203682|Planctomycetes	G	COG0524 Sugar kinases, ribokinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ZZS2_k127_7128287_22	344747.PM8797T_23049	8.802e-60	219.0	2CBIH@1|root,33WXG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7128287_8	1183438.GKIL_3693	5.738e-121	406.0	COG3569@1|root,COG3569@2|Bacteria,1G2R6@1117|Cyanobacteria	1117|Cyanobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
ZZS2_k127_7128287_28	1121943.KB899989_gene3435	4.805e-08	58.0	COG3963@1|root,COG3963@2|Bacteria,1RATY@1224|Proteobacteria,1S1YM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	methyltransferase	ksgA1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
ZZS2_k127_7128287_7	497964.CfE428DRAFT_2215	1.565e-124	417.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS2_k127_7128287_1	344747.PM8797T_19480	1.038e-295	944.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrom_C,GSDH,HEAT_2
ZZS2_k127_7128287_21	794903.OPIT5_26370	5.533e-61	222.0	COG1714@1|root,COG1714@2|Bacteria,46Z5U@74201|Verrucomicrobia,3K8J3@414999|Opitutae	414999|Opitutae	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
ZZS2_k127_7128287_29	391008.Smal_3698	8.647e-07	57.0	2E37T@1|root,32Y7G@2|Bacteria,1NKGS@1224|Proteobacteria,1T65R@1236|Gammaproteobacteria,1X8HF@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
ZZS2_k127_7128287_25	398767.Glov_3582	6.081e-31	129.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7128287_27	497964.CfE428DRAFT_2654	1.207e-12	75.0	2EG13@1|root,339T4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7128287_26	439235.Dalk_0970	3.422e-23	102.0	2EE20@1|root,337WQ@2|Bacteria,1P7Y2@1224|Proteobacteria,433SZ@68525|delta/epsilon subdivisions,2WXV7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7128287_13	497964.CfE428DRAFT_2656	7.988e-109	371.0	2EQIM@1|root,2ZBQ8@2|Bacteria,46TFZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
ZZS2_k127_7128287_19	497964.CfE428DRAFT_2657	1.872e-65	241.0	COG5414@1|root,COG5414@2|Bacteria,46VD3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7128287_6	497964.CfE428DRAFT_2658	3.672e-142	457.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_7128287_4	497964.CfE428DRAFT_2659	4.317e-146	476.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_7128287_9	439235.Dalk_0975	3.149e-118	389.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2MNT3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
ZZS2_k127_7128287_18	497964.CfE428DRAFT_2661	1.761e-81	278.0	COG1714@1|root,COG1714@2|Bacteria,46UT5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
ZZS2_k127_7128287_20	794903.OPIT5_23685	8.509e-64	234.0	COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS2_k127_7128287_15	497964.CfE428DRAFT_5013	4.085e-100	335.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
ZZS2_k127_7128287_24	1123242.JH636435_gene2796	4.286e-39	155.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_7128287_5	1123242.JH636435_gene2797	2.019e-144	474.0	COG2010@1|root,COG2010@2|Bacteria,2J547@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7128287_14	8081.XP_008408411.1	1.045e-100	346.0	KOG3698@1|root,KOG3698@2759|Eukaryota,38D91@33154|Opisthokonta,3BG5D@33208|Metazoa,3D3T0@33213|Bilateria,48D3V@7711|Chordata,49AFP@7742|Vertebrata,49XKJ@7898|Actinopterygii	33208|Metazoa	O	Meningioma expressed antigen 5 (hyaluronidase)	-	-	2.3.1.48,3.2.1.169	ko:K15719	ko04931,map04931	-	R09672,R09673	RC00059,RC00397,RC00451,RC00746	ko00000,ko00001,ko01000	-	GH84	-	NAGidase
ZZS2_k127_7128287_23	649638.Trad_0164	1.883e-48	186.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS2_k127_7128287_12	1123277.KB893244_gene5166	4.578e-111	376.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_7128287_10	1321778.HMPREF1982_00675	1.722e-114	384.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,26AG8@186813|unclassified Clostridiales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
ZZS2_k127_7128287_11	1123073.KB899241_gene3145	2.477e-111	368.0	COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,1RRUQ@1236|Gammaproteobacteria,1XCF4@135614|Xanthomonadales	135614|Xanthomonadales	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
ZZS2_k127_7129912_1	1267535.KB906767_gene1958	8.986e-127	434.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
ZZS2_k127_7129912_4	1267535.KB906767_gene1959	1.325e-53	196.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_7129912_5	1121396.KB893077_gene747	9.4e-10	62.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
ZZS2_k127_7129912_0	760192.Halhy_5620	8.229e-159	512.0	COG0477@1|root,COG2814@2|Bacteria,4PNZI@976|Bacteroidetes	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_7129912_2	1123242.JH636434_gene4801	3.873e-114	373.0	COG1028@1|root,COG1028@2|Bacteria	1123242.JH636434_gene4801|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7129912_3	324602.Caur_1732	7.571e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_714037_4	497964.CfE428DRAFT_3738	2.315e-124	402.0	COG1402@1|root,COG1402@2|Bacteria,46WYK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
ZZS2_k127_714037_3	240016.ABIZ01000001_gene225	6.903e-129	426.0	COG2271@1|root,COG2807@1|root,COG2271@2|Bacteria,COG2807@2|Bacteria,46TJN@74201|Verrucomicrobia,2IVYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_714037_5	1267535.KB906767_gene4929	2.1e-120	400.0	28KEJ@1|root,2ZA0T@2|Bacteria,3Y6AA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_714037_2	452637.Oter_2109	1.935e-168	533.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,3K7UW@414999|Opitutae	414999|Opitutae	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
ZZS2_k127_714037_1	344747.PM8797T_29708	2.519e-170	543.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
ZZS2_k127_714037_0	794903.OPIT5_17790	9.311e-206	649.0	COG0477@1|root,COG2814@2|Bacteria,46Z9E@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_7183565_4	1121011.AUCB01000008_gene1241	9.621e-05	57.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
ZZS2_k127_7183565_0	1121481.AUAS01000006_gene877	7.478e-56	226.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
ZZS2_k127_7183565_1	1121377.KB906417_gene3855	4.962e-17	98.0	2FA15@1|root,342A8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7183565_2	938709.AUSH02000045_gene357	6.279e-14	87.0	COG1361@1|root,COG1506@1|root,COG2304@1|root,COG2374@1|root,COG3209@1|root,COG3391@1|root,COG4886@1|root,COG5184@1|root,COG1361@2|Bacteria,COG1506@2|Bacteria,COG2304@2|Bacteria,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	rapB1	-	1.14.17.3,3.2.1.8	ko:K00504,ko:K01181,ko:K06889,ko:K07004,ko:K12548	-	-	-	-	ko00000,ko01000	-	-	-	CHU_C,DUF11
ZZS2_k127_7238233_10	1121481.AUAS01000004_gene1379	1.399e-39	152.0	COG0800@1|root,COG0800@2|Bacteria,4NHVV@976|Bacteroidetes,47MP6@768503|Cytophagia	976|Bacteroidetes	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
ZZS2_k127_7238233_9	926549.KI421517_gene3140	6.427e-53	202.0	COG3734@1|root,COG3734@2|Bacteria,4NIGZ@976|Bacteroidetes,47NSE@768503|Cytophagia	976|Bacteroidetes	G	2-keto-3-deoxy-galactonokinase	-	-	2.7.1.58	ko:K00883	ko00052,ko01100,map00052,map01100	M00552	R03387	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DGOK
ZZS2_k127_7238233_0	497964.CfE428DRAFT_4093	0.0	1548.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
ZZS2_k127_7238233_5	425104.Ssed_1747	1.704e-113	391.0	COG0366@1|root,COG1409@1|root,COG0366@2|Bacteria,COG1409@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
ZZS2_k127_7238233_4	314230.DSM3645_17570	2.339e-124	416.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,2IX32@203682|Planctomycetes	203682|Planctomycetes	Q	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25,Methyltransf_31
ZZS2_k127_7238233_11	1206733.BAGC01000009_gene5035	8.15e-31	132.0	2APEP@1|root,31EHC@2|Bacteria,2H5GN@201174|Actinobacteria,4G1XR@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7238233_1	1242864.D187_000183	1.004e-267	876.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,43AAU@68525|delta/epsilon subdivisions,2X9T6@28221|Deltaproteobacteria,2YU9S@29|Myxococcales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
ZZS2_k127_7238233_7	1242864.D187_005461	1.618e-71	258.0	COG0457@1|root,COG0457@2|Bacteria,1R8TH@1224|Proteobacteria,438CY@68525|delta/epsilon subdivisions,2X3N4@28221|Deltaproteobacteria,2YWKT@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7238233_2	1116472.MGMO_120c00330	4.008e-178	582.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XEX4@135618|Methylococcales	135618|Methylococcales	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
ZZS2_k127_7238233_17	1034769.KB910518_gene1577	7.611e-06	55.0	COG3064@1|root,COG3064@2|Bacteria,1UNMA@1239|Firmicutes,4IUI0@91061|Bacilli,270MC@186822|Paenibacillaceae	91061|Bacilli	M	Type VI secretion system effector, Hcp	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7238233_15	243160.BMAA0734	4.73e-20	94.0	COG1196@1|root,COG1196@2|Bacteria,1NJUM@1224|Proteobacteria,2VX9F@28216|Betaproteobacteria,1KII2@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Domain of unknown function (DUF4150)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150
ZZS2_k127_7238233_6	1254432.SCE1572_19080	6.413e-104	366.0	COG1357@1|root,COG5351@1|root,COG1357@2|Bacteria,COG5351@2|Bacteria,1N7U9@1224|Proteobacteria,43A2C@68525|delta/epsilon subdivisions,2X2II@28221|Deltaproteobacteria,2YYVI@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169,Pentapeptide
ZZS2_k127_7238233_8	1254432.SCE1572_19085	1.251e-56	221.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,42UJ1@68525|delta/epsilon subdivisions,2WR2I@28221|Deltaproteobacteria,2YZRT@29|Myxococcales	28221|Deltaproteobacteria	S	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
ZZS2_k127_7238233_3	1288494.EBAPG3_5740	1.024e-175	575.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	rhs element vgr protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
ZZS2_k127_7238233_16	1123242.JH636434_gene3936	2.02e-07	61.0	COG2825@1|root,COG2825@2|Bacteria,2J441@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
ZZS2_k127_7238233_18	1123320.KB889708_gene8372	0.0002699	44.0	COG3420@1|root,COG3420@2|Bacteria,2GN61@201174|Actinobacteria	201174|Actinobacteria	P	Chondroitinase B	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Chondroitinas_B
ZZS2_k127_7254842_17	497964.CfE428DRAFT_2511	5.355e-67	234.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
ZZS2_k127_7254842_3	1123248.KB893385_gene4912	3.828e-164	520.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7254842_12	1123248.KB893385_gene4913	1.366e-93	319.0	COG2120@1|root,COG2120@2|Bacteria,4P03X@976|Bacteroidetes	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS2_k127_7254842_5	641524.ADICYQ_2925	3.764e-143	462.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7254842_8	794903.OPIT5_13610	1.12e-119	407.0	COG2831@1|root,COG2831@2|Bacteria	2|Bacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
ZZS2_k127_7254842_7	1380394.JADL01000001_gene2956	1.318e-126	460.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria,2JRTA@204441|Rhodospirillales	204441|Rhodospirillales	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
ZZS2_k127_7254842_0	338966.Ppro_2148	4.175e-232	759.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria,43T50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
ZZS2_k127_7254842_1	269799.Gmet_1893	7.187e-232	763.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria,43T98@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
ZZS2_k127_7254842_6	290315.Clim_1358	9.742e-143	479.0	COG0507@1|root,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2,Viral_helicase1
ZZS2_k127_7254842_19	240016.ABIZ01000001_gene5378	2.144e-47	175.0	COG0071@1|root,COG0071@2|Bacteria,46T3G@74201|Verrucomicrobia,2IVVF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
ZZS2_k127_7254842_21	1210884.HG799463_gene9897	8.274e-25	115.0	COG0500@1|root,COG2226@2|Bacteria,2J51A@203682|Planctomycetes	203682|Planctomycetes	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ZZS2_k127_7254842_2	1396141.BATP01000013_gene2687	1.511e-177	574.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,2ITYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AICARFT/IMPCHase bienzyme	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
ZZS2_k127_7254842_25	357808.RoseRS_1520	4.41e-05	51.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
ZZS2_k127_7254842_23	1242864.D187_010007	1.661e-09	67.0	COG1596@1|root,COG1596@2|Bacteria,1N6I6@1224|Proteobacteria,42UGK@68525|delta/epsilon subdivisions,2WQTF@28221|Deltaproteobacteria,2YVVS@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS2_k127_7254842_24	1121015.N789_03460	1.296e-06	59.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1X7BN@135614|Xanthomonadales	135614|Xanthomonadales	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
ZZS2_k127_7254842_9	497964.CfE428DRAFT_6114	1.385e-114	396.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
ZZS2_k127_7254842_22	1396418.BATQ01000163_gene1951	7.196e-10	71.0	2BUZ4@1|root,32QBJ@2|Bacteria,46WND@74201|Verrucomicrobia,2IUIR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
ZZS2_k127_7254842_20	452637.Oter_2104	1.61e-39	167.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7254842_4	481448.Minf_2098	4e-144	470.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,37GCZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_7254842_11	478741.JAFS01000002_gene392	2.165e-95	327.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,37FXN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PAS domain	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
ZZS2_k127_7254842_14	794903.OPIT5_18260	6.372e-86	295.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,3K7J8@414999|Opitutae	414999|Opitutae	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ZZS2_k127_7254842_13	278957.ABEA03000104_gene310	6.495e-92	307.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
ZZS2_k127_7254842_15	497964.CfE428DRAFT_3158	1.787e-84	291.0	COG0240@1|root,COG0240@2|Bacteria,46SQJ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
ZZS2_k127_7254842_18	478741.JAFS01000002_gene421	1.516e-48	181.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,37GTF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
ZZS2_k127_7254842_10	497964.CfE428DRAFT_0881	4.717e-109	363.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_7254842_16	1156937.MFUM_680012	9.399e-80	279.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
ZZS2_k127_7262107_0	382464.ABSI01000011_gene3025	1.54e-123	406.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS2_k127_7262107_1	497964.CfE428DRAFT_0568	2.145e-61	218.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
ZZS2_k127_7262107_2	555079.Toce_1073	3.01e-17	87.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,42H26@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
ZZS2_k127_7279294_2	1210884.HG799465_gene11380	6.859e-32	134.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_7279294_1	349741.Amuc_1517	5.059e-52	191.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_7279294_3	326427.Cagg_3284	2.835e-18	100.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
ZZS2_k127_7279294_4	251221.35210810	4.111e-16	93.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7279294_0	452637.Oter_0358	1.502e-101	366.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46YZC@74201|Verrucomicrobia,3K9WB@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_7293572_0	886293.Sinac_0401	7.933e-190	612.0	COG5426@1|root,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
ZZS2_k127_7293572_3	1173263.Syn7502_03499	1.52e-11	75.0	COG1413@1|root,COG1413@2|Bacteria,1G2ZR@1117|Cyanobacteria	1117|Cyanobacteria	CT	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Vitellogenin_N
ZZS2_k127_7293572_2	498848.TaqDRAFT_4878	4.505e-80	293.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7293572_1	316067.Geob_2986	7.006e-94	346.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
ZZS2_k127_7343_18	1237149.C900_00684	4.02e-07	62.0	COG3209@1|root,COG4733@1|root,COG4886@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Big_2,DUF4988,He_PIG
ZZS2_k127_7343_0	886293.Sinac_1376	0.0	1108.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXJQ@203682|Planctomycetes	2|Bacteria	C	polysaccharide deacetylase	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Ceramidase_alk,Copper-bind,Cytochrom_C,DUF1080,HEAT_2,Lipase_GDSL_2,ThuA,VCBS
ZZS2_k127_7343_2	497964.CfE428DRAFT_2561	3.583e-215	679.0	28JEC@1|root,2Z98J@2|Bacteria,46U3F@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7343_12	635013.TherJR_1429	6.912e-44	164.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,24HUX@186801|Clostridia,261V6@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
ZZS2_k127_7343_3	497964.CfE428DRAFT_1457	1.873e-209	665.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	General secretory system II protein E domain protein	pulE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_7343_7	313628.LNTAR_05914	5.023e-139	451.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_7343_1	497964.CfE428DRAFT_1455	1.388e-218	691.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_7343_6	497964.CfE428DRAFT_1451	4.116e-143	466.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_7343_17	1396141.BATP01000003_gene5165	7.383e-08	58.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
ZZS2_k127_7343_14	452637.Oter_0872	6.384e-17	83.0	COG1918@1|root,COG1918@2|Bacteria,46WNZ@74201|Verrucomicrobia	74201|Verrucomicrobia	P	FeoA domain	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
ZZS2_k127_7343_4	452637.Oter_0871	3.122e-195	633.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
ZZS2_k127_7343_10	861299.J421_2387	1.493e-96	327.0	COG1680@1|root,COG1680@2|Bacteria,1ZV34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_7343_9	497964.CfE428DRAFT_4880	2.679e-108	370.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,46T28@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_31
ZZS2_k127_7343_16	1123253.AUBD01000002_gene1181	6.092e-08	68.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1X52C@135614|Xanthomonadales	135614|Xanthomonadales	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
ZZS2_k127_7343_5	452637.Oter_2857	4.722e-161	513.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,3K7B2@414999|Opitutae	414999|Opitutae	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
ZZS2_k127_7343_8	452637.Oter_2651	2.416e-109	364.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_7343_13	330214.NIDE4047	2.67e-29	121.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ZZS2_k127_7343_11	497964.CfE428DRAFT_3880	6.047e-91	312.0	COG1893@1|root,COG1893@2|Bacteria,46SK2@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
ZZS2_k127_7364453_4	1120973.AQXL01000134_gene1549	7.749e-74	257.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,2789J@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
ZZS2_k127_7364453_3	986075.CathTA2_0866	3.82e-92	309.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_7364453_0	497964.CfE428DRAFT_3359	2.373e-248	779.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
ZZS2_k127_7364453_1	1123242.JH636435_gene1839	5.594e-157	505.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7364453_2	530564.Psta_2735	2.501e-134	445.0	COG1520@1|root,COG1520@2|Bacteria,2IYI8@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7364453_5	1210884.HG799466_gene12379	3.657e-05	46.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7374008_3	221288.JH992901_gene1757	1.241e-146	482.0	COG4251@1|root,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1JH3Q@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_7374008_1	497964.CfE428DRAFT_0788	7.616e-249	776.0	COG0362@1|root,COG0362@2|Bacteria,46SDE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
ZZS2_k127_7374008_0	313606.M23134_08077	0.0	1606.0	COG0714@1|root,COG0714@2|Bacteria,4NGEG@976|Bacteroidetes,47NU2@768503|Cytophagia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
ZZS2_k127_7374008_4	344747.PM8797T_19692	1.304e-124	426.0	COG2268@1|root,COG2268@2|Bacteria,2IXVC@203682|Planctomycetes	203682|Planctomycetes	S	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7374008_2	1396141.BATP01000058_gene1993	4.408e-222	722.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
ZZS2_k127_739343_24	697282.Mettu_0542	2.723e-41	162.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
ZZS2_k127_739343_41	338963.Pcar_3159	1.42e-17	85.0	2EEQQ@1|root,338IE@2|Bacteria,1N816@1224|Proteobacteria,431SB@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_739343_35	1110697.NCAST_31_02010	4.343e-28	119.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria,4G16I@85025|Nocardiaceae	201174|Actinobacteria	O	organic hydroperoxide resistance protein	ohr	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS2_k127_739343_15	583355.Caka_1995	3.232e-99	342.0	COG0472@1|root,COG0472@2|Bacteria,46SNJ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
ZZS2_k127_739343_10	1089550.ATTH01000001_gene183	3.448e-115	389.0	COG0438@1|root,COG0438@2|Bacteria,4NKNS@976|Bacteroidetes,1FK33@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_739343_20	324925.Ppha_0562	6.83e-64	224.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wcaF	-	2.3.1.79	ko:K00661,ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
ZZS2_k127_739343_17	1122132.AQYH01000003_gene3036	1.588e-92	317.0	COG0438@1|root,COG0438@2|Bacteria,1MWEM@1224|Proteobacteria,2U1NW@28211|Alphaproteobacteria,4BCPY@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_739343_32	258533.BN977_01796	8.01e-30	136.0	COG0438@1|root,COG0438@2|Bacteria,2ICGJ@201174|Actinobacteria,23845@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_739343_26	330214.NIDE2392	8.363e-40	158.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
ZZS2_k127_739343_18	1173023.KE650771_gene3072	1.393e-89	311.0	COG2244@1|root,COG2244@2|Bacteria,1G07A@1117|Cyanobacteria,1JJZV@1189|Stigonemataceae	1117|Cyanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
ZZS2_k127_739343_25	452637.Oter_3244	5.586e-41	171.0	COG3307@1|root,COG3307@2|Bacteria,46YCP@74201|Verrucomicrobia,3K9BC@414999|Opitutae	414999|Opitutae	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_739343_8	1403819.BATR01000047_gene1377	2.568e-117	404.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46YXA@74201|Verrucomicrobia,2IVHF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
ZZS2_k127_739343_16	526218.Sterm_4083	1.007e-97	332.0	COG5505@1|root,COG5505@2|Bacteria,37B8T@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
ZZS2_k127_739343_7	575540.Isop_3614	1.381e-119	392.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_739343_42	1156937.MFUM_290038	1.548e-17	86.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,37HC9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
ZZS2_k127_739343_14	497964.CfE428DRAFT_1198	1.087e-100	332.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
ZZS2_k127_739343_22	671143.DAMO_1640	1.478e-51	196.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02841,ko:K02843,ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS2_k127_739343_40	1123070.KB899255_gene1370	1.751e-18	96.0	2EV5U@1|root,33NKM@2|Bacteria,46WDA@74201|Verrucomicrobia,2IUTJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_739343_44	1232410.KI421428_gene1029	8.553e-13	80.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,42XQR@68525|delta/epsilon subdivisions,2X2FN@28221|Deltaproteobacteria,43V6S@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
ZZS2_k127_739343_29	1210884.HG799467_gene13156	3.19e-38	151.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase,PRK
ZZS2_k127_739343_34	1205680.CAKO01000002_gene2136	1.306e-29	131.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_739343_38	1396141.BATP01000028_gene2285	8.632e-21	109.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
ZZS2_k127_739343_51	886293.Sinac_1023	0.0001651	55.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
ZZS2_k127_739343_33	1210884.HG799475_gene15289	8.69e-30	139.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Polysacc_lyase
ZZS2_k127_739343_50	1122182.KB903838_gene4056	7.981e-06	60.0	COG2133@1|root,COG2133@2|Bacteria,2HEMB@201174|Actinobacteria,4DA70@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PA14,PKD
ZZS2_k127_739343_49	1236976.JCM16418_4253	5.606e-08	67.0	COG1409@1|root,COG2041@1|root,COG3211@1|root,COG4733@1|root,COG1409@2|Bacteria,COG2041@2|Bacteria,COG3211@2|Bacteria,COG4733@2|Bacteria,1V7PQ@1239|Firmicutes,4IUC5@91061|Bacilli,277JF@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,SLH,fn3
ZZS2_k127_739343_13	449447.MAE_12400	5.9e-101	359.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	bhp	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	B_lectin,Big_3_2,Big_5,Calx-beta,DUF4347,HemolysinCabind
ZZS2_k127_739343_39	35754.JNYJ01000007_gene2933	5.962e-19	102.0	COG1404@1|root,COG2133@1|root,COG3291@1|root,COG4775@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4775@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD
ZZS2_k127_739343_4	497964.CfE428DRAFT_5370	4.387e-140	452.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
ZZS2_k127_739343_36	497964.CfE428DRAFT_4350	4.112e-22	98.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
ZZS2_k127_739343_21	640511.BC1002_6018	6.976e-52	194.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VIMJ@28216|Betaproteobacteria,1KGQV@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
ZZS2_k127_739343_47	377629.TERTU_3234	4.297e-10	70.0	2C1JV@1|root,303M7@2|Bacteria,1QQS8@1224|Proteobacteria,1RTF8@1236|Gammaproteobacteria,2PQ1W@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_739343_37	247490.KSU1_C1386	1.091e-21	106.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K20543,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	1.B.55.3	-	-	Lip_A_acyltrans,TPR_19
ZZS2_k127_739343_27	377629.TERTU_3238	2.143e-39	156.0	COG2834@1|root,COG2834@2|Bacteria,1QCKK@1224|Proteobacteria,1RW9A@1236|Gammaproteobacteria,2PPTB@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	-	-	-	-	-	-	-	-	-	LolA
ZZS2_k127_739343_2	1234664.AMRO01000004_gene2568	5.945e-169	552.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,4HDGR@91061|Bacilli	91061|Bacilli	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
ZZS2_k127_739343_23	240016.ABIZ01000001_gene2605	8.986e-44	168.0	COG0764@1|root,COG0764@2|Bacteria,46WF3@74201|Verrucomicrobia,2IVWW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
ZZS2_k127_739343_43	1121352.JHZP01000004_gene1565	1.278e-13	78.0	COG0265@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1716@2|Bacteria,1PUHS@1224|Proteobacteria,2WAU3@28216|Betaproteobacteria,2KQST@206351|Neisseriales	206351|Neisseriales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
ZZS2_k127_739343_1	886293.Sinac_6827	6.242e-263	829.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
ZZS2_k127_739343_5	330214.NIDE1620	1.214e-136	443.0	COG1118@1|root,COG1118@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K10112,ko:K16787	ko00920,ko02010,map00920,map02010	M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE,TOBE_3
ZZS2_k127_739343_6	1217718.ALOU01000041_gene56	2.341e-121	398.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,1K08X@119060|Burkholderiaceae	28216|Betaproteobacteria	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
ZZS2_k127_739343_9	1366050.N234_13040	1.014e-116	381.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,1K0GI@119060|Burkholderiaceae	28216|Betaproteobacteria	P	sulfate ABC transporter, inner membrane subunit CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
ZZS2_k127_739343_19	497964.CfE428DRAFT_0281	3.333e-71	250.0	COG2866@1|root,COG2866@2|Bacteria,46SNX@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
ZZS2_k127_739343_3	582744.Msip34_2150	2.533e-152	488.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KKVC@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
ZZS2_k127_739343_12	582744.Msip34_2149	2.798e-108	366.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,2W0HU@28216|Betaproteobacteria,2KNN1@206350|Nitrosomonadales	206350|Nitrosomonadales	P	PFAM phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
ZZS2_k127_739343_28	794903.OPIT5_00795	5.46e-39	150.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia,3K7XE@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ZZS2_k127_739343_31	1123376.AUIU01000011_gene1075	1.566e-36	145.0	COG0703@1|root,COG0703@2|Bacteria,3J0R8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
ZZS2_k127_739343_11	497964.CfE428DRAFT_4021	4.042e-114	379.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
ZZS2_k127_739343_0	452637.Oter_0972	0.0	1833.0	COG1038@1|root,COG1038@2|Bacteria	2|Bacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
ZZS2_k127_739343_45	1121405.dsmv_0737	5.891e-11	76.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
ZZS2_k127_7405651_2	583355.Caka_1736	2.297e-76	271.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_7405651_3	1288494.EBAPG3_30870	4.547e-58	214.0	COG2304@1|root,COG2304@2|Bacteria,1PXCB@1224|Proteobacteria,2WCTS@28216|Betaproteobacteria,374DH@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	Tyrosinase
ZZS2_k127_7405651_0	189753.AXAS01000052_gene6865	2.932e-127	434.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JTJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
ZZS2_k127_7425441_9	1333998.M2A_0142	1.126e-06	57.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,2U1FE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
ZZS2_k127_7425441_2	1403819.BATR01000099_gene3304	5.513e-190	608.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
ZZS2_k127_7425441_7	1403819.BATR01000118_gene4175	1.012e-26	117.0	COG3161@1|root,COG3161@2|Bacteria,46WDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7425441_3	240016.ABIZ01000001_gene3202	3.37e-183	583.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS2_k127_7425441_4	497964.CfE428DRAFT_5038	3.841e-121	400.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
ZZS2_k127_7425441_8	383372.Rcas_2774	4.319e-26	125.0	COG2374@1|root,COG3391@1|root,COG2374@2|Bacteria,COG3391@2|Bacteria,2G82K@200795|Chloroflexi,374Y1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
ZZS2_k127_7425441_6	1121441.AUCX01000002_gene2897	4.704e-42	162.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MBDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	hydrolase, HAD-superfamily, subfamily IIIA	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
ZZS2_k127_7425441_5	215803.DB30_1046	5.045e-67	239.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2YYFF@29|Myxococcales	28221|Deltaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
ZZS2_k127_7425441_0	481448.Minf_0955	8.544e-244	762.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,37G5G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
ZZS2_k127_7425441_1	1123508.JH636442_gene4219	2.168e-200	642.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
ZZS2_k127_7429227_3	497964.CfE428DRAFT_3997	5.426e-69	248.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RicinB_lectin_2
ZZS2_k127_7429227_0	497964.CfE428DRAFT_6210	1.008e-187	596.0	COG4102@1|root,COG4102@2|Bacteria,46U3G@74201|Verrucomicrobia	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7429227_2	1396141.BATP01000032_gene4278	9.545e-105	362.0	COG0515@1|root,COG0515@2|Bacteria,46TQZ@74201|Verrucomicrobia,2IV7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_7429227_4	1396141.BATP01000021_gene181	8.575e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,46TV8@74201|Verrucomicrobia,2IVT7@203494|Verrucomicrobiae	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7429227_5	469383.Cwoe_4336	1.71e-09	64.0	2B4AG@1|root,31X1X@2|Bacteria,2GWKS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7429227_1	497964.CfE428DRAFT_0845	8.41e-123	402.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS2_k127_7445313_4	497964.CfE428DRAFT_4932	2.86e-30	120.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS2_k127_7445313_2	75379.Tint_0868	4.954e-41	158.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,1KKTY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
ZZS2_k127_7445313_0	583355.Caka_2017	4.55e-179	575.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
ZZS2_k127_7445313_5	596154.Alide2_2863	1.574e-05	54.0	COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria,4AJJ9@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS2_k127_7445313_1	1163398.AJJP01000056_gene1983	1.064e-62	227.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
ZZS2_k127_7445313_3	1267534.KB906754_gene3778	7.958e-41	151.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
ZZS2_k127_7449136_0	497964.CfE428DRAFT_4539	5.566e-295	921.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
ZZS2_k127_7449136_2	1121324.CLIT_13c00200	9.234e-11	74.0	COG5607@1|root,COG5607@2|Bacteria,1U4WY@1239|Firmicutes,2510S@186801|Clostridia	186801|Clostridia	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
ZZS2_k127_7449136_3	1144275.COCOR_04885	5.318e-10	65.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WV45@28221|Deltaproteobacteria,2YZDV@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
ZZS2_k127_7449136_1	497964.CfE428DRAFT_4324	3.205e-43	160.0	2BXG3@1|root,2Z82R@2|Bacteria,46TKW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
ZZS2_k127_751057_2	1396141.BATP01000003_gene5039	9.034e-40	163.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,CarboxypepD_reg,IAT_beta,Invasin_D3,PPC
ZZS2_k127_751057_0	497964.CfE428DRAFT_0415	1.277e-170	550.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
ZZS2_k127_751057_3	1157490.EL26_19950	2.486e-20	101.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27A2H@186823|Alicyclobacillaceae	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
ZZS2_k127_751057_1	1121430.JMLG01000001_gene2105	3.478e-144	475.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25ZZN@186807|Peptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
ZZS2_k127_75232_5	357808.RoseRS_3112	2.048e-53	219.0	COG2373@1|root,COG2373@2|Bacteria,2GBMN@200795|Chloroflexi,377SP@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_75232_6	388467.A19Y_1747	4.386e-37	165.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Peptidase_S8,SdrD_B
ZZS2_k127_75232_14	138119.DSY0542	2.826e-10	76.0	COG2247@1|root,COG4932@1|root,COG2247@2|Bacteria,COG4932@2|Bacteria,1UIDD@1239|Firmicutes,25EIH@186801|Clostridia,264RK@186807|Peptococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,fn3
ZZS2_k127_75232_0	498211.CJA_0127	1.414e-145	523.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
ZZS2_k127_75232_17	1121405.dsmv_0737	3.336e-09	72.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
ZZS2_k127_75232_7	497964.CfE428DRAFT_1418	2.3e-26	115.0	COG1847@1|root,COG1847@2|Bacteria,46VYD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	R3H
ZZS2_k127_75232_2	497964.CfE428DRAFT_1419	2.656e-80	290.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
ZZS2_k127_75232_10	1217714.F975_02994	1.026e-20	100.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,3NNHN@468|Moraxellaceae	1236|Gammaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
ZZS2_k127_75232_13	690850.Desaf_1411	4.639e-11	70.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2MD4U@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
ZZS2_k127_75232_15	771875.Ferpe_1246	6.125e-10	60.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
ZZS2_k127_75232_9	497964.CfE428DRAFT_1496	4.415e-23	100.0	COG0254@1|root,COG0254@2|Bacteria,46T4W@74201|Verrucomicrobia	74201|Verrucomicrobia	J	ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
ZZS2_k127_75232_1	452637.Oter_3498	4.73e-128	422.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS2_k127_75232_4	314230.DSM3645_05160	5.445e-57	204.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS2_k127_75232_16	1192034.CAP_5689	1.271e-09	66.0	2C12A@1|root,33B7C@2|Bacteria,1NMUW@1224|Proteobacteria,434ZQ@68525|delta/epsilon subdivisions,2X93I@28221|Deltaproteobacteria,2Z1Q3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_75232_12	378806.STAUR_7570	1.033e-16	88.0	2E40T@1|root,32YXK@2|Bacteria,1N95U@1224|Proteobacteria,43E2C@68525|delta/epsilon subdivisions,2WZHB@28221|Deltaproteobacteria,2Z25B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_75232_11	215803.DB30_3427	7.201e-20	95.0	COG3682@1|root,COG3682@2|Bacteria,1N6UP@1224|Proteobacteria,43DK7@68525|delta/epsilon subdivisions,2X8RD@28221|Deltaproteobacteria,2Z0IP@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_75232_8	886293.Sinac_7013	1.689e-25	115.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
ZZS2_k127_75232_3	616991.JPOO01000003_gene1589	8.305e-59	221.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,1I081@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_7538220_4	521674.Plim_1247	3.646e-35	139.0	COG1225@1|root,COG1225@2|Bacteria,2IZIQ@203682|Planctomycetes	203682|Planctomycetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS2_k127_7538220_0	1142394.PSMK_12790	6.313e-83	287.0	COG0673@1|root,COG0673@2|Bacteria,2IY6G@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7538220_1	1142394.PSMK_13110	2.348e-74	259.0	COG1082@1|root,COG1082@2|Bacteria,2IXZ6@203682|Planctomycetes	203682|Planctomycetes	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_7538220_2	1403819.BATR01000054_gene1700	3.243e-74	254.0	COG0431@1|root,COG0431@2|Bacteria,46SXE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS2_k127_7538220_5	755732.Fluta_1212	1.936e-28	132.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_7538220_3	216594.MMAR_0242	1.51e-50	200.0	COG0657@1|root,COG0823@1|root,COG0657@2|Bacteria,COG0823@2|Bacteria,2I40M@201174|Actinobacteria,233DD@1762|Mycobacteriaceae	201174|Actinobacteria	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE
ZZS2_k127_7551278_6	1396418.BATQ01000046_gene6123	5.396e-17	90.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,2IUEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
ZZS2_k127_7551278_1	886293.Sinac_7310	2.374e-106	353.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_7551278_3	497964.CfE428DRAFT_2982	1.18e-54	205.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_7551278_2	1396141.BATP01000060_gene4629	6.475e-72	269.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
ZZS2_k127_7551278_7	123899.JPQP01000009_gene307	6.155e-15	89.0	COG4252@1|root,COG5002@1|root,COG4252@2|Bacteria,COG5002@2|Bacteria,1MUHS@1224|Proteobacteria,2VIGN@28216|Betaproteobacteria,3T2NC@506|Alcaligenaceae	28216|Betaproteobacteria	T	His Kinase A phosphoacceptor domain-containing protein 13	phoR_2	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,PAS_4
ZZS2_k127_7551278_0	1396141.BATP01000060_gene4727	8.131e-252	820.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_7551278_8	1089547.KB913013_gene3997	5.319e-06	60.0	COG1520@1|root,COG3210@1|root,COG3386@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria,4NTNN@976|Bacteroidetes,47K8B@768503|Cytophagia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
ZZS2_k127_7551278_5	449447.MAE_12430	2.343e-37	163.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
ZZS2_k127_7551278_4	314278.NB231_14333	6.481e-41	164.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria,1S6QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
ZZS2_k127_7595991_0	497964.CfE428DRAFT_3146	2.713e-235	744.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	thiamine pyrophosphate protein TPP binding domain protein	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS2_k127_7595991_2	357808.RoseRS_2309	7.575e-57	214.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7595991_3	349741.Amuc_1517	3.264e-43	165.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_7595991_1	382464.ABSI01000011_gene2968	1.822e-70	270.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_760359_1	497964.CfE428DRAFT_1861	8.721e-35	155.0	COG1595@1|root,COG4194@1|root,COG1595@2|Bacteria,COG4194@2|Bacteria,46TQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2,TonB_C
ZZS2_k127_760359_0	344747.PM8797T_09024	2.538e-50	206.0	COG2373@1|root,COG4219@1|root,COG2373@2|Bacteria,COG4219@2|Bacteria,2J096@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56
ZZS2_k127_760359_2	452637.Oter_0659	3.588e-28	126.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yprA	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS2_k127_7613185_2	1379698.RBG1_1C00001G0123	2.753e-92	310.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
ZZS2_k127_7613185_4	1123322.KB904708_gene112	5.86e-15	87.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_7613185_3	240016.ABIZ01000001_gene2936	3.153e-76	267.0	COG3391@1|root,COG3391@2|Bacteria,46YXB@74201|Verrucomicrobia,2IV65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7613185_1	335543.Sfum_3555	1.272e-124	425.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_7613185_0	215803.DB30_4326	2.608e-152	520.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YU7C@29|Myxococcales	28221|Deltaproteobacteria	KL	helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
ZZS2_k127_7633337_1	118166.JH976537_gene2134	2.326e-18	92.0	COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1HBYN@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
ZZS2_k127_7633337_0	1120963.KB894499_gene422	1.037e-221	764.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_7633337_2	1122179.KB890417_gene3254	1.439e-17	96.0	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1IVJJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Salmonella virulence plasmid 65kDa B protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
ZZS2_k127_7636865_2	497964.CfE428DRAFT_2825	8.376e-89	297.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
ZZS2_k127_7636865_0	497964.CfE428DRAFT_2824	0.0	2681.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7636865_1	1396141.BATP01000033_gene4252	3.819e-113	385.0	COG2312@1|root,COG2312@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_7646280_4	1463820.JOGW01000021_gene133	3.625e-27	116.0	COG0451@1|root,COG0451@2|Bacteria,2GN75@201174|Actinobacteria	201174|Actinobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_7646280_3	794903.OPIT5_27960	9.033e-41	166.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,3K7YX@414999|Opitutae	414999|Opitutae	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
ZZS2_k127_7646280_2	497964.CfE428DRAFT_6143	1.165e-56	221.0	COG0163@1|root,COG0163@2|Bacteria,46V9E@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ZZS2_k127_7646280_1	644968.DFW101_1764	8.853e-85	295.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,42Z4V@68525|delta/epsilon subdivisions,2WU31@28221|Deltaproteobacteria,2MFW4@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
ZZS2_k127_7646280_0	497964.CfE428DRAFT_1708	6.293e-165	528.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
ZZS2_k127_7662744_9	1100720.ALKN01000043_gene2663	2.553e-09	63.0	COG2105@1|root,COG2105@2|Bacteria,1NIAM@1224|Proteobacteria,2VVWY@28216|Betaproteobacteria,4AFR7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
ZZS2_k127_7662744_4	443143.GM18_2599	4.82e-43	171.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43UDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS2_k127_7662744_3	1232410.KI421421_gene3418	2.026e-66	239.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42YJC@68525|delta/epsilon subdivisions,2WTKU@28221|Deltaproteobacteria,43TDB@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS2_k127_7662744_5	1122217.KB899568_gene793	3.181e-37	151.0	COG0767@1|root,COG0767@2|Bacteria,1U95A@1239|Firmicutes,4H2EU@909932|Negativicutes	909932|Negativicutes	Q	Belongs to the MlaE permease family	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS2_k127_7662744_2	269799.Gmet_1270	1.386e-68	252.0	COG3170@1|root,COG3170@2|Bacteria,1MY6X@1224|Proteobacteria,42TBE@68525|delta/epsilon subdivisions,2WPBV@28221|Deltaproteobacteria,43U5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7662744_1	1267534.KB906754_gene3777	5.592e-81	277.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
ZZS2_k127_7662744_0	1267534.KB906754_gene3776	5.075e-154	497.0	COG1005@1|root,COG1005@2|Bacteria,3Y6TS@57723|Acidobacteria,2JKJQ@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
ZZS2_k127_7662744_7	240015.ACP_2571	1.292e-32	134.0	COG0839@1|root,COG0839@2|Bacteria,3Y84Z@57723|Acidobacteria,2JN7E@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
ZZS2_k127_7662744_6	1267534.KB906754_gene3774	1.886e-35	138.0	COG0713@1|root,COG0713@2|Bacteria,3Y835@57723|Acidobacteria,2JN5T@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
ZZS2_k127_7680140_10	1396141.BATP01000060_gene4768	8.188e-34	138.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7680140_12	326427.Cagg_3284	8.413e-18	97.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
ZZS2_k127_7680140_7	278957.ABEA03000004_gene4502	1.87e-54	211.0	COG1262@1|root,COG1262@2|Bacteria,46VAM@74201|Verrucomicrobia,3K9HB@414999|Opitutae	414999|Opitutae	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,VPEP
ZZS2_k127_7680140_11	655815.ZPR_4181	2.784e-22	109.0	COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,1HZX4@117743|Flavobacteriia	976|Bacteroidetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
ZZS2_k127_7680140_8	1237149.C900_00073	1.769e-45	172.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_00073|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7680140_3	1237149.C900_00072	1.391e-102	340.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
ZZS2_k127_7680140_0	1237149.C900_00071	1.313e-314	980.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS2_k127_7680140_4	398525.KB900701_gene1105	7.349e-87	293.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
ZZS2_k127_7680140_2	316067.Geob_1840	2.827e-114	372.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS2_k127_7680140_1	153721.MYP_3853	8.336e-172	567.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_7680140_9	1280390.CBQR020000166_gene4413	5.093e-43	181.0	COG4733@1|root,COG4733@2|Bacteria,1TQB3@1239|Firmicutes,4HU7T@91061|Bacilli,26RV2@186822|Paenibacillaceae	91061|Bacilli	G	Cellulose 1,4-beta-cellobiosidase	bglC3	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Glyco_hydro_48,fn3
ZZS2_k127_7680140_13	497964.CfE428DRAFT_1819	0.0006535	52.0	2DFEQ@1|root,2ZRKC@2|Bacteria,46WVM@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7680140_5	1340493.JNIF01000003_gene1629	2.587e-83	286.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7680140_6	1122135.KB893138_gene1109	2.947e-55	196.0	COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,2U3P5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_7708290_21	1396141.BATP01000030_gene3637	0.0001807	57.0	COG2133@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3828@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,ThuA
ZZS2_k127_7708290_13	1121920.AUAU01000009_gene1881	1.299e-29	140.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_7708290_2	1396141.BATP01000020_gene50	2.65e-262	890.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_7708290_15	1283283.ATXA01000005_gene2022	1.141e-15	94.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
ZZS2_k127_7708290_18	1396141.BATP01000044_gene1513	1.791e-09	73.0	COG1082@1|root,COG1621@1|root,COG3209@1|root,COG3291@1|root,COG4733@1|root,COG1082@2|Bacteria,COG1621@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	AP_endonuc_2,F5_F8_type_C,Laminin_G_3,PKD
ZZS2_k127_7708290_20	1288494.EBAPG3_22490	3.191e-05	53.0	28UGW@1|root,2ZGMQ@2|Bacteria,1PAJG@1224|Proteobacteria,2W686@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7708290_10	1177154.Y5S_00222	1.569e-40	165.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1RQJV@1236|Gammaproteobacteria,1XME4@135619|Oceanospirillales	135619|Oceanospirillales	S	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_7708290_19	713586.KB900536_gene1304	3.367e-09	69.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
ZZS2_k127_7708290_9	471854.Dfer_0576	6.15e-51	193.0	COG0454@1|root,COG0456@2|Bacteria,4NT7Q@976|Bacteroidetes,47VTT@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS2_k127_7708290_4	497964.CfE428DRAFT_1053	3.319e-215	694.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
ZZS2_k127_7708290_12	107636.JQNK01000007_gene4512	2.772e-32	137.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2UHB3@28211|Alphaproteobacteria,3706F@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS2_k127_7708290_16	661478.OP10G_2517	6.08e-15	89.0	2EQYW@1|root,33IIJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7708290_6	1123242.JH636435_gene1286	2.531e-110	366.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_7708290_11	1210884.HG799468_gene13554	8.382e-39	148.0	COG1725@1|root,COG1725@2|Bacteria,2J03Y@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
ZZS2_k127_7708290_8	1192034.CAP_8404	2.272e-76	272.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
ZZS2_k127_7708290_7	861299.J421_5839	4.62e-87	318.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
ZZS2_k127_7708290_3	861299.J421_1753	1.282e-258	840.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_7708290_5	1396418.BATQ01000046_gene6113	4.593e-186	589.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
ZZS2_k127_7708290_1	886293.Sinac_2812	0.0	1169.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX57@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Cytochrom_C,ThuA
ZZS2_k127_7708290_14	459349.CLOAM0816	4.843e-27	115.0	COG3118@1|root,COG3118@2|Bacteria,2NPNZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the thioredoxin family	trxA	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
ZZS2_k127_7708290_0	452637.Oter_3813	0.0	1384.0	COG0841@1|root,COG0841@2|Bacteria,46U0U@74201|Verrucomicrobia,3K72W@414999|Opitutae	414999|Opitutae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18299,ko:K18902	-	M00641,M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.16	-	-	ACR_tran
ZZS2_k127_7709952_0	452637.Oter_0358	5.361e-80	294.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46YZC@74201|Verrucomicrobia,3K9WB@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_7709952_1	497964.CfE428DRAFT_0064	4.466e-39	153.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_7710047_10	575540.Isop_1317	2.454e-13	84.0	COG3386@1|root,COG3420@1|root,COG3386@2|Bacteria,COG3420@2|Bacteria,2J2MQ@203682|Planctomycetes	203682|Planctomycetes	P	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_7710047_6	886293.Sinac_0541	5.068e-128	417.0	COG0546@1|root,COG0546@2|Bacteria,2IZVE@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS2_k127_7710047_4	497964.CfE428DRAFT_0965	2.05e-132	432.0	COG1082@1|root,COG1082@2|Bacteria,46UT7@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_7710047_8	1123070.KB899250_gene603	3.83e-96	324.0	COG0709@1|root,COG0709@2|Bacteria	2|Bacteria	E	selenide, water dikinase activity	selD	-	2.7.9.3,2.8.1.7	ko:K01008,ko:K04487	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122	-	R03595,R07460,R11528,R11529	RC00002,RC01789,RC02313,RC02878	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	AIRS,AIRS_C,Pyr_redox_2
ZZS2_k127_7710047_7	1123070.KB899248_gene241	1.412e-121	404.0	COG1921@1|root,COG1921@2|Bacteria	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	selA	GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006	Se-cys_synth_N,SelA
ZZS2_k127_7710047_9	497964.CfE428DRAFT_6620	2.232e-73	254.0	COG2360@1|root,COG2360@2|Bacteria,46VHR@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
ZZS2_k127_7710047_1	886293.Sinac_6965	1.497e-190	607.0	COG0739@1|root,COG1506@1|root,COG3291@1|root,COG0739@2|Bacteria,COG1506@2|Bacteria,COG3291@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
ZZS2_k127_7710047_0	243090.RB13132	1.393e-217	685.0	COG4102@1|root,COG4102@2|Bacteria,2IXKP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7710047_2	243090.RB13137	9.02e-174	573.0	COG2010@1|root,COG2010@2|Bacteria,2IY1J@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_7710047_3	314230.DSM3645_04730	3.977e-144	471.0	COG0673@1|root,COG0673@2|Bacteria,2IYHX@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_7710047_5	497964.CfE428DRAFT_6006	1.644e-130	425.0	COG0673@1|root,COG0673@2|Bacteria,46TKX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_7712484_13	639030.JHVA01000001_gene2022	1.132e-28	130.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_7712484_8	1356854.N007_10430	9.222e-90	299.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
ZZS2_k127_7712484_3	497964.CfE428DRAFT_6473	3.669e-139	449.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
ZZS2_k127_7712484_1	497964.CfE428DRAFT_6472	3.825e-178	563.0	COG0022@1|root,COG0022@2|Bacteria,46UID@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
ZZS2_k127_7712484_2	497964.CfE428DRAFT_6471	8.21e-167	536.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS2_k127_7712484_16	261292.Nit79A3_0274	9.817e-08	57.0	COG3668@1|root,COG3668@2|Bacteria,1PYVC@1224|Proteobacteria,2WDZV@28216|Betaproteobacteria,3749Y@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Plasmid stabilisation system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
ZZS2_k127_7712484_4	886293.Sinac_2494	4.996e-137	448.0	COG2211@1|root,COG2211@2|Bacteria,2IWTX@203682|Planctomycetes	203682|Planctomycetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
ZZS2_k127_7712484_6	1303518.CCALI_02044	1.072e-127	423.0	2EE91@1|root,3383F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7712484_12	1396141.BATP01000060_gene4657	4.788e-35	158.0	COG2010@1|root,COG2312@1|root,COG3204@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD,Laminin_G_3
ZZS2_k127_7712484_7	313603.FB2170_10111	5.228e-120	439.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_7712484_14	1396141.BATP01000042_gene1928	9.119e-13	84.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_7712484_15	1396141.BATP01000045_gene1848	6.978e-08	68.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_7712484_10	1121920.AUAU01000009_gene1881	3.891e-51	211.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_7712484_11	573061.Clocel_1966	3.046e-35	159.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_7712484_17	269798.CHU_3727	4.001e-05	59.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_8
ZZS2_k127_7712484_0	1396141.BATP01000034_gene4198	3.562e-253	878.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_7712484_9	1121920.AUAU01000009_gene1881	2.285e-60	243.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
ZZS2_k127_7712484_18	439235.Dalk_1026	0.000106	55.0	COG3420@1|root,COG3420@2|Bacteria,1NGNA@1224|Proteobacteria,43156@68525|delta/epsilon subdivisions,2WW9W@28221|Deltaproteobacteria,2MNX1@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_7712484_5	1396141.BATP01000034_gene4198	5.542e-133	462.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_77136_0	1449049.JONW01000005_gene1182	0.0	1044.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,2TT7K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	formate C-acetyltransferase glycine radical	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
ZZS2_k127_77136_1	864069.MicloDRAFT_00035630	4.844e-263	819.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2UQSP@28211|Alphaproteobacteria,1JZ52@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Serine dehydratase beta chain	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha,SDH_beta
ZZS2_k127_77136_2	794903.OPIT5_02510	5.745e-104	349.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
ZZS2_k127_773194_1	530564.Psta_1668	2.032e-119	398.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_773194_2	296591.Bpro_0725	0.0005772	48.0	2B3U0@1|root,31WHT@2|Bacteria,1RIS2@1224|Proteobacteria,2VSJF@28216|Betaproteobacteria,4AI0N@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_773194_0	1487953.JMKF01000022_gene2503	1.824e-120	405.0	COG0673@1|root,COG0673@2|Bacteria,1G18V@1117|Cyanobacteria,1HG44@1150|Oscillatoriales	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.335,1.1.99.28	ko:K00118,ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7735203_12	1168059.KB899087_gene3163	1.508e-34	154.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3EZXC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM60,HemolysinCabind,Metallophos,PPC,Peptidase_M10_C
ZZS2_k127_7735203_11	935836.JAEL01000008_gene3952	3.741e-35	156.0	COG1524@1|root,COG5492@1|root,COG1524@2|Bacteria,COG5492@2|Bacteria,1V7WK@1239|Firmicutes,4IETN@91061|Bacilli,1ZEHY@1386|Bacillus	91061|Bacilli	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Laminin_G_3,Phosphodiest
ZZS2_k127_7735203_15	575540.Isop_1614	1.048e-16	94.0	COG2373@1|root,COG2373@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
ZZS2_k127_7735203_6	1268622.AVS7_04060	9.699e-77	279.0	COG4733@1|root,COG4733@2|Bacteria,1QVB2@1224|Proteobacteria	1224|Proteobacteria	S	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,fn3
ZZS2_k127_7735203_10	1056816.JAFQ01000004_gene6788	2.814e-35	137.0	COG3224@1|root,COG3224@2|Bacteria,2GQKQ@201174|Actinobacteria,4G3EY@85025|Nocardiaceae	201174|Actinobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
ZZS2_k127_7735203_18	1123070.KB899250_gene635	0.000314	48.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
ZZS2_k127_7735203_4	349741.Amuc_0792	6.526e-112	373.0	COG0535@1|root,COG0535@2|Bacteria,46T4P@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART Elongator protein 3 MiaB NifB	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
ZZS2_k127_7735203_8	1288963.ADIS_1296	2.209e-55	220.0	COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,47JRH@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
ZZS2_k127_7735203_3	497964.CfE428DRAFT_5616	8.433e-128	424.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
ZZS2_k127_7735203_7	56780.SYN_00668	8.595e-62	222.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
ZZS2_k127_7735203_9	240292.Ava_4725	8.638e-55	222.0	COG2931@1|root,COG2931@2|Bacteria,1GIZT@1117|Cyanobacteria,1HMI7@1161|Nostocales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VCBS
ZZS2_k127_7735203_14	227882.SAV_432	8.142e-17	96.0	COG3210@1|root,COG3210@2|Bacteria,2I4P8@201174|Actinobacteria	201174|Actinobacteria	U	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_7735203_1	1122137.AQXF01000002_gene460	9.913e-199	637.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS2_k127_7735203_2	497964.CfE428DRAFT_5429	2.675e-139	454.0	COG1520@1|root,COG1520@2|Bacteria,46TI7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7735203_13	682795.AciX8_3725	5.786e-17	96.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
ZZS2_k127_7735203_17	1296415.JACC01000064_gene2544	2.499e-05	58.0	COG0412@1|root,COG1470@1|root,COG0412@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.1.1.45	ko:K01061,ko:K11031	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,ko02024,map00361,map00364,map00623,map01100,map01110,map01120,map01130,map02024	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000,ko02042	-	-	-	DLH,F5_F8_type_C,RicinB_lectin_2,Ricin_B_lectin,Thiol_cytolys_C,Thiol_cytolysin,YSIRK_signal
ZZS2_k127_7735203_5	278957.ABEA03000029_gene1249	6.773e-91	334.0	COG4719@1|root,COG4719@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,SdrD_B
ZZS2_k127_7735203_0	794903.OPIT5_20790	0.0	1379.0	COG3188@1|root,COG3188@2|Bacteria	2|Bacteria	NU	fimbrial usher porin activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,DUF11,Plug,SdrD_B,TonB_dep_Rec
ZZS2_k127_7735203_16	1177181.T9A_00640	1.128e-13	76.0	COG1470@1|root,COG1470@2|Bacteria,1MVJN@1224|Proteobacteria,1S0BN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS2_k127_7738485_1	272123.Anacy_0345	3.482e-61	214.0	COG5483@1|root,COG5483@2|Bacteria,1G5J1@1117|Cyanobacteria,1HP7V@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
ZZS2_k127_7738485_2	365044.Pnap_0404	7.279e-18	90.0	COG4719@1|root,COG4719@2|Bacteria,1MZ71@1224|Proteobacteria,2VVMB@28216|Betaproteobacteria,4AHXQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS2_k127_7738485_0	278957.ABEA03000032_gene2684	1.577e-154	516.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DUF11,NPCBM_assoc
ZZS2_k127_7744557_6	575540.Isop_3726	8.205e-142	460.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ZZS2_k127_7744557_25	1202962.KB907159_gene3249	2.026e-20	103.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1SZ0I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
ZZS2_k127_7744557_14	497964.CfE428DRAFT_5469	1.694e-88	307.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
ZZS2_k127_7744557_9	382464.ABSI01000020_gene121	3.409e-108	369.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
ZZS2_k127_7744557_3	382464.ABSI01000020_gene122	1.561e-201	659.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,46TS1@74201|Verrucomicrobia,2ITZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_7744557_11	382464.ABSI01000020_gene123	1.148e-104	354.0	COG3437@1|root,COG3437@2|Bacteria,46Z3C@74201|Verrucomicrobia,2IUIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
ZZS2_k127_7744557_12	1288963.ADIS_2727	3.915e-103	355.0	COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,47K44@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_7744557_20	497964.CfE428DRAFT_5269	6.079e-66	238.0	COG1363@1|root,COG1363@2|Bacteria,46T0I@74201|Verrucomicrobia	74201|Verrucomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
ZZS2_k127_7744557_18	871968.DESME_13210	7.044e-75	266.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ZZS2_k127_7744557_26	1297742.A176_04855	2.505e-20	92.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria,2Z1Q1@29|Myxococcales	28221|Deltaproteobacteria	K	Cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS2_k127_7744557_13	575540.Isop_2558	1.507e-100	353.0	COG4927@1|root,COG4927@2|Bacteria,2IYD9@203682|Planctomycetes	203682|Planctomycetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
ZZS2_k127_7744557_19	497964.CfE428DRAFT_2594	3.784e-70	247.0	COG2138@1|root,COG2138@2|Bacteria,46SPE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
ZZS2_k127_7744557_24	886293.Sinac_2505	5.133e-27	116.0	2ESSA@1|root,33KAQ@2|Bacteria,2J1KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7744557_16	1121033.AUCF01000001_gene2030	1.319e-82	284.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_7744557_4	1247963.JPHU01000001_gene2061	2.35e-149	486.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_7744557_23	452637.Oter_2257	1.804e-29	134.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	dsbC	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0055114,GO:0140096	5.3.4.1	ko:K01829,ko:K03673,ko:K03805,ko:K03981,ko:K12228	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko02044,ko03110	3.A.7.10.1,3.A.7.11.1	-	iE2348C_1286.E2348C_3146,iEC042_1314.EC042_3104,iECO111_1330.ECO111_0636,iECO26_1355.ECO26_0680,iEcE24377_1341.EcE24377A_0625,iEcSMS35_1347.EcSMS35_3026,iG2583_1286.G2583_0768,iPC815.YPO0891,iSFV_1184.SFV_2941,iSF_1195.SF2879,iSFxv_1172.SFxv_3158,iS_1188.S3078	DsbC_N,Thioredoxin_2,Thioredoxin_4,VKOR
ZZS2_k127_7744557_10	1192034.CAP_8113	3.885e-105	367.0	COG1409@1|root,COG2133@1|root,COG4932@1|root,COG5563@1|root,COG1409@2|Bacteria,COG2133@2|Bacteria,COG4932@2|Bacteria,COG5563@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
ZZS2_k127_7744557_28	321327.CYA_2128	0.0005152	51.0	COG0457@1|root,COG0457@2|Bacteria,1GRNS@1117|Cyanobacteria,1H2HW@1129|Synechococcus	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
ZZS2_k127_7744557_22	243090.RB5081	1.192e-30	127.0	COG1595@1|root,COG1595@2|Bacteria,2J0HK@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7744557_8	497964.CfE428DRAFT_4331	1.905e-108	371.0	COG3712@1|root,COG3712@2|Bacteria,46TYW@74201|Verrucomicrobia	2|Bacteria	PT	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,Laminin_G_3
ZZS2_k127_7744557_7	234267.Acid_2103	6.647e-138	451.0	COG2382@1|root,COG2382@2|Bacteria,3Y2ZN@57723|Acidobacteria	2|Bacteria	GP	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Glyco_hydro_10
ZZS2_k127_7744557_5	1396141.BATP01000001_gene5356	3.233e-142	464.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_7744557_15	886293.Sinac_2762	8.098e-87	293.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,COG3828@2|Bacteria,2IX57@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Cytochrom_C,ThuA
ZZS2_k127_7744557_1	1403819.BATR01000002_gene103	9.258e-238	764.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46UMZ@74201|Verrucomicrobia,2IV99@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
ZZS2_k127_7744557_27	1123277.KB893206_gene3409	1.637e-13	80.0	COG3507@1|root,COG3507@2|Bacteria,4NKNH@976|Bacteroidetes,47K70@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7744557_17	926549.KI421517_gene2826	2.28e-79	280.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47KU5@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
ZZS2_k127_7744557_2	1396141.BATP01000001_gene5347	2.734e-217	682.0	COG2211@1|root,COG2211@2|Bacteria,46U6G@74201|Verrucomicrobia,2IV97@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
ZZS2_k127_7744557_0	452637.Oter_3545	1.463e-301	933.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	xynB	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	DUF1349,Glyco_hydro_43
ZZS2_k127_7744557_21	234267.Acid_6845	1.468e-50	188.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria,3Y83C@57723|Acidobacteria	57723|Acidobacteria	I	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
ZZS2_k127_7757262_8	1340493.JNIF01000003_gene3435	2.456e-23	101.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
ZZS2_k127_7757262_4	545694.TREPR_0418	1.376e-61	224.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
ZZS2_k127_7757262_10	1449347.JQLN01000006_gene2883	4.726e-16	92.0	COG3511@1|root,COG5520@1|root,COG3511@2|Bacteria,COG5520@2|Bacteria,2GQGM@201174|Actinobacteria,2M4PK@2063|Kitasatospora	201174|Actinobacteria	M	amine dehydrogenase activity	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
ZZS2_k127_7757262_6	1121011.AUCB01000071_gene3108	5.856e-50	198.0	COG1524@1|root,COG1524@2|Bacteria,4NM2J@976|Bacteroidetes,1I2KP@117743|Flavobacteriia,23I4P@178469|Arenibacter	976|Bacteroidetes	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4983,Hemopexin,Laminin_G_3,Phosphodiest
ZZS2_k127_7757262_9	1123508.JH636442_gene4217	1.138e-21	107.0	2DUGB@1|root,33QI7@2|Bacteria,2J2DI@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7757262_11	497964.CfE428DRAFT_3331	2.486e-15	81.0	COG1135@1|root,COG1135@2|Bacteria,46WAD@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	NIL
ZZS2_k127_7757262_3	661478.OP10G_2644	9.183e-84	286.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	MA20_09190	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS2_k127_7757262_2	661478.OP10G_2641	1.707e-85	294.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS2_k127_7757262_1	497964.CfE428DRAFT_1905	5.816e-100	335.0	COG1045@1|root,COG1045@2|Bacteria,46S5J@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
ZZS2_k127_7757262_12	1123242.JH636435_gene795	3.861e-11	64.0	COG2960@1|root,COG2960@2|Bacteria,2IX5N@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_7757262_7	247490.KSU1_A0074	3.432e-39	153.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS2_k127_7757262_5	530564.Psta_4691	1.421e-55	207.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS2_k127_7757262_0	1227739.Hsw_PA0012	4.288e-194	639.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
ZZS2_k127_7757731_7	335543.Sfum_2279	3.742e-05	53.0	COG1404@1|root,COG1404@2|Bacteria,1PFBD@1224|Proteobacteria,43A1G@68525|delta/epsilon subdivisions,2X9U2@28221|Deltaproteobacteria,2MSGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_7757731_1	1267535.KB906767_gene1815	7.851e-193	628.0	COG1262@1|root,COG4409@1|root,COG1262@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FGE-sulfatase
ZZS2_k127_7757731_3	861299.J421_0709	6.832e-66	230.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	LOR
ZZS2_k127_7757731_0	583355.Caka_2007	1.198e-289	923.0	COG0553@1|root,COG0553@2|Bacteria,46U72@74201|Verrucomicrobia,3K7EW@414999|Opitutae	414999|Opitutae	L	RNA polymerase recycling family C-terminal	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
ZZS2_k127_7757731_2	330214.NIDE0541	3.736e-67	238.0	COG3145@1|root,COG3145@2|Bacteria	2|Bacteria	L	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
ZZS2_k127_7757731_6	330214.NIDE0736	2.157e-39	161.0	COG0558@1|root,COG1208@1|root,COG0558@2|Bacteria,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ZZS2_k127_7757731_4	330214.NIDE0737	8.303e-49	189.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS2_k127_7757731_5	211165.AJLN01000081_gene933	7.899e-44	172.0	COG1213@1|root,COG1213@2|Bacteria	2|Bacteria	M	nucleotidyl transferase	-	-	2.7.7.74	ko:K07281	ko00562,map00562	-	R09669	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTP_transferase
ZZS2_k127_7774559_24	1403819.BATR01000100_gene3342	1.513e-41	163.0	COG2165@1|root,COG2165@2|Bacteria,46W6U@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_7774559_50	933262.AXAM01000156_gene1041	4.424e-09	67.0	2DV5M@1|root,33U68@2|Bacteria,1NUIA@1224|Proteobacteria,42ZFX@68525|delta/epsilon subdivisions,2WV1Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_11	452637.Oter_2514	1.399e-92	330.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46VP5@74201|Verrucomicrobia,3K8IM@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_7774559_29	1121957.ATVL01000007_gene2357	9.202e-35	142.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
ZZS2_k127_7774559_26	382464.ABSI01000020_gene153	8.356e-40	157.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_21	1396141.BATP01000023_gene616	2.21e-46	180.0	2B5SN@1|root,31YNB@2|Bacteria,46XHC@74201|Verrucomicrobia,2IVXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_23	382464.ABSI01000020_gene153	1.626e-43	172.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_16	1403819.BATR01000092_gene2785	1.018e-65	235.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia,2IWA1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	LytB protein	-	-	-	-	-	-	-	-	-	-	-	-	LYTB
ZZS2_k127_7774559_36	1340493.JNIF01000003_gene1913	6.985e-22	105.0	COG1846@1|root,COG1846@2|Bacteria,3Y7YY@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
ZZS2_k127_7774559_46	240016.ABIZ01000001_gene4454	3.492e-11	72.0	2BJXT@1|root,32EAA@2|Bacteria,46XIQ@74201|Verrucomicrobia,2IW0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_25	497964.CfE428DRAFT_1107	8.841e-41	161.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7774559_5	497964.CfE428DRAFT_0922	2.831e-123	405.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_7774559_18	313603.FB2170_10111	1.363e-54	223.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_7774559_9	1396141.BATP01000043_gene1929	2.757e-100	374.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_7774559_37	1396141.BATP01000059_gene2520	1.063e-21	114.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
ZZS2_k127_7774559_52	984262.SGRA_2790	2.474e-06	63.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1IPQ3@117747|Sphingobacteriia	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
ZZS2_k127_7774559_41	755732.Fluta_1212	2.303e-18	103.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_7774559_44	401053.AciPR4_3551	3.605e-12	82.0	COG3250@1|root,COG3250@2|Bacteria,3Y8XN@57723|Acidobacteria,2JNSW@204432|Acidobacteriia	204432|Acidobacteriia	G	Beta-1,3-glucanase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_64
ZZS2_k127_7774559_54	1123242.JH636434_gene4798	0.0009976	49.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_7774559_47	1123508.JH636439_gene977	1.269e-10	64.0	COG2010@1|root,COG2010@2|Bacteria,2IYKH@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_7774559_31	794903.OPIT5_07630	2.105e-32	136.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
ZZS2_k127_7774559_13	1144275.COCOR_04284	1.707e-85	294.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
ZZS2_k127_7774559_22	717605.Theco_1139	3.41e-46	176.0	COG0352@1|root,COG2104@1|root,COG0352@2|Bacteria,COG2104@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,26UCZ@186822|Paenibacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
ZZS2_k127_7774559_1	497964.CfE428DRAFT_2953	2.701e-207	653.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS2_k127_7774559_28	583355.Caka_1863	1.161e-36	143.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,3K861@414999|Opitutae	414999|Opitutae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
ZZS2_k127_7774559_20	864069.MicloDRAFT_00019440	3.02e-48	177.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,1JU95@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
ZZS2_k127_7774559_43	927677.ALVU02000001_gene2273	1.215e-14	87.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1H52W@1142|Synechocystis	1117|Cyanobacteria	M	O-Antigen ligase	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
ZZS2_k127_7774559_27	243231.GSU2230	9.704e-37	152.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43UA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
ZZS2_k127_7774559_32	1396141.BATP01000004_gene5888	2.502e-32	131.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_14	497964.CfE428DRAFT_2596	5.184e-82	288.0	COG0402@1|root,COG0402@2|Bacteria,46TB5@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_7774559_53	1033810.HLPCO_002547	0.0002362	49.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
ZZS2_k127_7774559_0	794903.OPIT5_26155	1.857e-282	887.0	COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,3K8JV@414999|Opitutae	414999|Opitutae	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase
ZZS2_k127_7774559_35	1122604.JONR01000003_gene1415	7.473e-24	111.0	2E7GU@1|root,331ZI@2|Bacteria,1NEDQ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4184)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184
ZZS2_k127_7774559_15	1254432.SCE1572_38850	8.207e-73	270.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
ZZS2_k127_7774559_12	452637.Oter_1143	2.531e-88	304.0	COG3842@1|root,COG3842@2|Bacteria,46UM0@74201|Verrucomicrobia,3K7P9@414999|Opitutae	414999|Opitutae	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
ZZS2_k127_7774559_8	1123242.JH636435_gene1377	3.745e-103	347.0	COG1611@1|root,COG1611@2|Bacteria,2IXIR@203682|Planctomycetes	203682|Planctomycetes	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS2_k127_7774559_45	207559.Dde_0512	7.915e-12	72.0	COG4681@1|root,COG4681@2|Bacteria,1Q83U@1224|Proteobacteria,436UG@68525|delta/epsilon subdivisions,2X1IC@28221|Deltaproteobacteria,2MF4B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YaeQ protein	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
ZZS2_k127_7774559_40	203122.Sde_3876	3.57e-19	104.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
ZZS2_k127_7774559_39	1336803.PHEL49_1867	2.708e-19	104.0	COG2312@1|root,COG3537@1|root,COG4935@1|root,COG5337@1|root,COG2312@2|Bacteria,COG3537@2|Bacteria,COG4935@2|Bacteria,COG5337@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,3VX3A@52959|Polaribacter	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
ZZS2_k127_7774559_17	1396141.BATP01000034_gene4198	1.4e-56	226.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_7774559_49	1218084.BBJK01000006_gene797	1.436e-09	68.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria,1K1ZV@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_7774559_7	478741.JAFS01000002_gene596	2.29e-119	398.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,37G7B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS2_k127_7774559_2	240016.ABIZ01000001_gene228	3.805e-148	481.0	COG1680@1|root,COG5297@1|root,COG1680@2|Bacteria,COG5297@2|Bacteria,46TK0@74201|Verrucomicrobia,2IVMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1593
ZZS2_k127_7774559_6	497964.CfE428DRAFT_4806	6.281e-123	407.0	COG0412@1|root,COG0412@2|Bacteria,46TBX@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_19	497964.CfE428DRAFT_0226	6.532e-54	197.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
ZZS2_k127_7774559_10	497964.CfE428DRAFT_2568	1.126e-94	319.0	COG2220@1|root,COG2220@2|Bacteria,46UIR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS2_k127_7774559_42	889378.Spiaf_1653	2.826e-16	81.0	2EH48@1|root,33AW7@2|Bacteria,2J921@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7774559_51	298653.Franean1_1841	5.602e-08	57.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
ZZS2_k127_7774559_3	497964.CfE428DRAFT_4707	6.071e-148	478.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
ZZS2_k127_7774559_38	1382356.JQMP01000004_gene600	4.889e-21	97.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
ZZS2_k127_7774559_48	266117.Rxyl_2552	1.292e-09	61.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	ThiS
ZZS2_k127_7774559_4	1041146.ATZB01000058_gene4180	4.901e-128	424.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,4BC0Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
ZZS2_k127_7774559_34	215803.DB30_6964	2.258e-29	120.0	COG3507@1|root,COG3507@2|Bacteria,1MWY2@1224|Proteobacteria,4391R@68525|delta/epsilon subdivisions,2X479@28221|Deltaproteobacteria,2YYED@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
ZZS2_k127_7784351_47	1403819.BATR01000130_gene4597	2.044e-47	186.0	2DTXG@1|root,33N3G@2|Bacteria,46WXU@74201|Verrucomicrobia,2IVTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
ZZS2_k127_7784351_19	1121405.dsmv_1085	7.529e-113	388.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
ZZS2_k127_7784351_32	1123073.KB899242_gene1477	1.353e-79	273.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
ZZS2_k127_7784351_16	240016.ABIZ01000001_gene3117	7.042e-121	395.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_7784351_5	497964.CfE428DRAFT_4050	7.219e-178	598.0	COG2319@1|root,COG2319@2|Bacteria,46TQT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
ZZS2_k127_7784351_8	497964.CfE428DRAFT_2767	8.35e-164	548.0	COG3064@1|root,COG3064@2|Bacteria,46TED@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7784351_11	1396141.BATP01000060_gene4643	1.251e-145	469.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,PIG-L,Ricin_B_lectin,VCBS
ZZS2_k127_7784351_30	1184267.A11Q_150	5.813e-83	293.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2WVFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
ZZS2_k127_7784351_10	483219.LILAB_30160	1.8e-153	500.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
ZZS2_k127_7784351_25	452637.Oter_2739	1.815e-85	299.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,3K7I6@414999|Opitutae	414999|Opitutae	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
ZZS2_k127_7784351_6	497964.CfE428DRAFT_5484	3.126e-175	572.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ZZS2_k127_7784351_48	1173028.ANKO01000159_gene5219	5.062e-47	183.0	COG0642@1|root,COG2205@2|Bacteria,1G3AM@1117|Cyanobacteria,1HA0Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
ZZS2_k127_7784351_22	497964.CfE428DRAFT_2172	2.313e-102	348.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
ZZS2_k127_7784351_61	1173020.Cha6605_4187	7.982e-05	55.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
ZZS2_k127_7784351_14	929562.Emtol_0684	3.518e-123	403.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_7784351_40	945713.IALB_0357	9.28e-64	226.0	COG0602@1|root,COG0602@2|Bacteria	2|Bacteria	H	queuosine metabolic process	queE	-	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
ZZS2_k127_7784351_20	1123070.KB899254_gene1284	7.225e-112	377.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
ZZS2_k127_7784351_49	500635.MITSMUL_04410	5.876e-46	177.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4H210@909932|Negativicutes	909932|Negativicutes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
ZZS2_k127_7784351_41	452637.Oter_2376	7.847e-63	220.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS2_k127_7784351_55	436114.SYO3AOP1_1751	5.493e-32	141.0	COG5000@1|root,COG5000@2|Bacteria,2G5HD@200783|Aquificae	200783|Aquificae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_7784351_18	1121918.ARWE01000001_gene1548	3.945e-118	395.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_7784351_42	497964.CfE428DRAFT_2670	5.502e-62	224.0	COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Amino_oxidase,SQS_PSY
ZZS2_k127_7784351_36	395961.Cyan7425_4972	5.986e-67	237.0	COG3394@1|root,COG3394@2|Bacteria,1G2GK@1117|Cyanobacteria	1117|Cyanobacteria	G	TIGRFAM hopanoid biosynthesis associated protein HpnK	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YdjC
ZZS2_k127_7784351_58	398767.Glov_3092	1.909e-16	84.0	COG2510@1|root,COG2510@2|Bacteria,1NDZV@1224|Proteobacteria,42V6K@68525|delta/epsilon subdivisions,2WRTX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_7784351_60	745310.G432_09175	1.794e-07	61.0	COG0775@1|root,COG0775@2|Bacteria,1PETT@1224|Proteobacteria,2TTTB@28211|Alphaproteobacteria,2K573@204457|Sphingomonadales	204457|Sphingomonadales	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
ZZS2_k127_7784351_44	1191523.MROS_1767	1.978e-56	206.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
ZZS2_k127_7784351_27	1128421.JAGA01000003_gene3247	6.138e-84	302.0	COG2304@1|root,COG2304@2|Bacteria,2NQHG@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_7784351_9	497964.CfE428DRAFT_4593	5.448e-161	525.0	COG1227@1|root,COG1227@2|Bacteria,46UKX@74201|Verrucomicrobia	74201|Verrucomicrobia	CK	CBS domain containing protein	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
ZZS2_k127_7784351_26	794903.OPIT5_02045	7.565e-85	288.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,3K7TC@414999|Opitutae	414999|Opitutae	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
ZZS2_k127_7784351_53	1379270.AUXF01000002_gene1178	7.075e-40	158.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
ZZS2_k127_7784351_2	335543.Sfum_1859	2.16e-227	726.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,42Q50@68525|delta/epsilon subdivisions,2WJN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7784351_13	497964.CfE428DRAFT_5386	7.039e-136	439.0	COG2876@1|root,COG2876@2|Bacteria,46SUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ZZS2_k127_7784351_17	251229.Chro_2414	3.574e-120	412.0	COG0745@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,3VHZD@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
ZZS2_k127_7784351_46	1232410.KI421420_gene3223	1.484e-50	183.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,42S64@68525|delta/epsilon subdivisions,2WPJC@28221|Deltaproteobacteria,43URS@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_7784351_0	497964.CfE428DRAFT_0776	1.225e-305	956.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
ZZS2_k127_7784351_12	1122963.AUHB01000001_gene306	2.084e-137	454.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_7784351_33	1210884.HG799465_gene11540	1.197e-76	265.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS2_k127_7784351_29	661478.OP10G_1015	4.975e-83	286.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS2_k127_7784351_56	1121033.AUCF01000008_gene5679	1.774e-24	109.0	COG5350@1|root,COG5350@2|Bacteria,1RB7D@1224|Proteobacteria,2U59N@28211|Alphaproteobacteria,2JT44@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
ZZS2_k127_7784351_45	309803.CTN_0776	1.12e-51	198.0	COG1172@1|root,COG1172@2|Bacteria,2GC5N@200918|Thermotogae	200918|Thermotogae	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
ZZS2_k127_7784351_1	886293.Sinac_7008	3.07e-247	770.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7784351_4	497964.CfE428DRAFT_4159	8.708e-195	614.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_7784351_43	452637.Oter_4507	1.987e-59	213.0	COG1335@1|root,COG1335@2|Bacteria,46UUK@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	isochorismatase hydrolase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
ZZS2_k127_7784351_23	497964.CfE428DRAFT_2167	2.475e-99	345.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
ZZS2_k127_7784351_52	909663.KI867151_gene3130	1.437e-41	159.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria,2MRTY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS2_k127_7784351_37	278957.ABEA03000080_gene3199	2.738e-66	232.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K93U@414999|Opitutae	414999|Opitutae	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
ZZS2_k127_7784351_51	497964.CfE428DRAFT_0567	3.308e-42	160.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
ZZS2_k127_7784351_24	1122927.KB895418_gene2644	6.019e-91	305.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
ZZS2_k127_7784351_59	289376.THEYE_A0819	1.284e-15	81.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
ZZS2_k127_7784351_57	1221537.B807_403	1.26e-23	102.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
ZZS2_k127_7784351_7	497964.CfE428DRAFT_3485	4.473e-171	550.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7784351_50	760192.Halhy_3568	2.769e-42	167.0	COG1082@1|root,COG1082@2|Bacteria,4PJ9G@976|Bacteroidetes,1IZP5@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_7784351_54	208444.JNYY01000022_gene3158	4.48e-37	148.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3Y8@85010|Pseudonocardiales	201174|Actinobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_7784351_28	1403819.BATR01000104_gene3588	4.937e-83	290.0	COG1082@1|root,COG1082@2|Bacteria,46UGG@74201|Verrucomicrobia,2IU3P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_7784351_15	362242.MUL_0911	3.527e-123	412.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,234KQ@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_7784351_34	1232410.KI421415_gene3061	1.424e-75	260.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
ZZS2_k127_7784351_31	240016.ABIZ01000001_gene97	2.2e-82	291.0	COG0654@1|root,COG0654@2|Bacteria,46VIV@74201|Verrucomicrobia,2IWBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
ZZS2_k127_7784351_21	1403819.BATR01000040_gene1208	5.147e-109	365.0	COG3424@1|root,COG3424@2|Bacteria,46U8Y@74201|Verrucomicrobia,2IURR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA
ZZS2_k127_7784351_3	240016.ABIZ01000001_gene1534	9.972e-201	653.0	COG0265@1|root,COG2912@1|root,COG0265@2|Bacteria,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	hhoB	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	TPR_9,Transglut_core2,Trypsin_2
ZZS2_k127_7784351_38	522306.CAP2UW1_1843	3.91e-65	234.0	COG3642@1|root,COG3642@2|Bacteria	2|Bacteria	T	kinase activity	inaA	-	2.7.11.1,3.6.1.27	ko:K02848,ko:K07178,ko:K19302	ko00540,ko00550,ko01100,ko03008,map00540,map00550,map01100,map03008	M00080	R05627	RC00002	ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko01011,ko03009	-	-	-	APH,DUF4032,Kdo
ZZS2_k127_7784351_39	1123508.JH636441_gene3436	6.111e-65	237.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_7784351_35	1123508.JH636441_gene3436	3.345e-70	259.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_7790388_2	1280950.HJO_17359	2.439e-39	166.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7
ZZS2_k127_7790388_5	1502852.FG94_01495	2.739e-15	89.0	COG1073@1|root,COG1073@2|Bacteria,1R67P@1224|Proteobacteria,2WCMH@28216|Betaproteobacteria,477WK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ZZS2_k127_7790388_3	497964.CfE428DRAFT_4864	1.12e-34	141.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7790388_4	575540.Isop_2194	6.056e-32	136.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
ZZS2_k127_7790388_0	756272.Plabr_4309	1.131e-128	423.0	COG2730@1|root,COG2730@2|Bacteria,2J2Q8@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
ZZS2_k127_7790388_1	525904.Tter_1998	1.097e-62	245.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CW_binding_1,Cellulase,Collagen_bind_2,DUF4038,DUF5060
ZZS2_k127_7790388_6	5888.CAK76068	3.553e-07	64.0	COG2866@1|root,KOG3641@2759|Eukaryota	2759|Eukaryota	E	protein deglutamylation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS2_k127_7790440_0	1116472.MGMO_204c00010	8.429e-133	440.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,1XFQJ@135618|Methylococcales	135618|Methylococcales	S	PFAM Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
ZZS2_k127_7790440_1	1267534.KB906755_gene4117	7.873e-114	382.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_7790440_2	700598.Niako_2166	2.287e-53	200.0	COG0859@1|root,COG0859@2|Bacteria,4NIRT@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS2_k127_7824958_11	1183438.GKIL_4354	2.556e-43	174.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_7824958_6	1267534.KB906755_gene4272	1.281e-131	433.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	AAA_19,Ank,Ank_2,Ank_3,Ank_4,Ank_5,Sigma70_r2,Sigma70_r4,Viral_helicase1
ZZS2_k127_7824958_9	452637.Oter_1885	7.833e-103	365.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_7824958_16	1379270.AUXF01000003_gene3801	0.0002146	53.0	COG2834@1|root,COG2834@2|Bacteria,1ZUJG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7824958_0	452637.Oter_1828	1.161e-281	886.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_7824958_2	234267.Acid_7947	2.954e-265	839.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_7824958_1	234267.Acid_0700	1.693e-268	848.0	COG0577@1|root,COG0577@2|Bacteria,3Y321@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_7824958_10	861299.J421_0284	6.335e-101	333.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_7824958_8	1267535.KB906767_gene632	6.312e-113	369.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_7824958_7	204669.Acid345_0366	1.916e-124	411.0	COG0845@1|root,COG0845@2|Bacteria,3Y2FV@57723|Acidobacteria,2JHN2@204432|Acidobacteriia	204432|Acidobacteriia	M	MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
ZZS2_k127_7824958_14	269799.Gmet_1190	4.84e-15	88.0	COG1538@1|root,COG1538@2|Bacteria,1NEHN@1224|Proteobacteria,43BDI@68525|delta/epsilon subdivisions,2X6S7@28221|Deltaproteobacteria,43W3Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_7824958_13	215803.DB30_6858	8.124e-17	96.0	COG3055@1|root,COG5563@1|root,COG3055@2|Bacteria,COG5563@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glyoxal oxidase N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1,Kelch_4
ZZS2_k127_7824958_4	452637.Oter_1904	3.435e-195	620.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,3K7NF@414999|Opitutae	74201|Verrucomicrobia	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_7824958_5	234267.Acid_4169	8.45e-150	487.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS2_k127_7824958_12	194439.CT1729	1.087e-26	115.0	COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1FEW7@1090|Chlorobi	1090|Chlorobi	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
ZZS2_k127_7824958_3	1403819.BATR01000007_gene203	5.82e-263	852.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,GSDH,HEAT_2,Laminin_G_3,Lipase_GDSL_2,ThuA
ZZS2_k127_7824958_15	459349.CLOAM0816	2.571e-12	70.0	COG3118@1|root,COG3118@2|Bacteria,2NPNZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the thioredoxin family	trxA	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
ZZS2_k127_7834815_4	316274.Haur_4505	1.7e-05	57.0	COG5624@1|root,COG5624@2|Bacteria,2G94N@200795|Chloroflexi,377N8@32061|Chloroflexia	200795|Chloroflexi	K	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7834815_0	671143.DAMO_0449	4.23e-83	296.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3367,DUF5122,HemolysinCabind,NPCBM
ZZS2_k127_7834815_1	234267.Acid_1337	1.995e-63	227.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
ZZS2_k127_7834815_2	765420.OSCT_3130	3.255e-47	184.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
ZZS2_k127_7844675_1	247490.KSU1_C1376	2.475e-79	277.0	COG4313@1|root,COG4313@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
ZZS2_k127_7844675_0	485917.Phep_0332	1.465e-131	446.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NGAU@976|Bacteroidetes,1IWXQ@117747|Sphingobacteriia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS2_k127_7861342_14	1396141.BATP01000029_gene2242	3.337e-12	76.0	COG1404@1|root,COG1404@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_7861342_2	1403819.BATR01000133_gene4711	6.019e-151	489.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia,2IU8C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
ZZS2_k127_7861342_8	1396418.BATQ01000092_gene5851	7.658e-46	177.0	2ES1A@1|root,33JKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7861342_1	1396141.BATP01000032_gene4431	1.503e-233	767.0	COG1595@1|root,COG3533@1|root,COG1595@2|Bacteria,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	1.3.7.14,1.3.7.15	ko:K03088,ko:K11333	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000,ko03021	-	-	-	Alginate_lyase,Fer4_NifH,Glyco_hydro_cc,Laminin_G_3,Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7861342_5	247490.KSU1_C1320	1.495e-56	227.0	COG1409@1|root,COG3204@1|root,COG3420@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,COG3420@2|Bacteria,2J2JT@203682|Planctomycetes	2|Bacteria	P	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Beta_helix,CBM_35,CBM_6,Exo_endo_phos,LTD,Laminin_G_3,Metallophos
ZZS2_k127_7861342_13	497964.CfE428DRAFT_0327	3.289e-17	98.0	COG1361@1|root,COG1404@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4733@2|Bacteria,46UDB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5122
ZZS2_k127_7861342_4	306281.AJLK01000206_gene5219	9.17e-59	214.0	COG0583@1|root,COG0583@2|Bacteria,1G8J2@1117|Cyanobacteria,1JK83@1189|Stigonemataceae	1117|Cyanobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS2_k127_7861342_3	278957.ABEA03000094_gene4806	1.194e-107	357.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,3K7TX@414999|Opitutae	414999|Opitutae	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
ZZS2_k127_7861342_12	1005048.CFU_2569	1.684e-33	135.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,474QB@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
ZZS2_k127_7861342_0	497964.CfE428DRAFT_5191	8.876e-247	771.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
ZZS2_k127_7861342_10	886293.Sinac_3177	6.607e-39	154.0	COG4112@1|root,COG4112@2|Bacteria,2IZBE@203682|Planctomycetes	203682|Planctomycetes	S	Phosphoesterase (MutT	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7861342_6	886293.Sinac_3874	2.113e-54	203.0	COG0526@1|root,COG4796@1|root,COG0526@2|Bacteria,COG4796@2|Bacteria,2J147@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_7861342_9	886293.Sinac_3874	1.3e-41	164.0	COG0526@1|root,COG4796@1|root,COG0526@2|Bacteria,COG4796@2|Bacteria,2J147@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_7861342_11	761193.Runsl_4613	2.29e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,4NTXG@976|Bacteroidetes,47R2Z@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_7861342_7	1396141.BATP01000005_gene6002	7.124e-49	179.0	COG2931@1|root,COG2931@2|Bacteria,46UDY@74201|Verrucomicrobia,2IWGN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7863191_4	313606.M23134_00848	1.55e-98	363.0	COG4733@1|root,COG4733@2|Bacteria,4PMCT@976|Bacteroidetes,47Y15@768503|Cytophagia	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_7863191_13	313606.M23134_01437	4.392e-11	78.0	COG2152@1|root,COG3210@1|root,COG3291@1|root,COG2152@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.2.2.3	ko:K01729,ko:K09942	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	CHU_C,PKD
ZZS2_k127_7863191_15	1396141.BATP01000051_gene3312	7.144e-09	70.0	COG3209@1|root,COG3266@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,MucBP,Phospholip_A2_3,YSIRK_signal
ZZS2_k127_7863191_8	272134.KB731324_gene6611	1.878e-58	233.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
ZZS2_k127_7863191_18	1123508.JH636443_gene4604	0.0001124	53.0	COG2165@1|root,COG2165@2|Bacteria,2IZ0Y@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_7863191_14	1123008.KB905695_gene2653	4.893e-10	73.0	COG3345@1|root,COG4733@1|root,COG3345@2|Bacteria,COG4733@2|Bacteria,4NHM7@976|Bacteroidetes,2FNUE@200643|Bacteroidia,22WN2@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	CBM_35
ZZS2_k127_7863191_10	1392490.JHZX01000001_gene201	1.764e-18	100.0	COG1572@1|root,COG2931@1|root,COG3211@1|root,COG3540@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3211@2|Bacteria,COG3540@2|Bacteria,4NJ5V@976|Bacteroidetes,1HY63@117743|Flavobacteriia	976|Bacteroidetes	Q	twin-arginine translocation pathway signal protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_7863191_11	452637.Oter_1389	1.962e-17	88.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_7863191_17	349521.HCH_01827	6.752e-07	61.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_7863191_5	316067.Geob_3131	1.071e-96	354.0	COG1520@1|root,COG4733@1|root,COG5306@1|root,COG1520@2|Bacteria,COG4733@2|Bacteria,COG5306@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
ZZS2_k127_7863191_16	246197.MXAN_1046	5.442e-07	64.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Kelch_4,VCBS
ZZS2_k127_7863191_9	498211.CJA_0127	6.698e-23	117.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
ZZS2_k127_7863191_3	1396141.BATP01000033_gene4254	1.949e-110	401.0	COG5434@1|root,COG5434@2|Bacteria,46TEZ@74201|Verrucomicrobia,2IWAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7863191_0	240016.ABIZ01000001_gene575	0.0	1139.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	cga	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_C,Glucodextran_N,Glyco_hydro_15
ZZS2_k127_7863191_6	448385.sce1880	1.603e-91	305.0	COG0431@1|root,COG0431@2|Bacteria,1MXQ8@1224|Proteobacteria,433WV@68525|delta/epsilon subdivisions,2X8XD@28221|Deltaproteobacteria,2YXH7@29|Myxococcales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS2_k127_7863191_1	530564.Psta_0582	2.699e-169	537.0	COG1064@1|root,COG1064@2|Bacteria,2IY4H@203682|Planctomycetes	203682|Planctomycetes	C	alcohol dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_7863191_7	395965.Msil_3585	5.495e-70	243.0	2DKVG@1|root,30GRY@2|Bacteria,1RDQT@1224|Proteobacteria,2U774@28211|Alphaproteobacteria,3NCHT@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
ZZS2_k127_7863191_2	497964.CfE428DRAFT_3780	1.426e-168	535.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,46TM8@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
ZZS2_k127_7863191_12	1267533.KB906736_gene1468	1.617e-16	80.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
ZZS2_k127_7868142_5	452637.Oter_4178	1.588e-51	190.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia,3K7SM@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7868142_4	452637.Oter_2422	2.63e-56	202.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_7868142_3	1382359.JIAL01000001_gene1019	1.019e-113	373.0	COG0008@1|root,COG0008@2|Bacteria,3Y4TS@57723|Acidobacteria,2JKAU@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ZZS2_k127_7868142_0	330214.NIDE2903	3.937e-182	584.0	COG1213@1|root,COG2513@1|root,COG1213@2|Bacteria,COG2513@2|Bacteria	2|Bacteria	G	methylisocitrate lyase activity	pepM	-	2.7.7.74,5.4.2.9	ko:K01841,ko:K07281	ko00440,ko00562,ko01100,ko01120,ko01130,map00440,map00562,map01100,map01120,map01130	-	R00661,R09669	RC00002,RC02792	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,PEP_mutase
ZZS2_k127_7868142_2	1380394.JADL01000012_gene1070	2.631e-120	398.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,2JVP8@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
ZZS2_k127_7868142_1	926550.CLDAP_13850	1.044e-136	445.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	2|Bacteria	E	PFAM aminotransferase class V	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
ZZS2_k127_7876235_30	743718.Isova_2394	0.0008562	43.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4F4WA@85017|Promicromonosporaceae	201174|Actinobacteria	C	UDP binding domain	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS2_k127_7876235_21	1396141.BATP01000060_gene4768	6.644e-15	84.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7876235_12	118163.Ple7327_4539	4.197e-72	273.0	COG0823@1|root,COG1404@1|root,COG2931@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1GJ0J@1117|Cyanobacteria,3VIZ2@52604|Pleurocapsales	1117|Cyanobacteria	QU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,SdrD_B
ZZS2_k127_7876235_26	332101.JIBU02000013_gene1351	1.125e-08	69.0	COG1361@1|root,COG1572@1|root,COG2247@1|root,COG2374@1|root,COG3386@1|root,COG4447@1|root,COG5492@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2247@2|Bacteria,COG2374@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,COG5492@2|Bacteria,1V3RT@1239|Firmicutes,25BDG@186801|Clostridia,36WE8@31979|Clostridiaceae	1239|Firmicutes	MN	Carbohydrate binding domain X2	-	-	-	-	-	-	-	-	-	-	-	-	CBM_X2,CW_binding_2,Cadherin-like,Laminin_G_3,SLH
ZZS2_k127_7876235_24	1396141.BATP01000034_gene4198	1.491e-11	78.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_7876235_5	215803.DB30_1549	1.128e-146	477.0	COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,42WGB@68525|delta/epsilon subdivisions,2WQ7V@28221|Deltaproteobacteria,2YXI7@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
ZZS2_k127_7876235_2	215803.DB30_1550	8.05e-189	604.0	COG2345@1|root,COG2345@2|Bacteria,1MXT0@1224|Proteobacteria,438Q1@68525|delta/epsilon subdivisions,2X8VS@28221|Deltaproteobacteria,2YXGQ@29|Myxococcales	28221|Deltaproteobacteria	K	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7876235_6	483219.LILAB_15195	1.339e-141	471.0	2A50E@1|root,30TNM@2|Bacteria,1PDKQ@1224|Proteobacteria,4340N@68525|delta/epsilon subdivisions,2X4G0@28221|Deltaproteobacteria,2YYY5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7876235_13	1210884.HG799474_gene15102	5.411e-65	244.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_7876235_29	1158318.ATXC01000001_gene580	0.0005314	53.0	COG2844@1|root,COG2844@2|Bacteria,2G3VT@200783|Aquificae	200783|Aquificae	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
ZZS2_k127_7876235_3	497964.CfE428DRAFT_3710	6.998e-187	591.0	COG1225@1|root,COG1225@2|Bacteria,46TJA@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_7876235_16	313603.FB2170_10111	2.296e-46	196.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
ZZS2_k127_7876235_9	1396141.BATP01000043_gene1929	1.771e-101	378.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_7876235_25	745411.B3C1_16882	4.517e-09	72.0	COG2356@1|root,COG2356@2|Bacteria	2|Bacteria	L	deoxyribonuclease I activity	bsn	GO:0005575,GO:0005576	-	ko:K07004,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Endonuclease_1,LTD
ZZS2_k127_7876235_18	1396141.BATP01000059_gene2521	2.865e-20	109.0	COG2133@1|root,COG2931@1|root,COG3055@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,4.2.2.2	ko:K00428,ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin,fn3
ZZS2_k127_7876235_23	682795.AciX8_3725	8.225e-12	81.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
ZZS2_k127_7876235_20	580332.Slit_0744	1.777e-15	88.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_7876235_22	278957.ABEA03000069_gene3974	6.823e-14	80.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_7876235_10	497964.CfE428DRAFT_3169	3.685e-91	316.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
ZZS2_k127_7876235_19	1396418.BATQ01000142_gene3277	1.159e-18	91.0	COG1055@1|root,COG1055@2|Bacteria,46S6A@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
ZZS2_k127_7876235_17	1210884.HG799463_gene10172	2.453e-32	132.0	COG0508@1|root,COG0508@2|Bacteria,2IXCU@203682|Planctomycetes	203682|Planctomycetes	C	e3 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS2_k127_7876235_1	1210884.HG799463_gene10171	1.217e-298	929.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2IYRX@203682|Planctomycetes	203682|Planctomycetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
ZZS2_k127_7876235_15	1380390.JIAT01000010_gene3534	1.836e-61	223.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
ZZS2_k127_7876235_8	1123242.JH636435_gene2135	6.215e-113	374.0	COG1028@1|root,COG1028@2|Bacteria,2J2DG@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_7876235_7	1123508.JH636441_gene3133	1.744e-120	398.0	COG0111@1|root,COG0111@2|Bacteria,2IYRW@203682|Planctomycetes	203682|Planctomycetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS2_k127_7876235_11	234267.Acid_0683	2.807e-87	303.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_7876235_4	1210884.HG799463_gene10170	7.695e-161	518.0	COG2271@1|root,COG2271@2|Bacteria,2IXXA@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_7876235_0	1123242.JH636437_gene6081	0.0	1523.0	COG2010@1|root,COG2010@2|Bacteria,2IX6S@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
ZZS2_k127_78824_6	1396141.BATP01000036_gene3853	2.626e-58	210.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS2_k127_78824_1	1396141.BATP01000036_gene3854	1.23e-136	443.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_78824_0	404380.Gbem_1067	2.872e-138	449.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_78824_5	338966.Ppro_2873	1.712e-72	258.0	COG5653@1|root,COG5653@2|Bacteria,1QUMR@1224|Proteobacteria,42QYU@68525|delta/epsilon subdivisions,2WMPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM FemAB-related protein, PEP-CTERM system-associated	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
ZZS2_k127_78824_3	382464.ABSI01000002_gene4315	4.667e-100	354.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46X8V@74201|Verrucomicrobia,2IV1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_78824_2	1396141.BATP01000059_gene2456	1.266e-111	387.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_78824_4	690850.Desaf_0734	3.298e-86	312.0	COG0438@1|root,COG0438@2|Bacteria,1PERD@1224|Proteobacteria,42VK8@68525|delta/epsilon subdivisions,2WSBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_78824_7	497964.CfE428DRAFT_4171	3.809e-23	107.0	2ETM2@1|root,33M4S@2|Bacteria,46WNN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7892592_5	497964.CfE428DRAFT_0535	3.109e-122	404.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia	74201|Verrucomicrobia	CP	NADH Ubiquinone plastoquinone (complex I)	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
ZZS2_k127_7892592_4	478741.JAFS01000002_gene664	1.656e-125	419.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,37GAQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS2_k127_7892592_9	635013.TherJR_2028	1.14e-102	352.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS2_k127_7892592_19	1267534.KB906756_gene316	4.736e-49	181.0	2AQME@1|root,31FUG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7892592_12	1123508.JH636452_gene7033	3.343e-90	303.0	COG0745@1|root,COG0745@2|Bacteria,2IYWV@203682|Planctomycetes	203682|Planctomycetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_7892592_6	1396141.BATP01000060_gene4741	1.144e-112	381.0	COG0642@1|root,COG2205@2|Bacteria,46TQY@74201|Verrucomicrobia,2IVC3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_7892592_2	240016.ABIZ01000001_gene3557	5.792e-144	467.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
ZZS2_k127_7892592_14	452637.Oter_3825	1.891e-86	293.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
ZZS2_k127_7892592_22	1396141.BATP01000040_gene2123	1.6e-09	64.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,2IUIB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
ZZS2_k127_7892592_1	1403819.BATR01000065_gene1925	1.859e-151	496.0	COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
ZZS2_k127_7892592_15	1192034.CAP_8072	2.159e-83	286.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5XK@28221|Deltaproteobacteria,2Z2YK@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
ZZS2_k127_7892592_16	1209072.ALBT01000012_gene3299	5.199e-80	287.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1FFZ6@10|Cellvibrio	1236|Gammaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021	BPD_transp_1,OppC_N
ZZS2_k127_7892592_7	886293.Sinac_3442	6.851e-110	396.0	COG0526@1|root,COG1470@1|root,COG1595@1|root,COG0526@2|Bacteria,COG1470@2|Bacteria,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	AhpC-TSA,DUF4384,NPCBM_assoc,PEGA,Sigma70_r2,Sigma70_r4_2,Thioredoxin_8
ZZS2_k127_7892592_17	44060.JODL01000031_gene1704	1.144e-76	284.0	COG5297@1|root,COG5297@2|Bacteria,2IF5E@201174|Actinobacteria	201174|Actinobacteria	G	Fn3 associated	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH
ZZS2_k127_7892592_21	1210884.HG799465_gene11380	5.505e-25	117.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_7892592_20	1396141.BATP01000056_gene3259	9.357e-42	175.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
ZZS2_k127_7892592_10	234267.Acid_2079	8.891e-100	350.0	COG1621@1|root,COG1621@2|Bacteria,3Y45X@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 32	-	-	3.2.1.26,3.2.1.80	ko:K01193,ko:K03332	ko00051,ko00052,ko00500,ko01100,map00051,map00052,map00500,map01100	-	R00801,R00802,R00879,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
ZZS2_k127_7892592_18	1128421.JAGA01000002_gene494	1.527e-52	192.0	COG0503@1|root,COG0503@2|Bacteria,2NPGX@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	PRTase_2,Pribosyltran,TRSP
ZZS2_k127_7892592_8	497964.CfE428DRAFT_4839	1.075e-109	364.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_7892592_13	379066.GAU_1612	4.58e-90	302.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
ZZS2_k127_7892592_11	35754.JNYJ01000037_gene4651	2.172e-91	308.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DH2X@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_7892592_0	33876.JNXY01000025_gene5296	1.319e-212	669.0	COG4225@1|root,COG4225@2|Bacteria,2I2TJ@201174|Actinobacteria,4DGGH@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
ZZS2_k127_7892592_3	1210884.HG799464_gene10793	3.108e-127	415.0	COG1052@1|root,COG1052@2|Bacteria,2IXB3@203682|Planctomycetes	203682|Planctomycetes	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	ko:K04496	ko04310,ko04330,ko05200,ko05220,map04310,map04330,map05200,map05220	-	-	-	ko00000,ko00001,ko04131	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS2_k127_7911360_0	1396141.BATP01000060_gene4727	9.51e-170	567.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_7911360_1	716928.AJQT01000043_gene3215	7.452e-21	104.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2U6VS@28211|Alphaproteobacteria,4BM30@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaK	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_793101_1	1217718.ALOU01000007_gene1259	1.045e-93	325.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,1KF02@119060|Burkholderiaceae	28216|Betaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
ZZS2_k127_793101_2	1500301.JQMF01000022_gene5641	7.444e-72	254.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,4B9DE@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
ZZS2_k127_793101_0	420324.KI911970_gene1564	1.151e-224	702.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
ZZS2_k127_7936363_8	700598.Niako_1749	5.13e-55	201.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
ZZS2_k127_7936363_0	1396418.BATQ01000056_gene200	0.0	1048.0	COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,46TKT@74201|Verrucomicrobia,2ITY9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
ZZS2_k127_7936363_9	862908.BMS_0882	6.728e-46	179.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,42PNE@68525|delta/epsilon subdivisions,2MTBR@213481|Bdellovibrionales,2WKCK@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	FtsJ-like methyltransferase	-	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
ZZS2_k127_7936363_2	314230.DSM3645_21082	6.415e-151	491.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_7936363_4	497964.CfE428DRAFT_2718	2.316e-113	374.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS2_k127_7936363_3	452637.Oter_0886	8.341e-135	438.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
ZZS2_k127_7936363_6	269084.syc1734_d	7.743e-68	239.0	COG1043@1|root,COG1043@2|Bacteria,1G3IU@1117|Cyanobacteria,1H2QC@1129|Synechococcus	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
ZZS2_k127_7936363_7	555079.Toce_0739	3.898e-59	217.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
ZZS2_k127_7936363_5	309801.trd_0861	1.528e-111	376.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,27XK0@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
ZZS2_k127_7936363_1	497964.CfE428DRAFT_2599	1.549e-152	496.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_7936363_10	1121396.KB892901_gene2171	3.337e-21	104.0	COG1409@1|root,COG3291@1|root,COG4733@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1QZGY@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,DUF839,Exo_endo_phos,PKD
ZZS2_k127_7953964_1	497964.CfE428DRAFT_5677	1.85e-132	431.0	COG0600@1|root,COG0600@2|Bacteria,46TTV@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ZZS2_k127_7953964_0	497964.CfE428DRAFT_5676	6.304e-151	485.0	COG0715@1|root,COG0715@2|Bacteria,46UC9@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
ZZS2_k127_7953964_2	644282.Deba_2016	2.344e-08	64.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WKB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_7968649_22	497964.CfE428DRAFT_3662	6.061e-18	88.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
ZZS2_k127_7968649_23	1379698.RBG1_1C00001G0194	7.621e-17	95.0	COG3211@1|root,COG3540@1|root,COG3211@2|Bacteria,COG3540@2|Bacteria,2NS16@2323|unclassified Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoX	-	3.1.3.1	ko:K01113,ko:K07093	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF839
ZZS2_k127_7968649_2	1123508.JH636440_gene2840	7.652e-163	531.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968649_0	378806.STAUR_2160	6.478e-183	590.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria,2YXNM@29|Myxococcales	28221|Deltaproteobacteria	O	Hsp90 protein	-	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
ZZS2_k127_7968649_13	1144275.COCOR_01284	1.334e-68	246.0	COG2909@1|root,COG2909@2|Bacteria,1RBW5@1224|Proteobacteria,42QM8@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968649_17	1382306.JNIM01000001_gene2336	8.541e-56	205.0	arCOG10178@1|root,2ZAAA@2|Bacteria	2|Bacteria	S	PFAM CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi
ZZS2_k127_7968649_18	497964.CfE428DRAFT_0033	1.194e-51	184.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
ZZS2_k127_7968649_1	452637.Oter_2476	4.97e-174	558.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,3K7NK@414999|Opitutae	414999|Opitutae	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
ZZS2_k127_7968649_16	1121428.DESHY_60035___1	1.148e-57	212.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
ZZS2_k127_7968649_10	497964.CfE428DRAFT_2138	1.968e-91	313.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia	74201|Verrucomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
ZZS2_k127_7968649_4	102129.Lepto7375DRAFT_2777	1.887e-157	507.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,1H8F2@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
ZZS2_k127_7968649_12	1123276.KB893301_gene4197	2.786e-77	274.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
ZZS2_k127_7968649_21	471852.Tcur_3381	2.716e-26	110.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
ZZS2_k127_7968649_3	452637.Oter_3975	7.904e-158	503.0	COG0451@1|root,COG0451@2|Bacteria,46SJG@74201|Verrucomicrobia,3K7RE@414999|Opitutae	74201|Verrucomicrobia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS2_k127_7968649_8	1116472.MGMO_94c00200	5.519e-121	402.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XE5W@135618|Methylococcales	1236|Gammaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	GO:0000271,GO:0003674,GO:0003824,GO:0003979,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_2287	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS2_k127_7968649_20	497964.CfE428DRAFT_5036	8.97e-44	165.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS2_k127_7968649_15	1396141.BATP01000021_gene181	4.596e-58	211.0	COG1595@1|root,COG1595@2|Bacteria,46TV8@74201|Verrucomicrobia,2IVT7@203494|Verrucomicrobiae	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968649_9	1396141.BATP01000021_gene180	6.41e-109	384.0	COG0515@1|root,COG0515@2|Bacteria	1396141.BATP01000021_gene180|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968649_6	1396418.BATQ01000136_gene3726	1.39e-147	476.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
ZZS2_k127_7968649_5	497964.CfE428DRAFT_2490	7.22e-153	503.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
ZZS2_k127_7968649_11	1156937.MFUM_940043	7.414e-78	268.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia,37GEK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
ZZS2_k127_7968649_14	497964.CfE428DRAFT_2488	7.809e-63	239.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968649_7	443143.GM18_1939	4.244e-142	466.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
ZZS2_k127_7968649_19	1403819.BATR01000061_gene1887	5.102e-45	171.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
ZZS2_k127_7968649_25	481448.Minf_2181	5.887e-07	60.0	2AK2F@1|root,31AS4@2|Bacteria,46YZ9@74201|Verrucomicrobia,37GTC@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968649_24	497964.CfE428DRAFT_3409	2.184e-12	76.0	2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7968655_3	240016.ABIZ01000001_gene1183	1.504e-170	552.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,2IU0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
ZZS2_k127_7968655_4	1403819.BATR01000164_gene5527	5.142e-131	428.0	COG3391@1|root,COG3391@2|Bacteria,46TRW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
ZZS2_k127_7968655_1	497964.CfE428DRAFT_1556	1.895e-181	578.0	COG0001@1|root,COG0001@2|Bacteria,46S67@74201|Verrucomicrobia	74201|Verrucomicrobia	H	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS2_k127_7968655_10	481448.Minf_2277	6.351e-34	135.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,37GTE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	rnhD	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
ZZS2_k127_7968655_5	1396141.BATP01000027_gene1172	1.528e-87	296.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
ZZS2_k127_7968655_7	338963.Pcar_1452	2.3e-51	186.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WP0F@28221|Deltaproteobacteria,43SHY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
ZZS2_k127_7968655_0	886293.Sinac_3221	1.351e-186	598.0	COG2721@1|root,COG2721@2|Bacteria,2IY7Y@203682|Planctomycetes	203682|Planctomycetes	G	PFAM D-galactarate dehydratase Altronate hydrolase	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ZZS2_k127_7968655_6	452637.Oter_3319	1.309e-76	264.0	COG3347@1|root,COG3347@2|Bacteria,46VF0@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
ZZS2_k127_7968655_2	595460.RRSWK_04420	5.755e-171	549.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
ZZS2_k127_7968655_9	497964.CfE428DRAFT_3096	2.89e-40	156.0	COG0250@1|root,COG0250@2|Bacteria,46SYX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
ZZS2_k127_7968655_8	292459.STH1246	8.664e-44	172.0	COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,25CD6@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	lacC	-	2.7.1.144,2.7.1.56	ko:K00882,ko:K00917	ko00051,ko00052,ko01100,map00051,map00052,map01100	-	R02071,R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ZZS2_k127_8000317_7	530564.Psta_0134	1.986e-17	83.0	COG1520@1|root,COG1520@2|Bacteria,2IXD2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
ZZS2_k127_8000317_3	452637.Oter_4174	5.743e-59	210.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_8000317_4	5888.CAK80224	1.722e-50	207.0	COG2319@1|root,KOG0271@1|root,KOG0272@1|root,KOG0263@2759|Eukaryota,KOG0271@2759|Eukaryota,KOG0272@2759|Eukaryota,3ZDFC@5878|Ciliophora	2759|Eukaryota	S	WD domain, G-beta repeat	-	-	-	ko:K12662	ko03040,map03040	M00354	-	-	ko00000,ko00001,ko00002,ko03041	-	-	-	NACHT,Pentapeptide,Pentapeptide_4,WD40
ZZS2_k127_8000317_0	452637.Oter_1389	1.482e-152	525.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_8000317_6	324602.Caur_0299	6.33e-34	149.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
ZZS2_k127_8000317_8	398767.Glov_2338	8.589e-11	75.0	COG3055@1|root,COG3055@2|Bacteria,1NZ4C@1224|Proteobacteria,430DQ@68525|delta/epsilon subdivisions,2WVRA@28221|Deltaproteobacteria	2|Bacteria	S	Peptidase C10 family	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060,PPC,Peptidase_S8,Reprolysin_5,VPEP
ZZS2_k127_8000317_5	1396141.BATP01000028_gene2285	2.972e-34	145.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
ZZS2_k127_8000317_9	1227739.Hsw_3254	7.267e-09	59.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8000317_1	243233.MCA2830	3.225e-144	473.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
ZZS2_k127_8000317_2	1454004.AW11_00497	5.782e-91	306.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
ZZS2_k127_8000811_0	497964.CfE428DRAFT_5965	9.806e-119	385.0	COG4312@1|root,COG4312@2|Bacteria,46U2I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
ZZS2_k127_8000811_1	1403819.BATR01000093_gene2876	1.224e-24	107.0	2EGCQ@1|root,33A4H@2|Bacteria,46WJB@74201|Verrucomicrobia,2IW9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8000811_2	937777.Deipe_0659	1.126e-15	88.0	COG2128@1|root,COG2128@2|Bacteria,1WJ8T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
ZZS2_k127_8008407_23	485913.Krac_6994	6.457e-08	62.0	COG3507@1|root,COG3507@2|Bacteria,2G9A8@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
ZZS2_k127_8008407_18	351160.RRC213	2.153e-24	124.0	COG3391@1|root,arCOG02544@1|root,arCOG02544@2157|Archaea,arCOG02562@2157|Archaea,2Y7T2@28890|Euryarchaeota,2NBM7@224756|Methanomicrobia	224756|Methanomicrobia	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS2_k127_8008407_1	1202532.FF52_22839	1.196e-189	672.0	COG2373@1|root,COG2373@2|Bacteria,4PCAF@976|Bacteroidetes,1IMWQ@117743|Flavobacteriia,2NVU6@237|Flavobacterium	976|Bacteroidetes	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
ZZS2_k127_8008407_22	1232410.KI421418_gene2408	2.241e-12	84.0	COG3507@1|root,COG4733@1|root,COG3507@2|Bacteria,COG4733@2|Bacteria,1RDH5@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349
ZZS2_k127_8008407_24	768706.Desor_1391	2.621e-06	64.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
ZZS2_k127_8008407_19	1396141.BATP01000056_gene3278	3.924e-22	116.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
ZZS2_k127_8008407_5	497964.CfE428DRAFT_3537	1.22e-162	523.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
ZZS2_k127_8008407_20	583355.Caka_2133	2.678e-18	91.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8008407_14	1403819.BATR01000017_gene549	2.632e-65	234.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
ZZS2_k127_8008407_13	1121438.JNJA01000007_gene1667	6.944e-77	274.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1R6YN@1224|Proteobacteria,42Q4G@68525|delta/epsilon subdivisions,2WJM9@28221|Deltaproteobacteria,2M947@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
ZZS2_k127_8008407_17	886293.Sinac_3510	4.833e-47	181.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,PKD
ZZS2_k127_8008407_8	452637.Oter_1326	1.883e-110	374.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria	2|Bacteria	S	ferrous iron binding	amrA	-	-	ko:K06990,ko:K09141,ko:K15755	ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220	M00544	R05415	RC01306	br01602,ko00000,ko00001,ko00002,ko01000,ko04812	-	-	-	AMMECR1,LigB
ZZS2_k127_8008407_3	452637.Oter_1325	1.556e-173	550.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
ZZS2_k127_8008407_21	697282.Mettu_3263	1.376e-15	89.0	COG2067@1|root,COG2067@2|Bacteria,1NQ4A@1224|Proteobacteria,1RYKE@1236|Gammaproteobacteria,1XEJE@135618|Methylococcales	135618|Methylococcales	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
ZZS2_k127_8008407_2	1396141.BATP01000028_gene2320	3.186e-177	564.0	COG0683@1|root,COG0683@2|Bacteria,46TNV@74201|Verrucomicrobia,2ITGH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_5
ZZS2_k127_8008407_4	794903.OPIT5_19455	5.057e-167	543.0	COG0559@1|root,COG0559@2|Bacteria,46U7D@74201|Verrucomicrobia,3K73C@414999|Opitutae	414999|Opitutae	P	Urea ABC transporter permease	-	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
ZZS2_k127_8008407_6	583355.Caka_2151	4.497e-119	405.0	COG4177@1|root,COG4177@2|Bacteria,46S8E@74201|Verrucomicrobia,3K7EY@414999|Opitutae	414999|Opitutae	P	Urea ABC transporter permease	-	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
ZZS2_k127_8008407_7	1396418.BATQ01000133_gene4078	8.515e-117	380.0	COG4674@1|root,COG4674@2|Bacteria,46SHS@74201|Verrucomicrobia,2ITUB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
ZZS2_k127_8008407_12	1396418.BATQ01000133_gene4079	1.163e-88	303.0	COG0410@1|root,COG0410@2|Bacteria,46TST@74201|Verrucomicrobia,2IU3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_8008407_16	215803.DB30_6310	2.88e-48	188.0	COG0829@1|root,COG0829@2|Bacteria,1NY7J@1224|Proteobacteria,42XVF@68525|delta/epsilon subdivisions,2WNBZ@28221|Deltaproteobacteria,2YUTW@29|Myxococcales	28221|Deltaproteobacteria	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
ZZS2_k127_8008407_10	404589.Anae109_4048	8.924e-105	345.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,1RGXE@1224|Proteobacteria,42QQW@68525|delta/epsilon subdivisions,2WPBR@28221|Deltaproteobacteria,2YVJY@29|Myxococcales	28221|Deltaproteobacteria	E	Urease, gamma subunit	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
ZZS2_k127_8008407_0	1144275.COCOR_07674	2.379e-295	914.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,42NUG@68525|delta/epsilon subdivisions,2WJM4@28221|Deltaproteobacteria,2YUI0@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
ZZS2_k127_8008407_15	1192034.CAP_1389	3.185e-58	210.0	COG0830@1|root,COG0830@2|Bacteria,1NIBD@1224|Proteobacteria,42Y30@68525|delta/epsilon subdivisions,2X0IY@28221|Deltaproteobacteria,2YVZ0@29|Myxococcales	28221|Deltaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
ZZS2_k127_8008407_9	1192034.CAP_1388	3.414e-109	357.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42P7Y@68525|delta/epsilon subdivisions,2WKXK@28221|Deltaproteobacteria,2YUNK@29|Myxococcales	28221|Deltaproteobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
ZZS2_k127_8008407_11	1123508.JH636443_gene4905	4.974e-104	345.0	COG3828@1|root,COG3828@2|Bacteria,2IY3G@203682|Planctomycetes	203682|Planctomycetes	C	PFAM coagulation factor 5 8 type	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_8009883_4	1123508.JH636439_gene1075	1.872e-29	123.0	COG0412@1|root,COG0412@2|Bacteria,2IYMM@203682|Planctomycetes	203682|Planctomycetes	Q	COG0412 Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
ZZS2_k127_8009883_3	794903.OPIT5_13470	1.545e-31	130.0	2AII5@1|root,31903@2|Bacteria,46YKX@74201|Verrucomicrobia,3K9T5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8009883_7	397945.Aave_1943	2.287e-05	46.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria,4ABRX@80864|Comamonadaceae	28216|Betaproteobacteria	Q	dienelactone hydrolase	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
ZZS2_k127_8009883_1	886293.Sinac_2497	5.6e-40	173.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
ZZS2_k127_8009883_6	243233.MCA0403	1.978e-06	63.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,1XGQW@135618|Methylococcales	135618|Methylococcales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_8009883_5	1123242.JH636434_gene5196	1.165e-21	109.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidase_6,CarboxypepD_reg,LysM,PD40,Peptidase_M23,Peptidase_M56,SBP_bac_10
ZZS2_k127_8009883_0	1396141.BATP01000025_gene978	3.219e-76	289.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_8009883_2	1210884.HG799465_gene11380	7.514e-39	168.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
ZZS2_k127_8019090_4	1396141.BATP01000020_gene58	3.932e-173	558.0	COG2010@1|root,COG2010@2|Bacteria,46TEX@74201|Verrucomicrobia,2ITZG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_8019090_2	1396141.BATP01000020_gene59	1.372e-243	760.0	COG4102@1|root,COG4102@2|Bacteria,46U8M@74201|Verrucomicrobia,2ITW7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_8019090_3	497964.CfE428DRAFT_4557	7.056e-183	584.0	COG2133@1|root,COG2133@2|Bacteria,46U0G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8019090_0	886293.Sinac_2448	0.0	1133.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXS5@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH
ZZS2_k127_8028177_2	452637.Oter_2277	3.809e-175	560.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DUF4038,DUF5060,DUF721
ZZS2_k127_8028177_4	583355.Caka_0017	4.064e-82	278.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,3K7MX@414999|Opitutae	414999|Opitutae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
ZZS2_k127_8028177_0	452637.Oter_3934	3.617e-310	996.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
ZZS2_k127_8028177_1	794903.OPIT5_22585	4.487e-215	677.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
ZZS2_k127_8028177_6	583355.Caka_0020	5.069e-56	201.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
ZZS2_k127_8028177_7	478741.JAFS01000002_gene342	4.982e-47	177.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia,37GGY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_8028177_5	382464.ABSI01000020_gene188	8.974e-73	262.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,2ITX9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8028177_10	452637.Oter_3929	2.366e-05	51.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8028177_3	794903.OPIT5_22615	2.019e-100	345.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
ZZS2_k127_8028177_8	278957.ABEA03000189_gene965	9.711e-33	139.0	COG2993@1|root,COG2993@2|Bacteria,46T1F@74201|Verrucomicrobia,3K82J@414999|Opitutae	414999|Opitutae	C	cytochrome c oxidase	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
ZZS2_k127_8028177_9	1403819.BATR01000112_gene3835	1.541e-30	131.0	COG2010@1|root,COG2010@2|Bacteria,46T74@74201|Verrucomicrobia,2IWN4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_8028251_3	1340493.JNIF01000004_gene17	2.723e-15	84.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_8028251_0	1123508.JH636448_gene7676	1.022e-243	776.0	COG3794@1|root,COG3794@2|Bacteria,2J4VH@203682|Planctomycetes	203682|Planctomycetes	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
ZZS2_k127_8028251_2	1210884.HG799463_gene9801	1.005e-35	153.0	COG2755@1|root,COG3345@1|root,COG5306@1|root,COG2755@2|Bacteria,COG3345@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
ZZS2_k127_8028251_1	913325.N799_13835	7.244e-52	191.0	COG4430@1|root,COG4430@2|Bacteria,1N8ME@1224|Proteobacteria,1T0U8@1236|Gammaproteobacteria,1XD1S@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
ZZS2_k127_8051817_33	313628.LNTAR_22854	3.544e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
ZZS2_k127_8051817_9	489825.LYNGBM3L_09400	2.503e-129	428.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1H9BT@1150|Oscillatoriales	1117|Cyanobacteria	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
ZZS2_k127_8051817_26	489825.LYNGBM3L_69430	1.971e-36	151.0	COG3021@1|root,COG3021@2|Bacteria,1G1V5@1117|Cyanobacteria,1HAVR@1150|Oscillatoriales	1117|Cyanobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_8051817_11	240016.ABIZ01000001_gene2782	1.104e-95	325.0	COG1028@1|root,COG1028@2|Bacteria	240016.ABIZ01000001_gene2782|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8051817_14	573413.Spirs_1858	2.756e-84	288.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_8051817_22	497964.CfE428DRAFT_6360	4.205e-54	194.0	COG0509@1|root,COG0509@2|Bacteria,46WCE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
ZZS2_k127_8051817_12	1403819.BATR01000063_gene1912	1.357e-86	290.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,46TBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19
ZZS2_k127_8051817_3	240016.ABIZ01000001_gene887	6.555e-198	622.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia,2ITX5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alcohol dehydrogenase GroES-like domain	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_8051817_18	497964.CfE428DRAFT_4082	1.59e-79	275.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3472,DUF5077,Gram_pos_anchor,Reprolysin_4
ZZS2_k127_8051817_23	1123242.JH636434_gene3250	2.243e-53	198.0	COG2860@1|root,COG2860@2|Bacteria,2J34I@203682|Planctomycetes	203682|Planctomycetes	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
ZZS2_k127_8051817_4	521674.Plim_2077	6.264e-193	608.0	COG0156@1|root,COG0156@2|Bacteria,2IX0H@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_8051817_19	521674.Plim_3796	4.487e-74	258.0	COG2133@1|root,COG2133@2|Bacteria,2J52Q@203682|Planctomycetes	203682|Planctomycetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_8051817_13	1121428.DESHY_70012___1	6.292e-85	287.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
ZZS2_k127_8051817_31	1519464.HY22_12795	2.004e-20	93.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
ZZS2_k127_8051817_7	240016.ABIZ01000001_gene771	5.882e-140	454.0	28IED@1|root,2Z8GE@2|Bacteria,46VP7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
ZZS2_k127_8051817_21	1396141.BATP01000007_gene5566	2.589e-67	237.0	COG0767@1|root,COG0767@2|Bacteria,46SXR@74201|Verrucomicrobia,2ITY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
ZZS2_k127_8051817_16	517418.Ctha_0314	1.325e-83	284.0	COG1127@1|root,COG1127@2|Bacteria,1FEH4@1090|Chlorobi	1090|Chlorobi	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS2_k127_8051817_38	1123073.KB899241_gene2049	6.061e-09	67.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1X79T@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS2_k127_8051817_17	452637.Oter_2116	1.011e-82	286.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8051817_41	1300345.LF41_2927	0.0004688	46.0	2DSC2@1|root,33FFW@2|Bacteria,1QJUP@1224|Proteobacteria,1THW7@1236|Gammaproteobacteria,1X8XP@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
ZZS2_k127_8051817_6	497964.CfE428DRAFT_0079	9.481e-162	522.0	COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS2_k127_8051817_20	1267535.KB906767_gene4492	2.956e-70	245.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria,2JIGR@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
ZZS2_k127_8051817_24	1121430.JMLG01000010_gene208	3.511e-52	197.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
ZZS2_k127_8051817_2	344747.PM8797T_10954	7.208e-206	649.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_8051817_0	1210884.HG799469_gene14157	7.578e-282	882.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
ZZS2_k127_8051817_30	1089553.Tph_c27210	2.72e-24	106.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,42H9A@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM regulatory protein GntR HTH	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
ZZS2_k127_8051817_25	555088.DealDRAFT_2759	7.768e-50	192.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,25KAP@186801|Clostridia,42KJ1@68298|Syntrophomonadaceae	186801|Clostridia	P	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_8051817_32	1233950.IW22_05690	7.663e-19	102.0	COG3292@1|root,COG5184@1|root,COG3292@2|Bacteria,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,1IIHQ@117743|Flavobacteriia,3ZNMC@59732|Chryseobacterium	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
ZZS2_k127_8051817_37	478741.JAFS01000002_gene512	5.511e-09	66.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia,37GVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ZZS2_k127_8051817_28	497964.CfE428DRAFT_4379	8.825e-28	117.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ZZS2_k127_8051817_29	944479.JQLX01000016_gene325	8.213e-25	110.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria,2M7BC@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS2_k127_8051817_1	497964.CfE428DRAFT_0027	3.061e-232	734.0	COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
ZZS2_k127_8051817_36	452637.Oter_0986	1.484e-09	70.0	2AXAG@1|root,31P9J@2|Bacteria,46XVM@74201|Verrucomicrobia,3K8EC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8051817_5	1303518.CCALI_02577	4.398e-184	582.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
ZZS2_k127_8051817_8	1131269.AQVV01000050_gene418	8.375e-138	442.0	COG2107@1|root,COG2107@2|Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS2_k127_8051817_10	82654.Pse7367_0703	9.317e-98	332.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_8051817_35	1185876.BN8_01058	1.072e-09	73.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
ZZS2_k127_8051817_39	448385.sce1143	1.681e-08	69.0	COG3210@1|root,COG3210@2|Bacteria,1QW1H@1224|Proteobacteria	1224|Proteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8051817_34	1336803.PHEL49_1867	2.056e-10	75.0	COG2312@1|root,COG3537@1|root,COG4935@1|root,COG5337@1|root,COG2312@2|Bacteria,COG3537@2|Bacteria,COG4935@2|Bacteria,COG5337@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,3VX3A@52959|Polaribacter	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
ZZS2_k127_8051817_40	926556.Echvi_2701	1.422e-07	65.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8051817_27	926550.CLDAP_29960	4.221e-28	133.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD
ZZS2_k127_8051817_15	1396141.BATP01000034_gene4198	4.928e-84	311.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
ZZS2_k127_8096173_20	56780.SYN_01127	1.157e-21	107.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8096173_17	1380391.JIAS01000005_gene2424	9.572e-39	158.0	28Q55@1|root,2ZCN6@2|Bacteria,1P7CW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8096173_19	1192034.CAP_3217	9.068e-24	111.0	COG5036@1|root,COG5036@2|Bacteria,1RG06@1224|Proteobacteria,42RP7@68525|delta/epsilon subdivisions,2WNHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
ZZS2_k127_8096173_8	1174528.JH992898_gene2276	4.951e-92	313.0	COG1409@1|root,COG1409@2|Bacteria,1G4KM@1117|Cyanobacteria	1117|Cyanobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS2_k127_8096173_0	240016.ABIZ01000001_gene1604	3.339e-246	773.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
ZZS2_k127_8096173_5	349741.Amuc_2115	1.984e-134	445.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Seryl-tRNA synthetase N-terminal domain	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
ZZS2_k127_8096173_6	404589.Anae109_0139	1.668e-131	437.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
ZZS2_k127_8096173_13	497964.CfE428DRAFT_2117	3.575e-49	192.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
ZZS2_k127_8096173_3	582899.Hden_0371	2.461e-218	699.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,3N69J@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
ZZS2_k127_8096173_22	1123368.AUIS01000015_gene2656	1.185e-06	57.0	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,2ND92@225057|Acidithiobacillales	225057|Acidithiobacillales	T	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
ZZS2_k127_8096173_1	497964.CfE428DRAFT_5133	1.346e-239	753.0	COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
ZZS2_k127_8096173_24	1168065.DOK_05128	9.839e-06	52.0	2DPY2@1|root,333WA@2|Bacteria,1NDT4@1224|Proteobacteria,1SIB1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AP2
ZZS2_k127_8096173_15	643648.Slip_2049	1.145e-45	175.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,42JZF@68298|Syntrophomonadaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
ZZS2_k127_8096173_21	153721.MYP_3454	2.276e-08	65.0	COG2273@1|root,COG3291@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,COG5295@2|Bacteria,4NV3D@976|Bacteroidetes,47X3T@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
ZZS2_k127_8096173_23	547163.BN979_00555	2.304e-06	59.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,23AQX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
ZZS2_k127_8096173_4	886293.Sinac_5129	2.324e-213	674.0	COG4948@1|root,COG4948@2|Bacteria,2IXK2@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
ZZS2_k127_8096173_18	497964.CfE428DRAFT_2566	9.319e-31	129.0	COG2967@1|root,COG2967@2|Bacteria,46T44@74201|Verrucomicrobia	74201|Verrucomicrobia	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
ZZS2_k127_8096173_7	1396418.BATQ01000113_gene4631	9.073e-121	399.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
ZZS2_k127_8096173_12	521674.Plim_0365	9.437e-55	206.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
ZZS2_k127_8096173_10	1009370.ALO_01205	4.959e-75	266.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4H2TU@909932|Negativicutes	1239|Firmicutes	M	Monogalactosyldiacylglycerol synthase, C-terminal domain protein	ypfP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
ZZS2_k127_8096173_2	379066.GAU_0696	5.809e-237	747.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1ZU8B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_CBB3
ZZS2_k127_8096173_16	314230.DSM3645_20712	3.292e-45	172.0	COG0723@1|root,COG0723@2|Bacteria,2J13H@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
ZZS2_k127_8096173_9	497964.CfE428DRAFT_0875	2.161e-77	272.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
ZZS2_k127_8096173_14	1128421.JAGA01000004_gene2494	4.387e-47	174.0	COG0315@1|root,COG0315@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
ZZS2_k127_8096173_11	1396418.BATQ01000133_gene4028	1.462e-58	207.0	COG0521@1|root,COG0521@2|Bacteria,46SVJ@74201|Verrucomicrobia,2IUE2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
ZZS2_k127_8109969_3	43989.cce_2798	5.166e-40	154.0	COG4671@1|root,COG4671@2|Bacteria,1G0X1@1117|Cyanobacteria,3KGIG@43988|Cyanothece	1117|Cyanobacteria	S	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	iJN678.sll1722	Glyco_tran_28_C
ZZS2_k127_8109969_0	745310.G432_09085	9.017e-162	523.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2K0Q2@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_8109969_2	497964.CfE428DRAFT_4864	4.922e-62	222.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8109969_1	886293.Sinac_6489	1.607e-118	410.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_8119045_0	1178540.BA70_11445	4.244e-35	137.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,1ZHCV@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ydeP1	-	-	-	-	-	-	-	-	-	-	-	HxlR
ZZS2_k127_8119045_4	861299.J421_1753	1.074e-19	91.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
ZZS2_k127_8119045_5	38833.XP_003062474.1	1.549e-10	74.0	2E3BA@1|root,2SAF2@2759|Eukaryota	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
ZZS2_k127_8119045_1	865937.Gilli_1969	1.98e-23	116.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
ZZS2_k127_8119045_3	649831.L083_3819	2.297e-20	106.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8119045_2	326427.Cagg_3284	1.602e-20	102.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
ZZS2_k127_8120505_1	886293.Sinac_5782	1.099e-24	122.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DUF11,NPCBM_assoc
ZZS2_k127_8120505_0	349741.Amuc_0681	1.013e-160	519.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,2ITID@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mur ligase family, catalytic domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_8155560_8	667014.Thein_1214	1.721e-144	469.0	COG0151@1|root,COG0151@2|Bacteria,2GGTX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
ZZS2_k127_8155560_21	452637.Oter_2781	1.412e-13	73.0	COG1722@1|root,COG1722@2|Bacteria,46TB2@74201|Verrucomicrobia,3K8ES@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
ZZS2_k127_8155560_2	1382359.JIAL01000001_gene1947	1.541e-232	742.0	COG1154@1|root,COG1154@2|Bacteria,3Y327@57723|Acidobacteria,2JIPM@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
ZZS2_k127_8155560_10	1396141.BATP01000061_gene4541	1.853e-127	422.0	28N64@1|root,2ZBFG@2|Bacteria,46Z9S@74201|Verrucomicrobia,2IWQS@203494|Verrucomicrobiae	2|Bacteria	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
ZZS2_k127_8155560_0	266117.Rxyl_0146	1.051e-286	897.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4CQ1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
ZZS2_k127_8155560_9	313628.LNTAR_20638	1.114e-135	443.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
ZZS2_k127_8155560_7	1254432.SCE1572_47340	2.318e-159	512.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
ZZS2_k127_8155560_14	1210884.HG799474_gene15102	8.604e-62	234.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_8155560_16	497964.CfE428DRAFT_0998	3.108e-52	190.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
ZZS2_k127_8155560_4	1278073.MYSTI_00528	6.526e-169	543.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YWP2@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
ZZS2_k127_8155560_20	1403819.BATR01000164_gene5588	2.009e-18	88.0	2EMGZ@1|root,33F5K@2|Bacteria,46TB4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8155560_18	706587.Desti_3811	4.096e-24	109.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3,FR47
ZZS2_k127_8155560_19	1267005.KB911255_gene3024	4.069e-22	107.0	2C50M@1|root,32YGT@2|Bacteria,1NK10@1224|Proteobacteria,2UY4Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8155560_1	1396141.BATP01000060_gene4761	3.211e-286	936.0	COG2010@1|root,COG2133@1|root,COG2755@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,46TXK@74201|Verrucomicrobia,2IV2Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8155560_3	794903.OPIT5_28170	2.196e-205	652.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
ZZS2_k127_8155560_13	1123276.KB893270_gene4724	2.063e-86	294.0	COG1409@1|root,COG1409@2|Bacteria,4NRDF@976|Bacteroidetes,47VTX@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K21814	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	Metallophos
ZZS2_k127_8155560_6	1408254.T458_04825	9.323e-163	524.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,26T95@186822|Paenibacillaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
ZZS2_k127_8155560_12	497964.CfE428DRAFT_2712	1.156e-89	299.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ZZS2_k127_8155560_11	1396418.BATQ01000025_gene5262	8.158e-114	379.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS2_k127_8155560_5	886293.Sinac_7036	1.629e-163	523.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8155560_17	521674.Plim_0986	7.772e-44	171.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_8155560_15	886293.Sinac_3224	3.283e-60	235.0	COG0515@1|root,COG0515@2|Bacteria,2IYF2@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_8187737_8	946483.Cenrod_2340	1.476e-92	318.0	COG3039@1|root,COG3039@2|Bacteria,1R64B@1224|Proteobacteria,2W09R@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
ZZS2_k127_8187737_4	861299.J421_4338	3.251e-158	525.0	COG0457@1|root,COG0457@2|Bacteria,1ZU8U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
ZZS2_k127_8187737_17	1379270.AUXF01000004_gene3289	1.263e-40	170.0	COG2010@1|root,COG2010@2|Bacteria,1ZUYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_8187737_28	452637.Oter_2454	1.179e-16	81.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ZZS2_k127_8187737_7	760192.Halhy_3824	6.756e-103	364.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
ZZS2_k127_8187737_30	1303518.CCALI_01975	4.872e-12	75.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
ZZS2_k127_8187737_32	1122925.KB895378_gene2567	1.127e-11	78.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_8187737_21	1396141.BATP01000057_gene3033	7.825e-30	137.0	COG4632@1|root,COG4632@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
ZZS2_k127_8187737_35	794903.OPIT5_14770	2.854e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
ZZS2_k127_8187737_11	1210884.HG799474_gene15102	5.71e-59	224.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_8187737_19	497964.CfE428DRAFT_3535	3.878e-33	131.0	COG4842@1|root,COG4842@2|Bacteria,46VM0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
ZZS2_k127_8187737_23	1396418.BATQ01000117_gene4541	5.395e-24	109.0	2ET52@1|root,33KP5@2|Bacteria,46VY7@74201|Verrucomicrobia,2IVXP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8187737_37	240016.ABIZ01000001_gene2639	2.281e-05	51.0	2DD5J@1|root,2ZGMA@2|Bacteria,46WYE@74201|Verrucomicrobia,2IWBI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8187737_0	497964.CfE428DRAFT_3532	0.0	1199.0	COG1674@1|root,COG1674@2|Bacteria,46V0I@74201|Verrucomicrobia	74201|Verrucomicrobia	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
ZZS2_k127_8187737_20	1396141.BATP01000057_gene3033	1.979e-31	143.0	COG4632@1|root,COG4632@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
ZZS2_k127_8187737_33	1122925.KB895378_gene2567	2.481e-11	77.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_8187737_9	309807.SRU_2450	1.563e-83	301.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1FIWB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
ZZS2_k127_8187737_38	1121087.AUCK01000027_gene224	8.467e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
ZZS2_k127_8187737_36	497964.CfE428DRAFT_5892	3.593e-08	61.0	COG4968@1|root,COG4968@2|Bacteria,46Z8X@74201|Verrucomicrobia	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	lspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS2_k127_8187737_10	452637.Oter_1518	4.791e-80	283.0	2BYUR@1|root,32TV8@2|Bacteria,46V5C@74201|Verrucomicrobia,3K7PA@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8187737_22	62928.azo0278	1.576e-24	121.0	2EFNF@1|root,339EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8187737_1	886293.Sinac_1739	3.4e-322	1022.0	COG2010@1|root,COG2010@2|Bacteria,2IXBU@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_8187737_26	794903.OPIT5_25660	3.21e-23	109.0	COG4968@1|root,COG4968@2|Bacteria,46VVB@74201|Verrucomicrobia,3K9MA@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_8187737_34	497964.CfE428DRAFT_4779	1.875e-10	64.0	2DVX4@1|root,33XIH@2|Bacteria,46VH6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8187737_14	1123508.JH636443_gene5014	1.359e-51	209.0	COG0457@1|root,COG0457@2|Bacteria	1123508.JH636443_gene5014|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8187737_5	1396141.BATP01000057_gene2930	3.808e-156	529.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
ZZS2_k127_8187737_12	497964.CfE428DRAFT_6571	4.922e-58	208.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_8187737_6	1396141.BATP01000021_gene161	1.347e-120	394.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,2ITX7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
ZZS2_k127_8187737_25	1403819.BATR01000178_gene5965	1.789e-23	101.0	COG0695@1|root,COG0695@2|Bacteria,46TC3@74201|Verrucomicrobia,2IUWQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
ZZS2_k127_8187737_18	530564.Psta_0575	1.245e-39	151.0	COG0662@1|root,COG0662@2|Bacteria,2J4Q9@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_8187737_24	865937.Gilli_1966	1.249e-23	119.0	COG1749@1|root,COG5295@1|root,COG1749@2|Bacteria,COG5295@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
ZZS2_k127_8187737_3	583355.Caka_0091	6.301e-178	614.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,GSDH,Laminin_G_3
ZZS2_k127_8187737_27	1121430.JMLG01000033_gene1333	1.294e-19	91.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,2632X@186807|Peptococcaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
ZZS2_k127_8187737_15	497964.CfE428DRAFT_0487	7.408e-51	187.0	COG0088@1|root,COG0088@2|Bacteria,46SWJ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
ZZS2_k127_8187737_13	1121382.JQKG01000018_gene1155	7.119e-57	207.0	COG0087@1|root,COG0087@2|Bacteria,1WI2F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
ZZS2_k127_8187737_16	497964.CfE428DRAFT_0485	3.007e-49	177.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
ZZS2_k127_8187737_2	1118060.CAGZ01000015_gene1763	1.015e-250	792.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CU9M@84998|Coriobacteriia	84998|Coriobacteriia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_8202698_3	395495.Lcho_2166	3.105e-15	77.0	COG2146@1|root,COG2146@2|Bacteria,1N82Y@1224|Proteobacteria,2VX8W@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
ZZS2_k127_8202698_2	862908.BMS_2510	1.857e-140	458.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,42PD9@68525|delta/epsilon subdivisions,2MTG9@213481|Bdellovibrionales,2WKRV@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
ZZS2_k127_8202698_0	452637.Oter_3274	9.091e-297	927.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,46YF0@74201|Verrucomicrobia,3K9FR@414999|Opitutae	414999|Opitutae	G	Sucrose-6F-phosphate phosphohydrolase	-	-	3.1.3.79	ko:K13086	-	-	R08982	RC00017	ko00000,ko01000	-	-	-	S6PP
ZZS2_k127_8202698_1	1396418.BATQ01000001_gene1267	1.297e-169	548.0	COG0438@1|root,COG0438@2|Bacteria,46T7Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	2.4.1.246	ko:K13058	-	-	R08947	RC00005,RC00028	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_824070_7	240016.ABIZ01000001_gene4928	4e-17	84.0	COG1595@1|root,COG1595@2|Bacteria,46UHS@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_824070_3	330214.NIDE2581	6.486e-89	331.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_824070_5	497964.CfE428DRAFT_6196	1.479e-38	153.0	COG2319@1|root,COG2319@2|Bacteria,46THG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4034)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4034
ZZS2_k127_824070_8	487521.OCU_45090	9.973e-10	74.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,CHAT,Tox-URI2
ZZS2_k127_824070_1	1120963.KB894499_gene422	4.841e-205	712.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_824070_9	1121396.KB892900_gene2129	1.553e-07	64.0	COG1657@1|root,COG2374@1|root,COG2931@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG5306@1|root,COG1657@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5306@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
ZZS2_k127_824070_6	118173.KB235914_gene2745	2.8e-36	158.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
ZZS2_k127_824070_0	240016.ABIZ01000001_gene2155	8.057e-291	917.0	COG0557@1|root,COG0557@2|Bacteria,46U8T@74201|Verrucomicrobia,2ITHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
ZZS2_k127_824070_2	1303518.CCALI_00184	1.621e-165	545.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	galA	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_4_9,CBM_6,DUF1565
ZZS2_k127_824070_4	1303518.CCALI_00782	5.718e-75	270.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
ZZS2_k127_8241128_18	1449049.JONW01000005_gene1182	4.014e-59	205.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,2TT7K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	formate C-acetyltransferase glycine radical	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
ZZS2_k127_8241128_14	1449049.JONW01000005_gene1181	1.875e-97	326.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2TV8Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
ZZS2_k127_8241128_7	1449049.JONW01000005_gene1183	1.272e-139	456.0	COG2271@1|root,COG2271@2|Bacteria,1RGKJ@1224|Proteobacteria,2TV2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_8241128_2	497964.CfE428DRAFT_1135	8.093e-221	691.0	COG2704@1|root,COG2704@2|Bacteria	2|Bacteria	S	C4-dicarboxylate transmembrane transporter activity	dcuB	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
ZZS2_k127_8241128_1	497964.CfE428DRAFT_1136	2.075e-309	957.0	COG1027@1|root,COG1027@2|Bacteria	2|Bacteria	E	Aspartate ammonia-lyase	aspA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222	FumaraseC_C,Lyase_1
ZZS2_k127_8241128_10	762376.AXYL_06494	3.807e-120	396.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,3T3HM@506|Alcaligenaceae	28216|Betaproteobacteria	EJ	Belongs to the asparaginase 1 family	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
ZZS2_k127_8241128_19	452637.Oter_1620	6.651e-54	193.0	COG0614@1|root,COG0614@2|Bacteria,46W5F@74201|Verrucomicrobia,3K83S@414999|Opitutae	414999|Opitutae	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
ZZS2_k127_8241128_3	1216976.AX27061_1633	1.896e-192	615.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2VMWJ@28216|Betaproteobacteria,3T5UW@506|Alcaligenaceae	28216|Betaproteobacteria	U	Aspartate alanine antiporter family protein 1	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
ZZS2_k127_8241128_4	583355.Caka_2989	1.065e-154	496.0	COG2066@1|root,COG2066@2|Bacteria,46SKT@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
ZZS2_k127_8241128_5	1123070.KB899248_gene154	5.258e-153	499.0	COG2911@1|root,COG2911@2|Bacteria,46UAP@74201|Verrucomicrobia,2IVR8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8241128_15	1304885.AUEY01000002_gene359	7.362e-76	271.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MJRC@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_8241128_0	335543.Sfum_1457	0.0	1074.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS2_k127_8241128_9	204669.Acid345_4072	4.285e-129	429.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
ZZS2_k127_8241128_8	1403819.BATR01000067_gene2010	7.786e-135	435.0	COG2326@1|root,COG2326@2|Bacteria,46UWN@74201|Verrucomicrobia,2IVFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
ZZS2_k127_8241128_24	583355.Caka_1538	1.319e-14	81.0	2FGWI@1|root,348RU@2|Bacteria,46W9R@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
ZZS2_k127_8241128_21	1297742.A176_06689	4.164e-46	178.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,439F3@68525|delta/epsilon subdivisions,2X4QF@28221|Deltaproteobacteria,2YZE7@29|Myxococcales	28221|Deltaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS2_k127_8241128_13	388051.AUFE01000026_gene5201	3.076e-98	334.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2WFIJ@28216|Betaproteobacteria,1KFYY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS2_k127_8241128_17	458817.Shal_2606	8.162e-75	271.0	COG3137@1|root,COG3137@2|Bacteria,1RCKQ@1224|Proteobacteria,1S0GK@1236|Gammaproteobacteria,2QA2B@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
ZZS2_k127_8241128_20	583355.Caka_2641	2.571e-49	194.0	2C6BE@1|root,32XBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8241128_6	1304885.AUEY01000019_gene1169	1.988e-147	492.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS2_k127_8241128_11	1304885.AUEY01000019_gene1167	1.656e-111	372.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
ZZS2_k127_8241128_22	640511.BC1002_5549	8.429e-39	162.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
ZZS2_k127_8241128_16	269799.Gmet_1198	1e-75	266.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,43T3T@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
ZZS2_k127_8241128_12	234267.Acid_4498	7.683e-101	340.0	29MQ2@1|root,308MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_834566_0	497964.CfE428DRAFT_4339	0.0	1079.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Condensation,PP-binding,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
ZZS2_k127_8367232_3	765420.OSCT_3130	1.963e-74	262.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
ZZS2_k127_8367232_1	1123508.JH636449_gene7415	2.691e-154	501.0	COG0277@1|root,COG0277@2|Bacteria,2J3IG@203682|Planctomycetes	203682|Planctomycetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
ZZS2_k127_8367232_5	497964.CfE428DRAFT_5842	1.633e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,46W91@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_8367232_2	1163617.SCD_n02152	5.661e-106	349.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
ZZS2_k127_8367232_6	32042.PstZobell_20685	4.255e-31	138.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1SW2W@1236|Gammaproteobacteria,1YZRG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	MU	Cobalt-zinc-cadmium resistance protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
ZZS2_k127_8367232_0	404589.Anae109_4094	0.0	1191.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
ZZS2_k127_8367232_4	768671.ThimaDRAFT_4573	5.102e-74	269.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,1T9ZT@1236|Gammaproteobacteria,1WYMB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
ZZS2_k127_8369416_0	929703.KE386491_gene2821	1.828e-241	760.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes,47KCN@768503|Cytophagia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
ZZS2_k127_8369416_1	1123242.JH636434_gene5267	1.517e-238	749.0	COG3119@1|root,COG3119@2|Bacteria,2IXIB@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS2_k127_8369416_4	886293.Sinac_7535	4.306e-112	376.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	2|Bacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
ZZS2_k127_8369416_9	497964.CfE428DRAFT_1024	2.371e-27	115.0	2EBIG@1|root,335IZ@2|Bacteria,46WF8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8369416_3	1123242.JH636435_gene1594	4.212e-158	510.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_8369416_8	443143.GM18_1309	1.244e-30	130.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
ZZS2_k127_8369416_2	756499.Desde_1902	5.373e-162	527.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
ZZS2_k127_8369416_5	269799.Gmet_3221	1.225e-86	301.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_8369416_7	404589.Anae109_2317	2.346e-35	139.0	COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,43BGF@68525|delta/epsilon subdivisions,2X6UQ@28221|Deltaproteobacteria,2Z0CD@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
ZZS2_k127_8369416_10	497964.CfE428DRAFT_2131	8.239e-23	107.0	29NX7@1|root,309VB@2|Bacteria,46WPG@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8369416_6	382464.ABSI01000010_gene3387	1.418e-46	187.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,2IU67@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
ZZS2_k127_837261_10	1123242.JH636434_gene4140	9.611e-168	529.0	COG0057@1|root,COG0057@2|Bacteria,2IX66@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS2_k127_837261_11	518766.Rmar_1421	1.779e-165	532.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ZZS2_k127_837261_12	518766.Rmar_1420	1.92e-132	434.0	COG1228@1|root,COG1228@2|Bacteria,4P0AG@976|Bacteroidetes,1FJ21@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_837261_25	867903.ThesuDRAFT_00317	4.893e-32	134.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WCMZ@538999|Clostridiales incertae sedis	186801|Clostridia	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
ZZS2_k127_837261_20	1121861.KB899921_gene3002	9.67e-58	210.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,2JRPW@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
ZZS2_k127_837261_24	1380394.JADL01000016_gene375	2.248e-48	181.0	COG1309@1|root,COG1309@2|Bacteria,1MUE2@1224|Proteobacteria,2TT72@28211|Alphaproteobacteria,2JU6V@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_837261_15	1396418.BATQ01000186_gene2165	6.598e-91	310.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,2IU0G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 3	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_837261_21	382464.ABSI01000011_gene2968	3.038e-55	217.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_837261_27	105559.Nwat_1969	8.231e-24	118.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYUH@1236|Gammaproteobacteria,1X2A1@135613|Chromatiales	135613|Chromatiales	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS2_k127_837261_30	376686.Fjoh_3324	4.039e-11	73.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
ZZS2_k127_837261_5	1396141.BATP01000060_gene4727	2.412e-212	702.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_837261_31	1267580.AF6_0236	4.233e-06	58.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4HQUX@91061|Bacilli	91061|Bacilli	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
ZZS2_k127_837261_23	349741.Amuc_1517	1.088e-48	181.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_837261_29	530564.Psta_0781	2.337e-17	90.0	COG1309@1|root,COG1309@2|Bacteria,2J1M7@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_837261_19	1238182.C882_0258	8.644e-59	218.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
ZZS2_k127_837261_1	1123392.AQWL01000002_gene1978	2.4e-268	861.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_837261_6	1396418.BATQ01000049_gene426	5.465e-182	580.0	28IU8@1|root,2Z8T0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_837261_4	1396418.BATQ01000049_gene427	5.617e-228	715.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
ZZS2_k127_837261_9	1403819.BATR01000093_gene2833	2.824e-175	560.0	COG0160@1|root,COG0160@2|Bacteria	2|Bacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36	ko:K00821,ko:K03918,ko:K07250,ko:K13524	ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727	M00016,M00027,M00028,M00845	R00457,R00908,R01648,R02283,R04188,R04475	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
ZZS2_k127_837261_17	448385.sce2804	3.392e-87	304.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
ZZS2_k127_837261_0	448385.sce2805	0.0	1265.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_837261_18	264731.PRU_1664	8.146e-79	288.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,2FR1I@200643|Bacteroidia	976|Bacteroidetes	O	ATPase, AAA family	-	-	-	-	-	-	-	-	-	-	-	-	AAA
ZZS2_k127_837261_16	497964.CfE428DRAFT_3859	1.834e-87	302.0	COG0697@1|root,COG0697@2|Bacteria,46T3I@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_837261_2	215803.DB30_4063	7.899e-238	755.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
ZZS2_k127_837261_14	1131269.AQVV01000028_gene28	4.27e-112	404.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
ZZS2_k127_837261_8	497964.CfE428DRAFT_0790	6.586e-177	564.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
ZZS2_k127_837261_3	497964.CfE428DRAFT_3344	4.825e-230	740.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
ZZS2_k127_837261_26	1396141.BATP01000038_gene1194	1.305e-30	130.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS2_k127_837261_7	794903.OPIT5_28445	1.835e-177	565.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS2_k127_837261_22	1123253.AUBD01000011_gene2047	1.266e-50	187.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,1S3TJ@1236|Gammaproteobacteria,1X6DY@135614|Xanthomonadales	135614|Xanthomonadales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_837261_13	251221.35214536	9.455e-121	414.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1G4UJ@1117|Cyanobacteria	1117|Cyanobacteria	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
ZZS2_k127_8397154_11	1122609.AUGT01000002_gene3860	5.328e-07	63.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria,2GJEW@201174|Actinobacteria,4DPZQ@85009|Propionibacteriales	201174|Actinobacteria	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M4,Peptidase_M4_C
ZZS2_k127_8397154_9	686340.Metal_2132	7.237e-29	135.0	COG2373@1|root,COG3209@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,1QV7E@1224|Proteobacteria,1T3HZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	TIGRFAM Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8397154_0	886293.Sinac_5436	3.775e-180	576.0	COG1057@1|root,COG1057@2|Bacteria,2IYD8@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8397154_8	497964.CfE428DRAFT_0221	1.324e-34	140.0	2EKW2@1|root,33EJK@2|Bacteria,46VZV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8397154_6	1403819.BATR01000031_gene1028	5.246e-55	202.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
ZZS2_k127_8397154_1	1403819.BATR01000162_gene5307	9.621e-161	513.0	COG4260@1|root,COG4260@2|Bacteria,46UVR@74201|Verrucomicrobia,2IV4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17
ZZS2_k127_8397154_2	497964.CfE428DRAFT_2630	3.022e-153	491.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8397154_5	1131269.AQVV01000001_gene1323	5.769e-69	250.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8397154_4	497964.CfE428DRAFT_5470	3.045e-99	340.0	COG2204@1|root,COG2204@2|Bacteria,46VVS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_8397154_7	452637.Oter_4555	1.141e-44	171.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8397154_3	349161.Dred_1021	1.732e-103	349.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
ZZS2_k127_8397154_10	452637.Oter_0712	3.854e-28	119.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
ZZS2_k127_8414547_0	671143.DAMO_2856	4.737e-318	1013.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
ZZS2_k127_8422166_1	1254432.SCE1572_24665	3.662e-95	336.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	dex	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Alginate_lyase2,Big_2,CBM_2,CBM_3,CBM_5_12_2,CBM_6,F5_F8_type_C,Glyco_hydro_66,SH3_3,SLH,VWA,fn3
ZZS2_k127_8422166_5	1242864.D187_003580	2.597e-55	219.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
ZZS2_k127_8422166_8	314230.DSM3645_26699	2.691e-13	84.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8422166_6	404589.Anae109_4420	1.301e-38	166.0	COG2304@1|root,COG2304@2|Bacteria,1NX8F@1224|Proteobacteria,430QD@68525|delta/epsilon subdivisions,2WVNR@28221|Deltaproteobacteria,2YW4W@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_8422166_4	945713.IALB_1676	2.566e-62	226.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_8422166_0	378806.STAUR_1286	1.091e-114	379.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_8422166_2	324925.Ppha_0327	5.488e-71	244.0	COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi	1090|Chlorobi	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8422166_3	1111069.TCCBUS3UF1_1900	1.972e-70	256.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	3.1.3.1,3.1.3.8	ko:K01077,ko:K01083,ko:K01113,ko:K07093	ko00562,ko00730,ko00790,ko01100,ko02020,map00562,map00730,map00790,map01100,map02020	M00126	R02135,R03371,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,Exo_endo_phos,Phytase,Phytase-like
ZZS2_k127_8422166_7	278957.ABEA03000157_gene616	5.408e-16	88.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia,3K9N5@414999|Opitutae	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_8422166_9	1396141.BATP01000060_gene4657	8.354e-10	70.0	COG2010@1|root,COG2312@1|root,COG3204@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD,Laminin_G_3
ZZS2_k127_8424477_1	1267533.KB906738_gene2186	2.969e-186	599.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
ZZS2_k127_8424477_0	1123508.JH636442_gene3935	4.346e-217	680.0	COG1228@1|root,COG1228@2|Bacteria,2IYHF@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_8424477_6	314230.DSM3645_26619	3.681e-57	210.0	COG2267@1|root,COG2267@2|Bacteria,2IZJN@203682|Planctomycetes	203682|Planctomycetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS2_k127_8424477_7	452637.Oter_2774	4.964e-48	177.0	COG0693@1|root,COG0693@2|Bacteria,46SYG@74201|Verrucomicrobia,3K830@414999|Opitutae	414999|Opitutae	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
ZZS2_k127_8424477_2	497964.CfE428DRAFT_0141	2.51e-117	392.0	COG1082@1|root,COG4993@1|root,COG1082@2|Bacteria,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
ZZS2_k127_8424477_4	1121468.AUBR01000005_gene31	1.872e-85	302.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,42FC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
ZZS2_k127_8424477_3	316274.Haur_2567	8.808e-110	372.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,376E3@32061|Chloroflexia	32061|Chloroflexia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS2_k127_8424477_9	395019.Bmul_2573	3.712e-07	57.0	COG5393@1|root,COG5393@2|Bacteria,1N5Q0@1224|Proteobacteria,2VV9G@28216|Betaproteobacteria,1K7WT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
ZZS2_k127_8424477_8	452637.Oter_1161	5.914e-13	74.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
ZZS2_k127_8424477_5	1123070.KB899257_gene2284	1.243e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ZZS2_k127_8456149_1	926550.CLDAP_14260	1.482e-137	447.0	COG3173@1|root,COG3173@2|Bacteria,2G5RM@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS2_k127_8456149_0	926550.CLDAP_36730	7.293e-178	567.0	COG1960@1|root,COG1960@2|Bacteria,2G5J5@200795|Chloroflexi	200795|Chloroflexi	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_8460477_4	1396418.BATQ01000157_gene2436	7.296e-67	255.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,46T3W@74201|Verrucomicrobia,2IUFR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
ZZS2_k127_8460477_7	56780.SYN_03077	3.74e-25	110.0	COG5652@1|root,COG5652@2|Bacteria,1PUUC@1224|Proteobacteria,43F3B@68525|delta/epsilon subdivisions,2X381@28221|Deltaproteobacteria,2MSC7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
ZZS2_k127_8460477_6	497964.CfE428DRAFT_4274	5.766e-31	124.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ZZS2_k127_8460477_5	240016.ABIZ01000001_gene766	3.872e-39	158.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
ZZS2_k127_8460477_1	497964.CfE428DRAFT_2029	1.93e-100	338.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
ZZS2_k127_8460477_0	497964.CfE428DRAFT_5142	8e-129	430.0	28I6K@1|root,2Z89I@2|Bacteria,46UMN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8460477_8	102129.Lepto7375DRAFT_5591	3.739e-10	70.0	COG0723@1|root,COG0723@2|Bacteria,1G878@1117|Cyanobacteria,1HC6E@1150|Oscillatoriales	1117|Cyanobacteria	C	Rieske fe-s protein	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
ZZS2_k127_8460477_2	1403819.BATR01000180_gene5997	2.64e-85	287.0	COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,2IUID@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ZZS2_k127_8460477_3	518766.Rmar_0054	4.495e-77	271.0	COG4148@1|root,COG4148@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
ZZS2_k127_8474190_4	525897.Dbac_2170	4.371e-20	95.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,42VD3@68525|delta/epsilon subdivisions,2WRQJ@28221|Deltaproteobacteria,2MDDZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS2_k127_8474190_2	794903.OPIT5_27320	1.196e-85	291.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS2_k127_8474190_0	794903.OPIT5_27315	6.213e-121	396.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	MA20_08125	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_trans_aux,MlaD
ZZS2_k127_8474190_1	292415.Tbd_2287	8.96e-100	331.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VQQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
ZZS2_k127_8474190_3	1121918.ARWE01000001_gene2193	3.477e-78	269.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS2_k127_8474190_6	316067.Geob_0432	3.162e-13	71.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8474190_5	278957.ABEA03000005_gene4416	1.235e-19	89.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
ZZS2_k127_851970_4	497964.CfE428DRAFT_0620	1.969e-95	317.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
ZZS2_k127_851970_1	1396141.BATP01000060_gene4727	3.995e-219	723.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
ZZS2_k127_851970_7	251221.35213566	3.883e-12	80.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_851970_5	449447.MAE_12430	2.529e-36	160.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
ZZS2_k127_851970_3	452637.Oter_3619	4.442e-161	521.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,3K78F@414999|Opitutae	414999|Opitutae	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
ZZS2_k127_851970_6	794903.OPIT5_18580	6.752e-16	90.0	COG2197@1|root,COG2197@2|Bacteria,46YP7@74201|Verrucomicrobia,3K9H6@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ZZS2_k127_851970_2	1403819.BATR01000185_gene6425	6.234e-215	678.0	COG2115@1|root,COG2115@2|Bacteria,46TT2@74201|Verrucomicrobia,2ITJ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_851970_0	886293.Sinac_5128	0.0	1339.0	COG0726@1|root,COG1413@1|root,COG2133@1|root,COG3474@1|root,COG0726@2|Bacteria,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IXJQ@203682|Planctomycetes	203682|Planctomycetes	C	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2,VCBS
ZZS2_k127_854638_2	861299.J421_5977	8.831e-121	399.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
ZZS2_k127_854638_4	1396141.BATP01000060_gene4768	1.461e-40	158.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_854638_9	562970.Btus_2088	7.745e-05	55.0	2DP8P@1|root,3311G@2|Bacteria,1VHNE@1239|Firmicutes,4I0Z1@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_854638_0	1396418.BATQ01000130_gene4880	9.817e-171	546.0	COG3875@1|root,COG3875@2|Bacteria,46TVY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
ZZS2_k127_854638_1	497964.CfE428DRAFT_0655	3.801e-129	417.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
ZZS2_k127_854638_3	452637.Oter_3972	1.137e-77	271.0	COG2870@1|root,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,3K9GM@414999|Opitutae	414999|Opitutae	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS2_k127_854638_6	1396141.BATP01000060_gene4765	1.138e-16	95.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_854638_5	247490.KSU1_D0514	3.222e-27	118.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
ZZS2_k127_8552863_3	344747.PM8797T_27784	5.503e-95	324.0	COG2010@1|root,COG2010@2|Bacteria,2J2QT@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_8552863_1	1123508.JH636441_gene3094	1.263e-185	592.0	COG4102@1|root,COG4102@2|Bacteria,2IXNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_8552863_4	478741.JAFS01000001_gene1997	2.232e-49	190.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,37GE7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_16,TPR_6,YfiO
ZZS2_k127_8552863_5	481448.Minf_1576	5.295e-15	81.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia,37GMQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
ZZS2_k127_8552863_0	1267535.KB906767_gene3736	0.0	1027.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_8552863_2	1303518.CCALI_02844	1.443e-184	589.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
ZZS2_k127_8592546_1	1128427.KB904821_gene4191	1.56e-38	156.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1H9BT@1150|Oscillatoriales	1117|Cyanobacteria	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
ZZS2_k127_8592546_0	1123242.JH636434_gene4114	2.088e-66	237.0	COG3828@1|root,COG3828@2|Bacteria,2J2T0@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
ZZS2_k127_8616737_2	1210884.HG799472_gene14852	4.272e-221	717.0	COG2010@1|root,COG2010@2|Bacteria,2IX85@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
ZZS2_k127_8616737_3	1123508.JH636447_gene7968	1.289e-187	598.0	COG4102@1|root,COG4102@2|Bacteria,2IY1A@203682|Planctomycetes	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_8616737_10	595460.RRSWK_00770	0.0001351	54.0	2EJMI@1|root,33DCE@2|Bacteria,2J1MT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8616737_8	592015.HMPREF1705_00489	7.223e-37	156.0	COG1943@1|root,COG1943@2|Bacteria,3TC5I@508458|Synergistetes	508458|Synergistetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
ZZS2_k127_8616737_0	1396141.BATP01000034_gene4143	0.0	1074.0	COG2010@1|root,COG2010@2|Bacteria,46U0M@74201|Verrucomicrobia,2IV63@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_8616737_1	1396141.BATP01000034_gene4142	1.162e-230	724.0	COG3119@1|root,COG3119@2|Bacteria,46TYJ@74201|Verrucomicrobia,2ITHU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_8616737_6	1396141.BATP01000030_gene3705	2.954e-88	295.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_8616737_5	1396141.BATP01000025_gene978	8.989e-105	379.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
ZZS2_k127_8616737_7	1035191.HMPREF0185_03283	2.684e-47	180.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,2TVH5@28211|Alphaproteobacteria,2KGC5@204458|Caulobacterales	204458|Caulobacterales	J	PFAM tRNA rRNA methyltransferase (SpoU)	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
ZZS2_k127_8616737_4	1303518.CCALI_00276	4.498e-112	376.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,PD40,PSCyt1,WD40
ZZS2_k127_8659289_0	1121904.ARBP01000009_gene4206	1.505e-47	188.0	COG0823@1|root,COG4733@1|root,COG0823@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	DUF5050,Laminin_G_3,PD40,SLH,VCBS,zinc_ribbon_2
ZZS2_k127_8693768_3	227086.JGI_V11_39771	3.522e-05	46.0	KOG0266@1|root,KOG0272@1|root,KOG0266@2759|Eukaryota,KOG0272@2759|Eukaryota	2759|Eukaryota	S	U4 snRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,WD40
ZZS2_k127_8693768_0	452637.Oter_1389	1.777e-157	539.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_8693768_2	502025.Hoch_5605	3.19e-32	147.0	COG0470@1|root,COG0515@1|root,COG2319@1|root,COG0470@2|Bacteria,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,4328Z@68525|delta/epsilon subdivisions,2X7NM@28221|Deltaproteobacteria,2YXMY@29|Myxococcales	28221|Deltaproteobacteria	T	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Peptidase_C14,Pkinase,WD40
ZZS2_k127_8693768_1	1157490.EL26_10740	3.918e-58	213.0	COG4412@1|root,COG4412@2|Bacteria,1UYZF@1239|Firmicutes,4HBRX@91061|Bacilli	91061|Bacilli	S	Immune inhibitor A peptidase M6	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
ZZS2_k127_8699932_4	1396418.BATQ01000007_gene1450	2.458e-39	149.0	COG4102@1|root,COG4102@2|Bacteria,46U3G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_8699932_0	497964.CfE428DRAFT_1054	0.0	1299.0	COG2319@1|root,COG5492@1|root,COG2319@2|Bacteria,COG5492@2|Bacteria,46UFD@74201|Verrucomicrobia	74201|Verrucomicrobia	N	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt1,PSCyt2,PSD1,WD40
ZZS2_k127_8699932_2	1123242.JH636434_gene4069	9.639e-136	441.0	COG0673@1|root,COG0673@2|Bacteria,2IX7B@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_8699932_7	497964.CfE428DRAFT_3099	2.3e-10	69.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	tnp15	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
ZZS2_k127_8699932_8	762211.BSTEL_0923	4.79e-08	64.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CZII@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_8699932_6	497964.CfE428DRAFT_3396	1.041e-34	141.0	2DSGX@1|root,33G2Z@2|Bacteria,46W42@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8699932_3	240016.ABIZ01000001_gene5949	2.22e-68	241.0	COG1526@1|root,COG1526@2|Bacteria,46SPA@74201|Verrucomicrobia,2IUBY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FdhD/NarQ family	-	-	-	-	-	-	-	-	-	-	-	-	FdhD-NarQ
ZZS2_k127_8699932_1	452637.Oter_3077	3.556e-172	579.0	COG2982@1|root,COG2982@2|Bacteria,46VEJ@74201|Verrucomicrobia,3K8PP@414999|Opitutae	414999|Opitutae	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
ZZS2_k127_886876_0	880072.Desac_0517	1.576e-111	388.0	COG0784@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MQVW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg,dCache_1
ZZS2_k127_886876_2	338966.Ppro_3011	1.87e-17	90.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,43CDX@68525|delta/epsilon subdivisions,2X7PU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
ZZS2_k127_886876_1	886293.Sinac_3964	4.335e-94	333.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_927000_7	273075.Ta0027	1.21e-54	203.0	COG0656@1|root,arCOG01619@2157|Archaea	2157|Archaea	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	yafB	-	1.1.1.346	ko:K06222	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
ZZS2_k127_927000_4	768671.ThimaDRAFT_1974	3.687e-102	343.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1WWWT@135613|Chromatiales	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS2_k127_927000_11	290317.Cpha266_1106	2.997e-22	101.0	COG0764@1|root,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabZ	-	3.5.1.108,4.2.1.59	ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA
ZZS2_k127_927000_6	1121403.AUCV01000012_gene4113	1.163e-54	201.0	COG0623@1|root,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS2_k127_927000_5	360910.BAV0089	1.802e-57	217.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	2.3.1.157,2.3.1.79,2.7.7.23	ko:K00661,ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
ZZS2_k127_927000_2	443144.GM21_3178	1.864e-128	419.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,42QD8@68525|delta/epsilon subdivisions,2WMK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
ZZS2_k127_927000_10	933262.AXAM01000037_gene876	1.812e-23	102.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2MP8W@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
ZZS2_k127_927000_1	383372.Rcas_0490	1.08e-190	608.0	COG0318@1|root,COG0318@2|Bacteria,2G5XY@200795|Chloroflexi,37755@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_927000_0	118168.MC7420_555	1.398e-250	789.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ZZS2_k127_927000_3	292415.Tbd_0099	8.392e-125	410.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria	28216|Betaproteobacteria	M	epimerase dehydratase	wbpP	-	5.1.3.6,5.1.3.7	ko:K02473,ko:K08679	ko00520,ko01100,map00520,map01100	-	R00418,R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_927000_8	382464.ABSI01000002_gene4291	1.844e-45	176.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH,Peptidase_M28
ZZS2_k127_927000_13	86416.Clopa_2098	1.14e-10	71.0	2A1FW@1|root,30PPA@2|Bacteria,1UA53@1239|Firmicutes,254CY@186801|Clostridia,36TYS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_927000_9	794903.OPIT5_19020	1.615e-43	169.0	COG1169@1|root,COG1943@1|root,COG1169@2|Bacteria,COG1943@2|Bacteria,46TTI@74201|Verrucomicrobia,3K7NU@414999|Opitutae	414999|Opitutae	HQ	Isochorismate synthase	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
ZZS2_k127_968116_3	1192034.CAP_8537	1.602e-51	189.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,42PKE@68525|delta/epsilon subdivisions,2X99A@28221|Deltaproteobacteria,2Z2QS@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
ZZS2_k127_968116_4	572478.Vdis_0988	2.134e-48	186.0	COG0620@1|root,arCOG01876@2157|Archaea,2XPKF@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
ZZS2_k127_968116_1	344747.PM8797T_24401	3.444e-129	419.0	COG1082@1|root,COG1082@2|Bacteria,2J0SX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_968116_7	153721.MYP_3853	1.08e-06	53.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
ZZS2_k127_968116_2	927677.ALVU02000001_gene4418	3.778e-79	275.0	COG2230@1|root,COG2230@2|Bacteria,1GCZE@1117|Cyanobacteria	1117|Cyanobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ZZS2_k127_968116_5	1122925.KB895378_gene2567	3.659e-41	176.0	COG1409@1|root,COG3250@1|root,COG3291@1|root,COG5492@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
ZZS2_k127_968116_0	1123248.KB893321_gene465	4.127e-240	781.0	COG2133@1|root,COG3291@1|root,COG3391@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NF7B@976|Bacteroidetes,1IWJV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
ZZS2_k127_973989_10	1301100.HG529275_gene1645	7.173e-10	67.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,36JT4@31979|Clostridiaceae	186801|Clostridia	M	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
ZZS2_k127_973989_4	497964.CfE428DRAFT_4167	5.235e-81	278.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
ZZS2_k127_973989_8	1121405.dsmv_2790	6.901e-31	131.0	COG2981@1|root,COG2981@2|Bacteria	2|Bacteria	E	high-affinity sulfate:proton symporter activity	cysZ	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600	-	ko:K06203	-	-	-	-	ko00000	-	-	iJR904.b2413,iYL1228.KPN_02760	EI24
ZZS2_k127_973989_1	497964.CfE428DRAFT_4653	7.569e-228	733.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	SMART helicase c2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
ZZS2_k127_973989_2	1123242.JH636434_gene4307	4.8e-207	659.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
ZZS2_k127_973989_3	452637.Oter_4441	1.847e-121	403.0	COG1538@1|root,COG1538@2|Bacteria,46VDP@74201|Verrucomicrobia,3K94B@414999|Opitutae	414999|Opitutae	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
ZZS2_k127_973989_7	452637.Oter_4442	6.981e-32	136.0	28R4W@1|root,2ZDJ6@2|Bacteria,46WU2@74201|Verrucomicrobia,3K9Q2@414999|Opitutae	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_973989_0	452637.Oter_4443	0.0	1381.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,3K96P@414999|Opitutae	414999|Opitutae	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
ZZS2_k127_973989_6	794903.OPIT5_27275	5.273e-36	143.0	2AVVV@1|root,2ZVXE@2|Bacteria,46WVP@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_973989_5	344747.PM8797T_30449	1.324e-42	178.0	294P7@1|root,2ZS2I@2|Bacteria,2J4KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_973989_9	1210884.HG799462_gene8420	2.858e-18	89.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_989314_4	278957.ABEA03000027_gene1659	4.225e-95	327.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
ZZS2_k127_989314_2	497964.CfE428DRAFT_3408	1.675e-119	410.0	28M0D@1|root,2ZAFE@2|Bacteria,46TXJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative ATP-binding cassette	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran_2
ZZS2_k127_989314_3	1403819.BATR01000178_gene5960	1.377e-98	331.0	COG1082@1|root,COG1082@2|Bacteria,46SR1@74201|Verrucomicrobia,2IW0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_989314_0	497964.CfE428DRAFT_3481	2.941e-207	665.0	COG0443@1|root,COG0443@2|Bacteria,46TYN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
ZZS2_k127_989314_6	452637.Oter_1500	3.218e-27	114.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
ZZS2_k127_989314_5	794903.OPIT5_25600	9.981e-83	280.0	COG1136@1|root,COG1136@2|Bacteria,46XY5@74201|Verrucomicrobia,3K8M1@414999|Opitutae	414999|Opitutae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_989314_1	794903.OPIT5_09095	6.444e-142	461.0	COG0577@1|root,COG0577@2|Bacteria,46TQK@74201|Verrucomicrobia,3K8BY@414999|Opitutae	414999|Opitutae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_989314_7	205922.Pfl01_0468	2.652e-14	82.0	COG0515@1|root,COG0515@2|Bacteria,1MXX9@1224|Proteobacteria,1RQFJ@1236|Gammaproteobacteria,1YM9K@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core	rfaP	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	ko:K02848	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF1260.b3630,iBWG_1329.BWG_3321,iEC042_1314.EC042_3937,iECDH10B_1368.ECDH10B_3812,iECDH1ME8569_1439.ECDH1ME8569_3515,iEcDH1_1363.EcDH1_0075,iJO1366.b3630,iY75_1357.Y75_RS18985	Kdo
ZZS2_k127_990631_2	443144.GM21_3259	6.103e-74	269.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
ZZS2_k127_990631_3	497964.CfE428DRAFT_3893	4.138e-59	208.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS2_k127_990631_5	935866.JAER01000020_gene1604	3.29e-10	68.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4DQUU@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
ZZS2_k127_990631_4	316067.Geob_2610	2.56e-14	74.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
ZZS2_k127_990631_1	452637.Oter_3600	3.476e-94	321.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,3K797@414999|Opitutae	414999|Opitutae	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
ZZS2_k127_990631_0	497964.CfE428DRAFT_3889	4.805e-131	427.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
## 5751 queries scanned
## Total time (seconds): 65.5066020488739
## Rate: 87.79 q/s