## Mon Nov 11 16:09:04 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/ZZS2_bin.25.fa -m mmseqs --itype genome -o ZZS2_bin.25 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/ZZS2_bin.25 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
ZZS2_k127_1035095_2	931627.MycrhDRAFT_4494	1.646e-43	179.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,237P0@1762|Mycobacteriaceae	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
ZZS2_k127_1035095_3	888060.HMPREF9081_2084	7.171e-34	141.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4H3BM@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
ZZS2_k127_1035095_0	314230.DSM3645_16225	2.391e-102	346.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_1035095_7	382464.ABSI01000005_gene1327	9.41e-07	56.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1035095_6	234267.Acid_4736	6.572e-19	103.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
ZZS2_k127_1035095_1	240015.ACP_0612	8.968e-60	217.0	COG1573@1|root,COG1573@2|Bacteria,3Y43G@57723|Acidobacteria,2JJ46@204432|Acidobacteriia	204432|Acidobacteriia	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS2_k127_1035095_5	886293.Sinac_5120	1.568e-27	131.0	COG0542@1|root,COG1450@1|root,COG0542@2|Bacteria,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
ZZS2_k127_1090209_9	290397.Adeh_0078	1.287e-20	98.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1090209_11	502025.Hoch_2512	5.748e-14	78.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1090209_2	1379270.AUXF01000001_gene2205	2.352e-101	372.0	COG0507@1|root,COG0507@2|Bacteria,1ZUIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uncharacterized conserved protein (DUF2075)	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
ZZS2_k127_1090209_0	1379270.AUXF01000001_gene2204	1.256e-163	567.0	COG1074@1|root,COG1074@2|Bacteria,1ZUPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
ZZS2_k127_1090209_1	1379270.AUXF01000001_gene2203	1.546e-157	537.0	COG1330@1|root,COG1330@2|Bacteria,1ZUMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Exodeoxyribonuclease V, gamma subunit	-	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
ZZS2_k127_1090209_10	247490.KSU1_D0413	1.432e-19	106.0	COG0802@1|root,COG0802@2|Bacteria,2J06N@203682|Planctomycetes	203682|Planctomycetes	S	ATPase or kinase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
ZZS2_k127_1090209_8	502025.Hoch_6883	1.309e-24	117.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1090209_7	330214.NIDE3198	1.094e-31	143.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS2_k127_1090209_3	204669.Acid345_0497	4.906e-99	344.0	COG0617@1|root,COG0617@2|Bacteria,3Y3B8@57723|Acidobacteria,2JIIS@204432|Acidobacteriia	204432|Acidobacteriia	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
ZZS2_k127_1090209_12	1440053.JOEI01000005_gene1920	2.415e-13	84.0	COG0382@1|root,COG0382@2|Bacteria,2GK6R@201174|Actinobacteria	201174|Actinobacteria	H	Pfam UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
ZZS2_k127_1090209_6	247490.KSU1_B0252	4.336e-76	278.0	COG0750@1|root,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
ZZS2_k127_1090209_4	667014.Thein_2089	4.109e-97	334.0	COG0743@1|root,COG0743@2|Bacteria,2GHA5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
ZZS2_k127_1090209_5	1121377.KB906398_gene2403	2.88e-94	323.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS2_k127_1093346_0	1121013.P873_04860	5.552e-208	672.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1X4BQ@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_1093346_3	491205.JARQ01000001_gene640	3.011e-18	95.0	COG2010@1|root,COG2010@2|Bacteria,4NQE3@976|Bacteroidetes,1I3M2@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrome_CBB3
ZZS2_k127_1093346_4	1157490.EL26_00270	0.0002001	52.0	COG2010@1|root,COG2010@2|Bacteria,1VG21@1239|Firmicutes,4HPNR@91061|Bacilli,27A1B@186823|Alicyclobacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_1093346_1	1137281.D778_02007	7.515e-55	215.0	COG3278@1|root,COG3278@2|Bacteria,4NIGA@976|Bacteroidetes,1HZJ7@117743|Flavobacteriia	976|Bacteroidetes	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
ZZS2_k127_1093346_2	426355.Mrad2831_6076	2.032e-29	135.0	COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,2TRYP@28211|Alphaproteobacteria,1JS9Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS2_k127_113931_6	32057.KB217478_gene3544	0.0007788	49.0	COG1413@1|root,COG1413@2|Bacteria,1GHRB@1117|Cyanobacteria,1HSJZ@1161|Nostocales	1117|Cyanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_113931_0	518766.Rmar_0925	3.349e-174	588.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
ZZS2_k127_113931_4	1120945.ATUW01000001_gene1497	9.724e-33	137.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4D35X@85005|Actinomycetales	201174|Actinobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564,ko:K02804	ko00520,ko01100,ko02060,map00520,map01100,map02060	M00267	R00765,R05199	RC00017,RC00163,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	Glucosamine_iso
ZZS2_k127_113931_2	861299.J421_3940	3.934e-81	291.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
ZZS2_k127_113931_1	468059.AUHA01000002_gene539	6.526e-87	306.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IQ1I@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
ZZS2_k127_113931_3	1111479.AXAR01000002_gene1799	1.438e-35	138.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,278ZN@186823|Alicyclobacillaceae	91061|Bacilli	G	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS,SIS_2
ZZS2_k127_1164181_0	497964.CfE428DRAFT_1953	2.379e-235	736.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,46SI7@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
ZZS2_k127_1164181_9	1249627.D779_0691	4.094e-33	145.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
ZZS2_k127_1164181_3	378806.STAUR_7389	6.194e-113	392.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria,2YUQR@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
ZZS2_k127_1164181_12	9978.XP_004581842.1	7.528e-10	72.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,48YJP@7742|Vertebrata,3JF6U@40674|Mammalia,35NE9@314146|Euarchontoglires	33208|Metazoa	S	hyaluronan metabolic process	ITIH4	GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA
ZZS2_k127_1164181_13	1121430.JMLG01000019_gene1643	4.254e-07	62.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes,24VD1@186801|Clostridia	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
ZZS2_k127_1164181_11	1303518.CCALI_01706	1.698e-19	98.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1164181_15	720554.Clocl_3799	2.821e-05	55.0	COG3595@1|root,COG3595@2|Bacteria,1VD1Z@1239|Firmicutes,24F2A@186801|Clostridia	186801|Clostridia	S	Putative adhesin	-	-	-	ko:K11621	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF4097
ZZS2_k127_1164181_14	926562.Oweho_3443	4.505e-07	60.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2PA7T@246874|Cryomorphaceae	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_1164181_2	1158318.ATXC01000001_gene1139	3.367e-116	383.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS2_k127_1164181_1	1210884.HG799467_gene13284	8.178e-151	508.0	COG0138@1|root,COG0138@2|Bacteria,2IXB5@203682|Planctomycetes	203682|Planctomycetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
ZZS2_k127_1164181_7	665942.HMPREF1022_03209	1.369e-46	176.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MB0W@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
ZZS2_k127_1164181_5	391625.PPSIR1_20104	8.244e-70	244.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
ZZS2_k127_1164181_6	1142394.PSMK_03880	1.733e-51	193.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS2_k127_1164181_16	1280671.AUJH01000016_gene968	0.0002563	52.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,4BZHS@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferases group 1	epsD	-	-	ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_1164181_4	323261.Noc_1078	7.357e-76	267.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,1RYJU@1236|Gammaproteobacteria,1WYA7@135613|Chromatiales	135613|Chromatiales	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,NAD_binding_8
ZZS2_k127_1164181_8	323261.Noc_1079	4.933e-44	175.0	COG1985@1|root,COG1985@2|Bacteria,1RES9@1224|Proteobacteria,1S3BT@1236|Gammaproteobacteria,1WYR6@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
ZZS2_k127_1164181_10	1207063.P24_12042	3.922e-26	126.0	COG3119@1|root,COG3119@2|Bacteria,1PWEJ@1224|Proteobacteria,2TYVA@28211|Alphaproteobacteria,2JSHG@204441|Rhodospirillales	204441|Rhodospirillales	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1174214_10	1082931.KKY_2239	1.068e-07	60.0	COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3N887@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	OHCU decarboxylase	pucL	-	1.7.3.3,3.5.1.41	ko:K00365,ko:K01452	ko00230,ko00232,ko00520,ko01100,ko01120,map00230,map00232,map00520,map01100,map01120	M00546	R02106,R02333,R07981	RC00166,RC00300,RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox,Polysacc_deac_1
ZZS2_k127_1174214_2	1210884.HG799463_gene9717	3.805e-100	337.0	COG1262@1|root,COG1262@2|Bacteria,2IZNJ@203682|Planctomycetes	203682|Planctomycetes	CO	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_1174214_3	395495.Lcho_1717	1.266e-67	254.0	COG0189@1|root,COG0189@2|Bacteria,1QZYF@1224|Proteobacteria,2VUD3@28216|Betaproteobacteria,1KN14@119065|unclassified Burkholderiales	28216|Betaproteobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1174214_8	379066.GAU_3241	4.326e-19	95.0	2E902@1|root,3339H@2|Bacteria,1ZV2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1174214_11	596153.Alide_2188	1.339e-07	64.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,4AD1X@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
ZZS2_k127_1174214_4	1394178.AWOO02000078_gene2042	1.032e-60	233.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4EGF5@85012|Streptosporangiales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
ZZS2_k127_1174214_6	196162.Noca_1324	4.745e-24	111.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4DQ0I@85009|Propionibacteriales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
ZZS2_k127_1174214_9	251221.35211093	5.33e-15	76.0	COG0127@1|root,COG0127@2|Bacteria,1G033@1117|Cyanobacteria	1117|Cyanobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
ZZS2_k127_1174214_1	439235.Dalk_1804	1.902e-147	502.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MK6C@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
ZZS2_k127_1174214_5	1121929.KB898664_gene1541	1.942e-34	143.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,46ZSX@74385|Gracilibacillus	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
ZZS2_k127_1174214_7	1097668.BYI23_A016750	4.573e-23	115.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,2VHJ0@28216|Betaproteobacteria,1K2K2@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS2_k127_1174214_0	1123508.JH636442_gene4220	2.807e-183	603.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
ZZS2_k127_1174214_12	1254432.SCE1572_13185	3.133e-05	51.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_1192950_5	648757.Rvan_2601	7.295e-48	183.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2U9D3@28211|Alphaproteobacteria,3N8T4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
ZZS2_k127_1192950_7	344747.PM8797T_25826	4.984e-38	162.0	COG0543@1|root,COG0543@2|Bacteria,2IYMI@203682|Planctomycetes	203682|Planctomycetes	C	Dihydroorotate dehydrogenase	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
ZZS2_k127_1192950_6	760568.Desku_3218	1.132e-40	164.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,260P0@186807|Peptococcaceae	186801|Clostridia	S	PFAM Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
ZZS2_k127_1192950_13	483219.LILAB_29405	8.744e-07	62.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_1192950_11	751945.Theos_0352	4.653e-10	70.0	COG0642@1|root,COG2205@2|Bacteria,1WJM3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
ZZS2_k127_1192950_1	237368.SCABRO_00027	3.426e-110	375.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_1192950_12	243231.GSU3038	2.12e-09	67.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WKE1@28221|Deltaproteobacteria,43UIW@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
ZZS2_k127_1192950_10	631362.Thi970DRAFT_04161	4.516e-12	73.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1WYGU@135613|Chromatiales	135613|Chromatiales	N	flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
ZZS2_k127_1192950_9	395493.BegalDRAFT_1115	7.822e-16	86.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
ZZS2_k127_1192950_8	665952.HMPREF1015_00056	6.941e-22	108.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
ZZS2_k127_1192950_14	1380394.JADL01000002_gene1164	0.0001428	55.0	COG2982@1|root,COG2982@2|Bacteria,1MUNH@1224|Proteobacteria,2TT0W@28211|Alphaproteobacteria,2JR60@204441|Rhodospirillales	204441|Rhodospirillales	M	protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
ZZS2_k127_1192950_0	449447.MAE_34920	6.166e-146	480.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1G1DF@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
ZZS2_k127_1192950_2	395495.Lcho_0693	6.19e-102	340.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KIYE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
ZZS2_k127_1192950_4	886293.Sinac_6448	7.629e-58	206.0	COG0503@1|root,COG0503@2|Bacteria,2IZ9H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
ZZS2_k127_1192950_3	1123242.JH636435_gene3020	3.753e-73	261.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_119476_1	382464.ABSI01000007_gene4059	8.742e-63	237.0	COG0457@1|root,COG0457@2|Bacteria,46TNJ@74201|Verrucomicrobia,2IVVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
ZZS2_k127_119476_9	794903.OPIT5_09030	8.336e-18	93.0	COG0810@1|root,COG0810@2|Bacteria,46WRI@74201|Verrucomicrobia,3K8HB@414999|Opitutae	414999|Opitutae	M	Biopolymer transporter TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
ZZS2_k127_119476_7	1156937.MFUM_1010012	5.049e-27	115.0	COG0848@1|root,COG0848@2|Bacteria,46W74@74201|Verrucomicrobia,37GRQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_119476_3	452637.Oter_2347	2.204e-47	190.0	COG0811@1|root,COG0811@2|Bacteria,46VCM@74201|Verrucomicrobia,3K7V1@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS2_k127_119476_5	583355.Caka_2271	1.017e-34	144.0	2E0WS@1|root,32WDT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
ZZS2_k127_119476_0	502025.Hoch_2465	6.112e-86	291.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
ZZS2_k127_119476_4	357808.RoseRS_1412	1.553e-46	175.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_119476_11	1569209.BBPH01000005_gene1630	3.255e-15	88.0	COG0627@1|root,COG0627@2|Bacteria,1QNQ4@1224|Proteobacteria,2V4YC@28211|Alphaproteobacteria,2PY20@265|Paracoccus	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_119476_6	331869.BAL199_30142	1.974e-33	134.0	COG3801@1|root,COG3801@2|Bacteria,1RGZ3@1224|Proteobacteria,2U95Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
ZZS2_k127_119476_8	671143.DAMO_0253	5.98e-21	106.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
ZZS2_k127_119476_12	519989.ECTPHS_07636	2.434e-11	78.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
ZZS2_k127_119476_10	257313.BP3207	6.891e-16	89.0	COG3239@1|root,COG3239@2|Bacteria,1R8YH@1224|Proteobacteria,2VM4A@28216|Betaproteobacteria,3T37B@506|Alcaligenaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
ZZS2_k127_119476_2	1254432.SCE1572_14975	2.101e-48	195.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42S0M@68525|delta/epsilon subdivisions,2WNYE@28221|Deltaproteobacteria,2YVQZ@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS2_k127_1273449_4	1123377.AUIV01000020_gene2442	2.614e-58	218.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,1RRGG@1236|Gammaproteobacteria,1X4YU@135614|Xanthomonadales	135614|Xanthomonadales	EM	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
ZZS2_k127_1273449_5	1242864.D187_003764	7.954e-49	179.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
ZZS2_k127_1273449_12	269797.Mbar_A0933	5.337e-05	55.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7RH@28890|Euryarchaeota	28890|Euryarchaeota	T	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_1273449_8	237368.SCABRO_00699	1.584e-25	109.0	COG0776@1|root,COG0776@2|Bacteria,2J3QM@203682|Planctomycetes	203682|Planctomycetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
ZZS2_k127_1273449_2	886293.Sinac_5158	7.191e-93	321.0	COG0482@1|root,COG0482@2|Bacteria,2IXFF@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
ZZS2_k127_1273449_11	1280390.CBQR020000080_gene1779	8.116e-18	92.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,26Z1J@186822|Paenibacillaceae	91061|Bacilli	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
ZZS2_k127_1273449_1	1125863.JAFN01000001_gene473	1.979e-95	336.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
ZZS2_k127_1273449_0	1125863.JAFN01000001_gene1833	3.616e-127	424.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
ZZS2_k127_1273449_9	1123242.JH636436_gene649	6.98e-23	103.0	COG3682@1|root,COG3682@2|Bacteria,2J0YJ@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
ZZS2_k127_1273449_10	886293.Sinac_7101	1.355e-18	101.0	COG4219@1|root,COG4219@2|Bacteria,2J1Q3@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
ZZS2_k127_1273449_6	686340.Metal_2808	5.481e-48	181.0	COG0560@1|root,COG0560@2|Bacteria,1PIND@1224|Proteobacteria,1S9GK@1236|Gammaproteobacteria,1XEK5@135618|Methylococcales	135618|Methylococcales	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
ZZS2_k127_1273449_7	240016.ABIZ01000001_gene3992	3.823e-37	145.0	COG5531@1|root,COG5531@2|Bacteria,46T1X@74201|Verrucomicrobia,2IWIA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	B	SWIB/MDM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
ZZS2_k127_1273449_3	269799.Gmet_3173	5.334e-70	252.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WJQV@28221|Deltaproteobacteria,43S19@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS2_k127_1278628_6	504472.Slin_0052	8.171e-10	62.0	COG2886@1|root,COG2886@2|Bacteria,4NYD2@976|Bacteroidetes,47S8E@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
ZZS2_k127_1278628_5	485916.Dtox_4045	1.072e-13	77.0	COG2405@1|root,COG2405@2|Bacteria,1V8TD@1239|Firmicutes,24M7T@186801|Clostridia	186801|Clostridia	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
ZZS2_k127_1278628_1	515620.EUBELI_01126	8.902e-53	202.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25V28@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
ZZS2_k127_1278628_2	575540.Isop_1193	1.411e-46	191.0	COG4191@1|root,COG4191@2|Bacteria,2IXRK@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ZZS2_k127_1278628_4	96561.Dole_0392	7.204e-19	102.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
ZZS2_k127_1278628_7	452637.Oter_2233	1.204e-06	60.0	COG2353@1|root,COG2353@2|Bacteria,46VEP@74201|Verrucomicrobia,3K92C@414999|Opitutae	414999|Opitutae	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS2_k127_1278628_0	215803.DB30_1638	1.75e-108	372.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
ZZS2_k127_1278628_3	1500897.JQNA01000002_gene4471	2.855e-38	150.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K034@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_1282192_2	42256.RradSPS_2733	2.639e-74	263.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT,HEAT_2
ZZS2_k127_1282192_0	1444309.JAQG01000019_gene564	6.783e-190	608.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,2750X@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
ZZS2_k127_1282192_1	185453.XP_006861112.1	4.449e-160	526.0	COG1112@1|root,KOG1803@2759|Eukaryota,38E4S@33154|Opisthokonta,3BEEC@33208|Metazoa,3CSH2@33213|Bilateria,484VQ@7711|Chordata,48WXQ@7742|Vertebrata,3J3KS@40674|Mammalia,34SEV@311790|Afrotheria	33208|Metazoa	L	DNA-binding protein SMUBP-2	IGHMBP2	GO:0000049,GO:0000122,GO:0000166,GO:0000976,GO:0000977,GO:0000981,GO:0000982,GO:0001012,GO:0001067,GO:0001078,GO:0001227,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003690,GO:0003697,GO:0003700,GO:0003723,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006355,GO:0006357,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007275,GO:0007399,GO:0007417,GO:0008026,GO:0008094,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0021510,GO:0021515,GO:0021517,GO:0021522,GO:0021953,GO:0022008,GO:0022607,GO:0030154,GO:0030182,GO:0030424,GO:0030426,GO:0030427,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032392,GO:0032501,GO:0032502,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032574,GO:0032575,GO:0032991,GO:0033267,GO:0033554,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036477,GO:0042623,GO:0042995,GO:0043005,GO:0043021,GO:0043022,GO:0043025,GO:0043043,GO:0043139,GO:0043141,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0043603,GO:0043604,GO:0043621,GO:0043933,GO:0044085,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0044877,GO:0045892,GO:0045934,GO:0046483,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050877,GO:0050896,GO:0050905,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097458,GO:0120025,GO:0120038,GO:0140097,GO:0140098,GO:0140110,GO:0150034,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:1990904,GO:1990955,GO:2000112,GO:2000113,GO:2001141	3.6.4.12,3.6.4.13	ko:K19036	-	-	-	-	ko00000,ko01000,ko03009,ko03012	-	-	-	AAA_11,AAA_12,R3H,zf-AN1
ZZS2_k127_1282192_3	1382356.JQMP01000004_gene183	4.117e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1286225_0	880072.Desac_0610	3.813e-139	456.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
ZZS2_k127_1286225_1	446470.Snas_6296	8.977e-118	396.0	COG3550@1|root,COG3550@2|Bacteria,2IBV4@201174|Actinobacteria	201174|Actinobacteria	S	HipA domain protein	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
ZZS2_k127_1286225_5	1121272.KB903251_gene840	8.67e-13	70.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,HTH_31
ZZS2_k127_1286225_2	1120973.AQXL01000133_gene1816	2.767e-92	323.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli	91061|Bacilli	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_1286225_4	869213.JCM21142_41657	1.038e-32	139.0	COG0564@1|root,COG0564@2|Bacteria,4NGB1@976|Bacteroidetes,47MQ7@768503|Cytophagia	976|Bacteroidetes	J	PFAM RNA pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
ZZS2_k127_1286225_3	661478.OP10G_0240	5.595e-49	198.0	COG1626@1|root,COG1626@2|Bacteria	2|Bacteria	G	alpha,alpha-trehalase activity	ygjK	GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716	3.2.1.28	ko:K01194,ko:K03931	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37,GH63	-	Glyco_hydro_63,Trehalase
ZZS2_k127_128774_1	439235.Dalk_3476	8.897e-27	129.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42T39@68525|delta/epsilon subdivisions,2WPHT@28221|Deltaproteobacteria,2MPRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_128774_0	1123508.JH636449_gene7349	3.292e-52	213.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_128774_2	1288298.rosmuc_02317	6.939e-11	71.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,2TV85@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_06780	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1351669_4	1123277.KB893180_gene2343	6.831e-82	289.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,47JP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
ZZS2_k127_1351669_3	1122176.KB903598_gene4712	1.062e-107	384.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
ZZS2_k127_1351669_9	649639.Bcell_3936	5.233e-21	98.0	COG3668@1|root,COG3668@2|Bacteria,1VHZU@1239|Firmicutes,4HSJ4@91061|Bacilli	91061|Bacilli	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ZZS2_k127_1351669_2	1120973.AQXL01000103_gene2526	1.249e-193	640.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,2785H@186823|Alicyclobacillaceae	91061|Bacilli	C	Phosphoenolpyruvate phosphomutase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
ZZS2_k127_1351669_1	562970.Btus_1004	6.427e-205	652.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,27820@186823|Alicyclobacillaceae	91061|Bacilli	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
ZZS2_k127_1351669_0	1396141.BATP01000001_gene5351	0.0	1270.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46UMZ@74201|Verrucomicrobia,2IV99@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
ZZS2_k127_1351669_6	1535287.JP74_18280	1.477e-57	231.0	COG1082@1|root,COG1082@2|Bacteria,1R4TC@1224|Proteobacteria,2U2M8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	isomerase	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_1351669_5	1122604.JONR01000006_gene2572	1.471e-78	278.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1X7AW@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_8
ZZS2_k127_1351669_8	404589.Anae109_2440	8.87e-44	173.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2YV02@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS2_k127_1351669_7	452637.Oter_0829	1.228e-49	188.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_1359487_5	886293.Sinac_7408	1.219e-31	136.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_1359487_6	1123508.JH636442_gene4228	7.142e-14	80.0	COG0319@1|root,COG0319@2|Bacteria,2J0MV@203682|Planctomycetes	203682|Planctomycetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
ZZS2_k127_1359487_2	684949.ATTJ01000001_gene2756	4.012e-88	301.0	COG1702@1|root,COG1702@2|Bacteria,1WIK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	KH_1,LAGLIDADG_3,PhoH
ZZS2_k127_1359487_4	861299.J421_3407	4.857e-32	136.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
ZZS2_k127_1359487_3	314230.DSM3645_07730	1.669e-71	265.0	COG0020@1|root,COG0020@2|Bacteria,2IX6Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
ZZS2_k127_1359487_1	1128421.JAGA01000002_gene306	4.957e-105	385.0	COG0104@1|root,COG0104@2|Bacteria,2NNYU@2323|unclassified Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
ZZS2_k127_1359487_0	383372.Rcas_1968	1.249e-138	458.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
ZZS2_k127_1361233_1	448385.sce5249	1.087e-121	398.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,42U5B@68525|delta/epsilon subdivisions,2WQVN@28221|Deltaproteobacteria,2YWFF@29|Myxococcales	28221|Deltaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS2_k127_1361233_0	1123073.KB899245_gene90	1.6e-128	436.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X88E@135614|Xanthomonadales	135614|Xanthomonadales	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS2_k127_1361233_3	756272.Plabr_2998	1.427e-05	58.0	COG2133@1|root,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
ZZS2_k127_1361233_2	324602.Caur_0649	4.069e-18	93.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
ZZS2_k127_1392252_13	1210884.HG799467_gene13189	1.656e-08	56.0	COG0526@1|root,COG0526@2|Bacteria,2J12A@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
ZZS2_k127_1392252_6	519989.ECTPHS_07611	1.05e-25	108.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria	1224|Proteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
ZZS2_k127_1392252_12	1123242.JH636434_gene4241	6.397e-10	68.0	COG0594@1|root,COG0594@2|Bacteria,2J0QW@203682|Planctomycetes	203682|Planctomycetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
ZZS2_k127_1392252_5	1192034.CAP_5409	5.683e-29	125.0	COG5031@1|root,COG5031@2|Bacteria,1NKS8@1224|Proteobacteria,434J5@68525|delta/epsilon subdivisions,2WYWC@28221|Deltaproteobacteria,2Z0SR@29|Myxococcales	28221|Deltaproteobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1392252_0	344747.PM8797T_15161	2.056e-138	452.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_1392252_14	1131553.JIBI01000002_gene1864	3.359e-08	62.0	2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,2WBFI@28216|Betaproteobacteria,373DI@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1392252_3	56110.Oscil6304_3546	5.1e-41	167.0	COG0438@1|root,COG0438@2|Bacteria,1G4KT@1117|Cyanobacteria,1HCQM@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_1392252_15	1051632.TPY_1796	5.024e-07	59.0	COG1051@1|root,COG1051@2|Bacteria,1V3GU@1239|Firmicutes,25BHJ@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS2_k127_1392252_2	1242864.D187_006918	2.402e-51	207.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_1392252_9	1123388.AQWU01000063_gene2086	2.858e-16	83.0	COG0824@1|root,COG0824@2|Bacteria,1WKH6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
ZZS2_k127_1392252_1	502025.Hoch_0164	9.481e-63	247.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,1Q385@1224|Proteobacteria,433YW@68525|delta/epsilon subdivisions,2X44A@28221|Deltaproteobacteria,2YY7W@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
ZZS2_k127_1392252_10	1280954.HPO_02462	4.615e-14	84.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,43WSG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
ZZS2_k127_1392252_4	1232436.CAPF01000046_gene573	2.904e-31	139.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CVPV@84998|Coriobacteriia	84998|Coriobacteriia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
ZZS2_k127_1392252_8	1242864.D187_005740	9.545e-24	116.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria,2Z3ED@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
ZZS2_k127_1392252_7	583355.Caka_1127	2.407e-25	110.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1392252_11	743721.Psesu_0496	5.868e-10	64.0	COG1506@1|root,COG1506@2|Bacteria,1N75C@1224|Proteobacteria,1RXY1@1236|Gammaproteobacteria,1X51F@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS2_k127_1435744_0	518766.Rmar_0899	5.086e-89	300.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS2_k127_1435744_2	448385.sce1810	2.634e-06	61.0	COG1413@1|root,COG1413@2|Bacteria,1RK8P@1224|Proteobacteria,42VXW@68525|delta/epsilon subdivisions,2WRH4@28221|Deltaproteobacteria,2Z1BY@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_1435744_1	543632.JOJL01000021_gene1003	7.895e-72	247.0	COG0847@1|root,COG0847@2|Bacteria,2GXVF@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF5051,RNase_T
ZZS2_k127_1435744_3	4577.GRMZM2G053637_P01	7.799e-06	57.0	28IXY@1|root,2QR9K@2759|Eukaryota,37S7Y@33090|Viridiplantae,3GG0F@35493|Streptophyta,3KYPA@4447|Liliopsida,3I4KP@38820|Poales	35493|Streptophyta	S	Water Stress and Hypersensitive response	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
ZZS2_k127_1478832_2	671143.DAMO_1544	1.62e-43	177.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ZZS2_k127_1478832_0	1210884.HG799462_gene8556	8.953e-76	273.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_1478832_5	1121952.ATXT01000020_gene1719	2.726e-24	120.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4FKJ0@85023|Microbacteriaceae	201174|Actinobacteria	T	Protein phosphatase 2C	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
ZZS2_k127_1478832_3	105420.BBPO01000029_gene6756	4.309e-38	167.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2NFGQ@228398|Streptacidiphilus	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ZZS2_k127_1478832_1	292459.STH1643	1.996e-75	277.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
ZZS2_k127_1478832_4	886293.Sinac_6072	8.949e-28	124.0	COG0805@1|root,COG0805@2|Bacteria,2IZ9K@203682|Planctomycetes	203682|Planctomycetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
ZZS2_k127_1490670_11	504472.Slin_0766	1.486e-13	82.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,47N2Q@768503|Cytophagia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_1490670_14	1278073.MYSTI_02448	1.331e-10	68.0	COG0457@1|root,COG2312@1|root,COG0457@2|Bacteria,COG2312@2|Bacteria,1N4PI@1224|Proteobacteria	1224|Proteobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1490670_5	305900.GV64_23850	1.276e-55	211.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1XJ7E@135619|Oceanospirillales	135619|Oceanospirillales	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS2_k127_1490670_17	1502852.FG94_00500	1.661e-05	57.0	COG1680@1|root,COG1680@2|Bacteria,1MXHB@1224|Proteobacteria,2VXTZ@28216|Betaproteobacteria,47827@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_1490670_9	566466.NOR53_3671	8.445e-33	128.0	COG2119@1|root,COG2119@2|Bacteria,1N85A@1224|Proteobacteria,1SAAX@1236|Gammaproteobacteria,1JB92@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
ZZS2_k127_1490670_8	740709.A10D4_00860	5.986e-39	169.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,1S0UZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	nhl repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Redoxin,Thioredoxin_8
ZZS2_k127_1490670_4	483219.LILAB_09765	6.232e-72	267.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
ZZS2_k127_1490670_0	204669.Acid345_3065	3.798e-178	575.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
ZZS2_k127_1490670_15	756272.Plabr_4630	4.164e-09	65.0	COG4911@1|root,COG4911@2|Bacteria,2J02T@203682|Planctomycetes	203682|Planctomycetes	S	conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
ZZS2_k127_1490670_19	1227352.C173_06106	0.0002382	50.0	COG2706@1|root,COG2706@2|Bacteria,1UNXV@1239|Firmicutes,4IUU1@91061|Bacilli	91061|Bacilli	G	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
ZZS2_k127_1490670_1	1396418.BATQ01000133_gene4037	9.646e-112	370.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
ZZS2_k127_1490670_12	487796.Flav2ADRAFT_1538	4.659e-13	78.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1HZ91@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS2_k127_1490670_3	1120971.AUCA01000005_gene2286	3.35e-75	261.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,278V8@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_1490670_10	756272.Plabr_1857	2.351e-18	100.0	COG1657@1|root,COG1657@2|Bacteria,2J1Q5@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1490670_7	1244083.CSUNSWCD_302	3.035e-42	163.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,42QUT@68525|delta/epsilon subdivisions,2YNVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
ZZS2_k127_1490670_13	765869.BDW_03245	5.326e-11	73.0	2EQTX@1|root,33IDK@2|Bacteria,1NJ7Q@1224|Proteobacteria,42XE5@68525|delta/epsilon subdivisions,2MTFJ@213481|Bdellovibrionales,2WTE3@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SirB
ZZS2_k127_1490670_6	530564.Psta_0956	1.715e-42	167.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS2_k127_1490670_18	1307761.L21SP2_2866	5.093e-05	55.0	COG0457@1|root,COG0457@2|Bacteria	1307761.L21SP2_2866|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1490670_16	191610.CATYP_06785	2.436e-08	65.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,22KGP@1653|Corynebacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1499450_12	1448860.BBJO01000030_gene222	1.045e-06	50.0	COG1282@1|root,arCOG09400@2157|Archaea,2XV3Y@28890|Euryarchaeota,23U48@183963|Halobacteria	183963|Halobacteria	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
ZZS2_k127_1499450_11	1206725.BAFU01000023_gene3667	3.631e-12	79.0	COG4279@1|root,COG4279@2|Bacteria,2GIYW@201174|Actinobacteria,4FUPN@85025|Nocardiaceae	201174|Actinobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
ZZS2_k127_1499450_3	765420.OSCT_0942	7.315e-180	598.0	COG0553@1|root,COG0553@2|Bacteria,2G7XH@200795|Chloroflexi,374UT@32061|Chloroflexia	200795|Chloroflexi	KL	PFAM SNF2-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
ZZS2_k127_1499450_14	1184267.A11Q_451	5.106e-05	55.0	2DR0H@1|root,339NS@2|Bacteria,1Q21V@1224|Proteobacteria,437PH@68525|delta/epsilon subdivisions,2MUAK@213481|Bdellovibrionales,2X2XV@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
ZZS2_k127_1499450_7	313628.LNTAR_03419	2.58e-57	208.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
ZZS2_k127_1499450_1	243090.RB12683	2.658e-224	707.0	COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
ZZS2_k127_1499450_6	1340493.JNIF01000004_gene1037	9.227e-62	227.0	COG1622@1|root,COG3474@1|root,COG1622@2|Bacteria,COG3474@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	-	-	-	-	-	-	-	-	-	-	COX2,COX2_TM,Cytochrom_C
ZZS2_k127_1499450_8	886293.Sinac_3660	1.108e-49	188.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
ZZS2_k127_1499450_4	1192034.CAP_2028	5.358e-98	335.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1499450_10	518766.Rmar_0225	3.968e-25	119.0	COG2010@1|root,COG2010@2|Bacteria,4PHUX@976|Bacteroidetes,1FJC8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS2_k127_1499450_9	1267535.KB906767_gene1098	2.404e-44	183.0	COG2010@1|root,COG2010@2|Bacteria,3Y3HF@57723|Acidobacteria	57723|Acidobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF3341
ZZS2_k127_1499450_2	344747.PM8797T_11856	2.17e-203	677.0	COG5557@1|root,COG5557@2|Bacteria,2IWYN@203682|Planctomycetes	203682|Planctomycetes	C	Polysulphide reductase	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
ZZS2_k127_1499450_0	324602.Caur_0622	2.694e-255	825.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2G6C1@200795|Chloroflexi,376FK@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
ZZS2_k127_1499450_5	391625.PPSIR1_01117	1.294e-73	255.0	COG3880@1|root,COG3880@2|Bacteria,1RD55@1224|Proteobacteria,42TTE@68525|delta/epsilon subdivisions,2X777@28221|Deltaproteobacteria,2YZVZ@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
ZZS2_k127_1499450_13	1205680.CAKO01000040_gene984	3.03e-06	57.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_1522606_7	4536.ONIVA05G07920.2	3.194e-05	57.0	2CNBU@1|root,2QV2U@2759|Eukaryota,37T4I@33090|Viridiplantae,3GFEA@35493|Streptophyta,3KSD8@4447|Liliopsida,3I3HR@38820|Poales	35493|Streptophyta	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,LRR_8
ZZS2_k127_1522606_1	290397.Adeh_2843	3.413e-104	348.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_1522606_4	1278073.MYSTI_01683	2.274e-57	204.0	COG0783@1|root,COG0783@2|Bacteria,1NF9J@1224|Proteobacteria,42SZJ@68525|delta/epsilon subdivisions,2X6VA@28221|Deltaproteobacteria,2Z062@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
ZZS2_k127_1522606_5	1173022.Cri9333_1445	7.714e-51	192.0	COG0431@1|root,COG0431@2|Bacteria,1G0HA@1117|Cyanobacteria,1HAB8@1150|Oscillatoriales	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS2_k127_1522606_6	717605.Theco_2987	3.492e-42	163.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,26WPV@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0403 family	yphP	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
ZZS2_k127_1522606_2	1242864.D187_007363	1.521e-82	300.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1522606_3	1333998.M2A_0834	8.457e-67	250.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_1522606_0	330214.NIDE1185	0.0	1160.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3J17I@40117|Nitrospirae	40117|Nitrospirae	I	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20,6.2.1.3	ko:K01897,ko:K05939	ko00061,ko00071,ko00564,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00564,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R01406,R04864	RC00004,RC00014,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,Acyltransferase
ZZS2_k127_1547160_16	742818.HMPREF9451_00477	4.883e-56	209.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CUE7@84998|Coriobacteriia	84998|Coriobacteriia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
ZZS2_k127_1547160_10	479434.Sthe_1991	5.662e-81	287.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi,27XZD@189775|Thermomicrobia	189775|Thermomicrobia	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_1547160_17	637389.Acaty_c2507	8.748e-56	210.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,2NCFZ@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
ZZS2_k127_1547160_43	926692.AZYG01000051_gene1870	0.0001822	52.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
ZZS2_k127_1547160_18	1232410.KI421421_gene3863	1.327e-50	198.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
ZZS2_k127_1547160_8	876044.IMCC3088_1378	2.508e-83	301.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
ZZS2_k127_1547160_11	1121430.JMLG01000003_gene623	6.642e-76	287.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_1547160_4	717605.Theco_2322	2.655e-120	403.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,26R8F@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_1547160_28	489653.NLA_4630	6.032e-26	125.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,2KQD8@206351|Neisseriales	206351|Neisseriales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	penA	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
ZZS2_k127_1547160_12	429009.Adeg_1572	7.235e-70	249.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,42EWY@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
ZZS2_k127_1547160_37	1095772.CAHH01000059_gene1401	1.923e-12	76.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
ZZS2_k127_1547160_45	1121468.AUBR01000014_gene2221	0.0005175	51.0	COG1413@1|root,COG1413@2|Bacteria,1V5VI@1239|Firmicutes,24HBT@186801|Clostridia,42G9K@68295|Thermoanaerobacterales	186801|Clostridia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_1547160_9	234267.Acid_5449	2.186e-81	301.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS2_k127_1547160_19	671143.DAMO_2743	2.817e-49	192.0	COG1848@1|root,COG1848@2|Bacteria,2NRZ1@2323|unclassified Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
ZZS2_k127_1547160_40	1265503.KB905160_gene2931	4.9e-07	64.0	COG4313@1|root,COG4313@2|Bacteria,1MXNW@1224|Proteobacteria,1S14R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570,Phenol_MetA_deg
ZZS2_k127_1547160_46	749222.Nitsa_0832	0.0005226	53.0	COG0457@1|root,COG0457@2|Bacteria	749222.Nitsa_0832|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1547160_30	595460.RRSWK_02710	4.382e-20	106.0	COG0457@1|root,COG0457@2|Bacteria,2J1FF@203682|Planctomycetes	203682|Planctomycetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
ZZS2_k127_1547160_23	177437.HRM2_29490	3.652e-41	174.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
ZZS2_k127_1547160_25	1122971.BAME01000004_gene614	1.477e-38	162.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,22XC0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
ZZS2_k127_1547160_29	502025.Hoch_0521	1.238e-22	111.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1547160_15	1379698.RBG1_1C00001G1778	9.31e-64	243.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_1547160_5	1499967.BAYZ01000069_gene1846	1.479e-119	393.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_1547160_42	404589.Anae109_3949	0.0001683	55.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
ZZS2_k127_1547160_26	880071.Fleli_3626	1.604e-28	133.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_1547160_0	1403819.BATR01000075_gene2155	1.632e-251	804.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
ZZS2_k127_1547160_14	234267.Acid_5841	2.761e-67	245.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
ZZS2_k127_1547160_24	530564.Psta_2459	2.427e-39	160.0	COG2267@1|root,COG2267@2|Bacteria,2IYU8@203682|Planctomycetes	203682|Planctomycetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS2_k127_1547160_20	234267.Acid_0784	7.246e-47	188.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
ZZS2_k127_1547160_21	1211815.CBYP010000056_gene3330	1.904e-46	192.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ZZS2_k127_1547160_36	1157632.AQWQ01000008_gene5076	4.248e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_1547160_44	65093.PCC7418_2060	0.0004029	53.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1G3QU@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PPC,Peptidase_C11
ZZS2_k127_1547160_34	1449076.JOOE01000002_gene1279	4.04e-15	85.0	COG1595@1|root,COG1595@2|Bacteria,1RIU9@1224|Proteobacteria,2UF2N@28211|Alphaproteobacteria,2KDZJ@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_1547160_27	1242864.D187_007113	5.393e-28	132.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2YURF@29|Myxococcales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
ZZS2_k127_1547160_6	309801.trd_0084	1.046e-99	358.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
ZZS2_k127_1547160_13	1254432.SCE1572_18550	4.804e-68	245.0	COG4284@1|root,COG4284@2|Bacteria,1Q5YI@1224|Proteobacteria,42QK5@68525|delta/epsilon subdivisions,2WKKW@28221|Deltaproteobacteria,2YVJD@29|Myxococcales	28221|Deltaproteobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
ZZS2_k127_1547160_47	225937.HP15_1664	0.0009174	44.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iECW_1372.ECW_m4079,iECs_1301.ECs4714,iEKO11_1354.EKO11_4576,iG2583_1286.G2583_4574,iSBO_1134.SBO_3791,iSDY_1059.SDY_3968,iSF_1195.SF3854,iSSON_1240.SSON_3952,iS_1188.S3905,iWFL_1372.ECW_m4079,iZ_1308.Z5291	Thioredoxin
ZZS2_k127_1547160_32	530564.Psta_3038	9.523e-18	96.0	COG4099@1|root,COG4099@2|Bacteria,2IYJQ@203682|Planctomycetes	203682|Planctomycetes	S	allantoin biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_1547160_39	1121957.ATVL01000014_gene1459	5.928e-11	70.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1547160_22	1232437.KL662004_gene4524	1.883e-41	164.0	2EKQJ@1|root,33EEC@2|Bacteria,1Q6FB@1224|Proteobacteria,4331H@68525|delta/epsilon subdivisions,2WXFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1547160_1	1121957.ATVL01000014_gene1459	7.045e-152	514.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1547160_2	1121957.ATVL01000014_gene1459	9.358e-146	511.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1547160_31	55529.EKX50261	5.689e-18	100.0	28KFE@1|root,2QSWE@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_legB,TIG,fn3
ZZS2_k127_1547160_7	1079460.ATTQ01000016_gene5421	2.14e-91	331.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
ZZS2_k127_1547160_33	1047013.AQSP01000089_gene1174	2.552e-16	92.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT
ZZS2_k127_1547160_41	156889.Mmc1_3212	0.0001349	53.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
ZZS2_k127_1547160_3	448385.sce2579	5.32e-134	434.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2Z349@29|Myxococcales	28221|Deltaproteobacteria	G	DeoC/LacD family aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
ZZS2_k127_1547160_38	292459.STH2212	5.726e-11	76.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CarboxypepD_reg,HemolysinCabind
ZZS2_k127_158178_1	1237149.C900_04543	4.078e-77	273.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
ZZS2_k127_158178_3	1125863.JAFN01000001_gene1953	8.103e-55	205.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-3	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_158178_5	743299.Acife_2763	8.579e-32	139.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,2NC2H@225057|Acidithiobacillales	225057|Acidithiobacillales	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_158178_4	716544.wcw_0082	1.336e-35	156.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2JFR7@204428|Chlamydiae	204428|Chlamydiae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
ZZS2_k127_158178_6	1089552.KI911559_gene1167	2.659e-24	112.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2JQD5@204441|Rhodospirillales	204441|Rhodospirillales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS2_k127_158178_2	204669.Acid345_2770	2.532e-65	246.0	COG3616@1|root,COG3616@2|Bacteria,3Y5RJ@57723|Acidobacteria,2JNYN@204432|Acidobacteriia	204432|Acidobacteriia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
ZZS2_k127_158178_7	521674.Plim_4194	6.545e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,2J0VX@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_158178_0	1499967.BAYZ01000105_gene3512	3.225e-85	296.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_158178_8	1397666.RS24_00650	1.612e-05	55.0	COG1721@1|root,COG1721@2|Bacteria,1QMD5@1224|Proteobacteria,2UW7B@28211|Alphaproteobacteria,4BSXH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_1597783_4	382464.ABSI01000013_gene1773	2.992e-14	85.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1597783_7	589865.DaAHT2_0748	0.000105	52.0	COG5000@1|root,COG5000@2|Bacteria,1RHDM@1224|Proteobacteria,42SJK@68525|delta/epsilon subdivisions,2WPKX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1597783_0	927658.AJUM01000022_gene1235	1.639e-177	577.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,3XJPB@558415|Marinilabiliaceae	976|Bacteroidetes	EU	Prolyl oligopeptidase family	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS2_k127_1597783_3	1123269.NX02_12905	1.568e-17	91.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U7GY@28211|Alphaproteobacteria,2KCC3@204457|Sphingomonadales	204457|Sphingomonadales	NU	Type II secretion system (T2SS), protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS2_k127_1597783_2	1120970.AUBZ01000002_gene856	5.407e-22	100.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,467BP@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG2165 Type II secretory pathway, pseudopilin PulG	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS2_k127_1597783_6	765911.Thivi_2202	7.838e-05	54.0	COG4970@1|root,COG4970@2|Bacteria,1NA2G@1224|Proteobacteria,1SDES@1236|Gammaproteobacteria,1WZ5F@135613|Chromatiales	135613|Chromatiales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
ZZS2_k127_1597783_5	1232410.KI421418_gene2152	3.375e-05	56.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
ZZS2_k127_1597783_1	684949.ATTJ01000001_gene997	6.115e-118	394.0	COG0172@1|root,COG0172@2|Bacteria,1WJ2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000049,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005524,GO:0008144,GO:0016597,GO:0017076,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0046983,GO:0070905,GO:0097159,GO:0097367,GO:1901265,GO:1901363	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
ZZS2_k127_1748302_3	237368.SCABRO_03478	7.64e-42	156.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
ZZS2_k127_1748302_0	264732.Moth_2432	5.122e-68	237.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
ZZS2_k127_1748302_2	756272.Plabr_2080	2.015e-47	173.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
ZZS2_k127_1748302_4	886293.Sinac_0463	2.497e-41	160.0	COG0099@1|root,COG0099@2|Bacteria,2IZK8@203682|Planctomycetes	203682|Planctomycetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
ZZS2_k127_1748302_6	754252.PFREUD_06030	3.289e-12	72.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
ZZS2_k127_1748302_7	572547.Amico_0651	1.82e-09	64.0	COG0361@1|root,COG0361@2|Bacteria,3TBCB@508458|Synergistetes	508458|Synergistetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS2_k127_1748302_1	97139.C824_01103	1.055e-63	231.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,36ETU@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
ZZS2_k127_1748302_5	344747.PM8797T_12288	6.786e-31	126.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
ZZS2_k127_1815205_4	266940.Krad_3107	2.566e-09	69.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_1815205_0	713587.THITH_03495	1.679e-203	655.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1WX9G@135613|Chromatiales	135613|Chromatiales	C	PFAM Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
ZZS2_k127_1815205_3	235909.GK2812	7.407e-17	93.0	COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,1WGPK@129337|Geobacillus	91061|Bacilli	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
ZZS2_k127_1815205_1	1283283.ATXA01000001_gene471	9.454e-41	155.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4EW1Q@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
ZZS2_k127_1815205_2	344747.PM8797T_24886	6.222e-22	107.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
ZZS2_k127_1848329_10	1123242.JH636435_gene1245	2.639e-05	50.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
ZZS2_k127_1848329_6	1123508.JH636447_gene7972	2.135e-19	99.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_1848329_5	886293.Sinac_1102	5.921e-23	101.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_1848329_7	290397.Adeh_4027	3.742e-12	81.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_1848329_0	882083.SacmaDRAFT_4323	7.032e-139	460.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZPP@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS2_k127_1848329_8	1246448.ANAZ01000014_gene1370	6.988e-12	79.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4EFT8@85012|Streptosporangiales	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS2_k127_1848329_3	639030.JHVA01000001_gene1758	2.588e-56	202.0	COG2318@1|root,COG2318@2|Bacteria,3Y4HW@57723|Acidobacteria,2JJ7C@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS2_k127_1848329_11	702113.PP1Y_Mpl7969	0.0001073	46.0	COG4319@1|root,COG4319@2|Bacteria,1N361@1224|Proteobacteria,2UHUN@28211|Alphaproteobacteria,2KC0T@204457|Sphingomonadales	204457|Sphingomonadales	M	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
ZZS2_k127_1848329_2	1120936.KB907221_gene2224	6.327e-70	254.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4EJB1@85012|Streptosporangiales	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
ZZS2_k127_1848329_1	760117.JN27_12520	4.582e-70	253.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,476V6@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Radical SAM superfamily	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
ZZS2_k127_1848329_4	640081.Dsui_0738	1.094e-44	168.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VSN0@28216|Betaproteobacteria,2KWPR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
ZZS2_k127_1848329_9	1297742.A176_07375	1.922e-05	58.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_1865262_3	1265507.KB899636_gene2083	5.091e-37	142.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1Y48K@135624|Aeromonadales	135624|Aeromonadales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
ZZS2_k127_1865262_0	338966.Ppro_3066	1.426e-102	342.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
ZZS2_k127_1865262_4	247634.GPB2148_333	6.849e-17	93.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,1SBRG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
ZZS2_k127_1865262_2	243233.MCA0894	5.059e-79	287.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XDPG@135618|Methylococcales	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147,ko:K06148,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_1865262_1	279238.Saro_3028	5.777e-91	325.0	COG2010@1|root,COG2010@2|Bacteria,1MUF6@1224|Proteobacteria,2TUZF@28211|Alphaproteobacteria,2K92K@204457|Sphingomonadales	204457|Sphingomonadales	C	Quinohemoprotein amine dehydrogenase, alpha subunit domain IV	-	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
ZZS2_k127_1892723_6	518766.Rmar_0572	2.238e-17	93.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1FIXH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
ZZS2_k127_1892723_0	477184.KYC_09440	0.0	1148.0	COG1112@1|root,COG3727@1|root,COG1112@2|Bacteria,COG3727@2|Bacteria,1MWMG@1224|Proteobacteria,2VHWC@28216|Betaproteobacteria,3T4F2@506|Alcaligenaceae	28216|Betaproteobacteria	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559,GreA_GreB,IstB_IS21,WGR
ZZS2_k127_1892723_1	247490.KSU1_D0514	1.021e-266	917.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
ZZS2_k127_1892723_5	313606.M23134_01127	4.472e-30	142.0	COG3204@1|root,COG3211@1|root,COG4935@1|root,COG3204@2|Bacteria,COG3211@2|Bacteria,COG4935@2|Bacteria,4NJ5V@976|Bacteroidetes,47JPA@768503|Cytophagia	976|Bacteroidetes	G	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS2_k127_1892723_2	56780.SYN_01126	2.005e-126	438.0	COG3204@1|root,COG3204@2|Bacteria,1QVA9@1224|Proteobacteria	1224|Proteobacteria	L	pilus organization	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1892723_4	56780.SYN_01126	5.781e-56	208.0	COG3204@1|root,COG3204@2|Bacteria,1QVA9@1224|Proteobacteria	1224|Proteobacteria	L	pilus organization	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_1892723_3	247490.KSU1_C0546	1.803e-77	285.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,Metallophos,Pur_ac_phosph_N
ZZS2_k127_1982686_6	1192034.CAP_3244	3.459e-31	126.0	COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales	28221|Deltaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
ZZS2_k127_1982686_8	379066.GAU_0801	3.681e-19	102.0	COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Peptidase_M56
ZZS2_k127_1982686_3	1267533.KB906739_gene2491	3.558e-91	318.0	COG0247@1|root,COG0247@2|Bacteria,3Y6NT@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
ZZS2_k127_1982686_9	1521187.JPIM01000027_gene1220	1.554e-15	91.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS2_k127_1982686_1	1123508.JH636448_gene7630	2.751e-133	454.0	COG0277@1|root,COG0277@2|Bacteria,2IXH8@203682|Planctomycetes	203682|Planctomycetes	C	Glycolate oxidase subunit	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS2_k127_1982686_2	1297742.A176_01664	1.825e-95	330.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YW82@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS2_k127_1982686_5	1382304.JNIL01000001_gene367	2.828e-59	216.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,4HU4P@91061|Bacilli	91061|Bacilli	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
ZZS2_k127_1982686_7	340099.Teth39_1834	5.937e-23	108.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,42G3N@68295|Thermoanaerobacterales	186801|Clostridia	E	cyclohydrolase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
ZZS2_k127_1982686_0	1121472.AQWN01000005_gene2370	2.248e-177	580.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2602C@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
ZZS2_k127_1982686_4	1089545.KB913037_gene4722	3.776e-88	313.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria,4E8GH@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_2241253_4	521674.Plim_3807	3.469e-29	137.0	COG0811@1|root,COG0811@2|Bacteria,2IYYI@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS2_k127_2241253_5	314230.DSM3645_09202	1.128e-24	121.0	COG1450@1|root,COG3170@1|root,COG1450@2|Bacteria,COG3170@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
ZZS2_k127_2241253_3	267377.MMP0939	1.41e-32	137.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,23QPZ@183939|Methanococci	183939|Methanococci	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
ZZS2_k127_2241253_0	1142394.PSMK_08370	3.302e-98	346.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ZZS2_k127_2241253_1	234621.RER_13270	1.65e-36	148.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FXVX@85025|Nocardiaceae	201174|Actinobacteria	DM	biosynthesis protein	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
ZZS2_k127_2241253_7	749222.Nitsa_1390	1.997e-13	81.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
ZZS2_k127_2241253_6	518766.Rmar_2739	1.767e-18	101.0	COG1033@1|root,COG1033@2|Bacteria,4PIHC@976|Bacteroidetes,1FJ1U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
ZZS2_k127_2241253_2	66875.JODY01000006_gene2238	3.514e-34	147.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,2H32Y@201174|Actinobacteria	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
ZZS2_k127_2241253_8	1487953.JMKF01000006_gene5582	6.789e-10	68.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pentapeptide,WD40
ZZS2_k127_227049_11	1192034.CAP_7328	0.0002745	52.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2YU1F@29|Myxococcales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
ZZS2_k127_227049_3	247490.KSU1_D0821	3.888e-104	352.0	COG0195@1|root,COG0195@2|Bacteria,2IWY3@203682|Planctomycetes	203682|Planctomycetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
ZZS2_k127_227049_8	251221.35212630	2.655e-07	59.0	COG0454@1|root,COG0456@2|Bacteria,1G5TG@1117|Cyanobacteria	1117|Cyanobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS2_k127_227049_0	215803.DB30_5559	3.305e-247	772.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2YUKX@29|Myxococcales	28221|Deltaproteobacteria	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
ZZS2_k127_227049_1	756272.Plabr_3346	2.52e-159	520.0	COG0733@1|root,COG0733@2|Bacteria,2J29X@203682|Planctomycetes	203682|Planctomycetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
ZZS2_k127_227049_9	1247963.JPHU01000013_gene653	7.242e-06	57.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_227049_10	1242864.D187_000180	4.53e-05	57.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_227049_4	3218.PP1S45_237V6.3	3.038e-91	322.0	COG5285@1|root,KOG3290@2759|Eukaryota,388S9@33090|Viridiplantae	33090|Viridiplantae	I	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
ZZS2_k127_227049_6	886293.Sinac_6565	4.753e-36	150.0	COG1085@1|root,COG1085@2|Bacteria,2IX2C@203682|Planctomycetes	203682|Planctomycetes	C	galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
ZZS2_k127_227049_7	265729.GS18_0217160	1.268e-07	64.0	COG3391@1|root,COG3391@2|Bacteria,1V092@1239|Firmicutes,4HC6J@91061|Bacilli	91061|Bacilli	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
ZZS2_k127_227049_2	583355.Caka_1954	4.926e-128	422.0	COG0766@1|root,COG0766@2|Bacteria,46U7P@74201|Verrucomicrobia,3K78X@414999|Opitutae	414999|Opitutae	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
ZZS2_k127_227049_5	1500893.JQNB01000001_gene2813	1.356e-37	163.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1X49U@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
ZZS2_k127_2297217_3	880073.Calab_3450	7.735e-152	520.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
ZZS2_k127_2297217_29	502025.Hoch_6779	1.395e-21	101.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WT56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS2_k127_2297217_19	583355.Caka_2560	1.495e-63	226.0	COG0225@1|root,COG0225@2|Bacteria,46VCK@74201|Verrucomicrobia,3K83N@414999|Opitutae	414999|Opitutae	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
ZZS2_k127_2297217_32	575540.Isop_2831	3.237e-11	64.0	COG0526@1|root,COG2010@1|root,COG0526@2|Bacteria,COG2010@2|Bacteria,2IYKJ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
ZZS2_k127_2297217_4	886293.Sinac_2770	1.386e-143	474.0	COG0526@1|root,COG0526@2|Bacteria,2IYKJ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
ZZS2_k127_2297217_21	391625.PPSIR1_13023	5.363e-60	219.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,42UPB@68525|delta/epsilon subdivisions,2WS1K@28221|Deltaproteobacteria,2YVR9@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_2297217_30	88036.EFJ10802	1.199e-18	93.0	291KV@1|root,2R8GT@2759|Eukaryota,3810Y@33090|Viridiplantae,3GQY0@35493|Streptophyta	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	IQ
ZZS2_k127_2297217_28	1382306.JNIM01000001_gene4183	6.533e-25	117.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
ZZS2_k127_2297217_22	1121918.ARWE01000001_gene2503	7.948e-54	192.0	COG0450@1|root,COG0450@2|Bacteria,1MYZG@1224|Proteobacteria,42SNG@68525|delta/epsilon subdivisions,2WP3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
ZZS2_k127_2297217_31	1158338.JNLJ01000001_gene575	2.846e-16	81.0	COG0450@1|root,COG0450@2|Bacteria,2G3ZJ@200783|Aquificae	200783|Aquificae	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
ZZS2_k127_2297217_1	717774.Marme_2942	2.014e-194	630.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_2297217_15	414684.RC1_2804	2.953e-101	356.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,2JQBK@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_2297217_14	522306.CAP2UW1_2002	1.885e-103	359.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KQC9@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS2_k127_2297217_13	153948.NAL212_2745	4.171e-107	370.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,372RN@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Phosphate transport system permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_2297217_8	251221.35210569	3.274e-123	403.0	COG0573@1|root,COG0573@2|Bacteria,1G1JR@1117|Cyanobacteria	1117|Cyanobacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_2297217_7	530564.Psta_2805	1.241e-131	430.0	COG0226@1|root,COG0226@2|Bacteria,2IYX0@203682|Planctomycetes	203682|Planctomycetes	P	COG0226 ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
ZZS2_k127_2297217_23	1121918.ARWE01000001_gene3636	2.567e-53	197.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,43SH1@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PhoU domain	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
ZZS2_k127_2297217_20	246197.MXAN_3431	1.366e-61	230.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,42UCF@68525|delta/epsilon subdivisions,2WREI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
ZZS2_k127_2297217_2	1210884.HG799462_gene9165	5.857e-172	561.0	COG2132@1|root,COG2132@2|Bacteria,2IX3N@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS2_k127_2297217_27	215803.DB30_4861	2.828e-35	137.0	2AGBH@1|root,316H2@2|Bacteria,1PXKD@1224|Proteobacteria,434N3@68525|delta/epsilon subdivisions,2X8Y5@28221|Deltaproteobacteria,2Z0ZZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2297217_6	864069.MicloDRAFT_00003580	2.336e-135	450.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,1JR7K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	MA20_17485	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_2297217_34	7230.FBpp0167092	6.393e-05	56.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BDZ9@33208|Metazoa,3CW1H@33213|Bilateria,41VA9@6656|Arthropoda,3SKNK@50557|Insecta,44XMA@7147|Diptera,45QP1@7214|Drosophilidae	33208|Metazoa	S	Domain of unknown function (DUF1736)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
ZZS2_k127_2297217_26	243231.GSU1313	2.828e-41	160.0	COG0599@1|root,COG0599@2|Bacteria,1NBJR@1224|Proteobacteria,42SYS@68525|delta/epsilon subdivisions,2WPQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
ZZS2_k127_2297217_5	330214.NIDE3701	1.68e-139	457.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
ZZS2_k127_2297217_33	1267534.KB906757_gene930	3.458e-06	61.0	COG1595@1|root,COG1595@2|Bacteria,3Y7S5@57723|Acidobacteria,2JMWY@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_2297217_12	1121406.JAEX01000006_gene2156	1.43e-111	376.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2M8EH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
ZZS2_k127_2297217_18	350054.Mflv_0506	1.73e-73	264.0	COG2304@1|root,COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
ZZS2_k127_2297217_10	2340.JV46_04780	1.851e-122	423.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2297217_11	580332.Slit_2078	9.313e-118	402.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2297217_17	1304883.KI912532_gene1605	9.318e-84	298.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,2KVSB@206389|Rhodocyclales	206389|Rhodocyclales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_2297217_16	472759.Nhal_3354	4.142e-98	338.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1WXMI@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
ZZS2_k127_2297217_0	1192034.CAP_4888	4.038e-303	941.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS2_k127_2297217_9	391625.PPSIR1_32759	1.381e-122	406.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_2297217_25	385682.AFSL01000064_gene1700	4.648e-45	186.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,2FQJ1@200643|Bacteroidia,3XJXP@558415|Marinilabiliaceae	976|Bacteroidetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_2297217_24	290397.Adeh_0078	2.471e-49	188.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2298066_1	706191.PANA_2841	2.172e-66	249.0	COG0457@1|root,COG0457@2|Bacteria,1RBMC@1224|Proteobacteria,1S33Y@1236|Gammaproteobacteria,3W2MF@53335|Pantoea	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2298066_3	743719.PaelaDRAFT_5840	5.794e-12	68.0	2C95S@1|root,33HPC@2|Bacteria,1VJZ1@1239|Firmicutes,4I8KU@91061|Bacilli,2703Y@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
ZZS2_k127_2298066_2	926560.KE387023_gene3374	4.039e-41	157.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS2_k127_2298066_0	1210884.HG799473_gene15023	1.05e-141	485.0	COG0823@1|root,COG1506@1|root,COG2866@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG2866@2|Bacteria,2J1EY@203682|Planctomycetes	203682|Planctomycetes	E	Zinc carboxypeptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_M14,Peptidase_S9
ZZS2_k127_2298066_5	362418.IW19_17510	4.291e-05	52.0	2EA05@1|root,3345K@2|Bacteria,4NWKR@976|Bacteroidetes,1I6S5@117743|Flavobacteriia,2NX74@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2319752_1	1123242.JH636436_gene71	2.443e-44	185.0	COG0515@1|root,COG0515@2|Bacteria,2IX09@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1080,FGE-sulfatase,LRR_6,Laminin_G_3,PEGA,Pkinase
ZZS2_k127_2319752_3	500153.JOEK01000002_gene326	6.005e-12	80.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigL	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_2319752_2	794903.OPIT5_14435	4.321e-14	84.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS2_k127_2319752_0	1122218.KB893654_gene2214	6.318e-57	206.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,1JRWT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS2_k127_2426204_1	278963.ATWD01000001_gene2098	4.201e-48	178.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS2_k127_2426204_2	1121930.AQXG01000001_gene1072	1.242e-35	147.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes	976|Bacteroidetes	J	endoribonuclease L-PSP	ridA	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
ZZS2_k127_2426204_3	1122989.KB898578_gene1172	1.523e-07	63.0	COG0526@1|root,COG1073@1|root,COG0526@2|Bacteria,COG1073@2|Bacteria,4PJFM@976|Bacteroidetes,2FSF3@200643|Bacteroidia	976|Bacteroidetes	CO	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AhpC-TSA,Hydrolase_4
ZZS2_k127_2426204_0	521096.Tpau_3603	1.592e-59	226.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
ZZS2_k127_2430328_3	1267535.KB906767_gene3078	7.571e-32	131.0	COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria	57723|Acidobacteria	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
ZZS2_k127_2430328_1	639030.JHVA01000001_gene86	2.112e-93	321.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_2430328_2	204669.Acid345_4377	9.621e-88	314.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JM41@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2430328_0	234267.Acid_1724	6.747e-94	332.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_2430328_4	153948.NAL212_3035	4.137e-22	98.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
ZZS2_k127_2430328_5	551789.ATVJ01000001_gene2551	4.958e-12	71.0	2CQDU@1|root,32SKZ@2|Bacteria,1N111@1224|Proteobacteria,2UD30@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	plasmid stabilization protein	-	-	-	-	-	-	-	-	-	-	-	-	ParD
ZZS2_k127_2453324_2	381666.H16_B1765	3.384e-180	576.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,1K09M@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS2_k127_2453324_3	1386089.N865_16840	8.242e-65	229.0	COG3911@1|root,COG3911@2|Bacteria	2|Bacteria	K	COG3911 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
ZZS2_k127_2453324_0	1499967.BAYZ01000036_gene2439	3.053e-286	930.0	COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria	2|Bacteria	P	Cation transporter/ATPase, N-terminus	yloB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	iYO844.BSU15650	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
ZZS2_k127_2453324_1	706587.Desti_4473	8.904e-237	766.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MRHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
ZZS2_k127_2504583_4	697282.Mettu_0553	7.554e-18	85.0	COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
ZZS2_k127_2504583_0	497964.CfE428DRAFT_5721	1.121e-155	531.0	COG2133@1|root,COG2133@2|Bacteria,46UAQ@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Laminin_G_3
ZZS2_k127_2504583_1	497964.CfE428DRAFT_5722	8.748e-121	413.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
ZZS2_k127_2504583_3	240015.ACP_2339	1.961e-34	149.0	COG0079@1|root,COG0079@2|Bacteria,3Y3M6@57723|Acidobacteria,2JIS3@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_2504583_2	1047013.AQSP01000144_gene930	1.506e-36	145.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,2NNXM@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
ZZS2_k127_2507815_5	485913.Krac_9911	1.227e-10	70.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Gram_pos_anchor
ZZS2_k127_2507815_0	756272.Plabr_0696	0.0	1052.0	COG1413@1|root,COG1413@2|Bacteria,2J0DE@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4132)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132
ZZS2_k127_2507815_2	321327.CYA_2858	1.743e-91	304.0	COG0605@1|root,COG0605@2|Bacteria,1G0N2@1117|Cyanobacteria,1GZSS@1129|Synechococcus	1117|Cyanobacteria	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
ZZS2_k127_2507815_4	1121022.ABENE_20020	1.406e-17	84.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2U0VY@28211|Alphaproteobacteria,2KG9Y@204458|Caulobacterales	204458|Caulobacterales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS2_k127_2507815_1	1121957.ATVL01000014_gene1459	5.051e-149	507.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2507815_3	449447.MAE_61060	6.822e-54	206.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
ZZS2_k127_2513000_2	1280390.CBQR020000110_gene2931	1.453e-83	286.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,26R9K@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS2_k127_2513000_1	1254432.SCE1572_45980	1.26e-99	350.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YY6R@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
ZZS2_k127_2513000_4	426117.M446_3620	3.93e-06	60.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,1JU0D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
ZZS2_k127_2513000_5	1173027.Mic7113_0763	1.301e-05	54.0	COG3609@1|root,COG3609@2|Bacteria,1G9PJ@1117|Cyanobacteria,1HD2Z@1150|Oscillatoriales	1117|Cyanobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
ZZS2_k127_2513000_3	419947.MRA_0081	4.532e-31	132.0	2CYNV@1|root,32T4H@2|Bacteria,2IRMP@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
ZZS2_k127_2513000_0	642492.Clole_2181	6.117e-194	614.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
ZZS2_k127_2513000_6	504472.Slin_1493	0.0006984	52.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,47RR1@768503|Cytophagia	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase,Esterase_phd
ZZS2_k127_2554269_11	1057002.KB905370_gene3017	1.2e-19	102.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,SNase
ZZS2_k127_2554269_8	56110.Oscil6304_1840	9.352e-53	214.0	COG4636@1|root,COG4636@2|Bacteria,1G0VC@1117|Cyanobacteria,1H7UG@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_2554269_9	1123371.ATXH01000008_gene226	2.969e-32	133.0	COG1514@1|root,COG1514@2|Bacteria,2GHRT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
ZZS2_k127_2554269_5	709986.Deima_0541	4.276e-71	265.0	COG1080@1|root,COG1080@2|Bacteria,1WJ4Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
ZZS2_k127_2554269_6	1123355.JHYO01000007_gene408	1.708e-67	239.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,36XIF@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Udp N-acetylglucosamine O-acyltransferase; Domain 2	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
ZZS2_k127_2554269_13	869210.Marky_1925	8.56e-10	72.0	COG0612@1|root,COG0612@2|Bacteria,1WM19@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_2554269_12	186497.PF1314	1.062e-12	79.0	COG1432@1|root,arCOG02408@2157|Archaea,2Y6P8@28890|Euryarchaeota,244ZW@183968|Thermococci	183968|Thermococci	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
ZZS2_k127_2554269_0	502025.Hoch_0026	1.067e-229	736.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
ZZS2_k127_2554269_3	644966.Tmar_0757	2.849e-129	424.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
ZZS2_k127_2554269_14	1336249.JADW01000020_gene2587	8.511e-08	62.0	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,2U9G0@28211|Alphaproteobacteria,4BMJX@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_2554269_4	756272.Plabr_1646	5.193e-72	267.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,2J52D@203682|Planctomycetes	203682|Planctomycetes	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_2554269_7	1049564.TevJSym_af00460	1.504e-55	205.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,1J5DW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
ZZS2_k127_2554269_2	439496.RBY4I_210	1.666e-184	626.0	COG0574@1|root,COG0706@1|root,COG2897@1|root,COG0574@2|Bacteria,COG0706@2|Bacteria,COG2897@2|Bacteria,1Q33X@1224|Proteobacteria,2TV1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GPU	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	60KD_IMP,PEP-utilizers,PPDK_N,Rhodanese
ZZS2_k127_2554269_1	661478.OP10G_1417	2.452e-220	707.0	COG1434@1|root,COG1434@2|Bacteria	2|Bacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,NPCBM
ZZS2_k127_2554269_10	448385.sce1077	3.765e-29	128.0	COG3206@1|root,COG3206@2|Bacteria,1QZTF@1224|Proteobacteria,43CNF@68525|delta/epsilon subdivisions,2X7VS@28221|Deltaproteobacteria,2Z3IM@29|Myxococcales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
ZZS2_k127_2582212_1	316274.Haur_5268	0.0001818	54.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GBIB@200795|Chloroflexi,3780C@32061|Chloroflexia	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
ZZS2_k127_2582212_0	382464.ABSI01000011_gene2917	2.285e-86	321.0	COG1629@1|root,COG4771@2|Bacteria,46TY6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
ZZS2_k127_2614748_3	314230.DSM3645_29751	6.262e-94	349.0	COG2133@1|root,COG2133@2|Bacteria,2IXUJ@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_2614748_5	195103.CPF_0840	1.322e-54	210.0	COG2931@1|root,COG2931@2|Bacteria,1VTM8@1239|Firmicutes,25EQH@186801|Clostridia,36URE@31979|Clostridiaceae	186801|Clostridia	M	hmm pf03415	cloSI	-	3.4.22.8	ko:K08587	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	Peptidase_C11
ZZS2_k127_2614748_8	644282.Deba_0290	3.359e-13	82.0	COG2755@1|root,COG2755@2|Bacteria,1Q639@1224|Proteobacteria,432B9@68525|delta/epsilon subdivisions,2WXB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2614748_0	153721.MYP_489	1.855e-163	523.0	COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes,47NBZ@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_2614748_2	289376.THEYE_A0473	2.158e-139	452.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS2_k127_2614748_4	573370.DMR_03000	4.262e-83	286.0	COG1215@1|root,COG1215@2|Bacteria,1QVXA@1224|Proteobacteria,43CYF@68525|delta/epsilon subdivisions,2X8B0@28221|Deltaproteobacteria,2MAXN@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_2614748_1	502025.Hoch_2521	1.907e-148	490.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria,437HH@68525|delta/epsilon subdivisions,2X2R0@28221|Deltaproteobacteria,2YUEC@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
ZZS2_k127_2614748_7	502025.Hoch_2520	7.895e-22	109.0	2A43J@1|root,30SNM@2|Bacteria,1PBXV@1224|Proteobacteria,43868@68525|delta/epsilon subdivisions,2X3G0@28221|Deltaproteobacteria,2YVXT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2614748_6	1123253.AUBD01000001_gene1670	1.137e-35	148.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1X407@135614|Xanthomonadales	135614|Xanthomonadales	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_2614748_9	204669.Acid345_2310	0.0005588	52.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
ZZS2_k127_2718812_2	351627.Csac_2076	5.081e-60	237.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ZZS2_k127_2718812_0	1254432.SCE1572_15930	1.988e-120	411.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
ZZS2_k127_2718812_3	448385.sce8068	5.752e-46	179.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria,2YV8F@29|Myxococcales	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_2718812_1	1121272.KB903249_gene1515	1.849e-89	316.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2I9U6@201174|Actinobacteria,4DH83@85008|Micromonosporales	201174|Actinobacteria	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
ZZS2_k127_2787069_0	1121957.ATVL01000014_gene1459	8.929e-106	362.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2787069_5	1123508.JH636453_gene5807	1.289e-06	53.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
ZZS2_k127_2787069_3	278963.ATWD01000001_gene4396	3.143e-21	103.0	2DP2V@1|root,330AH@2|Bacteria,3Y5MP@57723|Acidobacteria,2JJZ7@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
ZZS2_k127_2787069_4	1278073.MYSTI_05718	9.245e-09	69.0	COG0823@1|root,COG3291@1|root,COG4932@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
ZZS2_k127_2787069_1	234267.Acid_4722	5.413e-67	246.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria	57723|Acidobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
ZZS2_k127_2787069_2	521674.Plim_3941	7.751e-26	124.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,2IXTF@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_282434_17	1254432.SCE1572_51480	6.093e-06	48.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YWJS@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
ZZS2_k127_282434_7	314230.DSM3645_08557	3.155e-67	248.0	COG1005@1|root,COG1005@2|Bacteria,2IXUX@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
ZZS2_k127_282434_13	316067.Geob_0470	6.187e-16	89.0	COG1143@1|root,COG1143@2|Bacteria,1MZJF@1224|Proteobacteria,42M7S@68525|delta/epsilon subdivisions,2WQKZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI-1	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
ZZS2_k127_282434_18	511995.CFPG_422	0.0002952	53.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,2FPHK@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
ZZS2_k127_282434_14	404589.Anae109_1282	3.965e-14	76.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42WIQ@68525|delta/epsilon subdivisions,2WS3A@28221|Deltaproteobacteria,2Z1V8@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
ZZS2_k127_282434_3	1123508.JH636440_gene2430	2.145e-97	347.0	COG1009@1|root,COG1009@2|Bacteria,2IX10@203682|Planctomycetes	203682|Planctomycetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
ZZS2_k127_282434_2	880073.Calab_2684	3.646e-102	360.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
ZZS2_k127_282434_9	272630.MexAM1_META1p0842	7.43e-50	204.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,1JR8M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS2_k127_282434_0	344747.PM8797T_11469	9.87e-141	456.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_282434_4	575540.Isop_3543	1.039e-93	316.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_282434_10	575540.Isop_3542	5.009e-34	151.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_282434_5	886293.Sinac_1839	6.711e-69	269.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXY5@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA,VWA_2
ZZS2_k127_282434_16	1038860.AXAP01000040_gene2871	1.048e-06	63.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3JTPQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
ZZS2_k127_282434_6	530564.Psta_2910	5.792e-68	248.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_282434_15	521674.Plim_2314	1.372e-12	81.0	COG5183@1|root,COG5183@2|Bacteria,2IY9V@203682|Planctomycetes	203682|Planctomycetes	A	protein ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_282434_8	247490.KSU1_C0166	2.85e-53	208.0	COG0772@1|root,COG0772@2|Bacteria,2IZRI@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
ZZS2_k127_282434_11	891968.Anamo_0450	5.343e-24	119.0	COG0768@1|root,COG0768@2|Bacteria,3TADZ@508458|Synergistetes	508458|Synergistetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
ZZS2_k127_282434_1	1142394.PSMK_14530	1.212e-120	402.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ZZS2_k127_282434_12	67352.JODS01000002_gene1631	5.628e-22	111.0	COG0815@1|root,COG0815@2|Bacteria,2GP5I@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
ZZS2_k127_2847256_2	469371.Tbis_3155	3.868e-96	331.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
ZZS2_k127_2847256_0	247490.KSU1_B0544	5.641e-112	374.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	203682|Planctomycetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
ZZS2_k127_2847256_6	1254432.SCE1572_40760	2.098e-25	114.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria,2YVJV@29|Myxococcales	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
ZZS2_k127_2847256_3	401526.TcarDRAFT_1417	1.248e-38	153.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4H4AW@909932|Negativicutes	909932|Negativicutes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
ZZS2_k127_2847256_9	575540.Isop_2891	1.101e-15	82.0	COG0360@1|root,COG0360@2|Bacteria,2J0U0@203682|Planctomycetes	203682|Planctomycetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
ZZS2_k127_2847256_10	56110.Oscil6304_1153	2.358e-09	65.0	COG0238@1|root,COG0238@2|Bacteria,1G7NE@1117|Cyanobacteria,1HC41@1150|Oscillatoriales	1117|Cyanobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
ZZS2_k127_2847256_4	314230.DSM3645_08757	6.491e-36	141.0	COG0359@1|root,COG0359@2|Bacteria,2IZCC@203682|Planctomycetes	203682|Planctomycetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
ZZS2_k127_2847256_1	1121468.AUBR01000009_gene2165	4.399e-110	382.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,42EU2@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
ZZS2_k127_2847256_5	237368.SCABRO_01494	4.92e-27	128.0	COG0558@1|root,COG0558@2|Bacteria,2IZQ1@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ZZS2_k127_2847256_8	1499967.BAYZ01000095_gene4094	2.074e-16	92.0	COG1267@1|root,COG1267@2|Bacteria,2NPTB@2323|unclassified Bacteria	2|Bacteria	I	Phosphatidylglycerophosphatase A	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195	PgpA
ZZS2_k127_2847256_11	880073.Calab_1892	1.79e-06	60.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
ZZS2_k127_2847256_7	342949.PNA2_1424	7.241e-24	115.0	COG1694@1|root,arCOG01084@2157|Archaea,2XZ0S@28890|Euryarchaeota,244B1@183968|Thermococci	183968|Thermococci	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
ZZS2_k127_2849367_4	247490.KSU1_B0556	0.0005692	43.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_2849367_2	1142394.PSMK_18550	4.981e-20	103.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
ZZS2_k127_2849367_0	502025.Hoch_4458	3.104e-232	739.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
ZZS2_k127_2849367_1	1121382.JQKG01000016_gene1568	6.911e-129	421.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
ZZS2_k127_2849367_3	3641.EOX95297	4.332e-06	56.0	KOG1948@1|root,KOG1948@2759|Eukaryota,37J2Z@33090|Viridiplantae,3G9RC@35493|Streptophyta	35493|Streptophyta	O	Nodal modulator	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_2865760_10	794846.AJQU01000180_gene2209	6.627e-05	54.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,2UEEB@28211|Alphaproteobacteria,4BAW0@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
ZZS2_k127_2865760_7	296591.Bpro_2169	6.691e-12	65.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2VJ6S@28216|Betaproteobacteria,4AA2B@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
ZZS2_k127_2865760_9	1120951.AUBG01000025_gene1839	2.107e-07	64.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,Reprolysin_4,SLH,fn3
ZZS2_k127_2865760_0	1286631.X805_30260	5.148e-298	928.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,1KIYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
ZZS2_k127_2865760_1	864051.BurJ1DRAFT_0503	1.096e-174	553.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,1KKBS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
ZZS2_k127_2865760_8	1469557.JSWF01000017_gene2286	5.878e-10	73.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
ZZS2_k127_2865760_2	497964.CfE428DRAFT_0572	4.844e-77	281.0	COG3488@1|root,COG3488@2|Bacteria,46T3U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
ZZS2_k127_2865760_5	304371.MCP_0247	4.877e-37	160.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
ZZS2_k127_2865760_6	1128421.JAGA01000001_gene2321	8.121e-30	137.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_2865760_3	1128421.JAGA01000002_gene756	2.864e-62	239.0	COG0438@1|root,COG0438@2|Bacteria,2NR6D@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Radical_SAM,SPASM
ZZS2_k127_2865760_4	266117.Rxyl_3109	1.359e-53	201.0	COG1216@1|root,COG1216@2|Bacteria,2HTM1@201174|Actinobacteria,4CPU8@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_2888952_0	1442599.JAAN01000019_gene2377	5.715e-214	689.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,1RQNS@1236|Gammaproteobacteria,1X4XU@135614|Xanthomonadales	135614|Xanthomonadales	C	MFS transporter	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
ZZS2_k127_2888952_9	1122214.AQWH01000039_gene4775	1.341e-54	220.0	COG0331@1|root,COG0331@2|Bacteria,1MW5Y@1224|Proteobacteria,2TT74@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-carrier-protein s-malonyltransferase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
ZZS2_k127_2888952_20	1121946.AUAX01000040_gene5595	3.994e-09	68.0	COG4188@1|root,COG4188@2|Bacteria,2H3T8@201174|Actinobacteria,4DB6E@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.101	ko:K21104	-	-	R11540	-	ko00000,ko01000	-	-	-	Abhydrolase_5,Chlorophyllase2,DLH,Hydrolase_4,PAF-AH_p_II
ZZS2_k127_2888952_11	260799.BAS1528	6.205e-44	177.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus	91061|Bacilli	C	Oxidoreductase	nfrA1	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
ZZS2_k127_2888952_21	398767.Glov_2410	5.978e-08	65.0	COG2068@1|root,COG2068@2|Bacteria,1RAAE@1224|Proteobacteria,42QNZ@68525|delta/epsilon subdivisions,2WMYX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	HD,NTP_transf_3
ZZS2_k127_2888952_12	1125863.JAFN01000001_gene311	8.107e-36	147.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
ZZS2_k127_2888952_13	926560.KE387023_gene1738	1.302e-35	145.0	COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
ZZS2_k127_2888952_6	290397.Adeh_2624	8.017e-74	269.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
ZZS2_k127_2888952_3	383372.Rcas_2477	7.074e-128	419.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
ZZS2_k127_2888952_2	1168067.JAGP01000001_gene1406	2.945e-134	443.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,4604I@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
ZZS2_k127_2888952_10	251221.35213151	1.818e-49	201.0	COG0115@1|root,COG0115@2|Bacteria,1G8CI@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS2_k127_2888952_19	697281.Mahau_2088	4.354e-10	73.0	COG3664@1|root,COG5434@1|root,COG5492@1|root,COG3664@2|Bacteria,COG5434@2|Bacteria,COG5492@2|Bacteria,1UIHA@1239|Firmicutes,25GPW@186801|Clostridia,42IXE@68295|Thermoanaerobacterales	1239|Firmicutes	N	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CBM_6
ZZS2_k127_2888952_24	439235.Dalk_0955	0.0003788	54.0	COG0681@1|root,COG0681@2|Bacteria,1RKJ5@1224|Proteobacteria,431MY@68525|delta/epsilon subdivisions,2WX07@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM signal peptidase I	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
ZZS2_k127_2888952_23	555079.Toce_1794	0.0003788	54.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
ZZS2_k127_2888952_5	1254432.SCE1572_52300	1.634e-87	304.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WNH1@28221|Deltaproteobacteria,2Z329@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
ZZS2_k127_2888952_1	1379698.RBG1_1C00001G0513	9.655e-136	446.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
ZZS2_k127_2888952_22	85643.Tmz1t_3847	8.039e-05	50.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVVC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
ZZS2_k127_2888952_8	861299.J421_5641	1.356e-60	220.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	AP_endonuc_2
ZZS2_k127_2888952_7	760568.Desku_1313	6.275e-70	247.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,260EN@186807|Peptococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
ZZS2_k127_2888952_17	479433.Caci_8915	6.486e-13	81.0	2ES6T@1|root,33JRJ@2|Bacteria,2I9QF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2888952_16	1150864.MILUP08_46041	4.004e-30	130.0	COG0300@1|root,COG0300@2|Bacteria,2GJ1R@201174|Actinobacteria,4DEIT@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_2888952_15	383372.Rcas_2760	2.161e-30	133.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,375KA@32061|Chloroflexia	32061|Chloroflexia	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
ZZS2_k127_2888952_4	1144275.COCOR_06470	2.999e-97	336.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2YV2A@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
ZZS2_k127_2888952_14	1210884.HG799465_gene11378	6.762e-35	142.0	COG1778@1|root,COG1778@2|Bacteria,2IZM6@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
ZZS2_k127_2888952_18	314230.DSM3645_13810	8.569e-11	76.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
ZZS2_k127_2898922_4	1356852.N008_03025	1.128e-139	473.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,47P67@768503|Cytophagia	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
ZZS2_k127_2898922_9	1380394.JADL01000008_gene3672	1.285e-108	386.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,2JUHP@204441|Rhodospirillales	204441|Rhodospirillales	GM	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_2898922_10	1121861.KB899942_gene3805	5.655e-71	254.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2JQ88@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_2898922_0	446470.Snas_1820	1.374e-210	680.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
ZZS2_k127_2898922_11	313596.RB2501_06945	1.032e-63	243.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1HYHP@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrroloquinoline quinone biosynthesis protein PqqB	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
ZZS2_k127_2898922_13	886293.Sinac_3762	1.319e-52	203.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,2IZ1I@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
ZZS2_k127_2898922_16	1049564.TevJSym_ab01780	2.15e-27	128.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMFB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS2_k127_2898922_1	562970.Btus_2647	3.31e-198	637.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,277X2@186823|Alicyclobacillaceae	91061|Bacilli	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
ZZS2_k127_2898922_21	671143.DAMO_1946	1.501e-14	83.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
ZZS2_k127_2898922_17	204669.Acid345_0479	6.315e-20	94.0	COG0633@1|root,COG0633@2|Bacteria,3Y4T7@57723|Acidobacteria,2JJFT@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
ZZS2_k127_2898922_3	204669.Acid345_0480	2.001e-157	517.0	COG0443@1|root,COG0443@2|Bacteria,3Y2F8@57723|Acidobacteria,2JIVF@204432|Acidobacteriia	204432|Acidobacteriia	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
ZZS2_k127_2898922_20	1192034.CAP_5771	1.016e-14	85.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,4386D@68525|delta/epsilon subdivisions,2X3GA@28221|Deltaproteobacteria,2YVYT@29|Myxococcales	28221|Deltaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
ZZS2_k127_2898922_15	1519464.HY22_06350	3.433e-28	124.0	COG0316@1|root,COG0316@2|Bacteria,1FFHP@1090|Chlorobi	1090|Chlorobi	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
ZZS2_k127_2898922_12	1123368.AUIS01000004_gene253	1.033e-58	209.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,2NCUC@225057|Acidithiobacillales	225057|Acidithiobacillales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
ZZS2_k127_2898922_2	1340493.JNIF01000003_gene2016	8.906e-169	542.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria	57723|Acidobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_2898922_19	863365.XHC_3049	3.545e-15	85.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ZZS2_k127_2898922_18	378806.STAUR_1528	3.898e-19	98.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
ZZS2_k127_2898922_22	160492.XF_1191	7.517e-05	55.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1X4BU@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
ZZS2_k127_2898922_6	1454004.AW11_02484	2.641e-112	370.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS2_k127_2898922_7	522306.CAP2UW1_1751	1.883e-111	366.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_2898922_5	522306.CAP2UW1_1750	2.228e-113	375.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_2898922_8	1454004.AW11_02487	4.668e-110	363.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS2_k127_2898922_14	1454004.AW11_02488	8.586e-43	165.0	COG0394@1|root,COG0704@1|root,COG0394@2|Bacteria,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	1.20.4.1,3.1.3.48	ko:K01104,ko:K02039,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	PhoU
ZZS2_k127_2901310_3	886293.Sinac_3177	1.361e-21	106.0	COG4112@1|root,COG4112@2|Bacteria,2IZBE@203682|Planctomycetes	203682|Planctomycetes	S	Phosphoesterase (MutT	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2901310_2	696281.Desru_1519	2.53e-48	197.0	COG4191@1|root,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,24A78@186801|Clostridia,262GC@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
ZZS2_k127_2901310_8	1313172.YM304_41480	0.0001879	53.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
ZZS2_k127_2901310_1	1210884.HG799462_gene8051	6.543e-66	243.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_2901310_0	1210884.HG799462_gene8049	3.004e-69	245.0	COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_2901310_4	2074.JNYD01000015_gene4504	2.153e-18	94.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria	201174|Actinobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
ZZS2_k127_2901310_7	1121121.KB894295_gene4395	9.331e-05	47.0	2DH1M@1|root,2ZY2Y@2|Bacteria,1W68J@1239|Firmicutes,4I0XP@91061|Bacilli,273X4@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2901310_5	1121935.AQXX01000025_gene1583	2.247e-07	53.0	2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2934681_4	1123242.JH636434_gene4544	6.694e-48	188.0	COG2365@1|root,COG2365@2|Bacteria,2IZQ7@203682|Planctomycetes	203682|Planctomycetes	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2,DUF442
ZZS2_k127_2934681_0	483219.LILAB_03385	1.491e-177	566.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS2_k127_2934681_12	1394178.AWOO02000061_gene5981	0.0002641	50.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria,4EJ3W@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_2934681_6	300852.55772730	2.247e-25	122.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS2_k127_2934681_2	234267.Acid_5850	1.146e-63	228.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
ZZS2_k127_2934681_9	243265.plu3684	1.685e-08	65.0	COG3091@1|root,COG3091@2|Bacteria,1RJW4@1224|Proteobacteria,1S70F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the SprT family	sprT	-	-	ko:K02742	-	-	-	-	ko00000	-	-	-	SprT-like,Zn_ribbon_SprT
ZZS2_k127_2934681_10	1096546.WYO_3267	2.578e-08	66.0	COG0546@1|root,COG0546@2|Bacteria,1R6SG@1224|Proteobacteria,2TUUY@28211|Alphaproteobacteria,1JTAY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS2_k127_2934681_7	479433.Caci_5521	1.3e-23	115.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS2_k127_2934681_3	296591.Bpro_3588	9.663e-50	198.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2VHG4@28216|Betaproteobacteria,4ABNH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
ZZS2_k127_2934681_1	861299.J421_4222	1.23e-107	361.0	COG3844@1|root,COG3844@2|Bacteria,1ZTZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
ZZS2_k127_2934681_11	1207063.P24_18854	1.891e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1QZ3F@1224|Proteobacteria,2TY48@28211|Alphaproteobacteria,2JQQM@204441|Rhodospirillales	204441|Rhodospirillales	Q	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
ZZS2_k127_2934681_8	1205753.A989_16073	5.724e-13	75.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X4Y5@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
ZZS2_k127_2934681_5	247490.KSU1_C0398	1.184e-30	131.0	COG0234@1|root,COG0234@2|Bacteria,2J027@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
ZZS2_k127_2942262_1	1201288.M900_A0412	4.001e-16	90.0	COG3677@1|root,COG3677@2|Bacteria,1NUJD@1224|Proteobacteria,42ZJP@68525|delta/epsilon subdivisions,2MTUZ@213481|Bdellovibrionales,2WUVR@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2942262_0	344747.PM8797T_17839	2.066e-157	508.0	COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS2_k127_2978945_10	247490.KSU1_D0595	4.593e-29	131.0	COG0265@1|root,COG0265@2|Bacteria,2J23K@203682|Planctomycetes	203682|Planctomycetes	OT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
ZZS2_k127_2978945_6	8083.ENSXMAP00000013463	2.365e-61	220.0	COG3142@1|root,KOG4013@2759|Eukaryota,39V2G@33154|Opisthokonta,3BGM4@33208|Metazoa,3CYKC@33213|Bilateria,486D8@7711|Chordata,4931E@7742|Vertebrata,4A03S@7898|Actinopterygii	33208|Metazoa	P	cutC copper transporter homolog (E. coli)	CUTC	GO:0000003,GO:0000041,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0007275,GO:0007600,GO:0007610,GO:0008150,GO:0009791,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0018991,GO:0019098,GO:0019233,GO:0022414,GO:0022607,GO:0030001,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0035264,GO:0040007,GO:0040025,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0048513,GO:0048569,GO:0048589,GO:0048609,GO:0048731,GO:0048856,GO:0048878,GO:0050801,GO:0050877,GO:0050896,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0071840,GO:0098771	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
ZZS2_k127_2978945_9	616991.JPOO01000003_gene138	1.812e-41	158.0	COG2203@1|root,COG2203@2|Bacteria,4NNYD@976|Bacteroidetes,1I20K@117743|Flavobacteriia,23HBJ@178469|Arenibacter	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
ZZS2_k127_2978945_0	575540.Isop_1075	4.722e-108	366.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_2978945_14	762376.AXYL_00067	0.0004391	44.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,3T2AB@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
ZZS2_k127_2978945_5	880073.Calab_3333	2.383e-71	258.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_2978945_3	404589.Anae109_2645	2.391e-94	346.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
ZZS2_k127_2978945_2	290397.Adeh_2667	3.142e-102	361.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
ZZS2_k127_2978945_7	1278073.MYSTI_03138	1.049e-56	226.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS2_k127_2978945_1	926550.CLDAP_38230	3.98e-107	358.0	COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
ZZS2_k127_2978945_8	880073.Calab_3577	4.872e-45	176.0	COG3848@1|root,COG3848@2|Bacteria	2|Bacteria	GT	kinase activity	-	-	2.7.3.13,2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K22424	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1080,PEP-utilizers,PPDK_N
ZZS2_k127_2978945_13	234267.Acid_4940	4.53e-05	57.0	COG1409@1|root,COG1657@1|root,COG4412@1|root,COG1409@2|Bacteria,COG1657@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K14647,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	CARDB,Peptidase_M30
ZZS2_k127_2978945_4	530564.Psta_3365	1.04e-93	319.0	COG0042@1|root,COG0042@2|Bacteria,2IYH0@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
ZZS2_k127_2978945_11	889378.Spiaf_0442	1.471e-26	113.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
ZZS2_k127_3087310_5	1279009.ADICEAN_01448	1.566e-23	105.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,47KJC@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM pseudouridine synthase, RluA family	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
ZZS2_k127_3087310_3	404589.Anae109_1378	2.967e-71	262.0	COG0585@1|root,COG0585@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
ZZS2_k127_3087310_2	338963.Pcar_2021	1.703e-100	347.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,43SDS@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase superfamily	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
ZZS2_k127_3087310_4	1396418.BATQ01000163_gene1977	8.429e-43	173.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
ZZS2_k127_3087310_0	583355.Caka_0150	2.269e-132	435.0	COG4102@1|root,COG4102@2|Bacteria,46TRQ@74201|Verrucomicrobia,3K73W@414999|Opitutae	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_3087310_1	1123242.JH636435_gene2908	6.548e-106	366.0	COG2319@1|root,COG2319@2|Bacteria,2IZGW@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
ZZS2_k127_3105450_1	1168289.AJKI01000002_gene2514	4.829e-07	64.0	COG1141@1|root,COG1141@2|Bacteria,4P7D9@976|Bacteroidetes,2FZ83@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
ZZS2_k127_3105450_4	861299.J421_1172	1.078e-06	63.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_3105450_3	67373.JOBF01000003_gene551	8.184e-07	63.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GKQH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
ZZS2_k127_3105450_2	62928.azo0278	7.672e-07	62.0	2EFNF@1|root,339EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3105450_0	670487.Ocepr_1445	2.8e-312	983.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1WIRD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
ZZS2_k127_3188766_0	1163409.UUA_11333	1.447e-261	820.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1X3UR@135614|Xanthomonadales	135614|Xanthomonadales	K	accessory protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
ZZS2_k127_3188766_1	1403819.BATR01000070_gene2104	1.517e-91	328.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_3188766_2	883156.HMPREF9282_01643	3.203e-70	258.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4H22T@909932|Negativicutes	909932|Negativicutes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_3188766_4	756272.Plabr_2125	5.936e-31	142.0	COG0845@1|root,COG0845@2|Bacteria,2IXP7@203682|Planctomycetes	203682|Planctomycetes	M	COG0845 Membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,HlyD_3,HlyD_D23
ZZS2_k127_3188766_3	1167006.UWK_02169	1.473e-43	177.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS2_k127_3234471_6	861299.J421_2550	3.183e-70	241.0	COG0266@1|root,COG0266@2|Bacteria,1ZUR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
ZZS2_k127_3234471_11	42256.RradSPS_0203	9.847e-26	119.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
ZZS2_k127_3234471_4	1229780.BN381_100013	6.8e-99	330.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,3UXE8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
ZZS2_k127_3234471_17	523850.TON_1819	6.462e-07	62.0	COG4745@1|root,arCOG00562@2157|Archaea,2Y6NZ@28890|Euryarchaeota,244ZB@183968|Thermococci	183968|Thermococci	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS2_k127_3234471_10	1323663.AROI01000009_gene3715	2.151e-32	136.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
ZZS2_k127_3234471_12	985054.JQEZ01000001_gene2724	2.401e-23	111.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria,4NBN0@97050|Ruegeria	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS2_k127_3234471_13	1042163.BRLA_c043640	4.854e-18	94.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,4H9MD@91061|Bacilli,26S1Y@186822|Paenibacillaceae	91061|Bacilli	N	Flagellar motor protein	ytxE	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
ZZS2_k127_3234471_14	2045.KR76_12650	1.415e-15	88.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DSRC@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
ZZS2_k127_3234471_9	595460.RRSWK_02833	9.764e-36	149.0	COG0030@1|root,COG0030@2|Bacteria,2IYD7@203682|Planctomycetes	203682|Planctomycetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
ZZS2_k127_3234471_7	1118060.CAGZ01000024_gene520	1.962e-68	259.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CUGG@84998|Coriobacteriia	84998|Coriobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
ZZS2_k127_3234471_0	886293.Sinac_1564	8.807e-183	589.0	COG0568@1|root,COG0568@2|Bacteria,2IXI3@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_3234471_15	1121100.JCM6294_3731	1.123e-07	62.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,4ANFP@815|Bacteroidaceae	976|Bacteroidetes	S	Zinc ribbon domain protein	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
ZZS2_k127_3234471_2	644282.Deba_2879	8.438e-119	405.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
ZZS2_k127_3234471_16	13735.ENSPSIP00000009621	2.822e-07	63.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,4955J@7742|Vertebrata,4CH07@8459|Testudines	33208|Metazoa	S	Inter-alpha-trypsin inhibitor heavy chain	ITIH3	GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0008150,GO:0009892,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA
ZZS2_k127_3234471_5	644966.Tmar_1237	1.504e-96	328.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes	1239|Firmicutes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
ZZS2_k127_3234471_1	479434.Sthe_1355	1.572e-134	456.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS2_k127_3234471_8	1125863.JAFN01000001_gene666	3.619e-53	201.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
ZZS2_k127_3234471_3	204669.Acid345_4596	5.88e-106	366.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
ZZS2_k127_3307555_0	485913.Krac_4654	1.418e-78	274.0	COG0483@1|root,COG0483@2|Bacteria,2G88V@200795|Chloroflexi	200795|Chloroflexi	G	inositol monophosphate 1-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3307555_2	391625.PPSIR1_30923	2.148e-37	154.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria	1224|Proteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074	Metallophos
ZZS2_k127_3307555_1	1336208.JADY01000005_gene1942	1.075e-50	207.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,2JQBH@204441|Rhodospirillales	204441|Rhodospirillales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
ZZS2_k127_3349835_4	1235794.C811_01161	1.483e-46	183.0	COG2265@1|root,COG2265@2|Bacteria,2GP90@201174|Actinobacteria,4CUBH@84998|Coriobacteriia	84998|Coriobacteriia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_U5-meth_tr
ZZS2_k127_3349835_5	379066.GAU_3234	1.05e-39	169.0	2DB97@1|root,32TX2@2|Bacteria,1ZUUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3349835_2	1210884.HG799474_gene15102	1.219e-58	228.0	COG5337@1|root,COG5337@2|Bacteria,2J2HW@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_3349835_1	485913.Krac_4655	1.268e-84	299.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the GHMP kinase family. GalK subfamily	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
ZZS2_k127_3349835_3	886293.Sinac_3549	2.044e-51	210.0	COG0515@1|root,COG0515@2|Bacteria,2IXXT@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_3349835_6	644282.Deba_0290	6.405e-13	81.0	COG2755@1|root,COG2755@2|Bacteria,1Q639@1224|Proteobacteria,432B9@68525|delta/epsilon subdivisions,2WXB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3349835_0	575540.Isop_2695	4.701e-162	538.0	COG1198@1|root,COG1198@2|Bacteria,2IY1F@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
ZZS2_k127_3349835_7	290397.Adeh_0078	4.872e-05	46.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3372808_3	1198452.Jab_2c16080	1.91e-46	170.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,2VJ3H@28216|Betaproteobacteria,476TV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	tauC	-	-	ko:K02050,ko:K15552,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00435,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4	-	-	BPD_transp_1
ZZS2_k127_3372808_0	595460.RRSWK_02411	1.169e-102	340.0	COG1116@1|root,COG1116@2|Bacteria,2IZDH@203682|Planctomycetes	203682|Planctomycetes	P	ABC transporter	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
ZZS2_k127_3372808_5	497964.CfE428DRAFT_0188	4.279e-42	158.0	2EA0N@1|root,33462@2|Bacteria,46WE5@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3372808_10	1197719.A464_918	6.303e-08	63.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,3ZKSC@590|Salmonella	1236|Gammaproteobacteria	J	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
ZZS2_k127_3372808_1	91464.S7335_2539	3.993e-68	254.0	COG1940@1|root,COG1940@2|Bacteria,1G11A@1117|Cyanobacteria,1GZ0N@1129|Synechococcus	1117|Cyanobacteria	G	Transcriptional regulator sugar kinase	xylR	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_3372808_2	1304885.AUEY01000016_gene3048	1.31e-47	192.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions,2WMCC@28221|Deltaproteobacteria,2MIZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS2_k127_3372808_11	701176.VIBRN418_01291	3.172e-06	57.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1XSXZ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
ZZS2_k127_3372808_9	876044.IMCC3088_2840	1.718e-08	59.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria,1JAK0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Pyr_redox_3
ZZS2_k127_3372808_4	1297742.A176_04088	8.068e-45	178.0	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions,2WQI0@28221|Deltaproteobacteria,2YW7K@29|Myxococcales	28221|Deltaproteobacteria	S	DTW	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
ZZS2_k127_3372808_7	1123242.JH636435_gene1454	3.512e-25	114.0	COG0746@1|root,COG0746@2|Bacteria,2J0AI@203682|Planctomycetes	203682|Planctomycetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ZZS2_k127_3372808_8	270374.MELB17_13027	3.298e-17	91.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4647M@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	DUF971,ParA
ZZS2_k127_3375760_10	234267.Acid_6224	1.581e-51	206.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS2_k127_3375760_9	794903.OPIT5_16500	1.331e-51	188.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS2_k127_3375760_12	452637.Oter_2449	6.115e-42	172.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS2_k127_3375760_21	247634.GPB2148_2053	2.593e-06	55.0	2E57Z@1|root,3300G@2|Bacteria,1NBSS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3375760_2	1120971.AUCA01000008_gene1917	4.291e-109	382.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2784A@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_3375760_13	671143.DAMO_0254	1.869e-38	164.0	COG2120@1|root,COG2120@2|Bacteria,2NQ6H@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,PIG-L
ZZS2_k127_3375760_4	1121127.JAFA01000039_gene3305	9.271e-83	301.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,2VGZT@28216|Betaproteobacteria,1K0PD@119060|Burkholderiaceae	28216|Betaproteobacteria	P	chloride channel	clcB	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
ZZS2_k127_3375760_20	595460.RRSWK_03471	1.198e-11	79.0	COG1657@1|root,COG1657@2|Bacteria,2J1Q5@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3375760_3	1242864.D187_000461	1.794e-86	304.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales	28221|Deltaproteobacteria	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
ZZS2_k127_3375760_15	270374.MELB17_13557	1.171e-30	125.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
ZZS2_k127_3375760_14	420324.KI912051_gene6020	1.029e-31	126.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,1JVSN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
ZZS2_k127_3375760_7	215803.DB30_2327	1.776e-67	239.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria,2YUCK@29|Myxococcales	28221|Deltaproteobacteria	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_3375760_1	661478.OP10G_2866	1.86e-157	530.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_3375760_22	1396418.BATQ01000185_gene2133	0.0005549	53.0	COG3203@1|root,COG3420@1|root,COG4782@1|root,COG5184@1|root,COG3203@2|Bacteria,COG3420@2|Bacteria,COG4782@2|Bacteria,COG5184@2|Bacteria,46TZK@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,Pectinesterase
ZZS2_k127_3375760_11	439235.Dalk_1685	3.64e-51	187.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria,2MK5V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
ZZS2_k127_3375760_6	344747.PM8797T_01709	1.401e-76	293.0	COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes	203682|Planctomycetes	M	transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
ZZS2_k127_3375760_0	1123371.ATXH01000003_gene1895	1.747e-252	818.0	COG0653@1|root,COG0653@2|Bacteria,2GGR1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
ZZS2_k127_3375760_17	469383.Cwoe_5515	9.083e-15	88.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_3375760_5	649747.HMPREF0083_05050	3.565e-81	293.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,26TD6@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS2_k127_3375760_18	545243.BAEV01000047_gene3667	1.733e-13	83.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,36K1I@31979|Clostridiaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
ZZS2_k127_3375760_19	886293.Sinac_6088	1.964e-13	79.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
ZZS2_k127_3375760_8	243090.RB6271	3.89e-66	239.0	COG4974@1|root,COG4974@2|Bacteria,2IY3V@203682|Planctomycetes	203682|Planctomycetes	D	tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS2_k127_3443645_4	1123242.JH636435_gene2795	2.698e-44	167.0	COG1595@1|root,COG1595@2|Bacteria,2J3CV@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3443645_1	237368.SCABRO_01734	1.171e-106	361.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX,RgpF
ZZS2_k127_3443645_7	1242864.D187_003565	1.859e-18	93.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3443645_10	671143.DAMO_2744	1.36e-05	50.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N,SIS
ZZS2_k127_3443645_5	555779.Dthio_PD2126	1.512e-42	172.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
ZZS2_k127_3443645_3	595460.RRSWK_02466	2.637e-94	325.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
ZZS2_k127_3443645_2	243090.RB13271	1.129e-98	350.0	COG1181@1|root,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS2_k127_3443645_0	575540.Isop_1644	0.0	1047.0	COG0265@1|root,COG3266@1|root,COG4447@1|root,COG0265@2|Bacteria,COG3266@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4,3.4.21.107	ko:K01179,ko:K04771	ko00500,ko01100,ko01503,ko02020,map00500,map01100,map01503,map02020	M00728	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	PDZ_2,Sortilin-Vps10,Trypsin_2
ZZS2_k127_3443645_11	345341.KUTG_00990	0.000747	50.0	COG0488@1|root,COG2319@1|root,COG0488@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4DZJG@85010|Pseudonocardiales	201174|Actinobacteria	T	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
ZZS2_k127_3443645_9	1136138.JH604622_gene1654	5.482e-10	69.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S6MH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
ZZS2_k127_3443645_8	861299.J421_6349	3.743e-13	73.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
ZZS2_k127_3445576_12	234267.Acid_6689	2.318e-15	83.0	COG2062@1|root,COG2062@2|Bacteria,3Y5YQ@57723|Acidobacteria	57723|Acidobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
ZZS2_k127_3445576_14	1385510.N781_09540	2.662e-07	64.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1UXD9@1239|Firmicutes,4I2J1@91061|Bacilli,2YBSI@289201|Pontibacillus	91061|Bacilli	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3445576_10	518766.Rmar_0039	1.764e-44	173.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1FK5D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
ZZS2_k127_3445576_17	589865.DaAHT2_0748	0.000558	50.0	COG5000@1|root,COG5000@2|Bacteria,1RHDM@1224|Proteobacteria,42SJK@68525|delta/epsilon subdivisions,2WPKX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3445576_18	56780.SYN_01756	0.0006769	52.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria	1224|Proteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
ZZS2_k127_3445576_16	246197.MXAN_6725	9.378e-05	55.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1Q2N3@1224|Proteobacteria,4388W@68525|delta/epsilon subdivisions,2XA2N@28221|Deltaproteobacteria,2YXAB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
ZZS2_k127_3445576_11	1303518.CCALI_01218	1.37e-33	151.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA,PMT_2
ZZS2_k127_3445576_4	246197.MXAN_6633	3.981e-72	265.0	28HUE@1|root,2Z815@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3445576_6	1210884.HG799472_gene14849	9.345e-66	255.0	COG4826@1|root,COG4826@2|Bacteria,2J2TV@203682|Planctomycetes	203682|Planctomycetes	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
ZZS2_k127_3445576_9	1242864.D187_003284	3.682e-53	196.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS2_k127_3445576_2	1128421.JAGA01000001_gene2171	7.438e-110	367.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS2_k127_3445576_1	215803.DB30_1485	9.517e-185	591.0	COG2931@1|root,COG2931@2|Bacteria,1QX4P@1224|Proteobacteria,439K8@68525|delta/epsilon subdivisions,2X4WY@28221|Deltaproteobacteria,2YZS2@29|Myxococcales	28221|Deltaproteobacteria	Q	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
ZZS2_k127_3445576_0	485913.Krac_0793	1.582e-283	928.0	COG0210@1|root,COG1112@1|root,COG2852@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	lidB	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_11,AAA_12,AAA_30,DUF559,HRDC,PDDEXK_1
ZZS2_k127_3445576_13	234267.Acid_7379	1.437e-12	81.0	2A08G@1|root,33ENC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3445576_3	211114.JOEF01000042_gene6072	5.649e-79	276.0	COG2242@1|root,COG2242@2|Bacteria,2I5G0@201174|Actinobacteria,4EE02@85010|Pseudonocardiales	201174|Actinobacteria	H	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PrmA
ZZS2_k127_3445576_8	696747.NIES39_J03480	7.066e-59	226.0	COG2304@1|root,COG2304@2|Bacteria,1G2HT@1117|Cyanobacteria,1H70B@1150|Oscillatoriales	1117|Cyanobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
ZZS2_k127_3445576_5	497964.CfE428DRAFT_1723	2.003e-69	246.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	MA20_17565	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_3445576_7	1313421.JHBV01000016_gene5693	1.08e-60	235.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
ZZS2_k127_3445576_15	192952.MM_0490	6.479e-05	56.0	COG1413@1|root,arCOG02966@2157|Archaea	2157|Archaea	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_3483947_29	314230.DSM3645_09082	0.0001036	50.0	COG1544@1|root,COG1544@2|Bacteria,2J1IM@203682|Planctomycetes	203682|Planctomycetes	J	modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
ZZS2_k127_3483947_19	237368.SCABRO_03127	3.853e-24	111.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
ZZS2_k127_3483947_24	1379270.AUXF01000005_gene735	1.751e-17	87.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ZZS2_k127_3483947_9	1499967.BAYZ01000068_gene1962	1.453e-53	201.0	COG4972@1|root,COG4972@2|Bacteria,2NPF6@2323|unclassified Bacteria	2|Bacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS2_k127_3483947_17	572477.Alvin_3058	1.638e-35	155.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
ZZS2_k127_3483947_0	314230.DSM3645_09102	2.122e-122	423.0	COG1530@1|root,COG1530@2|Bacteria,2IWSS@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
ZZS2_k127_3483947_5	1210884.HG799468_gene13802	8.857e-74	265.0	COG5267@1|root,COG5267@2|Bacteria,2IYR3@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
ZZS2_k127_3483947_7	1489678.RDMS_09310	7.101e-69	256.0	COG4102@1|root,COG4102@2|Bacteria,1WJA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_3483947_10	1284352.AOIG01000013_gene3550	1.138e-51	200.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
ZZS2_k127_3483947_20	530564.Psta_2437	2.504e-23	104.0	COG0261@1|root,COG0261@2|Bacteria,2J0XA@203682|Planctomycetes	203682|Planctomycetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
ZZS2_k127_3483947_18	1123508.JH636445_gene6870	1.345e-26	110.0	COG0211@1|root,COG0211@2|Bacteria,2J04T@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
ZZS2_k127_3483947_4	638303.Thal_0675	2.497e-95	331.0	COG0536@1|root,COG0536@2|Bacteria,2G3N0@200783|Aquificae	200783|Aquificae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
ZZS2_k127_3483947_3	404589.Anae109_3433	4.395e-97	339.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_3483947_1	765912.Thimo_1686	1.339e-110	382.0	COG0480@1|root,COG0480@2|Bacteria,1PMU3@1224|Proteobacteria,1S00P@1236|Gammaproteobacteria,1WXBY@135613|Chromatiales	135613|Chromatiales	J	small GTP-binding protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_3483947_13	344747.PM8797T_12193	3.276e-43	161.0	COG0051@1|root,COG0051@2|Bacteria,2IZQR@203682|Planctomycetes	203682|Planctomycetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
ZZS2_k127_3483947_14	247490.KSU1_C1209	6.677e-39	155.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
ZZS2_k127_3483947_23	706587.Desti_5264	2.591e-19	97.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
ZZS2_k127_3483947_2	247490.KSU1_C1211	2.846e-102	340.0	COG0090@1|root,COG0090@2|Bacteria,2IXD9@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
ZZS2_k127_3483947_16	518766.Rmar_0846	6.515e-36	138.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1FJGN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
ZZS2_k127_3483947_26	1122182.KB903813_gene2396	2.775e-14	84.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4DD68@85008|Micromonosporales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
ZZS2_k127_3483947_6	886293.Sinac_0479	4.913e-69	241.0	COG0092@1|root,COG0092@2|Bacteria,2IWWU@203682|Planctomycetes	203682|Planctomycetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
ZZS2_k127_3483947_12	123214.PERMA_1203	1.074e-49	181.0	COG0197@1|root,COG0197@2|Bacteria,2G41X@200783|Aquificae	200783|Aquificae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
ZZS2_k127_3483947_27	1408419.JHYG01000005_gene516	4.965e-07	54.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,2JUAU@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
ZZS2_k127_3483947_21	243265.plu4717	5.627e-23	102.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
ZZS2_k127_3483947_11	247490.KSU1_C1218	2.908e-50	183.0	COG0093@1|root,COG0093@2|Bacteria,2IZMA@203682|Planctomycetes	203682|Planctomycetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
ZZS2_k127_3483947_25	457396.CSBG_00057	1.765e-15	85.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,36JMF@31979|Clostridiaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
ZZS2_k127_3483947_8	330214.NIDE1323	1.72e-65	237.0	COG0094@1|root,COG0094@2|Bacteria,3J0HN@40117|Nitrospirae	40117|Nitrospirae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
ZZS2_k127_3483947_22	880073.Calab_2139	9.891e-23	98.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
ZZS2_k127_3483947_15	756272.Plabr_2070	1.299e-38	151.0	COG0096@1|root,COG0096@2|Bacteria,2IZ8I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
ZZS2_k127_3483947_28	504728.K649_09520	1.013e-06	56.0	COG0097@1|root,COG0097@2|Bacteria,1WJXT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
ZZS2_k127_3488097_6	1123508.JH636439_gene990	1.932e-43	165.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_3488097_4	1396141.BATP01000060_gene4560	2.34e-94	342.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
ZZS2_k127_3488097_1	497964.CfE428DRAFT_5133	4.397e-140	466.0	COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
ZZS2_k127_3488097_2	223283.PSPTO_5223	4.138e-118	394.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1Z6H8@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	E	Xaa-Pro aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
ZZS2_k127_3488097_0	448385.sce8661	6.025e-254	805.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2YZMG@29|Myxococcales	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
ZZS2_k127_3488097_3	521674.Plim_3456	3.423e-115	411.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_3488097_5	314230.DSM3645_28167	5.813e-52	193.0	COG3039@1|root,COG3039@2|Bacteria,2J1M4@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
ZZS2_k127_3511255_4	491205.JARQ01000005_gene1479	3.225e-15	88.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes,1I4J7@117743|Flavobacteriia,3ZUFF@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
ZZS2_k127_3511255_5	509635.N824_07835	7.646e-15	87.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes,1IUNH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
ZZS2_k127_3511255_0	382464.ABSI01000006_gene852	0.0	1983.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	preT	-	1.2.7.1	ko:K00171,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_6,PFOR_II,POR,POR_N,Pyr_redox_2,Pyr_redox_3,TPP_enzyme_C
ZZS2_k127_3511255_1	1356852.N008_18795	2.389e-73	273.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47KE2@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
ZZS2_k127_3511255_2	886293.Sinac_0140	4.079e-42	166.0	2EGZK@1|root,33ARQ@2|Bacteria,2J4A7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3511255_3	246197.MXAN_5268	2.031e-27	125.0	COG1633@1|root,COG1633@2|Bacteria,1QA00@1224|Proteobacteria,434PZ@68525|delta/epsilon subdivisions,2X8YV@28221|Deltaproteobacteria,2Z13N@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3563752_2	1384054.N790_09130	2.326e-132	432.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,1RZKS@1236|Gammaproteobacteria,1XC7A@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3563752_3	530564.Psta_3451	3.811e-105	366.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_3563752_4	1455608.JDTH01000002_gene1687	3.406e-96	340.0	COG1506@1|root,arCOG01646@2157|Archaea,2XU9I@28890|Euryarchaeota,23RYH@183963|Halobacteria	183963|Halobacteria	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	pop	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
ZZS2_k127_3563752_9	929703.KE386491_gene3836	2.034e-39	155.0	COG0637@1|root,COG0637@2|Bacteria,4NHHK@976|Bacteroidetes,47P9C@768503|Cytophagia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS2_k127_3563752_0	1379270.AUXF01000001_gene2448	8.904e-166	548.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
ZZS2_k127_3563752_15	358681.BBR47_24140	0.0003727	51.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,274A1@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_3563752_13	671143.DAMO_2125	1.129e-17	88.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS2_k127_3563752_16	1267535.KB906767_gene1405	0.0005267	53.0	COG1629@1|root,COG4771@2|Bacteria,3Y9A9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_3563752_10	1449347.JQLN01000006_gene2704	1.005e-38	148.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria,2M3NE@2063|Kitasatospora	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_3563752_1	378806.STAUR_7291	5.795e-153	505.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437UC@68525|delta/epsilon subdivisions,2X33Z@28221|Deltaproteobacteria,2YU4A@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3563752_7	405948.SACE_3168	1.445e-62	223.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4E5A2@85010|Pseudonocardiales	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
ZZS2_k127_3563752_11	1198114.AciX9_0251	2.111e-24	108.0	2EPAY@1|root,33GXQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3563752_14	1156844.KB891815_gene5130	9.348e-05	56.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
ZZS2_k127_3563752_6	1041138.KB890222_gene515	5.866e-63	222.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria,4BEGN@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS2_k127_3563752_5	319003.Bra1253DRAFT_00377	1.182e-66	235.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
ZZS2_k127_3563752_12	1320556.AVBP01000007_gene620	4.184e-20	96.0	COG5580@1|root,COG5580@2|Bacteria	2|Bacteria	O	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS2_k127_3572570_8	1121926.AXWO01000006_gene2646	4.218e-59	220.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,4EXK1@85014|Glycomycetales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ZZS2_k127_3572570_11	882086.SacxiDRAFT_2736	1.124e-35	155.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,4DYC4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ZZS2_k127_3572570_7	575540.Isop_1259	7.67e-67	262.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS2_k127_3572570_2	575540.Isop_1258	3.145e-89	325.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_3572570_4	575540.Isop_1258	3.83e-79	280.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_3572570_12	861299.J421_0738	5.708e-24	119.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ZZS2_k127_3572570_9	575540.Isop_1256	1.227e-38	168.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Ribonuc_L-PSP
ZZS2_k127_3572570_0	1120965.AUBV01000001_gene3192	0.0	1483.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
ZZS2_k127_3572570_14	1200792.AKYF01000017_gene5622	0.0001151	52.0	COG1595@1|root,COG1595@2|Bacteria,1V183@1239|Firmicutes,4IQ36@91061|Bacilli	91061|Bacilli	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3572570_1	388413.ALPR1_05710	1.091e-263	827.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
ZZS2_k127_3572570_3	794903.OPIT5_02740	1.77e-81	284.0	29MQ2@1|root,308MT@2|Bacteria,46Y88@74201|Verrucomicrobia,3K93N@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3572570_6	335543.Sfum_2322	2.888e-68	259.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
ZZS2_k127_3572570_5	338966.Ppro_0417	5.124e-70	255.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,42PA3@68525|delta/epsilon subdivisions,2WM6X@28221|Deltaproteobacteria,43SGF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
ZZS2_k127_3572570_10	583355.Caka_2641	1.133e-37	159.0	2C6BE@1|root,32XBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3572719_10	1116232.AHBF01000116_gene4496	1.863e-49	187.0	COG1213@1|root,COG1213@2|Bacteria,2H3AJ@201174|Actinobacteria	201174|Actinobacteria	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
ZZS2_k127_3572719_13	1132509.C447_05857	3.541e-41	168.0	COG1887@1|root,arCOG04827@2157|Archaea,2XWWM@28890|Euryarchaeota,23VFM@183963|Halobacteria	183963|Halobacteria	M	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
ZZS2_k127_3572719_3	338963.Pcar_0629	1.213e-112	372.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X7JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
ZZS2_k127_3572719_2	388467.A19Y_2947	3.353e-125	428.0	COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1G36U@1117|Cyanobacteria,1HFJ5@1150|Oscillatoriales	1117|Cyanobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
ZZS2_k127_3572719_0	573413.Spirs_4230	4.292e-218	690.0	COG1213@1|root,COG2513@1|root,COG1213@2|Bacteria,COG2513@2|Bacteria,2J5AR@203691|Spirochaetes	203691|Spirochaetes	GIM	Phosphoenolpyruvate phosphomutase	aepX	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
ZZS2_k127_3572719_1	338966.Ppro_2168	7.65e-134	437.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,42WGT@68525|delta/epsilon subdivisions,2WRKR@28221|Deltaproteobacteria,43VRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
ZZS2_k127_3572719_12	1540257.JQMW01000011_gene1589	1.577e-41	173.0	COG2433@1|root,COG2433@2|Bacteria,1VWMV@1239|Firmicutes,24TQQ@186801|Clostridia	186801|Clostridia	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3572719_11	1211813.CAPH01000006_gene1647	3.06e-46	185.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_3572719_9	869210.Marky_1830	1.675e-52	202.0	COG2244@1|root,COG2244@2|Bacteria,1WMH9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
ZZS2_k127_3572719_6	1120950.KB892801_gene1669	4.915e-77	276.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	APH,Choline_kinase
ZZS2_k127_3572719_15	575540.Isop_0069	3.203e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,2J0K1@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
ZZS2_k127_3572719_8	886293.Sinac_2100	1.435e-60	238.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_3572719_5	1538295.JY96_08725	3.722e-78	300.0	COG1680@1|root,COG1680@2|Bacteria,1R62E@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_3572719_4	1380394.JADL01000011_gene3934	9.308e-87	295.0	COG5285@1|root,COG5285@2|Bacteria,1N31I@1224|Proteobacteria,2U12W@28211|Alphaproteobacteria,2JVKY@204441|Rhodospirillales	204441|Rhodospirillales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.46	ko:K21195	ko00440,map00440	-	R10724	RC01107	ko00000,ko00001,ko01000	-	-	-	PhyH
ZZS2_k127_3572719_14	1242864.D187_003640	2.019e-40	174.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
ZZS2_k127_3572719_7	322710.Avin_12280	3.729e-67	262.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act,Peptidase_M26_N
ZZS2_k127_3645175_1	247490.KSU1_C1324	1.486e-46	175.0	COG1957@1|root,COG3055@1|root,COG3204@1|root,COG4932@1|root,COG1957@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	DUF547,Laminin_G_3,Malectin
ZZS2_k127_3645175_0	877455.Metbo_0048	3.159e-57	215.0	COG0477@1|root,arCOG02682@2157|Archaea,2XWP6@28890|Euryarchaeota,23PB6@183925|Methanobacteria	183925|Methanobacteria	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3645175_2	215803.DB30_5316	0.0006725	52.0	COG1716@1|root,COG1716@2|Bacteria,1Q3KB@1224|Proteobacteria,439DB@68525|delta/epsilon subdivisions,2X4N4@28221|Deltaproteobacteria,2YZA4@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
ZZS2_k127_3647483_1	1123242.JH636435_gene2121	3.214e-228	749.0	28KJF@1|root,2Z84W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3647483_11	84531.JMTZ01000001_gene2271	4.722e-20	105.0	COG3291@1|root,COG3420@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3	ko:K01337,ko:K01387,ko:K05994,ko:K08604,ko:K14645,ko:K20276	ko02024,ko05110,ko05111,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Inhibitor_I9,LVIVD,PKD,P_proprotein,Peptidase_M14,Peptidase_S8
ZZS2_k127_3647483_9	379066.GAU_3163	5.69e-22	111.0	COG4403@1|root,COG4403@2|Bacteria	2|Bacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
ZZS2_k127_3647483_10	595494.Tola_1778	8.817e-22	98.0	COG1917@1|root,COG1917@2|Bacteria,1RASA@1224|Proteobacteria	1224|Proteobacteria	S	Pfam Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_3647483_12	595494.Tola_1778	1.561e-15	82.0	COG1917@1|root,COG1917@2|Bacteria,1RASA@1224|Proteobacteria	1224|Proteobacteria	S	Pfam Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_3647483_14	1123377.AUIV01000008_gene1373	9.912e-12	79.0	COG2909@1|root,COG4995@1|root,COG2909@2|Bacteria,COG4995@2|Bacteria,1QUP3@1224|Proteobacteria,1SJ9T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
ZZS2_k127_3647483_15	1210045.ALNP01000032_gene2552	4.006e-08	64.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3647483_3	585531.HMPREF0063_10480	2.403e-67	253.0	COG0823@1|root,COG1404@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,2IC0F@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_3647483_2	1303518.CCALI_00297	6.093e-95	327.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
ZZS2_k127_3647483_0	521674.Plim_0334	0.0	1338.0	COG0458@1|root,COG0458@2|Bacteria,2IXR6@203682|Planctomycetes	203682|Planctomycetes	F	Carbamoylphosphate synthase large subunit	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
ZZS2_k127_3647483_8	1210884.HG799462_gene8434	1.374e-26	121.0	COG0500@1|root,COG0500@2|Bacteria,2J1HV@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_3647483_7	671143.DAMO_0253	1.384e-28	129.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
ZZS2_k127_3647483_13	35754.JNYJ01000032_gene1773	9.254e-15	87.0	2A08G@1|root,30NBR@2|Bacteria,2H1QF@201174|Actinobacteria,4DICX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3647483_4	477184.KYC_08065	1.412e-58	225.0	2DBM1@1|root,2Z9WN@2|Bacteria,1RDCQ@1224|Proteobacteria,2VS26@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3647483_6	75379.Tint_2397	8.227e-45	173.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2VTS2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transporter Component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
ZZS2_k127_3647483_5	1223521.BBJX01000014_gene308	1.019e-50	186.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2VSDD@28216|Betaproteobacteria,4AE6S@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
ZZS2_k127_3647483_16	285535.JOEY01000033_gene9225	2.416e-06	61.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria	201174|Actinobacteria	C	fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
ZZS2_k127_3647483_17	1122138.AQUZ01000041_gene7281	0.0009677	52.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	2.4.1.52	ko:K00712	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	DUF285,Glycos_transf_1,MORN_2
ZZS2_k127_365362_4	68260.JOAY01000040_gene1945	6.448e-34	138.0	COG3758@1|root,COG3758@2|Bacteria,2IFWP@201174|Actinobacteria	201174|Actinobacteria	S	HutD	ves	-	-	ko:K09975	-	-	-	-	ko00000	-	-	-	HutD
ZZS2_k127_365362_2	861299.J421_4536	1.776e-85	312.0	COG2866@1|root,COG2866@2|Bacteria,1ZT9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS2_k127_365362_0	933262.AXAM01000099_gene212	1.946e-121	400.0	COG1373@1|root,COG1373@2|Bacteria,1R9U4@1224|Proteobacteria,42ZPX@68525|delta/epsilon subdivisions,2WV2B@28221|Deltaproteobacteria,2MND9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
ZZS2_k127_365362_6	1150600.ADIARSV_1733	9.617e-10	66.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
ZZS2_k127_365362_3	65071.PYU1_T000223	2.187e-53	195.0	COG0377@1|root,KOG1687@2759|Eukaryota,1MEEA@121069|Pythiales	2759|Eukaryota	C	NADH ubiquinone oxidoreductase. Source PGD	NUO10	GO:0000302,GO:0002118,GO:0002121,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0007275,GO:0007568,GO:0007610,GO:0008150,GO:0008152,GO:0008270,GO:0008340,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0010259,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046914,GO:0048856,GO:0050789,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051128,GO:0051704,GO:0051705,GO:0055086,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0099174,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204,GO:2000331	1.6.5.3,1.6.99.3,3.6.4.13	ko:K03940,ko:K16911	ko00190,ko01100,ko01110,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map01110,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	3.D.1.6	-	-	Oxidored_q6
ZZS2_k127_365362_5	880073.Calab_2691	1.126e-27	126.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
ZZS2_k127_365362_1	880073.Calab_2690	8.86e-111	377.0	COG0649@1|root,COG0649@2|Bacteria,2NNXB@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
ZZS2_k127_3660747_7	344747.PM8797T_03314	0.0003516	49.0	COG1657@1|root,COG1657@2|Bacteria,2J2E1@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_3660747_6	1112204.GPOL_c46530	0.0003366	54.0	COG0477@1|root,COG0477@2|Bacteria,2GJSC@201174|Actinobacteria,4GADG@85026|Gordoniaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
ZZS2_k127_3660747_3	204669.Acid345_2718	5.767e-62	234.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y45M@57723|Acidobacteria,2JIBX@204432|Acidobacteriia	204432|Acidobacteriia	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,SpoIIE
ZZS2_k127_3660747_0	667014.Thein_1033	8.503e-115	383.0	COG1060@1|root,COG1060@2|Bacteria,2GH1Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
ZZS2_k127_3660747_2	247490.KSU1_C1151	2.023e-63	225.0	COG2318@1|root,COG2318@2|Bacteria,2J1FT@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
ZZS2_k127_3660747_4	394.NGR_c28870	3.117e-46	179.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,4BMXQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS2_k127_3660747_1	713586.KB900536_gene2659	1.994e-92	317.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
ZZS2_k127_3664474_10	1117647.M5M_13590	7.517e-06	48.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1J8XH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
ZZS2_k127_3664474_4	648757.Rvan_0034	1.107e-121	404.0	COG1063@1|root,COG1063@2|Bacteria,1QTU5@1224|Proteobacteria,2TW9Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	yphC	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
ZZS2_k127_3664474_1	648757.Rvan_0035	9.144e-146	479.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS2_k127_3664474_6	316067.Geob_0098	3.024e-71	249.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS2_k127_3664474_3	85643.Tmz1t_2951	4.779e-136	455.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
ZZS2_k127_3664474_0	316055.RPE_0607	2.359e-191	625.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
ZZS2_k127_3664474_2	1232410.KI421421_gene3272	1.08e-143	468.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2X5NK@28221|Deltaproteobacteria,43W2S@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
ZZS2_k127_3664474_5	85643.Tmz1t_2948	3.55e-96	323.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales	206389|Rhodocyclales	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
ZZS2_k127_3664474_7	648757.Rvan_0041	4.819e-47	191.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2U2FQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_3664474_8	1187851.A33M_3201	5.501e-36	143.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS2_k127_3664474_9	1144275.COCOR_01204	7.866e-25	109.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,Hemerythrin,NnrS
ZZS2_k127_3690491_1	1047013.AQSP01000134_gene1356	3.234e-201	668.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,Peptidase_S9
ZZS2_k127_3690491_5	1144275.COCOR_06922	4.095e-38	166.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS2_k127_3690491_4	1192034.CAP_4484	1.584e-42	176.0	COG1621@1|root,COG1807@1|root,COG1621@2|Bacteria,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3690491_7	234267.Acid_7571	7.058e-26	120.0	COG0823@1|root,COG0823@2|Bacteria,3Y95P@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_3690491_0	1121428.DESHY_150039___1	1.117e-236	753.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2600F@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_3690491_11	1532558.JL39_03420	2.551e-11	68.0	COG3806@1|root,COG3806@2|Bacteria,1RKIS@1224|Proteobacteria,2U9JN@28211|Alphaproteobacteria,4BBFG@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	anti-sigma factor	chrR	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7
ZZS2_k127_3690491_6	1382306.JNIM01000001_gene2680	5.888e-29	126.0	COG0720@1|root,COG0720@2|Bacteria,2G919@200795|Chloroflexi	200795|Chloroflexi	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
ZZS2_k127_3690491_8	1123368.AUIS01000019_gene1220	2.815e-25	111.0	COG0662@1|root,COG0662@2|Bacteria,1N7Q4@1224|Proteobacteria,1SEVR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_3690491_10	702113.PP1Y_AT10241	1.563e-13	83.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2U5YV@28211|Alphaproteobacteria,2K07E@204457|Sphingomonadales	204457|Sphingomonadales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
ZZS2_k127_3690491_2	521011.Mpal_0942	1.907e-91	317.0	COG1232@1|root,arCOG01522@2157|Archaea,2XY37@28890|Euryarchaeota	28890|Euryarchaeota	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
ZZS2_k127_3690491_9	944560.HMPREF9058_0491	5.85e-15	88.0	COG0477@1|root,COG2814@2|Bacteria,2IAX5@201174|Actinobacteria,4D316@85005|Actinomycetales	201174|Actinobacteria	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS2_k127_3690491_12	768671.ThimaDRAFT_0758	1.038e-05	58.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
ZZS2_k127_3690491_3	1123257.AUFV01000003_gene829	9.219e-69	244.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1X3ZV@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
ZZS2_k127_3690491_13	483219.LILAB_30070	0.0002202	54.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_373008_1	110662.Syncc9605_0013	1.872e-108	378.0	COG0165@1|root,COG0165@2|Bacteria,1G1IS@1117|Cyanobacteria,1GZ1P@1129|Synechococcus	1117|Cyanobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argH	ASL_C2,Lyase_1
ZZS2_k127_373008_0	3641.EOY22446	2.31e-146	491.0	COG0137@1|root,KOG1706@2759|Eukaryota,37QUX@33090|Viridiplantae,3G8Y6@35493|Streptophyta	35493|Streptophyta	E	argininosuccinate synthase	-	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
ZZS2_k127_373008_2	671143.DAMO_0075	1.831e-87	315.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS2_k127_373008_3	1303518.CCALI_02163	3.775e-85	299.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204,iHN637.CLJU_RS10560	Aminotran_3
ZZS2_k127_373008_7	204669.Acid345_4160	2.627e-45	174.0	COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria,2JIE8@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
ZZS2_k127_373008_4	667014.Thein_1375	5.078e-85	292.0	COG0002@1|root,COG0002@2|Bacteria,2GHK1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS2_k127_373008_8	106370.Francci3_3170	5.736e-22	105.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4ESWE@85013|Frankiales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
ZZS2_k127_373008_6	502025.Hoch_4693	6.386e-56	214.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,42UMA@68525|delta/epsilon subdivisions,2WRJM@28221|Deltaproteobacteria,2Z34V@29|Myxococcales	28221|Deltaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
ZZS2_k127_373008_5	1121957.ATVL01000014_gene1459	4.532e-60	223.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3734741_0	234267.Acid_7735	1.188e-139	451.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
ZZS2_k127_3734741_3	1123508.JH636441_gene3024	1.623e-20	99.0	2EKVR@1|root,33EJ9@2|Bacteria,2J47Y@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3734741_1	1379270.AUXF01000006_gene150	1.21e-44	171.0	2DEWU@1|root,2ZPJP@2|Bacteria,1ZUFA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3734741_4	102125.Xen7305DRAFT_00050770	6.636e-08	55.0	29WKM@1|root,30I78@2|Bacteria,1GG4U@1117|Cyanobacteria,3VN6N@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3743029_0	1122137.AQXF01000004_gene1464	5.533e-32	132.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U2RG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_3743029_4	706587.Desti_2358	5.323e-12	76.0	2DBXQ@1|root,2ZBQY@2|Bacteria,1PAVT@1224|Proteobacteria,433I7@68525|delta/epsilon subdivisions,2WX9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3743029_1	575540.Isop_3372	4.998e-24	109.0	COG4634@1|root,COG4634@2|Bacteria,2J4DQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3743029_2	575540.Isop_3373	1.212e-23	104.0	COG2442@1|root,COG2442@2|Bacteria,2J4DY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
ZZS2_k127_3743029_5	379066.GAU_0527	2.748e-10	70.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3743029_3	595460.RRSWK_00820	4.798e-17	87.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_3743029_6	1123508.JH636442_gene4121	1.825e-05	57.0	COG4886@1|root,COG4886@2|Bacteria,2J0H6@203682|Planctomycetes	203682|Planctomycetes	K	Leucine-rich repeats, outliers	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
ZZS2_k127_37736_7	237368.SCABRO_01429	1.08e-34	141.0	COG0265@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1716@2|Bacteria,2J23K@203682|Planctomycetes	203682|Planctomycetes	OT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
ZZS2_k127_37736_8	863365.XHC_2248	5.778e-34	146.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1X4CZ@135614|Xanthomonadales	135614|Xanthomonadales	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
ZZS2_k127_37736_6	448385.sce8626	3.394e-38	162.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2YWRT@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
ZZS2_k127_37736_3	1183438.GKIL_1590	1.366e-167	563.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
ZZS2_k127_37736_10	1380391.JIAS01000012_gene4563	0.0001065	48.0	COG0633@1|root,COG2114@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,1N5XC@1224|Proteobacteria,2TRGX@28211|Alphaproteobacteria,2JR7W@204441|Rhodospirillales	204441|Rhodospirillales	CT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Guanylate_cyc
ZZS2_k127_37736_5	446470.Snas_1211	6.041e-40	157.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria	2|Bacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_25,RrnaAD
ZZS2_k127_37736_0	1122919.KB905588_gene4037	8.088e-303	953.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26QCH@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
ZZS2_k127_37736_4	926550.CLDAP_00570	5.063e-129	434.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
ZZS2_k127_37736_2	886293.Sinac_0956	2.856e-184	616.0	COG2010@1|root,COG2010@2|Bacteria,2IWY5@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PA14,PSCyt1,PSCyt2,PSD1
ZZS2_k127_37736_1	886293.Sinac_0955	5.207e-232	725.0	COG4102@1|root,COG4102@2|Bacteria,2IXAC@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_37736_9	1254432.SCE1572_07780	1.34e-06	55.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ZZS2_k127_3783097_9	1442599.JAAN01000014_gene3568	1.249e-08	57.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1X4BQ@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_3783097_5	768671.ThimaDRAFT_0245	8.08e-42	176.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RZ20@1236|Gammaproteobacteria,1WY9D@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
ZZS2_k127_3783097_7	319795.Dgeo_2147	3.227e-13	83.0	COG0784@1|root,COG0784@2|Bacteria,1WMM2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_3783097_2	5022.CBX90919	1.266e-87	291.0	COG0652@1|root,KOG0865@2759|Eukaryota,38FFS@33154|Opisthokonta,3P1SD@4751|Fungi,3QSKZ@4890|Ascomycota,2094R@147541|Dothideomycetes,4KGPA@92860|Pleosporales	4751|Fungi	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K09565	ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS2_k127_3783097_10	521011.Mpal_2732	4.077e-06	60.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
ZZS2_k127_3783097_6	272134.KB731324_gene1337	6.198e-30	126.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
ZZS2_k127_3783097_0	1192124.LIG30_1791	8.125e-182	575.0	COG0604@1|root,COG0604@2|Bacteria,1R8NX@1224|Proteobacteria,2W0KY@28216|Betaproteobacteria,1K4PK@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
ZZS2_k127_3783097_4	1242864.D187_005897	1.531e-44	176.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42P93@68525|delta/epsilon subdivisions,2WUZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
ZZS2_k127_3783097_3	1123242.JH636435_gene941	1.936e-69	241.0	COG4149@1|root,COG4149@2|Bacteria,2J01Z@203682|Planctomycetes	203682|Planctomycetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
ZZS2_k127_3783097_1	290397.Adeh_0998	2.849e-94	332.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,43AKP@68525|delta/epsilon subdivisions,2X60N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
ZZS2_k127_3795838_1	452637.Oter_2327	3.745e-187	614.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3795838_2	1089548.KI783301_gene2142	1.296e-101	352.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3WFCF@539002|Bacillales incertae sedis	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS2_k127_3795838_3	709991.Odosp_0894	5.035e-20	101.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
ZZS2_k127_3795838_5	391596.PBAL39_13205	5.068e-05	54.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1ISZ1@117747|Sphingobacteriia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
ZZS2_k127_3795838_0	344747.PM8797T_19480	1.581e-239	780.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrom_C,GSDH,HEAT_2
ZZS2_k127_3814206_4	1123508.JH636440_gene2651	2.786e-05	57.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS2_k127_3814206_3	1278073.MYSTI_05853	6.001e-08	66.0	COG0457@1|root,COG0457@2|Bacteria	1278073.MYSTI_05853|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3814206_5	856793.MICA_1252	0.0001283	53.0	COG2253@1|root,COG2253@2|Bacteria,1MWST@1224|Proteobacteria,2TSSG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
ZZS2_k127_3814206_0	502025.Hoch_5309	6.16e-166	554.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
ZZS2_k127_3814206_2	349124.Hhal_0708	6.556e-12	77.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria	1224|Proteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
ZZS2_k127_3814206_1	314230.DSM3645_13810	6.529e-14	79.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
ZZS2_k127_3963450_7	757424.Hsero_3477	3.408e-14	76.0	2FK9B@1|root,34BWZ@2|Bacteria,1P202@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3963450_8	382464.ABSI01000008_gene4040	1.186e-08	66.0	2DPS8@1|root,3335W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_3963450_9	1122603.ATVI01000007_gene1437	6.753e-07	60.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1X6XU@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein, required for colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
ZZS2_k127_3963450_0	391625.PPSIR1_38616	1.322e-267	831.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
ZZS2_k127_3963450_5	530564.Psta_3303	3.34e-62	237.0	COG5002@1|root,COG5002@2|Bacteria,2IY8P@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
ZZS2_k127_3963450_4	706587.Desti_5065	2.473e-68	243.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_3963450_6	717231.Flexsi_1646	1.307e-50	207.0	COG0265@1|root,COG0265@2|Bacteria,2GERQ@200930|Deferribacteres	200930|Deferribacteres	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_3963450_3	240016.ABIZ01000001_gene3189	1.311e-90	325.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
ZZS2_k127_3963450_1	1254432.SCE1572_24275	1.655e-158	513.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,42YKP@68525|delta/epsilon subdivisions,2WUQ9@28221|Deltaproteobacteria,2YWFW@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	araG	-	3.6.3.17	ko:K02056,ko:K05776,ko:K10441,ko:K10539,ko:K10542,ko:K10545,ko:K10548	ko02010,map02010	M00189,M00212,M00213,M00214,M00215,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2,3.A.1.2.3,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
ZZS2_k127_3963450_2	344747.PM8797T_24606	5.072e-96	323.0	COG1879@1|root,COG1879@2|Bacteria,2IZC9@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system, periplasmic	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS2_k127_3970867_3	429009.Adeg_0526	2.9e-94	325.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ZZS2_k127_3970867_8	1121017.AUFG01000008_gene1344	8.905e-26	123.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4FE73@85021|Intrasporangiaceae	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
ZZS2_k127_3970867_6	1123274.KB899407_gene236	1.075e-44	169.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
ZZS2_k127_3970867_4	235909.GK1975	1.647e-92	320.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HBX5@91061|Bacilli,1WFG6@129337|Geobacillus	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS2_k127_3970867_5	1210884.HG799465_gene12185	6.966e-63	227.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
ZZS2_k127_3970867_7	439235.Dalk_3476	5.675e-28	133.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42T39@68525|delta/epsilon subdivisions,2WPHT@28221|Deltaproteobacteria,2MPRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_3970867_2	452637.Oter_1389	7.328e-106	381.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_3970867_0	1260251.SPISAL_07325	1.93e-240	756.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1X2EG@135613|Chromatiales	135613|Chromatiales	P	PUA-like domain	-	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
ZZS2_k127_3970867_1	102232.GLO73106DRAFT_00023870	1.043e-112	376.0	COG0457@1|root,COG0859@1|root,COG1216@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,COG1216@2|Bacteria,1G193@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,Methyltransf_21,TPR_1,TPR_11,TPR_14,TPR_16,TPR_17,TPR_2,TPR_8
ZZS2_k127_3970867_9	493475.GARC_4265	1.805e-18	93.0	COG2931@1|root,COG2982@1|root,COG4733@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG4733@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
ZZS2_k127_4020163_8	861299.J421_2903	4.537e-41	172.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
ZZS2_k127_4020163_7	1056816.JAFQ01000004_gene3839	2.531e-47	183.0	COG5464@1|root,COG5464@2|Bacteria,2II2Z@201174|Actinobacteria,4FVX9@85025|Nocardiaceae	201174|Actinobacteria	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
ZZS2_k127_4020163_9	861299.J421_4225	7.514e-38	157.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
ZZS2_k127_4020163_1	1379698.RBG1_1C00001G0785	3.466e-133	440.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
ZZS2_k127_4020163_4	716544.wcw_1275	1.232e-118	395.0	COG0183@1|root,COG0183@2|Bacteria,2JFS7@204428|Chlamydiae	204428|Chlamydiae	I	Thiolase, C-terminal domain	fadI	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_4020163_2	1033802.SSPSH_001174	1.899e-129	454.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
ZZS2_k127_4020163_14	2423.NA23_0207190	3.676e-11	75.0	COG1073@1|root,COG1073@2|Bacteria,2GC7C@200918|Thermotogae	200918|Thermotogae	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
ZZS2_k127_4020163_11	204669.Acid345_1382	4.881e-36	158.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4020163_17	526222.Desal_2632	4.278e-05	53.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WQUM@28221|Deltaproteobacteria,2MB34@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
ZZS2_k127_4020163_13	1210884.HG799466_gene12298	7.516e-12	77.0	COG2974@1|root,COG2974@2|Bacteria,2IX80@203682|Planctomycetes	203682|Planctomycetes	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4020163_12	1254432.SCE1572_44685	2.503e-17	88.0	COG0433@1|root,COG0433@2|Bacteria,1R2Z2@1224|Proteobacteria,43DI9@68525|delta/epsilon subdivisions,2X8PX@28221|Deltaproteobacteria,2Z21R@29|Myxococcales	2|Bacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
ZZS2_k127_4020163_6	1254432.SCE1572_44680	2.457e-47	177.0	COG2253@1|root,COG2253@2|Bacteria,1NQ5D@1224|Proteobacteria,42UBR@68525|delta/epsilon subdivisions,2WTDZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
ZZS2_k127_4020163_5	378806.STAUR_7782	5.191e-63	228.0	COG3382@1|root,COG3382@2|Bacteria,1N6A7@1224|Proteobacteria,4337M@68525|delta/epsilon subdivisions,2WXR0@28221|Deltaproteobacteria,2YUZ2@29|Myxococcales	28221|Deltaproteobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
ZZS2_k127_4020163_15	1382303.JPOM01000001_gene1764	3.456e-10	68.0	COG1595@1|root,COG1595@2|Bacteria,1RD9G@1224|Proteobacteria,2U92K@28211|Alphaproteobacteria,2KGJR@204458|Caulobacterales	204458|Caulobacterales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_4020163_0	518766.Rmar_0906	1.399e-152	504.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes	976|Bacteroidetes	J	Peptidase m28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_4020163_16	1151292.QEW_2798	1.29e-07	61.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25RN1@186804|Peptostreptococcaceae	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
ZZS2_k127_4020163_10	1148.1652970	1.165e-36	146.0	COG1598@1|root,COG1724@1|root,COG1598@2|Bacteria,COG1724@2|Bacteria,1G985@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
ZZS2_k127_4020163_3	335543.Sfum_0092	5.409e-120	396.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42P92@68525|delta/epsilon subdivisions,2WKXT@28221|Deltaproteobacteria,2MS0R@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
ZZS2_k127_4028063_1	1869.MB27_25175	1.652e-26	118.0	COG2949@1|root,COG2949@2|Bacteria,2GWVK@201174|Actinobacteria,4DCPR@85008|Micromonosporales	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
ZZS2_k127_4028063_2	1173025.GEI7407_2644	6.556e-23	116.0	COG2251@1|root,COG2251@2|Bacteria,1G03D@1117|Cyanobacteria,1H8MQ@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM RecB family nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,RNase_H_2
ZZS2_k127_4028063_0	448385.sce3157	1.301e-207	668.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	GATase,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS2_k127_4028063_3	1121405.dsmv_1230	3.727e-07	63.0	COG3746@1|root,COG3746@2|Bacteria,1QXPF@1224|Proteobacteria,42TW0@68525|delta/epsilon subdivisions,2WQ4G@28221|Deltaproteobacteria,2MNVB@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
ZZS2_k127_4075976_0	1125863.JAFN01000001_gene1578	2.48e-163	522.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
ZZS2_k127_4075976_3	382464.ABSI01000023_gene536	1.261e-33	140.0	COG0629@1|root,COG0629@2|Bacteria,46VGA@74201|Verrucomicrobia,2IUK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
ZZS2_k127_4075976_4	290397.Adeh_2361	0.0003772	48.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
ZZS2_k127_4075976_2	404589.Anae109_4214	1.283e-56	209.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
ZZS2_k127_4075976_1	1382356.JQMP01000004_gene450	2.45e-101	341.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi,27XG3@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS2_k127_4117352_1	661478.OP10G_1219	9.772e-131	424.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS2_k127_4117352_3	886293.Sinac_4872	6.471e-41	165.0	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_4117352_2	1469557.JSWF01000012_gene1222	3.029e-56	211.0	COG4927@1|root,COG4927@2|Bacteria,4NGJT@976|Bacteroidetes,1I8IC@117743|Flavobacteriia	976|Bacteroidetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
ZZS2_k127_4117352_0	575540.Isop_1882	1.346e-195	657.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8,WD40
ZZS2_k127_4140878_3	649831.L083_1665	5.015e-68	240.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4DB5S@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_4140878_9	1183438.GKIL_1150	4.189e-08	68.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,VCBS
ZZS2_k127_4140878_1	1192034.CAP_6894	2.47e-156	507.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUHS@29|Myxococcales	28221|Deltaproteobacteria	D	5' nucleotidase family	surE2	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
ZZS2_k127_4140878_6	391625.PPSIR1_39800	1.054e-20	101.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_4140878_7	313624.NSP_29150	2.593e-15	79.0	COG4185@1|root,COG4185@2|Bacteria,1G56J@1117|Cyanobacteria,1HR70@1161|Nostocales	1117|Cyanobacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
ZZS2_k127_4140878_8	1236514.BAKL01000030_gene2623	2.478e-09	70.0	COG0526@1|root,COG0526@2|Bacteria,4NRZT@976|Bacteroidetes,2FN4G@200643|Bacteroidia,4AN4K@815|Bacteroidaceae	976|Bacteroidetes	CO	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
ZZS2_k127_4140878_10	344747.PM8797T_24886	0.000115	54.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
ZZS2_k127_4140878_5	1122137.AQXF01000005_gene1008	1.107e-21	106.0	COG2931@1|root,COG2931@2|Bacteria,1NNT4@1224|Proteobacteria,2UKB7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_4140878_4	314230.DSM3645_04470	6.228e-23	113.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS2_k127_4140878_0	330214.NIDE2073	6.214e-169	564.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
ZZS2_k127_4140878_2	237368.SCABRO_03725	1.305e-147	478.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
ZZS2_k127_4211442_4	1232410.KI421413_gene838	8.858e-48	179.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,43UP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
ZZS2_k127_4211442_7	1396141.BATP01000030_gene3755	4.414e-24	116.0	COG2127@1|root,COG2127@2|Bacteria,46T8N@74201|Verrucomicrobia,2IUSR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	-	-	-	-	-	-	-	-	-	ClpS
ZZS2_k127_4211442_1	760192.Halhy_2059	3.993e-194	661.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IW7V@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
ZZS2_k127_4211442_0	575540.Isop_1644	6.661e-225	737.0	COG0265@1|root,COG3266@1|root,COG4447@1|root,COG0265@2|Bacteria,COG3266@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4,3.4.21.107	ko:K01179,ko:K04771	ko00500,ko01100,ko01503,ko02020,map00500,map01100,map01503,map02020	M00728	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	PDZ_2,Sortilin-Vps10,Trypsin_2
ZZS2_k127_4211442_10	1206743.BAGM01000049_gene1214	0.0002667	54.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria,4FV1Y@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
ZZS2_k127_4211442_9	1449353.JQMQ01000005_gene4022	2.423e-12	81.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2IBIG@201174|Actinobacteria,2NH9X@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
ZZS2_k127_4211442_5	266117.Rxyl_0730	1.029e-38	168.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CU1S@84995|Rubrobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_4211442_8	1343740.M271_24590	1.79e-15	91.0	COG0745@1|root,COG0745@2|Bacteria,2GNFH@201174|Actinobacteria	201174|Actinobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	prrA	GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944	-	ko:K07671	ko02020,map02020	M00462	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_4211442_2	573413.Spirs_2154	1.387e-66	252.0	COG0215@1|root,COG0215@2|Bacteria,2J618@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
ZZS2_k127_4211442_3	710696.Intca_0096	1.995e-59	222.0	COG0189@1|root,COG0189@2|Bacteria,2I75I@201174|Actinobacteria,4FEMX@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
ZZS2_k127_4211442_6	1297742.A176_00058	2.516e-28	128.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
ZZS2_k127_4211442_11	1249975.JQLP01000005_gene515	0.0002965	53.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia,2P5I4@244698|Gillisia	976|Bacteroidetes	T	Universal stress protein family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS2_k127_4254824_16	1054213.HMPREF9946_03239	3.452e-14	75.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VETM@28211|Alphaproteobacteria,2JYMX@204441|Rhodospirillales	204441|Rhodospirillales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS2_k127_4254824_14	1123242.JH636434_gene5299	3.526e-23	113.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS2_k127_4254824_12	1144275.COCOR_03311	5.298e-34	141.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
ZZS2_k127_4254824_3	1172188.KB911820_gene2097	9.859e-111	370.0	COG0189@1|root,COG0189@2|Bacteria,2I75I@201174|Actinobacteria,4FEMX@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
ZZS2_k127_4254824_9	391625.PPSIR1_11120	1.646e-44	166.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
ZZS2_k127_4254824_13	1336243.JAEA01000002_gene2509	6.496e-24	117.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,1JTYK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
ZZS2_k127_4254824_5	1192034.CAP_4095	1.743e-89	314.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
ZZS2_k127_4254824_18	84531.JMTZ01000083_gene4302	8.184e-05	52.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_4254824_10	1284352.AOIG01000013_gene3550	1.63e-39	165.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
ZZS2_k127_4254824_1	903818.KI912268_gene871	8.828e-137	447.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
ZZS2_k127_4254824_19	429009.Adeg_0325	0.0001423	53.0	COG1082@1|root,COG1082@2|Bacteria,1V1Y1@1239|Firmicutes,24Y9G@186801|Clostridia,42HWD@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_4254824_8	404589.Anae109_1099	9.078e-58	215.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
ZZS2_k127_4254824_11	1090320.KB900605_gene1403	4.514e-34	141.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,2K24Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase,Phos_pyr_kin
ZZS2_k127_4254824_2	28072.Nos7524_0557	1.593e-122	415.0	COG1022@1|root,COG1022@2|Bacteria,1G1QY@1117|Cyanobacteria,1HK9K@1161|Nostocales	1117|Cyanobacteria	I	Long-chain acyl-CoA synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
ZZS2_k127_4254824_7	404380.Gbem_2646	1.194e-66	247.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,43U4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
ZZS2_k127_4254824_0	338966.Ppro_0642	0.0	1127.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS2_k127_4254824_17	338969.Rfer_0248	6.826e-07	62.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2WC2E@28216|Betaproteobacteria,4AIRV@80864|Comamonadaceae	28216|Betaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
ZZS2_k127_4254824_15	1396418.BATQ01000185_gene2102	9.79e-22	109.0	2AX2R@1|root,31P12@2|Bacteria,46WJT@74201|Verrucomicrobia,2IWCE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Family of unknown function (DUF5329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5329
ZZS2_k127_4254824_4	314230.DSM3645_18356	1.783e-108	367.0	COG1680@1|root,COG1680@2|Bacteria,2IZXU@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_4254824_6	1499967.BAYZ01000080_gene938	7.107e-67	241.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
ZZS2_k127_4372403_15	521674.Plim_2872	4.515e-43	180.0	2AU2S@1|root,31JP5@2|Bacteria,2IZEE@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_4372403_6	391625.PPSIR1_25771	3.948e-92	312.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales	28221|Deltaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
ZZS2_k127_4372403_19	483219.LILAB_31250	1.809e-26	117.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4372403_3	584708.Apau_0839	9.723e-140	458.0	COG1220@1|root,COG1220@2|Bacteria,3T9T7@508458|Synergistetes	508458|Synergistetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
ZZS2_k127_4372403_27	595460.RRSWK_02898	0.0004013	49.0	COG2013@1|root,COG2013@2|Bacteria,2IXEA@203682|Planctomycetes	203682|Planctomycetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
ZZS2_k127_4372403_1	443143.GM18_0129	6.17e-248	786.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
ZZS2_k127_4372403_22	1123508.JH636444_gene5476	1.044e-12	73.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
ZZS2_k127_4372403_4	338963.Pcar_0553	8.91e-133	452.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,43S4V@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	GIY-YIG type nucleases (URI domain)	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
ZZS2_k127_4372403_2	886293.Sinac_0575	2.597e-164	561.0	COG2268@1|root,COG2268@2|Bacteria,2IYIX@203682|Planctomycetes	203682|Planctomycetes	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
ZZS2_k127_4372403_21	411467.BACCAP_02095	1.758e-16	87.0	29F7N@1|root,3025B@2|Bacteria,1V7G9@1239|Firmicutes,24KI2@186801|Clostridia,269Q9@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
ZZS2_k127_4372403_11	338963.Pcar_2212	2.947e-48	190.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria,43S87@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
ZZS2_k127_4372403_7	857293.CAAU_0170	1.359e-80	289.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,36DF4@31979|Clostridiaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS2_k127_4372403_14	1235796.C815_00890	1.674e-43	172.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes	1239|Firmicutes	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ZZS2_k127_4372403_5	880073.Calab_0899	9.99e-125	419.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,Pribosyltran,RQC,RecQ_Zn_bind
ZZS2_k127_4372403_8	1449357.JQLK01000001_gene1667	2.063e-63	240.0	2A1UA@1|root,30Q39@2|Bacteria,1WM6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4372403_10	886293.Sinac_7396	1.962e-57	229.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_4372403_0	1499967.BAYZ01000001_gene5910	0.0	1196.0	COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
ZZS2_k127_4372403_12	251229.Chro_1292	9.5e-45	169.0	COG3124@1|root,COG3124@2|Bacteria,1GKY3@1117|Cyanobacteria,3VMTC@52604|Pleurocapsales	1117|Cyanobacteria	S	Pfam:DUF479	-	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
ZZS2_k127_4372403_9	649764.HMPREF0762_00253	1.862e-58	217.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CVQQ@84998|Coriobacteriia	84998|Coriobacteriia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
ZZS2_k127_4372403_25	1227349.C170_16680	2.336e-08	66.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
ZZS2_k127_4372403_16	247490.KSU1_C0304	1.386e-38	158.0	COG1039@1|root,COG1039@2|Bacteria,2IZ83@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4372403_26	1227360.C176_07027	3.009e-07	57.0	COG4565@1|root,COG4565@2|Bacteria,1V49R@1239|Firmicutes,4HHD4@91061|Bacilli,26FI0@186818|Planococcaceae	91061|Bacilli	T	cheY-homologous receiver domain	dctR	-	-	ko:K02475,ko:K11692	ko02020,map02020	M00489	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FaeA,HTH_11,HTH_DeoR,HTH_IclR,Response_reg
ZZS2_k127_4372403_13	1220534.B655_2056	8.347e-44	181.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,23NMT@183925|Methanobacteria	183925|Methanobacteria	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
ZZS2_k127_4372403_20	316274.Haur_4095	2.288e-26	126.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
ZZS2_k127_4372403_23	661478.OP10G_4428	1.341e-12	81.0	COG0457@1|root,COG0457@2|Bacteria	661478.OP10G_4428|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4372403_18	575540.Isop_0858	6.193e-27	117.0	COG0764@1|root,COG0764@2|Bacteria,2IZNA@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
ZZS2_k127_4372403_24	1041146.ATZB01000006_gene2423	2.665e-11	64.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,4B752@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
ZZS2_k127_4395077_5	1278073.MYSTI_06118	6.277e-71	252.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
ZZS2_k127_4395077_10	1396141.BATP01000022_gene258	1.909e-21	103.0	COG2836@1|root,COG2836@2|Bacteria,46VBD@74201|Verrucomicrobia,2IUEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
ZZS2_k127_4395077_4	502025.Hoch_5307	1.249e-77	267.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,42T9X@68525|delta/epsilon subdivisions,2WP59@28221|Deltaproteobacteria,2YWRF@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_4395077_14	1144275.COCOR_02312	4.184e-10	72.0	COG0784@1|root,COG0784@2|Bacteria,1QX9E@1224|Proteobacteria,43C2K@68525|delta/epsilon subdivisions,2X7D6@28221|Deltaproteobacteria,2YWB6@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
ZZS2_k127_4395077_2	234267.Acid_7437	2.647e-95	341.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,3Y79C@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
ZZS2_k127_4395077_3	448385.sce2438	1.258e-84	291.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42UHT@68525|delta/epsilon subdivisions,2WR0M@28221|Deltaproteobacteria,2YUP9@29|Myxococcales	28221|Deltaproteobacteria	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
ZZS2_k127_4395077_0	1279009.ADICEAN_02534	2.152e-154	498.0	COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,47N3T@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome bd terminal oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
ZZS2_k127_4395077_17	1391646.AVSU01000063_gene3368	2.959e-07	56.0	2EJ8N@1|root,33CZU@2|Bacteria,1VPE9@1239|Firmicutes,24UEF@186801|Clostridia	186801|Clostridia	S	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
ZZS2_k127_4395077_16	1391646.AVSU01000063_gene3369	1.363e-08	67.0	COG2172@1|root,COG2172@2|Bacteria,1VCM4@1239|Firmicutes	1239|Firmicutes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4395077_6	1173024.KI912149_gene5149	2.807e-67	237.0	COG0500@1|root,COG2226@2|Bacteria,1G24H@1117|Cyanobacteria,1JHP9@1189|Stigonemataceae	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_4395077_9	1173024.KI912148_gene2732	3.393e-27	126.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
ZZS2_k127_4395077_12	1173027.Mic7113_0265	2.401e-14	86.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_4395077_8	1123371.ATXH01000003_gene1927	2.537e-32	141.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GGDEF
ZZS2_k127_4395077_7	1528106.JRJE01000027_gene434	3.652e-54	216.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2TVZ5@28211|Alphaproteobacteria,2JUHI@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
ZZS2_k127_4395077_11	1279009.ADICEAN_00831	3.943e-17	90.0	COG3527@1|root,COG3527@2|Bacteria,4NKWJ@976|Bacteroidetes	976|Bacteroidetes	Q	Alpha-acetolactate decarboxylase	-	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
ZZS2_k127_4395077_13	696747.NIES39_L00750	7.239e-12	79.0	COG2755@1|root,COG2755@2|Bacteria,1G2XP@1117|Cyanobacteria,1H81W@1150|Oscillatoriales	1117|Cyanobacteria	E	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
ZZS2_k127_4395077_15	1207063.P24_16572	7.829e-09	64.0	COG1051@1|root,COG1051@2|Bacteria,1N8ZD@1224|Proteobacteria,2VC5V@28211|Alphaproteobacteria,2JXY9@204441|Rhodospirillales	204441|Rhodospirillales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS2_k127_4395077_1	1254432.SCE1572_07650	2.168e-143	466.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS2_k127_4454222_14	632292.Calhy_0896	2.667e-08	63.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_4454222_11	243090.RB3287	2.592e-36	160.0	COG0767@1|root,COG1127@1|root,COG0767@2|Bacteria,COG1127@2|Bacteria	2|Bacteria	Q	ATPase activity	ttg2A	-	-	ko:K02065,ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,MlaE
ZZS2_k127_4454222_13	675814.VIC_003965	2.719e-12	81.0	COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XTE9@135623|Vibrionales	135623|Vibrionales	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
ZZS2_k127_4454222_0	1121920.AUAU01000007_gene519	5.693e-215	694.0	COG0187@1|root,COG0187@2|Bacteria,3Y369@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
ZZS2_k127_4454222_15	575540.Isop_1649	1.409e-05	51.0	COG5512@1|root,COG5512@2|Bacteria,2J185@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
ZZS2_k127_4454222_7	1142394.PSMK_03840	1.169e-52	201.0	COG0592@1|root,COG0592@2|Bacteria,2IY9S@203682|Planctomycetes	203682|Planctomycetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
ZZS2_k127_4454222_3	521098.Aaci_0001	1.819e-106	365.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,277VV@186823|Alicyclobacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
ZZS2_k127_4454222_9	472759.Nhal_1930	7.215e-46	182.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1WWHG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_4454222_2	926566.Terro_4115	2.037e-111	370.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_4454222_6	656519.Halsa_2383	4.215e-62	224.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WA7J@53433|Halanaerobiales	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
ZZS2_k127_4454222_10	670487.Ocepr_1524	2.448e-38	165.0	COG2120@1|root,COG2120@2|Bacteria,1WIUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
ZZS2_k127_4454222_8	1191523.MROS_1914	6.987e-50	197.0	COG4365@1|root,COG4365@2|Bacteria	2|Bacteria	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
ZZS2_k127_4454222_5	1304880.JAGB01000001_gene577	4.479e-64	229.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
ZZS2_k127_4454222_4	41431.PCC8801_2896	1.523e-94	336.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,3KGN0@43988|Cyanothece	1117|Cyanobacteria	C	PFAM alanine dehydrogenase PNT domain protein	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
ZZS2_k127_4454222_12	1121878.AUGL01000019_gene1591	8.094e-21	108.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3288 NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
ZZS2_k127_4454222_1	1288494.EBAPG3_22020	3.686e-123	410.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,372C8@32003|Nitrosomonadales	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
ZZS2_k127_4484137_1	1396141.BATP01000032_gene4278	1.083e-84	289.0	COG0515@1|root,COG0515@2|Bacteria,46TQZ@74201|Verrucomicrobia,2IV7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_4484137_4	497964.CfE428DRAFT_4864	1.437e-47	181.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4484137_3	118168.MC7420_1580	1e-63	233.0	COG1680@1|root,COG1680@2|Bacteria,1G7C0@1117|Cyanobacteria,1HD9W@1150|Oscillatoriales	1117|Cyanobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
ZZS2_k127_4484137_6	886293.Sinac_6333	3.093e-18	101.0	COG1807@1|root,COG1807@2|Bacteria,2J2F6@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4484137_2	521674.Plim_4051	3.181e-76	287.0	COG1216@1|root,COG1216@2|Bacteria,2IYBZ@203682|Planctomycetes	203682|Planctomycetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_4484137_0	554065.XP_005850866.1	1.974e-100	349.0	COG0042@1|root,KOG2333@2759|Eukaryota,37YV0@33090|Viridiplantae,34K64@3041|Chlorophyta	3041|Chlorophyta	J	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	-	-	1.3.1.89	ko:K05544	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
ZZS2_k127_4484137_5	1121285.AUFK01000017_gene3224	1.263e-37	162.0	COG2304@1|root,COG2304@2|Bacteria,4NFNQ@976|Bacteroidetes,1I0RD@117743|Flavobacteriia,3ZNXU@59732|Chryseobacterium	976|Bacteroidetes	S	Von Willebrand factor A	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
ZZS2_k127_4489710_3	794903.OPIT5_07360	7.106e-142	453.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS2_k127_4489710_4	1121430.JMLG01000009_gene436	6.919e-130	425.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
ZZS2_k127_4489710_15	1177928.TH2_15477	6.56e-22	104.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,2JT4Q@204441|Rhodospirillales	204441|Rhodospirillales	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_6,Hydrolase_like,NTP_transferase
ZZS2_k127_4489710_14	644966.Tmar_0414	6.756e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4489710_2	861299.J421_5625	4.059e-151	511.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,GSDH
ZZS2_k127_4489710_1	525904.Tter_0987	7.242e-169	542.0	COG2115@1|root,COG2115@2|Bacteria,2NQDI@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
ZZS2_k127_4489710_5	452637.Oter_3559	5.584e-126	421.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
ZZS2_k127_4489710_7	382464.ABSI01000011_gene3187	7.763e-97	342.0	COG0815@1|root,COG0815@2|Bacteria,46W4F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4489710_11	443144.GM21_0084	6.487e-40	156.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
ZZS2_k127_4489710_19	383372.Rcas_1703	0.0005325	51.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_4489710_6	344747.PM8797T_20458	3.582e-110	373.0	COG0500@1|root,COG2226@2|Bacteria,2IXEP@203682|Planctomycetes	203682|Planctomycetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
ZZS2_k127_4489710_12	521674.Plim_1433	6.02e-37	152.0	28IP5@1|root,2Z8P7@2|Bacteria,2IX86@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
ZZS2_k127_4489710_10	1282362.AEAC466_05095	2.925e-41	167.0	COG1649@1|root,COG1649@2|Bacteria,1R6SN@1224|Proteobacteria,2U2S1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4489710_9	1210884.HG799467_gene13248	2.557e-69	261.0	COG1524@1|root,COG1524@2|Bacteria,2J1VF@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS2_k127_4489710_13	693986.MOC_1402	3.68e-23	109.0	COG4421@1|root,COG4421@2|Bacteria,1Q8C8@1224|Proteobacteria,2UK7Y@28211|Alphaproteobacteria,1JW44@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
ZZS2_k127_4489710_16	886293.Sinac_2657	3.535e-18	99.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
ZZS2_k127_4489710_0	1237149.C900_05550	9.787e-216	696.0	COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
ZZS2_k127_4489710_17	321327.CYA_2447	2.469e-05	57.0	COG0265@1|root,COG0265@2|Bacteria,1GQIF@1117|Cyanobacteria,1H1XG@1129|Synechococcus	1117|Cyanobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4489710_18	357808.RoseRS_2663	0.0002375	54.0	COG0457@1|root,COG0457@2|Bacteria	357808.RoseRS_2663|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4489710_8	321332.CYB_2017	1.101e-69	261.0	COG4636@1|root,COG4636@2|Bacteria,1G0VC@1117|Cyanobacteria,1H0CT@1129|Synechococcus	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_4497727_4	1120705.FG95_01696	2.819e-26	115.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2U38P@28211|Alphaproteobacteria,2K37I@204457|Sphingomonadales	204457|Sphingomonadales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
ZZS2_k127_4497727_3	266264.Rmet_4465	1.19e-46	178.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2VHHB@28216|Betaproteobacteria,1JZXJ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	czcR	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_4497727_1	596154.Alide2_1770	6.709e-87	305.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	arlS_1	-	2.7.13.3	ko:K02484,ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
ZZS2_k127_4497727_0	1163617.SCD_n02012	1.605e-138	461.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS2_k127_4497727_5	234267.Acid_6212	1.383e-18	101.0	COG0526@1|root,COG2834@1|root,COG0526@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF2092,LolA,Redoxin
ZZS2_k127_4497727_2	1535422.ND16A_3400	8.886e-48	194.0	COG0652@1|root,COG0652@2|Bacteria,1RBX1@1224|Proteobacteria,1SYJW@1236|Gammaproteobacteria,2Q6RR@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS2_k127_4497842_13	887062.HGR_14874	9.891e-19	98.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,2VID4@28216|Betaproteobacteria,4ABHI@80864|Comamonadaceae	28216|Betaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS2_k127_4497842_8	665942.HMPREF1022_00353	1.521e-39	161.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2M81K@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS2_k127_4497842_7	215803.DB30_3244	1.022e-40	171.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2YV85@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
ZZS2_k127_4497842_14	1089553.Tph_c02990	1.388e-17	87.0	COG4118@1|root,COG4118@2|Bacteria,1VHN9@1239|Firmicutes,24SB0@186801|Clostridia,42H49@68295|Thermoanaerobacterales	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
ZZS2_k127_4497842_9	562970.Btus_0893	2.336e-33	134.0	COG3744@1|root,COG3744@2|Bacteria,1V6HT@1239|Firmicutes	1239|Firmicutes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
ZZS2_k127_4497842_1	330214.NIDE1574	1.733e-114	383.0	COG2896@1|root,COG2896@2|Bacteria,3J0PB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
ZZS2_k127_4497842_15	189753.AXAS01000018_gene3222	3.281e-17	96.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,2TYMP@28211|Alphaproteobacteria,3JUCA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
ZZS2_k127_4497842_12	1382306.JNIM01000001_gene238	1.409e-23	109.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
ZZS2_k127_4497842_16	382464.ABSI01000005_gene1139	6.492e-12	76.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia	74201|Verrucomicrobia	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
ZZS2_k127_4497842_6	234267.Acid_4382	8.271e-56	212.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
ZZS2_k127_4497842_2	1123242.JH636438_gene5684	1.322e-80	283.0	COG1131@1|root,COG1131@2|Bacteria,2IYFJ@203682|Planctomycetes	203682|Planctomycetes	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_4497842_5	521674.Plim_0215	3.829e-56	217.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
ZZS2_k127_4497842_10	1279038.KB907352_gene2224	4.75e-33	132.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,2UJ8D@28211|Alphaproteobacteria,2JX8I@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
ZZS2_k127_4497842_11	671143.DAMO_2125	2.591e-28	120.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS2_k127_4497842_3	583355.Caka_0864	6.362e-75	260.0	COG1043@1|root,COG1043@2|Bacteria,46V8M@74201|Verrucomicrobia,3K837@414999|Opitutae	414999|Opitutae	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
ZZS2_k127_4497842_0	246197.MXAN_0341	1.598e-225	714.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
ZZS2_k127_4497842_4	235909.GK1597	1.991e-66	242.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1WFD8@129337|Geobacillus	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	yngJ	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_4497842_17	118168.MC7420_3740	4.114e-06	60.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_2,TPR_8
ZZS2_k127_4520035_10	866536.Belba_3195	0.0003457	48.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
ZZS2_k127_4520035_7	1128421.JAGA01000001_gene2335	6.48e-25	120.0	COG2244@1|root,COG2244@2|Bacteria,2NRKQ@2323|unclassified Bacteria	2|Bacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C,Wzy_C
ZZS2_k127_4520035_2	485914.Hmuk_0086	8.048e-92	332.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota,23SA4@183963|Halobacteria	183963|Halobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
ZZS2_k127_4520035_0	530564.Psta_1436	2.055e-124	429.0	COG0399@1|root,COG0399@2|Bacteria,2IYSK@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_4520035_3	1242864.D187_007363	1.933e-66	257.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4520035_1	530564.Psta_1051	4.898e-104	347.0	COG1611@1|root,COG1989@1|root,COG1611@2|Bacteria,COG1989@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
ZZS2_k127_4520035_4	1210884.HG799469_gene14146	9.86e-64	233.0	COG1082@1|root,COG1082@2|Bacteria,2IZ9I@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_4520035_5	1411685.U062_02366	7.361e-54	197.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1J53N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
ZZS2_k127_4520035_6	1519464.HY22_11275	1.234e-37	160.0	COG0577@1|root,COG0577@2|Bacteria,1FEN8@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_4520035_9	517418.Ctha_2414	3.748e-14	87.0	COG3495@1|root,COG3495@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
ZZS2_k127_4520035_8	1232410.KI421416_gene2665	1.236e-24	119.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria,43UEH@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5,sCache_3_2
ZZS2_k127_4525354_2	1210884.HG799467_gene13189	2.939e-30	122.0	COG0526@1|root,COG0526@2|Bacteria,2J12A@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
ZZS2_k127_4525354_3	1123242.JH636435_gene1455	7.669e-06	59.0	COG0265@1|root,COG0526@1|root,COG0265@2|Bacteria,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_4525354_1	1297742.A176_00707	6.539e-37	162.0	COG3359@1|root,COG3359@2|Bacteria,1R5KG@1224|Proteobacteria,437YC@68525|delta/epsilon subdivisions,2X388@28221|Deltaproteobacteria,2YUT6@29|Myxococcales	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
ZZS2_k127_4525354_0	717606.PaecuDRAFT_0767	2.992e-212	682.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,275MV@186822|Paenibacillaceae	91061|Bacilli	L	Domain of unknown function (DUF1998)	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
ZZS2_k127_4578524_1	483219.LILAB_27615	2.128e-112	371.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,2YYQ8@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
ZZS2_k127_4578524_2	665942.HMPREF1022_02955	1.532e-37	157.0	COG1212@1|root,COG1778@1|root,COG1212@2|Bacteria,COG1778@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2M9T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
ZZS2_k127_4578524_0	1123508.JH636439_gene1483	2.565e-217	687.0	COG0504@1|root,COG0504@2|Bacteria,2IXNE@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
ZZS2_k127_4612241_6	9031.ENSGALP00000042507	3.022e-13	80.0	KOG3544@1|root,KOG3544@2759|Eukaryota,39T88@33154|Opisthokonta,3BI6A@33208|Metazoa,3D2K5@33213|Bilateria,481M1@7711|Chordata,493FB@7742|Vertebrata,4GPA0@8782|Aves	33208|Metazoa	W	collagen	COL9A2	GO:0001501,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0005581,GO:0005593,GO:0005594,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007275,GO:0008150,GO:0009987,GO:0012505,GO:0016043,GO:0030020,GO:0030198,GO:0031974,GO:0032501,GO:0032502,GO:0032991,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048731,GO:0048856,GO:0070013,GO:0071840	-	ko:K08131	ko04151,ko04510,ko04512,ko04974,ko05165,map04151,map04510,map04512,map04974,map05165	-	-	-	ko00000,ko00001,ko00535,ko04516	-	-	-	Collagen
ZZS2_k127_4612241_0	411467.BACCAP_03545	0.0	1136.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,267JN@186813|unclassified Clostridiales	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS2_k127_4612241_1	314230.DSM3645_18081	4.084e-162	524.0	COG0015@1|root,COG0015@2|Bacteria,2IXU4@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
ZZS2_k127_4612241_8	404589.Anae109_1519	1.016e-06	60.0	COG5652@1|root,COG5652@2|Bacteria,1NIUW@1224|Proteobacteria	1224|Proteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
ZZS2_k127_4612241_9	1120949.KB903317_gene1574	9.022e-05	54.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
ZZS2_k127_4612241_2	300852.55772367	1.212e-59	218.0	COG0157@1|root,COG0157@2|Bacteria,1WIHZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
ZZS2_k127_4612241_7	349124.Hhal_0558	4.947e-13	76.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	ybaV	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.1.26.11	ko:K00784,ko:K02237,ko:K02238	ko03013,map03013	M00429	-	-	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.11.1,3.A.11.2	-	-	HHH_3
ZZS2_k127_4612241_3	913865.DOT_5345	6.607e-38	158.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,26151@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
ZZS2_k127_4612241_4	1121448.DGI_3448	1.626e-20	103.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2MBGZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
ZZS2_k127_4612241_5	1157640.AQWO01000007_gene3819	2.741e-16	86.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
ZZS2_k127_4613154_3	1123508.JH636444_gene5462	6.498e-127	413.0	COG0439@1|root,COG0439@2|Bacteria,2IWZV@203682|Planctomycetes	203682|Planctomycetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS2_k127_4613154_6	344747.PM8797T_07457	4.197e-89	316.0	COG0205@1|root,COG0205@2|Bacteria,2IYJ6@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ZZS2_k127_4613154_0	945713.IALB_1403	2.866e-144	475.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	rfbB	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_4613154_25	522306.CAP2UW1_4416	2.117e-09	64.0	COG4634@1|root,COG4634@2|Bacteria,1NHCH@1224|Proteobacteria,2W5NJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4613154_20	429009.Adeg_0280	9.754e-15	76.0	COG2442@1|root,COG2442@2|Bacteria,1VYG9@1239|Firmicutes,252G4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
ZZS2_k127_4613154_7	357808.RoseRS_4405	5.881e-85	297.0	COG1171@1|root,COG1171@2|Bacteria,2G6ME@200795|Chloroflexi,3776A@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS2_k127_4613154_2	661478.OP10G_0324	7.755e-144	468.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
ZZS2_k127_4613154_11	1379270.AUXF01000001_gene2805	1.394e-54	207.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
ZZS2_k127_4613154_26	1183438.GKIL_2416	1.831e-05	58.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS2_k127_4613154_14	1174684.EBMC1_00065	9.475e-31	132.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales	204457|Sphingomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
ZZS2_k127_4613154_4	215803.DB30_1638	6.411e-111	369.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
ZZS2_k127_4613154_12	1121440.AUMA01000020_gene1968	1.046e-52	195.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,2M8RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
ZZS2_k127_4613154_10	292415.Tbd_1455	7.48e-57	215.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,1KSK2@119069|Hydrogenophilales	119069|Hydrogenophilales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
ZZS2_k127_4613154_22	1210884.HG799462_gene8958	5.945e-10	71.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	PD40,Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4613154_8	1403819.BATR01000125_gene4450	1.765e-74	258.0	COG3000@1|root,COG3000@2|Bacteria,46ZIQ@74201|Verrucomicrobia,2IV2H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
ZZS2_k127_4613154_17	234267.Acid_5312	4.023e-25	113.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
ZZS2_k127_4613154_21	1273538.G159_01665	4.007e-11	71.0	COG5649@1|root,COG5649@2|Bacteria,1VF35@1239|Firmicutes,4HQN0@91061|Bacilli,26G7B@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS2_k127_4613154_18	391625.PPSIR1_07917	6.058e-22	107.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	arbV	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS2_k127_4613154_5	756272.Plabr_3149	1.373e-95	338.0	COG0644@1|root,COG0644@2|Bacteria,2J338@203682|Planctomycetes	2|Bacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,Trp_halogenase
ZZS2_k127_4613154_19	1538644.KO02_13870	4.486e-21	102.0	2EQN7@1|root,33I86@2|Bacteria,4NTSW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4613154_27	234267.Acid_4940	8.696e-05	56.0	COG1409@1|root,COG1657@1|root,COG4412@1|root,COG1409@2|Bacteria,COG1657@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K14647,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	CARDB,Peptidase_M30
ZZS2_k127_4613154_16	1396141.BATP01000051_gene3336	2.884e-26	119.0	2DMEF@1|root,32QYK@2|Bacteria,46W6R@74201|Verrucomicrobia,2IWHC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4613154_13	530564.Psta_1884	7.012e-41	162.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS2_k127_4613154_1	330214.NIDE0014	3.654e-144	469.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS2_k127_4613154_15	1452536.JARE01000068_gene3677	5.384e-29	124.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4FK4B@85023|Microbacteriaceae	201174|Actinobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
ZZS2_k127_4613154_23	1267535.KB906767_gene561	1.287e-09	59.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
ZZS2_k127_4613154_9	234267.Acid_1248	3.921e-65	233.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria	57723|Acidobacteria	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
ZZS2_k127_4644858_2	1192034.CAP_6879	7.317e-84	293.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2Z0CT@29|Myxococcales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
ZZS2_k127_4644858_4	1192034.CAP_6880	6.127e-77	264.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2Z0Q4@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS2_k127_4644858_7	1192034.CAP_6881	7.381e-28	132.0	COG1463@1|root,COG1463@2|Bacteria,1PV9I@1224|Proteobacteria,43EXS@68525|delta/epsilon subdivisions,2X225@28221|Deltaproteobacteria,2Z2A7@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
ZZS2_k127_4644858_10	1415754.JQMK01000005_gene1655	1.615e-11	76.0	COG4313@1|root,COG4313@2|Bacteria,1N1DR@1224|Proteobacteria,1SGI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
ZZS2_k127_4644858_3	886293.Sinac_2353	9.944e-80	282.0	COG1641@1|root,COG1641@2|Bacteria,2IXMJ@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
ZZS2_k127_4644858_5	237368.SCABRO_02284	1.539e-40	160.0	COG0231@1|root,COG0231@2|Bacteria,2IZ4X@203682|Planctomycetes	203682|Planctomycetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
ZZS2_k127_4644858_0	1123508.JH636439_gene1044	3.092e-118	389.0	COG1082@1|root,COG1082@2|Bacteria,2IWZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_4644858_1	648996.Theam_0589	2.553e-112	381.0	COG0436@1|root,COG0436@2|Bacteria,2G3PX@200783|Aquificae	200783|Aquificae	E	PFAM Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
ZZS2_k127_4644858_9	1279009.ADICEAN_01505	5.735e-16	87.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RS4@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_4644858_8	1162668.LFE_0393	8.623e-26	120.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
ZZS2_k127_4644858_6	160799.PBOR_30165	2.245e-38	149.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HE3C@91061|Bacilli,26Q8T@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the UbiD family	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
ZZS2_k127_4650685_11	243090.RB11955	1.101e-46	194.0	COG0515@1|root,COG0515@2|Bacteria,2IXP6@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_4650685_15	1219581.HMPREF1628_02080	2.183e-24	117.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4D3Q7@85005|Actinomycetales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS2_k127_4650685_7	8364.ENSXETP00000002366	2.459e-86	300.0	COG3340@1|root,2QR7X@2759|Eukaryota,39DGA@33154|Opisthokonta,3BC18@33208|Metazoa,3CWYN@33213|Bilateria,484TW@7711|Chordata,499CC@7742|Vertebrata	33208|Metazoa	E	Alpha-aspartyl dipeptidase-like	-	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
ZZS2_k127_4650685_0	1278073.MYSTI_03023	6.426e-159	534.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,43E81@68525|delta/epsilon subdivisions,2WZZ4@28221|Deltaproteobacteria,2YU4S@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS2_k127_4650685_6	886293.Sinac_7220	1.075e-90	323.0	COG0642@1|root,COG2205@2|Bacteria,2IZC4@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_4650685_9	530564.Psta_3872	4.091e-73	254.0	COG0745@1|root,COG0745@2|Bacteria,2IZ9J@203682|Planctomycetes	203682|Planctomycetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_4650685_10	1210884.HG799465_gene11872	2.233e-68	265.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
ZZS2_k127_4650685_8	886293.Sinac_1816	2.384e-78	291.0	COG2304@1|root,COG2304@2|Bacteria,2IY1T@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
ZZS2_k127_4650685_13	886293.Sinac_5578	2.44e-41	166.0	2BACU@1|root,323T9@2|Bacteria,2J05N@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4650685_14	886293.Sinac_5577	4.059e-39	159.0	COG1846@1|root,COG1846@2|Bacteria,2J085@203682|Planctomycetes	203682|Planctomycetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
ZZS2_k127_4650685_18	1385515.N791_00115	7.789e-06	49.0	COG2608@1|root,COG2608@2|Bacteria,1PUDI@1224|Proteobacteria,1SHDW@1236|Gammaproteobacteria,1X7FJ@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy-metal-associated domain	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
ZZS2_k127_4650685_4	861299.J421_3663	2.51e-97	334.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_4650685_1	575540.Isop_2477	9.753e-137	447.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_4650685_5	756272.Plabr_0279	4.153e-91	311.0	COG1262@1|root,COG1262@2|Bacteria,2IYGB@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_4650685_17	1173025.GEI7407_0339	1.904e-09	71.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
ZZS2_k127_4650685_12	1123242.JH636434_gene5244	4.036e-45	186.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4650685_2	857087.Metme_2805	1.573e-118	393.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RPUE@1236|Gammaproteobacteria,1XG0I@135618|Methylococcales	135618|Methylococcales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
ZZS2_k127_4650685_3	243233.MCA0314	2.145e-103	353.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1XG7I@135618|Methylococcales	135618|Methylococcales	O	HflC and HflK could regulate a protease	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
ZZS2_k127_467900_2	1382306.JNIM01000001_gene523	1.782e-54	218.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_467900_1	933262.AXAM01000068_gene2766	4.804e-141	456.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,2MN0X@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
ZZS2_k127_467900_5	1107311.Q767_00360	0.0006228	53.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NIU0@976|Bacteroidetes,1HXV1@117743|Flavobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_467900_4	984262.SGRA_1219	5.621e-06	59.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,4NJWK@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
ZZS2_k127_467900_3	411464.DESPIG_02010	5.51e-18	89.0	COG0355@1|root,COG0355@2|Bacteria,1N7PV@1224|Proteobacteria,42SYP@68525|delta/epsilon subdivisions,2X6HP@28221|Deltaproteobacteria,2MH36@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
ZZS2_k127_467900_0	1120919.AUBI01000010_gene85	2.578e-165	527.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,2JQ4B@204441|Rhodospirillales	204441|Rhodospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS2_k127_4745118_14	1121438.JNJA01000005_gene1187	5.697e-07	62.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2M98X@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_4745118_13	1396141.BATP01000005_gene6062	2.04e-21	99.0	COG1762@1|root,COG1762@2|Bacteria,46VMP@74201|Verrucomicrobia,2IUWS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
ZZS2_k127_4745118_7	314345.SPV1_05697	6.005e-63	228.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria	1224|Proteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
ZZS2_k127_4745118_8	314230.DSM3645_08617	3.458e-56	211.0	COG0009@1|root,COG0394@1|root,COG0009@2|Bacteria,COG0394@2|Bacteria,2IX5F@203682|Planctomycetes	203682|Planctomycetes	T	Belongs to the SUA5 family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,Sua5_yciO_yrdC
ZZS2_k127_4745118_9	575540.Isop_3481	1.718e-50	189.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	atoS	-	2.7.13.3	ko:K02482,ko:K07709,ko:K07710	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_8,PAS_9
ZZS2_k127_4745118_2	756272.Plabr_1901	4.993e-122	416.0	COG2204@1|root,COG2204@2|Bacteria,2IWYY@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_4745118_3	530564.Psta_4222	1.069e-112	372.0	COG0825@1|root,COG0825@2|Bacteria,2IX7N@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
ZZS2_k127_4745118_12	760568.Desku_0493	9.498e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4745118_15	396588.Tgr7_1087	2.988e-06	59.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_4745118_4	886293.Sinac_3776	9.484e-84	290.0	COG0820@1|root,COG0820@2|Bacteria,2IXW1@203682|Planctomycetes	203682|Planctomycetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
ZZS2_k127_4745118_1	1123405.AUMM01000005_gene882	2.554e-146	475.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,26N8N@186821|Sporolactobacillaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
ZZS2_k127_4745118_5	247490.KSU1_D0480	3.045e-83	286.0	COG0740@1|root,COG0740@2|Bacteria,2IXQN@203682|Planctomycetes	203682|Planctomycetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ZZS2_k127_4745118_10	717774.Marme_2578	1.089e-36	155.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1XHKR@135619|Oceanospirillales	135619|Oceanospirillales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
ZZS2_k127_4745118_0	760011.Spico_1334	5.406e-180	581.0	COG0445@1|root,COG0445@2|Bacteria,2J5A1@203691|Spirochaetes	203691|Spirochaetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
ZZS2_k127_4745118_11	1121890.AUDO01000008_gene2677	7.062e-30	126.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia,2NU9Y@237|Flavobacterium	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
ZZS2_k127_4745118_6	575540.Isop_1658	1.413e-71	256.0	COG0202@1|root,COG0457@1|root,COG0202@2|Bacteria,COG0457@2|Bacteria,2IXMK@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase alpha	-	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,TPR_1,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
ZZS2_k127_4745985_5	756272.Plabr_0828	2.445e-07	60.0	COG1595@1|root,COG1595@2|Bacteria,2IZPG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4745985_0	330214.NIDE1937	0.0	1540.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
ZZS2_k127_4745985_3	1492738.FEM21_11900	4.367e-88	299.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,1HYCT@117743|Flavobacteriia,2NV4B@237|Flavobacterium	976|Bacteroidetes	S	amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
ZZS2_k127_4745985_4	383372.Rcas_3789	1.39e-25	115.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_4745985_1	1122622.ATWJ01000008_gene2997	5.938e-148	502.0	COG0151@1|root,COG0151@2|Bacteria,2I7DG@201174|Actinobacteria,4FK12@85021|Intrasporangiaceae	201174|Actinobacteria	F	Carbamoyl-phosphate synthase L chain, ATP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
ZZS2_k127_4745985_2	880073.Calab_3584	8.322e-145	478.0	COG0297@1|root,COG0297@2|Bacteria,2NQKG@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
ZZS2_k127_4782866_5	1519464.HY22_13600	2.163e-33	130.0	COG1899@1|root,COG1899@2|Bacteria,1FDI8@1090|Chlorobi	1090|Chlorobi	H	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
ZZS2_k127_4782866_3	585425.KR52_10775	4.379e-56	208.0	COG0697@1|root,COG0697@2|Bacteria,1GHP7@1117|Cyanobacteria,1GYUN@1129|Synechococcus	1117|Cyanobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_4782866_0	1403819.BATR01000195_gene6595	3.458e-155	509.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
ZZS2_k127_4782866_4	215803.DB30_4861	1.095e-33	132.0	2AGBH@1|root,316H2@2|Bacteria,1PXKD@1224|Proteobacteria,434N3@68525|delta/epsilon subdivisions,2X8Y5@28221|Deltaproteobacteria,2Z0ZZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4782866_6	1385520.N802_08260	5.511e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,2GM5V@201174|Actinobacteria,4FGYN@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_4782866_2	1123242.JH636435_gene2023	2.575e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_4782866_1	452637.Oter_1389	9.43e-123	402.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_4836129_1	215803.DB30_1125	5.382e-54	205.0	COG1409@1|root,COG1409@2|Bacteria,1N2UT@1224|Proteobacteria,4376F@68525|delta/epsilon subdivisions,2X3M9@28221|Deltaproteobacteria,2YWHB@29|Myxococcales	28221|Deltaproteobacteria	S	Iron/zinc purple acid phosphatase-like protein C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Metallophos,Metallophos_C
ZZS2_k127_4836129_0	1121015.N789_01890	2.182e-187	597.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1S9NJ@1236|Gammaproteobacteria,1X5C8@135614|Xanthomonadales	135614|Xanthomonadales	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.12.1,1.14.15.7	ko:K00499,ko:K16319	ko00260,ko00627,ko01120,map00260,map00627,map01120	M00637	R00823,R00825,R07409	RC00087,RC00192	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS2_k127_4858209_2	756272.Plabr_0707	2.8e-09	63.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8
ZZS2_k127_4858209_1	450851.PHZ_c1673	2.153e-87	298.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4858209_5	1382359.JIAL01000001_gene794	0.0002886	50.0	COG1595@1|root,COG1595@2|Bacteria,3Y50V@57723|Acidobacteria,2JJJN@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_4858209_0	1149133.ppKF707_2955	9.285e-124	406.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,1S7AD@1236|Gammaproteobacteria,1YIQQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS2_k127_4858209_3	746697.Aeqsu_1982	5.306e-08	66.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,P_proprotein
ZZS2_k127_4858209_4	631362.Thi970DRAFT_03743	6.809e-07	61.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T23Q@1236|Gammaproteobacteria,1WXM7@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_4887385_8	1396141.BATP01000034_gene4202	2.326e-07	55.0	COG1409@1|root,COG2931@1|root,COG3210@1|root,COG3979@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3979@2|Bacteria,46XF9@74201|Verrucomicrobia,2IVRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	QU	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_4887385_1	1379698.RBG1_1C00001G1745	9.947e-77	264.0	COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria	2|Bacteria	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
ZZS2_k127_4887385_10	644281.MFS40622_0222	2.06e-05	56.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota,23R2D@183939|Methanococci	183939|Methanococci	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
ZZS2_k127_4887385_11	1155714.KB891994_gene4622	0.0002238	55.0	COG1520@1|root,COG4916@1|root,COG1520@2|Bacteria,COG4916@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
ZZS2_k127_4887385_5	379066.GAU_1412	2.052e-20	108.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
ZZS2_k127_4887385_0	871968.DESME_12225	3.643e-93	317.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,261AX@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
ZZS2_k127_4887385_2	595460.RRSWK_02292	1.019e-32	140.0	COG0509@1|root,COG0509@2|Bacteria,2J07Y@203682|Planctomycetes	203682|Planctomycetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
ZZS2_k127_4887385_4	497964.CfE428DRAFT_1799	3.428e-26	119.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS2_k127_4887385_3	765914.ThisiDRAFT_0506	3.635e-32	138.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WVYJ@135613|Chromatiales	135613|Chromatiales	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
ZZS2_k127_4887385_9	1265502.KB905929_gene2286	2.754e-06	57.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2VS76@28216|Betaproteobacteria,4AEGH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,CMD
ZZS2_k127_4887385_7	886293.Sinac_6754	3.483e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,2J02A@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_4887385_6	386456.JQKN01000009_gene1129	1.768e-11	76.0	COG3291@1|root,arCOG02555@1|root,arCOG07611@1|root,arCOG02546@2157|Archaea,arCOG02555@2157|Archaea,arCOG07611@2157|Archaea	2157|Archaea	E	Conserved repeat domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_5,CARDB,CHB_HEX_C_1,CarboxypepD_reg,Cellulase,DUF11,PKD,PQQ_3,SBBP,VWA
ZZS2_k127_4926951_0	1379698.RBG1_1C00001G1459	3.072e-124	407.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS2_k127_4926951_1	235909.GK3395	3.015e-103	344.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1WFG8@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
ZZS2_k127_4926951_2	7897.ENSLACP00000020544	3.836e-79	289.0	COG1960@1|root,KOG0139@2759|Eukaryota,38H6J@33154|Opisthokonta,3BC6X@33208|Metazoa,3CVK7@33213|Bilateria,48529@7711|Chordata,48V4V@7742|Vertebrata	33208|Metazoa	I	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	ACADS	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006139,GO:0006351,GO:0006352,GO:0006366,GO:0006367,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0010467,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016070,GO:0016491,GO:0016592,GO:0016627,GO:0017076,GO:0018130,GO:0019395,GO:0019438,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032787,GO:0032991,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0046483,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901567,GO:1901575,GO:1901576,GO:1901681	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_4926951_4	1121087.AUCK01000011_gene2033	1.114e-44	186.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus	91061|Bacilli	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
ZZS2_k127_4926951_5	1380390.JIAT01000009_gene385	9.827e-32	137.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPUT@84995|Rubrobacteria	84995|Rubrobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_4926951_10	1123508.JH636439_gene1468	1.762e-10	75.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,2IZTN@203682|Planctomycetes	203682|Planctomycetes	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
ZZS2_k127_4926951_11	404589.Anae109_1402	5.46e-05	55.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS2_k127_4926951_6	237368.SCABRO_02942	3.173e-27	126.0	COG0795@1|root,COG0795@2|Bacteria,2IZHF@203682|Planctomycetes	203682|Planctomycetes	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS2_k127_4926951_12	1142394.PSMK_06260	0.0002758	55.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
ZZS2_k127_4926951_7	1485543.JMME01000003_gene1906	4.314e-23	105.0	COG1487@1|root,COG1487@2|Bacteria,1VCFS@1239|Firmicutes,4H7VU@909932|Negativicutes	909932|Negativicutes	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
ZZS2_k127_4926951_9	1121403.AUCV01000040_gene4277	2.72e-11	68.0	COG4456@1|root,COG4456@2|Bacteria,1N7FM@1224|Proteobacteria,42VSD@68525|delta/epsilon subdivisions,2WSAY@28221|Deltaproteobacteria,2MMA1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
ZZS2_k127_4926951_8	1144275.COCOR_01519	6.516e-16	93.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_4926951_3	35754.JNYJ01000012_gene925	7.497e-49	178.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4DDSB@85008|Micromonosporales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS2_k127_5041469_2	502025.Hoch_5785	7.078e-43	163.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
ZZS2_k127_5041469_1	1123242.JH636434_gene4980	8.629e-94	312.0	COG0262@1|root,COG0262@2|Bacteria,2IYX1@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS2_k127_5041469_0	314230.DSM3645_28167	1.83e-129	428.0	COG3039@1|root,COG3039@2|Bacteria,2J1M4@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
ZZS2_k127_5041469_3	543728.Vapar_5423	3.39e-37	143.0	28PTH@1|root,2ZCER@2|Bacteria,1NYBV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5080913_4	1120950.KB892779_gene911	6.387e-07	59.0	COG0305@1|root,COG0305@2|Bacteria,2I62I@201174|Actinobacteria,4DVRH@85009|Propionibacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987,DnaB
ZZS2_k127_5080913_3	1254432.SCE1572_31700	3.471e-09	62.0	COG2963@1|root,COG2963@2|Bacteria,1NGD6@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
ZZS2_k127_5080913_2	240016.ABIZ01000001_gene4624	8.209e-30	124.0	COG3436@1|root,COG3436@2|Bacteria	2|Bacteria	L	PFAM IS66 Orf2 family protein	tnpB	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
ZZS2_k127_5080913_0	314230.DSM3645_28142	7.379e-102	350.0	COG3316@1|root,COG3316@2|Bacteria,2J4XX@203682|Planctomycetes	203682|Planctomycetes	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
ZZS2_k127_5080913_1	701347.Entcl_0654	2.759e-65	231.0	COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria,1RMUN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
ZZS2_k127_5086243_1	391625.PPSIR1_03213	3.353e-109	376.0	COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_5086243_0	1089550.ATTH01000001_gene237	3.744e-158	520.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS2_k127_5086243_2	1210884.HG799462_gene8615	2.215e-36	158.0	COG0515@1|root,COG0515@2|Bacteria,2IYAA@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_5116584_10	269797.Mbar_A1800	2.032e-23	117.0	COG1520@1|root,COG3291@1|root,arCOG02550@1|root,arCOG03991@1|root,arCOG02482@2157|Archaea,arCOG02510@2157|Archaea,arCOG02550@2157|Archaea,arCOG03991@2157|Archaea,2XUI1@28890|Euryarchaeota,2NBKW@224756|Methanomicrobia	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM_6,DUF3344,NosD,PKD,PQQ_2,PQQ_3,Pkinase
ZZS2_k127_5116584_9	1123070.KB899253_gene1114	1.704e-23	109.0	2FECS@1|root,346CJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5116584_14	1123366.TH3_12095	5.67e-08	66.0	COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,2UHNU@28211|Alphaproteobacteria,2JUAV@204441|Rhodospirillales	204441|Rhodospirillales	I	3-hydroxylacyl-(Acyl carrier protein) dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	FabA
ZZS2_k127_5116584_13	1117647.M5M_07010	3.001e-09	70.0	2DNSX@1|root,32YZ0@2|Bacteria,1NDSG@1224|Proteobacteria,1T3PH@1236|Gammaproteobacteria,1JC3B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
ZZS2_k127_5116584_3	391625.PPSIR1_04533	3.455e-92	316.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,42PU1@68525|delta/epsilon subdivisions,2X5K4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS2_k127_5116584_6	391625.PPSIR1_04548	7.414e-78	268.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_5116584_11	760568.Desku_0353	1.21e-21	98.0	COG2442@1|root,COG2442@2|Bacteria,1VB42@1239|Firmicutes,25PS9@186801|Clostridia,2638V@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
ZZS2_k127_5116584_12	429009.Adeg_1354	1.877e-20	94.0	COG4634@1|root,COG4634@2|Bacteria,1VXGB@1239|Firmicutes,251NY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
ZZS2_k127_5116584_1	1047013.AQSP01000144_gene927	2.037e-177	584.0	COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
ZZS2_k127_5116584_0	1432055.GLUCORHAEAF1_01150	6.915e-181	580.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales	204441|Rhodospirillales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
ZZS2_k127_5116584_2	575540.Isop_3177	3.935e-117	413.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
ZZS2_k127_5116584_4	1267533.KB906740_gene260	1.042e-89	301.0	COG0666@1|root,COG0666@2|Bacteria,3Y6XF@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4
ZZS2_k127_5116584_8	926550.CLDAP_01930	2.048e-34	151.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
ZZS2_k127_5116584_7	1192034.CAP_8052	1.071e-47	190.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YY53@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5116584_5	506534.Rhein_0859	1.944e-89	309.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1WVVW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
ZZS2_k127_5134986_4	886293.Sinac_4346	5.023e-53	196.0	COG4102@1|root,COG4102@2|Bacteria,2IYA1@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5134986_0	398512.JQKC01000061_gene3002	1.641e-106	375.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,2486M@186801|Clostridia,3WM05@541000|Ruminococcaceae	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2
ZZS2_k127_5134986_1	935845.JADQ01000029_gene1230	6.349e-104	372.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
ZZS2_k127_5134986_5	1121022.ABENE_20090	4.198e-47	185.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2U5VQ@28211|Alphaproteobacteria,2KH46@204458|Caulobacterales	204458|Caulobacterales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
ZZS2_k127_5134986_7	483219.LILAB_30070	8.19e-08	67.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_5134986_6	1283287.KB822575_gene347	6.223e-08	68.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4DR4E@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	sigL	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_5134986_2	1122164.JHWF01000027_gene921	6.302e-99	352.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,1T553@1236|Gammaproteobacteria,1JEEF@118969|Legionellales	118969|Legionellales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
ZZS2_k127_5134986_3	215803.DB30_0571	1.791e-59	212.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,42TP3@68525|delta/epsilon subdivisions,2WR14@28221|Deltaproteobacteria,2Z032@29|Myxococcales	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
ZZS2_k127_5147297_5	1254432.SCE1572_22375	1.129e-47	195.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5147297_4	670307.HYPDE_33213	3.276e-51	201.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
ZZS2_k127_5147297_0	1172188.KB911820_gene2095	5.838e-112	379.0	COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4FE3S@85021|Intrasporangiaceae	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
ZZS2_k127_5147297_3	1380393.JHVP01000005_gene3586	2.326e-56	213.0	COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
ZZS2_k127_5147297_7	1282876.BAOK01000001_gene1486	1.509e-14	88.0	COG4552@1|root,COG4552@2|Bacteria,1NJ0B@1224|Proteobacteria	1224|Proteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
ZZS2_k127_5147297_2	1254432.SCE1572_34895	1.851e-70	247.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2WJW1@28221|Deltaproteobacteria,2YUUB@29|Myxococcales	28221|Deltaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
ZZS2_k127_5147297_6	448385.sce9192	1.109e-36	159.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,42PRH@68525|delta/epsilon subdivisions,2X6F3@28221|Deltaproteobacteria,2Z32C@29|Myxococcales	28221|Deltaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
ZZS2_k127_5147297_1	1408473.JHXO01000002_gene3961	1.509e-111	371.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,2FUVV@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_5160531_15	357808.RoseRS_3392	3.992e-05	56.0	COG1413@1|root,COG1413@2|Bacteria,2G6UU@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_5160531_12	1158760.AQXP01000033_gene985	4.007e-12	69.0	2EPQJ@1|root,33HB4@2|Bacteria,1NIAD@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3634
ZZS2_k127_5160531_0	1210884.HG799473_gene14952	1.064e-150	503.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2IY3H@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
ZZS2_k127_5160531_8	118173.KB235914_gene2153	5.616e-37	147.0	29699@1|root,2ZTJA@2|Bacteria	2|Bacteria	S	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
ZZS2_k127_5160531_7	240292.Ava_1520	1.93e-45	186.0	COG1680@1|root,COG1680@2|Bacteria,1G5Z2@1117|Cyanobacteria,1HIVF@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_5160531_13	1380390.JIAT01000010_gene3372	8.046e-09	69.0	COG1309@1|root,COG1309@2|Bacteria,2GN9E@201174|Actinobacteria,4CSZT@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_5160531_1	886293.Sinac_2122	2.86e-148	484.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
ZZS2_k127_5160531_6	357808.RoseRS_0991	2.965e-50	207.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
ZZS2_k127_5160531_14	1304865.JAGF01000001_gene1253	4.934e-07	64.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4F226@85016|Cellulomonadaceae	201174|Actinobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ZZS2_k127_5160531_9	1191523.MROS_1179	2.623e-36	145.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nifU	-	-	-	-	-	-	-	-	-	-	-	NifU
ZZS2_k127_5160531_16	1121104.AQXH01000008_gene2376	7.54e-05	52.0	2ESUZ@1|root,33KDD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5160531_17	324602.Caur_2828	0.0006992	53.0	COG0457@1|root,COG0457@2|Bacteria,2GBDY@200795|Chloroflexi,375DC@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
ZZS2_k127_5160531_5	880072.Desac_0508	3.553e-52	202.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2MQE4@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
ZZS2_k127_5160531_10	215803.DB30_8118	5.93e-33	140.0	COG1940@1|root,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,42SQD@68525|delta/epsilon subdivisions,2WPSD@28221|Deltaproteobacteria,2YZ89@29|Myxococcales	28221|Deltaproteobacteria	G	Glucokinase	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS2_k127_5160531_2	1121468.AUBR01000030_gene1226	7.872e-140	458.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS2_k127_5160531_11	247490.KSU1_B0311	1.367e-20	104.0	COG0236@1|root,COG0236@2|Bacteria,2J0V5@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS2_k127_5160531_4	552398.HMPREF0866_00060	1.738e-78	269.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_5160531_3	370438.PTH_1745	4.346e-80	275.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS2_k127_516855_16	477184.KYC_18590	2.069e-21	105.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,3T7BM@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_516855_18	684949.ATTJ01000001_gene503	1.107e-06	63.0	COG2911@1|root,COG2911@2|Bacteria,1WJAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
ZZS2_k127_516855_8	589865.DaAHT2_2138	1.852e-68	262.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	68525|delta/epsilon subdivisions	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
ZZS2_k127_516855_9	1396141.BATP01000001_gene5390	9.877e-67	247.0	COG2911@1|root,COG2911@2|Bacteria,46UAP@74201|Verrucomicrobia,2IVR8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_516855_0	1122132.AQYH01000007_gene2183	0.0	1138.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria,4B9XB@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	-	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
ZZS2_k127_516855_1	1122132.AQYH01000007_gene2182	6.968e-257	802.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2U1RU@28211|Alphaproteobacteria,4BB0R@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
ZZS2_k127_516855_2	172088.AUGA01000007_gene8273	8.57e-255	796.0	COG0436@1|root,COG0436@2|Bacteria,1QE0D@1224|Proteobacteria,2U24M@28211|Alphaproteobacteria,3JU4F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	-	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
ZZS2_k127_516855_3	1449065.JMLL01000012_gene3738	5.616e-240	754.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2U1RU@28211|Alphaproteobacteria,43MQW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted Permease Membrane Region	-	-	-	-	-	-	-	-	-	-	-	-	Asp-Al_Ex,TrkA_C
ZZS2_k127_516855_10	452637.Oter_1144	1.39e-62	226.0	COG2860@1|root,COG2860@2|Bacteria,46T5E@74201|Verrucomicrobia,3K7YJ@414999|Opitutae	414999|Opitutae	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
ZZS2_k127_516855_4	357808.RoseRS_4055	8.782e-127	417.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,3755X@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
ZZS2_k127_516855_7	1304880.JAGB01000002_gene1669	1.321e-68	258.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
ZZS2_k127_516855_6	498761.HM1_1724	2.461e-96	326.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
ZZS2_k127_516855_11	448385.sce8681	4.799e-58	220.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ZZS2_k127_516855_12	1463825.JNXC01000029_gene475	1.285e-49	203.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4DY4W@85010|Pseudonocardiales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS2_k127_516855_17	330214.NIDE2245	2.285e-20	106.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_5,Fer4_9
ZZS2_k127_516855_5	237368.SCABRO_03967	1.815e-106	369.0	COG1132@1|root,COG1132@2|Bacteria,2IXKY@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_516855_13	861299.J421_3264	3.351e-36	147.0	COG0245@1|root,COG0245@2|Bacteria,1ZTM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
ZZS2_k127_516855_15	279010.BL03265	3.725e-27	113.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
ZZS2_k127_5192738_26	32057.KB217478_gene912	5.007e-05	50.0	COG3016@1|root,COG3016@2|Bacteria,1G1JQ@1117|Cyanobacteria,1HRKQ@1161|Nostocales	1117|Cyanobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
ZZS2_k127_5192738_18	1390370.O203_07990	3.377e-33	138.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	2.7.7.65	ko:K02488,ko:K21009	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
ZZS2_k127_5192738_0	469383.Cwoe_3437	3.567e-130	422.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
ZZS2_k127_5192738_17	216594.MMAR_5183	3.646e-35	139.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,239AY@1762|Mycobacteriaceae	201174|Actinobacteria	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
ZZS2_k127_5192738_15	469383.Cwoe_3439	1.962e-39	155.0	COG2172@1|root,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
ZZS2_k127_5192738_16	1380391.JIAS01000015_gene78	1.209e-35	143.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria,2U953@28211|Alphaproteobacteria,2JUWV@204441|Rhodospirillales	204441|Rhodospirillales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
ZZS2_k127_5192738_21	258594.RPA1490	2.038e-31	136.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TWHG@28211|Alphaproteobacteria,3JZYI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Phytochrome region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HWE_HK,HisKA_3,PAS_2,PHY,Response_reg
ZZS2_k127_5192738_12	497964.CfE428DRAFT_4671	6.82e-46	185.0	COG2197@1|root,COG2197@2|Bacteria,46VG0@74201|Verrucomicrobia	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
ZZS2_k127_5192738_7	713586.KB900536_gene2146	6.059e-75	264.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
ZZS2_k127_5192738_8	768710.DesyoDRAFT_1409	4.193e-69	246.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,261DY@186807|Peptococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5192738_23	65093.PCC7418_2945	6.887e-21	102.0	COG2258@1|root,COG2258@2|Bacteria,1G6F8@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5192738_5	945713.IALB_2784	2.567e-85	312.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
ZZS2_k127_5192738_10	42256.RradSPS_2430	3.731e-51	205.0	COG3361@1|root,COG3361@2|Bacteria,2I6N0@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
ZZS2_k127_5192738_13	1254432.SCE1572_07220	3.373e-44	170.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,43BYG@68525|delta/epsilon subdivisions,2X3A9@28221|Deltaproteobacteria,2YV3A@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS2_k127_5192738_22	880072.Desac_1433	1.839e-23	117.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MQKC@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS2_k127_5192738_1	886293.Sinac_6493	9.727e-117	400.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS2_k127_5192738_14	349124.Hhal_0421	2.903e-41	171.0	COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,1T3FR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
ZZS2_k127_5192738_20	269799.Gmet_0766	8.478e-32	137.0	COG0438@1|root,COG0438@2|Bacteria,1N2C6@1224|Proteobacteria,42UQ0@68525|delta/epsilon subdivisions,2WQU7@28221|Deltaproteobacteria,43UCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5192738_19	396588.Tgr7_0663	1.169e-32	147.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WVYJ@135613|Chromatiales	135613|Chromatiales	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
ZZS2_k127_5192738_4	983917.RGE_04160	1.344e-86	301.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,1KMBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
ZZS2_k127_5192738_6	1122603.ATVI01000006_gene524	1.545e-82	305.0	COG2133@1|root,COG3386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,1R2KP@1224|Proteobacteria,1T5SI@1236|Gammaproteobacteria,1XB12@135614|Xanthomonadales	2|Bacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
ZZS2_k127_5192738_9	743722.Sph21_0787	9.448e-55	201.0	COG1131@1|root,COG1131@2|Bacteria,4NJ0D@976|Bacteroidetes,1IQ6J@117747|Sphingobacteriia	976|Bacteroidetes	V	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5192738_24	156889.Mmc1_2863	6.672e-07	60.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,2UGII@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4351)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_5192738_11	448385.sce8068	9.006e-47	182.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria,2YV8F@29|Myxococcales	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_5192738_25	745014.OMB55_00001040	2.803e-05	55.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	2.7.13.3	ko:K03407,ko:K03832	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	2.C.1.1	-	-	CarbopepD_reg_2,GUN4,Gram_pos_anchor,HAMP,NIT,TonB_2,TonB_C,Trypsin_2
ZZS2_k127_5192738_2	1123354.AUDR01000018_gene1126	7.029e-104	351.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KRXA@119069|Hydrogenophilales	119069|Hydrogenophilales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
ZZS2_k127_5192738_3	1303518.CCALI_01587	6.442e-102	342.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
ZZS2_k127_5200493_22	247490.KSU1_C1631	5.253e-08	65.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
ZZS2_k127_5200493_7	1517416.IDAT_09255	1.59e-81	279.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,2QF8T@267893|Idiomarinaceae	1236|Gammaproteobacteria	P	Integral membrane protein TerC family	ygdQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TerC
ZZS2_k127_5200493_9	1242864.D187_007363	2.014e-72	276.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5200493_14	290397.Adeh_0162	9.699e-48	190.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2WM6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
ZZS2_k127_5200493_13	314230.DSM3645_29606	8.386e-48	188.0	COG0105@1|root,COG0105@2|Bacteria,2IZQ6@203682|Planctomycetes	203682|Planctomycetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
ZZS2_k127_5200493_2	401526.TcarDRAFT_1906	5.331e-171	551.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H23Y@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
ZZS2_k127_5200493_1	1121382.JQKG01000009_gene768	8.079e-176	568.0	COG4108@1|root,COG4108@2|Bacteria,1WNE7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
ZZS2_k127_5200493_4	448385.sce0867	7.745e-116	381.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,43B30@68525|delta/epsilon subdivisions,2X6GS@28221|Deltaproteobacteria,2Z3B0@29|Myxococcales	28221|Deltaproteobacteria	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
ZZS2_k127_5200493_19	1048983.EL17_20365	6.152e-12	76.0	28JEH@1|root,2Z98N@2|Bacteria,4NJHC@976|Bacteroidetes,47MQN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5200493_12	1288298.rosmuc_03877	1.169e-48	197.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,46PUR@74030|Roseovarius	28211|Alphaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
ZZS2_k127_5200493_15	696281.Desru_2219	7.986e-41	159.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,261GZ@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
ZZS2_k127_5200493_11	1333998.M2A_3052	1.865e-66	236.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,4BQ5K@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941,ko:K18824	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Pterin_bind
ZZS2_k127_5200493_10	243090.RB12526	2.765e-68	246.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS2_k127_5200493_8	797304.Natgr_0037	7.318e-76	267.0	arCOG06187@1|root,arCOG06187@2157|Archaea,2XTSP@28890|Euryarchaeota,23S9E@183963|Halobacteria	183963|Halobacteria	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5200493_6	1278073.MYSTI_03237	1.382e-88	327.0	COG0860@1|root,COG0860@2|Bacteria,1NTG0@1224|Proteobacteria	1224|Proteobacteria	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
ZZS2_k127_5200493_21	312309.VF_0554	1.2e-08	60.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,1XUE1@135623|Vibrionales	135623|Vibrionales	E	T-protein	tyrA	-	1.3.1.12,5.4.99.5	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
ZZS2_k127_5200493_0	1242864.D187_002339	0.0	1021.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2WMKS@28221|Deltaproteobacteria,2YWJ3@29|Myxococcales	28221|Deltaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
ZZS2_k127_5200493_16	448385.sce4076	3.361e-40	164.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria,2YV8F@29|Myxococcales	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_5200493_3	247490.KSU1_C0206	2.167e-141	460.0	COG0151@1|root,COG0151@2|Bacteria,2IX58@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
ZZS2_k127_5200493_17	404589.Anae109_2251	7.023e-30	130.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,2YVE5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ZZS2_k127_5200493_5	1125863.JAFN01000001_gene1446	1.337e-108	372.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_5200493_18	1094980.Mpsy_1538	6.705e-26	126.0	COG2304@1|root,COG4934@1|root,arCOG02902@2157|Archaea,arCOG03665@2157|Archaea	2157|Archaea	O	tripeptidyl-peptidase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,Peptidase_S8,Pro-kuma_activ,VWA,VWA_2
ZZS2_k127_5200493_20	1121373.KB903622_gene2818	3.574e-11	78.0	COG5434@1|root,COG5434@2|Bacteria,4NQP8@976|Bacteroidetes,47QU1@768503|Cytophagia	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS2_k127_5218801_2	1459636.NTE_00907	5.442e-08	63.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K03294,ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6,2.A.3.2	-	-	Usp
ZZS2_k127_5218801_0	1047013.AQSP01000140_gene2549	2.952e-130	452.0	COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria	2|Bacteria	O	peptidase S16	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
ZZS2_k127_5218801_1	497964.CfE428DRAFT_3779	1.9e-107	372.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MIT_C
ZZS2_k127_5221751_0	237368.SCABRO_02658	7.228e-223	721.0	COG0013@1|root,COG0013@2|Bacteria,2IX30@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ZZS2_k127_5221751_3	272632.MSC_0593	4.342e-12	71.0	COG0333@1|root,COG0333@2|Bacteria,3WTYB@544448|Tenericutes	544448|Tenericutes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
ZZS2_k127_5221751_1	1121468.AUBR01000030_gene1220	8.016e-69	246.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,42F74@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
ZZS2_k127_5221751_2	1268072.PSAB_11895	4.91e-58	207.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS2_k127_5233034_22	314271.RB2654_21068	7.632e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5233034_6	886293.Sinac_0410	2.999e-114	413.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_5233034_12	1205680.CAKO01000006_gene3363	1.193e-47	180.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_5233034_17	1267533.KB906733_gene2926	7.469e-19	101.0	COG3801@1|root,COG3801@2|Bacteria,3Y5K2@57723|Acidobacteria,2JNJG@204432|Acidobacteriia	204432|Acidobacteriia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
ZZS2_k127_5233034_4	243090.RB7228	1.722e-138	463.0	COG3119@1|root,COG3119@2|Bacteria,2IX1H@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_5233034_0	886293.Sinac_2223	4.306e-205	694.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_5233034_7	1128421.JAGA01000001_gene2450	4.672e-71	259.0	COG1613@1|root,COG1613@2|Bacteria,2NQGY@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
ZZS2_k127_5233034_8	485918.Cpin_4697	3.887e-67	238.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1IQJP@117747|Sphingobacteriia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
ZZS2_k127_5233034_15	491205.JARQ01000002_gene132	2.382e-24	117.0	2EGQS@1|root,33AGX@2|Bacteria,4P6HT@976|Bacteroidetes,1IGMM@117743|Flavobacteriia,3ZRAD@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5233034_9	1122939.ATUD01000001_gene577	4.665e-56	224.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5233034_2	502025.Hoch_3167	1.234e-189	657.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
ZZS2_k127_5233034_16	530564.Psta_4046	3.382e-22	111.0	COG1595@1|root,COG1595@2|Bacteria,2IZJE@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5233034_5	1267535.KB906767_gene1180	6.963e-120	398.0	COG0388@1|root,COG0388@2|Bacteria,3Y7FJ@57723|Acidobacteria	57723|Acidobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
ZZS2_k127_5233034_13	452637.Oter_4047	6.485e-46	169.0	COG1765@1|root,COG1765@2|Bacteria,46T1Y@74201|Verrucomicrobia,3K87D@414999|Opitutae	414999|Opitutae	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS2_k127_5233034_23	72019.SARC_01947T0	5.308e-05	54.0	COG0484@1|root,KOG0550@2759|Eukaryota	2759|Eukaryota	O	chaperone cofactor-dependent protein refolding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
ZZS2_k127_5233034_18	215803.DB30_2422	2.562e-16	94.0	COG0750@1|root,COG4932@1|root,COG0750@2|Bacteria,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_5233034_11	180281.CPCC7001_462	6.202e-51	196.0	COG0697@1|root,COG0697@2|Bacteria,1GB7Y@1117|Cyanobacteria,22S63@167375|Cyanobium	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_5233034_3	639030.JHVA01000001_gene708	2.561e-143	465.0	COG1899@1|root,COG1899@2|Bacteria,3Y5EW@57723|Acidobacteria,2JJNA@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
ZZS2_k127_5233034_20	1041159.AZUW01000016_gene1566	3.457e-14	85.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2U2JV@28211|Alphaproteobacteria,4BMNA@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	ytfQ	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS2_k127_5233034_14	1282876.BAOK01000001_gene2277	3.699e-32	139.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5233034_10	243233.MCA2966	1.149e-55	205.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales	135618|Methylococcales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
ZZS2_k127_5233034_1	497964.CfE428DRAFT_4539	6.337e-195	630.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
ZZS2_k127_5239691_4	1144342.PMI40_02385	4.412e-35	138.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,474F3@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
ZZS2_k127_5239691_5	1121380.JNIW01000015_gene2616	6.744e-12	79.0	COG2340@1|root,COG2340@2|Bacteria,1WKKZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CAP
ZZS2_k127_5239691_6	1173028.ANKO01000114_gene6121	2.629e-11	70.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7TA@1150|Oscillatoriales	1117|Cyanobacteria	M	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	WD40
ZZS2_k127_5239691_1	1123060.JONP01000007_gene5042	3.291e-96	327.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639,ko:K15045	ko00790,ko01100,ko04122,ko05164,map00790,map01100,map04122,map05164	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
ZZS2_k127_5239691_2	1408418.JNJH01000001_gene3036	2.737e-64	234.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2JQ88@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5239691_0	861299.J421_5777	3.301e-116	401.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639,ko:K15045	ko00790,ko01100,ko04122,ko05164,map00790,map01100,map04122,map05164	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
ZZS2_k127_5239691_7	240016.ABIZ01000001_gene4878	7.014e-07	62.0	COG3209@1|root,COG3266@1|root,COG4782@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG4782@2|Bacteria,46S8F@74201|Verrucomicrobia,2IV48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
ZZS2_k127_5239691_3	234267.Acid_4318	2.263e-46	176.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
ZZS2_k127_5273894_0	518766.Rmar_2370	6.575e-290	915.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1FITW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
ZZS2_k127_5273894_5	926550.CLDAP_20390	2.687e-23	104.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
ZZS2_k127_5273894_1	1118054.CAGW01000017_gene4496	1.444e-113	382.0	COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,26SEA@186822|Paenibacillaceae	91061|Bacilli	C	virulence factor	ypgR	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact
ZZS2_k127_5273894_7	391612.CY0110_05637	2.608e-08	66.0	COG0515@1|root,COG0515@2|Bacteria,1G08U@1117|Cyanobacteria,3KH6Q@43988|Cyanothece	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_5273894_6	91464.S7335_3598	2.326e-14	87.0	COG2931@1|root,COG2931@2|Bacteria,1G6NS@1117|Cyanobacteria,1H1HT@1129|Synechococcus	1117|Cyanobacteria	Q	secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Peptidase_S8
ZZS2_k127_5273894_4	266835.14023881	3.168e-27	126.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5MK@28211|Alphaproteobacteria,43K3B@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
ZZS2_k127_5273894_3	861299.J421_6003	5.586e-56	203.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
ZZS2_k127_5273894_2	909663.KI867150_gene140	3.699e-89	313.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2MQRZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Divalent cation transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
ZZS2_k127_5274751_0	344747.PM8797T_10669	3.639e-105	359.0	COG4974@1|root,COG4974@2|Bacteria,2IXH0@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
ZZS2_k127_5274751_2	240016.ABIZ01000001_gene4624	3.259e-23	101.0	COG3436@1|root,COG3436@2|Bacteria	2|Bacteria	L	PFAM IS66 Orf2 family protein	tnpB	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
ZZS2_k127_5274751_3	1121451.DESAM_21799	1.044e-10	73.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2M93X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS2_k127_5274751_1	1499967.BAYZ01000152_gene1402	5.123e-80	277.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
ZZS2_k127_5274751_5	469383.Cwoe_5871	2.23e-06	53.0	COG1595@1|root,COG2071@1|root,COG1595@2|Bacteria,COG2071@2|Bacteria	2|Bacteria	S	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	-	-	-	ko:K03088,ko:K07010	-	-	-	-	ko00000,ko01002,ko03021	-	-	-	Peptidase_C26
ZZS2_k127_5386745_12	640081.Dsui_2290	1.391e-05	55.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,2KW39@206389|Rhodocyclales	206389|Rhodocyclales	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
ZZS2_k127_5386745_9	452637.Oter_1153	8.199e-09	65.0	COG2995@1|root,COG2995@2|Bacteria,46YQG@74201|Verrucomicrobia,3KA02@414999|Opitutae	414999|Opitutae	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
ZZS2_k127_5386745_1	1192034.CAP_0766	3.882e-75	259.0	COG0640@1|root,COG0640@2|Bacteria,1RCIH@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS2_k127_5386745_2	886293.Sinac_3110	5.283e-72	261.0	COG3832@1|root,COG3832@2|Bacteria,2J27S@203682|Planctomycetes	203682|Planctomycetes	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5386745_6	1192034.CAP_8308	9.88e-55	213.0	COG3220@1|root,COG3220@2|Bacteria,1Q38G@1224|Proteobacteria,438ZE@68525|delta/epsilon subdivisions,2X44P@28221|Deltaproteobacteria,2YY8Z@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
ZZS2_k127_5386745_10	1254432.SCE1572_00825	1.085e-08	64.0	2BGYF@1|root,32AYH@2|Bacteria,1QAYP@1224|Proteobacteria,435CU@68525|delta/epsilon subdivisions,2WZQB@28221|Deltaproteobacteria,2Z2IB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5386745_3	886293.Sinac_3618	7.646e-60	233.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_5386745_7	443144.GM21_1424	3.777e-33	144.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5386745_5	448385.sce8846	1.91e-56	198.0	COG0640@1|root,COG0640@2|Bacteria,1RH4V@1224|Proteobacteria,43AH1@68525|delta/epsilon subdivisions,2X5X1@28221|Deltaproteobacteria,2Z038@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS2_k127_5386745_4	1500301.JQMF01000024_gene1983	3.018e-59	209.0	COG3832@1|root,COG3832@2|Bacteria,1RJKI@1224|Proteobacteria,2UAQG@28211|Alphaproteobacteria,4BCHX@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS2_k127_5386745_0	1396141.BATP01000027_gene1109	9.997e-87	303.0	COG4775@1|root,COG4775@2|Bacteria,46UZC@74201|Verrucomicrobia,2IV9A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
ZZS2_k127_5386745_11	404589.Anae109_0398	5.431e-07	62.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_5456037_11	316274.Haur_1733	3.188e-23	115.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS2_k127_5456037_6	1210884.HG799473_gene14941	5.832e-54	198.0	2CAZH@1|root,2Z7RU@2|Bacteria,2IZW6@203682|Planctomycetes	203682|Planctomycetes	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
ZZS2_k127_5456037_14	574087.Acear_0621	5.71e-07	61.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,3WBT4@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
ZZS2_k127_5456037_5	886293.Sinac_5576	1.218e-78	287.0	COG0761@1|root,COG0761@2|Bacteria,2IXK4@203682|Planctomycetes	203682|Planctomycetes	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,UbiA
ZZS2_k127_5456037_10	886293.Sinac_4846	1.055e-24	117.0	COG0526@1|root,COG0526@2|Bacteria,2J12A@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
ZZS2_k127_5456037_7	1122604.JONR01000006_gene2524	3.588e-51	194.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria,1X47H@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
ZZS2_k127_5456037_0	1278073.MYSTI_03662	6.206e-266	834.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria,2YUMS@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
ZZS2_k127_5456037_15	1121288.AULL01000013_gene1683	3.537e-06	58.0	COG3227@1|root,COG3227@2|Bacteria,4PM0G@976|Bacteroidetes,1IJI5@117743|Flavobacteriia,3ZSCE@59732|Chryseobacterium	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5456037_3	891968.Anamo_1556	4.249e-92	313.0	COG1052@1|root,COG1052@2|Bacteria,3TARR@508458|Synergistetes	508458|Synergistetes	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS2_k127_5456037_4	1267533.KB906737_gene1568	3.117e-79	292.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria,2JID2@204432|Acidobacteriia	204432|Acidobacteriia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
ZZS2_k127_5456037_2	234267.Acid_1100	8.802e-128	423.0	COG1696@1|root,COG1696@2|Bacteria,3Y4S9@57723|Acidobacteria	57723|Acidobacteria	M	PFAM membrane bound O-acyl transferase MBOAT	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
ZZS2_k127_5456037_13	497964.CfE428DRAFT_4687	3.184e-09	71.0	COG3209@1|root,COG5276@1|root,COG3209@2|Bacteria,COG5276@2|Bacteria,46Z8T@74201|Verrucomicrobia	74201|Verrucomicrobia	M	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5456037_9	880073.Calab_3019	8.355e-30	132.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
ZZS2_k127_5456037_1	886293.Sinac_4702	3.485e-190	607.0	COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
ZZS2_k127_5456037_8	886293.Sinac_4133	6.978e-44	165.0	COG5649@1|root,COG5649@2|Bacteria,2J2FF@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS2_k127_5456037_16	1155718.KB891878_gene5583	2.02e-05	58.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
ZZS2_k127_5465280_0	1254432.SCE1572_21885	2.769e-187	599.0	COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,439ZZ@68525|delta/epsilon subdivisions,2X4EZ@28221|Deltaproteobacteria,2YYW8@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.77,1.2.1.91,3.3.2.12	ko:K02618,ko:K15514	ko00360,ko00362,ko01120,map00360,map00362,map01120	-	R09554,R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh
ZZS2_k127_5465280_6	386456.JQKN01000001_gene2372	1.219e-11	78.0	arCOG03946@1|root,arCOG03946@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4015,PMBR
ZZS2_k127_5465280_2	314230.DSM3645_10162	1.004e-101	342.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS2_k127_5465280_5	314230.DSM3645_10252	6.026e-23	112.0	COG0392@1|root,COG0392@2|Bacteria,2IZNF@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS2_k127_5465280_3	1121468.AUBR01000032_gene1172	2.571e-33	139.0	COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,42GR7@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
ZZS2_k127_5465280_1	572477.Alvin_1965	4.935e-118	392.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS2_k127_5465280_4	765914.ThisiDRAFT_1770	5.955e-30	138.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales	135613|Chromatiales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ZZS2_k127_5465280_7	269797.Mbar_A0925	0.0007429	53.0	COG1413@1|root,arCOG02966@2157|Archaea	2157|Archaea	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_5469887_2	661478.OP10G_1529	3.459e-152	498.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS2_k127_5469887_7	869210.Marky_1874	1.31e-37	146.0	COG2318@1|root,COG2318@2|Bacteria,1WKK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS2_k127_5469887_0	575540.Isop_3735	4.109e-245	769.0	COG1866@1|root,COG1866@2|Bacteria,2IYC0@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
ZZS2_k127_5469887_8	502025.Hoch_0540	5.79e-35	137.0	COG0720@1|root,COG0720@2|Bacteria,1RI8E@1224|Proteobacteria,435ED@68525|delta/epsilon subdivisions,2WZS2@28221|Deltaproteobacteria,2Z2MH@29|Myxococcales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PTPS
ZZS2_k127_5469887_1	335543.Sfum_1234	1.525e-163	539.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MQ7E@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ZZS2_k127_5469887_14	521674.Plim_2697	1.883e-13	74.0	COG1918@1|root,COG1918@2|Bacteria,2J0K6@203682|Planctomycetes	203682|Planctomycetes	P	COG1918 Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
ZZS2_k127_5469887_3	1210884.HG799468_gene13632	1.121e-121	417.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
ZZS2_k127_5469887_9	644966.Tmar_0414	2.551e-30	129.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5469887_10	1244869.H261_16840	6.232e-27	121.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2TSN7@28211|Alphaproteobacteria,2JPCS@204441|Rhodospirillales	204441|Rhodospirillales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
ZZS2_k127_5469887_18	1380394.JADL01000008_gene3597	0.0007533	52.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2UDGR@28211|Alphaproteobacteria,2JTNP@204441|Rhodospirillales	204441|Rhodospirillales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
ZZS2_k127_5469887_6	713586.KB900536_gene398	1.955e-41	166.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1S0WJ@1236|Gammaproteobacteria,1WWFB@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
ZZS2_k127_5469887_5	269796.Rru_A2909	7.439e-68	239.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2JQ9E@204441|Rhodospirillales	204441|Rhodospirillales	Q	ABC transporter, ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS2_k127_5469887_16	935848.JAEN01000001_gene3435	8.077e-08	66.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2PVM2@265|Paracoccus	28211|Alphaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS2_k127_5469887_17	243365.CV_2546	0.0001022	55.0	COG3009@1|root,COG3009@2|Bacteria,1PUXI@1224|Proteobacteria,2WAZH@28216|Betaproteobacteria,2KTEK@206351|Neisseriales	206351|Neisseriales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
ZZS2_k127_5469887_13	575540.Isop_3410	1.134e-17	97.0	COG0227@1|root,COG0227@2|Bacteria,2J0SS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
ZZS2_k127_5469887_15	1201293.AKXQ01000006_gene217	7.676e-11	72.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1T2G8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
ZZS2_k127_5469887_4	1267535.KB906767_gene4061	1.036e-111	386.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_5469887_11	240016.ABIZ01000001_gene5821	3.474e-22	113.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42,Glyco_hydro_42M
ZZS2_k127_5469887_12	1123393.KB891316_gene1181	2.355e-18	101.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,1KSU6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
ZZS2_k127_5520566_1	880073.Calab_2039	3.499e-61	227.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
ZZS2_k127_5520566_4	502558.EGYY_09690	1.84e-08	60.0	COG1872@1|root,COG1872@2|Bacteria,2HWHC@201174|Actinobacteria,4CYDE@84998|Coriobacteriia	84998|Coriobacteriia	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
ZZS2_k127_5520566_2	756272.Plabr_2560	2.932e-59	234.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_5520566_3	1121468.AUBR01000008_gene2045	6.961e-50	196.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42F58@68295|Thermoanaerobacterales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
ZZS2_k127_5520566_0	794903.OPIT5_07360	2.445e-94	317.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS2_k127_556280_0	935845.JADQ01000029_gene1230	9.379e-126	429.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
ZZS2_k127_556280_3	1303518.CCALI_02109	6.943e-08	66.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_556280_2	55207.KP22_12470	6.984e-25	120.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1MR9J@122277|Pectobacterium	1236|Gammaproteobacteria	NU	General secretion pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_556280_1	429009.Adeg_0173	1.15e-73	272.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_5612073_2	1232410.KI421415_gene2974	1.933e-116	415.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
ZZS2_k127_5612073_0	1121918.ARWE01000001_gene3016	1.603e-179	576.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
ZZS2_k127_5612073_6	251221.35214694	8.72e-42	177.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
ZZS2_k127_5612073_8	404589.Anae109_4396	3.355e-05	56.0	COG2267@1|root,COG2267@2|Bacteria,1PXRQ@1224|Proteobacteria,434SS@68525|delta/epsilon subdivisions,2X90B@28221|Deltaproteobacteria,2Z19P@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS2_k127_5612073_5	391625.PPSIR1_08007	2.283e-96	323.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2Z0ES@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS2_k127_5612073_3	211114.JOEF01000019_gene530	4.692e-110	388.0	COG1404@1|root,COG1404@2|Bacteria,2I9U6@201174|Actinobacteria,4E1MY@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
ZZS2_k127_5612073_1	381666.H16_A0479	1.299e-135	480.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,1K06B@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
ZZS2_k127_5612073_7	485913.Krac_9911	1.725e-13	85.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Gram_pos_anchor
ZZS2_k127_5612073_4	1121957.ATVL01000014_gene1459	7.268e-97	336.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5616784_5	1041159.AZUW01000009_gene4548	1.348e-132	453.0	COG2304@1|root,COG2304@2|Bacteria,1R7H7@1224|Proteobacteria	1224|Proteobacteria	O	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64,VWA,VWA_2
ZZS2_k127_5616784_19	653045.Strvi_1547	8.136e-07	62.0	COG3468@1|root,COG3468@2|Bacteria,2IKH3@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
ZZS2_k127_5616784_1	760192.Halhy_4981	1.922e-301	940.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,1IR1K@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS2_k127_5616784_8	1317122.ATO12_08525	4.582e-83	282.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia,2YJ2H@290174|Aquimarina	976|Bacteroidetes	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
ZZS2_k127_5616784_7	1123024.AUII01000011_gene4469	1.731e-93	323.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4E0XN@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
ZZS2_k127_5616784_15	163908.KB235896_gene262	1.099e-16	92.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,1G2VV@1117|Cyanobacteria,1HQES@1161|Nostocales	1117|Cyanobacteria	Q	Laminin G domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_5616784_13	1123242.JH636436_gene225	1.194e-21	108.0	COG4219@1|root,COG4219@2|Bacteria,2J24Z@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
ZZS2_k127_5616784_11	234267.Acid_0851	9.032e-48	194.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
ZZS2_k127_5616784_18	1497679.EP56_18010	2.727e-07	64.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,26K4C@186820|Listeriaceae	91061|Bacilli	O	glycoprotease	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
ZZS2_k127_5616784_6	234267.Acid_1911	2.387e-95	334.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS2_k127_5616784_10	237368.SCABRO_00955	8.722e-53	209.0	COG1624@1|root,COG1624@2|Bacteria,2IZSP@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
ZZS2_k127_5616784_4	882.DVU_1278	3.393e-181	594.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2M88M@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
ZZS2_k127_5616784_20	1521187.JPIM01000144_gene3346	0.0004981	44.0	COG4636@1|root,COG4636@2|Bacteria,2G98P@200795|Chloroflexi,3772T@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_5616784_17	760568.Desku_0493	3.762e-10	72.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5616784_2	1122603.ATVI01000005_gene3218	1.927e-221	709.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RPJW@1236|Gammaproteobacteria,1X39K@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_5616784_9	765420.OSCT_0910	3.454e-64	246.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
ZZS2_k127_5616784_16	754035.Mesau_00139	1.266e-11	79.0	2E4CR@1|root,32Z86@2|Bacteria,1N7UZ@1224|Proteobacteria,2UF9N@28211|Alphaproteobacteria,43M25@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	NADH-dependant formate dehydrogenase delta subunit FdsD	fdsD	-	1.17.1.9	ko:K00126	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	FdsD
ZZS2_k127_5616784_0	1283300.ATXB01000001_gene1024	0.0	1501.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XEFY@135618|Methylococcales	135618|Methylococcales	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
ZZS2_k127_5616784_3	1283300.ATXB01000001_gene1025	1.421e-183	579.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XEDW@135618|Methylococcales	135618|Methylococcales	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
ZZS2_k127_5683658_11	665959.HMPREF1013_04736	4.11e-05	52.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_5683658_10	926561.KB900619_gene2541	4.992e-08	58.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,3WAUZ@53433|Halanaerobiales	186801|Clostridia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
ZZS2_k127_5683658_9	880073.Calab_3509	3.531e-08	67.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,COesterase,Esterase,Peptidase_S9
ZZS2_k127_5683658_6	530564.Psta_2698	6.061e-26	124.0	COG1413@1|root,COG1520@1|root,COG1729@1|root,COG1413@2|Bacteria,COG1520@2|Bacteria,COG1729@2|Bacteria,2J3VN@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_5683658_2	1121957.ATVL01000014_gene1459	1.19e-104	372.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5683658_1	1123073.KB899243_gene814	1.795e-113	374.0	COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,1S5SD@1236|Gammaproteobacteria,1X617@135614|Xanthomonadales	135614|Xanthomonadales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
ZZS2_k127_5683658_7	404380.Gbem_2585	2.241e-15	90.0	COG3014@1|root,COG3014@2|Bacteria,1RAHY@1224|Proteobacteria,43CAG@68525|delta/epsilon subdivisions,2X7KZ@28221|Deltaproteobacteria,43SFY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5683658_5	1303518.CCALI_01218	1.787e-26	128.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA,PMT_2
ZZS2_k127_5683658_4	583355.Caka_2738	1.006e-31	141.0	28IAE@1|root,2Z8D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5683658_8	1118235.CAJH01000033_gene2159	6.8e-11	71.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1T178@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
ZZS2_k127_5683658_3	903818.KI912268_gene2220	2.973e-75	256.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
ZZS2_k127_5683658_0	1121920.AUAU01000005_gene1080	3.978e-246	781.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
ZZS2_k127_5707908_4	74547.PMT_2135	1.998e-86	302.0	COG1364@1|root,COG1364@2|Bacteria,1G1H7@1117|Cyanobacteria,1MKQA@1212|Prochloraceae	1117|Cyanobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argJ	ArgJ
ZZS2_k127_5707908_13	502025.Hoch_4583	5.806e-42	166.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria,2Z31F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
ZZS2_k127_5707908_18	357808.RoseRS_4233	5.944e-16	90.0	COG0438@1|root,COG0438@2|Bacteria,2G6JX@200795|Chloroflexi,376GP@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
ZZS2_k127_5707908_2	1131269.AQVV01000013_gene1726	2.405e-112	381.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
ZZS2_k127_5707908_21	1142394.PSMK_15110	1.068e-05	58.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
ZZS2_k127_5707908_14	1463861.JNXE01000004_gene1941	1.146e-39	164.0	COG0520@1|root,COG0665@1|root,COG0520@2|Bacteria,COG0665@2|Bacteria,2H9MG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily	egtE	GO:0000096,GO:0000097,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.4.1.36	ko:K18913	ko00340,map00340	-	R11023	RC01784,RC03328	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,DAO
ZZS2_k127_5707908_1	247490.KSU1_B0239	2.267e-124	415.0	COG1160@1|root,COG1160@2|Bacteria,2IWXY@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
ZZS2_k127_5707908_12	743721.Psesu_2242	3.002e-49	188.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1X37Y@135614|Xanthomonadales	135614|Xanthomonadales	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
ZZS2_k127_5707908_7	1207063.P24_18586	7.075e-58	210.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,2JRXQ@204441|Rhodospirillales	204441|Rhodospirillales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS2_k127_5707908_20	264198.Reut_A2131	2.869e-12	72.0	2AGC9@1|root,316HY@2|Bacteria,1PXMI@1224|Proteobacteria,2WD0V@28216|Betaproteobacteria,1K8YX@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5707908_3	1123508.JH636442_gene3952	6.139e-109	392.0	COG0323@1|root,COG0323@2|Bacteria,2IXI2@203682|Planctomycetes	203682|Planctomycetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ZZS2_k127_5707908_23	1283299.AUKG01000004_gene1237	0.0002333	54.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
ZZS2_k127_5707908_6	886293.Sinac_1699	2.568e-60	228.0	COG0382@1|root,COG0382@2|Bacteria,2IX4Z@203682|Planctomycetes	203682|Planctomycetes	H	COG0382 4-hydroxybenzoate polyprenyltransferase and related	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
ZZS2_k127_5707908_11	1120973.AQXL01000134_gene1529	8.604e-52	200.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,2789X@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ZZS2_k127_5707908_17	502025.Hoch_4674	6.605e-19	96.0	COG1266@1|root,COG1266@2|Bacteria,1QAGW@1224|Proteobacteria,43E11@68525|delta/epsilon subdivisions,2WZDX@28221|Deltaproteobacteria,2Z1XB@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
ZZS2_k127_5707908_10	243090.RB2752	6.367e-53	194.0	COG0500@1|root,COG2226@2|Bacteria,2IYWE@203682|Planctomycetes	203682|Planctomycetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
ZZS2_k127_5707908_22	1123322.KB904677_gene3136	0.0001578	55.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
ZZS2_k127_5707908_0	316067.Geob_0336	6.411e-129	437.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,4378Y@68525|delta/epsilon subdivisions,2X2C1@28221|Deltaproteobacteria,43UD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS2_k127_5707908_15	1123242.JH636435_gene2728	4.111e-29	135.0	COG0272@1|root,COG0457@1|root,COG0789@1|root,COG0272@2|Bacteria,COG0457@2|Bacteria,COG0789@2|Bacteria,2IZBY@203682|Planctomycetes	203682|Planctomycetes	K	O-linked GlcNAc transferase	-	-	-	-	-	-	-	-	-	-	-	-	BRCT,MerR_1,TPR_16
ZZS2_k127_5707908_9	882086.SacxiDRAFT_2597	7.348e-55	212.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4DXG0@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase D DNA polymerase LigD	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS2_k127_5707908_8	1123242.JH636435_gene1762	7.231e-55	204.0	COG1273@1|root,COG1273@2|Bacteria,2J4I3@203682|Planctomycetes	203682|Planctomycetes	S	Ku70/Ku80 beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Ku
ZZS2_k127_5707908_5	443143.GM18_0267	6.54e-61	220.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS2_k127_5707908_19	1453500.AT05_05250	1.145e-15	91.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CHU_C,PKD,Peptidase_S8,fn3
ZZS2_k127_5707908_16	755732.Fluta_2488	1.445e-23	112.0	COG4733@1|root,COG4935@1|root,COG4733@2|Bacteria,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5719182_1	626887.J057_12606	4.495e-42	166.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5719182_2	626887.J057_12606	2.892e-41	164.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5719182_3	1313304.CALK_0765	4.375e-29	124.0	COG4399@1|root,COG4399@2|Bacteria	2|Bacteria	-	-	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
ZZS2_k127_5719182_4	1379698.RBG1_1C00001G1241	3.377e-26	123.0	COG0613@1|root,COG0613@2|Bacteria,2NPWD@2323|unclassified Bacteria	2|Bacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
ZZS2_k127_5719182_0	555079.Toce_1677	2.147e-97	329.0	COG3938@1|root,COG3938@2|Bacteria,1TQ61@1239|Firmicutes,2487S@186801|Clostridia,42HT1@68295|Thermoanaerobacterales	186801|Clostridia	G	Proline racemase	prdF	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
ZZS2_k127_5719409_6	483219.LILAB_30070	1.951e-05	58.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_5719409_5	445972.ANACOL_01380	1.934e-11	68.0	2E8Y4@1|root,3337V@2|Bacteria,1VAY7@1239|Firmicutes,24JV5@186801|Clostridia,3WPX7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5719409_0	468059.AUHA01000002_gene1280	2.914e-97	333.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,1J054@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
ZZS2_k127_5719409_3	1499967.BAYZ01000019_gene6321	2.817e-28	119.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	MIase
ZZS2_k127_5719409_1	448385.sce8527	3.407e-89	301.0	2A70U@1|root,30VW1@2|Bacteria,1RGBZ@1224|Proteobacteria,42VYK@68525|delta/epsilon subdivisions,2WSFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
ZZS2_k127_5719409_2	1396418.BATQ01000032_gene5682	3.083e-35	139.0	2C8BR@1|root,2ZH6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5724971_0	379066.GAU_2646	1.05e-213	699.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS2_k127_5724971_5	765177.Desmu_1233	3.919e-54	218.0	COG0024@1|root,arCOG01001@2157|Archaea,2XPVJ@28889|Crenarchaeota	28889|Crenarchaeota	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
ZZS2_k127_5724971_1	502025.Hoch_6614	2.284e-164	525.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YU40@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_5724971_4	997346.HMPREF9374_0645	1.887e-73	260.0	COG1063@1|root,COG1063@2|Bacteria,1UI0K@1239|Firmicutes,4IUD0@91061|Bacilli,27D28@186824|Thermoactinomycetaceae	91061|Bacilli	C	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_5724971_8	204669.Acid345_3253	9.208e-41	157.0	COG1607@1|root,COG1607@2|Bacteria,3Y53T@57723|Acidobacteria,2JMAX@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS2_k127_5724971_21	886293.Sinac_7101	0.0009348	52.0	COG4219@1|root,COG4219@2|Bacteria,2J1Q3@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
ZZS2_k127_5724971_17	356851.JOAN01000004_gene1164	2.882e-05	58.0	COG4932@1|root,COG4932@2|Bacteria,2IFXI@201174|Actinobacteria,4DCX4@85008|Micromonosporales	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_5724971_15	1210884.HG799466_gene12889	4.186e-06	61.0	COG1595@1|root,COG1595@2|Bacteria,2J16J@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5724971_6	1142394.PSMK_27540	3.345e-51	190.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_5724971_14	272559.BF9343_1113	1.033e-07	61.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,4AKZF@815|Bacteroidaceae	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS2_k127_5724971_3	671143.DAMO_0390	2.25e-101	345.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
ZZS2_k127_5724971_7	886293.Sinac_0140	1.164e-42	168.0	2EGZK@1|root,33ARQ@2|Bacteria,2J4A7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5724971_10	861299.J421_1282	6.193e-15	82.0	COG2911@1|root,COG3209@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,CHU_C,Calx-beta,DUF4347,HemolysinCabind,PATR
ZZS2_k127_5724971_20	1144275.COCOR_01518	0.000429	55.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_5724971_18	1410632.JHWW01000023_gene38	0.0001026	55.0	COG2206@1|root,COG3292@1|root,COG2206@2|Bacteria,COG3292@2|Bacteria,1UM1T@1239|Firmicutes,25222@186801|Clostridia,27UKY@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Reg_prop,Y_Y_Y
ZZS2_k127_5724971_11	313612.L8106_09571	1.838e-14	88.0	COG3011@1|root,COG3011@2|Bacteria,1GBBP@1117|Cyanobacteria,1HDV0@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
ZZS2_k127_5724971_19	1303518.CCALI_00760	0.0001922	54.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,COesterase,Esterase,Peptidase_S9
ZZS2_k127_5724971_2	1254432.SCE1572_40310	6.979e-161	521.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,430DD@68525|delta/epsilon subdivisions,2WVKB@28221|Deltaproteobacteria,2YUBR@29|Myxococcales	28221|Deltaproteobacteria	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	ligB	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
ZZS2_k127_5724971_12	631362.Thi970DRAFT_02178	1.378e-12	72.0	2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria,1SUYT@1236|Gammaproteobacteria,1X1Y1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5724971_16	1120960.ATXG01000015_gene1611	2.636e-05	55.0	2DRBI@1|root,33B4D@2|Bacteria,2GQYN@201174|Actinobacteria,4FQ3K@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5724971_9	1379698.RBG1_1C00001G0328	1.176e-20	94.0	2C7E0@1|root,330TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5739637_13	649639.Bcell_1517	1.181e-45	173.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus	91061|Bacilli	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS2_k127_5739637_31	1128421.JAGA01000003_gene2714	6.02e-15	85.0	COG4848@1|root,COG4848@2|Bacteria	2|Bacteria	L	Belongs to the UPF0354 family	ytpQ	-	-	-	-	-	-	-	-	-	-	-	DUF1444
ZZS2_k127_5739637_38	483219.LILAB_18935	2.152e-07	65.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K13735,ko:K18491,ko:K20276	ko02024,ko04550,ko05100,map02024,map04550,map05100	-	-	-	ko00000,ko00001,ko03000	-	-	-	CarboxypepD_reg,PDZ_2
ZZS2_k127_5739637_30	1254432.SCE1572_34065	2.559e-15	85.0	COG1600@1|root,COG1600@2|Bacteria,1R9XX@1224|Proteobacteria	1224|Proteobacteria	C	COG1145 Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5739637_11	326427.Cagg_0112	3.212e-47	180.0	COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi,375F3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
ZZS2_k127_5739637_36	1121106.JQKB01000010_gene436	1.416e-08	62.0	COG0599@1|root,COG0599@2|Bacteria,1RHZ1@1224|Proteobacteria	1224|Proteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
ZZS2_k127_5739637_26	268407.PWYN_11050	9.905e-18	95.0	COG0627@1|root,COG0627@2|Bacteria,1V7KC@1239|Firmicutes,4HT81@91061|Bacilli,26V80@186822|Paenibacillaceae	91061|Bacilli	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_5739637_14	869210.Marky_0288	5.978e-44	178.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
ZZS2_k127_5739637_33	886293.Sinac_3151	1.078e-11	72.0	2DQ4A@1|root,334NN@2|Bacteria,2J0NK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
ZZS2_k127_5739637_20	1521187.JPIM01000051_gene3479	4.892e-41	169.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi,375B8@32061|Chloroflexia	32061|Chloroflexia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
ZZS2_k127_5739637_2	1210884.HG799465_gene11914	8.781e-95	323.0	COG0008@1|root,COG0008@2|Bacteria,2IYG3@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ZZS2_k127_5739637_35	33898.JRHJ01000004_gene2202	4.361e-09	70.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM,Pkinase
ZZS2_k127_5739637_6	640511.BC1002_6887	1.708e-61	230.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2VKXT@28216|Betaproteobacteria,1KGPU@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	nifA	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
ZZS2_k127_5739637_34	1028800.RG540_PA09350	2.258e-09	64.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,4B8MB@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	dctD	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_5739637_18	1242864.D187_003905	4.171e-42	164.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42R3K@68525|delta/epsilon subdivisions,2WJNA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
ZZS2_k127_5739637_8	1173025.GEI7407_0746	9.684e-60	221.0	COG1409@1|root,COG1409@2|Bacteria,1G1Z6@1117|Cyanobacteria,1H9FX@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ZZS2_k127_5739637_1	1392489.JPOL01000002_gene2894	1.276e-99	356.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia,2XK9D@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
ZZS2_k127_5739637_7	340.xcc-b100_4469	3.893e-60	224.0	COG0665@1|root,COG0665@2|Bacteria,1PTX6@1224|Proteobacteria,1RY49@1236|Gammaproteobacteria,1X56R@135614|Xanthomonadales	135614|Xanthomonadales	E	D-amino acid	-	-	-	ko:K21061	ko00330,map00330	-	R11428	RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS2_k127_5739637_32	420324.KI912034_gene2650	3.363e-14	86.0	COG1034@1|root,COG1034@2|Bacteria,1QYIY@1224|Proteobacteria	1224|Proteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
ZZS2_k127_5739637_4	1463887.KL590042_gene4282	1.592e-76	275.0	COG0446@1|root,COG0446@2|Bacteria,2GJM6@201174|Actinobacteria	201174|Actinobacteria	E	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
ZZS2_k127_5739637_0	580332.Slit_0121	4.421e-120	391.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
ZZS2_k127_5739637_28	945713.IALB_1835	6.929e-16	90.0	COG2911@1|root,COG4935@1|root,COG2911@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,FlgD_ig,Kelch_4,PA,Peptidase_M36
ZZS2_k127_5739637_27	945713.IALB_1835	6.751e-16	89.0	COG2911@1|root,COG4935@1|root,COG2911@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,FlgD_ig,Kelch_4,PA,Peptidase_M36
ZZS2_k127_5739637_3	1121472.AQWN01000001_gene190	9.366e-93	312.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,260FR@186807|Peptococcaceae	186801|Clostridia	E	PFAM DAHP synthetase I	aroF1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ZZS2_k127_5739637_5	858215.Thexy_0816	1.414e-64	235.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,42FAI@68295|Thermoanaerobacterales	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
ZZS2_k127_5739637_39	1192034.CAP_5779	1.479e-05	50.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2YVR1@29|Myxococcales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
ZZS2_k127_5739637_15	290397.Adeh_2607	5.996e-43	168.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
ZZS2_k127_5739637_12	1121864.OMO_01563	6.295e-47	175.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,4AZ94@81852|Enterococcaceae	91061|Bacilli	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15680	Guanylate_kin
ZZS2_k127_5739637_19	519989.ECTPHS_08708	6.032e-42	168.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
ZZS2_k127_5739637_29	292415.Tbd_0180	1.002e-15	90.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,1KRXW@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
ZZS2_k127_5739637_24	472759.Nhal_3554	7.246e-29	128.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1WYUS@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
ZZS2_k127_5739637_40	66377.JOBH01000003_gene5250	0.0001549	52.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,2GNKQ@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
ZZS2_k127_5739637_9	179408.Osc7112_4905	8.928e-54	209.0	COG0500@1|root,COG2226@2|Bacteria,1GQXS@1117|Cyanobacteria,1HI4R@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_5739637_10	383372.Rcas_3636	7.444e-53	206.0	COG1215@1|root,COG1215@2|Bacteria,2G9DX@200795|Chloroflexi,377P0@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_5739637_22	1336249.JADW01000009_gene1560	2.369e-39	164.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U3N3@28211|Alphaproteobacteria,4B738@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5739637_25	1396418.BATQ01000014_gene4346	8.462e-18	99.0	COG1216@1|root,COG5309@1|root,COG1216@2|Bacteria,COG5309@2|Bacteria,46SAC@74201|Verrucomicrobia,2IV7T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_5739637_23	240016.ABIZ01000001_gene310	1.399e-34	141.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
ZZS2_k127_5739637_37	1123257.AUFV01000002_gene2374	3.706e-08	66.0	COG3562@1|root,COG3562@2|Bacteria,1QBTU@1224|Proteobacteria,1T7E3@1236|Gammaproteobacteria,1X95T@135614|Xanthomonadales	135614|Xanthomonadales	M	Capsule polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Capsule_synth
ZZS2_k127_5739637_21	251221.35212829	3.777e-40	166.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	CBM9_1,CBM_6
ZZS2_k127_5749447_12	340.xcc-b100_1239	4.125e-14	76.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1X33I@135614|Xanthomonadales	135614|Xanthomonadales	E	asparaginase	aga	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2,TAT_signal
ZZS2_k127_5749447_1	68219.JNXI01000054_gene182	8.569e-140	482.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
ZZS2_k127_5749447_13	1245469.S58_36300	3.154e-12	81.0	28VS2@1|root,2ZHTX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5749447_5	886293.Sinac_4157	1.008e-44	173.0	COG4233@1|root,COG4233@2|Bacteria,2J49W@203682|Planctomycetes	203682|Planctomycetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
ZZS2_k127_5749447_4	1123242.JH636435_gene1022	3.81e-64	237.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
ZZS2_k127_5749447_7	886293.Sinac_1932	1.624e-37	162.0	COG2706@1|root,COG2706@2|Bacteria,2J55E@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_5749447_17	886293.Sinac_4157	7.829e-05	52.0	COG4233@1|root,COG4233@2|Bacteria,2J49W@203682|Planctomycetes	203682|Planctomycetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
ZZS2_k127_5749447_16	709991.Odosp_3404	2.251e-06	60.0	COG4232@1|root,COG4232@2|Bacteria,4NH5B@976|Bacteroidetes,2FWD6@200643|Bacteroidia,22ZJ9@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
ZZS2_k127_5749447_0	1168065.DOK_13169	8.037e-184	592.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,1RR9Q@1236|Gammaproteobacteria,1J7M1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Pfam:DUF1446	atuA	-	-	-	-	-	-	-	-	-	-	-	AtuA
ZZS2_k127_5749447_10	1168065.DOK_00420	2.039e-25	123.0	2CIU6@1|root,32S8H@2|Bacteria,1MZTN@1224|Proteobacteria,1S6TT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5749447_3	1121920.AUAU01000002_gene2003	1.124e-74	261.0	COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria	57723|Acidobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
ZZS2_k127_5749447_2	595460.RRSWK_02998	8.168e-98	333.0	COG0012@1|root,COG0012@2|Bacteria,2IY8K@203682|Planctomycetes	203682|Planctomycetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
ZZS2_k127_5749447_18	485917.Phep_2353	0.0001028	47.0	COG0526@1|root,COG0526@2|Bacteria,4P759@976|Bacteroidetes	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5749447_9	404589.Anae109_4174	1.571e-25	124.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
ZZS2_k127_5749447_6	886293.Sinac_6489	1.451e-42	175.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
ZZS2_k127_5749447_15	1046724.KB889827_gene2616	3.197e-07	60.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_5749447_8	401053.AciPR4_3251	7.933e-37	151.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS2_k127_5749447_11	518766.Rmar_2731	1.611e-15	87.0	COG1917@1|root,COG1917@2|Bacteria,4P9GY@976|Bacteroidetes,1FKCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS2_k127_5757948_1	748280.NH8B_3525	1.123e-88	304.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,2KPCW@206351|Neisseriales	206351|Neisseriales	O	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
ZZS2_k127_5757948_4	880072.Desac_0423	2.936e-27	113.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,42VMA@68525|delta/epsilon subdivisions,2WS3K@28221|Deltaproteobacteria,2MS7F@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
ZZS2_k127_5757948_6	65393.PCC7424_5049	1.984e-10	67.0	2C6B2@1|root,335GA@2|Bacteria,1GRBH@1117|Cyanobacteria,3KKV9@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5757948_7	326427.Cagg_1235	6.731e-10	72.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5757948_0	502025.Hoch_5321	1.252e-103	356.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43A4R@68525|delta/epsilon subdivisions,2X23J@28221|Deltaproteobacteria,2YUTA@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
ZZS2_k127_5757948_5	1123354.AUDR01000012_gene1918	8.946e-24	113.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,1KRTC@119069|Hydrogenophilales	119069|Hydrogenophilales	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
ZZS2_k127_5757948_2	886293.Sinac_0799	7.47e-60	215.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
ZZS2_k127_5757948_3	756499.Desde_3081	2.188e-41	175.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,261DN@186807|Peptococcaceae	186801|Clostridia	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS2_k127_5759095_6	518766.Rmar_1550	2.735e-57	203.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	paaA	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS2_k127_5759095_0	391625.PPSIR1_25066	7.842e-89	309.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
ZZS2_k127_5759095_8	1123508.JH636448_gene7570	3.773e-23	106.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
ZZS2_k127_5759095_7	886293.Sinac_1394	5.403e-33	148.0	COG4219@1|root,COG4219@2|Bacteria,2IZRJ@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
ZZS2_k127_5759095_1	765420.OSCT_1523	9.009e-88	297.0	COG0384@1|root,COG0384@2|Bacteria,2G7XR@200795|Chloroflexi,377M3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
ZZS2_k127_5759095_2	378806.STAUR_8351	4.004e-72	254.0	COG2253@1|root,COG2253@2|Bacteria,1QRWZ@1224|Proteobacteria,42WWC@68525|delta/epsilon subdivisions,2WSPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
ZZS2_k127_5759095_4	378806.STAUR_8352	1.987e-59	213.0	28KYY@1|root,2ZAEA@2|Bacteria,1RB7S@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5759095_5	290397.Adeh_0738	4.407e-59	226.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS2_k127_5759095_3	391625.PPSIR1_08881	8.953e-70	246.0	COG0121@1|root,COG0121@2|Bacteria	2|Bacteria	S	cellular modified histidine biosynthetic process	egtC	-	-	ko:K18802	-	-	-	-	ko00000	-	-	-	GATase_4
ZZS2_k127_5759095_10	395495.Lcho_3739	3.008e-06	61.0	COG0689@1|root,COG5276@1|root,COG0689@2|Bacteria,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
ZZS2_k127_5759095_11	744979.R2A130_3115	3.308e-05	57.0	COG1404@1|root,COG3210@1|root,COG4386@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4386@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
ZZS2_k127_5759095_9	234267.Acid_2602	1.827e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,3Y893@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5795976_29	102125.Xen7305DRAFT_00046010	5.055e-14	87.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G0DF@1117|Cyanobacteria,3VM5A@52604|Pleurocapsales	1117|Cyanobacteria	OQ	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Peptidase_S8
ZZS2_k127_5795976_14	521674.Plim_1954	3.994e-51	192.0	COG0424@1|root,COG0424@2|Bacteria,2IZQQ@203682|Planctomycetes	203682|Planctomycetes	D	TIGRFAM maf protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
ZZS2_k127_5795976_10	1254432.SCE1572_02640	6.015e-74	263.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2WNI2@28221|Deltaproteobacteria,2YU7J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
ZZS2_k127_5795976_2	867845.KI911784_gene1198	4.589e-123	420.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,37630@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_5795976_4	658086.HMPREF0994_04444	4.667e-95	334.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27IP5@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
ZZS2_k127_5795976_33	344747.PM8797T_01634	0.0008077	46.0	COG1758@1|root,COG1758@2|Bacteria,2J0KS@203682|Planctomycetes	203682|Planctomycetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
ZZS2_k127_5795976_7	935948.KE386494_gene372	3.661e-82	295.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,42FE6@68295|Thermoanaerobacterales	186801|Clostridia	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
ZZS2_k127_5795976_24	1144275.COCOR_01151	2.143e-21	104.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
ZZS2_k127_5795976_1	575540.Isop_1103	1.899e-202	651.0	COG3808@1|root,COG3808@2|Bacteria,2IXUH@203682|Planctomycetes	203682|Planctomycetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K01507,ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
ZZS2_k127_5795976_21	557598.LHK_00349	3.123e-27	121.0	COG0586@1|root,COG0586@2|Bacteria,1R6V4@1224|Proteobacteria,2VMXP@28216|Betaproteobacteria,2KQ67@206351|Neisseriales	206351|Neisseriales	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS2_k127_5795976_16	886293.Sinac_6555	1.374e-43	171.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_5795976_26	426716.JOAJ01000010_gene6244	4.956e-15	85.0	COG1716@1|root,COG3629@1|root,COG1716@2|Bacteria,COG3629@2|Bacteria,2HEQI@201174|Actinobacteria,4FVV3@85025|Nocardiaceae	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,FHA,Trans_reg_C,Yop-YscD_cpl
ZZS2_k127_5795976_13	1185876.BN8_02230	2.517e-51	197.0	COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,47RDA@768503|Cytophagia	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
ZZS2_k127_5795976_23	1183438.GKIL_4082	2.429e-22	113.0	COG0438@1|root,COG0438@2|Bacteria,1GD7K@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5795976_11	1382356.JQMP01000003_gene2572	4.077e-54	214.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,27Y1R@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_5795976_8	292459.STH1116	5.853e-75	273.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,24DGJ@186801|Clostridia	186801|Clostridia	S	SMART metal-dependent phosphohydrolase, HD	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
ZZS2_k127_5795976_9	391625.PPSIR1_11943	8.675e-75	277.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
ZZS2_k127_5795976_6	269084.syc1565_c	2.34e-84	295.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,1GZPF@1129|Synechococcus	1117|Cyanobacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_5795976_25	330214.NIDE0685	4.855e-16	89.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679,ko:K08084	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH
ZZS2_k127_5795976_20	1121430.JMLG01000036_gene159	4.366e-33	147.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
ZZS2_k127_5795976_0	234267.Acid_1182	2.528e-208	660.0	COG0076@1|root,COG0076@2|Bacteria,3Y2SW@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
ZZS2_k127_5795976_27	330214.NIDE0521	8.242e-15	87.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
ZZS2_k127_5795976_12	357808.RoseRS_4114	2.464e-52	202.0	COG3356@1|root,COG3356@2|Bacteria,2G7ZP@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5795976_17	1499967.BAYZ01000194_gene3127	1.868e-40	160.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
ZZS2_k127_5795976_31	203275.BFO_2314	1.764e-08	61.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
ZZS2_k127_5795976_5	448385.sce5399	4.764e-87	309.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YWRH@29|Myxococcales	28221|Deltaproteobacteria	L	OB-fold nucleic acid binding domain	-	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
ZZS2_k127_5795976_19	1125863.JAFN01000001_gene1584	3.254e-33	136.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS2_k127_5795976_22	696369.KI912183_gene1616	1.126e-24	109.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,262C4@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ZZS2_k127_5795976_32	497964.CfE428DRAFT_0261	0.0006591	45.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS2_k127_5795976_3	324602.Caur_1178	1.589e-114	379.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,374U8@32061|Chloroflexia	32061|Chloroflexia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
ZZS2_k127_5795976_18	1128421.JAGA01000003_gene3186	4.167e-39	161.0	COG0568@1|root,COG0568@2|Bacteria,2NQNT@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_5795976_15	398767.Glov_3474	1.279e-50	189.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42QTI@68525|delta/epsilon subdivisions,2WMRH@28221|Deltaproteobacteria,43SYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
ZZS2_k127_585304_19	497321.C664_20163	0.0004386	50.0	COG3436@1|root,COG3436@2|Bacteria,1MYAC@1224|Proteobacteria,2VMF3@28216|Betaproteobacteria,2KXTT@206389|Rhodocyclales	206389|Rhodocyclales	L	COG3436 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
ZZS2_k127_585304_12	498761.HM1_1938	8.367e-24	112.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
ZZS2_k127_585304_2	648757.Rvan_2307	9.75e-175	580.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria,3N7MR@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS2_k127_585304_5	243231.GSU1204	1.157e-121	414.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,43T1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
ZZS2_k127_585304_6	446465.Bfae_06470	7.319e-120	396.0	COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria,4FBHV@85020|Dermabacteraceae	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_585304_8	1125863.JAFN01000001_gene2804	6.65e-82	294.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
ZZS2_k127_585304_9	404589.Anae109_3929	3.846e-42	161.0	COG5637@1|root,COG5637@2|Bacteria,1PJX4@1224|Proteobacteria,435GH@68525|delta/epsilon subdivisions,2WZU0@28221|Deltaproteobacteria,2Z2R9@29|Myxococcales	28221|Deltaproteobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_585304_16	653733.Selin_0183	1.961e-14	86.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
ZZS2_k127_585304_15	1128421.JAGA01000002_gene1841	1.775e-14	88.0	COG3429@1|root,COG3429@2|Bacteria	2|Bacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem,PG_binding_1
ZZS2_k127_585304_1	479434.Sthe_2436	3.608e-181	584.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
ZZS2_k127_585304_13	794903.OPIT5_23175	3.662e-15	90.0	COG3278@1|root,COG3278@2|Bacteria,46XVS@74201|Verrucomicrobia,3K8EN@414999|Opitutae	414999|Opitutae	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_585304_4	1192034.CAP_1588	1.271e-127	418.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2YTVB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
ZZS2_k127_585304_17	985255.APHJ01000019_gene630	1.134e-11	76.0	COG3021@1|root,COG3021@2|Bacteria,4NPZ4@976|Bacteroidetes,1I2G7@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_585304_0	314230.DSM3645_30206	1.25e-286	906.0	COG0550@1|root,COG0550@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
ZZS2_k127_585304_7	1288963.ADIS_2286	2.126e-93	325.0	COG4804@1|root,COG4804@2|Bacteria,4NGY8@976|Bacteroidetes,47N9S@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
ZZS2_k127_585304_10	204669.Acid345_0246	3.09e-38	150.0	COG5649@1|root,COG5649@2|Bacteria,3Y94P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_585304_14	742765.HMPREF9457_02246	5.22e-15	78.0	2E6K5@1|root,3316X@2|Bacteria,1VGNS@1239|Firmicutes,254JZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_585304_18	497965.Cyan7822_4658	0.0003961	46.0	2E0F1@1|root,32W1E@2|Bacteria,1G6H6@1117|Cyanobacteria,3KJYV@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_585304_3	1123242.JH636435_gene2097	1.716e-156	514.0	COG0515@1|root,COG0515@2|Bacteria,2IY73@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_585304_11	1123242.JH636435_gene2096	7.446e-37	161.0	COG1595@1|root,COG1595@2|Bacteria,2IZMI@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_5873047_0	926560.KE387023_gene2937	2.78e-100	338.0	COG2326@1|root,COG2326@2|Bacteria,1WKEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
ZZS2_k127_5873047_2	216432.CA2559_01455	7.885e-10	71.0	COG0747@1|root,COG1404@1|root,COG2866@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG0747@2|Bacteria,COG1404@2|Bacteria,COG2866@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
ZZS2_k127_5873047_1	402881.Plav_2485	2.774e-15	79.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,1JNCZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	DEAD-like helicases superfamily	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
ZZS2_k127_5880450_3	1386089.N865_05090	1.076e-23	110.0	COG2304@1|root,COG2304@2|Bacteria,2GKDC@201174|Actinobacteria,4FI9T@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
ZZS2_k127_5880450_2	404589.Anae109_0580	1.233e-68	243.0	COG3795@1|root,COG3795@2|Bacteria,1Q42B@1224|Proteobacteria,439VS@68525|delta/epsilon subdivisions,2X59V@28221|Deltaproteobacteria,2Z0B4@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_5880450_0	1051006.HMPREF1162_1972	5.516e-224	713.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4DPBE@85009|Propionibacteriales	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
ZZS2_k127_5880450_1	518766.Rmar_0336	8.961e-110	391.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1FIT9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
ZZS2_k127_5890318_3	1120949.KB903356_gene8754	9.414e-07	63.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2I3FW@201174|Actinobacteria,4DMMS@85008|Micromonosporales	201174|Actinobacteria	EGMP	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
ZZS2_k127_5890318_1	1236959.BAMT01000001_gene1170	4.769e-40	169.0	COG0346@1|root,COG0346@2|Bacteria,1MZQY@1224|Proteobacteria,2VT5S@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS2_k127_5890318_2	1408433.JHXV01000008_gene89	3.083e-09	69.0	COG1357@1|root,COG3291@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria,4NMVW@976|Bacteroidetes,1I1JQ@117743|Flavobacteriia,2PBI2@246874|Cryomorphaceae	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
ZZS2_k127_5890318_4	1192034.CAP_5165	0.0002243	55.0	COG0402@1|root,COG1506@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,1R0DH@1224|Proteobacteria,43CWV@68525|delta/epsilon subdivisions,2X84T@28221|Deltaproteobacteria,2Z3KY@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PPC
ZZS2_k127_5890318_0	243090.RB12434	1.01e-117	403.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
ZZS2_k127_5951076_7	1210884.HG799466_gene12332	3.431e-05	51.0	COG1721@1|root,COG1721@2|Bacteria,2IZVM@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_5951076_4	204669.Acid345_2146	7.967e-18	98.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
ZZS2_k127_5951076_0	342113.DM82_5593	1.505e-68	243.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1K3TY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
ZZS2_k127_5951076_2	234267.Acid_4707	5.172e-56	209.0	COG0697@1|root,COG0697@2|Bacteria,3Y570@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_5951076_3	1122605.KB893637_gene3058	8.507e-30	124.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
ZZS2_k127_5951076_6	748658.KB907312_gene1096	2.394e-12	76.0	COG1669@1|root,COG1669@2|Bacteria,1NMHI@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
ZZS2_k127_5951076_5	555088.DealDRAFT_0358	1.572e-15	85.0	COG2445@1|root,COG2445@2|Bacteria,1VF87@1239|Firmicutes,24HS2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
ZZS2_k127_5951076_1	861299.J421_1183	1.244e-67	239.0	COG0429@1|root,COG0429@2|Bacteria,1ZSTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
ZZS2_k127_5953403_2	1150474.JQJI01000033_gene1634	1.219e-50	188.0	COG0264@1|root,COG0264@2|Bacteria,2GCGY@200918|Thermotogae	200918|Thermotogae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
ZZS2_k127_5953403_0	929703.KE386491_gene397	1.164e-79	273.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,47JC6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ZZS2_k127_5953403_5	243090.RB3886	5.132e-44	170.0	COG0233@1|root,COG0233@2|Bacteria,2IYYY@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
ZZS2_k127_5953403_7	59374.Fisuc_2743	2.526e-14	75.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
ZZS2_k127_5953403_6	96561.Dole_2627	3.679e-30	138.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
ZZS2_k127_5953403_4	751944.HALDL1_11050	1.538e-45	174.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y7KB@28890|Euryarchaeota,23UIG@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_5953403_3	1123070.KB899247_gene1469	3.625e-48	194.0	COG1657@1|root,COG1657@2|Bacteria,46U97@74201|Verrucomicrobia,2ITWF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_5953403_1	673860.AciM339_1521	1.807e-51	199.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,3F35H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS2_k127_5953403_8	1385518.N798_02105	6.701e-06	58.0	COG5542@1|root,COG5542@2|Bacteria,2HXZR@201174|Actinobacteria,4FIWN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
ZZS2_k127_5953403_9	1240349.ANGC01000007_gene1204	0.0004054	48.0	COG1051@1|root,COG1051@2|Bacteria,2I2P7@201174|Actinobacteria,4FW5K@85025|Nocardiaceae	201174|Actinobacteria	F	Glycosyltransferase family 87	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87,NUDIX
ZZS2_k127_5991851_2	243090.RB8028	4.72e-16	89.0	COG0515@1|root,COG0515@2|Bacteria,2J0PH@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_5991851_1	1366050.N234_14205	1.009e-31	130.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VXA4@28216|Betaproteobacteria,1KI81@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS2_k127_5991851_4	1394178.AWOO02000079_gene2140	6.001e-12	74.0	COG1734@1|root,COG1734@2|Bacteria,2IQMB@201174|Actinobacteria	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
ZZS2_k127_5991851_0	502025.Hoch_5425	1.754e-59	213.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2Z0YN@29|Myxococcales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
ZZS2_k127_5991851_5	1382303.JPOM01000001_gene1249	1.824e-06	53.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,2U76N@28211|Alphaproteobacteria,2KGJ2@204458|Caulobacterales	204458|Caulobacterales	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
ZZS2_k127_5991851_6	1123242.JH636434_gene4323	2.741e-05	48.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,2IWWY@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS2_k127_5992535_0	247490.KSU1_C1563	4.609e-150	494.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
ZZS2_k127_5992535_12	316274.Haur_4844	5.551e-05	56.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,3753X@32061|Chloroflexia	32061|Chloroflexia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
ZZS2_k127_5992535_1	247490.KSU1_B0551	7.047e-125	422.0	COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes	203682|Planctomycetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
ZZS2_k127_5992535_4	1142394.PSMK_07170	8.374e-63	245.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
ZZS2_k127_5992535_9	1089550.ATTH01000001_gene1301	1.2e-23	110.0	COG0494@1|root,COG0494@2|Bacteria,4PI8R@976|Bacteroidetes,1FJBC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
ZZS2_k127_5992535_7	1122238.AULR01000005_gene2140	2.801e-42	166.0	COG1611@1|root,COG1611@2|Bacteria,2GMM1@201174|Actinobacteria,4FP3K@85023|Microbacteriaceae	201174|Actinobacteria	F	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Lysine_decarbox,NUDIX
ZZS2_k127_5992535_5	521098.Aaci_2288	1.793e-49	190.0	COG0483@1|root,COG0483@2|Bacteria,1UKWB@1239|Firmicutes,4ITKN@91061|Bacilli	91061|Bacilli	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ZZS2_k127_5992535_10	272134.KB731324_gene5639	1.49e-10	71.0	COG3016@1|root,COG3016@2|Bacteria,1G1JQ@1117|Cyanobacteria,1H9S9@1150|Oscillatoriales	1117|Cyanobacteria	S	Iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
ZZS2_k127_5992535_3	243231.GSU0074	4.226e-70	244.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,42R54@68525|delta/epsilon subdivisions,2WMNZ@28221|Deltaproteobacteria,43U43@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM ThiJ PfpI domain protein	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
ZZS2_k127_5992535_6	504728.K649_11975	1.861e-48	188.0	COG1028@1|root,COG1028@2|Bacteria	504728.K649_11975|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5992535_2	1242864.D187_007363	1.184e-91	325.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5992535_8	502025.Hoch_0068	5.45e-38	166.0	COG3227@1|root,COG3227@2|Bacteria,1Q6DC@1224|Proteobacteria,432XR@68525|delta/epsilon subdivisions,2WYJ7@28221|Deltaproteobacteria,2Z34H@29|Myxococcales	28221|Deltaproteobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_5992535_11	521674.Plim_1876	5.115e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,2IZX2@203682|Planctomycetes	203682|Planctomycetes	K	sigma-70 factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6072097_1	717605.Theco_3483	5.999e-175	558.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,26REN@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
ZZS2_k127_6072097_5	391625.PPSIR1_30140	2.468e-71	268.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YXCH@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_6072097_3	671143.DAMO_0414	5.259e-94	328.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
ZZS2_k127_6072097_10	886293.Sinac_4694	9.149e-51	201.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_6072097_12	344747.PM8797T_14087	1.036e-30	132.0	COG0811@1|root,COG0811@2|Bacteria,2IYYI@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS2_k127_6072097_17	349124.Hhal_1247	0.0001866	50.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_6072097_16	1142394.PSMK_00320	2.902e-05	53.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_6072097_15	393595.ABO_1054	2.902e-05	53.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1XK2S@135619|Oceanospirillales	135619|Oceanospirillales	U	Biopolymer transport protein	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_6072097_19	936589.HMPREF1521_1776	0.0003502	49.0	COG0848@1|root,COG0848@2|Bacteria,1VAX1@1239|Firmicutes,4H5A0@909932|Negativicutes	909932|Negativicutes	U	Transport energizing protein, ExbD TolR family	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS2_k127_6072097_7	1254432.SCE1572_13235	8.278e-66	250.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
ZZS2_k127_6072097_4	204669.Acid345_0284	2.367e-91	336.0	COG1131@1|root,COG1131@2|Bacteria,3Y4CW@57723|Acidobacteria,2JMQR@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_6072097_0	589865.DaAHT2_2323	1.554e-180	592.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2WKEJ@28221|Deltaproteobacteria,2MI70@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
ZZS2_k127_6072097_8	56780.SYN_01800	6.313e-55	211.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_6072097_9	926569.ANT_31220	2.391e-52	199.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi	200795|Chloroflexi	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
ZZS2_k127_6072097_13	356851.JOAN01000025_gene4234	2.252e-19	104.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4D9VE@85008|Micromonosporales	201174|Actinobacteria	C	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
ZZS2_k127_6072097_11	562970.Btus_0866	1.358e-47	178.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
ZZS2_k127_6072097_6	1123242.JH636435_gene1367	1.775e-67	248.0	COG1502@1|root,COG1502@2|Bacteria,2IYFI@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
ZZS2_k127_6072097_14	756272.Plabr_4505	9.647e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,2IZ04@203682|Planctomycetes	203682|Planctomycetes	C	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_6072097_2	644282.Deba_0327	2.895e-120	403.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_6072097_18	562981.HMPREF0428_00529	0.0001985	52.0	COG1388@1|root,COG1388@2|Bacteria,1TXHT@1239|Firmicutes,4I6GX@91061|Bacilli,3WEWK@539002|Bacillales incertae sedis	91061|Bacilli	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
ZZS2_k127_6139086_1	269797.Mbar_A2782	1.638e-21	110.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02532@2157|Archaea,2Y7Q0@28890|Euryarchaeota	28890|Euryarchaeota	KLT	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_3
ZZS2_k127_6139086_0	521674.Plim_1915	2.381e-119	398.0	COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_6155300_8	1158756.AQXQ01000009_gene1130	2.771e-08	59.0	COG3119@1|root,COG3119@2|Bacteria,1PWEJ@1224|Proteobacteria,1RZ2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS2_k127_6155300_6	323261.Noc_1080	5.496e-17	89.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
ZZS2_k127_6155300_4	105559.Nwat_1947	2.007e-26	124.0	COG2020@1|root,COG2020@2|Bacteria,1RCWQ@1224|Proteobacteria	1224|Proteobacteria	O	protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
ZZS2_k127_6155300_3	1121904.ARBP01000001_gene5897	1.807e-51	199.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS2_k127_6155300_5	1123072.AUDH01000006_gene3243	1.937e-17	97.0	COG2230@1|root,COG2230@2|Bacteria,1R1FZ@1224|Proteobacteria,2TZ1A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS
ZZS2_k127_6155300_7	163908.KB235896_gene3907	4.835e-10	71.0	2A5JH@1|root,30U9U@2|Bacteria,1GK5Q@1117|Cyanobacteria,1HTB6@1161|Nostocales	1117|Cyanobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
ZZS2_k127_6155300_0	378806.STAUR_7200	1.354e-140	460.0	COG1032@1|root,COG1032@2|Bacteria,1RF63@1224|Proteobacteria,42S8Y@68525|delta/epsilon subdivisions,2WNX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
ZZS2_k127_6155300_9	246197.MXAN_6782	0.0001063	47.0	2AIWT@1|root,319EE@2|Bacteria,1Q2HH@1224|Proteobacteria,43E60@68525|delta/epsilon subdivisions,2WZUD@28221|Deltaproteobacteria,2Z2RZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
ZZS2_k127_6155300_1	861299.J421_3930	5.544e-79	275.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
ZZS2_k127_6155300_2	945713.IALB_1843	2.943e-60	219.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
ZZS2_k127_6197918_17	1206737.BAGF01000069_gene4260	1.875e-06	62.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4FXX7@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6197918_3	1120949.KB903357_gene4879	2.826e-57	227.0	COG0500@1|root,COG0500@2|Bacteria,2I2Y4@201174|Actinobacteria,4DMVF@85008|Micromonosporales	201174|Actinobacteria	Q	O-methyltransferase	-	-	2.1.1.303	ko:K20421	ko01059,ko01130,map01059,map01130	M00830	R10963	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2
ZZS2_k127_6197918_0	756272.Plabr_3149	7.739e-95	336.0	COG0644@1|root,COG0644@2|Bacteria,2J338@203682|Planctomycetes	2|Bacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,Trp_halogenase
ZZS2_k127_6197918_16	1206744.BAGL01000126_gene6190	1.319e-06	63.0	COG3055@1|root,COG3055@2|Bacteria,2GK14@201174|Actinobacteria,4FUXU@85025|Nocardiaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,FG-GAP,VCBS
ZZS2_k127_6197918_9	1352941.M877_13960	4.276e-12	71.0	COG0726@1|root,COG3055@1|root,COG0726@2|Bacteria,COG3055@2|Bacteria,2GK14@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,PA14
ZZS2_k127_6197918_11	153948.NAL212_2848	2.348e-09	72.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	3.1.4.50	ko:K01127	ko00563,map00563	-	R06623	-	ko00000,ko00001,ko01000	-	-	-	Big_5,Calx-beta,FG-GAP,HemolysinCabind
ZZS2_k127_6197918_5	1206744.BAGL01000126_gene6190	1.024e-30	140.0	COG3055@1|root,COG3055@2|Bacteria,2GK14@201174|Actinobacteria,4FUXU@85025|Nocardiaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,FG-GAP,VCBS
ZZS2_k127_6197918_7	1076550.LH22_15085	1.457e-23	102.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,3W0XD@53335|Pantoea	1236|Gammaproteobacteria	IQ	Acyl Carrier Protein	RS00794	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS2_k127_6197918_6	644801.Psest_3691	1.943e-29	124.0	COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,1S9TC@1236|Gammaproteobacteria,1Z2SN@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	IspA
ZZS2_k127_6197918_14	1453503.AU05_08595	2.29e-07	63.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria,1YEP2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
ZZS2_k127_6197918_4	546262.NEICINOT_04763	1.613e-44	184.0	COG1215@1|root,COG1215@2|Bacteria,1QUUY@1224|Proteobacteria,2WHTK@28216|Betaproteobacteria,2KQQZ@206351|Neisseriales	206351|Neisseriales	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6197918_2	391625.PPSIR1_04498	5.806e-74	271.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,42PI2@68525|delta/epsilon subdivisions,2WMFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
ZZS2_k127_6197918_8	1384056.N787_02085	7.673e-15	87.0	COG0824@1|root,COG0824@2|Bacteria,1RH6W@1224|Proteobacteria,1S6BU@1236|Gammaproteobacteria,1X6UW@135614|Xanthomonadales	135614|Xanthomonadales	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
ZZS2_k127_6197918_15	1254432.SCE1572_22560	1.237e-06	61.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
ZZS2_k127_6197918_18	351016.RAZWK3B_05557	1.164e-05	58.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,2P1FG@2433|Roseobacter	28211|Alphaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ZZS2_k127_6197918_19	1136417.AZWE01000078_gene257	7.752e-05	54.0	COG2849@1|root,COG2849@2|Bacteria,2GV9D@201174|Actinobacteria	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
ZZS2_k127_6197918_10	573370.DMR_02790	1.798e-11	76.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_6197918_13	595460.RRSWK_06192	7.085e-08	64.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.98.6,1.11.1.15,1.8.1.9,1.8.4.11,1.8.4.12	ko:K00384,ko:K03564,ko:K12057,ko:K12267,ko:K21636	ko00230,ko00240,ko00450,ko01100,map00230,map00240,map00450,map01100	M00053	R02016,R03596,R09372,R11633,R11634,R11635,R11636	RC00013,RC00613,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.7.11.1	-	-	AhpC-TSA
ZZS2_k127_6197918_12	1136163.M565_ctg1P1782	6.051e-09	66.0	COG2834@1|root,COG2834@2|Bacteria,1R5HR@1224|Proteobacteria,1RSIT@1236|Gammaproteobacteria,1XV2C@135623|Vibrionales	135623|Vibrionales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
ZZS2_k127_6197918_1	391625.PPSIR1_04523	2.793e-88	318.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,42P70@68525|delta/epsilon subdivisions,2WJGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
ZZS2_k127_622707_1	290397.Adeh_1423	1.599e-117	379.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria,2YWQF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
ZZS2_k127_622707_0	404589.Anae109_2406	3.41e-172	553.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
ZZS2_k127_622707_2	1232410.KI421424_gene1761	1.745e-28	131.0	2EXQK@1|root,33R03@2|Bacteria,1NQU4@1224|Proteobacteria,42Y7S@68525|delta/epsilon subdivisions,2WTT3@28221|Deltaproteobacteria,43UGY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6238094_1	1303518.CCALI_00439	9.408e-116	383.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	MA20_31690	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_6238094_4	1196835.A458_07015	3.415e-11	66.0	2CA5H@1|root,33A7N@2|Bacteria,1NI9X@1224|Proteobacteria,1T9T1@1236|Gammaproteobacteria,1Z3IT@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
ZZS2_k127_6238094_0	1356854.N007_10155	2.458e-120	424.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
ZZS2_k127_6238094_6	457570.Nther_0049	0.0001721	53.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6238094_5	926692.AZYG01000059_gene153	1.12e-06	60.0	COG1366@1|root,COG1366@2|Bacteria,1TU2C@1239|Firmicutes,25NUF@186801|Clostridia,3WC0I@53433|Halanaerobiales	186801|Clostridia	T	STAS domain	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
ZZS2_k127_6238094_2	316274.Haur_4061	1.542e-42	177.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
ZZS2_k127_6238094_3	755178.Cyan10605_0856	1.542e-24	107.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS2_k127_6257283_1	1449126.JQKL01000005_gene875	1.607e-69	242.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,268HM@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS2_k127_6257283_2	517418.Ctha_0874	2.358e-53	199.0	COG0224@1|root,COG0224@2|Bacteria,1FD78@1090|Chlorobi	1090|Chlorobi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
ZZS2_k127_6257283_0	1340493.JNIF01000004_gene349	1.811e-185	606.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
ZZS2_k127_6257283_4	717605.Theco_3862	2.4e-14	85.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,26UM4@186822|Paenibacillaceae	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
ZZS2_k127_6257283_5	290512.Paes_2245	4.764e-14	80.0	COG0711@1|root,COG0711@2|Bacteria,1FDW3@1090|Chlorobi	1090|Chlorobi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
ZZS2_k127_6257283_6	1121481.AUAS01000007_gene985	1.043e-13	74.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,47S5V@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
ZZS2_k127_6257283_3	1191523.MROS_0276	6.567e-38	154.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
ZZS2_k127_6258289_5	1173023.KE650771_gene2359	1.311e-10	63.0	COG1232@1|root,COG2246@1|root,COG1232@2|Bacteria,COG2246@2|Bacteria,1G05M@1117|Cyanobacteria,1JK4H@1189|Stigonemataceae	1117|Cyanobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,GtrA
ZZS2_k127_6258289_3	1097668.BYI23_A010360	7.6e-23	108.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,1K3RS@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
ZZS2_k127_6258289_2	1123508.JH636439_gene1515	3.413e-48	184.0	COG0611@1|root,COG0611@2|Bacteria,2IZG9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS2_k127_6258289_6	1114964.L485_00055	5.212e-10	70.0	COG1637@1|root,COG1637@2|Bacteria,1NA4I@1224|Proteobacteria	1224|Proteobacteria	L	Pfam:DUF91	-	-	-	ko:K07448,ko:K07503	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	NucS
ZZS2_k127_6258289_0	502025.Hoch_6834	3.465e-116	398.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2YV6I@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
ZZS2_k127_6258289_1	55529.EKX40456	6.679e-56	204.0	COG0800@1|root,2QVAJ@2759|Eukaryota	2759|Eukaryota	G	KDPG and KHG aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase,RraA-like
ZZS2_k127_6276219_1	760568.Desku_2810	2.479e-92	331.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,261GJ@186807|Peptococcaceae	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_6276219_8	197221.22294995	0.0001627	53.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
ZZS2_k127_6276219_2	986075.CathTA2_0866	7.49e-81	290.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_6276219_3	292459.STH1727	9.684e-64	234.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
ZZS2_k127_6276219_6	448385.sce8168	2.034e-25	117.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2YUQX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
ZZS2_k127_6276219_0	247490.KSU1_B0370	1.91e-298	937.0	COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
ZZS2_k127_6276219_5	123214.PERMA_0136	6.002e-26	113.0	COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae	200783|Aquificae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
ZZS2_k127_6276219_4	861299.J421_4476	2.45e-50	184.0	COG2318@1|root,COG2318@2|Bacteria,1ZU06@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS2_k127_6276219_7	197221.22294095	9.979e-06	57.0	COG1232@1|root,COG1232@2|Bacteria,1G38A@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
ZZS2_k127_6277148_0	867903.ThesuDRAFT_00352	2.938e-99	340.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
ZZS2_k127_6277148_1	1286106.MPL1_00897	3.335e-54	214.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,462Q4@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_6277148_3	1105367.CG50_04950	9.251e-20	103.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2UCCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lipid A Biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
ZZS2_k127_6277148_6	883126.HMPREF9710_00827	2.798e-13	83.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,477ST@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
ZZS2_k127_6277148_5	247490.KSU1_C0795	5.596e-14	84.0	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS2_k127_6277148_2	391625.PPSIR1_04683	1.8e-45	171.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
ZZS2_k127_6277148_4	290397.Adeh_3316	2.548e-18	98.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
ZZS2_k127_628766_8	886293.Sinac_2473	2.217e-28	119.0	COG5653@1|root,COG5653@2|Bacteria,2J18H@203682|Planctomycetes	203682|Planctomycetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
ZZS2_k127_628766_9	479434.Sthe_1809	1.151e-20	109.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi,27YGX@189775|Thermomicrobia	189775|Thermomicrobia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
ZZS2_k127_628766_1	498761.HM1_2048	9.864e-86	295.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia	186801|Clostridia	H	PFAM UBA THIF-type NAD FAD binding	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
ZZS2_k127_628766_3	997346.HMPREF9374_2499	1.027e-69	250.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HDS3@91061|Bacilli,27B70@186824|Thermoactinomycetaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS2_k127_628766_4	886293.Sinac_3586	4.148e-49	202.0	COG0515@1|root,COG1335@1|root,COG0515@2|Bacteria,COG1335@2|Bacteria,2IZ3W@203682|Planctomycetes	203682|Planctomycetes	Q	Isochorismatase family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Isochorismatase
ZZS2_k127_628766_11	246197.MXAN_4739	1.141e-15	93.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
ZZS2_k127_628766_12	1444770.AF72_02175	5.109e-08	67.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1X43X@135614|Xanthomonadales	135614|Xanthomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
ZZS2_k127_628766_6	1396141.BATP01000003_gene4982	2.174e-39	159.0	COG0564@1|root,COG1054@1|root,COG0564@2|Bacteria,COG1054@2|Bacteria,46VK6@74201|Verrucomicrobia,2IUAG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2,Rhodanese
ZZS2_k127_628766_2	234267.Acid_2124	1.448e-81	288.0	COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS2_k127_628766_10	1454010.JEOE01000043_gene2570	3.167e-18	90.0	COG2314@1|root,COG2314@2|Bacteria,2GU27@201174|Actinobacteria	201174|Actinobacteria	M	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,TM2
ZZS2_k127_628766_5	452637.Oter_2393	4.3e-44	169.0	COG1051@1|root,COG1051@2|Bacteria,46VWV@74201|Verrucomicrobia	74201|Verrucomicrobia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS2_k127_628766_0	757424.Hsero_2729	4.193e-96	334.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VJQV@28216|Betaproteobacteria,475KN@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
ZZS2_k127_628766_7	330214.NIDE1418	1.08e-33	141.0	COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
ZZS2_k127_6299661_9	7668.SPU_015508-tr	4.894e-06	60.0	2BW0M@1|root,2QTDG@2759|Eukaryota,38G52@33154|Opisthokonta,3BGNE@33208|Metazoa,3CVZ1@33213|Bilateria	33208|Metazoa	S	Von Willebrand factor A	VWA3A	-	-	-	-	-	-	-	-	-	-	-	VWA_3
ZZS2_k127_6299661_3	1121920.AUAU01000007_gene488	1.526e-107	356.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
ZZS2_k127_6299661_5	1121920.AUAU01000007_gene489	5.502e-78	284.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS2_k127_6299661_6	1121920.AUAU01000007_gene490	6.087e-64	244.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
ZZS2_k127_6299661_1	1121920.AUAU01000007_gene491	1.99e-122	419.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
ZZS2_k127_6299661_2	1121920.AUAU01000007_gene493	4.531e-119	395.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
ZZS2_k127_6299661_8	555779.Dthio_PD2126	2.532e-52	189.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
ZZS2_k127_6299661_4	1254432.SCE1572_42705	5.141e-97	332.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2YYNR@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_6299661_7	1000565.METUNv1_02187	8.614e-55	198.0	2DNYA@1|root,32ZS5@2|Bacteria,1Q6RG@1224|Proteobacteria,2VYR9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF1877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1877
ZZS2_k127_6299661_10	323848.Nmul_A1375	0.0002684	55.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria,3738I@32003|Nitrosomonadales	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
ZZS2_k127_6299661_0	1229780.BN381_130026	0.0	1073.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,3UWEV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
ZZS2_k127_650256_0	1507.HMPREF0262_01919	6.108e-270	860.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS2_k127_650256_1	761193.Runsl_3873	1.134e-73	258.0	COG1131@1|root,COG1131@2|Bacteria,4NJ0D@976|Bacteroidetes,47K40@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_650256_2	1166018.FAES_0541	2.745e-21	110.0	28HMX@1|root,2Z7WB@2|Bacteria,4NFY2@976|Bacteroidetes,47MX8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_65290_6	1133850.SHJG_3808	0.0004377	51.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_65290_4	1121403.AUCV01000010_gene1331	7.618e-115	384.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2MIGE@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
ZZS2_k127_65290_5	207559.Dde_2729	1.301e-54	219.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,42PDB@68525|delta/epsilon subdivisions,2WJBQ@28221|Deltaproteobacteria,2MH9H@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
ZZS2_k127_65290_3	518766.Rmar_1420	4.607e-123	417.0	COG1228@1|root,COG1228@2|Bacteria,4P0AG@976|Bacteroidetes,1FJ21@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS2_k127_65290_0	518766.Rmar_1421	9.145e-153	505.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ZZS2_k127_65290_2	1267535.KB906767_gene5052	1.154e-126	432.0	COG3591@1|root,COG3591@2|Bacteria,3Y2TU@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
ZZS2_k127_65290_1	861299.J421_0094	6.591e-127	417.0	COG0520@1|root,COG0520@2|Bacteria,1ZT1P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS2_k127_6581683_1	1444309.JAQG01000105_gene345	5.328e-91	305.0	COG1061@1|root,COG1061@2|Bacteria,1TPDM@1239|Firmicutes,4HB32@91061|Bacilli,26UKS@186822|Paenibacillaceae	91061|Bacilli	L	helicase	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
ZZS2_k127_6581683_2	1480694.DC28_04165	7.621e-05	56.0	2F2R9@1|root,33VMJ@2|Bacteria,2J5DF@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
ZZS2_k127_6581683_0	313612.L8106_23665	2.116e-92	321.0	COG1232@1|root,COG2246@1|root,COG1232@2|Bacteria,COG2246@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,GtrA
ZZS2_k127_6606068_33	388467.A19Y_3285	1.08e-06	58.0	COG2755@1|root,COG2755@2|Bacteria,1G3BA@1117|Cyanobacteria,1H9ZK@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
ZZS2_k127_6606068_0	344747.PM8797T_18941	3.806e-246	775.0	COG2192@1|root,COG2192@2|Bacteria,2IYCS@203682|Planctomycetes	203682|Planctomycetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
ZZS2_k127_6606068_37	522306.CAP2UW1_3566	9.374e-05	51.0	2E3ZS@1|root,32YWP@2|Bacteria,1NAZV@1224|Proteobacteria,2W4P7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6606068_29	595460.RRSWK_05226	3.981e-10	65.0	2EGPU@1|root,32K36@2|Bacteria,2J1G1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6606068_4	595460.RRSWK_01212	9.626e-75	261.0	COG0568@1|root,COG0568@2|Bacteria,2IYCB@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_6606068_5	264732.Moth_0582	3.43e-74	263.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ZZS2_k127_6606068_15	344747.PM8797T_29678	2.293e-53	196.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
ZZS2_k127_6606068_32	69279.BG36_16875	4.079e-07	62.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U6WT@28211|Alphaproteobacteria,43I59@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB1	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS2_k127_6606068_7	1157490.EL26_22010	1.596e-64	231.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,27886@186823|Alicyclobacillaceae	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
ZZS2_k127_6606068_17	1134413.ANNK01000001_gene2132	7.635e-39	154.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus	91061|Bacilli	D	COG1192 ATPases involved in chromosome partitioning	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
ZZS2_k127_6606068_14	1396141.BATP01000027_gene1148	5.583e-56	205.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia,2ITKJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
ZZS2_k127_6606068_11	420324.KI912045_gene4100	8.722e-59	231.0	COG2120@1|root,COG2120@2|Bacteria,1NN0N@1224|Proteobacteria,2TUJ2@28211|Alphaproteobacteria,1JXCP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS2_k127_6606068_30	1192034.CAP_2839	7.929e-10	70.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria,2YVW2@29|Myxococcales	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
ZZS2_k127_6606068_1	234267.Acid_2834	5.403e-119	397.0	COG1236@1|root,COG1236@2|Bacteria,3Y6U0@57723|Acidobacteria	57723|Acidobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
ZZS2_k127_6606068_9	1378168.N510_00112	2.819e-61	227.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes	1239|Firmicutes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
ZZS2_k127_6606068_8	255470.cbdbA1675	2.12e-62	222.0	COG1704@1|root,COG1704@2|Bacteria,2GAPS@200795|Chloroflexi,34D06@301297|Dehalococcoidia	301297|Dehalococcoidia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS2_k127_6606068_35	1210884.HG799472_gene14762	2.264e-05	57.0	COG0501@1|root,COG0501@2|Bacteria,2J0VM@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
ZZS2_k127_6606068_27	345219.Bcoa_2940	2.027e-15	90.0	COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,4HCGD@91061|Bacilli,1ZBUQ@1386|Bacillus	91061|Bacilli	S	Involved in the degradation of specific anti-sigma factors	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
ZZS2_k127_6606068_18	530564.Psta_2697	4.485e-33	148.0	COG1413@1|root,COG1520@1|root,COG1413@2|Bacteria,COG1520@2|Bacteria,2J3VN@203682|Planctomycetes	2|Bacteria	C	HEAT repeats	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	DNA_alkylation,HEAT_2,MFS_1,PQQ_2,cNMP_binding
ZZS2_k127_6606068_36	1123508.JH636440_gene2792	4.416e-05	58.0	COG1520@1|root,COG1520@2|Bacteria,2IZ2Z@203682|Planctomycetes	203682|Planctomycetes	H	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,TPR_6
ZZS2_k127_6606068_3	886293.Sinac_3984	3.455e-79	300.0	COG2373@1|root,COG2373@2|Bacteria,2IYJD@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_6606068_10	530564.Psta_2699	4.447e-61	236.0	COG1874@1|root,COG2304@1|root,COG1874@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
ZZS2_k127_6606068_2	530564.Psta_2696	9.029e-86	314.0	COG2304@1|root,COG2304@2|Bacteria,2IYCE@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
ZZS2_k127_6606068_20	530564.Psta_3226	3.323e-30	139.0	COG1196@1|root,COG1196@2|Bacteria,2IXVI@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6606068_21	530564.Psta_2720	3.06e-23	115.0	COG3767@1|root,COG3767@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	EF-hand_5
ZZS2_k127_6606068_31	1123242.JH636435_gene1210	1.496e-08	67.0	29G09@1|root,338KE@2|Bacteria,2J16F@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6606068_22	1210884.HG799465_gene11426	6.207e-22	111.0	COG0810@1|root,COG0810@2|Bacteria,2J05E@203682|Planctomycetes	203682|Planctomycetes	M	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
ZZS2_k127_6606068_6	521674.Plim_1809	8.748e-66	248.0	COG0265@1|root,COG0265@2|Bacteria,2IXA0@203682|Planctomycetes	203682|Planctomycetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_6606068_19	530564.Psta_2724	3.734e-32	142.0	COG0265@1|root,COG0265@2|Bacteria,2IYHB@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_6606068_13	521674.Plim_1811	3.868e-57	223.0	COG0265@1|root,COG0265@2|Bacteria,2IY6F@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_6606068_26	338966.Ppro_1213	2.285e-16	90.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016,ko:K16092	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	1.B.14.3,3.A.1.14	-	-	Peripla_BP_2
ZZS2_k127_6606068_12	446471.Xcel_2760	2.463e-58	225.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4F48R@85017|Promicromonosporaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
ZZS2_k127_6606068_16	268739.Nmlp_3091	3.649e-51	201.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,23SRW@183963|Halobacteria	183963|Halobacteria	E	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	btuD	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
ZZS2_k127_6606068_24	313596.RB2501_08130	2.445e-20	95.0	2ARAZ@1|root,31GKZ@2|Bacteria,4NKJD@976|Bacteroidetes,1I0HH@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF3332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3332
ZZS2_k127_6606068_23	1144275.COCOR_05233	1.995e-20	102.0	COG2849@1|root,COG2849@2|Bacteria,1NMUU@1224|Proteobacteria,432BU@68525|delta/epsilon subdivisions,2WT7D@28221|Deltaproteobacteria,2Z2M9@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
ZZS2_k127_6606068_25	502025.Hoch_2192	1.718e-17	91.0	COG0824@1|root,COG0824@2|Bacteria,1Q2J2@1224|Proteobacteria,433TX@68525|delta/epsilon subdivisions,2X3FR@28221|Deltaproteobacteria,2YVWT@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT
ZZS2_k127_6606068_28	1123058.KB894240_gene2052	1.52e-14	75.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
ZZS2_k127_6607232_4	1304275.C41B8_00915	6.988e-14	75.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST,RimK
ZZS2_k127_6607232_3	56110.Oscil6304_5767	3.95e-14	85.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria,1HAKG@1150|Oscillatoriales	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6607232_1	1242864.D187_000533	7.222e-31	136.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,431AM@68525|delta/epsilon subdivisions,2WWZH@28221|Deltaproteobacteria,2Z2VQ@29|Myxococcales	28221|Deltaproteobacteria	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
ZZS2_k127_6607232_0	661478.OP10G_3682	4.645e-49	184.0	COG5553@1|root,COG5553@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
ZZS2_k127_6607232_2	278963.ATWD01000001_gene3669	6.961e-22	96.0	COG0745@1|root,COG0745@2|Bacteria,3Y4GX@57723|Acidobacteria,2JJ6P@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_6609604_15	1464048.JNZS01000019_gene2327	2.444e-39	151.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4D8J2@85008|Micromonosporales	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
ZZS2_k127_6609604_4	575540.Isop_2690	6.483e-129	434.0	COG4242@1|root,COG4242@2|Bacteria,2IWZJ@203682|Planctomycetes	203682|Planctomycetes	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
ZZS2_k127_6609604_14	935845.JADQ01000092_gene4072	2.78e-40	156.0	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,26YKY@186822|Paenibacillaceae	91061|Bacilli	S	Thiol-disulfide oxidoreductase DCC	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
ZZS2_k127_6609604_19	243231.GSU0926	2.295e-21	107.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43TRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS2_k127_6609604_9	518766.Rmar_0706	7.302e-62	237.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1FIW0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS2_k127_6609604_16	1385935.N836_01855	1.532e-37	157.0	COG0767@1|root,COG0767@2|Bacteria,1FZVP@1117|Cyanobacteria,1H7CQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Belongs to the MlaE permease family	ycf63	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS2_k127_6609604_18	795359.TOPB45_1208	2.778e-23	117.0	COG3170@1|root,COG3170@2|Bacteria,2GGY6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6609604_5	237368.SCABRO_01228	9.747e-106	352.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1b
ZZS2_k127_6609604_25	331869.BAL199_05599	6.605e-07	62.0	COG0457@1|root,COG0457@2|Bacteria	331869.BAL199_05599|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6609604_29	1129374.AJE_07151	0.0001124	53.0	COG0478@1|root,COG1519@1|root,COG0478@2|Bacteria,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,464WA@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
ZZS2_k127_6609604_20	1142394.PSMK_24200	4.182e-21	102.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ZZS2_k127_6609604_3	1089547.KB913013_gene2799	2.738e-151	487.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
ZZS2_k127_6609604_6	370438.PTH_1939	7.922e-104	364.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
ZZS2_k127_6609604_24	998674.ATTE01000001_gene2209	4.322e-07	59.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales	1224|Proteobacteria	T	response regulator receiver	dctD	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_6609604_27	87626.PTD2_18440	3.815e-06	50.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,2Q3RJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6609604_26	1410668.JNKC01000016_gene993	1.171e-06	51.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6609604_2	243090.RB7894	1.59e-185	590.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
ZZS2_k127_6609604_28	344747.PM8797T_12121	6.894e-06	55.0	COG0690@1|root,COG0690@2|Bacteria,2J0E7@203682|Planctomycetes	203682|Planctomycetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
ZZS2_k127_6609604_13	247490.KSU1_C1196	1.219e-49	184.0	COG0250@1|root,COG0250@2|Bacteria,2IZ9N@203682|Planctomycetes	203682|Planctomycetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
ZZS2_k127_6609604_12	498761.HM1_1365	3.205e-52	187.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
ZZS2_k127_6609604_7	247490.KSU1_C1198	9.015e-77	263.0	COG0081@1|root,COG0081@2|Bacteria,2IYQK@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
ZZS2_k127_6609604_22	411470.RUMGNA_01563	1.351e-16	87.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3XZVD@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
ZZS2_k127_6609604_17	264732.Moth_2469	2.261e-37	145.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,42GKP@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
ZZS2_k127_6609604_1	530564.Psta_2551	0.0	1544.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
ZZS2_k127_6609604_0	886293.Sinac_0499	0.0	1912.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
ZZS2_k127_6609604_10	857293.CAAU_2111	3.665e-59	207.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,36IR5@31979|Clostridiaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
ZZS2_k127_6609604_11	886293.Sinac_0492	1.567e-53	192.0	COG0049@1|root,COG0049@2|Bacteria,2IZ7I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
ZZS2_k127_6609604_21	518766.Rmar_0383	1.811e-18	95.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1FJDU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
ZZS2_k127_6609604_23	1415780.JPOG01000001_gene2987	1.002e-15	91.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1X3DW@135614|Xanthomonadales	135614|Xanthomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
ZZS2_k127_6609604_8	1216932.CM240_2170	2.598e-76	272.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,36DT0@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
ZZS2_k127_6626262_0	1123242.JH636435_gene2121	6.712e-271	872.0	28KJF@1|root,2Z84W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6626262_6	575540.Isop_3572	4.706e-48	181.0	2ECWJ@1|root,336TU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6626262_4	575540.Isop_3571	9.473e-96	325.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
ZZS2_k127_6626262_3	575540.Isop_3570	9.261e-97	332.0	COG2304@1|root,COG2304@2|Bacteria,2IXVS@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
ZZS2_k127_6626262_7	1396141.BATP01000040_gene2150	3.354e-29	132.0	2BXEQ@1|root,33IN8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6626262_5	575540.Isop_3568	1.792e-89	316.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_6626262_2	3880.AES83106	1.989e-147	474.0	2D0PP@1|root,2SEXG@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
ZZS2_k127_6626262_1	575540.Isop_3573	6.86e-163	533.0	2DUKG@1|root,33R4D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6678185_5	398720.MED217_14650	4.091e-15	84.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1I2WA@117743|Flavobacteriia,2XJHT@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
ZZS2_k127_6678185_4	1008457.BAEX01000086_gene3022	1.358e-22	106.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1I2WA@117743|Flavobacteriia,47IEA@76831|Myroides	976|Bacteroidetes	M	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
ZZS2_k127_6678185_2	1348114.OM33_21000	1.085e-80	287.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,2Q3UZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS2_k127_6678185_3	390989.JOEG01000009_gene1110	1.441e-24	118.0	COG0815@1|root,COG0815@2|Bacteria,2GP8X@201174|Actinobacteria,4DGGT@85008|Micromonosporales	201174|Actinobacteria	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
ZZS2_k127_6678185_0	864069.MicloDRAFT_00060910	4.762e-274	850.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,1JWUA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
ZZS2_k127_6678185_1	1123508.JH636441_gene3216	2.112e-136	451.0	28MB6@1|root,2ZAPQ@2|Bacteria,2IWSP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6686055_6	404589.Anae109_3779	4.847e-46	174.0	COG1762@1|root,COG1762@2|Bacteria,1RG0Z@1224|Proteobacteria,42RSF@68525|delta/epsilon subdivisions,2WNXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
ZZS2_k127_6686055_10	452637.Oter_1763	2.832e-23	115.0	2F18Q@1|root,33U9U@2|Bacteria,46V23@74201|Verrucomicrobia,3K9F0@414999|Opitutae	414999|Opitutae	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS2_k127_6686055_1	243090.RB1248	1.284e-91	309.0	COG1131@1|root,COG1131@2|Bacteria,2IXQV@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_6686055_0	886293.Sinac_4981	8.653e-163	552.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
ZZS2_k127_6686055_2	886293.Sinac_4980	5.339e-80	304.0	COG3266@1|root,COG3266@2|Bacteria,2IZFW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
ZZS2_k127_6686055_12	1123242.JH636435_gene1455	2.887e-10	70.0	COG0265@1|root,COG0526@1|root,COG0265@2|Bacteria,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_6686055_11	886293.Sinac_7486	6.318e-19	90.0	COG0526@1|root,COG4099@1|root,COG0526@2|Bacteria,COG4099@2|Bacteria,2IZGJ@203682|Planctomycetes	203682|Planctomycetes	M	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,PMT_2,Peptidase_S9
ZZS2_k127_6686055_3	1121430.JMLG01000001_gene2144	1.59e-63	232.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,260VP@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
ZZS2_k127_6686055_8	4006.Lus10022255	7.748e-39	153.0	COG0242@1|root,KOG3137@2759|Eukaryota,37IBM@33090|Viridiplantae,3G9JA@35493|Streptophyta,4JDMQ@91835|fabids	35493|Streptophyta	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	PDF1B	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ZZS2_k127_6686055_9	583355.Caka_2956	3.005e-24	117.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,46V40@74201|Verrucomicrobia,3K7D2@414999|Opitutae	414999|Opitutae	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6686055_13	484019.THA_109	1.675e-05	50.0	COG0268@1|root,COG0268@2|Bacteria,2GDFA@200918|Thermotogae	200918|Thermotogae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
ZZS2_k127_6686055_5	886293.Sinac_4694	8.78e-50	198.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_6686055_4	1192034.CAP_3530	6.739e-57	219.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
ZZS2_k127_6686055_7	1303518.CCALI_01587	1.4e-42	161.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
ZZS2_k127_6764472_5	886293.Sinac_4405	1.028e-40	158.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
ZZS2_k127_6764472_4	886293.Sinac_4407	1.379e-57	215.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS2_k127_6764472_3	886293.Sinac_4404	3.162e-73	271.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS2_k127_6764472_9	1122247.C731_1921	0.0007134	51.0	COG3178@1|root,COG3178@2|Bacteria,2GN8T@201174|Actinobacteria,23F8B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
ZZS2_k127_6764472_8	1385519.N801_14285	0.0003092	53.0	2DNX5@1|root,32ZMQ@2|Bacteria,2GR11@201174|Actinobacteria,4FIV8@85021|Intrasporangiaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS2_k127_6764472_6	886293.Sinac_4403	2.324e-17	95.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
ZZS2_k127_6764472_1	251229.Chro_0877	2.221e-157	533.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,3VINJ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS2_k127_6764472_0	335543.Sfum_3546	9.131e-270	857.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MS0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
ZZS2_k127_6764472_2	1267533.KB906740_gene292	1.157e-145	479.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
ZZS2_k127_6775996_27	279238.Saro_2003	4.922e-11	62.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,2K0R8@204457|Sphingomonadales	204457|Sphingomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
ZZS2_k127_6775996_22	562970.Btus_1456	5.172e-29	124.0	COG0681@1|root,COG0681@2|Bacteria,1TRAV@1239|Firmicutes,4HCTU@91061|Bacilli,27APW@186823|Alicyclobacillaceae	91061|Bacilli	U	Belongs to the peptidase S26 family	sipS3	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
ZZS2_k127_6775996_10	886293.Sinac_1313	2.235e-98	339.0	COG1508@1|root,COG1508@2|Bacteria,2IXGU@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
ZZS2_k127_6775996_23	1123253.AUBD01000006_gene818	3.599e-23	108.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1X4CK@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6775996_33	1122603.ATVI01000009_gene2513	3.309e-05	55.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1X3ZU@135614|Xanthomonadales	135614|Xanthomonadales	U	General secretion pathway protein	xcsF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
ZZS2_k127_6775996_9	330214.NIDE3575	1.113e-104	352.0	COG0717@1|root,COG0717@2|Bacteria,3J0WG@40117|Nitrospirae	40117|Nitrospirae	F	2'-deoxycytidine 5'-triphosphate deaminase (DCD)	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
ZZS2_k127_6775996_0	518766.Rmar_1705	1.823e-307	963.0	COG1960@1|root,COG1960@2|Bacteria,4P1V8@976|Bacteroidetes,1FIUE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Domain of unknown function (DUF1974)	-	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
ZZS2_k127_6775996_19	1163408.UU9_11475	4.411e-44	168.0	COG0454@1|root,COG0456@2|Bacteria,1RAJC@1224|Proteobacteria,1S1YW@1236|Gammaproteobacteria,1X6QN@135614|Xanthomonadales	135614|Xanthomonadales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
ZZS2_k127_6775996_13	452637.Oter_0962	1.56e-71	260.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.2.1.52,3.5.1.28	ko:K01207,ko:K01447	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R04112,R05963,R07809,R07810,R10831	RC00049,RC00064,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidase_2,PG_binding_1
ZZS2_k127_6775996_4	1519464.HY22_10360	4.011e-139	461.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS2_k127_6775996_15	575540.Isop_1883	3.67e-55	216.0	COG2234@1|root,COG2234@2|Bacteria,2J3AQ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_6775996_21	1121920.AUAU01000009_gene1944	6.837e-37	143.0	COG1832@1|root,COG1832@2|Bacteria,3Y5TA@57723|Acidobacteria	57723|Acidobacteria	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
ZZS2_k127_6775996_12	1415780.JPOG01000001_gene1476	6.993e-84	286.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,1S0RN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS2_k127_6775996_1	1123248.KB893317_gene4397	5.615e-175	557.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1ISPB@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_6775996_25	448385.sce8680	1.095e-17	92.0	COG1595@1|root,COG1595@2|Bacteria,1RKMN@1224|Proteobacteria,431Z5@68525|delta/epsilon subdivisions,2WWH8@28221|Deltaproteobacteria,2Z13Y@29|Myxococcales	28221|Deltaproteobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_6775996_32	1385513.N780_06515	1.718e-05	57.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,2Y9IZ@289201|Pontibacillus	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS2_k127_6775996_31	1192034.CAP_1661	1.566e-06	61.0	COG0784@1|root,COG0784@2|Bacteria,1QAM7@1224|Proteobacteria,43563@68525|delta/epsilon subdivisions,2WZH3@28221|Deltaproteobacteria,2Z24X@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
ZZS2_k127_6775996_7	589865.DaAHT2_2643	3.881e-120	407.0	COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,43AKI@68525|delta/epsilon subdivisions,2WQEI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ZZS2_k127_6775996_11	305700.B447_05690	3.517e-96	322.0	COG3638@1|root,COG3638@2|Bacteria,1MXYA@1224|Proteobacteria,2VM4F@28216|Betaproteobacteria,2KZ2G@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
ZZS2_k127_6775996_17	232721.Ajs_1691	1.162e-47	184.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,4AAF8@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
ZZS2_k127_6775996_18	383372.Rcas_4314	2.371e-46	183.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_6775996_26	522306.CAP2UW1_1842	9.319e-15	87.0	COG0500@1|root,COG2226@2|Bacteria,1Q73B@1224|Proteobacteria,2W6KU@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS2_k127_6775996_24	102129.Lepto7375DRAFT_0132	2.273e-18	95.0	COG4113@1|root,COG4113@2|Bacteria,1G8IF@1117|Cyanobacteria,1HBD3@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
ZZS2_k127_6775996_28	102232.GLO73106DRAFT_00034650	8.35e-09	61.0	arCOG09589@1|root,33BW0@2|Bacteria,1GA6A@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6775996_6	1480694.DC28_11295	3.199e-126	417.0	COG1816@1|root,COG1816@2|Bacteria	2|Bacteria	F	deaminase activity	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
ZZS2_k127_6775996_20	1089547.KB913013_gene2244	1.488e-39	162.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
ZZS2_k127_6775996_29	1403819.BATR01000097_gene3196	6.348e-07	61.0	2DNHT@1|root,32XKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YHS
ZZS2_k127_6775996_16	1123256.KB907925_gene1300	1.02e-49	181.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1X69P@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
ZZS2_k127_6775996_5	298386.PBPRB1903	3.17e-138	457.0	COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,1XTDS@135623|Vibrionales	135623|Vibrionales	C	Thiol oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
ZZS2_k127_6775996_3	886293.Sinac_6460	2.155e-155	510.0	COG2804@1|root,COG2804@2|Bacteria,2IXSA@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_6775996_8	583355.Caka_1448	5.333e-118	389.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_6775996_2	521674.Plim_0408	3.026e-170	551.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_6775996_14	472759.Nhal_1382	5.061e-58	231.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1WWJK@135613|Chromatiales	135613|Chromatiales	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
ZZS2_k127_6783500_11	1247963.JPHU01000012_gene925	2.069e-40	155.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TWB4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
ZZS2_k127_6783500_14	518766.Rmar_1418	2.156e-31	141.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1FJTB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
ZZS2_k127_6783500_8	595460.RRSWK_06282	4.858e-61	222.0	29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6783500_0	338966.Ppro_0044	2.373e-150	485.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
ZZS2_k127_6783500_23	441620.Mpop_4189	6.071e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria,1JT8I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_6783500_3	243231.GSU3331	2.591e-111	380.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43TCB@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAF987.Gmet_0122	Fer4_9,PK,PK_C
ZZS2_k127_6783500_10	1231241.Mc24_04405	1.365e-40	155.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
ZZS2_k127_6783500_12	886293.Sinac_5143	4.636e-39	149.0	COG0103@1|root,COG0103@2|Bacteria,2J01J@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
ZZS2_k127_6783500_6	589865.DaAHT2_1209	4.09e-71	248.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
ZZS2_k127_6783500_18	215803.DB30_6730	3.026e-07	63.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria,2YW8C@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
ZZS2_k127_6783500_20	1210884.HG799471_gene14668	2.175e-06	61.0	COG1716@1|root,COG1716@2|Bacteria,2IZA4@203682|Planctomycetes	203682|Planctomycetes	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA
ZZS2_k127_6783500_13	1210884.HG799467_gene13330	1.274e-38	160.0	COG0515@1|root,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_6783500_17	309801.trd_A0415	1.002e-07	64.0	COG1595@1|root,COG1595@2|Bacteria,2GBDV@200795|Chloroflexi,27Z17@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_6783500_19	1210884.HG799464_gene10789	4.251e-07	58.0	2E7HG@1|root,331ZY@2|Bacteria,2J0MZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6783500_15	530564.Psta_2772	2.943e-14	83.0	2CNIE@1|root,32SH6@2|Bacteria,2J02V@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6783500_1	331869.BAL199_15703	6.386e-146	472.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,4BPP4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
ZZS2_k127_6783500_2	986075.CathTA2_1978	1.686e-115	399.0	COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
ZZS2_k127_6783500_22	570952.ATVH01000011_gene236	4.41e-05	51.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2V9YM@28211|Alphaproteobacteria,2JUK2@204441|Rhodospirillales	204441|Rhodospirillales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS2_k127_6783500_7	575540.Isop_0271	1.803e-65	239.0	COG0142@1|root,COG0142@2|Bacteria,2IXUE@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS2_k127_6783500_21	1123242.JH636435_gene2587	3.112e-05	57.0	2DSGX@1|root,33G2Z@2|Bacteria,2J509@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6783500_9	1396418.BATQ01000064_gene1598	1.624e-50	206.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,2IUGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
ZZS2_k127_6783500_4	1396141.BATP01000016_gene2844	2.54e-98	359.0	COG0755@1|root,COG0755@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
ZZS2_k127_6783500_5	445972.ANACOL_02018	8.553e-76	263.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
ZZS2_k127_6783500_16	38833.XP_003062370.1	2.436e-08	65.0	COG0705@1|root,KOG2980@2759|Eukaryota,37MHD@33090|Viridiplantae	33090|Viridiplantae	T	RHOMBOID-like protein 12	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
ZZS2_k127_6783562_4	1379698.RBG1_1C00001G0682	1.689e-16	88.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
ZZS2_k127_6783562_1	706587.Desti_4506	2.526e-227	722.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
ZZS2_k127_6783562_3	1500281.JQKZ01000015_gene2139	1.478e-36	151.0	COG3645@1|root,COG3645@2|Bacteria,4NJ37@976|Bacteroidetes,1IMRC@117743|Flavobacteriia,3ZSUD@59732|Chryseobacterium	976|Bacteroidetes	S	DNA-damage-inducible protein D	dinD	-	-	ko:K14623	-	-	-	-	ko00000,ko03400	-	-	-	Bro-N
ZZS2_k127_6783562_2	344747.PM8797T_24351	2.861e-208	658.0	COG3119@1|root,COG3119@2|Bacteria,2J1QK@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_6783562_0	1396141.BATP01000003_gene5073	6.184e-252	801.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_678992_15	996637.SGM_0043	2.001e-07	63.0	COG1366@1|root,COG1366@2|Bacteria,2GUNY@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
ZZS2_k127_678992_6	1267535.KB906767_gene5535	1.065e-50	197.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
ZZS2_k127_678992_12	1384054.N790_00665	3.305e-18	98.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1X4RV@135614|Xanthomonadales	135614|Xanthomonadales	M	UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	rfb303	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
ZZS2_k127_678992_8	1123504.JQKD01000024_gene277	5.079e-38	150.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,4AE0B@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS2_k127_678992_13	251229.Chro_0314	6.097e-12	78.0	2DYCI@1|root,32UUN@2|Bacteria,1G8UW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
ZZS2_k127_678992_11	592031.GCWU000322_00644	6.124e-22	109.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,25W3T@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
ZZS2_k127_678992_5	314230.DSM3645_04255	1.667e-57	211.0	COG0324@1|root,COG0324@2|Bacteria,2IYY6@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
ZZS2_k127_678992_4	756272.Plabr_0624	1.529e-57	226.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
ZZS2_k127_678992_10	1202962.KB907176_gene77	9.176e-33	148.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
ZZS2_k127_678992_17	450851.PHZ_c0696	1.341e-06	60.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2KH37@204458|Caulobacterales	204458|Caulobacterales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
ZZS2_k127_678992_1	1173027.Mic7113_3411	1.295e-81	284.0	COG0463@1|root,COG0463@2|Bacteria,1G153@1117|Cyanobacteria,1H7H6@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
ZZS2_k127_678992_7	1191523.MROS_1306	7.979e-45	188.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
ZZS2_k127_678992_2	864051.BurJ1DRAFT_3187	2.164e-67	261.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria,1KN06@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
ZZS2_k127_678992_16	938709.AUSH02000051_gene200	2.673e-07	64.0	COG1404@1|root,COG3291@1|root,COG3405@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SLH,SdrD_B
ZZS2_k127_678992_9	1128421.JAGA01000003_gene3261	3.06e-33	137.0	COG0241@1|root,COG0241@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	2.7.7.71,3.1.3.82,3.1.3.83	ko:K03273,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771,R09772	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iIT341.HP0860	HAD_2,Hydrolase_like,NTP_transferase,PNK3P
ZZS2_k127_678992_18	1298598.JCM21714_4378	0.0005261	52.0	COG3807@1|root,COG4193@1|root,COG3807@2|Bacteria,COG4193@2|Bacteria,1V1F9@1239|Firmicutes,4HBQV@91061|Bacilli	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHAP,Glucosaminidase,SH3_3,SLH
ZZS2_k127_678992_0	1536769.P40081_06260	5.694e-220	696.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,26UV8@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
ZZS2_k127_678992_3	478741.JAFS01000001_gene1824	2.782e-67	260.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
ZZS2_k127_6792146_5	620914.JH621310_gene55	7.645e-85	295.0	COG2273@1|root,COG5434@1|root,COG2273@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,Glyco_hydro_16,Pectate_lyase_3,RicinB_lectin_2
ZZS2_k127_6792146_12	338966.Ppro_1017	5.486e-06	55.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
ZZS2_k127_6792146_11	530564.Psta_3867	3.731e-08	67.0	2E003@1|root,32VPJ@2|Bacteria,2J09M@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
ZZS2_k127_6792146_3	1382303.JPOM01000001_gene1205	4.044e-117	407.0	COG1262@1|root,COG4301@1|root,COG1262@2|Bacteria,COG4301@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2KFXT@204458|Caulobacterales	204458|Caulobacterales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_33
ZZS2_k127_6792146_4	397948.Cmaq_0585	1.605e-112	385.0	COG0620@1|root,arCOG01876@2157|Archaea,2XPKF@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
ZZS2_k127_6792146_7	1131730.BAVI_15667	5.544e-48	183.0	COG0425@1|root,COG1765@1|root,COG0425@2|Bacteria,COG1765@2|Bacteria,1U9IG@1239|Firmicutes,4IJP4@91061|Bacilli,1ZCSK@1386|Bacillus	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	OsmC,TusA
ZZS2_k127_6792146_6	1203568.HMPREF1484_02087	4.246e-50	180.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
ZZS2_k127_6792146_10	1203568.HMPREF1484_02088	8.104e-12	78.0	2BMJ7@1|root,32G45@2|Bacteria,2H1DR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
ZZS2_k127_6792146_9	452637.Oter_0260	3.801e-38	158.0	COG1305@1|root,COG1305@2|Bacteria,46YS9@74201|Verrucomicrobia,3KA0E@414999|Opitutae	414999|Opitutae	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ZZS2_k127_6792146_2	880072.Desac_2382	2.238e-126	415.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
ZZS2_k127_6792146_0	497964.CfE428DRAFT_5241	1.873e-207	675.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ZZS2_k127_6792146_1	1403819.BATR01000067_gene2010	2.733e-133	429.0	COG2326@1|root,COG2326@2|Bacteria,46UWN@74201|Verrucomicrobia,2IVFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
ZZS2_k127_6792146_8	1037409.BJ6T_58620	1.127e-44	173.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
ZZS2_k127_6811530_4	649638.Trad_1430	1.046e-10	63.0	2E3EN@1|root,32YDN@2|Bacteria,1WKIV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
ZZS2_k127_6811530_5	1454004.AW11_03501	1.854e-05	58.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,1KQFU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
ZZS2_k127_6811530_0	926566.Terro_0195	2.062e-158	550.0	COG0308@1|root,COG0308@2|Bacteria,3Y6V6@57723|Acidobacteria,2JMGB@204432|Acidobacteriia	204432|Acidobacteriia	E	ERAP1-like C-terminal domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
ZZS2_k127_6811530_1	1185876.BN8_00865	6.309e-76	277.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
ZZS2_k127_6811530_3	62928.azo0278	5.224e-12	79.0	2EFNF@1|root,339EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6811530_2	1183438.GKIL_3263	2.469e-29	136.0	COG1470@1|root,COG3391@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,VCBS
ZZS2_k127_6825968_8	1297865.APJD01000006_gene4608	4.417e-06	59.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2TV0X@28211|Alphaproteobacteria,3JXPF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
ZZS2_k127_6825968_2	227377.CBU_1763	1.308e-142	464.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	HTH_36
ZZS2_k127_6825968_1	497964.CfE428DRAFT_2266	1.447e-163	529.0	COG0477@1|root,COG2814@2|Bacteria,46U08@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
ZZS2_k127_6825968_4	1121033.AUCF01000008_gene5678	3.267e-115	388.0	COG1748@1|root,COG1748@2|Bacteria,1MY1G@1224|Proteobacteria,2TU0J@28211|Alphaproteobacteria,2JQ81@204441|Rhodospirillales	204441|Rhodospirillales	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
ZZS2_k127_6825968_5	2340.JV46_08190	1.172e-64	233.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS2_k127_6825968_0	243090.RB5841	9.304e-175	569.0	COG1409@1|root,COG1409@2|Bacteria,2J2E9@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
ZZS2_k127_6825968_7	1210884.HG799463_gene9412	1.711e-07	58.0	COG4692@1|root,COG4692@2|Bacteria,2IX4M@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
ZZS2_k127_6825968_6	344747.PM8797T_24886	1.25e-45	177.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
ZZS2_k127_6825968_3	1121957.ATVL01000014_gene1459	1.97e-118	406.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6845781_5	867903.ThesuDRAFT_00352	2.243e-80	279.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
ZZS2_k127_6845781_8	395494.Galf_2854	3.139e-58	216.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
ZZS2_k127_6845781_3	1123508.JH636447_gene7881	3.465e-95	342.0	COG0515@1|root,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_8,WD40
ZZS2_k127_6845781_13	582515.KR51_00015700	4.497e-22	113.0	COG1262@1|root,COG1262@2|Bacteria,1G4JZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_6845781_16	1112204.GPOL_c37800	1.488e-11	79.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4GDG8@85026|Gordoniaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
ZZS2_k127_6845781_1	335543.Sfum_1982	5.376e-104	371.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42R9P@68525|delta/epsilon subdivisions,2WMSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
ZZS2_k127_6845781_9	543632.JOJL01000004_gene4287	7.803e-45	184.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4DAGT@85008|Micromonosporales	201174|Actinobacteria	E	asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ZZS2_k127_6845781_0	204669.Acid345_3484	2.11e-111	375.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
ZZS2_k127_6845781_4	861299.J421_1561	7.55e-88	295.0	2DB9P@1|root,2Z7Y1@2|Bacteria	2|Bacteria	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
ZZS2_k127_6845781_7	1382356.JQMP01000004_gene149	1.686e-59	214.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,27Y9H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
ZZS2_k127_6845781_2	1144275.COCOR_02602	1.754e-96	330.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2YV07@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
ZZS2_k127_6845781_11	509190.Cseg_0271	1.182e-27	122.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS2_k127_6845781_10	743721.Psesu_1243	1.713e-38	153.0	2DMWE@1|root,32UHT@2|Bacteria,1QCRQ@1224|Proteobacteria,1T8I3@1236|Gammaproteobacteria,1XAS0@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6845781_14	1123508.JH636440_gene2568	7.263e-21	102.0	COG2110@1|root,COG2110@2|Bacteria,2IZMD@203682|Planctomycetes	203682|Planctomycetes	S	Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
ZZS2_k127_6845781_12	511145.b2274	5.336e-26	115.0	2ERBJ@1|root,33IX7@2|Bacteria	2|Bacteria	-	-	yfbO	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6845781_6	1146883.BLASA_2735	2.666e-66	237.0	COG5586@1|root,COG5586@2|Bacteria,2GX58@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
ZZS2_k127_6845781_15	402777.KB235904_gene3508	3.323e-13	83.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1H8BH@1150|Oscillatoriales	1117|Cyanobacteria	CT	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
ZZS2_k127_6845781_17	215803.DB30_7345	1.339e-09	72.0	COG2010@1|root,COG2010@2|Bacteria,1QX97@1224|Proteobacteria,43C2C@68525|delta/epsilon subdivisions,2X7CY@28221|Deltaproteobacteria,2Z3FK@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6847581_9	573065.Astex_3197	1.757e-05	54.0	2B9DW@1|root,322RP@2|Bacteria,1RK47@1224|Proteobacteria,2UY0U@28211|Alphaproteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6847581_1	396588.Tgr7_2703	2.746e-115	385.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X1FE@135613|Chromatiales	135613|Chromatiales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4
ZZS2_k127_6847581_2	1123073.KB899241_gene2570	3.713e-79	300.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1X40U@135614|Xanthomonadales	135614|Xanthomonadales	J	Oxidoreductase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ZZS2_k127_6847581_0	502025.Hoch_5294	0.0	1106.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,42M1V@68525|delta/epsilon subdivisions,2WMFC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
ZZS2_k127_6847581_6	744979.R2A130_3115	5.937e-08	66.0	COG1404@1|root,COG3210@1|root,COG4386@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4386@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
ZZS2_k127_6847581_3	477974.Daud_2054	1.167e-29	127.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,260UN@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
ZZS2_k127_6847581_4	378806.STAUR_2097	4.908e-14	86.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1Q3EZ@1224|Proteobacteria,4396Y@68525|delta/epsilon subdivisions,2X4DS@28221|Deltaproteobacteria,2YYTR@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
ZZS2_k127_6847581_5	869210.Marky_1534	1.173e-08	68.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS2_k127_6847581_7	329726.AM1_4750	5.865e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
ZZS2_k127_6847581_8	344747.PM8797T_07989	4.083e-06	57.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_6850694_1	33035.JPJF01000051_gene798	4.628e-87	297.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
ZZS2_k127_6850694_4	886293.Sinac_7506	1.916e-09	66.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_6850694_3	290397.Adeh_1104	5.087e-11	72.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42U0Y@68525|delta/epsilon subdivisions,2WR00@28221|Deltaproteobacteria,2Z08B@29|Myxococcales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
ZZS2_k127_6850694_2	234267.Acid_5182	2.657e-11	69.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
ZZS2_k127_6850694_0	237368.SCABRO_03706	7.772e-179	578.0	COG0532@1|root,COG0532@2|Bacteria,2IXYU@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
ZZS2_k127_6930511_0	575540.Isop_2728	2.329e-197	645.0	COG2766@1|root,COG2766@2|Bacteria,2IXPA@203682|Planctomycetes	203682|Planctomycetes	T	PrkA serine protein kinase C-terminal domain	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
ZZS2_k127_6930511_5	469383.Cwoe_1835	2.072e-16	91.0	COG2234@1|root,COG2234@2|Bacteria,2HNRS@201174|Actinobacteria,4CPZD@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_6930511_2	1382359.JIAL01000001_gene1834	1.369e-33	150.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS2_k127_6930511_6	1449347.JQLN01000005_gene3728	8.043e-11	72.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,2M0AS@2063|Kitasatospora	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS2_k127_6930511_4	713587.THITH_03440	9.131e-25	113.0	COG2442@1|root,COG2442@2|Bacteria,1N7GJ@1224|Proteobacteria,1SCUP@1236|Gammaproteobacteria,1WZKZ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
ZZS2_k127_6930511_3	221360.RS9917_11635	4.865e-31	125.0	COG4634@1|root,COG4634@2|Bacteria,1GJHB@1117|Cyanobacteria,1H1T3@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_6930511_1	243090.RB10165	8.841e-103	357.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
ZZS2_k127_7014184_1	1044.EH31_11950	9.718e-156	497.0	COG1082@1|root,COG1082@2|Bacteria,1MVSJ@1224|Proteobacteria,2TV5J@28211|Alphaproteobacteria,2K28J@204457|Sphingomonadales	204457|Sphingomonadales	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
ZZS2_k127_7014184_10	595460.RRSWK_01928	2.762e-51	210.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,WD40
ZZS2_k127_7014184_9	864051.BurJ1DRAFT_1416	1.68e-55	214.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,2WEJM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7014184_6	404589.Anae109_2914	9.684e-94	321.0	COG2133@1|root,COG2133@2|Bacteria,1PEHH@1224|Proteobacteria,437W5@68525|delta/epsilon subdivisions,2X35P@28221|Deltaproteobacteria,2YUDG@29|Myxococcales	28221|Deltaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7014184_18	344747.PM8797T_31815	1.3e-09	67.0	COG1595@1|root,COG1595@2|Bacteria,2J02A@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_7014184_2	314230.DSM3645_10052	5.938e-132	440.0	COG0457@1|root,COG0457@2|Bacteria,2IXTF@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS2_k127_7014184_11	1203611.KB894543_gene1876	1.426e-49	182.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,2FP0R@200643|Bacteroidia	976|Bacteroidetes	FJ	Cytidine and deoxycytidylate deaminase zinc-binding region	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
ZZS2_k127_7014184_20	743720.Psefu_2281	0.000372	51.0	2F5NU@1|root,33Y7R@2|Bacteria,1NVJZ@1224|Proteobacteria,1SNVZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7014184_5	234267.Acid_3643	4.57e-101	353.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	LpoB,Sel1
ZZS2_k127_7014184_3	925409.KI911562_gene1912	4.015e-127	417.0	COG1373@1|root,COG1373@2|Bacteria,4NEMX@976|Bacteroidetes,1IRG9@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
ZZS2_k127_7014184_4	765911.Thivi_0089	6.93e-116	384.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1WXI9@135613|Chromatiales	135613|Chromatiales	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
ZZS2_k127_7014184_16	1123508.JH636442_gene4313	3.063e-20	107.0	COG1262@1|root,COG1262@2|Bacteria,2IZ7E@203682|Planctomycetes	2|Bacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14,Pkinase
ZZS2_k127_7014184_7	1396418.BATQ01000186_gene2167	3.078e-88	321.0	COG0515@1|root,COG0515@2|Bacteria,46X96@74201|Verrucomicrobia,2IV2P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS2_k127_7014184_19	1192034.CAP_4867	7.068e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,2YU62@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
ZZS2_k127_7014184_12	76114.ebA169	5.432e-44	184.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,2KUB6@206389|Rhodocyclales	206389|Rhodocyclales	ET	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_7014184_13	485916.Dtox_0784	6.598e-24	106.0	COG2940@1|root,COG2940@2|Bacteria,1V4EX@1239|Firmicutes	1239|Firmicutes	S	Lysine methyltransferase	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
ZZS2_k127_7014184_0	1123508.JH636444_gene5160	6.961e-299	951.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
ZZS2_k127_7014184_14	1121324.CLIT_13c01090	2.523e-22	111.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
ZZS2_k127_7014184_15	941449.dsx2_0703	6.015e-21	100.0	COG1309@1|root,COG1309@2|Bacteria,1PGI1@1224|Proteobacteria,43A97@68525|delta/epsilon subdivisions,2X09X@28221|Deltaproteobacteria,2MBF3@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_7014184_17	85643.Tmz1t_2713	1.001e-12	82.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria	28216|Betaproteobacteria	M	RND efflux system, outer membrane lipoprotein	oprM	-	-	ko:K18139,ko:K18903	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00698,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,1.B.17.3.3,2.A.6.2	-	-	OEP
ZZS2_k127_7014184_8	589865.DaAHT2_1767	4.425e-58	216.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,42VRI@68525|delta/epsilon subdivisions,2WRUV@28221|Deltaproteobacteria,2MPAI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ZZS2_k127_702231_0	525904.Tter_2106	2.159e-12	79.0	COG0308@1|root,COG3103@1|root,COG0308@2|Bacteria,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.4.11.2,3.4.21.96	ko:K01256,ko:K01361	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_MA_2,SH3_3,SpoIID
ZZS2_k127_7058996_4	1123072.AUDH01000002_gene2560	1.122e-13	73.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2JQBN@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_7058996_0	756272.Plabr_4330	1.83e-160	524.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
ZZS2_k127_7058996_1	1266914.ATUK01000012_gene147	6.247e-35	152.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1SZ84@1236|Gammaproteobacteria,1WXUW@135613|Chromatiales	135613|Chromatiales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS2_k127_7058996_3	1094980.Mpsy_1538	4.652e-18	101.0	COG2304@1|root,COG4934@1|root,arCOG02902@2157|Archaea,arCOG03665@2157|Archaea	2157|Archaea	O	tripeptidyl-peptidase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,Peptidase_S8,Pro-kuma_activ,VWA,VWA_2
ZZS2_k127_7058996_6	59538.XP_005967471.1	7.088e-05	48.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,4804V@7711|Chordata,497Y0@7742|Vertebrata,3JBZ5@40674|Mammalia,4IXTJ@91561|Cetartiodactyla	33208|Metazoa	F	Carbamoyl-phosphate synthase	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,DapB_C,DapB_N,GATase,MGS
ZZS2_k127_7058996_2	1168059.KB899087_gene2791	1.42e-21	109.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2U9WD@28211|Alphaproteobacteria,3EZAU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
ZZS2_k127_7058996_5	471855.Shel_09840	1.351e-09	61.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CV46@84998|Coriobacteriia	84998|Coriobacteriia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ZZS2_k127_7111494_2	926550.CLDAP_21630	4.702e-104	349.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS2_k127_7111494_3	478741.JAFS01000002_gene80	1.877e-59	216.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	ydgH	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
ZZS2_k127_7111494_4	926556.Echvi_0208	5.219e-47	178.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS2_k127_7111494_10	497964.CfE428DRAFT_0438	2.938e-05	57.0	COG1520@1|root,COG1572@1|root,COG3227@1|root,COG3391@1|root,COG4782@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG3391@2|Bacteria,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	DUF900,FTP,Peptidase_M36
ZZS2_k127_7111494_1	1121012.AUKX01000003_gene1491	3.983e-154	494.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1I009@117743|Flavobacteriia,23GV6@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS2_k127_7111494_0	485913.Krac_12092	3.24e-231	726.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
ZZS2_k127_7111494_5	443144.GM21_0571	2.947e-38	147.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
ZZS2_k127_7115883_2	1283299.AUKG01000001_gene3471	2.557e-16	93.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4CT8A@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
ZZS2_k127_7115883_0	575540.Isop_1218	9.465e-167	553.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7115883_1	575540.Isop_1217	6.595e-107	357.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_7129343_6	234267.Acid_7897	3.078e-36	160.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7129343_3	204669.Acid345_0453	4.63e-88	295.0	COG0243@1|root,COG0243@2|Bacteria,3Y7US@57723|Acidobacteria	57723|Acidobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
ZZS2_k127_7129343_0	204669.Acid345_0454	0.0	1332.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3Y47M@57723|Acidobacteria	57723|Acidobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
ZZS2_k127_7129343_1	204669.Acid345_0455	4.884e-276	917.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD
ZZS2_k127_7129343_4	404589.Anae109_3041	4.283e-65	234.0	COG3058@1|root,COG3058@2|Bacteria,1NK06@1224|Proteobacteria,42VNJ@68525|delta/epsilon subdivisions,2WS9J@28221|Deltaproteobacteria,2Z2AD@29|Myxococcales	28221|Deltaproteobacteria	O	Necessary for formate dehydrogenase activity	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
ZZS2_k127_7129343_2	204669.Acid345_0452	5.163e-132	436.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	204432|Acidobacteriia	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
ZZS2_k127_7129343_5	247490.KSU1_C1665	4.197e-41	177.0	2EBFT@1|root,335GE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7194901_11	861299.J421_0281	1.718e-12	76.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
ZZS2_k127_7194901_12	443598.AUFA01000018_gene7515	4.18e-10	71.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3JQQI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	MA20_07235	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_7194901_2	1123388.AQWU01000051_gene1444	1.106e-78	277.0	COG0232@1|root,COG0232@2|Bacteria,1WI39@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the dGTPase family. Type 2 subfamily	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
ZZS2_k127_7194901_0	344747.PM8797T_07137	2.318e-129	424.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes	203682|Planctomycetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
ZZS2_k127_7194901_1	1121405.dsmv_1452	9.527e-125	412.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MI37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
ZZS2_k127_7194901_3	1267533.KB906736_gene1328	1.442e-58	233.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS2_k127_7194901_4	1121272.KB903249_gene2169	5.102e-57	229.0	COG2373@1|root,COG2374@1|root,COG3250@1|root,COG5492@1|root,COG2373@2|Bacteria,COG2374@2|Bacteria,COG3250@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria,4DF33@85008|Micromonosporales	201174|Actinobacteria	E	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
ZZS2_k127_7194901_6	583345.Mmol_1915	3.074e-34	134.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2VU3F@28216|Betaproteobacteria,2KN8D@206350|Nitrosomonadales	206350|Nitrosomonadales	P	PFAM small multidrug resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
ZZS2_k127_7194901_5	278957.ABEA03000011_gene3348	6.291e-53	191.0	29A26@1|root,2ZX3K@2|Bacteria,46XTQ@74201|Verrucomicrobia,3K806@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7194901_9	240016.ABIZ01000001_gene2346	6.771e-16	88.0	2EU5N@1|root,33MN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7194901_8	1089545.KB913037_gene872	1.44e-16	81.0	2EH45@1|root,33AW4@2|Bacteria,2GZ28@201174|Actinobacteria,4ECZ7@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7194901_13	436229.JOEH01000019_gene6693	1.11e-05	57.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,2NFUY@228398|Streptacidiphilus	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
ZZS2_k127_7194901_10	1394178.AWOO02000011_gene4017	1.657e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EHHP@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS2_k127_7243655_3	1123508.JH636439_gene990	2.096e-27	118.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS2_k127_7243655_4	1449976.KALB_114	3.397e-06	60.0	COG2425@1|root,COG2425@2|Bacteria,2GK1P@201174|Actinobacteria,4DZUY@85010|Pseudonocardiales	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
ZZS2_k127_7243655_1	1453501.JELR01000002_gene810	7.13e-47	174.0	COG4898@1|root,COG4898@2|Bacteria,1RHGW@1224|Proteobacteria,1S7UZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
ZZS2_k127_7243655_2	1265313.HRUBRA_01343	7.067e-31	132.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
ZZS2_k127_7243655_5	72019.SARC_11747T0	4.096e-06	60.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta	33154|Opisthokonta	T	calcium ion binding	-	-	-	ko:K02599	ko01522,ko04320,ko04330,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002	-	-	-	EGF,SRCR,hEGF
ZZS2_k127_7243655_0	1123508.JH636452_gene7057	1.804e-53	200.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2J2J0@203682|Planctomycetes	203682|Planctomycetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT,VWA_3
ZZS2_k127_724878_11	643648.Slip_2222	1.153e-40	154.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,42JWP@68298|Syntrophomonadaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
ZZS2_k127_724878_15	391937.NA2_13535	1.797e-30	129.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria,43K70@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
ZZS2_k127_724878_8	575540.Isop_2097	4.145e-50	184.0	COG0098@1|root,COG0098@2|Bacteria,2IZ7J@203682|Planctomycetes	203682|Planctomycetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
ZZS2_k127_724878_14	1410638.JHXJ01000008_gene395	2.929e-36	144.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
ZZS2_k127_724878_2	237368.SCABRO_03487	7.652e-120	399.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
ZZS2_k127_724878_7	867903.ThesuDRAFT_00579	1.837e-58	230.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WCG7@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
ZZS2_k127_724878_18	572547.Amico_0651	5.335e-06	57.0	COG0361@1|root,COG0361@2|Bacteria,3TBCB@508458|Synergistetes	508458|Synergistetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS2_k127_724878_17	754252.PFREUD_06030	1.466e-10	67.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
ZZS2_k127_724878_10	857293.CAAU_1201	3.118e-43	160.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,36IR2@31979|Clostridiaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
ZZS2_k127_724878_9	756272.Plabr_2080	3.555e-47	176.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
ZZS2_k127_724878_6	264732.Moth_2432	5.138e-66	231.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
ZZS2_k127_724878_3	247490.KSU1_C1236	7.357e-112	371.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
ZZS2_k127_724878_16	1082931.KKY_1646	1.539e-29	123.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,3N6TQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
ZZS2_k127_724878_0	1121472.AQWN01000002_gene2301	2.207e-308	981.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS2_k127_724878_1	926569.ANT_18040	1.523e-138	451.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_724878_13	1352941.M877_01615	6.179e-39	158.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS2_k127_724878_5	767434.Fraau_2115	1.583e-77	281.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS2_k127_724878_12	396588.Tgr7_1037	3.638e-40	153.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1WXZ8@135613|Chromatiales	135613|Chromatiales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
ZZS2_k127_724878_4	886293.Sinac_4798	1.468e-105	358.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_7259178_0	136993.KB900626_gene3898	1.447e-237	763.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,36X8N@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
ZZS2_k127_7259178_4	1208323.B30_01815	1.313e-71	248.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
ZZS2_k127_7259178_11	497321.C664_06458	0.0003914	53.0	2DN0A@1|root,32UPR@2|Bacteria,1N1BR@1224|Proteobacteria,2VVZG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7259178_1	1121438.JNJA01000012_gene1569	8.011e-144	478.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MAFI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
ZZS2_k127_7259178_9	1121405.dsmv_1897	1.252e-07	58.0	COG1225@1|root,COG1225@2|Bacteria,1NN23@1224|Proteobacteria,42XJF@68525|delta/epsilon subdivisions,2WTAE@28221|Deltaproteobacteria,2MNXB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AhpC/TSA antioxidant enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
ZZS2_k127_7259178_3	640512.BC1003_3996	3.265e-88	308.0	COG0662@1|root,COG0662@2|Bacteria,1NX8W@1224|Proteobacteria,2WI0U@28216|Betaproteobacteria,1K2VP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7259178_7	1116232.AHBF01000066_gene8632	2.155e-27	125.0	2E5G9@1|root,3307Y@2|Bacteria,2IGBZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7259178_10	344747.PM8797T_24886	3.126e-06	53.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
ZZS2_k127_7259178_6	33898.JRHJ01000078_gene1118	6.699e-47	180.0	COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	coxS_1	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2
ZZS2_k127_7259178_2	886293.Sinac_6836	8.136e-127	441.0	COG1529@1|root,COG1529@2|Bacteria,2IYIN@203682|Planctomycetes	203682|Planctomycetes	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS2_k127_7259178_5	391625.PPSIR1_41939	1.771e-62	230.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2YY4R@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
ZZS2_k127_7262221_0	1234364.AMSF01000056_gene1202	0.0	1318.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1X3FZ@135614|Xanthomonadales	135614|Xanthomonadales	O	COG0542 ATPases with chaperone activity, ATP-binding subunit	clpB1	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
ZZS2_k127_7262221_1	439235.Dalk_4469	2.183e-30	141.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2X5P3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS2_k127_7262221_2	685778.AORL01000021_gene664	1.892e-17	93.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,2U433@28211|Alphaproteobacteria,2KA3J@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_7275875_1	1121920.AUAU01000006_gene306	1.301e-198	642.0	COG1506@1|root,COG1506@2|Bacteria,3Y2HK@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
ZZS2_k127_7275875_3	237368.SCABRO_01223	1.162e-43	178.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
ZZS2_k127_7275875_2	706587.Desti_2239	3.341e-104	354.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS2_k127_7275875_5	1121440.AUMA01000015_gene1776	7.506e-34	147.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42QEJ@68525|delta/epsilon subdivisions,2X6C2@28221|Deltaproteobacteria,2MH13@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
ZZS2_k127_7275875_6	1142394.PSMK_04940	2.579e-30	135.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K07273	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_2,Amidase_3,DUF1906,Glyco_hydro_25,LysM,Peptidase_M23
ZZS2_k127_7275875_9	326427.Cagg_2419	9.782e-07	58.0	COG0664@1|root,COG2172@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,376A8@32061|Chloroflexia	32061|Chloroflexia	KT	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE,cNMP_binding
ZZS2_k127_7275875_4	269799.Gmet_2818	2.218e-42	174.0	COG0784@1|root,COG2202@1|root,COG2208@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,1NC9X@1224|Proteobacteria,43C4D@68525|delta/epsilon subdivisions,2X7EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domains REC, PAS, PAS, PP2C	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_9,Response_reg,SpoIIE
ZZS2_k127_7275875_7	748280.NH8B_3990	1.084e-29	132.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KTJ0@206351|Neisseriales	206351|Neisseriales	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS2_k127_7275875_8	1110502.TMO_0754	6.941e-09	68.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2JPD5@204441|Rhodospirillales	204441|Rhodospirillales	V	MatE	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
ZZS2_k127_7275875_0	1239962.C943_03159	7.895e-242	762.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ZZS2_k127_7294684_5	861299.J421_2314	3.726e-134	443.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS2_k127_7294684_10	926569.ANT_10670	5.418e-68	255.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,2G6PW@200795|Chloroflexi	200795|Chloroflexi	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,Dna2
ZZS2_k127_7294684_3	926550.CLDAP_00380	2.817e-177	591.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
ZZS2_k127_7294684_4	234267.Acid_2163	3.221e-177	570.0	COG1215@1|root,COG1215@2|Bacteria,3Y74D@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_7294684_29	344747.PM8797T_00397	0.0008959	53.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
ZZS2_k127_7294684_6	1280944.HY17_19045	1.692e-129	428.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria,43W4Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377,ko:K16554	ko00051,ko00520,ko01100,ko05111,map00051,map00520,map01100,map05111	-	R05692	RC01014	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	Epimerase
ZZS2_k127_7294684_1	1158146.KB907124_gene2082	2.158e-187	593.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1WWR3@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
ZZS2_k127_7294684_2	1125863.JAFN01000001_gene929	6.05e-184	598.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
ZZS2_k127_7294684_11	159087.Daro_2705	2.72e-53	199.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,2KUC0@206389|Rhodocyclales	206389|Rhodocyclales	I	phytoene	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
ZZS2_k127_7294684_16	330214.NIDE1520	2.3e-37	159.0	COG1562@1|root,COG1562@2|Bacteria,3J17J@40117|Nitrospirae	40117|Nitrospirae	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
ZZS2_k127_7294684_13	1142394.PSMK_19780	7.489e-46	185.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	1.3.5.5	ko:K02293	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04786,R04787,R07510,R09652,R09653,R09654	RC01214,RC01958,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
ZZS2_k127_7294684_21	1123508.JH636441_gene3405	4.646e-07	63.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	xynX5	-	-	-	-	-	-	-	-	-	-	-	Big_2,SLH,VWA_2
ZZS2_k127_7294684_27	240292.Ava_3508	0.0001535	55.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G3GI@1117|Cyanobacteria,1HM4X@1161|Nostocales	1117|Cyanobacteria	CT	Ntpase (Nacht family)	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
ZZS2_k127_7294684_8	530564.Psta_1631	9.137e-85	291.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,2IXEW@203682|Planctomycetes	203682|Planctomycetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
ZZS2_k127_7294684_20	1210884.HG799462_gene8668	2.736e-07	63.0	COG2304@1|root,COG2304@2|Bacteria,2IZSI@203682|Planctomycetes	203682|Planctomycetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
ZZS2_k127_7294684_26	1227739.Hsw_0986	7.86e-05	56.0	COG2831@1|root,COG2931@1|root,COG2831@2|Bacteria,COG2931@2|Bacteria,4PPJE@976|Bacteroidetes,47YRQ@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_7294684_22	1125971.ASJB01000030_gene1049	8.455e-07	62.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
ZZS2_k127_7294684_19	1121918.ARWE01000001_gene2901	4.869e-08	64.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43U7Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_7294684_12	1122222.AXWR01000037_gene289	5.473e-51	203.0	COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
ZZS2_k127_7294684_7	309807.SRU_1324	9.873e-91	314.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1FIQP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.88	ko:K00812,ko:K10907,ko:K14287	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08618	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS2_k127_7294684_9	997346.HMPREF9374_2156	1.491e-68	262.0	COG1463@1|root,COG2120@1|root,COG1463@2|Bacteria,COG2120@2|Bacteria,1UYPV@1239|Firmicutes,4HCT3@91061|Bacilli,27CPN@186824|Thermoactinomycetaceae	91061|Bacilli	Q	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,PIG-L
ZZS2_k127_7294684_24	877455.Metbo_0470	9.796e-06	59.0	COG1413@1|root,arCOG06468@1|root,arCOG02966@2157|Archaea,arCOG06468@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
ZZS2_k127_7294684_15	357808.RoseRS_4461	2.884e-38	151.0	COG4636@1|root,COG4636@2|Bacteria,2G8R4@200795|Chloroflexi	200795|Chloroflexi	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS2_k127_7294684_0	391625.PPSIR1_35847	2.066e-198	629.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
ZZS2_k127_7294684_14	882083.SacmaDRAFT_1374	2.086e-44	174.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4DZK1@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_7294684_17	379731.PST_2570	8.691e-32	137.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1Z0NX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
ZZS2_k127_7294684_18	671143.DAMO_1734	5.354e-29	132.0	COG1419@1|root,COG1419@2|Bacteria,2NRY5@2323|unclassified Bacteria	2|Bacteria	N	Flagellar biosynthesis protein flhF	flhF	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
ZZS2_k127_7294684_25	404380.Gbem_3843	2.604e-05	56.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.13.3,3.1.3.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02658,ko:K03413,ko:K07315	ko00230,ko02020,ko02025,ko02030,ko04113,ko04213,map00230,map02020,map02025,map02030,map04113,map04213	M00506,M00507,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS2_k127_7294684_23	522306.CAP2UW1_3830	3.214e-06	49.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2VHR3@28216|Betaproteobacteria,1KQTY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS2_k127_7368677_0	485913.Krac_2128	1.685e-204	644.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
ZZS2_k127_7368677_18	425104.Ssed_2991	2.937e-25	119.0	COG0463@1|root,COG0463@2|Bacteria,1QFUD@1224|Proteobacteria,1TD4S@1236|Gammaproteobacteria,2QDXE@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_7368677_14	370438.PTH_1084	1.152e-36	159.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,266SB@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
ZZS2_k127_7368677_6	640081.Dsui_1727	1.553e-56	207.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria,2KV2Y@206389|Rhodocyclales	206389|Rhodocyclales	N	flagellar motor	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
ZZS2_k127_7368677_22	264462.Bd0145	3.384e-12	76.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WKIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
ZZS2_k127_7368677_3	485913.Krac_2131	1.131e-84	309.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS2_k127_7368677_4	485913.Krac_2147	1.083e-83	288.0	COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi	2|Bacteria	I	PFAM Enoyl-CoA hydratase isomerase	MA20_38145	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS2_k127_7368677_28	1394178.AWOO02000031_gene4831	0.0007624	50.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4EJRM@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_7368677_8	1210884.HG799463_gene9428	5.461e-53	216.0	COG0515@1|root,COG0515@2|Bacteria,2IY73@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16
ZZS2_k127_7368677_15	765420.OSCT_0910	2.512e-34	149.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
ZZS2_k127_7368677_13	765420.OSCT_0910	7.33e-39	165.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
ZZS2_k127_7368677_10	1068978.AMETH_3671	2.589e-40	159.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria,4E07R@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
ZZS2_k127_7368677_21	530564.Psta_2158	1.858e-15	79.0	COG0267@1|root,COG0267@2|Bacteria,2J0Q2@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
ZZS2_k127_7368677_9	1184267.A11Q_2332	1.723e-43	172.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2MUQI@213481|Bdellovibrionales,2WM7E@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	PFAM NAD-dependent epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
ZZS2_k127_7368677_25	240016.ABIZ01000001_gene4878	1.833e-07	63.0	COG3209@1|root,COG3266@1|root,COG4782@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG4782@2|Bacteria,46S8F@74201|Verrucomicrobia,2IV48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
ZZS2_k127_7368677_2	1242864.D187_001825	4.817e-117	392.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2WJS3@28221|Deltaproteobacteria,2YXB6@29|Myxococcales	28221|Deltaproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
ZZS2_k127_7368677_1	215803.DB30_5758	6.816e-144	499.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2YWNV@29|Myxococcales	28221|Deltaproteobacteria	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
ZZS2_k127_7368677_12	765420.OSCT_0620	2.292e-39	166.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi,3754Y@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_7368677_19	1192034.CAP_0904	8.173e-21	105.0	2A4R8@1|root,30TCM@2|Bacteria,1PD5K@1224|Proteobacteria,43DYZ@68525|delta/epsilon subdivisions,2WZ8R@28221|Deltaproteobacteria,2Z1KF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TerB
ZZS2_k127_7368677_26	760568.Desku_0493	2.715e-07	60.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7368677_5	667632.KB890164_gene2212	6.084e-69	246.0	COG0840@1|root,COG1366@1|root,COG0840@2|Bacteria,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria,2VNVR@28216|Betaproteobacteria,1K26J@119060|Burkholderiaceae	28216|Betaproteobacteria	T	RsbT co-antagonist protein rsbRD N-terminal domain	rsbRA	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
ZZS2_k127_7368677_11	530564.Psta_2697	7.843e-40	167.0	COG1413@1|root,COG1520@1|root,COG1413@2|Bacteria,COG1520@2|Bacteria,2J3VN@203682|Planctomycetes	2|Bacteria	C	HEAT repeats	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	DNA_alkylation,HEAT_2,MFS_1,PQQ_2,cNMP_binding
ZZS2_k127_7368677_20	243090.RB12730	7.29e-17	93.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7368677_29	1114964.L485_15695	0.0009031	51.0	COG5010@1|root,COG5010@2|Bacteria,1R7S3@1224|Proteobacteria,2TUMP@28211|Alphaproteobacteria,2K076@204457|Sphingomonadales	204457|Sphingomonadales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
ZZS2_k127_7368677_17	523791.Kkor_0735	2.099e-26	116.0	COG1670@1|root,COG1670@2|Bacteria,1RC7M@1224|Proteobacteria,1SZBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS2_k127_7368677_16	1183438.GKIL_2249	1.153e-31	136.0	COG3555@1|root,COG3555@2|Bacteria,1G0W9@1117|Cyanobacteria	1117|Cyanobacteria	O	Aspartyl asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
ZZS2_k127_7368677_24	1380394.JADL01000002_gene1436	2.057e-08	68.0	COG1595@1|root,COG1595@2|Bacteria,1RFN0@1224|Proteobacteria,2U8N2@28211|Alphaproteobacteria,2JYMB@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7406339_3	588596.U9U9B0	0.0002731	53.0	COG0790@1|root,KOG1550@2759|Eukaryota	588596.U9U9B0|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7406339_2	880073.Calab_1826	4.933e-12	79.0	2C05R@1|root,2ZCQ7@2|Bacteria	2|Bacteria	S	PFAM Endonuclease Exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7406339_0	179408.Osc7112_4905	1.802e-58	217.0	COG0500@1|root,COG2226@2|Bacteria,1GQXS@1117|Cyanobacteria,1HI4R@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_7406339_1	458817.Shal_0054	7.548e-16	91.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,1SK9K@1236|Gammaproteobacteria,2QBCN@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
ZZS2_k127_7410716_1	575540.Isop_3619	5.551e-104	347.0	COG1680@1|root,COG2173@1|root,COG1680@2|Bacteria,COG2173@2|Bacteria,2IWSU@203682|Planctomycetes	203682|Planctomycetes	MV	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Peptidase_M15
ZZS2_k127_7410716_0	1045855.DSC_13420	7.579e-154	497.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1X3KV@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ZZS2_k127_7410716_2	290397.Adeh_0078	2.928e-30	123.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7477140_27	694440.JOMF01000004_gene1116	0.0001062	55.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
ZZS2_k127_7477140_2	502025.Hoch_6690	6.687e-162	531.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WNAS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_7477140_22	1123242.JH636434_gene4732	8.611e-24	105.0	COG1725@1|root,COG1725@2|Bacteria,2J1HF@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
ZZS2_k127_7477140_15	497964.CfE428DRAFT_0687	2.039e-47	186.0	COG1131@1|root,COG1131@2|Bacteria,46U5D@74201|Verrucomicrobia	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_7477140_16	28229.ND2E_4159	5.901e-46	190.0	COG0793@1|root,COG1409@1|root,COG0793@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	tri1	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.1.4.53	ko:K03651,ko:K08676	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
ZZS2_k127_7477140_28	886293.Sinac_1543	0.0001952	53.0	COG2314@1|root,COG2314@2|Bacteria,2J0G7@203682|Planctomycetes	203682|Planctomycetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7477140_9	247490.KSU1_C0546	9.693e-73	271.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,Metallophos,Pur_ac_phosph_N
ZZS2_k127_7477140_25	700598.Niako_1654	5.644e-08	66.0	COG5492@1|root,COG5492@2|Bacteria,4NT99@976|Bacteroidetes	976|Bacteroidetes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CBM9_1,DM13,DUF4979,Pectate_lyase_3
ZZS2_k127_7477140_11	272942.RCAP_rcc03098	9.488e-53	200.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,1FB3H@1060|Rhodobacter	28211|Alphaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
ZZS2_k127_7477140_0	635013.TherJR_0243	2.149e-304	958.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS2_k127_7477140_6	521674.Plim_0763	9.33e-82	287.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
ZZS2_k127_7477140_23	592015.HMPREF1705_00208	1.298e-22	106.0	COG3880@1|root,COG3880@2|Bacteria,3TBG4@508458|Synergistetes	508458|Synergistetes	S	PFAM UvrB uvrC	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
ZZS2_k127_7477140_13	278963.ATWD01000001_gene1961	2.16e-50	201.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS2_k127_7477140_1	1267535.KB906767_gene447	1.526e-170	570.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
ZZS2_k127_7477140_21	247490.KSU1_D0515	8.627e-28	117.0	COG1259@1|root,COG1259@2|Bacteria,2IZNE@203682|Planctomycetes	203682|Planctomycetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
ZZS2_k127_7477140_10	1101190.ARWB01000001_gene269	8.383e-63	229.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2TV9J@28211|Alphaproteobacteria,36Y0X@31993|Methylocystaceae	28211|Alphaproteobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
ZZS2_k127_7477140_12	575540.Isop_3493	1.281e-51	205.0	COG0063@1|root,COG0063@2|Bacteria,2IYWH@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
ZZS2_k127_7477140_26	575540.Isop_1549	9.517e-06	57.0	2A5UW@1|root,30UKM@2|Bacteria,2IZAT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7477140_8	204669.Acid345_4573	3.681e-73	257.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria,2JI6J@204432|Acidobacteriia	204432|Acidobacteriia	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
ZZS2_k127_7477140_14	290397.Adeh_2613	2.692e-48	192.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
ZZS2_k127_7477140_20	1142394.PSMK_14770	1.85e-35	149.0	COG1560@1|root,COG1560@2|Bacteria,2IY7N@203682|Planctomycetes	203682|Planctomycetes	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
ZZS2_k127_7477140_3	1380394.JADL01000026_gene4735	5.064e-147	483.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2JQDT@204441|Rhodospirillales	204441|Rhodospirillales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
ZZS2_k127_7477140_29	90814.KL370891_gene780	0.0003634	47.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7477140_5	290397.Adeh_0234	6.918e-108	376.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42Q14@68525|delta/epsilon subdivisions,2WJ8C@28221|Deltaproteobacteria,2YX9F@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
ZZS2_k127_7477140_17	583355.Caka_1800	1.252e-38	161.0	COG2042@1|root,COG2042@2|Bacteria	2|Bacteria	S	rRNA processing	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	DTW,Ribo_biogen_C
ZZS2_k127_7477140_18	247490.KSU1_C0795	1.296e-38	165.0	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS2_k127_7477140_24	1178482.BJB45_20685	5.273e-15	87.0	COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,1XK5R@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
ZZS2_k127_7477140_4	1356852.N008_13820	1.573e-128	432.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
ZZS2_k127_7477140_7	378806.STAUR_8177	9.835e-74	282.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pkinase_Tyr,WD40
ZZS2_k127_7477140_19	717606.PaecuDRAFT_2033	3.836e-38	161.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS2_k127_7511114_6	861299.J421_1115	8.683e-57	227.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7511114_7	1121405.dsmv_1913	6.547e-42	168.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2MHWG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ZZS2_k127_7511114_10	33876.JNXY01000007_gene8358	4.452e-07	62.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4DAYR@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
ZZS2_k127_7511114_2	1210884.HG799463_gene9717	2.141e-112	396.0	COG1262@1|root,COG1262@2|Bacteria,2IZNJ@203682|Planctomycetes	203682|Planctomycetes	CO	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
ZZS2_k127_7511114_0	313606.M23134_02396	7.02e-174	555.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
ZZS2_k127_7511114_4	1123228.AUIH01000005_gene700	5.68e-78	265.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,1XIB2@135619|Oceanospirillales	135619|Oceanospirillales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
ZZS2_k127_7511114_5	592029.DDD_1870	1.645e-75	260.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia,3HKB5@363408|Nonlabens	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
ZZS2_k127_7511114_8	322710.Avin_14610	1.226e-36	159.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
ZZS2_k127_7511114_1	1453500.AT05_07560	5.079e-117	391.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
ZZS2_k127_7511114_3	1203611.KB894551_gene937	3.432e-101	347.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,22U7U@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
ZZS2_k127_7511114_11	493475.GARC_5136	3.484e-06	53.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP-7	-	-	-	-	-	-	-	-	-	-	-	PP-binding
ZZS2_k127_7511114_9	106370.Francci3_3661	2.202e-08	64.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4ET92@85013|Frankiales	201174|Actinobacteria	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_7520632_8	1297742.A176_06640	2e-22	107.0	COG1835@1|root,COG1835@2|Bacteria,1REU1@1224|Proteobacteria,431CG@68525|delta/epsilon subdivisions,2WWN0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ZZS2_k127_7520632_12	1166018.FAES_0417	1.698e-06	60.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,47T6F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
ZZS2_k127_7520632_3	709986.Deima_1037	4.336e-91	308.0	COG0330@1|root,COG0330@2|Bacteria,1WIW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_7520632_1	756272.Plabr_1949	3.208e-148	503.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
ZZS2_k127_7520632_4	1287116.X734_13430	6.284e-66	234.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS2_k127_7520632_5	158190.SpiGrapes_1961	6.679e-40	168.0	28PJ3@1|root,2ZC8W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7520632_2	234267.Acid_2430	1.715e-104	353.0	COG4941@1|root,COG4941@2|Bacteria,3Y42G@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
ZZS2_k127_7520632_9	1144275.COCOR_00143	3.398e-17	88.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS2_k127_7520632_0	1415779.JOMH01000001_gene1637	0.0	1102.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,1S05Q@1236|Gammaproteobacteria,1X429@135614|Xanthomonadales	135614|Xanthomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
ZZS2_k127_7520632_15	1487953.JMKF01000056_gene4436	0.000973	53.0	COG0633@1|root,COG0633@2|Bacteria,1G6S2@1117|Cyanobacteria,1HBJR@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
ZZS2_k127_7520632_13	502025.Hoch_0450	5.436e-06	60.0	COG0484@1|root,COG0484@2|Bacteria,1QABU@1224|Proteobacteria,434YT@68525|delta/epsilon subdivisions,2WZ9Q@28221|Deltaproteobacteria,2Z1NF@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7520632_10	1125863.JAFN01000001_gene2826	2.173e-08	68.0	COG3005@1|root,COG3005@2|Bacteria,1QYGG@1224|Proteobacteria,42NFU@68525|delta/epsilon subdivisions,2WKHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
ZZS2_k127_7520632_7	237727.NAP1_09562	2.355e-24	120.0	COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QUPD@1224|Proteobacteria,2TW3N@28211|Alphaproteobacteria,2K28S@204457|Sphingomonadales	204457|Sphingomonadales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_2,Pyr_redox_3,cNMP_binding
ZZS2_k127_7520632_14	1123253.AUBD01000008_gene559	0.0004635	51.0	29W19@1|root,30HJP@2|Bacteria,1R60N@1224|Proteobacteria,1S21W@1236|Gammaproteobacteria,1X6BC@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7520632_11	585198.HMPREF0574_1265	4.452e-08	61.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4D4C8@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
ZZS2_k127_7538333_14	1142394.PSMK_02870	1.974e-13	80.0	2EU5N@1|root,33MN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7538333_13	82654.Pse7367_0062	3.813e-17	96.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
ZZS2_k127_7538333_10	339670.Bamb_1947	6.578e-36	140.0	COG3602@1|root,COG3602@2|Bacteria,1MZKQ@1224|Proteobacteria,2VUWE@28216|Betaproteobacteria,1K95Y@119060|Burkholderiaceae	28216|Betaproteobacteria	S	ACT domain	-	-	-	ko:K09964	-	-	-	-	ko00000	-	-	-	ACT_3,ACT_7
ZZS2_k127_7538333_0	1121920.AUAU01000010_gene72	2.289e-288	897.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS2_k127_7538333_4	663932.KB902575_gene1239	2.202e-85	309.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,2JPEV@204441|Rhodospirillales	204441|Rhodospirillales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
ZZS2_k127_7538333_8	1128421.JAGA01000002_gene1039	8.807e-48	180.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2NR4E@2323|unclassified Bacteria	2|Bacteria	H	MoaE protein	moaD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.7.7.77,2.8.1.12,4.6.1.17	ko:K03635,ko:K03636,ko:K03637,ko:K03752,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372,R11581	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	MoaE,ThiS
ZZS2_k127_7538333_15	760192.Halhy_2705	1.347e-07	64.0	COG0457@1|root,COG0457@2|Bacteria	760192.Halhy_2705|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7538333_5	861299.J421_3106	2.181e-84	300.0	COG0158@1|root,COG0158@2|Bacteria,1ZTAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
ZZS2_k127_7538333_12	378806.STAUR_3209	5.464e-22	113.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS2_k127_7538333_11	1297865.APJD01000022_gene328	1.185e-26	126.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,3JUS4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
ZZS2_k127_7538333_3	69042.WH5701_03034	9.407e-105	363.0	COG0136@1|root,COG0136@2|Bacteria,1G0E6@1117|Cyanobacteria,1GYKG@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS2_k127_7538333_9	1109445.AGSX01000171_gene1041	1.859e-43	169.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1Z22I@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
ZZS2_k127_7538333_7	289376.THEYE_A1481	5.139e-61	238.0	COG0793@1|root,COG0793@2|Bacteria,3J09Y@40117|Nitrospirae	40117|Nitrospirae	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
ZZS2_k127_7538333_6	886293.Sinac_7534	4.131e-67	259.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7538333_1	713587.THITH_03495	4.492e-214	681.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1WX9G@135613|Chromatiales	135613|Chromatiales	C	PFAM Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
ZZS2_k127_7538333_2	234267.Acid_3914	5.549e-115	408.0	COG2010@1|root,COG3386@1|root,COG2010@2|Bacteria,COG3386@2|Bacteria,3Y9A6@57723|Acidobacteria	2|Bacteria	C	PFAM SMP-30 Gluconolaconase	peaA	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	1.4.9.1	ko:K08685,ko:K14274	ko00040,ko00680,ko01120,map00040,map00680,map01120	-	R00606,R02427	RC00189,RC00713	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV,SGL
ZZS2_k127_7551884_5	1394178.AWOO02000003_gene2843	3.76e-10	74.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria,4EH51@85012|Streptosporangiales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
ZZS2_k127_7551884_2	1210884.HG799462_gene8796	3.045e-53	215.0	COG0515@1|root,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	1210884.HG799462_gene8796|-	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7551884_4	243090.RB6034	9.821e-13	77.0	COG1595@1|root,COG1595@2|Bacteria,2J02A@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_7551884_3	575540.Isop_3634	2.296e-28	118.0	COG0824@1|root,COG0824@2|Bacteria,2J0BH@203682|Planctomycetes	203682|Planctomycetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
ZZS2_k127_7551884_0	246197.MXAN_5758	4.067e-144	477.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
ZZS2_k127_7551884_1	177437.HRM2_43250	2.664e-74	273.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG3850@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MHUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
ZZS2_k127_7604037_0	1123508.JH636452_gene7057	0.0	1549.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2J2J0@203682|Planctomycetes	203682|Planctomycetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT,VWA_3
ZZS2_k127_7604037_1	215803.DB30_1894	1.236e-56	220.0	COG2819@1|root,COG2819@2|Bacteria,1R9SG@1224|Proteobacteria,43BHU@68525|delta/epsilon subdivisions,2X4RC@28221|Deltaproteobacteria,2YZFM@29|Myxococcales	28221|Deltaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
ZZS2_k127_7604037_3	530564.Psta_1895	6.405e-06	56.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2J2J0@203682|Planctomycetes	203682|Planctomycetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT,VWA_3
ZZS2_k127_7604037_2	448385.sce2570	7.774e-56	216.0	COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria,2YVNH@29|Myxococcales	28221|Deltaproteobacteria	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
ZZS2_k127_7646696_8	82654.Pse7367_0038	3.37e-49	188.0	COG1989@1|root,COG1989@2|Bacteria,1FZZA@1117|Cyanobacteria,1H7ST@1150|Oscillatoriales	1117|Cyanobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	hofD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
ZZS2_k127_7646696_11	247490.KSU1_B0095	6.011e-26	115.0	COG1360@1|root,COG1360@2|Bacteria,2IZSF@203682|Planctomycetes	203682|Planctomycetes	N	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
ZZS2_k127_7646696_1	247490.KSU1_B0092	1.191e-151	502.0	COG0480@1|root,COG0480@2|Bacteria,2IX5V@203682|Planctomycetes	203682|Planctomycetes	J	COG0480 Translation elongation factors	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS2_k127_7646696_3	443143.GM18_2496	4.882e-121	399.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS2_k127_7646696_2	639282.DEFDS_1109	1.154e-149	492.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS2_k127_7646696_4	497964.CfE428DRAFT_3562	2.541e-94	323.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS2_k127_7646696_14	204669.Acid345_1569	2.006e-07	64.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_7646696_15	204669.Acid345_1569	2.641e-07	61.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS2_k127_7646696_5	743720.Psefu_3788	5.864e-81	283.0	COG0463@1|root,COG0463@2|Bacteria,1PGTA@1224|Proteobacteria,1SWND@1236|Gammaproteobacteria,1YZE8@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_7646696_10	1342301.JASD01000008_gene678	1.724e-29	136.0	COG0438@1|root,COG0438@2|Bacteria,1RCNE@1224|Proteobacteria,2U7UM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
ZZS2_k127_7646696_12	234267.Acid_6770	2.271e-25	124.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,3Y77J@57723|Acidobacteria	57723|Acidobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_11,TPR_16
ZZS2_k127_7646696_6	1304875.JAFZ01000002_gene168	7.452e-53	208.0	COG0084@1|root,COG0084@2|Bacteria,3TAUA@508458|Synergistetes	508458|Synergistetes	L	Hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ZZS2_k127_7646696_13	31964.CMS2128	3.985e-10	72.0	COG4912@1|root,COG4912@2|Bacteria,2GPHE@201174|Actinobacteria,4FPTA@85023|Microbacteriaceae	201174|Actinobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
ZZS2_k127_7646696_0	502025.Hoch_5286	8.435e-199	628.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWSI@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
ZZS2_k127_7646696_7	251221.35211228	6.202e-52	208.0	COG0521@1|root,COG0521@2|Bacteria,1G514@1117|Cyanobacteria	1117|Cyanobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
ZZS2_k127_7646696_9	76114.ebA2758	4.15e-32	130.0	294JI@1|root,2ZRZ3@2|Bacteria,1REGD@1224|Proteobacteria,2VRDG@28216|Betaproteobacteria,2KYGP@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4863
ZZS2_k127_7646696_16	1122603.ATVI01000007_gene1509	0.0003949	52.0	COG4932@1|root,COG5276@1|root,COG4932@2|Bacteria,COG5276@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
ZZS2_k127_765283_4	1128421.JAGA01000001_gene2328	6.848e-08	65.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_765283_5	926564.KI911725_gene2051	8.013e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_765283_2	644282.Deba_3075	1.517e-22	110.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS2_k127_765283_1	1125973.JNLC01000010_gene1345	2.847e-41	175.0	2DBM1@1|root,2Z9WN@2|Bacteria,1RDCQ@1224|Proteobacteria,2UMV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_765283_3	216594.MMAR_2307	5.485e-10	73.0	COG1269@1|root,COG1269@2|Bacteria,2I964@201174|Actinobacteria,238CA@1762|Mycobacteriaceae	201174|Actinobacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_765283_0	344747.PM8797T_25351	2.33e-97	335.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
ZZS2_k127_7709960_6	561175.KB894093_gene3077	2.972e-05	58.0	COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria,4EHT9@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
ZZS2_k127_7709960_5	160799.PBOR_29855	8.318e-07	63.0	COG1470@1|root,COG5434@1|root,COG5520@1|root,COG1470@2|Bacteria,COG5434@2|Bacteria,COG5520@2|Bacteria,1VC96@1239|Firmicutes,4HV2Q@91061|Bacilli,2774T@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Big_4,CBM9_1,Pectate_lyase_3,SLH
ZZS2_k127_7709960_1	246194.CHY_1758	3.533e-193	648.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,42F53@68295|Thermoanaerobacterales	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ZZS2_k127_7709960_3	596151.DesfrDRAFT_2988	7.746e-23	100.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MCE1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
ZZS2_k127_7709960_4	1396141.BATP01000039_gene1364	1.307e-17	94.0	COG2143@1|root,COG2143@2|Bacteria,46Z6E@74201|Verrucomicrobia,2IW7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
ZZS2_k127_7709960_2	491915.Aflv_2555	3.562e-146	481.0	COG2865@1|root,COG2865@2|Bacteria,1TT5X@1239|Firmicutes,4HS3N@91061|Bacilli	91061|Bacilli	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
ZZS2_k127_7709960_0	1123023.JIAI01000009_gene1065	2.518e-274	861.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4DX9G@85010|Pseudonocardiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
ZZS2_k127_7729574_10	641526.ADIWIN_0001	1.09e-06	53.0	COG2890@1|root,COG2890@2|Bacteria,4NHRN@976|Bacteroidetes,1HZB9@117743|Flavobacteriia	976|Bacteroidetes	J	COG2890 Methylase of polypeptide chain release factors	-	-	-	-	-	-	-	-	-	-	-	-	MTS,PrmA
ZZS2_k127_7729574_1	861299.J421_1935	5.932e-204	659.0	COG2091@1|root,COG2091@2|Bacteria,1ZU9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7729574_6	1121377.KB906405_gene108	4.643e-15	82.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS2_k127_7729574_0	1121920.AUAU01000004_gene739	2.135e-237	746.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
ZZS2_k127_7729574_8	204669.Acid345_1037	1.284e-09	70.0	COG3595@1|root,COG3595@2|Bacteria,3Y97I@57723|Acidobacteria,2JNRB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7729574_9	1232410.KI421424_gene1769	6.364e-09	66.0	COG3637@1|root,COG3637@2|Bacteria,1RG1M@1224|Proteobacteria,42VR0@68525|delta/epsilon subdivisions,2WS4Z@28221|Deltaproteobacteria,43USG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7729574_7	1211579.PP4_19800	1.673e-10	72.0	COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,1YXN5@136845|Pseudomonas putida group	1236|Gammaproteobacteria	MP	PFAM OmpA MotB domain protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	OmpA,PBP_like_2
ZZS2_k127_7729574_4	479434.Sthe_2225	2.53e-79	285.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi,27Y0D@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
ZZS2_k127_7729574_2	1303518.CCALI_02632	1.281e-113	402.0	COG0214@1|root,COG0214@2|Bacteria	2|Bacteria	H	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
ZZS2_k127_7729574_5	682795.AciX8_1360	4.482e-46	174.0	COG0311@1|root,COG0311@2|Bacteria,3Y4GN@57723|Acidobacteria,2JJ3V@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
ZZS2_k127_7729574_3	357808.RoseRS_3163	3.738e-84	291.0	COG3804@1|root,COG3804@2|Bacteria,2G7MJ@200795|Chloroflexi	200795|Chloroflexi	C	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
ZZS2_k127_7744396_1	794903.OPIT5_22910	8.774e-25	121.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS2_k127_7744396_0	215803.DB30_6945	1.337e-78	286.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria,2YUQR@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
ZZS2_k127_7793085_11	55952.BU52_12880	4.978e-20	102.0	COG0726@1|root,COG3055@1|root,COG0726@2|Bacteria,COG3055@2|Bacteria,2GK14@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,PA14
ZZS2_k127_7793085_14	1121481.AUAS01000006_gene877	8.077e-12	78.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
ZZS2_k127_7793085_12	448385.sce8271	1.782e-17	98.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
ZZS2_k127_7793085_16	356851.JOAN01000010_gene4654	6.111e-07	61.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4DB81@85008|Micromonosporales	201174|Actinobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS2_k127_7793085_3	1122915.AUGY01000083_gene4486	6.308e-88	299.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,26RVU@186822|Paenibacillaceae	91061|Bacilli	S	magnesium chelatase	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS2_k127_7793085_2	1487953.JMKF01000048_gene2036	3.644e-119	398.0	COG1834@1|root,COG1915@1|root,COG1834@2|Bacteria,COG1915@2|Bacteria,1G2AU@1117|Cyanobacteria,1H7S0@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
ZZS2_k127_7793085_13	1254432.SCE1572_30225	2.576e-17	93.0	COG0515@1|root,COG1672@1|root,COG2319@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,4328Z@68525|delta/epsilon subdivisions,2X7NM@28221|Deltaproteobacteria,2YXMY@29|Myxococcales	28221|Deltaproteobacteria	T	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Pkinase,WD40
ZZS2_k127_7793085_6	404589.Anae109_3408	2.115e-46	189.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
ZZS2_k127_7793085_15	357808.RoseRS_4116	1.335e-09	70.0	COG2340@1|root,COG2340@2|Bacteria,2GAE7@200795|Chloroflexi,375RA@32061|Chloroflexia	32061|Chloroflexia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
ZZS2_k127_7793085_9	358681.BBR47_45580	1.577e-23	119.0	COG4932@1|root,COG4932@2|Bacteria,1UJQY@1239|Firmicutes,4ITDJ@91061|Bacilli,270X3@186822|Paenibacillaceae	91061|Bacilli	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_7793085_4	479433.Caci_0748	9.482e-72	252.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7793085_0	204669.Acid345_1384	7.691e-294	916.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS2_k127_7793085_1	1267533.KB906735_gene4586	2.863e-122	396.0	COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
ZZS2_k127_7793085_7	1267534.KB906759_gene1794	1.103e-40	156.0	2EDAV@1|root,33776@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7793085_10	379066.GAU_0679	1.077e-22	114.0	COG3342@1|root,COG3342@2|Bacteria,1ZUFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
ZZS2_k127_7793085_17	1133850.SHJG_1542	3.267e-05	57.0	COG3468@1|root,COG3468@2|Bacteria,2H6JR@201174|Actinobacteria	201174|Actinobacteria	MU	Cell surface	-	-	-	-	-	-	-	-	-	-	-	-	TIG
ZZS2_k127_7793085_8	67267.JNXT01000011_gene1051	1.348e-32	147.0	COG0827@1|root,COG0827@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Methyltransf_31,N6_Mtase,TaqI_C
ZZS2_k127_7793085_5	1121957.ATVL01000014_gene1459	1.576e-53	205.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7810370_0	575540.Isop_2326	2.851e-97	344.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_7810370_1	530564.Psta_4732	8.925e-78	268.0	COG1136@1|root,COG1136@2|Bacteria,2IY81@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_7810370_2	1232437.KL662020_gene700	1.135e-56	223.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS2_k127_7810370_3	1131269.AQVV01000053_gene213	1.343e-18	97.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,OEP
ZZS2_k127_7813183_3	945713.IALB_2695	2.293e-53	196.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_2695|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7813183_5	234267.Acid_4321	2.249e-31	141.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS2_k127_7813183_4	1469607.KK073769_gene6106	1.372e-35	139.0	COG2337@1|root,COG2337@2|Bacteria,1G7P3@1117|Cyanobacteria,1HPNZ@1161|Nostocales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
ZZS2_k127_7813183_7	671143.DAMO_1478	1.168e-20	93.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	RHH_1
ZZS2_k127_7813183_0	1384056.N787_09570	9.81e-299	930.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
ZZS2_k127_7813183_2	867903.ThesuDRAFT_02308	1.092e-71	259.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WCG8@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
ZZS2_k127_7813183_6	106370.Francci3_2880	3.318e-31	130.0	COG5464@1|root,COG5464@2|Bacteria,2II2Z@201174|Actinobacteria	201174|Actinobacteria	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
ZZS2_k127_7813183_9	1437824.BN940_00086	9.387e-05	55.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,2VPG3@28216|Betaproteobacteria,3T7GV@506|Alcaligenaceae	28216|Betaproteobacteria	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_7813183_1	234267.Acid_3165	2.785e-82	289.0	COG2812@1|root,COG2812@2|Bacteria,3Y3C4@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
ZZS2_k127_7827850_5	1192034.CAP_5364	2.109e-05	59.0	COG4932@1|root,COG4932@2|Bacteria,1PF83@1224|Proteobacteria,430QE@68525|delta/epsilon subdivisions,2WVYF@28221|Deltaproteobacteria,2Z1TZ@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_7827850_2	522306.CAP2UW1_0409	1.456e-107	364.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,1KPRM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
ZZS2_k127_7827850_1	398767.Glov_2688	3.375e-149	488.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
ZZS2_k127_7827850_0	525146.Ddes_1626	6.474e-218	703.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2M832@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
ZZS2_k127_7827850_3	1449976.KALB_1275	3.13e-97	329.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4DZ4D@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6
ZZS2_k127_7827850_4	1095769.CAHF01000006_gene1915	2.272e-14	77.0	COG1977@1|root,COG1977@2|Bacteria,1PT86@1224|Proteobacteria,2VYZI@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7837337_12	1210884.HG799471_gene14633	2.05e-94	323.0	COG2010@1|root,COG2010@2|Bacteria,2IXIG@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_7837337_17	1123504.JQKD01000005_gene4749	6.75e-78	278.0	COG4948@1|root,COG4948@2|Bacteria,1MV2S@1224|Proteobacteria,2VPM7@28216|Betaproteobacteria,4AGFV@80864|Comamonadaceae	28216|Betaproteobacteria	M	Enolase C-terminal domain-like	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
ZZS2_k127_7837337_6	530564.Psta_0761	6.791e-138	454.0	COG1902@1|root,COG1902@2|Bacteria,2IXBM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
ZZS2_k127_7837337_23	644283.Micau_3039	9.539e-56	222.0	COG0329@1|root,COG0329@2|Bacteria,2GJEU@201174|Actinobacteria,4DBAQ@85008|Micromonosporales	201174|Actinobacteria	EM	Protein of unknown function (DUF993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF993
ZZS2_k127_7837337_18	1458357.BG58_19125	2.143e-74	262.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,1K5U4@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS2_k127_7837337_34	1254432.SCE1572_13185	1.693e-05	57.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_7837337_33	388467.A19Y_2252	2.14e-06	61.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G3QU@1117|Cyanobacteria,1HAPS@1150|Oscillatoriales	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PPC,Peptidase_C11
ZZS2_k127_7837337_15	452637.Oter_4001	5.971e-84	315.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
ZZS2_k127_7837337_8	929558.SMGD1_0478	1.146e-109	364.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2YMSE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
ZZS2_k127_7837337_9	383372.Rcas_0203	1.566e-105	354.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi,375A6@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS2_k127_7837337_11	443144.GM21_0941	3.475e-100	352.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS2_k127_7837337_24	929558.SMGD1_0476	7.174e-55	202.0	COG2227@1|root,COG2227@2|Bacteria,1QTWG@1224|Proteobacteria	1224|Proteobacteria	H	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_12,Methyltransf_23
ZZS2_k127_7837337_4	1123508.JH636448_gene7633	2.467e-169	551.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
ZZS2_k127_7837337_3	886293.Sinac_2223	2.763e-190	629.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
ZZS2_k127_7837337_32	76114.ebA4944	4.075e-07	55.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,2KVCU@206389|Rhodocyclales	206389|Rhodocyclales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
ZZS2_k127_7837337_16	96561.Dole_3137	5.46e-79	278.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
ZZS2_k127_7837337_26	314278.NB231_07287	1.983e-51	188.0	COG4976@1|root,COG4976@2|Bacteria,1QYTJ@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
ZZS2_k127_7837337_19	909663.KI867150_gene1728	3.373e-72	260.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,42W8F@68525|delta/epsilon subdivisions,2WRG3@28221|Deltaproteobacteria,2MS12@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
ZZS2_k127_7837337_20	234267.Acid_6301	8.154e-65	233.0	COG2227@1|root,COG2227@2|Bacteria,3Y8XU@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ZZS2_k127_7837337_13	616991.JPOO01000001_gene4186	1.475e-93	333.0	COG0451@1|root,COG0451@2|Bacteria,4NXEA@976|Bacteroidetes,1I65H@117743|Flavobacteriia,23G3R@178469|Arenibacter	976|Bacteroidetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS2_k127_7837337_10	1121875.KB907546_gene2707	2.331e-105	354.0	COG1063@1|root,COG1063@2|Bacteria,4NJ3P@976|Bacteroidetes,1HZTH@117743|Flavobacteriia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS2_k127_7837337_2	886293.Sinac_5697	1.045e-194	612.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_7837337_5	344747.PM8797T_17402	4.063e-164	525.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_7837337_22	1382306.JNIM01000001_gene1022	2.993e-62	219.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
ZZS2_k127_7837337_0	1382306.JNIM01000001_gene1023	4.684e-273	865.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS2_k127_7837337_14	485913.Krac_2435	1.934e-93	317.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
ZZS2_k127_7837337_25	1192034.CAP_8404	4.118e-53	208.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
ZZS2_k127_7837337_30	1205680.CAKO01000029_gene5118	7.378e-36	141.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,2UEJ2@28211|Alphaproteobacteria,2JY7U@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
ZZS2_k127_7837337_21	926569.ANT_14920	2.031e-64	229.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
ZZS2_k127_7837337_27	537972.ABQU01000032_gene1581	3.222e-45	176.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2YNVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	bacterioferritin comigratory protein	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS2_k127_7837337_28	370438.PTH_1951	2.387e-41	169.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,261RV@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
ZZS2_k127_7837337_7	309801.trd_0432	9.206e-132	434.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,27XS9@189775|Thermomicrobia	189775|Thermomicrobia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
ZZS2_k127_7837337_29	404589.Anae109_4140	3.657e-40	163.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS2_k127_7837337_1	404380.Gbem_4007	3.661e-211	678.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QGH@68525|delta/epsilon subdivisions,2WKTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type 2	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
ZZS2_k127_7837337_31	1239962.C943_03325	4.412e-08	62.0	2DPN8@1|root,332RD@2|Bacteria,4NX8C@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7840222_10	1124780.ANNU01000028_gene955	8.408e-44	176.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
ZZS2_k127_7840222_11	1158292.JPOE01000005_gene815	1.357e-42	175.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,2VTMV@28216|Betaproteobacteria,1KNC3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_7840222_14	263358.VAB18032_05985	6.252e-38	166.0	COG2866@1|root,COG2866@2|Bacteria,2GN49@201174|Actinobacteria,4DAA1@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase M14, carboxypeptidase A	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
ZZS2_k127_7840222_8	1235798.C817_01656	1.074e-44	180.0	COG0438@1|root,COG0438@2|Bacteria,1TYQV@1239|Firmicutes,259DE@186801|Clostridia,27VXI@189330|Dorea	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS2_k127_7840222_1	1121861.KB899911_gene1186	1.006e-179	615.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales	28211|Alphaproteobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ZZS2_k127_7840222_6	1123355.JHYO01000031_gene1566	4.196e-56	214.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7840222_17	1434929.X946_2897	0.0003365	45.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2VK05@28216|Betaproteobacteria,1K33H@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
ZZS2_k127_7840222_15	344747.PM8797T_00397	1.537e-12	75.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
ZZS2_k127_7840222_12	2002.JOEQ01000038_gene4205	3.032e-41	169.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	ubiG	-	2.1.1.265,2.1.1.294,2.7.1.181	ko:K15257,ko:K16868,ko:K18827,ko:K20444	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005,ko02000,ko03016	4.D.1.3	GT2,GT4	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
ZZS2_k127_7840222_9	755178.Cyan10605_1081	1.088e-44	173.0	COG0500@1|root,COG2226@2|Bacteria,1GAPB@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS2_k127_7840222_7	1123060.JONP01000010_gene2187	2.027e-53	215.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2V85C@28211|Alphaproteobacteria,2JUG7@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_7840222_16	1121861.KB899911_gene1187	2.437e-10	74.0	COG2264@1|root,COG2264@2|Bacteria,1RCZ3@1224|Proteobacteria,2TZKH@28211|Alphaproteobacteria,2JYC6@204441|Rhodospirillales	1224|Proteobacteria	J	Protein of unknown function (DUF1698)	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,PrmA
ZZS2_k127_7840222_5	555079.Toce_0489	6.471e-67	249.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,42FMM@68295|Thermoanaerobacterales	186801|Clostridia	GM	ABC transporter related	-	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran,Wzt_C
ZZS2_k127_7840222_13	234267.Acid_0555	3.4e-40	159.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
ZZS2_k127_7840222_0	443598.AUFA01000032_gene6444	2.548e-211	683.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3JUS1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
ZZS2_k127_7840222_4	1120983.KB894574_gene784	7.985e-90	315.0	COG1231@1|root,COG1231@2|Bacteria,1Q2M3@1224|Proteobacteria,2TT8M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
ZZS2_k127_7840222_3	240016.ABIZ01000001_gene872	2.808e-115	383.0	2BQYI@1|root,32JVT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7840222_2	518766.Rmar_0395	7.359e-177	576.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1FIJ4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS2_k127_792928_0	379066.GAU_2208	4.432e-164	521.0	COG0451@1|root,COG0451@2|Bacteria,1ZUAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
ZZS2_k127_792928_6	740709.A10D4_00975	1.059e-15	92.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
ZZS2_k127_792928_4	1121015.N789_09700	9.582e-42	177.0	COG5397@1|root,COG5397@2|Bacteria,1PJM3@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
ZZS2_k127_792928_5	448385.sce9049	3.849e-34	147.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
ZZS2_k127_792928_1	1174528.JH992887_gene6180	2.742e-107	371.0	COG1680@1|root,COG1680@2|Bacteria,1G5Z2@1117|Cyanobacteria,1JK0D@1189|Stigonemataceae	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_792928_2	1411123.JQNH01000001_gene137	7.788e-96	323.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2TRRV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG2513 PEP phosphonomutase and related enzymes	MA20_35565	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
ZZS2_k127_792928_3	1123242.JH636436_gene501	1.183e-81	288.0	COG0330@1|root,COG0330@2|Bacteria,2IY12@203682|Planctomycetes	203682|Planctomycetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS2_k127_7953234_4	378806.STAUR_0399	1.181e-20	100.0	COG0517@1|root,COG0517@2|Bacteria,1N9X9@1224|Proteobacteria,4375S@68525|delta/epsilon subdivisions,2X9SS@28221|Deltaproteobacteria,2YXN7@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS2_k127_7953234_1	1128421.JAGA01000002_gene1840	1.704e-47	189.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22,MFS_1
ZZS2_k127_7953234_3	861299.J421_2586	1.575e-24	117.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
ZZS2_k127_7953234_0	1454004.AW11_02489	2.007e-94	321.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2VTJU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
ZZS2_k127_7953234_2	1454004.AW11_02488	1.23e-33	135.0	COG0394@1|root,COG0704@1|root,COG0394@2|Bacteria,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	1.20.4.1,3.1.3.48	ko:K01104,ko:K02039,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	PhoU
ZZS2_k127_7962570_0	1123053.AUDG01000014_gene2088	1.828e-223	705.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WYHW@135613|Chromatiales	135613|Chromatiales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS2_k127_7962570_9	335543.Sfum_1407	4.386e-21	99.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,42TZ7@68525|delta/epsilon subdivisions,2WR0Y@28221|Deltaproteobacteria,2MS1K@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
ZZS2_k127_7962570_13	1121439.dsat_2621	1.653e-09	64.0	COG4118@1|root,COG4118@2|Bacteria,1Q43S@1224|Proteobacteria,42VPT@68525|delta/epsilon subdivisions,2WS3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
ZZS2_k127_7962570_2	1121472.AQWN01000007_gene1144	2.558e-115	390.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
ZZS2_k127_7962570_10	1163407.UU7_03747	4.376e-19	95.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_7962570_1	56110.Oscil6304_5018	2.917e-123	428.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
ZZS2_k127_7962570_15	1410631.JHWZ01000002_gene1312	6.431e-06	57.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia,27MRQ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
ZZS2_k127_7962570_8	526227.Mesil_3115	2.323e-36	158.0	COG2199@1|root,COG3706@2|Bacteria,1WIYY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ZZS2_k127_7962570_7	756272.Plabr_1325	7.225e-42	172.0	COG1253@1|root,COG1253@2|Bacteria,2IZAU@203682|Planctomycetes	203682|Planctomycetes	S	COG1253 Hemolysins and related	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
ZZS2_k127_7962570_12	595460.RRSWK_05876	3.117e-10	74.0	COG1381@1|root,COG1381@2|Bacteria,2IZU9@203682|Planctomycetes	203682|Planctomycetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
ZZS2_k127_7962570_16	237368.SCABRO_01972	0.0004723	52.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,YfiO
ZZS2_k127_7962570_14	1142394.PSMK_25100	2.063e-06	60.0	COG2980@1|root,COG2980@2|Bacteria,2J0MT@203682|Planctomycetes	203682|Planctomycetes	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
ZZS2_k127_7962570_5	87626.PTD2_11689	4.459e-55	203.0	COG0652@1|root,COG0652@2|Bacteria,1RBX1@1224|Proteobacteria,1SYJW@1236|Gammaproteobacteria,2Q28R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS2_k127_7962570_11	768710.DesyoDRAFT_0348	4.678e-19	100.0	COG4641@1|root,COG4641@2|Bacteria,1V2W1@1239|Firmicutes,24GPM@186801|Clostridia,262M0@186807|Peptococcaceae	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ZZS2_k127_7962570_6	237368.SCABRO_03057	2.94e-44	181.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
ZZS2_k127_7962570_4	1385515.N791_03730	1.673e-60	219.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1X51A@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_7962570_3	404589.Anae109_2716	1.134e-67	243.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
ZZS2_k127_7973811_3	530564.Psta_3753	8.017e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_7973811_5	120017.I2G1U6	0.0001135	55.0	2D3YI@1|root,2S51F@2759|Eukaryota,3A690@33154|Opisthokonta,3P6A4@4751|Fungi,3V1M2@5204|Basidiomycota,3N27G@452284|Ustilaginomycotina	4751|Fungi	S	F-box-like	-	-	-	-	-	-	-	-	-	-	-	-	F-box-like
ZZS2_k127_7973811_1	1267533.KB906737_gene1750	3.147e-104	363.0	COG0457@1|root,COG0457@2|Bacteria,3Y67F@57723|Acidobacteria,2JMD4@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_7973811_2	1112217.PPL19_01040	1.136e-32	146.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2206 HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
ZZS2_k127_7973811_0	1382304.JNIL01000001_gene2697	4.793e-134	451.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,2798F@186823|Alicyclobacillaceae	91061|Bacilli	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ZZS2_k127_7973811_4	1499967.BAYZ01000170_gene5527	2.501e-14	84.0	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DUF4062,FGE-sulfatase,NACHT,TIR_2,TPR_12
ZZS2_k127_7973811_6	550540.Fbal_2006	0.0006595	53.0	2BU8D@1|root,32PHV@2|Bacteria,1NANB@1224|Proteobacteria,1SFYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
ZZS2_k127_7982803_8	749222.Nitsa_0031	0.0001698	50.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
ZZS2_k127_7982803_4	521674.Plim_0245	7.609e-54	205.0	COG0585@1|root,COG0585@2|Bacteria,2IYMT@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
ZZS2_k127_7982803_2	1158318.ATXC01000001_gene1288	6.857e-82	282.0	COG0777@1|root,COG0777@2|Bacteria,2G3MC@200783|Aquificae	200783|Aquificae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
ZZS2_k127_7982803_3	452637.Oter_4448	2.09e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,46TEK@74201|Verrucomicrobia,3K7FI@414999|Opitutae	2|Bacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ZZS2_k127_7982803_0	1232683.ADIMK_0125	2.128e-161	527.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0405 Gamma-glutamyltransferase	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706	G_glu_transpept
ZZS2_k127_7982803_5	573.JG24_22690	3.133e-18	88.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease containing a URI domain	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
ZZS2_k127_7982803_1	1123257.AUFV01000021_gene2018	4.427e-136	443.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
ZZS2_k127_7982803_6	1121899.Q764_08835	1.689e-10	74.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,2NU2K@237|Flavobacterium	976|Bacteroidetes	S	BatD protein	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
ZZS2_k127_7984926_2	1089553.Tph_c02290	3.713e-24	115.0	COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,25EAY@186801|Clostridia,42G5D@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS2_k127_7984926_1	1121033.AUCF01000001_gene2521	6.323e-157	521.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TS79@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
ZZS2_k127_7984926_0	521674.Plim_2372	0.0	1174.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	atsB	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
ZZS2_k127_8029840_4	530564.Psta_4732	8.83e-59	224.0	COG1136@1|root,COG1136@2|Bacteria,2IY81@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_8029840_3	886293.Sinac_4798	1.531e-93	328.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS2_k127_8029840_5	886293.Sinac_4800	3.738e-57	223.0	COG0845@1|root,COG0845@2|Bacteria,2IXP7@203682|Planctomycetes	203682|Planctomycetes	M	COG0845 Membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
ZZS2_k127_8029840_2	395493.BegalDRAFT_3543	8.045e-100	345.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,461W5@72273|Thiotrichales	72273|Thiotrichales	I	3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase)	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
ZZS2_k127_8029840_1	395493.BegalDRAFT_3543	3.505e-105	362.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,1RQXH@1236|Gammaproteobacteria,461W5@72273|Thiotrichales	72273|Thiotrichales	I	3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase)	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
ZZS2_k127_8029840_6	1408433.JHXV01000008_gene120	1.592e-48	185.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,2PBKP@246874|Cryomorphaceae	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
ZZS2_k127_8029840_7	1504981.KO116_3681	2.318e-45	171.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RQTW@1236|Gammaproteobacteria,1XR9G@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
ZZS2_k127_8029840_0	1123073.KB899241_gene3430	3.062e-118	412.0	COG1506@1|root,COG1506@2|Bacteria,1N75C@1224|Proteobacteria,1RXY1@1236|Gammaproteobacteria,1X51F@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS2_k127_8029840_8	290397.Adeh_0237	5.322e-10	74.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core
ZZS2_k127_8058164_2	1173028.ANKO01000220_gene584	7.92e-19	102.0	COG1556@1|root,COG1556@2|Bacteria	2|Bacteria	S	LUD domain	lldG	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
ZZS2_k127_8058164_0	469371.Tbis_3244	1.5e-121	421.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4DZA8@85010|Pseudonocardiales	201174|Actinobacteria	C	(4Fe-4S) cluster-containing protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
ZZS2_k127_8058164_1	1411123.JQNH01000001_gene462	1.197e-61	234.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	glycolate oxidase iron-sulfur subunit	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
ZZS2_k127_8058164_3	1463855.JOHV01000006_gene4928	2.207e-09	68.0	COG0673@1|root,COG0673@2|Bacteria,2GM7J@201174|Actinobacteria	201174|Actinobacteria	K	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS2_k127_8135562_4	983917.RGE_04240	8.964e-48	192.0	COG3307@1|root,COG3307@2|Bacteria,1PH1D@1224|Proteobacteria,2VY0G@28216|Betaproteobacteria,1KMV2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS2_k127_8135562_11	765913.ThidrDRAFT_2782	6.478e-06	59.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,1WW0M@135613|Chromatiales	135613|Chromatiales	M	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
ZZS2_k127_8135562_10	339670.Bamb_5549	1.337e-06	61.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VPSB@28216|Betaproteobacteria,1K0FM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS2_k127_8135562_0	215803.DB30_4886	0.0	1216.0	COG1429@1|root,COG1429@2|Bacteria,1QX7D@1224|Proteobacteria,43C0E@68525|delta/epsilon subdivisions,2X7B3@28221|Deltaproteobacteria,2Z3EW@29|Myxococcales	28221|Deltaproteobacteria	H	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
ZZS2_k127_8135562_5	1120972.AUMH01000011_gene249	1.552e-38	156.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,4HG9Z@91061|Bacilli	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_8135562_9	1030157.AFMP01000019_gene582	2.018e-07	65.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,2U89X@28211|Alphaproteobacteria,2K4XM@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_8135562_12	1144275.COCOR_01518	3.762e-05	58.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_8135562_8	381666.H16_B1662	1.025e-07	63.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VJ3A@28216|Betaproteobacteria,1KH0W@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
ZZS2_k127_8135562_7	448385.sce1556	1.009e-07	65.0	2EYGF@1|root,33RQC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8135562_2	344747.PM8797T_16303	2.117e-54	198.0	COG0229@1|root,COG0229@2|Bacteria,2IZ8D@203682|Planctomycetes	203682|Planctomycetes	C	peptide-methionine (R)-S-oxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
ZZS2_k127_8135562_3	448385.sce8068	1.04e-49	192.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria,2YV8F@29|Myxococcales	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_8135562_1	179408.Osc7112_4904	1.269e-80	282.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
ZZS2_k127_8135562_6	566466.NOR53_2364	2.14e-09	66.0	2B107@1|root,31TVF@2|Bacteria,1QRP2@1224|Proteobacteria,1SP4P@1236|Gammaproteobacteria,1JA9A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Zc3h12a-like Ribonuclease NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	RNase_Zc3h12a
ZZS2_k127_8178314_0	1192034.CAP_3369	6.839e-61	220.0	COG0035@1|root,COG0035@2|Bacteria,1RBD6@1224|Proteobacteria,42R1E@68525|delta/epsilon subdivisions,2WN3Q@28221|Deltaproteobacteria,2YU4E@29|Myxococcales	28221|Deltaproteobacteria	F	Uracil phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UPRTase
ZZS2_k127_8178314_2	1242864.D187_006633	8.697e-30	136.0	COG2333@1|root,COG4733@1|root,COG4932@1|root,COG2333@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.4	ko:K01179,ko:K02238,ko:K20276	ko00500,ko01100,ko02024,map00500,map01100,map02024	M00429	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.11.1,3.A.11.2	GH5,GH9	-	Lactamase_B
ZZS2_k127_8178314_4	1089550.ATTH01000002_gene30	6.004e-05	56.0	COG1404@1|root,COG2356@1|root,COG4412@1|root,COG1404@2|Bacteria,COG2356@2|Bacteria,COG4412@2|Bacteria,4NRFN@976|Bacteroidetes	976|Bacteroidetes	O	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
ZZS2_k127_8178314_1	1256908.HMPREF0373_02717	1.718e-32	146.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25WMX@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
ZZS2_k127_8178314_5	1142394.PSMK_09770	0.0003891	51.0	COG2165@1|root,COG2165@2|Bacteria,2IYB7@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
ZZS2_k127_8178314_3	570967.JMLV01000002_gene1532	1.433e-05	52.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
ZZS2_k127_8189176_22	448385.sce1844	2.474e-12	81.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
ZZS2_k127_8189176_6	1123242.JH636435_gene1124	1.037e-72	270.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	CBM9_1
ZZS2_k127_8189176_23	1380356.JNIK01000011_gene1820	3.18e-11	75.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4ESQ9@85013|Frankiales	201174|Actinobacteria	S	Methyltransferase small domain	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
ZZS2_k127_8189176_13	1162668.LFE_0824	2.467e-41	177.0	COG1858@1|root,COG1858@2|Bacteria,3J0GH@40117|Nitrospirae	40117|Nitrospirae	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
ZZS2_k127_8189176_28	391625.PPSIR1_20349	2.213e-05	59.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PDZ_2
ZZS2_k127_8189176_16	326423.RBAM_035550	2.308e-30	133.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1ZFNE@1386|Bacillus	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU38290	TMP-TENI
ZZS2_k127_8189176_3	867903.ThesuDRAFT_01678	1.125e-102	344.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
ZZS2_k127_8189176_24	1280954.HPO_16975	2.078e-10	74.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,43X3G@69657|Hyphomonadaceae	28211|Alphaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
ZZS2_k127_8189176_18	443152.MDG893_18844	2.12e-25	120.0	COG3014@1|root,COG3014@2|Bacteria,1RA9U@1224|Proteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8189176_19	1211114.ALIP01000029_gene2581	7.587e-17	88.0	COG3417@1|root,COG3417@2|Bacteria,1RAWS@1224|Proteobacteria,1T86D@1236|Gammaproteobacteria,1XA7H@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	LpoB
ZZS2_k127_8189176_8	290397.Adeh_3051	1.266e-53	211.0	COG1216@1|root,COG1216@2|Bacteria,1QW1K@1224|Proteobacteria,43BRI@68525|delta/epsilon subdivisions,2WN0V@28221|Deltaproteobacteria,2Z30Y@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_8189176_21	1131269.AQVV01000013_gene1732	1.212e-14	84.0	COG2456@1|root,COG2456@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	XK27_09090	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
ZZS2_k127_8189176_15	1121904.ARBP01000002_gene6681	5.581e-32	130.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
ZZS2_k127_8189176_10	556268.OFAG_00152	2.318e-49	181.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,472X2@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
ZZS2_k127_8189176_26	877421.AUJT01000014_gene2906	9.947e-07	63.0	COG1705@1|root,COG1705@2|Bacteria,1W1FD@1239|Firmicutes,253E2@186801|Clostridia,27KVP@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
ZZS2_k127_8189176_12	1144932.ATTF01000021_gene23	2.775e-43	174.0	COG5036@1|root,COG5036@2|Bacteria,1RG06@1224|Proteobacteria	1224|Proteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
ZZS2_k127_8189176_11	1144932.ATTF01000017_gene1171	2.941e-45	182.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
ZZS2_k127_8189176_7	66377.JOBH01000005_gene2634	1.068e-62	222.0	COG1309@1|root,COG1309@2|Bacteria,2GJES@201174|Actinobacteria	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS2_k127_8189176_20	68194.JNXR01000007_gene4221	1.002e-16	90.0	COG3011@1|root,COG3011@2|Bacteria,2IFGY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
ZZS2_k127_8189176_14	497964.CfE428DRAFT_2363	2.38e-37	150.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8189176_25	716928.AJQT01000080_gene2260	3.365e-08	66.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,2U1VS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS2_k127_8189176_9	163908.KB235896_gene2298	6.921e-50	199.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
ZZS2_k127_8189176_0	861299.J421_6087	7.1e-236	746.0	COG2936@1|root,COG2936@2|Bacteria,1ZTD6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
ZZS2_k127_8189176_27	1121889.AUDM01000008_gene766	2.782e-06	60.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
ZZS2_k127_8189176_17	1184267.A11Q_2436	1.785e-27	122.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,42QRB@68525|delta/epsilon subdivisions,2MSX5@213481|Bdellovibrionales,2WMSD@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
ZZS2_k127_8189176_4	243090.RB6151	2.098e-79	275.0	COG3361@1|root,COG3361@2|Bacteria,2IYZC@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
ZZS2_k127_8189176_2	1038869.AXAN01000051_gene5560	1.895e-153	517.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,1K180@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	ttuE	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
ZZS2_k127_8189176_5	575540.Isop_1099	8.74e-78	273.0	COG0845@1|root,COG0845@2|Bacteria,2J330@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
ZZS2_k127_8189176_1	1121406.JAEX01000011_gene2018	6.027e-209	716.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MA4J@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS2_k127_822610_9	96561.Dole_2043	2.596e-23	115.0	COG1800@1|root,COG2885@1|root,COG3420@1|root,COG1800@2|Bacteria,COG2885@2|Bacteria,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_822610_13	1227261.HMPREF0043_01259	1.394e-11	78.0	COG1595@1|root,COG1595@2|Bacteria,2GM5V@201174|Actinobacteria,4D7Y6@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS2_k127_822610_10	309800.C498_03355	2.886e-19	103.0	COG1061@1|root,arCOG00874@2157|Archaea,2XTYQ@28890|Euryarchaeota,23SWE@183963|Halobacteria	183963|Halobacteria	K	COG1061 DNA or RNA helicases of superfamily II	rad25	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,ResIII
ZZS2_k127_822610_15	1455608.JDTH01000002_gene697	4.364e-09	68.0	COG3372@1|root,arCOG04356@2157|Archaea,2XSTX@28890|Euryarchaeota,23SXA@183963|Halobacteria	183963|Halobacteria	L	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
ZZS2_k127_822610_3	221288.JH992901_gene2575	5.554e-99	335.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1JJMP@1189|Stigonemataceae	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ZZS2_k127_822610_1	1353529.M899_1617	1.609e-117	385.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2MSV0@213481|Bdellovibrionales,2WIY8@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
ZZS2_k127_822610_12	344747.PM8797T_27090	6.22e-14	85.0	COG1413@1|root,COG1413@2|Bacteria,2IYY2@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Prenyltrans
ZZS2_k127_822610_14	1283299.AUKG01000001_gene3168	1.926e-11	72.0	2CGEX@1|root,32Z75@2|Bacteria,2IQEI@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
ZZS2_k127_822610_6	1254432.SCE1572_02480	3.367e-58	231.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43925@68525|delta/epsilon subdivisions,2X47T@28221|Deltaproteobacteria,2YYFQ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS2_k127_822610_8	1396141.BATP01000055_gene2876	1.053e-25	117.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
ZZS2_k127_822610_11	1385519.N801_08230	2.277e-18	98.0	COG4978@1|root,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria,4FHRK@85021|Intrasporangiaceae	201174|Actinobacteria	KT	family transcriptional regulator	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
ZZS2_k127_822610_5	1267533.KB906733_gene3427	3.945e-59	226.0	COG1351@1|root,COG1351@2|Bacteria,3Y3AY@57723|Acidobacteria,2JHXW@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
ZZS2_k127_822610_4	414684.RC1_4113	3.956e-60	219.0	COG0494@1|root,COG0494@2|Bacteria,1RAFY@1224|Proteobacteria,2U66M@28211|Alphaproteobacteria,2JPXF@204441|Rhodospirillales	204441|Rhodospirillales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4743,NUDIX
ZZS2_k127_822610_17	161528.ED21_24861	0.0004646	47.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminomethyltransferase	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
ZZS2_k127_822610_7	575540.Isop_1438	1.491e-56	210.0	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_822610_16	877420.ATVW01000001_gene2103	8.955e-05	49.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,27PJR@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ZZS2_k127_822610_0	671143.DAMO_0393	1.779e-188	616.0	COG0507@1|root,COG0507@2|Bacteria,2NNQY@2323|unclassified Bacteria	2|Bacteria	L	Helix-hairpin-helix containing domain	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
ZZS2_k127_822610_2	1144275.COCOR_05004	4.764e-101	336.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
ZZS2_k127_8241551_7	1382304.JNIL01000001_gene1783	0.0001623	49.0	COG1595@1|root,COG1595@2|Bacteria,1V76Q@1239|Firmicutes,4HJ8B@91061|Bacilli,27AIT@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS2_k127_8241551_8	981085.XP_010097150.1	0.0002386	54.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37SGP@33090|Viridiplantae,3GD5T@35493|Streptophyta,4JRBP@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070647,GO:0071704,GO:0140096,GO:1901564	-	ko:K03360,ko:K10268	ko04111,ko04120,map04111,map04120	M00411	-	-	ko00000,ko00001,ko00002,ko04121	-	-	-	F-box,LRR_6
ZZS2_k127_8241551_5	525904.Tter_0875	2.624e-10	73.0	COG3595@1|root,COG3595@2|Bacteria,2NQ1F@2323|unclassified Bacteria	2|Bacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
ZZS2_k127_8241551_2	1265502.KB905960_gene289	7.809e-80	280.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VHQF@28216|Betaproteobacteria,4ACST@80864|Comamonadaceae	28216|Betaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_8241551_0	1184267.A11Q_2216	4.304e-287	909.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,42PYN@68525|delta/epsilon subdivisions,2MTR4@213481|Bdellovibrionales,2WS4X@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
ZZS2_k127_8241551_9	1123399.AQVE01000027_gene1	0.0007084	52.0	COG0823@1|root,COG1800@1|root,COG0823@2|Bacteria,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8241551_6	156889.Mmc1_1994	7.08e-08	60.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria	1224|Proteobacteria	N	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_8241551_3	215803.DB30_2025	4.521e-24	111.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria,2YV8F@29|Myxococcales	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_8241551_4	500153.JOEK01000013_gene1765	7.848e-12	70.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria	201174|Actinobacteria	L	methylated DNA-protein cysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
ZZS2_k127_8241551_1	926554.KI912625_gene702	3.548e-160	516.0	COG0821@1|root,COG0821@2|Bacteria,1WJ94@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
ZZS2_k127_8310783_3	402777.KB235904_gene3799	8.075e-23	108.0	COG2027@1|root,COG2027@2|Bacteria,1G1K9@1117|Cyanobacteria,1H702@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS2_k127_8310783_2	439235.Dalk_1246	2.151e-54	211.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2MJPN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ZZS2_k127_8310783_4	269798.CHU_1713	3.15e-07	63.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
ZZS2_k127_8310783_0	582402.Hbal_1288	1.301e-268	853.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,43WC4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	COG0308 Aminopeptidase N	pepN	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
ZZS2_k127_8310783_1	1210884.HG799463_gene9396	5.116e-139	463.0	COG1649@1|root,COG1649@2|Bacteria,2IX7D@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
ZZS2_k127_8310783_5	243090.RB12056	3.065e-06	61.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2IZUV@203682|Planctomycetes	203682|Planctomycetes	H	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
ZZS2_k127_8314288_1	378806.STAUR_0120	7.376e-107	367.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,437G6@68525|delta/epsilon subdivisions,2X2NS@28221|Deltaproteobacteria,2YU1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS2_k127_8314288_0	420662.Mpe_A0997	2.995e-130	426.0	COG0387@1|root,COG0387@2|Bacteria,1MWD8@1224|Proteobacteria,2VJQM@28216|Betaproteobacteria,1KJKQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	chaA	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
ZZS2_k127_8314288_2	290397.Adeh_2208	3.426e-68	243.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS2_k127_8314288_6	696281.Desru_2655	3.2e-06	51.0	COG3526@1|root,COG3526@2|Bacteria,1VKFI@1239|Firmicutes,24VMR@186801|Clostridia	186801|Clostridia	O	selT selW selH selenoprotein	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
ZZS2_k127_8314288_5	886293.Sinac_5225	1.234e-25	110.0	COG2363@1|root,COG2363@2|Bacteria,2J0QQ@203682|Planctomycetes	203682|Planctomycetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
ZZS2_k127_8314288_4	1122604.JONR01000011_gene3676	8.511e-39	166.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1S5WE@1236|Gammaproteobacteria,1X3ZI@135614|Xanthomonadales	135614|Xanthomonadales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS2_k127_8314288_3	298653.Franean1_0373	1.014e-44	184.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
ZZS2_k127_8429846_0	1254432.SCE1572_14660	1.246e-75	265.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS2_k127_8429846_1	237368.SCABRO_02220	6.353e-29	128.0	COG1277@1|root,COG1277@2|Bacteria,2J0HW@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
ZZS2_k127_8429846_2	867903.ThesuDRAFT_02089	2.21e-19	103.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia	186801|Clostridia	N	-transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
ZZS2_k127_8429846_3	481448.Minf_0412	4.285e-11	76.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,37FXR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
ZZS2_k127_843125_11	9258.ENSOANP00000025033	4.443e-09	70.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,4985B@7742|Vertebrata,3JEFA@40674|Mammalia	33208|Metazoa	S	inter-alpha-trypsin inhibitor heavy chain	ITIH5	-	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA,VWA_3
ZZS2_k127_843125_9	1283300.ATXB01000002_gene2982	2.608e-59	211.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,1RN7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
ZZS2_k127_843125_6	472759.Nhal_3749	2.103e-89	313.0	COG2253@1|root,COG2253@2|Bacteria,1NJT9@1224|Proteobacteria,1S0YI@1236|Gammaproteobacteria,1WXVW@135613|Chromatiales	135613|Chromatiales	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
ZZS2_k127_843125_4	1385520.N802_02100	3.15e-107	361.0	COG0189@1|root,COG0189@2|Bacteria,2I5WV@201174|Actinobacteria,4FF3F@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_843125_8	1386089.N865_08430	4.202e-64	246.0	COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4FFF6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
ZZS2_k127_843125_7	880073.Calab_1254	7.362e-87	312.0	COG2133@1|root,COG2866@1|root,COG2133@2|Bacteria,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,CHU_C,Glyco_hydro_26,PA14
ZZS2_k127_843125_12	502025.Hoch_1436	5.372e-09	69.0	2AA9Q@1|root,30ZJA@2|Bacteria,1QBSA@1224|Proteobacteria,43E6I@68525|delta/epsilon subdivisions,2WZVD@28221|Deltaproteobacteria,2Z2TX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_843125_10	1300345.LF41_1470	2.644e-47	182.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_843125_3	232346.JHQL01000002_gene932	2.923e-112	376.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,1RY9R@1236|Gammaproteobacteria,1XH7A@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
ZZS2_k127_843125_1	1123508.JH636441_gene3371	1.775e-124	415.0	COG0448@1|root,COG0448@2|Bacteria,2IXP5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS2_k127_843125_5	1496688.ER33_11555	7.359e-103	361.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
ZZS2_k127_843125_2	352165.HMPREF7215_1007	3.302e-118	396.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
ZZS2_k127_843125_0	411464.DESPIG_00920	7.391e-296	977.0	COG0058@1|root,COG0438@1|root,COG0058@2|Bacteria,COG0438@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2M7US@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Glycosyl transferase, family 35	glgP	-	2.4.1.1,2.4.1.11	ko:K00688,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
ZZS2_k127_8498266_8	371042.NG99_08485	1.514e-12	78.0	COG2373@1|root,COG2911@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,1QUUR@1224|Proteobacteria,1T21Q@1236|Gammaproteobacteria,3X82C@551|Erwinia	1236|Gammaproteobacteria	N	Inverse autotransporter, beta-domain	eaeH	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_2,IAT_beta,Invasin_D3,LysM
ZZS2_k127_8498266_9	1090319.KE386571_gene1675	3.011e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,1RIZR@1224|Proteobacteria,2U9QE@28211|Alphaproteobacteria,2K4SE@204457|Sphingomonadales	204457|Sphingomonadales	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS2_k127_8498266_2	1210884.HG799464_gene10754	6.966e-84	287.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS2_k127_8498266_4	1128421.JAGA01000001_gene2394	6.675e-69	248.0	COG0047@1|root,COG0047@2|Bacteria,2NP46@2323|unclassified Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
ZZS2_k127_8498266_0	886293.Sinac_5423	1.376e-269	863.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
ZZS2_k127_8498266_1	1313421.JHBV01000016_gene5558	1.011e-91	308.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1IRN1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
ZZS2_k127_8498266_3	378806.STAUR_3270	1.343e-83	308.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
ZZS2_k127_8498266_6	243365.CV_1546	3.366e-26	117.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,2VK19@28216|Betaproteobacteria,2KQ6K@206351|Neisseriales	206351|Neisseriales	IQ	Psort location Cytoplasmic, score 9.97	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS2_k127_8498266_5	1122613.ATUP01000001_gene1051	1.706e-42	175.0	COG1668@1|root,COG1668@2|Bacteria,1R62N@1224|Proteobacteria,2U1RZ@28211|Alphaproteobacteria,43WE3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
ZZS2_k127_8498266_7	639030.JHVA01000001_gene3308	8.149e-25	108.0	COG4152@1|root,COG4152@2|Bacteria,3Y2NV@57723|Acidobacteria,2JHVX@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
ZZS2_k127_8532437_3	2340.JV46_18860	9.803e-31	136.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J7Q2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS2_k127_8532437_1	439235.Dalk_5144	3.789e-159	522.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
ZZS2_k127_8532437_2	378806.STAUR_3193	7.779e-91	313.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
ZZS2_k127_8532437_0	1449126.JQKL01000047_gene2724	2.407e-257	812.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,26A0R@186813|unclassified Clostridiales	186801|Clostridia	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
ZZS2_k127_8564413_0	1396418.BATQ01000113_gene4680	1.263e-109	360.0	COG1131@1|root,COG1131@2|Bacteria,46U5D@74201|Verrucomicrobia,2IVHU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ZZS2_k127_8564413_1	1403819.BATR01000117_gene4038	4.225e-92	328.0	28HMX@1|root,2Z7WB@2|Bacteria,46V0Q@74201|Verrucomicrobia,2IVBN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8603331_1	1121957.ATVL01000014_gene1459	1.47e-132	442.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8603331_0	1121085.AUCI01000001_gene3727	1.705e-133	440.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_8603331_4	1267533.KB906737_gene1903	4.002e-27	115.0	COG3254@1|root,COG3254@2|Bacteria	2|Bacteria	S	rhamnose metabolic process	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
ZZS2_k127_8603331_2	504472.Slin_0413	1.857e-105	349.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,47N4F@768503|Cytophagia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS2_k127_8603331_3	861299.J421_5602	5.51e-72	247.0	COG1028@1|root,COG1028@2|Bacteria	861299.J421_5602|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8647_4	1379698.RBG1_1C00001G0516	3.95e-107	356.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS2_k127_8647_9	688269.Theth_1658	4.122e-37	162.0	COG0265@1|root,COG0265@2|Bacteria,2GCIH@200918|Thermotogae	200918|Thermotogae	M	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS2_k127_8647_17	153721.MYP_753	0.0009719	52.0	COG0484@1|root,COG0484@2|Bacteria,4NV0E@976|Bacteroidetes,47S5M@768503|Cytophagia	976|Bacteroidetes	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8647_10	1380390.JIAT01000010_gene4585	1.067e-31	137.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
ZZS2_k127_8647_13	595460.RRSWK_03230	5.206e-20	93.0	2E71C@1|root,331K1@2|Bacteria,2J130@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8647_5	305700.B447_02466	3.439e-88	306.0	COG1092@1|root,COG1092@2|Bacteria,1R6GY@1224|Proteobacteria,2VNTR@28216|Betaproteobacteria,2KYCD@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ZZS2_k127_8647_12	794903.OPIT5_22910	3.373e-21	105.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS2_k127_8647_14	1158050.KB895461_gene2922	1.164e-18	101.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CBM_4_9
ZZS2_k127_8647_3	637905.SVI_1691	1.859e-142	479.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
ZZS2_k127_8647_2	637905.SVI_1691	6.814e-154	500.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
ZZS2_k127_8647_16	485915.Dret_1912	0.0002637	53.0	COG0457@1|root,COG0457@2|Bacteria,1MZ66@1224|Proteobacteria,42TQR@68525|delta/epsilon subdivisions,2WQBF@28221|Deltaproteobacteria,2M9ZI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_4
ZZS2_k127_8647_15	1206726.BAFV01000013_gene773	7.143e-10	70.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria,4FV1Y@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
ZZS2_k127_8647_8	880072.Desac_0139	6.999e-49	192.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
ZZS2_k127_8647_6	1396141.BATP01000048_gene3524	2.162e-66	245.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,2ITMX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
ZZS2_k127_8647_0	290397.Adeh_0787	8.107e-169	564.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2YU2M@29|Myxococcales	28221|Deltaproteobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
ZZS2_k127_8647_7	595460.RRSWK_04527	3.385e-53	194.0	COG0353@1|root,COG0353@2|Bacteria,2IXK5@203682|Planctomycetes	203682|Planctomycetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
ZZS2_k127_8647_11	656519.Halsa_0337	8.355e-29	119.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WATQ@53433|Halanaerobiales	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
ZZS2_k127_8647_1	1396141.BATP01000003_gene4967	2.758e-167	560.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
ZZS2_k127_8661239_2	103690.17130018	1.109e-93	323.0	COG0671@1|root,COG0671@2|Bacteria,1GHH3@1117|Cyanobacteria,1HPI6@1161|Nostocales	1117|Cyanobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PAP2
ZZS2_k127_8661239_1	324057.Pjdr2_1476	1.085e-108	366.0	COG1240@1|root,COG1240@2|Bacteria	2|Bacteria	H	magnesium chelatase activity	bchD	-	6.6.1.1	ko:K03404,ko:K07114	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
ZZS2_k127_8661239_4	1278073.MYSTI_03328	4.654e-37	155.0	COG0631@1|root,COG0631@2|Bacteria,1RIGD@1224|Proteobacteria	1224|Proteobacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8661239_3	324057.Pjdr2_1478	2.831e-72	273.0	COG0515@1|root,COG0515@2|Bacteria	324057.Pjdr2_1478|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8661239_5	28564.XP_002486690.1	2.887e-23	117.0	KOG0266@1|root,KOG4155@1|root,KOG0266@2759|Eukaryota,KOG4155@2759|Eukaryota,38B6D@33154|Opisthokonta,3NZ4C@4751|Fungi,3QPCR@4890|Ascomycota,20AVS@147545|Eurotiomycetes,3S3IJ@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	Helo_like_N,NACHT,WD40
ZZS2_k127_8661239_8	1056820.KB900639_gene312	0.0001086	51.0	COG5487@1|root,COG5487@2|Bacteria,1QAYF@1224|Proteobacteria,1T6EC@1236|Gammaproteobacteria,2PQKZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
ZZS2_k127_8661239_0	1131814.JAFO01000001_gene3315	0.0	3348.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3EYBF@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
ZZS2_k127_8661239_7	497964.CfE428DRAFT_0962	3.658e-07	60.0	COG0642@1|root,COG2205@2|Bacteria	497964.CfE428DRAFT_0962|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_8661239_6	1395571.TMS3_0118845	5.806e-21	104.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
ZZS2_k127_921102_2	13349.G1XIH1	6.587e-07	62.0	COG2304@1|root,2REND@2759|Eukaryota,38TNH@33154|Opisthokonta,3P1BG@4751|Fungi,3QSME@4890|Ascomycota	4751|Fungi	S	U-box domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3,Vint,Vwaint
ZZS2_k127_921102_0	402881.Plav_2503	8.755e-46	190.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2U5H1@28211|Alphaproteobacteria,1JQEM@119043|Rhodobiaceae	28211|Alphaproteobacteria	EGP	MFS_1 like family	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
ZZS2_k127_921102_1	1242864.D187_000710	1.096e-08	65.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
ZZS2_k127_925906_13	62928.azo0278	5.557e-06	59.0	2EFNF@1|root,339EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_925906_12	1235802.C823_01243	1.364e-06	60.0	2EB6K@1|root,33579@2|Bacteria,1VFVK@1239|Firmicutes,24T82@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_925906_2	1183438.GKIL_3184	3.748e-116	385.0	COG3367@1|root,COG3367@2|Bacteria,1G2EW@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
ZZS2_k127_925906_3	1265505.ATUG01000001_gene4774	7.062e-93	331.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS2_k127_925906_14	215803.DB30_2422	2.937e-05	57.0	COG0750@1|root,COG4932@1|root,COG0750@2|Bacteria,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS2_k127_925906_5	314230.DSM3645_10062	3.447e-63	240.0	COG1889@1|root,COG1889@2|Bacteria,2J51S@203682|Planctomycetes	203682|Planctomycetes	J	Fibrillarin	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
ZZS2_k127_925906_9	234267.Acid_5864	1.325e-28	133.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS2_k127_925906_10	272134.KB731326_gene216	8.097e-19	102.0	COG4249@1|root,COG4249@2|Bacteria,1G2DA@1117|Cyanobacteria,1H881@1150|Oscillatoriales	1117|Cyanobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
ZZS2_k127_925906_4	1242864.D187_004133	1.675e-64	235.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions,2WQGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
ZZS2_k127_925906_1	765912.Thimo_1384	1.79e-141	457.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1X2A7@135613|Chromatiales	135613|Chromatiales	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
ZZS2_k127_925906_7	290397.Adeh_3999	1.047e-49	186.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,2YXH0@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
ZZS2_k127_925906_0	118163.Ple7327_1120	9.627e-157	503.0	COG0596@1|root,COG0596@2|Bacteria,1G21Y@1117|Cyanobacteria,3VI18@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
ZZS2_k127_925906_8	1120705.FG95_03487	4.313e-36	155.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS2_k127_925906_6	864702.OsccyDRAFT_4934	2.42e-53	201.0	COG1216@1|root,COG1216@2|Bacteria,1G4RU@1117|Cyanobacteria,1HH4K@1150|Oscillatoriales	1117|Cyanobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS2_k127_925906_11	713587.THITH_07655	2.548e-14	73.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1WX51@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
ZZS2_k127_931437_4	502025.Hoch_5731	1.771e-33	150.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
ZZS2_k127_931437_3	96561.Dole_0020	8.561e-41	174.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MI54@213118|Desulfobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
ZZS2_k127_931437_5	1121396.KB893095_gene4382	2.677e-12	81.0	COG1030@1|root,COG1030@2|Bacteria,1MY7A@1224|Proteobacteria,42SJX@68525|delta/epsilon subdivisions,2WPDE@28221|Deltaproteobacteria,2MK8F@213118|Desulfobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
ZZS2_k127_931437_0	575540.Isop_2875	2.296e-112	374.0	COG4864@1|root,COG4864@2|Bacteria,2IXDK@203682|Planctomycetes	203682|Planctomycetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
ZZS2_k127_931437_2	1242864.D187_007363	5.084e-53	211.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_931437_1	661478.OP10G_0622	2.279e-67	250.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS2_k127_983882_1	59374.Fisuc_2838	7.612e-102	335.0	COG1156@1|root,COG1156@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS2_k127_983882_7	1307759.JOMJ01000003_gene1586	9.774e-55	198.0	COG1394@1|root,COG1394@2|Bacteria,1RJCN@1224|Proteobacteria,42THS@68525|delta/epsilon subdivisions,2WQ7A@28221|Deltaproteobacteria,2MC0T@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
ZZS2_k127_983882_0	1307759.JOMJ01000003_gene1587	1.268e-124	445.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42QGM@68525|delta/epsilon subdivisions,2WR5N@28221|Deltaproteobacteria,2MA35@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
ZZS2_k127_983882_8	1121448.DGI_3061	1.863e-53	192.0	COG0636@1|root,COG0636@2|Bacteria,1N04D@1224|Proteobacteria,42TS9@68525|delta/epsilon subdivisions,2WQ2Y@28221|Deltaproteobacteria,2MBJE@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
ZZS2_k127_983882_3	525897.Dbac_0642	1.103e-84	294.0	COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria,42T9W@68525|delta/epsilon subdivisions,2WPRE@28221|Deltaproteobacteria,2M9ZN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS2_k127_983882_10	1125863.JAFN01000001_gene635	1.458e-34	145.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
ZZS2_k127_983882_12	1501230.ET33_04505	0.0001022	49.0	COG2931@1|root,COG2931@2|Bacteria,1V022@1239|Firmicutes,4HFJ6@91061|Bacilli,26SF3@186822|Paenibacillaceae	91061|Bacilli	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS2_k127_983882_11	344747.PM8797T_24886	4.375e-27	121.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
ZZS2_k127_983882_6	7739.XP_002605883.1	5.978e-55	201.0	COG0327@1|root,KOG4131@2759|Eukaryota,39U3J@33154|Opisthokonta,3BE81@33208|Metazoa,3CY48@33213|Bilateria,4842X@7711|Chordata	33208|Metazoa	S	transcription factor binding	NIF3L1	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006355,GO:0007275,GO:0007399,GO:0008134,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0022008,GO:0030154,GO:0030182,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032501,GO:0032502,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	NIF3
ZZS2_k127_983882_4	1499967.BAYZ01000170_gene5483	1.165e-79	297.0	COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_983882_2	1499967.BAYZ01000170_gene5483	6.458e-86	301.0	COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS2_k127_983882_5	429009.Adeg_1292	4.25e-57	220.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS2_k127_983882_9	1210884.HG799465_gene11886	6.322e-52	196.0	COG1482@1|root,COG1482@2|Bacteria,2IZ3A@203682|Planctomycetes	203682|Planctomycetes	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
ZZS2_k127_984022_10	261292.Nit79A3_2985	4.647e-10	70.0	2DGJZ@1|root,2ZWAN@2|Bacteria,1PBDF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS2_k127_984022_2	595460.RRSWK_01966	7.294e-86	304.0	COG3541@1|root,COG3541@2|Bacteria,2IY2V@203682|Planctomycetes	203682|Planctomycetes	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
ZZS2_k127_984022_1	314230.DSM3645_25382	4.594e-105	350.0	COG3541@1|root,COG3541@2|Bacteria,2IXJ3@203682|Planctomycetes	203682|Planctomycetes	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
ZZS2_k127_984022_7	1267005.KB911264_gene3118	9.408e-21	100.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,3N6SG@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	inositol mono-phosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ZZS2_k127_984022_5	324602.Caur_0649	7.128e-57	222.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
ZZS2_k127_984022_11	706587.Desti_0183	2.827e-08	65.0	COG4639@1|root,COG4639@2|Bacteria,1N0U7@1224|Proteobacteria,430C0@68525|delta/epsilon subdivisions,2WVS0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
ZZS2_k127_984022_6	743720.Psefu_2416	8.499e-50	190.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1YXEQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	E	ABC transporter	yecC	GO:0000099,GO:0000101,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363,GO:1901682,GO:1902475,GO:1903825,GO:1905039	3.6.3.21	ko:K02028,ko:K02029,ko:K09972,ko:K10004,ko:K10010	ko02010,ko02020,map02010,map02020	M00230,M00232,M00234,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.17,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
ZZS2_k127_984022_0	247490.KSU1_D0644	1.832e-105	361.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,2IY5R@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
ZZS2_k127_984022_4	171693.BN988_01975	3.671e-57	208.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HED5@91061|Bacilli,23KB8@182709|Oceanobacillus	91061|Bacilli	G	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
ZZS2_k127_984022_3	1173264.KI913949_gene2248	1.518e-63	227.0	2DBNC@1|root,2ZA3D@2|Bacteria,1G1RX@1117|Cyanobacteria,1H88X@1150|Oscillatoriales	1117|Cyanobacteria	S	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
ZZS2_k127_984022_9	228405.HNE_0837	7.752e-14	81.0	COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
## 2870 queries scanned
## Total time (seconds): 345.62300086021423
## Rate: 8.30 q/s