## Sat Oct 19 06:32:21 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/ZZS3_bin.11.fa -m mmseqs --itype genome -o ZZS3_bin.11 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/ZZS3_bin.11 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
ZZS3_k127_1013613_6	1265502.KB905956_gene158	4.025e-93	316.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,4AH3Q@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1013613_0	365046.Rta_02190	6.655e-191	599.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2VHH3@28216|Betaproteobacteria,4AAVW@80864|Comamonadaceae	28216|Betaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ZZS3_k127_1013613_2	365046.Rta_02200	1.569e-166	537.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,4AAGS@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS3_k127_1013613_10	543728.Vapar_0403	9.427e-54	191.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,4AEF4@80864|Comamonadaceae	28216|Betaproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
ZZS3_k127_1013613_7	365046.Rta_02240	1.594e-84	281.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,4ADFG@80864|Comamonadaceae	28216|Betaproteobacteria	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
ZZS3_k127_1013613_1	365046.Rta_02250	4.926e-190	595.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,4ABFX@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
ZZS3_k127_1013613_8	365046.Rta_02260	1.12e-78	264.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,4ADIN@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ZZS3_k127_1013613_9	365046.Rta_02270	1.633e-59	214.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,4ADZZ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
ZZS3_k127_1013613_3	365046.Rta_02280	1.123e-141	458.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,4AAJX@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
ZZS3_k127_1013613_5	365046.Rta_02290	9.103e-97	325.0	COG0811@1|root,COG0811@2|Bacteria,1RFIG@1224|Proteobacteria,2VN8T@28216|Betaproteobacteria,4ADSV@80864|Comamonadaceae	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS3_k127_1013613_11	296591.Bpro_4606	1.126e-50	195.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSMV@28216|Betaproteobacteria,4AEE0@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
ZZS3_k127_1013613_4	365046.Rta_02310	1.133e-133	426.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,4A9UD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
ZZS3_k127_1013848_2	365046.Rta_31160	1.365e-169	534.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,4AB70@80864|Comamonadaceae	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
ZZS3_k127_1013848_8	365046.Rta_31130	3.572e-68	234.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,4AE0A@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
ZZS3_k127_1013848_6	365046.Rta_31120	3.599e-129	421.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,4ACBH@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS3_k127_1013848_3	365046.Rta_31110	1.644e-158	520.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,4A9Z3@80864|Comamonadaceae	28216|Betaproteobacteria	I	phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_1013848_1	365046.Rta_31100	8.737e-185	602.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,2VHKS@28216|Betaproteobacteria,4AC5Z@80864|Comamonadaceae	28216|Betaproteobacteria	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_1013848_10	365046.Rta_31090	8.484e-64	238.0	COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
ZZS3_k127_1013848_0	365046.Rta_31080	1.391e-286	899.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2VJ3Q@28216|Betaproteobacteria,4AB7V@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
ZZS3_k127_1013848_5	365044.Pnap_0912	1.745e-134	432.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2VH10@28216|Betaproteobacteria,4AA1H@80864|Comamonadaceae	28216|Betaproteobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
ZZS3_k127_1013848_7	365046.Rta_31060	1.989e-75	254.0	COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,2VQFF@28216|Betaproteobacteria,4ADT2@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM BLUF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
ZZS3_k127_1013848_4	365046.Rta_31050	1.233e-141	456.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VIZ1@28216|Betaproteobacteria,4AB04@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_1013848_9	338969.Rfer_1303	3.314e-65	225.0	2DBFU@1|root,2Z90B@2|Bacteria,1PI0M@1224|Proteobacteria,2WGPR@28216|Betaproteobacteria,4A9V4@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
ZZS3_k127_1014880_5	296591.Bpro_1202	7.462e-167	530.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH41@28216|Betaproteobacteria,4ABM7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	phbC2	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
ZZS3_k127_1014880_10	296591.Bpro_1204	2.264e-21	103.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
ZZS3_k127_1014880_0	1095769.CAHF01000022_gene141	3.287e-299	943.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,473Z1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
ZZS3_k127_1014880_11	365044.Pnap_0935	6.325e-18	85.0	COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2VY74@28216|Betaproteobacteria,4AIMD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
ZZS3_k127_1014880_6	358220.C380_06830	3.438e-134	433.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,4AAME@80864|Comamonadaceae	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase, NAD-binding	garR1	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_1014880_1	365046.Rta_12700	8.358e-268	829.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2VI2Z@28216|Betaproteobacteria,4AAKE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,NAD_binding_3,SAF
ZZS3_k127_1014880_4	365046.Rta_12710	1.147e-169	548.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,4ABN5@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
ZZS3_k127_1014880_8	365046.Rta_12720	8.674e-101	333.0	COG1802@1|root,COG1802@2|Bacteria,1MY2M@1224|Proteobacteria,2VK5T@28216|Betaproteobacteria,4ADUT@80864|Comamonadaceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_1014880_7	365046.Rta_12730	2.915e-116	381.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria,4AA1E@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carboxylesterase family	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
ZZS3_k127_1014880_2	1123504.JQKD01000012_gene1309	1.933e-187	608.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2VJMM@28216|Betaproteobacteria,4AAG3@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	-	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
ZZS3_k127_1014880_9	365046.Rta_12750	7.799e-63	223.0	29Z5J@1|root,30M3A@2|Bacteria,1RDK0@1224|Proteobacteria,2VS68@28216|Betaproteobacteria,4AE5V@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1014880_3	365046.Rta_12760	5.99e-173	564.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,4AAM8@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS3_k127_1049610_0	365046.Rta_00410	2.323e-113	375.0	COG0392@1|root,COG0392@2|Bacteria,1MXH9@1224|Proteobacteria,2VKP8@28216|Betaproteobacteria,4AB78@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	ybhN	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS3_k127_1049610_1	365046.Rta_00380	9.304e-69	245.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2VMTJ@28216|Betaproteobacteria,4ADKZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4130	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
ZZS3_k127_1049610_2	365046.Rta_00380	6.084e-31	124.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2VMTJ@28216|Betaproteobacteria,4ADKZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4130	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
ZZS3_k127_1049610_3	365046.Rta_00360	2.706e-28	116.0	COG0850@1|root,COG0850@2|Bacteria,1RHVN@1224|Proteobacteria,2VNVN@28216|Betaproteobacteria,4ADMC@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
ZZS3_k127_1064401_24	365046.Rta_33200	2.29e-104	342.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,4AA94@80864|Comamonadaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
ZZS3_k127_1064401_20	365046.Rta_33210	3.916e-130	425.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,4AAN0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
ZZS3_k127_1064401_15	365046.Rta_33220	6.352e-155	507.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,4ABGY@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
ZZS3_k127_1064401_0	365046.Rta_33230	0.0	1067.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,4ABZT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
ZZS3_k127_1064401_17	543728.Vapar_4341	8.073e-140	447.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,4AANT@80864|Comamonadaceae	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
ZZS3_k127_1064401_3	365046.Rta_33250	1.582e-238	759.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,4ABFF@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
ZZS3_k127_1064401_35	365046.Rta_33260	3.631e-46	173.0	COG3017@1|root,COG3017@2|Bacteria,1N2F2@1224|Proteobacteria,2VUJH@28216|Betaproteobacteria,4AF6I@80864|Comamonadaceae	28216|Betaproteobacteria	M	Outer membrane lipoprotein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
ZZS3_k127_1064401_41	358220.C380_04880	1.12e-11	64.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,4A9JU@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ZZS3_k127_1064401_21	365046.Rta_33270	3.713e-121	392.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,4A9JU@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ZZS3_k127_1064401_6	365046.Rta_33280	4.035e-187	587.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,4ABG6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
ZZS3_k127_1064401_26	365046.Rta_33290	2.818e-102	338.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,4ABGU@80864|Comamonadaceae	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
ZZS3_k127_1064401_22	365046.Rta_33300	8.7e-111	360.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,4ABYV@80864|Comamonadaceae	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
ZZS3_k127_1064401_42	595537.Varpa_5001	0.0004237	48.0	2DSHP@1|root,33G5U@2|Bacteria,1NNEU@1224|Proteobacteria,2VYCC@28216|Betaproteobacteria,4AFV8@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1064401_36	358220.C380_04860	1.426e-41	169.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,4AEXM@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
ZZS3_k127_1064401_12	365046.Rta_33330	1.895e-164	527.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VK1U@28216|Betaproteobacteria,4ACNW@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_1064401_16	365046.Rta_33340	1.898e-150	479.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2VIGP@28216|Betaproteobacteria,4AC6E@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
ZZS3_k127_1064401_9	365046.Rta_33350	2.091e-167	547.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,4AA2A@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ZZS3_k127_1064401_19	365046.Rta_33360	3.56e-130	438.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,4AAVR@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ZZS3_k127_1064401_2	365046.Rta_33370	5.418e-251	785.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VKA4@28216|Betaproteobacteria,4AC1M@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_1064401_1	365046.Rta_33380	2.435e-251	782.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VKAQ@28216|Betaproteobacteria,4ABTJ@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_1064401_7	595537.Varpa_5013	2.672e-175	564.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria,4ABR3@80864|Comamonadaceae	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1064401_34	983917.RGE_46250	1.568e-59	214.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VS5A@28216|Betaproteobacteria,1KKX9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
ZZS3_k127_1064401_29	365046.Rta_33400	4.846e-81	292.0	COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,2VQK8@28216|Betaproteobacteria,4ADMB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS3_k127_1064401_30	365046.Rta_33470	7.914e-80	280.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,4ABJ9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS3_k127_1064401_28	365046.Rta_33480	1.439e-81	275.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,4ADP4@80864|Comamonadaceae	28216|Betaproteobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
ZZS3_k127_1064401_5	365046.Rta_33500	1.041e-187	616.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,4AAEI@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS3_k127_1064401_4	365046.Rta_33510	3.384e-225	706.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,4AABQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS3_k127_1064401_11	365046.Rta_33520	8.737e-166	528.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,4A9JP@80864|Comamonadaceae	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
ZZS3_k127_1064401_37	365046.Rta_33610	1.533e-29	123.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,4AG36@80864|Comamonadaceae	28216|Betaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
ZZS3_k127_1064401_33	365046.Rta_33620	6.109e-65	228.0	COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,2VRIU@28216|Betaproteobacteria,4AE3C@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
ZZS3_k127_1064401_10	365046.Rta_33630	3.28e-167	529.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,4ACEU@80864|Comamonadaceae	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
ZZS3_k127_1064401_39	1249627.D779_1409	9.105e-25	120.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,1T1G8@1236|Gammaproteobacteria,1WXZN@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
ZZS3_k127_1064401_23	543728.Vapar_4380	6.07e-109	358.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,2VPH7@28216|Betaproteobacteria,4AEFY@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation,HEAT_2
ZZS3_k127_1064401_31	365046.Rta_33650	2.206e-79	286.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,4ADHT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Electron transport protein SCO1 SenC	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
ZZS3_k127_1064401_14	365046.Rta_33660	1.037e-158	504.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,4AAA5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
ZZS3_k127_1064401_8	365046.Rta_33670	2.284e-168	537.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2VJ3C@28216|Betaproteobacteria,4AB9J@80864|Comamonadaceae	28216|Betaproteobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
ZZS3_k127_1064401_27	365046.Rta_33680	5.742e-100	331.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria,4A9Y4@80864|Comamonadaceae	28216|Betaproteobacteria	S	signal sequence binding	sco1	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1064401_32	365046.Rta_33690	1.895e-77	270.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,4ADJM@80864|Comamonadaceae	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
ZZS3_k127_1064401_38	365044.Pnap_0883	4.01e-27	124.0	2E53D@1|root,32ZWH@2|Bacteria,1N979@1224|Proteobacteria,2VVRY@28216|Betaproteobacteria,4AFBB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
ZZS3_k127_1064401_13	365046.Rta_33710	9.288e-164	518.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,4AA6B@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
ZZS3_k127_1064401_40	365046.Rta_33720	7.644e-17	91.0	2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,2VXNC@28216|Betaproteobacteria,4AFMF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2970)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2970
ZZS3_k127_1064401_25	365046.Rta_33730	1.459e-102	335.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,4AADH@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Cytochrome c oxidase assembly protein CtaG Cox11	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
ZZS3_k127_1064401_18	365046.Rta_33750	1.682e-137	438.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,4AAW8@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
ZZS3_k127_1090713_6	365046.Rta_31990	5.913e-59	225.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS3_k127_1090713_2	365046.Rta_31980	1.671e-137	453.0	COG0265@1|root,COG0265@2|Bacteria,1QWA4@1224|Proteobacteria,2VK6X@28216|Betaproteobacteria,4A9X2@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
ZZS3_k127_1090713_3	365046.Rta_31970	1.026e-129	420.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria,4AA5J@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM TatD-related deoxyribonuclease	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ZZS3_k127_1090713_4	365046.Rta_31950	6.939e-127	409.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,4AB2V@80864|Comamonadaceae	28216|Betaproteobacteria	E	Spermidine synthase	speE1	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
ZZS3_k127_1090713_0	365046.Rta_31940	0.0	1041.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AA92@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	gspE1	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS3_k127_1090713_5	358220.C380_06520	3.644e-70	241.0	29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,4AE1W@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
ZZS3_k127_1090713_1	365046.Rta_31900	3.437e-270	835.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAHM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA4	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
ZZS3_k127_1097760_0	1366050.N234_10625	0.0	1454.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2W1MJ@28216|Betaproteobacteria,1KC8V@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
ZZS3_k127_1097760_2	748247.AZKH_2577	7.204e-146	511.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,2KV30@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane efflux protein	-	-	-	ko:K18903	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17.3.3	-	-	OEP
ZZS3_k127_1097760_1	420662.Mpe_A0868	0.0	1386.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ2M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	AcrB/AcrD/AcrF family	bepE_1	-	-	ko:K03296,ko:K18138,ko:K18902	ko01501,ko01503,map01501,map01503	M00647,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_1105439_6	595537.Varpa_3533	1.911e-136	444.0	COG0501@1|root,COG0501@2|Bacteria,1R86U@1224|Proteobacteria,2VZKA@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_1105439_0	595537.Varpa_3534	0.0	2139.0	COG0507@1|root,COG1112@1|root,COG3831@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG3831@2|Bacteria,1MWMG@1224|Proteobacteria,2VHWC@28216|Betaproteobacteria,4ADAU@80864|Comamonadaceae	28216|Betaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559,GreA_GreB,IstB_IS21,WGR
ZZS3_k127_1105439_7	661478.OP10G_0334	1.697e-118	386.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
ZZS3_k127_1105439_1	1048339.KB913029_gene4089	1.802e-256	826.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2GM4U@201174|Actinobacteria,4EUPX@85013|Frankiales	201174|Actinobacteria	KT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
ZZS3_k127_1105439_8	1320556.AVBP01000020_gene225	2.184e-98	329.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,43JDB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_1105439_9	338969.Rfer_1706	1.178e-46	173.0	COG1917@1|root,COG1917@2|Bacteria,1RH8X@1224|Proteobacteria,2VSGV@28216|Betaproteobacteria,4AFZE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_1105439_3	1100720.ALKN01000035_gene958	4.72e-217	688.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2W181@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_1105439_10	1100720.ALKN01000035_gene951	2.36e-39	150.0	COG4627@1|root,COG4627@2|Bacteria,1N8RI@1224|Proteobacteria,2VUSF@28216|Betaproteobacteria,4AEY5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
ZZS3_k127_1105439_5	296591.Bpro_2064	3.963e-145	468.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2VMB9@28216|Betaproteobacteria,4AB9S@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.37	ko:K04098	ko00361,ko00362,ko01100,ko01120,map00361,map00362,map01100,map01120	-	R03891,R04061	RC00388,RC01016	ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
ZZS3_k127_1105439_4	1157708.KB907457_gene2570	2.972e-154	492.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VIE3@28216|Betaproteobacteria,4AC9Y@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_1105439_2	1100720.ALKN01000044_gene2000	1.81e-248	779.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VMYQ@28216|Betaproteobacteria,4AD4B@80864|Comamonadaceae	28216|Betaproteobacteria	CH	FAD binding domain	-	-	1.14.13.20	ko:K10676	ko00361,ko01100,ko01120,ko01220,map00361,map01100,map01120,map01220	-	R03997,R05441	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_1112927_0	1408224.SAMCCGM7_c0036	9.311e-219	692.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,4B7GV@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	epoxide hydrolase	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
ZZS3_k127_1112927_5	1500257.JQNM01000001_gene3340	1.734e-48	183.0	COG1917@1|root,COG1917@2|Bacteria,1RIG6@1224|Proteobacteria,2VG1C@28211|Alphaproteobacteria,4BNFK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_1112927_7	335283.Neut_0038	8.343e-08	59.0	2C3D2@1|root,33DT8@2|Bacteria,1NIIF@1224|Proteobacteria,2VXZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4148
ZZS3_k127_1112927_4	543728.Vapar_5351	1.589e-74	269.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2VQKU@28216|Betaproteobacteria,4ADGZ@80864|Comamonadaceae	28216|Betaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
ZZS3_k127_1112927_6	1198452.Jab_2c14530	2.362e-37	151.0	COG2197@1|root,COG2197@2|Bacteria,1QW7K@1224|Proteobacteria,2WBIV@28216|Betaproteobacteria,477FH@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ZZS3_k127_1112927_3	1198452.Jab_2c32280	1.169e-131	428.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2VHJW@28216|Betaproteobacteria,475ZN@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS3_k127_1112927_2	365046.Rta_06360	6.365e-151	487.0	COG1225@1|root,COG1225@2|Bacteria,1QZDS@1224|Proteobacteria	1224|Proteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS3_k127_1112927_1	420324.KI912082_gene6957	8.462e-178	558.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,1JUZ2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
ZZS3_k127_1114054_10	1504672.669784564	1.156e-12	67.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,2VIYU@28216|Betaproteobacteria,4ACCY@80864|Comamonadaceae	28216|Betaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
ZZS3_k127_1114054_0	365046.Rta_36400	2.109e-205	656.0	COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria,4A9NP@80864|Comamonadaceae	28216|Betaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
ZZS3_k127_1114054_4	358220.C380_21770	1.808e-77	265.0	2EDY7@1|root,30V4M@2|Bacteria,1RGIS@1224|Proteobacteria,2VQT2@28216|Betaproteobacteria,4AE7R@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1114054_8	365046.Rta_36420	1.65e-43	164.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,4AEN7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	DUF1775,PCuAC
ZZS3_k127_1114054_6	358220.C380_21780	7.116e-73	255.0	COG4549@1|root,COG4549@2|Bacteria,1NC7K@1224|Proteobacteria,2VVBX@28216|Betaproteobacteria,4ADXW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unkown function (DUF1775)	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	DUF1775
ZZS3_k127_1114054_9	365046.Rta_36440	6.14e-23	104.0	2EAX8@1|root,334YF@2|Bacteria,1N9GE@1224|Proteobacteria,2VVUS@28216|Betaproteobacteria,4AEVV@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2946
ZZS3_k127_1114054_2	365046.Rta_36460	5.115e-149	477.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2VIMS@28216|Betaproteobacteria,4ADED@80864|Comamonadaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS3_k127_1114054_5	543728.Vapar_4776	3.09e-77	271.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2VQAJ@28216|Betaproteobacteria,4ADT8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM GumN family protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
ZZS3_k127_1114054_7	296591.Bpro_0448	2.406e-68	246.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2VR9W@28216|Betaproteobacteria,4AE4J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_1114054_3	365046.Rta_36480	1.53e-101	337.0	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2VRQ8@28216|Betaproteobacteria,4ADUM@80864|Comamonadaceae	28216|Betaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
ZZS3_k127_1114054_1	365046.Rta_36490	7.77e-197	619.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2VHBN@28216|Betaproteobacteria,4AANJ@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
ZZS3_k127_114723_2	358220.C380_01785	1.734e-124	415.0	COG3618@1|root,COG3618@2|Bacteria,1QWWJ@1224|Proteobacteria,2VMAE@28216|Betaproteobacteria,4AAG5@80864|Comamonadaceae	28216|Betaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS3_k127_114723_3	365046.Rta_03090	3.687e-121	395.0	COG0412@1|root,COG3917@1|root,COG0412@2|Bacteria,COG3917@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,4ACGY@80864|Comamonadaceae	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
ZZS3_k127_114723_4	1100721.ALKO01000027_gene357	1.326e-115	377.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VK1C@28216|Betaproteobacteria,4ABW6@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_114723_7	365046.Rta_03070	1.859e-65	239.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2VTGX@28216|Betaproteobacteria,4AJFH@80864|Comamonadaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
ZZS3_k127_114723_5	365044.Pnap_0186	4.41e-96	329.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria,4AA09@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Multiple antibiotic resistance (MarC)-related	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
ZZS3_k127_114723_1	1504672.669783639	1.465e-124	433.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AAGH@80864|Comamonadaceae	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
ZZS3_k127_114723_6	977880.RALTA_B0823	1.446e-86	298.0	COG0583@1|root,COG0583@2|Bacteria,1R487@1224|Proteobacteria,2VMMV@28216|Betaproteobacteria,1K2G5@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_114723_0	595537.Varpa_0729	7.111e-251	786.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria,4ABXK@80864|Comamonadaceae	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
ZZS3_k127_114723_8	365046.Rta_35140	1.267e-56	199.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,4AECC@80864|Comamonadaceae	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
ZZS3_k127_114723_9	1286631.X805_22820	6.691e-38	142.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,1KJQF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
ZZS3_k127_1170914_7	742159.HMPREF0004_3332	8.415e-122	394.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VK61@28216|Betaproteobacteria,3T6ZJ@506|Alcaligenaceae	28216|Betaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	gnl	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS3_k127_1170914_10	296591.Bpro_1419	9.447e-100	332.0	COG1802@1|root,COG1802@2|Bacteria,1RCFJ@1224|Proteobacteria,2VIZT@28216|Betaproteobacteria,4AAZI@80864|Comamonadaceae	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_1170914_2	296591.Bpro_1420	4.095e-230	719.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VJ87@28216|Betaproteobacteria,4ABTN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
ZZS3_k127_1170914_8	614083.AWQR01000022_gene116	5.471e-112	375.0	COG4286@1|root,COG4286@2|Bacteria,1MVTY@1224|Proteobacteria,2W2U2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
ZZS3_k127_1170914_3	296591.Bpro_1422	2.704e-218	694.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2VK9D@28216|Betaproteobacteria,4A9VN@80864|Comamonadaceae	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_1170914_0	365046.Rta_32660	0.0	1045.0	COG0624@1|root,COG3195@1|root,COG0624@2|Bacteria,COG3195@2|Bacteria,1MVUX@1224|Proteobacteria,2VIGB@28216|Betaproteobacteria,4AB68@80864|Comamonadaceae	28216|Betaproteobacteria	E	Amidase, hydantoinase carbamoylase family	uraD	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,OHCU_decarbox,Peptidase_M20,Peptidase_M28
ZZS3_k127_1170914_5	762376.AXYL_01642	3.239e-187	601.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2VJQR@28216|Betaproteobacteria,3T1FV@506|Alcaligenaceae	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.41	ko:K01452	ko00520,ko01100,map00520,map01100	-	R02333	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
ZZS3_k127_1170914_11	595537.Varpa_4539	7.185e-91	311.0	COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,2VIQU@28216|Betaproteobacteria,4AAGZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_1170914_13	614083.AWQR01000002_gene2979	5.795e-50	194.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2VUG8@28216|Betaproteobacteria,4ADZY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
ZZS3_k127_1170914_12	365046.Rta_32610	8.187e-62	217.0	COG0810@1|root,COG0810@2|Bacteria,1RFAG@1224|Proteobacteria,2VRH3@28216|Betaproteobacteria,4AE8G@80864|Comamonadaceae	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2
ZZS3_k127_1170914_9	358220.C380_05395	2.15e-108	356.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2VKME@28216|Betaproteobacteria,4ABF4@80864|Comamonadaceae	28216|Betaproteobacteria	O	TIGRFAM Xanthine dehydrogenase accessory protein XdhC	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
ZZS3_k127_1170914_4	296591.Bpro_1430	3.684e-209	657.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,4ABH2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
ZZS3_k127_1170914_1	296591.Bpro_1434	2.189e-235	734.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,4AANN@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM MOFRL domain protein	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
ZZS3_k127_1170914_6	365046.Rta_05890	4.267e-144	463.0	COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,2VHIJ@28216|Betaproteobacteria,4ABDK@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_1175260_4	1217720.ALOX01000029_gene3801	4.877e-163	529.0	COG2072@1|root,COG2072@2|Bacteria,1MUKW@1224|Proteobacteria,2TQVE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
ZZS3_k127_1175260_12	1157708.KB907459_gene1993	1.089e-99	333.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,2VQDI@28216|Betaproteobacteria,4AJ7V@80864|Comamonadaceae	28216|Betaproteobacteria	G	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
ZZS3_k127_1175260_8	1123504.JQKD01000044_gene2134	1.272e-144	463.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,4A9QE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
ZZS3_k127_1175260_11	365046.Rta_09510	6.026e-106	362.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,4ACME@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
ZZS3_k127_1175260_7	365046.Rta_09520	8.385e-148	485.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,4A9RI@80864|Comamonadaceae	28216|Betaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS3_k127_1175260_5	864051.BurJ1DRAFT_1685	1.907e-155	519.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_1175260_15	864051.BurJ1DRAFT_1686	1.785e-84	286.0	COG0410@1|root,COG0410@2|Bacteria,1R5HF@1224|Proteobacteria,2VS8X@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_1175260_14	1110502.TMO_0803	1.048e-85	306.0	COG0411@1|root,COG0411@2|Bacteria,1R5MA@1224|Proteobacteria,2TV7Q@28211|Alphaproteobacteria,2JRSP@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_1175260_10	864051.BurJ1DRAFT_1688	1.23e-111	371.0	COG4177@1|root,COG4177@2|Bacteria,1QF6I@1224|Proteobacteria,2VRRP@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
ZZS3_k127_1175260_9	864051.BurJ1DRAFT_1689	1.069e-124	406.0	COG0559@1|root,COG0559@2|Bacteria,1MYEW@1224|Proteobacteria,2VKZN@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_1175260_0	864051.BurJ1DRAFT_1690	6.709e-230	719.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2VKVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	abc-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_1175260_6	296591.Bpro_1061	5.078e-154	511.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,2VKM3@28216|Betaproteobacteria,4AG3Q@80864|Comamonadaceae	28216|Betaproteobacteria	T	7TMR-DISM extracellular 2	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
ZZS3_k127_1175260_2	365046.Rta_09540	1.067e-203	644.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,4AADM@80864|Comamonadaceae	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ZZS3_k127_1175260_3	365046.Rta_09550	2.072e-198	621.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,4ABM6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cobalamin synthesis protein P47K	yjiA_1	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
ZZS3_k127_1175260_13	365046.Rta_09560	8.834e-93	319.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,4A9U7@80864|Comamonadaceae	28216|Betaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
ZZS3_k127_1175260_1	365046.Rta_09570	5.381e-215	703.0	COG3170@1|root,COG3170@2|Bacteria,1QXJ7@1224|Proteobacteria,2WH5D@28216|Betaproteobacteria,4AAZK@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
ZZS3_k127_1175260_16	365046.Rta_09580	2.39e-08	55.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,4ABQ9@80864|Comamonadaceae	28216|Betaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
ZZS3_k127_1180759_15	365046.Rta_12930	8.188e-21	100.0	COG3652@1|root,COG3652@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF2383,DUF4142
ZZS3_k127_1180759_14	690850.Desaf_3713	3.816e-22	102.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria,2MCWR@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
ZZS3_k127_1180759_7	1123255.JHYS01000009_gene2342	3.625e-109	390.0	COG1801@1|root,COG1801@2|Bacteria,1N06I@1224|Proteobacteria,2VJZZ@28216|Betaproteobacteria,4AJ47@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS3_k127_1180759_0	742159.HMPREF0004_4442	4.88e-303	960.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VM2H@28216|Betaproteobacteria,3T57X@506|Alcaligenaceae	28216|Betaproteobacteria	L	Superfamily I DNA and RNA helicases	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS3_k127_1180759_10	365046.Rta_12960	1.199e-88	299.0	COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,2VPIZ@28216|Betaproteobacteria,4ADBF@80864|Comamonadaceae	28216|Betaproteobacteria	T	Protein tyrosine serine phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
ZZS3_k127_1180759_8	365046.Rta_12970	4.758e-109	362.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria	1224|Proteobacteria	S	COG1073 hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Hydrolase_4
ZZS3_k127_1180759_9	365046.Rta_12970	1.186e-90	306.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria	1224|Proteobacteria	S	COG1073 hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Hydrolase_4
ZZS3_k127_1180759_2	365046.Rta_12990	5.247e-190	603.0	COG0025@1|root,COG0025@2|Bacteria,1QA7B@1224|Proteobacteria,2VHPR@28216|Betaproteobacteria,4ACQT@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
ZZS3_k127_1180759_12	543728.Vapar_2007	6.105e-34	137.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2VS4H@28216|Betaproteobacteria,4ADYD@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_1180759_4	365046.Rta_13050	2.957e-148	474.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,4AAE1@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
ZZS3_k127_1180759_3	365046.Rta_13060	3.8e-149	488.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,4ABTF@80864|Comamonadaceae	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
ZZS3_k127_1180759_1	365046.Rta_13070	3.481e-215	671.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,4AAK2@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske 2Fe-2S	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS3_k127_1180759_13	365046.Rta_13080	2.722e-30	120.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,4AFD9@80864|Comamonadaceae	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
ZZS3_k127_1180759_5	365046.Rta_13090	4.122e-127	414.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,4AB76@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS3_k127_1180759_6	365046.Rta_13100	3.848e-126	409.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,4A9JK@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
ZZS3_k127_1188213_1	365046.Rta_21030	3.123e-136	441.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,4AA85@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
ZZS3_k127_1188213_9	358220.C380_11570	1.281e-59	213.0	COG3597@1|root,COG3597@2|Bacteria,1RKKI@1224|Proteobacteria,2VRD5@28216|Betaproteobacteria,4AE4C@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1188213_10	1111728.ATYS01000016_gene4632	1.102e-05	52.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1188213_2	365046.Rta_21040	4.659e-132	426.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,4AAIJ@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
ZZS3_k127_1188213_4	365046.Rta_21050	6.186e-97	332.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,4AC9U@80864|Comamonadaceae	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
ZZS3_k127_1188213_8	365046.Rta_21060	2.446e-64	226.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,4ADHE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
ZZS3_k127_1188213_0	365046.Rta_21070	4.111e-221	692.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,4A9JN@80864|Comamonadaceae	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
ZZS3_k127_1188213_5	365046.Rta_21090	2.559e-89	301.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,2WGZN@28216|Betaproteobacteria,4ADRS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
ZZS3_k127_1188213_3	1192124.LIG30_1774	7.274e-110	363.0	COG1216@1|root,COG1216@2|Bacteria,1R4ZP@1224|Proteobacteria,2VMIZ@28216|Betaproteobacteria,1KD2D@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_1188213_7	1192124.LIG30_1775	3.82e-71	256.0	COG3307@1|root,COG3307@2|Bacteria,1REUQ@1224|Proteobacteria,2VRIN@28216|Betaproteobacteria,1K60D@119060|Burkholderiaceae	28216|Betaproteobacteria	M	O-antigen	rfaL	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
ZZS3_k127_1188213_6	1276756.AUEX01000003_gene840	1.125e-78	273.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,4A9XP@80864|Comamonadaceae	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS3_k127_1201225_0	365046.Rta_37350	0.0	1307.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4ACRA@80864|Comamonadaceae	28216|Betaproteobacteria	NU	General secretory system II, protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GAF,T2SSE,T2SSE_N
ZZS3_k127_1201225_6	365046.Rta_37360	1.677e-150	477.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,4AA3Q@80864|Comamonadaceae	28216|Betaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
ZZS3_k127_1201225_2	614083.AWQR01000009_gene733	0.0	1078.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
ZZS3_k127_1201225_9	365046.Rta_37370	6.185e-104	342.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,4ADC0@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
ZZS3_k127_1201225_7	365046.Rta_37380	3.87e-144	460.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,4ABI2@80864|Comamonadaceae	28216|Betaproteobacteria	T	protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS3_k127_1201225_1	614083.AWQR01000009_gene736	0.0	1233.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
ZZS3_k127_1201225_8	365046.Rta_37400	1.124e-111	365.0	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,4ABA3@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
ZZS3_k127_1201225_4	365046.Rta_37410	1.063e-183	575.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,4AB9Z@80864|Comamonadaceae	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
ZZS3_k127_1201225_3	365046.Rta_37420	8.14e-221	697.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,4AA82@80864|Comamonadaceae	28216|Betaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
ZZS3_k127_1201225_5	365046.Rta_37430	7.113e-158	501.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,4A9MJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
ZZS3_k127_1203043_4	864051.BurJ1DRAFT_2940	1.146e-148	476.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VMR0@28216|Betaproteobacteria,1KNUX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
ZZS3_k127_1203043_1	864051.BurJ1DRAFT_2939	0.0	1062.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,1KNFB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_1203043_7	398578.Daci_2801	3.597e-81	286.0	COG4126@1|root,COG4126@2|Bacteria,1MWVG@1224|Proteobacteria,2VQZ1@28216|Betaproteobacteria,4ADQ4@80864|Comamonadaceae	28216|Betaproteobacteria	E	Asp Glu Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1203043_0	1268622.AVS7_02546	0.0	1315.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,4ABBZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
ZZS3_k127_1203043_3	1268622.AVS7_02547	4.539e-177	560.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
ZZS3_k127_1203043_2	1123504.JQKD01000013_gene1008	2.645e-236	737.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VJJ6@28216|Betaproteobacteria,4AAE9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
ZZS3_k127_1203043_6	1268622.AVS7_02551	6.086e-127	414.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2VJY7@28216|Betaproteobacteria,4AB25@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_1203043_8	224911.27352151	1.068e-76	270.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	bcsY	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ZZS3_k127_1203043_5	365046.Rta_15450	4.449e-127	407.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,4ABMU@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
ZZS3_k127_1248012_0	296591.Bpro_0675	0.0	1088.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,4ACB9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
ZZS3_k127_1248012_5	365046.Rta_07620	6.431e-67	231.0	COG1522@1|root,COG1522@2|Bacteria,1RD38@1224|Proteobacteria,2VRBA@28216|Betaproteobacteria,4ADWA@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
ZZS3_k127_1248012_7	1205680.CAKO01000040_gene777	7.832e-22	106.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS3_k127_1248012_1	365046.Rta_07530	5.284e-223	715.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,4AAIK@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
ZZS3_k127_1248012_4	365046.Rta_07520	2.054e-77	291.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,2VR1F@28216|Betaproteobacteria,4AE93@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1248012_3	420662.Mpe_A0228	1.128e-90	325.0	COG0477@1|root,COG2814@2|Bacteria,1R8UR@1224|Proteobacteria,2VVAT@28216|Betaproteobacteria,1KMDP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_1248012_2	365046.Rta_07500	2.909e-203	634.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria,4ABA1@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_1248012_6	365046.Rta_07490	2.575e-58	207.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,2VSY0@28216|Betaproteobacteria,4AEM1@80864|Comamonadaceae	28216|Betaproteobacteria	F	TIGRFAM Carbohydrate kinase, thermoresistant glucokinase	idnK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_33,SKI
ZZS3_k127_1248012_8	391735.Veis_2647	1.857e-05	51.0	2C41D@1|root,3354J@2|Bacteria,1NFI5@1224|Proteobacteria,2VX1A@28216|Betaproteobacteria,4AFG5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2917)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2917
ZZS3_k127_1307347_2	365046.Rta_00810	1.956e-182	573.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VN65@28216|Betaproteobacteria,4A9Q0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
ZZS3_k127_1307347_3	365046.Rta_00780	1.318e-154	492.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,4AAXW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
ZZS3_k127_1307347_7	365046.Rta_00770	9.002e-93	325.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,2VQ1M@28216|Betaproteobacteria,4ADM5@80864|Comamonadaceae	28216|Betaproteobacteria	S	esterase of the alpha beta	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
ZZS3_k127_1307347_4	614083.AWQR01000007_gene384	3.825e-140	460.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,4AAI0@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
ZZS3_k127_1307347_5	1223521.BBJX01000002_gene2785	5.818e-108	354.0	COG1280@1|root,COG1280@2|Bacteria,1RA1G@1224|Proteobacteria,2VKHI@28216|Betaproteobacteria,4AAFJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Lysine exporter protein (Lyse ygga)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
ZZS3_k127_1307347_9	887062.HGR_14729	3.836e-86	295.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,4AC2M@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
ZZS3_k127_1307347_0	365046.Rta_00730	0.0	1148.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,4AAPK@80864|Comamonadaceae	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
ZZS3_k127_1307347_8	365046.Rta_00700	1.011e-91	304.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria,4ADH2@80864|Comamonadaceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS3_k127_1307347_12	1504672.669784915	1.552e-46	173.0	2DIFQ@1|root,30348@2|Bacteria,1N288@1224|Proteobacteria,2W1RB@28216|Betaproteobacteria,4AHF1@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1307347_1	296591.Bpro_0215	1.215e-182	583.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,2VJ4S@28216|Betaproteobacteria,4AGIW@80864|Comamonadaceae	28216|Betaproteobacteria	P	Cation transport protein	trkG	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
ZZS3_k127_1307347_6	296591.Bpro_0214	4.223e-96	320.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,2VMVC@28216|Betaproteobacteria,4AHBY@80864|Comamonadaceae	28216|Betaproteobacteria	P	TrkA-C domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
ZZS3_k127_1307347_13	292.DM42_915	1.168e-40	152.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,1K9G0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
ZZS3_k127_1307347_10	216595.PFLU_4284	1.809e-57	213.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RQ3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS_9
ZZS3_k127_1307347_11	261292.Nit79A3_0852	1.285e-50	182.0	COG3437@1|root,COG3437@2|Bacteria,1PDX2@1224|Proteobacteria,2VMIS@28216|Betaproteobacteria,372X7@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
ZZS3_k127_1328970_7	365046.Rta_25080	3.848e-88	294.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4ABI0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ZZS3_k127_1328970_2	1276756.AUEX01000014_gene2910	2.135e-220	687.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,4AB6A@80864|Comamonadaceae	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
ZZS3_k127_1328970_8	365046.Rta_25100	1.447e-39	154.0	COG2194@1|root,COG2194@2|Bacteria	2|Bacteria	T	sulfuric ester hydrolase activity	kbaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007,GO:0071944	2.7.8.43	ko:K03760,ko:K06349,ko:K11537,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	2.A.1.10.2	-	-	CBP_BcsG,KbaA
ZZS3_k127_1328970_3	365046.Rta_25110	1.42e-188	595.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,4AAGA@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Radical SAM domain protein	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS3_k127_1328970_6	365046.Rta_25130	3.371e-99	325.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,4AB7R@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
ZZS3_k127_1328970_0	365046.Rta_25140	2.103e-250	778.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2VHFR@28216|Betaproteobacteria,4AAGK@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
ZZS3_k127_1328970_4	365046.Rta_25150	5.542e-177	564.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2VHSQ@28216|Betaproteobacteria,4AD1I@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
ZZS3_k127_1328970_5	365046.Rta_25160	5.065e-170	537.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,4ABSG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
ZZS3_k127_1328970_1	365046.Rta_25170	2.084e-227	707.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,4A9JW@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
ZZS3_k127_1363165_3	365046.Rta_36490	1.855e-162	513.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2VHBN@28216|Betaproteobacteria,4AANJ@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
ZZS3_k127_1363165_0	365046.Rta_36500	2.373e-249	777.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VII8@28216|Betaproteobacteria,4AC8U@80864|Comamonadaceae	28216|Betaproteobacteria	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	otsA	-	2.4.1.15,2.4.1.213,2.4.1.347	ko:K00697,ko:K03692	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
ZZS3_k127_1363165_1	266264.Rmet_5795	1.577e-218	691.0	COG1297@1|root,COG1297@2|Bacteria,1NQQP@1224|Proteobacteria	1224|Proteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
ZZS3_k127_1363165_2	365046.Rta_36540	1e-191	601.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2VGZX@28216|Betaproteobacteria,4AA6Y@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (Faa) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_1363165_4	365046.Rta_36550	4.283e-128	413.0	COG1414@1|root,COG1414@2|Bacteria,1Q7BI@1224|Proteobacteria,2VK7Y@28216|Betaproteobacteria,4AAJZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_1363165_5	358220.C380_02400	1.878e-54	213.0	COG3087@1|root,COG3087@2|Bacteria,1RCA5@1224|Proteobacteria,2VTK8@28216|Betaproteobacteria,4AJVR@80864|Comamonadaceae	28216|Betaproteobacteria	D	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
ZZS3_k127_1363165_6	365046.Rta_36570	1.583e-14	73.0	2E6W9@1|root,32SGN@2|Bacteria,1MZMD@1224|Proteobacteria,2VU0A@28216|Betaproteobacteria,4AEVU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3567)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3567
ZZS3_k127_1379298_6	404589.Anae109_0627	6.167e-12	70.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ZZS3_k127_1379298_4	365046.Rta_25855	7.063e-27	115.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VRW4@28216|Betaproteobacteria,4AE7N@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_1379298_2	296591.Bpro_4182	3.271e-57	202.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,4AEE4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
ZZS3_k127_1379298_0	365046.Rta_05750	3.984e-89	301.0	COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2VH6V@28216|Betaproteobacteria,4A9WU@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS3_k127_1379298_5	365046.Rta_29210	8.824e-18	90.0	2EHXM@1|root,33BP4@2|Bacteria,1NGZB@1224|Proteobacteria,2VXZQ@28216|Betaproteobacteria,4AG52@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3606)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3606
ZZS3_k127_1379298_3	365046.Rta_34560	3.464e-54	195.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSKZ@28216|Betaproteobacteria,4ADX0@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM peptidylprolyl isomerase FKBP-type	fkpA	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
ZZS3_k127_1379298_1	1205680.CAKO01000038_gene1424	8.27e-80	271.0	COG0625@1|root,COG0625@2|Bacteria,1MWUG@1224|Proteobacteria,2TTZ6@28211|Alphaproteobacteria,2JYPD@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_2
ZZS3_k127_1413170_3	543728.Vapar_6328	5.625e-168	545.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,4A9Q8@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_1413170_19	1210908.HSB1_17130	6.127e-17	94.0	COG1881@1|root,arCOG04702@2157|Archaea,2XXMX@28890|Euryarchaeota,23W3N@183963|Halobacteria	183963|Halobacteria	S	COG1881 Phospholipid-binding protein	pebP	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
ZZS3_k127_1413170_15	983917.RGE_04610	6.271e-34	147.0	COG4392@1|root,COG4392@2|Bacteria,1N0X2@1224|Proteobacteria,2VTY9@28216|Betaproteobacteria,1KMAM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM branched-chain amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
ZZS3_k127_1413170_13	864051.BurJ1DRAFT_4293	1.818e-68	241.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,2VPFP@28216|Betaproteobacteria,1KKPF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
ZZS3_k127_1413170_21	1095769.CAHF01000010_gene1179	0.0007193	49.0	2CI80@1|root,308FU@2|Bacteria,1PXE9@1224|Proteobacteria,2WCV3@28216|Betaproteobacteria,4789A@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1413170_14	1121271.AUCM01000004_gene1080	1.995e-66	237.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TZJ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_1413170_11	1504672.669784561	1.674e-86	303.0	COG2372@1|root,COG2372@2|Bacteria,1NZWY@1224|Proteobacteria,2W43X@28216|Betaproteobacteria	28216|Betaproteobacteria	M	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1413170_18	62928.azo1747	2.349e-18	93.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON,LysM
ZZS3_k127_1413170_6	365046.Rta_10200	8.788e-134	441.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2VJE3@28216|Betaproteobacteria,4ABSI@80864|Comamonadaceae	28216|Betaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
ZZS3_k127_1413170_17	365046.Rta_10220	8.96e-21	94.0	COG3729@1|root,COG3729@2|Bacteria,1N69Y@1224|Proteobacteria,2VXCA@28216|Betaproteobacteria,4AJU6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
ZZS3_k127_1413170_2	365046.Rta_10260	2.173e-200	633.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,4ADCP@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_1413170_16	223926.28807892	2.275e-32	134.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,1XV43@135623|Vibrionales	135623|Vibrionales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_1413170_1	365046.Rta_10270	3.307e-207	651.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,4AAEU@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF1508,tRNA-synt_1b
ZZS3_k127_1413170_7	365046.Rta_10280	4.481e-122	395.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,4AC87@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
ZZS3_k127_1413170_10	358220.C380_06435	1.189e-102	336.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,4ACR9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
ZZS3_k127_1413170_9	365046.Rta_10300	1.053e-118	400.0	COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2VKMQ@28216|Betaproteobacteria,4ACBS@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Permeases of the drug metabolite transporter	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
ZZS3_k127_1413170_4	365046.Rta_10310	1.107e-151	482.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,4AB7D@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART phosphoesterase PHP domain protein	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
ZZS3_k127_1413170_12	365046.Rta_10320	2.504e-84	284.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2VM2U@28216|Betaproteobacteria,4AD3M@80864|Comamonadaceae	28216|Betaproteobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
ZZS3_k127_1413170_5	365046.Rta_10330	1.798e-141	460.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,4AA6V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
ZZS3_k127_1413170_0	365046.Rta_10340	2.498e-249	775.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4AA1A@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
ZZS3_k127_1413170_8	614083.AWQR01000043_gene3538	8.812e-122	396.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,4AB5I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
ZZS3_k127_1419792_5	535289.Dtpsy_2658	2.033e-112	367.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VP73@28216|Betaproteobacteria,4AD3G@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	ugpA_1	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K17242,ko:K17245	ko02010,map02010	M00196,M00198,M00207,M00600,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.3,3.A.1.1.39,3.A.1.1.40	-	-	BPD_transp_1
ZZS3_k127_1419792_2	1123504.JQKD01000029_gene4168	6.259e-219	717.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2VJ10@28216|Betaproteobacteria,4AADN@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K05813,ko:K17244	ko02010,map02010	M00198,M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3,3.A.1.1.40	-	-	SBP_bac_8
ZZS3_k127_1419792_4	1219031.BBJR01000028_gene193	2.993e-148	488.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VN9D@28216|Betaproteobacteria,4AD5C@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.20	ko:K05816	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.3	-	-	ABC_tran,TOBE_2
ZZS3_k127_1419792_9	1000565.METUNv1_03706	5.088e-57	212.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,2KVZH@206389|Rhodocyclales	206389|Rhodocyclales	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS3_k127_1419792_8	1402135.SUH3_09070	3.138e-76	260.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,3ZX5J@60136|Sulfitobacter	28211|Alphaproteobacteria	O	This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
ZZS3_k127_1419792_6	698761.RTCIAT899_CH04865	4.418e-84	302.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,4B9SN@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
ZZS3_k127_1419792_1	1123255.JHYS01000022_gene1478	5.204e-222	695.0	COG0477@1|root,COG0477@2|Bacteria,1MVZG@1224|Proteobacteria,2VHUI@28216|Betaproteobacteria,4AB3H@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	TIGRFAM metabolite H symporter, major facilitator superfamily (MFS)	kgtP	-	-	ko:K02625,ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2,2.A.1.6.3	-	-	MFS_1,Sugar_tr
ZZS3_k127_1419792_7	452662.SJA_C1-15650	4.289e-81	296.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2TR4Z@28211|Alphaproteobacteria,2K1XE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the WrbA family	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
ZZS3_k127_1419792_3	1157708.KB907450_gene5558	6.541e-156	501.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VHW3@28216|Betaproteobacteria,4AA9A@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	bepF	-	-	ko:K18901	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_1419792_0	748247.AZKH_2578	0.0	1133.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KUC8@206389|Rhodocyclales	206389|Rhodocyclales	V	Protein export membrane protein	-	-	-	ko:K18902	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_1530582_1	864051.BurJ1DRAFT_1682	1.378e-175	554.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
ZZS3_k127_1530582_2	365046.Rta_34910	2.793e-130	421.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,4A9NX@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS3_k127_1530582_3	365046.Rta_34920	1.23e-123	408.0	COG0664@1|root,COG0664@2|Bacteria,1MUHT@1224|Proteobacteria,2VI43@28216|Betaproteobacteria,4ACD6@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_1530582_0	365046.Rta_34930	0.0	1123.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,4AC0U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
ZZS3_k127_155392_7	44060.JODL01000007_gene1235	1.569e-15	78.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	mcr	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_155392_6	1007105.PT7_0663	6.356e-34	141.0	COG3090@1|root,COG3090@2|Bacteria,1NGAA@1224|Proteobacteria,2W627@28216|Betaproteobacteria,3T7U4@506|Alcaligenaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_155392_0	1007105.PT7_0664	4.417e-182	591.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,3T78K@506|Alcaligenaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_155392_3	1007105.PT7_0665	8.384e-104	348.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,3T69K@506|Alcaligenaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_155392_1	477184.KYC_26837	1.735e-162	537.0	COG1960@1|root,COG1960@2|Bacteria,1MW0F@1224|Proteobacteria,2VH0B@28216|Betaproteobacteria,3T2AQ@506|Alcaligenaceae	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_155392_5	1366050.N234_07335	1.623e-73	273.0	COG1960@1|root,COG1960@2|Bacteria,1NQAE@1224|Proteobacteria,2VIKJ@28216|Betaproteobacteria,1K7QI@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
ZZS3_k127_155392_2	257310.BB0750	1.943e-109	365.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2VJSH@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase	echA8_4	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_155392_4	1265502.KB905932_gene1903	2.108e-82	288.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
ZZS3_k127_1572480_16	1223521.BBJX01000019_gene612	8.383e-61	223.0	COG1664@1|root,COG1664@2|Bacteria,1NBUN@1224|Proteobacteria	1224|Proteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1572480_18	1157708.KB907462_gene875	4.276e-46	175.0	COG0716@1|root,COG0716@2|Bacteria,1NANK@1224|Proteobacteria,2VW78@28216|Betaproteobacteria,4AHHR@80864|Comamonadaceae	28216|Betaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
ZZS3_k127_1572480_5	365046.Rta_16960	2.106e-187	595.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_1572480_23	365044.Pnap_0821	2.29e-17	92.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,4AHJK@80864|Comamonadaceae	28216|Betaproteobacteria	J	'Cold-shock' DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
ZZS3_k127_1572480_2	365044.Pnap_0389	3.17e-245	769.0	COG0459@1|root,COG0459@2|Bacteria,1NRHG@1224|Proteobacteria,2W0NW@28216|Betaproteobacteria,4AH8I@80864|Comamonadaceae	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	-	-	-	-	-	-	-	-	-	Cpn60_TCP1
ZZS3_k127_1572480_20	296591.Bpro_3367	1.836e-33	135.0	COG5622@1|root,COG5622@2|Bacteria,1PUPP@1224|Proteobacteria,2WAVQ@28216|Betaproteobacteria,4AFZU@80864|Comamonadaceae	28216|Betaproteobacteria	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
ZZS3_k127_1572480_7	296591.Bpro_1195	8.189e-181	578.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,4AA57@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
ZZS3_k127_1572480_21	1123504.JQKD01000034_gene2746	5.435e-19	88.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,4AG0G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1572480_24	1276756.AUEX01000015_gene2018	2.207e-05	51.0	2DTS6@1|root,33MFJ@2|Bacteria,1NND1@1224|Proteobacteria,2VYDG@28216|Betaproteobacteria,4AHPF@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1572480_4	314345.SPV1_10656	3.873e-194	620.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria	1224|Proteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
ZZS3_k127_1572480_13	1157708.KB907462_gene912	2.044e-96	325.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2WEGN@28216|Betaproteobacteria,4AEQ1@80864|Comamonadaceae	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
ZZS3_k127_1572480_8	1157708.KB907462_gene913	1.191e-155	522.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2VHS2@28216|Betaproteobacteria,4AG6A@80864|Comamonadaceae	28216|Betaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
ZZS3_k127_1572480_11	1157708.KB907462_gene914	1.659e-108	371.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VMY1@28216|Betaproteobacteria,4AGPA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
ZZS3_k127_1572480_17	296591.Bpro_4847	4.35e-55	208.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2VT72@28216|Betaproteobacteria,4AED9@80864|Comamonadaceae	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
ZZS3_k127_1572480_15	296591.Bpro_4846	1.682e-65	226.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2VSDD@28216|Betaproteobacteria,4AEJS@80864|Comamonadaceae	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
ZZS3_k127_1572480_19	1157708.KB907462_gene908	1.251e-41	155.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,4AFCC@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, ArsR	bigR	-	-	-	-	-	-	-	-	-	-	-	HTH_5
ZZS3_k127_1572480_10	1504672.669785523	1.321e-143	460.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,4ABHP@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	baeB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_1572480_6	1265502.KB905951_gene851	1.222e-182	588.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,4AAM2@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ZZS3_k127_1572480_22	264198.Reut_A0231	5.882e-19	88.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,1KAF4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
ZZS3_k127_1572480_0	365044.Pnap_1249	0.0	1095.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9PT@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
ZZS3_k127_1572480_12	987059.RBXJA2T_06005	2.756e-98	361.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2VMK4@28216|Betaproteobacteria,1KKKP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
ZZS3_k127_1572480_14	296591.Bpro_1187	3.142e-93	312.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,2VU6P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1572480_3	296591.Bpro_1188	1.452e-206	662.0	COG0247@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,1MUMH@1224|Proteobacteria,2WBZQ@28216|Betaproteobacteria,4AIM6@80864|Comamonadaceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,Fer4_8
ZZS3_k127_1572480_9	365044.Pnap_2304	1.908e-148	479.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,4ADVF@80864|Comamonadaceae	28216|Betaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
ZZS3_k127_1572480_1	365044.Pnap_2303	1.346e-248	777.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,4ACQA@80864|Comamonadaceae	28216|Betaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_1645756_3	365046.Rta_08100	1.819e-92	306.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,4ABRN@80864|Comamonadaceae	28216|Betaproteobacteria	E	glutamate synthase, alpha subunit domain protein	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
ZZS3_k127_1645756_0	365046.Rta_08110	5.555e-304	934.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,4A9SB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
ZZS3_k127_1645756_1	365046.Rta_08120	6.252e-135	434.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,4A9UN@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM ABC transporter related	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS3_k127_1645756_2	358220.C380_04345	5.666e-129	428.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,4A9P4@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Permease MlaE	ttg2B	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS3_k127_1645756_5	543728.Vapar_1156	3.879e-79	266.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,4ADFP@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS3_k127_1645756_4	365046.Rta_08150	1.47e-80	282.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,4ADJ3@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
ZZS3_k127_1645756_6	365046.Rta_08160	7.461e-72	245.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,4ACMY@80864|Comamonadaceae	28216|Betaproteobacteria	Q	toluene tolerance family protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
ZZS3_k127_1665465_5	614083.AWQR01000005_gene1152	1.331e-106	354.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,2VI48@28216|Betaproteobacteria,4AD28@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Ion transport protein	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
ZZS3_k127_1665465_8	365046.Rta_13460	2.963e-27	113.0	2END2@1|root,33G0J@2|Bacteria,1NIFI@1224|Proteobacteria,2VVU7@28216|Betaproteobacteria,4AIVD@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1665465_6	1221522.B723_12280	2.049e-53	191.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,1S9MZ@1236|Gammaproteobacteria,1YTM1@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
ZZS3_k127_1665465_9	342113.DM82_1758	1.375e-25	108.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
ZZS3_k127_1665465_2	365046.Rta_11930	3.875e-164	521.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,4ABP9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Luciferase family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
ZZS3_k127_1665465_0	365046.Rta_02490	2.008e-197	619.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2VI04@28216|Betaproteobacteria,4AASZ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
ZZS3_k127_1665465_10	232721.Ajs_1927	9.689e-17	89.0	2ATZM@1|root,31JJE@2|Bacteria,1RIFX@1224|Proteobacteria,2VSS3@28216|Betaproteobacteria,4AF4U@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1665465_1	365046.Rta_11980	5.247e-193	611.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4AB40@80864|Comamonadaceae	28216|Betaproteobacteria	S	DinB superfamily	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
ZZS3_k127_1665465_3	365046.Rta_11990	1.029e-138	467.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,4AB1Q@80864|Comamonadaceae	28216|Betaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
ZZS3_k127_1665465_7	1123504.JQKD01000007_gene3397	9.307e-45	181.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,2VU8K@28216|Betaproteobacteria,4AEWH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
ZZS3_k127_1665465_4	448385.sce1544	5.283e-112	363.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,43853@68525|delta/epsilon subdivisions,2X3F2@28221|Deltaproteobacteria,2YVSZ@29|Myxococcales	28221|Deltaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
ZZS3_k127_1716697_1	595537.Varpa_1501	9.106e-262	812.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,4AB9Q@80864|Comamonadaceae	28216|Betaproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
ZZS3_k127_1716697_4	365046.Rta_28760	1.899e-146	473.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,4AA12@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase internal region	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
ZZS3_k127_1716697_7	365044.Pnap_3096	1.289e-105	347.0	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,2VPZX@28216|Betaproteobacteria,4AA5R@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM response regulator receiver	algR	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
ZZS3_k127_1716697_3	365046.Rta_28740	3.133e-154	509.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2VHC0@28216|Betaproteobacteria,4AC17@80864|Comamonadaceae	28216|Betaproteobacteria	T	Gaf domain protein	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport,GAF_2
ZZS3_k127_1716697_10	1157708.KB907450_gene5236	1.024e-35	153.0	2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2VUAQ@28216|Betaproteobacteria,4AEUG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
ZZS3_k127_1716697_0	365046.Rta_28690	0.0	1508.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,4A9YM@80864|Comamonadaceae	28216|Betaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
ZZS3_k127_1716697_5	365046.Rta_28680	1.288e-138	451.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,4ABY8@80864|Comamonadaceae	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
ZZS3_k127_1716697_8	365046.Rta_28670	2.207e-73	261.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,4ADM1@80864|Comamonadaceae	28216|Betaproteobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
ZZS3_k127_1716697_6	365046.Rta_28660	4.413e-111	381.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,4AARN@80864|Comamonadaceae	28216|Betaproteobacteria	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,HemX
ZZS3_k127_1716697_2	365046.Rta_28650	6.687e-177	565.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,4A9SX@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM HemY domain protein	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_12
ZZS3_k127_1716697_9	1268622.AVS7_02181	2.844e-37	156.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,4ABMR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
ZZS3_k127_1731235_0	614083.AWQR01000013_gene1706	0.0	1034.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,4A9RV@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	iorB2	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
ZZS3_k127_1731235_3	296591.Bpro_4228	4.7e-76	259.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VRRI@28216|Betaproteobacteria,4ADXG@80864|Comamonadaceae	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
ZZS3_k127_1731235_1	1123504.JQKD01000041_gene2826	4.972e-285	893.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,4AA2X@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC transporter related	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
ZZS3_k127_1731235_2	365046.Rta_05430	7.637e-228	718.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,4A9J8@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_1731235_4	365046.Rta_05420	3.175e-34	131.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VH8F@28216|Betaproteobacteria,4ACD0@80864|Comamonadaceae	28216|Betaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
ZZS3_k127_1744394_0	1157708.KB907469_gene16	0.0	1099.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VN0R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
ZZS3_k127_1744394_2	1286631.X805_25030	8.646e-54	216.0	COG1522@1|root,COG1522@2|Bacteria,1RJ7F@1224|Proteobacteria,2VTCR@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
ZZS3_k127_1744394_1	543728.Vapar_2005	7.429e-117	381.0	COG1073@1|root,COG1073@2|Bacteria,1NXZW@1224|Proteobacteria,2VNFH@28216|Betaproteobacteria,4AGAU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4,Peptidase_S9
ZZS3_k127_1744394_3	420324.KI912044_gene3962	2.608e-21	94.0	28HHS@1|root,2Z7TD@2|Bacteria,1R7VF@1224|Proteobacteria,2U1A8@28211|Alphaproteobacteria,1JR3C@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3182
ZZS3_k127_1769857_0	365046.Rta_22350	1.034e-200	626.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VIK5@28216|Betaproteobacteria,4ABK8@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_1769857_2	1100720.ALKN01000026_gene1668	1.082e-153	488.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,4AB0U@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_1769857_1	365046.Rta_22370	1.392e-168	544.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VK9Y@28216|Betaproteobacteria,4AA2K@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_1769857_4	296591.Bpro_2988	3.604e-122	399.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VKUM@28216|Betaproteobacteria,4ABGV@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_1769857_3	365046.Rta_22390	2.695e-126	407.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2VHGT@28216|Betaproteobacteria,4ACSD@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_1769857_5	1123504.JQKD01000003_gene568	1.911e-92	312.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria,4ACF1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
ZZS3_k127_1805019_4	398578.Daci_3787	8.576e-30	119.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2VIDP@28216|Betaproteobacteria,4ACKP@80864|Comamonadaceae	28216|Betaproteobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,META
ZZS3_k127_1805019_2	228410.NE0294	7.352e-221	737.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,2VIUK@28216|Betaproteobacteria,37425@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
ZZS3_k127_1805019_0	365046.Rta_24250	0.0	1052.0	COG4773@1|root,COG4773@2|Bacteria,1NZCG@1224|Proteobacteria,2WGJU@28216|Betaproteobacteria,4AJZI@80864|Comamonadaceae	28216|Betaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
ZZS3_k127_1805019_3	543728.Vapar_5168	1.169e-125	413.0	COG3182@1|root,COG3182@2|Bacteria,1MXGY@1224|Proteobacteria,2VKWA@28216|Betaproteobacteria,4ADVP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pepsy-associated tm helix	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_TM
ZZS3_k127_1805019_1	395495.Lcho_3847	4.205e-298	921.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,1KIZA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
ZZS3_k127_1805019_6	395495.Lcho_3846	2.814e-18	85.0	2EJUE@1|root,33DJ2@2|Bacteria,1NJVX@1224|Proteobacteria,2VY2W@28216|Betaproteobacteria,1KMQ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1805019_5	397945.Aave_2642	2.606e-22	96.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,4AB98@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
ZZS3_k127_1828483_0	365046.Rta_09890	8.066e-221	692.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,4A9KA@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Ribonuclease II	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
ZZS3_k127_1828483_1	365046.Rta_09880	1.85e-132	431.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,4AADE@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
ZZS3_k127_1828483_3	596153.Alide_3683	1.661e-106	357.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,4ACKF@80864|Comamonadaceae	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
ZZS3_k127_1828483_2	365046.Rta_09860	4.584e-108	368.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,4AA9U@80864|Comamonadaceae	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
ZZS3_k127_1828483_4	365046.Rta_09800	4.372e-86	289.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,4ABV5@80864|Comamonadaceae	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
ZZS3_k127_1833494_2	365046.Rta_17530	5.052e-153	489.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,4AAK8@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
ZZS3_k127_1833494_9	296591.Bpro_2684	6.362e-65	240.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,4ADIB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
ZZS3_k127_1833494_3	358220.C380_09160	2.986e-127	411.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,4AB4E@80864|Comamonadaceae	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
ZZS3_k127_1833494_1	887062.HGR_12777	6.648e-157	503.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,4A9M3@80864|Comamonadaceae	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
ZZS3_k127_1833494_6	365046.Rta_17570	5.389e-95	319.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,4AAT9@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
ZZS3_k127_1833494_4	596154.Alide2_3455	3.038e-106	360.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,4AAP3@80864|Comamonadaceae	28216|Betaproteobacteria	J	tRNA rRNA methyltransferase, SpoU	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
ZZS3_k127_1833494_8	861299.J421_6171	2.137e-82	288.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_6171|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1833494_5	296591.Bpro_0177	1.087e-96	337.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_1833494_7	1123255.JHYS01000012_gene1365	2.498e-85	306.0	COG3134@1|root,COG3134@2|Bacteria,1MY27@1224|Proteobacteria,2VMUB@28216|Betaproteobacteria,4AD9C@80864|Comamonadaceae	28216|Betaproteobacteria	S	Beta/Gamma crystallin	-	-	-	-	-	-	-	-	-	-	-	-	Crystall,Rick_17kDa_Anti
ZZS3_k127_1833494_10	1458275.AZ34_05150	3.656e-32	139.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUHT@28216|Betaproteobacteria,4AF5X@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
ZZS3_k127_1833494_0	365046.Rta_17590	2.538e-222	695.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,4ABQA@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
ZZS3_k127_1833494_11	1121116.KB894767_gene2222	5.135e-23	99.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,4ABM3@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
ZZS3_k127_1888962_1	296591.Bpro_2804	2.028e-199	625.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,4AB8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
ZZS3_k127_1888962_0	397945.Aave_3829	8.486e-301	930.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,2WHGT@28216|Betaproteobacteria,4AD5I@80864|Comamonadaceae	28216|Betaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_1888962_3	358220.C380_18895	2.094e-119	396.0	COG0583@1|root,COG0583@2|Bacteria,1N4P5@1224|Proteobacteria,2VMWX@28216|Betaproteobacteria,4AAMS@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_1888962_4	864051.BurJ1DRAFT_0174	4.987e-106	365.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,1KJU5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ZZS3_k127_1888962_2	864051.BurJ1DRAFT_0175	1.286e-193	608.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,1KJFJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	cbbA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
ZZS3_k127_1888962_5	395495.Lcho_0355	2.861e-29	117.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,1KJ7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
ZZS3_k127_1893065_4	1268622.AVS7_03357	1.321e-59	214.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VKXG@28216|Betaproteobacteria,4AAWW@80864|Comamonadaceae	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
ZZS3_k127_1893065_0	1156919.QWC_29090	2.189e-140	452.0	COG2207@1|root,COG2207@2|Bacteria,1MY46@1224|Proteobacteria,2VKKU@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
ZZS3_k127_1893065_1	1156919.QWC_29095	1.429e-110	375.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2WI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_1893065_3	1235457.C404_01940	6.822e-100	340.0	COG0583@1|root,COG0583@2|Bacteria,1R5RF@1224|Proteobacteria,2VNQV@28216|Betaproteobacteria,1K9UP@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_1893065_2	1205680.CAKO01000002_gene2465	3.189e-100	334.0	COG1414@1|root,COG1414@2|Bacteria,1RA2W@1224|Proteobacteria,2U0RW@28211|Alphaproteobacteria,2JWRI@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_1893065_5	762376.AXYL_04904	3.246e-55	196.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,3T2CW@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig
ZZS3_k127_1895871_3	1223521.BBJX01000007_gene1560	7.586e-19	100.0	COG0439@1|root,COG4770@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2VJRB@28216|Betaproteobacteria,4ABDE@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
ZZS3_k127_1895871_0	338969.Rfer_3898	9.658e-267	831.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VN4N@28216|Betaproteobacteria,4ABU4@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_1895871_2	358220.C380_02250	1.097e-102	337.0	COG1309@1|root,COG1309@2|Bacteria,1PA7Z@1224|Proteobacteria,2VP5A@28216|Betaproteobacteria,4AA14@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_1895871_1	1380355.JNIJ01000007_gene3237	1.314e-137	470.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,3K6MI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
ZZS3_k127_193839_1	1268622.AVS7_03929	1.579e-180	569.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,4AA48@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS3_k127_193839_2	365046.Rta_18610	7.459e-119	390.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,4AC1S@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
ZZS3_k127_193839_4	1223521.BBJX01000004_gene2336	9.801e-58	215.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,4ADKN@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
ZZS3_k127_193839_0	365046.Rta_18630	0.0	1162.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,4AAI1@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
ZZS3_k127_193839_3	1123504.JQKD01000031_gene4531	1.289e-107	349.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,4AAPJ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
ZZS3_k127_1959820_12	1265502.KB905929_gene2216	5.847e-46	170.0	COG2453@1|root,COG2453@2|Bacteria,1NDVQ@1224|Proteobacteria,2VWYX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
ZZS3_k127_1959820_1	365046.Rta_27710	2.261e-172	564.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2VH58@28216|Betaproteobacteria,4AB0M@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_1959820_7	365046.Rta_27700	1.319e-92	310.0	COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,2VQDM@28216|Betaproteobacteria,4ACPF@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_1959820_14	1538295.JY96_15105	1.238e-23	105.0	COG1018@1|root,COG1018@2|Bacteria,1N8XZ@1224|Proteobacteria,2VVY7@28216|Betaproteobacteria,1KMJS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
ZZS3_k127_1959820_4	365046.Rta_27680	5.306e-122	406.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,4A9WM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
ZZS3_k127_1959820_8	365046.Rta_27660	2.414e-74	263.0	COG1376@1|root,COG1376@2|Bacteria,1R7VK@1224|Proteobacteria,2VRX0@28216|Betaproteobacteria,4AE5A@80864|Comamonadaceae	28216|Betaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1959820_10	365046.Rta_27650	8.02e-61	217.0	COG1376@1|root,COG1376@2|Bacteria,1NVQI@1224|Proteobacteria,2W2SC@28216|Betaproteobacteria,4AHXR@80864|Comamonadaceae	28216|Betaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1959820_15	365044.Pnap_1306	3.284e-21	100.0	2D78S@1|root,32TNJ@2|Bacteria,1N0VB@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4864)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864
ZZS3_k127_1959820_5	365044.Pnap_2699	2.284e-95	320.0	COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,2VMFZ@28216|Betaproteobacteria,4ACYZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1959820_2	864051.BurJ1DRAFT_0006	5.022e-155	497.0	COG1680@1|root,COG1680@2|Bacteria,1PGX2@1224|Proteobacteria,2W9MK@28216|Betaproteobacteria,1KP1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_1959820_9	748280.NH8B_0126	3.69e-68	243.0	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_17
ZZS3_k127_1959820_16	62928.azo0532	1.359e-10	67.0	2BTVK@1|root,32P3F@2|Bacteria,1Q7K1@1224|Proteobacteria,2VZ2P@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1959820_3	1223521.BBJX01000014_gene326	5.524e-147	473.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,4ACMK@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS3_k127_1959820_13	365046.Rta_27610	4.456e-38	146.0	COG1544@1|root,COG1544@2|Bacteria,1N9T3@1224|Proteobacteria,2VV1N@28216|Betaproteobacteria,4AF4D@80864|Comamonadaceae	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
ZZS3_k127_1959820_6	1504672.669783262	5.093e-95	318.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,4ABJT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
ZZS3_k127_1959820_0	365046.Rta_18760	1.083e-307	948.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2VKCH@28216|Betaproteobacteria,4A9VW@80864|Comamonadaceae	28216|Betaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
ZZS3_k127_1959820_11	420662.Mpe_A2179	1.183e-59	214.0	COG1653@1|root,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,2VUUT@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
ZZS3_k127_197599_21	395019.Bmul_5356	5.648e-16	79.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria,1K43E@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
ZZS3_k127_197599_16	339670.Bamb_1612	5.068e-64	223.0	COG1764@1|root,COG1764@2|Bacteria,1RD92@1224|Proteobacteria,2W2KB@28216|Betaproteobacteria,1K7PK@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS3_k127_197599_5	1458275.AZ34_17135	9.427e-136	443.0	COG0477@1|root,COG0477@2|Bacteria,1QU73@1224|Proteobacteria,2WGWQ@28216|Betaproteobacteria,4AC2Z@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_197599_9	381666.H16_B1790	4.533e-100	335.0	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,2VJFQ@28216|Betaproteobacteria,1K4CZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
ZZS3_k127_197599_18	1157708.KB907456_gene2236	3.263e-30	129.0	COG1247@1|root,COG1247@2|Bacteria,1QVS0@1224|Proteobacteria,2W2KH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS3_k127_197599_19	381666.H16_A1662	1.109e-18	95.0	COG4568@1|root,COG4568@2|Bacteria,1NKDC@1224|Proteobacteria,2W48P@28216|Betaproteobacteria,1KEK0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	rho-dependent transcription termination	-	-	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	-
ZZS3_k127_197599_3	1366050.N234_28175	6.905e-186	611.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VHCF@28216|Betaproteobacteria,1K6E3@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Amidase	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
ZZS3_k127_197599_4	1366050.N234_30720	2.775e-174	577.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2W1R8@28216|Betaproteobacteria,1KGRA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
ZZS3_k127_197599_22	1003200.AXXA_23390	4.218e-07	60.0	2C3D2@1|root,33DT8@2|Bacteria,1NIIF@1224|Proteobacteria,2VXZZ@28216|Betaproteobacteria,3T8HA@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4148
ZZS3_k127_197599_1	196367.JNFG01000008_gene6553	2.749e-206	663.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KGEM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
ZZS3_k127_197599_10	543728.Vapar_0142	4.834e-99	344.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,4AAIW@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_197599_17	931626.Awo_c21070	3.736e-36	151.0	COG5434@1|root,COG5434@2|Bacteria,1TSQD@1239|Firmicutes,249Z8@186801|Clostridia	186801|Clostridia	MQ	Cell wall-binding repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,Pectate_lyase_3
ZZS3_k127_197599_7	296591.Bpro_4285	1.189e-104	351.0	COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,2VHXD@28216|Betaproteobacteria,4ABRM@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	ko:K21699	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_197599_0	1219031.BBJR01000050_gene1638	6.977e-216	678.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,4AAEX@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_197599_8	1235457.C404_11520	3.738e-101	345.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2VMHY@28216|Betaproteobacteria,1K10M@119060|Burkholderiaceae	28216|Betaproteobacteria	K	periplasmic binding protein LacI transcriptional regulator	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ZZS3_k127_197599_6	1123023.JIAI01000001_gene7514	3.693e-134	444.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
ZZS3_k127_197599_11	1123023.JIAI01000004_gene7872	4.362e-97	332.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4E02S@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_197599_13	1123023.JIAI01000001_gene7513	2.135e-82	297.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_197599_2	1123023.JIAI01000001_gene7512	4.113e-197	651.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4DXTR@85010|Pseudonocardiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
ZZS3_k127_197599_14	1317118.ATO8_17185	1.063e-79	287.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,4KNJY@93682|Roseivivax	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
ZZS3_k127_197599_12	1123023.JIAI01000001_gene7510	9.612e-90	313.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4E02S@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_197599_15	1502850.FG91_00774	7.608e-75	277.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TU9F@28211|Alphaproteobacteria,2K3X4@204457|Sphingomonadales	204457|Sphingomonadales	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_1978643_6	365046.Rta_11560	2.297e-168	538.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4AAAX@80864|Comamonadaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
ZZS3_k127_1978643_10	84531.JMTZ01000068_gene1768	7.713e-57	206.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1S39N@1236|Gammaproteobacteria,1XBYC@135614|Xanthomonadales	135614|Xanthomonadales	GM	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
ZZS3_k127_1978643_0	365046.Rta_14460	0.0	1134.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2VK2V@28216|Betaproteobacteria,4ABET@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS3_k127_1978643_1	1100720.ALKN01000044_gene2068	6.626e-238	741.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2VK04@28216|Betaproteobacteria,4AC9Z@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_1978643_11	227086.JGI_V11_134829	1.868e-12	77.0	2DPTS@1|root,2S6A9@2759|Eukaryota	2759|Eukaryota	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ZZS3_k127_1978643_4	365046.Rta_11530	4.237e-176	580.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,4ABPX@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
ZZS3_k127_1978643_2	365046.Rta_11520	2.054e-233	728.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4A9YS@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K21393	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctM
ZZS3_k127_1978643_9	365046.Rta_11510	7.927e-81	272.0	COG3090@1|root,COG3090@2|Bacteria,1RIQN@1224|Proteobacteria,2VQST@28216|Betaproteobacteria,4ADJB@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	ko:K21394	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctQ
ZZS3_k127_1978643_8	365046.Rta_11500	1.371e-126	408.0	COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,2VHMI@28216|Betaproteobacteria,4AB8D@80864|Comamonadaceae	28216|Betaproteobacteria	K	regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_1978643_5	1095769.CAHF01000007_gene1662	1.094e-169	539.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
ZZS3_k127_1978643_3	595537.Varpa_5385	1.556e-212	687.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VJYY@28216|Betaproteobacteria,4ACCN@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
ZZS3_k127_1978643_7	864051.BurJ1DRAFT_0686	1.805e-167	529.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2VHA0@28216|Betaproteobacteria,1KKBG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
ZZS3_k127_1990912_10	1038862.KB893906_gene5423	2.734e-57	203.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,3JW29@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	MA20_06335	-	4.2.1.156,4.2.1.42,5.1.2.2	ko:K01781,ko:K20023	ko00053,ko00627,ko01120,map00053,map00627,map01120	-	R03791,R04161,R05608	RC00543,RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_1990912_11	1095769.CAHF01000019_gene864	7.891e-25	109.0	2EIEB@1|root,33C5R@2|Bacteria,1NNGW@1224|Proteobacteria,2VXW2@28216|Betaproteobacteria,474Y2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PXPV repeat (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	PXPV
ZZS3_k127_1990912_8	1123060.JONP01000006_gene4838	2.983e-73	265.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2JPN0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ZZS3_k127_1990912_1	365046.Rta_24740	1.52e-176	557.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,4AA26@80864|Comamonadaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_1990912_9	1097668.BYI23_C007560	2.299e-61	233.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,1K8YH@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_1990912_5	1205680.CAKO01000008_gene4097	8.882e-98	331.0	COG1840@1|root,COG1840@2|Bacteria,1R9BH@1224|Proteobacteria,2TQP7@28211|Alphaproteobacteria,2JVR7@204441|Rhodospirillales	204441|Rhodospirillales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
ZZS3_k127_1990912_0	1205680.CAKO01000008_gene4098	9.787e-209	663.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,2JVYX@204441|Rhodospirillales	204441|Rhodospirillales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ZZS3_k127_1990912_4	935840.JAEQ01000020_gene2341	1.435e-134	437.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,43HYB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	TOBE domain	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
ZZS3_k127_1990912_3	1382304.JNIL01000001_gene1394	5.892e-154	496.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes	1239|Firmicutes	C	carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_1990912_6	666684.AfiDRAFT_3816	2.056e-97	338.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3JRS0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS3_k127_1990912_7	1100720.ALKN01000040_gene2174	7.276e-94	316.0	COG0697@1|root,COG0697@2|Bacteria,1MY2U@1224|Proteobacteria,2VWY7@28216|Betaproteobacteria,4AHIY@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_1990912_2	595537.Varpa_1705	9.606e-174	556.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2VM19@28216|Betaproteobacteria,4ABT0@80864|Comamonadaceae	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_1990912_12	365046.Rta_24730	7.393e-13	81.0	COG3495@1|root,COG3495@2|Bacteria,1NE6B@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3299
ZZS3_k127_2003673_2	296591.Bpro_2850	9.089e-229	713.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,4AC58@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_2003673_26	1157708.KB907450_gene5214	1.011e-06	57.0	2CST2@1|root,32SRU@2|Bacteria,1N2M8@1224|Proteobacteria,2VUU3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2003673_8	365046.Rta_23650	4.854e-149	478.0	COG2866@1|root,COG2866@2|Bacteria,1NW73@1224|Proteobacteria,2VJH0@28216|Betaproteobacteria,4AA99@80864|Comamonadaceae	28216|Betaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS3_k127_2003673_20	365046.Rta_23640	1.883e-59	227.0	COG2267@1|root,COG2267@2|Bacteria,1RBM5@1224|Proteobacteria,2VR22@28216|Betaproteobacteria,4AETM@80864|Comamonadaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
ZZS3_k127_2003673_22	1157708.KB907453_gene4247	6.862e-40	150.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,4AEZN@80864|Comamonadaceae	28216|Betaproteobacteria	K	SMART regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
ZZS3_k127_2003673_17	402626.Rpic_3827	1.488e-76	258.0	COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2VQPS@28216|Betaproteobacteria,1KH9U@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	cadI	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
ZZS3_k127_2003673_18	1235457.C404_18190	6.04e-76	278.0	COG0394@1|root,COG0394@2|Bacteria,1MVGB@1224|Proteobacteria,2WEYH@28216|Betaproteobacteria,1KHX5@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
ZZS3_k127_2003673_16	859657.RPSI07_mp0925	4.374e-106	349.0	COG0580@1|root,COG0580@2|Bacteria,1PPX1@1224|Proteobacteria,2VRTJ@28216|Betaproteobacteria,1KGXP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	-	-	-	-	-	-	-	-	-	MIP
ZZS3_k127_2003673_13	365046.Rta_23630	4.082e-138	443.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,4AAW7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Ornithine-acyl acyl carrier protein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
ZZS3_k127_2003673_11	296591.Bpro_2244	2.179e-144	473.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2VHU3@28216|Betaproteobacteria,4ACS8@80864|Comamonadaceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_2003673_4	365046.Rta_26190	1.632e-155	513.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,4AB0Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	gtrA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2003673_0	365046.Rta_23620	0.0	1065.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,4A9NH@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
ZZS3_k127_2003673_19	365044.Pnap_2211	3.998e-63	221.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,4ADWN@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
ZZS3_k127_2003673_25	296591.Bpro_2248	2.274e-24	107.0	2E4XE@1|root,32ZRB@2|Bacteria,1N7HI@1224|Proteobacteria,2VVPN@28216|Betaproteobacteria,4AFII@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2003673_1	365046.Rta_23550	1.339e-237	745.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,4AC4P@80864|Comamonadaceae	28216|Betaproteobacteria	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
ZZS3_k127_2003673_10	1121035.AUCH01000003_gene1350	9.088e-148	495.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KY34@206389|Rhodocyclales	206389|Rhodocyclales	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hpt,PilJ
ZZS3_k127_2003673_24	1121035.AUCH01000003_gene1351	2.387e-29	136.0	COG2201@1|root,COG2201@2|Bacteria,1N3V6@1224|Proteobacteria,2VSF3@28216|Betaproteobacteria,2KZ0X@206389|Rhodocyclales	206389|Rhodocyclales	NT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ZZS3_k127_2003673_23	748247.AZKH_2573	4.179e-35	145.0	COG1406@1|root,COG1406@2|Bacteria,1R99A@1224|Proteobacteria,2VMW9@28216|Betaproteobacteria,2KYYJ@206389|Rhodocyclales	206389|Rhodocyclales	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
ZZS3_k127_2003673_5	395495.Lcho_1654	8.117e-155	502.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2VKAU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
ZZS3_k127_2003673_7	395495.Lcho_1655	4.47e-150	481.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KNKG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS3_k127_2003673_12	395495.Lcho_1656	4.597e-141	485.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,1KNU3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ZZS3_k127_2003673_9	395495.Lcho_1657	1.134e-148	473.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KK41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS3_k127_2003673_15	296591.Bpro_2256	6.041e-107	364.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,4AB37@80864|Comamonadaceae	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
ZZS3_k127_2003673_14	365046.Rta_23480	8.773e-122	396.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,4A9UT@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_2003673_6	358220.C380_09305	9.562e-155	502.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,4A9K8@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
ZZS3_k127_2003673_3	543728.Vapar_2318	2.651e-176	571.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria,4AAJJ@80864|Comamonadaceae	28216|Betaproteobacteria	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
ZZS3_k127_2003673_21	365046.Rta_23460	1.141e-53	192.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,4A9MR@80864|Comamonadaceae	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	arnT	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2013766_14	380358.XALC_2306	2.756e-54	190.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1X34S@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS3_k127_2013766_17	1300345.LF41_1466	5.394e-21	99.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,1SGAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,EF-hand_6,EF-hand_7,EF-hand_8
ZZS3_k127_2013766_5	365046.Rta_22550	1.122e-145	466.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2VIEZ@28216|Betaproteobacteria,4ABBT@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
ZZS3_k127_2013766_3	338969.Rfer_0184	5.541e-163	521.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,2VJKI@28216|Betaproteobacteria,4A9YZ@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
ZZS3_k127_2013766_4	365046.Rta_22530	3.345e-147	472.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2VI8W@28216|Betaproteobacteria,4ABGX@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate ABC transporter, inner membrane subunit	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ZZS3_k127_2013766_12	365046.Rta_22520	2.886e-62	231.0	COG4341@1|root,COG4341@2|Bacteria,1N0MY@1224|Proteobacteria,2VRAB@28216|Betaproteobacteria,4ADQP@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM phosphonate degradation operons associated HDIG domain protein	-	-	1.13.11.78	ko:K21196	ko00440,map00440	-	R10722	RC03261	ko00000,ko00001,ko01000	-	-	-	HD
ZZS3_k127_2013766_15	365046.Rta_22515	1.048e-53	203.0	COG0454@1|root,COG0456@2|Bacteria,1PFFT@1224|Proteobacteria,2WC3B@28216|Betaproteobacteria,4AISV@80864|Comamonadaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_2013766_13	365046.Rta_22510	2.861e-61	230.0	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,2VSGN@28216|Betaproteobacteria,4AFFR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)	phnN	-	2.4.2.4,2.7.4.23	ko:K00758,ko:K05774	ko00030,ko00240,ko00983,ko01100,ko05219,map00030,map00240,map00983,map01100,map05219	-	R01570,R02484,R06836,R08222,R08230	RC00002,RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_transf_3,Guanylate_kin,PYNP_C
ZZS3_k127_2013766_10	365046.Rta_22500	4.308e-77	276.0	COG3709@1|root,COG3709@2|Bacteria,1RK3Z@1224|Proteobacteria,2VV9A@28216|Betaproteobacteria,4AJGJ@80864|Comamonadaceae	28216|Betaproteobacteria	P	Protein of unknown function (DUF1045)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1045
ZZS3_k127_2013766_6	365046.Rta_22490	2.869e-116	379.0	COG2188@1|root,COG2188@2|Bacteria,1Q856@1224|Proteobacteria,2VRGG@28216|Betaproteobacteria,4AEKJ@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA	phnF	-	-	ko:K02043	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
ZZS3_k127_2013766_16	365046.Rta_22480	1.804e-47	175.0	COG3624@1|root,COG3624@2|Bacteria,1MZTZ@1224|Proteobacteria,2VV43@28216|Betaproteobacteria,4AFIN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Phosphonate C-P lyase system protein PhnG	phnG	-	2.7.8.37	ko:K06166	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	PhnG
ZZS3_k127_2013766_11	365046.Rta_22470	6.945e-74	260.0	COG3625@1|root,COG3625@2|Bacteria,1RHXN@1224|Proteobacteria,2VU2X@28216|Betaproteobacteria,4AFSK@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate C-P lyase system protein PhnH	phnH	-	2.7.8.37	ko:K06165	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	PhnH
ZZS3_k127_2013766_1	365046.Rta_22460	8.517e-189	602.0	COG3626@1|root,COG3626@2|Bacteria,1MUBA@1224|Proteobacteria,2VJPK@28216|Betaproteobacteria,4AD2A@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate metabolism	phnI	-	2.7.8.37	ko:K06164	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	PhnI
ZZS3_k127_2013766_2	365046.Rta_22450	1.202e-170	539.0	COG3627@1|root,COG3627@2|Bacteria,1MV7T@1224|Proteobacteria,2VIVM@28216|Betaproteobacteria,4ABDI@80864|Comamonadaceae	28216|Betaproteobacteria	P	Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose	phnJ	-	4.7.1.1	ko:K06163	ko00440,map00440	-	R10204	RC03078,RC03079	ko00000,ko00001,ko01000	-	-	-	PhnJ
ZZS3_k127_2013766_8	381666.H16_B1284	2.95e-99	344.0	COG4107@1|root,COG4107@2|Bacteria,1MVRN@1224|Proteobacteria,2VH07@28216|Betaproteobacteria,1K1DS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	phosphonate C-P lyase system protein PhnK	phnK	-	-	ko:K05781	-	-	-	-	ko00000	-	-	-	ABC_tran,oligo_HPY
ZZS3_k127_2013766_7	365046.Rta_22430	2.678e-112	381.0	COG4778@1|root,COG4778@2|Bacteria,1MUPB@1224|Proteobacteria,2VQ6N@28216|Betaproteobacteria,4ADF6@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate C-P lyase system protein PhnL	phnL	-	2.7.8.37	ko:K05780	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	ABC_tran
ZZS3_k127_2013766_0	365046.Rta_22420	9.078e-210	663.0	COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,2VMPU@28216|Betaproteobacteria,4ACTA@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM phosphonate metabolism protein PhnM	phnM	-	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
ZZS3_k127_2013766_9	1157708.KB907451_gene4793	3.619e-77	262.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,4AA74@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
ZZS3_k127_2028760_4	1276756.AUEX01000035_gene2235	2.834e-78	274.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria,4AACJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
ZZS3_k127_2028760_5	296591.Bpro_4049	2.932e-63	221.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,4ADW3@80864|Comamonadaceae	28216|Betaproteobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
ZZS3_k127_2028760_2	365046.Rta_10140	2.082e-218	680.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,4ABVA@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_2028760_3	365046.Rta_10130	4.049e-113	372.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VJ4X@28216|Betaproteobacteria,4AAZ8@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_2028760_1	365046.Rta_10120	0.0	1127.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VJ2Q@28216|Betaproteobacteria,4ACRG@80864|Comamonadaceae	28216|Betaproteobacteria	Q	C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_2028760_0	365046.Rta_10110	0.0	1154.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,4AC69@80864|Comamonadaceae	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
ZZS3_k127_2056459_2	365046.Rta_11650	1.165e-53	190.0	COG1846@1|root,COG1846@2|Bacteria,1RJEE@1224|Proteobacteria,2VSK5@28216|Betaproteobacteria,4AEZ0@80864|Comamonadaceae	28216|Betaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
ZZS3_k127_2056459_0	319003.Bra1253DRAFT_08347	1.283e-179	570.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV3I@28211|Alphaproteobacteria,3JS2U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	1.14.13.229,1.14.19.48	ko:K21323	-	-	-	-	ko00000,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS3_k127_2056459_1	1123504.JQKD01000016_gene1949	1.112e-67	257.0	COG3181@1|root,COG3181@2|Bacteria,1NF9R@1224|Proteobacteria,2VM37@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2056459_3	266835.14024488	1.546e-51	205.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2U0DQ@28211|Alphaproteobacteria,43PTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2056459_4	1348657.M622_00385	6.682e-37	142.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,2KWYD@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS3_k127_2056459_5	269799.Gmet_1707	2.248e-17	91.0	COG0697@1|root,COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0697@2|Bacteria,COG0784@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X7KH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg
ZZS3_k127_2061195_3	365046.Rta_34050	3.533e-165	523.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,4AD65@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
ZZS3_k127_2061195_6	365046.Rta_34060	2.303e-91	326.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,4AB54@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS3_k127_2061195_1	365046.Rta_34070	4.535e-228	728.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,4AA5D@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM amidohydrolase	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
ZZS3_k127_2061195_2	595537.Varpa_5218	9.736e-187	589.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,4ABIN@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS3_k127_2061195_7	1276756.AUEX01000006_gene3096	1.156e-71	254.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,4ADHM@80864|Comamonadaceae	28216|Betaproteobacteria	F	phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
ZZS3_k127_2061195_8	535289.Dtpsy_2895	1.528e-57	213.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,4AE0V@80864|Comamonadaceae	28216|Betaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
ZZS3_k127_2061195_5	365046.Rta_34110	3.922e-99	332.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,4AAUH@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
ZZS3_k127_2061195_4	1123393.KB891316_gene2018	2.35e-121	399.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2061195_0	365046.Rta_34130	0.0	2400.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4ABCW@80864|Comamonadaceae	28216|Betaproteobacteria	T	ATP-binding region, ATPase domain protein	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
ZZS3_k127_2061195_9	365046.Rta_34140	5.267e-36	137.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,4ABIH@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PFAM chemotaxis sensory transducer	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
ZZS3_k127_2063308_3	365044.Pnap_2740	5.569e-106	350.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VIYR@28216|Betaproteobacteria,4ACV9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	-	-	-	ko:K11329	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_2063308_4	358220.C380_13570	9.8e-39	156.0	2DHD4@1|root,32U92@2|Bacteria,1N29H@1224|Proteobacteria,2VU9F@28216|Betaproteobacteria,4AEY8@80864|Comamonadaceae	28216|Betaproteobacteria	S	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
ZZS3_k127_2063308_1	595537.Varpa_4453	1.115e-132	439.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2WF3T@28216|Betaproteobacteria,4AJRA@80864|Comamonadaceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_2063308_2	543728.Vapar_2123	1.453e-116	384.0	COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria,2W220@28216|Betaproteobacteria,4AH36@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K06912	ko00361,ko01120,ko01220,map00361,map01120,map01220	-	R05419,R05493	RC01371,RC01372	ko00000,ko00001,ko01000	-	-	-	TauD
ZZS3_k127_2063308_0	1100720.ALKN01000035_gene989	1.814e-170	540.0	COG3181@1|root,COG3181@2|Bacteria,1NTMU@1224|Proteobacteria,2W1QZ@28216|Betaproteobacteria,4AGAF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2063308_5	762376.AXYL_04331	4.576e-32	129.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2VKXH@28216|Betaproteobacteria,3T4EB@506|Alcaligenaceae	28216|Betaproteobacteria	Q	taurine dioxygenase	tauD	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
ZZS3_k127_2068415_8	614083.AWQR01000044_gene2021	4.388e-21	92.0	COG3618@1|root,COG3618@2|Bacteria,1QWWJ@1224|Proteobacteria,2VMAE@28216|Betaproteobacteria,4AAG5@80864|Comamonadaceae	28216|Betaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS3_k127_2068415_4	365046.Rta_03110	1.11e-99	331.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VQ03@28216|Betaproteobacteria,4AJ93@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
ZZS3_k127_2068415_3	365046.Rta_03140	2.141e-152	490.0	COG0598@1|root,COG0598@2|Bacteria,1NWUN@1224|Proteobacteria,2VKVR@28216|Betaproteobacteria,4AATD@80864|Comamonadaceae	28216|Betaproteobacteria	P	Mg2 transporter protein cora family protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ZZS3_k127_2068415_1	1100721.ALKO01000027_gene353	8.41e-186	585.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,4AB2M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
ZZS3_k127_2068415_6	358220.C380_01800	7.086e-68	234.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,4ADZI@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
ZZS3_k127_2068415_2	365046.Rta_03170	4.506e-167	532.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,4ABFG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
ZZS3_k127_2068415_7	365046.Rta_03180	1.328e-51	201.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,4AEGC@80864|Comamonadaceae	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
ZZS3_k127_2068415_5	595537.Varpa_5601	1.689e-91	309.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,4A9RP@80864|Comamonadaceae	28216|Betaproteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Thioesterase
ZZS3_k127_2068415_0	365046.Rta_03200	1.106e-197	624.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,4AAD0@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
ZZS3_k127_2068415_9	987059.RBXJA2T_16242	9.893e-16	78.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,1KJXU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	Aminotransferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
ZZS3_k127_2087226_2	365046.Rta_16150	0.0	1032.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,4AACA@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ZZS3_k127_2087226_6	365046.Rta_16140	2.65e-204	647.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1PETU@1224|Proteobacteria,2VPRD@28216|Betaproteobacteria	28216|Betaproteobacteria	CE	FAD dependent oxidoreductase	-	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO,Rieske
ZZS3_k127_2087226_14	365046.Rta_16130	3.428e-31	124.0	2E54W@1|root,32ZXT@2|Bacteria,1N7HQ@1224|Proteobacteria,2VWQP@28216|Betaproteobacteria,4AFC9@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2087226_13	358220.C380_15650	1.222e-46	169.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,4AEW8@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_2087226_10	420662.Mpe_A1788	4.117e-111	364.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,1KKPM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
ZZS3_k127_2087226_0	365046.Rta_15940	0.0	1239.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,4AARI@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS3_k127_2087226_12	365046.Rta_15930	1.868e-94	314.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,4A9XY@80864|Comamonadaceae	28216|Betaproteobacteria	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
ZZS3_k127_2087226_11	365046.Rta_15920	1.261e-109	358.0	COG1802@1|root,COG1802@2|Bacteria,1RE3J@1224|Proteobacteria,2VQMY@28216|Betaproteobacteria,4AD4W@80864|Comamonadaceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_2087226_5	365046.Rta_15910	1.468e-210	657.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VK50@28216|Betaproteobacteria,4AAVC@80864|Comamonadaceae	28216|Betaproteobacteria	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS3_k127_2087226_9	365046.Rta_15900	1.967e-174	552.0	COG1995@1|root,COG1995@2|Bacteria,1MXGJ@1224|Proteobacteria,2VISV@28216|Betaproteobacteria,4ABVP@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
ZZS3_k127_2087226_4	365046.Rta_15890	3.444e-269	837.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VM50@28216|Betaproteobacteria,4ADW9@80864|Comamonadaceae	28216|Betaproteobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
ZZS3_k127_2087226_7	365046.Rta_15880	2.64e-199	624.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VMWH@28216|Betaproteobacteria,4AJ34@80864|Comamonadaceae	28216|Betaproteobacteria	P	TOBE domain	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
ZZS3_k127_2087226_3	365046.Rta_15870	4.028e-303	937.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,4AJ5Z@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
ZZS3_k127_2087226_8	365046.Rta_15860	1.064e-192	605.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria	1224|Proteobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
ZZS3_k127_2087226_1	614083.AWQR01000030_gene2817	0.0	1239.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,4ABU3@80864|Comamonadaceae	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
ZZS3_k127_2101893_1	365046.Rta_23660	7.937e-164	517.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,4AA00@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM isocitrate lyase and phosphorylmutase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
ZZS3_k127_2101893_3	1173026.Glo7428_2420	1.025e-100	360.0	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS3_k127_2101893_0	1276756.AUEX01000011_gene1326	0.0	1167.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,4AB8C@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
ZZS3_k127_2101893_2	232721.Ajs_2399	1.825e-105	343.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,4AAWJ@80864|Comamonadaceae	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
ZZS3_k127_2107755_1	94624.Bpet2407	5.099e-160	505.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VHV4@28216|Betaproteobacteria,3T6G4@506|Alcaligenaceae	28216|Betaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_2107755_11	1333856.L686_13885	1.411e-49	178.0	COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,1SA90@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2107755_15	196367.JNFG01000033_gene7429	1.673e-19	95.0	COG1395@1|root,COG1395@2|Bacteria,1RFQP@1224|Proteobacteria,2WGHD@28216|Betaproteobacteria,1K9TR@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ZZS3_k127_2107755_4	614083.AWQR01000005_gene1210	5.431e-129	416.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VJPZ@28216|Betaproteobacteria,4A9Y3@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
ZZS3_k127_2107755_10	1218084.BBJK01000012_gene1328	1.223e-53	198.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1JZUB@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
ZZS3_k127_2107755_3	670292.JH26_15760	1.09e-135	449.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2TTQ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP-type C4-dicarboxylate transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_2107755_13	1040986.ATYO01000006_gene353	6.556e-40	167.0	COG3090@1|root,COG3090@2|Bacteria,1RE57@1224|Proteobacteria,2U7GP@28211|Alphaproteobacteria,43K5J@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_2107755_0	864069.MicloDRAFT_00066840	4.993e-170	548.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,1JTRM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	TIGRFAM TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_2107755_5	1366050.N234_18070	6.071e-116	379.0	COG0656@1|root,COG0656@2|Bacteria,1MUH2@1224|Proteobacteria,2VJNQ@28216|Betaproteobacteria,1K0GK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	aldo keto reductase	-	-	1.1.1.21	ko:K00011	ko00040,ko00051,ko00052,ko00561,ko00790,ko01100,map00040,map00051,map00052,map00561,map00790,map01100	-	R01036,R01041,R01093,R01095,R01431,R01758,R01759,R01787,R02531,R02577,R04285,R11764	RC00099,RC00108,RC00133,RC00205,RC00670	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
ZZS3_k127_2107755_8	1158292.JPOE01000005_gene868	1.427e-75	254.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHJD@28216|Betaproteobacteria,1KPGW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yghU	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
ZZS3_k127_2107755_7	1123060.JONP01000002_gene1002	2.231e-81	273.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria,2JQ9R@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
ZZS3_k127_2107755_14	232721.Ajs_3200	1.257e-27	114.0	2E71B@1|root,331K0@2|Bacteria,1NBWQ@1224|Proteobacteria,2VWU3@28216|Betaproteobacteria,4AFFD@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2107755_9	365046.Rta_00110	2.341e-75	258.0	COG0847@1|root,COG0847@2|Bacteria,1R8JT@1224|Proteobacteria,2WGGB@28216|Betaproteobacteria,4ABY1@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
ZZS3_k127_2107755_6	1458275.AZ34_15505	6.83e-106	349.0	COG1187@1|root,COG1187@2|Bacteria,1REW2@1224|Proteobacteria,2WFF5@28216|Betaproteobacteria,4AJSG@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS3_k127_2107755_2	864051.BurJ1DRAFT_0694	7.487e-157	499.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2VKIK@28216|Betaproteobacteria,1KM3D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	garR	-	1.1.1.31,1.1.1.411	ko:K00020,ko:K08319	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_2107755_12	543728.Vapar_6013	5.31e-41	155.0	COG0782@1|root,COG0782@2|Bacteria,1MZNY@1224|Proteobacteria,2VUAK@28216|Betaproteobacteria,4AF83@80864|Comamonadaceae	28216|Betaproteobacteria	J	Elongation factor	rnk	-	-	ko:K06140	-	-	-	-	ko00000,ko03000	-	-	-	GreA_GreB,Rnk_N
ZZS3_k127_2126350_8	596154.Alide2_3616	1.282e-59	207.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2VH6T@28216|Betaproteobacteria,4ABNG@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
ZZS3_k127_2126350_4	365046.Rta_17320	6.12e-94	330.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2VHKF@28216|Betaproteobacteria,4AAV5@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM metallophosphoesterase	cpdA	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_2126350_6	365046.Rta_17310	4.487e-81	282.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VM11@28216|Betaproteobacteria,4ADN7@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
ZZS3_k127_2126350_3	365046.Rta_17300	3.618e-96	324.0	COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,2VQW2@28216|Betaproteobacteria,4ABVG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
ZZS3_k127_2126350_2	365046.Rta_17290	1.2e-152	484.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,4A9UZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	ompR	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_2126350_1	365046.Rta_17280	8.015e-258	801.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria,4A9M8@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	risS	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,RisS_PPD
ZZS3_k127_2126350_7	887062.HGR_09710	4.683e-67	243.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,4ADJH@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
ZZS3_k127_2126350_5	338969.Rfer_1332	3.584e-91	305.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,4ACVC@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
ZZS3_k127_2126350_0	365046.Rta_17250	0.0	1855.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,4AAFE@80864|Comamonadaceae	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
ZZS3_k127_2163248_14	365046.Rta_22620	0.0005371	47.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,4ACI0@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
ZZS3_k127_2163248_10	365046.Rta_22610	2.392e-51	206.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2VSQB@28216|Betaproteobacteria,4AECP@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Uncharacterised conserved protein UCP030820	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
ZZS3_k127_2163248_1	365046.Rta_22600	0.0	1123.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,4AA3Z@80864|Comamonadaceae	28216|Betaproteobacteria	C	nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
ZZS3_k127_2163248_13	296591.Bpro_2342	2.012e-42	166.0	COG0745@1|root,COG0745@2|Bacteria,1PW05@1224|Proteobacteria,2WBMC@28216|Betaproteobacteria,4AHYY@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_2163248_4	365046.Rta_22590	3.341e-182	588.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,4AA02@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
ZZS3_k127_2163248_11	596154.Alide2_3093	9.128e-50	177.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,4AEC5@80864|Comamonadaceae	28216|Betaproteobacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
ZZS3_k127_2163248_3	358220.C380_10210	9.634e-186	585.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,4AAD7@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
ZZS3_k127_2163248_8	1268622.AVS7_01269	4.554e-80	272.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VKQS@28216|Betaproteobacteria,4AC8E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM NADPH-dependent FMN reductase	azr	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
ZZS3_k127_2163248_7	614083.AWQR01000020_gene166	1.374e-89	300.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2VK5E@28216|Betaproteobacteria,4AAXC@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
ZZS3_k127_2163248_6	296591.Bpro_2373	1.726e-128	417.0	COG0583@1|root,COG0583@2|Bacteria,1MXDQ@1224|Proteobacteria,2VHNE@28216|Betaproteobacteria,4A9U5@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2163248_12	62928.azo2659	3.186e-45	181.0	2BVFD@1|root,32QUS@2|Bacteria,1RHF0@1224|Proteobacteria,2VT3V@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
ZZS3_k127_2163248_5	76114.ebA6917	6.074e-145	493.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,2KU77@206389|Rhodocyclales	206389|Rhodocyclales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
ZZS3_k127_2163248_0	397945.Aave_2985	0.0	1819.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria,4AD3R@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMART alpha amylase catalytic sub domain	treY	-	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
ZZS3_k127_2163248_2	397945.Aave_2984	1.707e-228	733.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2VJDX@28216|Betaproteobacteria,4AA76@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMART alpha amylase catalytic sub domain	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
ZZS3_k127_2163248_9	397945.Aave_2983	2.237e-61	218.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2VH8E@28216|Betaproteobacteria,4AC1I@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM glycoside hydrolase, family 13 domain protein	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
ZZS3_k127_2173887_10	1123504.JQKD01000002_gene3865	1.2e-35	138.0	COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,2VMD4@28216|Betaproteobacteria,4AAAC@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08169	-	-	-	-	ko00000,ko02000	2.A.1.3.17	-	-	MFS_1,Sugar_tr
ZZS3_k127_2173887_5	1123504.JQKD01000002_gene3544	6.651e-130	417.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,4ACDR@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the GST superfamily	gstI	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_2
ZZS3_k127_2173887_8	365046.Rta_22090	2.794e-68	239.0	2ECFI@1|root,336DT@2|Bacteria,1NBHQ@1224|Proteobacteria,2VW1X@28216|Betaproteobacteria,4AHYX@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2173887_1	365046.Rta_22080	9.894e-250	773.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VI1V@28216|Betaproteobacteria,4ABKZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_2173887_2	543728.Vapar_2629	2.182e-197	619.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2VJ31@28216|Betaproteobacteria,4A9R4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS3_k127_2173887_6	1223521.BBJX01000005_gene2065	8.978e-128	417.0	COG0664@1|root,COG0664@2|Bacteria,1RE4X@1224|Proteobacteria,2VMCY@28216|Betaproteobacteria,4ABJ0@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_2173887_7	365046.Rta_22050	7.81e-117	404.0	COG1024@1|root,COG1024@2|Bacteria,1P3FI@1224|Proteobacteria,2VHYZ@28216|Betaproteobacteria,4AAGR@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_2173887_0	365046.Rta_22040	9.112e-276	854.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria,4AAAP@80864|Comamonadaceae	28216|Betaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
ZZS3_k127_2173887_9	365046.Rta_22030	1.023e-36	157.0	COG3170@1|root,COG3170@2|Bacteria,1R5KB@1224|Proteobacteria,2VMU6@28216|Betaproteobacteria,4AA1R@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2173887_3	614083.AWQR01000018_gene1805	2.097e-153	505.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,4AD7H@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
ZZS3_k127_2173887_4	397945.Aave_3158	2.169e-136	436.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2VHIZ@28216|Betaproteobacteria,4A9J1@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_2176288_5	595537.Varpa_2143	7.731e-149	497.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VKK2@28216|Betaproteobacteria,4AA80@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
ZZS3_k127_2176288_2	595537.Varpa_2142	3.416e-200	643.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria,2VM3U@28216|Betaproteobacteria,4ABJX@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	3.11.1.2	ko:K19670	ko00440,map00440	-	R00318	RC01309	ko00000,ko00001,ko01000	-	-	-	Phosphodiest
ZZS3_k127_2176288_6	595537.Varpa_2141	6.094e-141	465.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2VI8W@28216|Betaproteobacteria,4ABGX@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphonate ABC transporter, inner membrane subunit	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ZZS3_k127_2176288_8	595537.Varpa_2140	7.466e-110	384.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2VIEZ@28216|Betaproteobacteria,4AD3N@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
ZZS3_k127_2176288_4	595537.Varpa_2139	1.966e-153	490.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,2VJKI@28216|Betaproteobacteria,4AD18@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
ZZS3_k127_2176288_7	1123504.JQKD01000017_gene1792	2.311e-135	437.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VKRV@28216|Betaproteobacteria,4ADM9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2176288_10	543728.Vapar_6332	1.066e-43	169.0	COG2823@1|root,COG2823@2|Bacteria,1PWII@1224|Proteobacteria,2WC32@28216|Betaproteobacteria,4AISP@80864|Comamonadaceae	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS3_k127_2176288_9	543728.Vapar_6330	7.492e-58	207.0	COG0517@1|root,COG0517@2|Bacteria,1QTWY@1224|Proteobacteria,2VTYW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS3_k127_2176288_11	1122201.AUAZ01000056_gene35	0.0009325	46.0	2AWWV@1|root,31NUD@2|Bacteria,1QPF3@1224|Proteobacteria,1SJ55@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2176288_3	365046.Rta_10380	2.667e-198	619.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,4ABWQ@80864|Comamonadaceae	28216|Betaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
ZZS3_k127_2176288_1	1123393.KB891333_gene2507	5.634e-236	734.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ZZS3_k127_2176288_0	365046.Rta_10390	0.0	1526.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,4ABDB@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
ZZS3_k127_2189878_6	926569.ANT_19610	4.897e-47	186.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_2189878_3	375286.mma_3306	2.402e-135	439.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,47350@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Pirin C-terminal cupin domain	yhhW_1	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
ZZS3_k127_2189878_1	375286.mma_3305	1.038e-141	454.0	COG0583@1|root,COG0583@2|Bacteria,1MXDQ@1224|Proteobacteria,2VHNE@28216|Betaproteobacteria,473TD@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2189878_5	1157708.KB907462_gene1023	1.518e-63	227.0	COG2188@1|root,COG2188@2|Bacteria,1MX3T@1224|Proteobacteria,2VQVR@28216|Betaproteobacteria,4ADVC@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
ZZS3_k127_2189878_0	1205680.CAKO01000026_gene4592	9.526e-154	492.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2189878_4	1500897.JQNA01000002_gene4708	4.226e-113	383.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VZBQ@28216|Betaproteobacteria,1K5FI@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.32	ko:K20454	ko00760,ko01120,map00760,map01120	-	R01355	RC00286,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
ZZS3_k127_2189878_2	224911.27348664	9.022e-138	461.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TVD2@28211|Alphaproteobacteria,3JURG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
ZZS3_k127_2236461_27	1121378.KB899710_gene1347	2.591e-23	98.0	COG0183@1|root,COG0183@2|Bacteria,1WIAR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_2236461_1	365046.Rta_20030	0.0	1087.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VH3R@28216|Betaproteobacteria,4ABBE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
ZZS3_k127_2236461_28	1157708.KB907450_gene5731	7.795e-08	61.0	2EVGE@1|root,33NWT@2|Bacteria,1NGBG@1224|Proteobacteria,2VZ1Y@28216|Betaproteobacteria,4AFTJ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2236461_11	365046.Rta_20010	1.987e-143	463.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2VH22@28216|Betaproteobacteria,4AAMM@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	gno1	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
ZZS3_k127_2236461_23	365046.Rta_20000	8.389e-57	202.0	COG2050@1|root,COG2050@2|Bacteria,1MYG1@1224|Proteobacteria,2VTQD@28216|Betaproteobacteria,4ADXA@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_2236461_5	365046.Rta_19990	4.278e-194	608.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2VIE7@28216|Betaproteobacteria,4AAQT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
ZZS3_k127_2236461_8	365046.Rta_19980	1.949e-163	520.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2VSCY@28216|Betaproteobacteria,4AEWX@80864|Comamonadaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
ZZS3_k127_2236461_2	1265502.KB905940_gene2991	6.446e-234	737.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VHMA@28216|Betaproteobacteria,4A9UE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
ZZS3_k127_2236461_7	365046.Rta_19960	2.549e-173	548.0	COG0625@1|root,COG0625@2|Bacteria,1P71B@1224|Proteobacteria,2VJ3I@28216|Betaproteobacteria,4AB01@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
ZZS3_k127_2236461_22	296591.Bpro_2560	7.335e-57	221.0	COG0350@1|root,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,2VRTX@28216|Betaproteobacteria,4AE2A@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
ZZS3_k127_2236461_26	365046.Rta_19940	1.42e-35	145.0	2B4TG@1|root,31XK1@2|Bacteria,1RIY8@1224|Proteobacteria,2VTMB@28216|Betaproteobacteria,4AF7U@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2236461_0	365046.Rta_19930	0.0	1353.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,4AA13@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA binding S1 domain protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
ZZS3_k127_2236461_25	365046.Rta_19910	2.964e-39	160.0	COG0515@1|root,COG0515@2|Bacteria	365046.Rta_19910|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2236461_17	365046.Rta_19900	2.491e-108	362.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
ZZS3_k127_2236461_6	358220.C380_10645	3.002e-176	557.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,2VHBX@28216|Betaproteobacteria,4AC7Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
ZZS3_k127_2236461_3	296591.Bpro_2526	4.887e-218	679.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4A9Y2@80864|Comamonadaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	gbd1	-	1.1.1.1,1.1.1.61	ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
ZZS3_k127_2236461_13	365046.Rta_19880	1.032e-141	456.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VJSB@28216|Betaproteobacteria,4ACH0@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
ZZS3_k127_2236461_15	1123504.JQKD01000002_gene3902	7.199e-125	407.0	COG0824@1|root,COG2153@1|root,COG0824@2|Bacteria,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,4A9NN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thioesterase superfamily protein	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
ZZS3_k127_2236461_4	296591.Bpro_2523	3.144e-217	696.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1PVBG@1224|Proteobacteria,2WB76@28216|Betaproteobacteria,4AH21@80864|Comamonadaceae	28216|Betaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS3_k127_2236461_14	1276756.AUEX01000003_gene847	1.548e-125	408.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,4AAKV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
ZZS3_k127_2236461_9	1157708.KB907450_gene5814	3.552e-145	469.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,4ABZJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
ZZS3_k127_2236461_19	614083.AWQR01000004_gene901	6.506e-88	306.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,4AAAH@80864|Comamonadaceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
ZZS3_k127_2236461_10	365046.Rta_19830	3.971e-144	476.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,4AB1J@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
ZZS3_k127_2236461_21	296591.Bpro_2517	2.761e-59	207.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria,4AEEB@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type IV pilus assembly PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
ZZS3_k127_2236461_12	365046.Rta_19810	6.937e-143	457.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,4AAED@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ZZS3_k127_2236461_20	365046.Rta_19800	4.98e-87	302.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,4ADCG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Ankyrin	arp3	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
ZZS3_k127_2236461_16	1192124.LIG30_2838	6.545e-118	383.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1K6MB@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
ZZS3_k127_2236461_18	365044.Pnap_1045	1.671e-98	325.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,4A9RT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
ZZS3_k127_2236461_24	1276756.AUEX01000001_gene1090	1.736e-39	156.0	COG0720@1|root,COG0720@2|Bacteria,1PSH6@1224|Proteobacteria,2VUV7@28216|Betaproteobacteria,4AEIY@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
ZZS3_k127_2303964_4	296591.Bpro_2029	4.498e-70	238.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,4AAXB@80864|Comamonadaceae	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
ZZS3_k127_2303964_0	365046.Rta_15760	0.0	1727.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,4AC02@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS3_k127_2303964_2	595537.Varpa_3425	8.795e-145	469.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,4AAUX@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_2303964_3	365046.Rta_15740	3.434e-108	357.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,4AA62@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
ZZS3_k127_2303964_1	595537.Varpa_3428	3.565e-149	484.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,4AA6R@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
ZZS3_k127_2310182_0	1458275.AZ34_16430	7.073e-166	526.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2VI6J@28216|Betaproteobacteria,4A9XB@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
ZZS3_k127_2310182_7	365046.Rta_37630	2.015e-60	214.0	COG5592@1|root,COG5592@2|Bacteria,1RCHC@1224|Proteobacteria,2VQQY@28216|Betaproteobacteria,4ADTC@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_2310182_4	595537.Varpa_1190	2.277e-110	365.0	COG0583@1|root,COG0583@2|Bacteria,1Q6E2@1224|Proteobacteria,2WEW0@28216|Betaproteobacteria,4AIZP@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2310182_1	543728.Vapar_1106	3.094e-142	473.0	COG3181@1|root,COG3181@2|Bacteria,1QW9H@1224|Proteobacteria,2VJ0I@28216|Betaproteobacteria,4ACFG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2310182_2	1157708.KB907452_gene3910	8.954e-131	451.0	COG1995@1|root,COG1995@2|Bacteria,1MXGJ@1224|Proteobacteria,2VISV@28216|Betaproteobacteria,4ABVP@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
ZZS3_k127_2310182_10	626887.J057_11346	9.822e-33	135.0	COG1247@1|root,COG1247@2|Bacteria,1R11U@1224|Proteobacteria,1T4VT@1236|Gammaproteobacteria,4697M@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_2310182_12	1268237.G114_06457	4.838e-07	58.0	COG0454@1|root,COG0456@2|Bacteria,1MZUT@1224|Proteobacteria,1S4BD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_2310182_8	296591.Bpro_2365	1.021e-48	178.0	2APJ5@1|root,31EN8@2|Bacteria,1RIPC@1224|Proteobacteria,2VT2M@28216|Betaproteobacteria,4AF9Q@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2310182_6	290397.Adeh_3195	3.454e-69	239.0	COG5649@1|root,COG5649@2|Bacteria,1RDDG@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS3_k127_2310182_11	745411.B3C1_00055	7.24e-23	102.0	COG0457@1|root,COG0457@2|Bacteria	745411.B3C1_00055|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2310182_3	1472716.KBK24_0125520	5.635e-112	364.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,1K4BD@119060|Burkholderiaceae	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS3_k127_2310182_5	296591.Bpro_1648	2.3e-93	307.0	COG0346@1|root,COG0346@2|Bacteria,1RABI@1224|Proteobacteria,2VVN9@28216|Betaproteobacteria,4AI4B@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
ZZS3_k127_231644_3	365046.Rta_20950	5.405e-183	576.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,4A9TX@80864|Comamonadaceae	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
ZZS3_k127_231644_4	365046.Rta_20940	6.307e-157	503.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,4ABGH@80864|Comamonadaceae	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
ZZS3_k127_231644_2	1123392.AQWL01000004_gene2671	9.386e-276	865.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1KRFU@119069|Hydrogenophilales	119069|Hydrogenophilales	L	breast cancer carboxy-terminal domain	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
ZZS3_k127_231644_9	365044.Pnap_1817	1.304e-32	133.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria,4AENJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	ybaN	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
ZZS3_k127_231644_8	365046.Rta_20400	2.975e-92	305.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,4A9KP@80864|Comamonadaceae	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ZZS3_k127_231644_7	762376.AXYL_03885	2.025e-121	399.0	COG3181@1|root,COG3181@2|Bacteria,1R8WK@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_231644_5	365046.Rta_33640	1.074e-151	485.0	COG3181@1|root,COG3181@2|Bacteria,1NEU9@1224|Proteobacteria,2VHYX@28216|Betaproteobacteria,4AC1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_231644_1	365046.Rta_20350	0.0	1389.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,4AA9J@80864|Comamonadaceae	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
ZZS3_k127_231644_6	365046.Rta_20340	1.747e-146	515.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,4AA2U@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM methionine aminopeptidase, type I	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
ZZS3_k127_231644_0	1123504.JQKD01000002_gene3822	0.0	1973.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,4AARH@80864|Comamonadaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
ZZS3_k127_2323403_7	365046.Rta_30500	3.795e-89	293.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,4ACIE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
ZZS3_k127_2323403_0	365046.Rta_30510	0.0	1888.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,4ACV8@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS3_k127_2323403_12	296591.Bpro_0936	4.199e-16	79.0	2ENGM@1|root,33G44@2|Bacteria,1NIB7@1224|Proteobacteria,2VYFS@28216|Betaproteobacteria,4AG1A@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2323403_8	365046.Rta_30550	1.462e-85	312.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,4ACXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	cytoplasmic chaperone TorD family protein	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
ZZS3_k127_2323403_2	365046.Rta_30560	0.0	1036.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,4ABEA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
ZZS3_k127_2323403_10	1031711.RSPO_c01070	1.036e-30	132.0	2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,1K8AT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
ZZS3_k127_2323403_9	365046.Rta_30580	1.773e-83	289.0	2DBXD@1|root,2ZBP6@2|Bacteria,1RB44@1224|Proteobacteria,2VQT3@28216|Betaproteobacteria,4ADT6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
ZZS3_k127_2323403_4	365046.Rta_30610	6.898e-194	616.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,4AA3H@80864|Comamonadaceae	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
ZZS3_k127_2323403_1	365046.Rta_30620	0.0	1068.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,4A9M6@80864|Comamonadaceae	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
ZZS3_k127_2323403_13	1123504.JQKD01000036_gene3133	6.82e-05	47.0	2ECJW@1|root,336I0@2|Bacteria,1N8YK@1224|Proteobacteria,2VWUU@28216|Betaproteobacteria,4AFR6@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2323403_3	543728.Vapar_4088	4.428e-229	723.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2VH45@28216|Betaproteobacteria,4AA5E@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ZZS3_k127_2323403_11	365046.Rta_30650	2.366e-26	109.0	2E9SN@1|root,32ZFH@2|Bacteria,1N8MD@1224|Proteobacteria,2VW4H@28216|Betaproteobacteria,4AFFC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3460
ZZS3_k127_2323403_5	365046.Rta_30660	1.227e-146	471.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,4AB2X@80864|Comamonadaceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
ZZS3_k127_2323403_6	365046.Rta_30670	2.552e-113	369.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,4AA3F@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS3_k127_2342569_1	543728.Vapar_5519	2.377e-189	611.0	COG4948@1|root,COG4948@2|Bacteria,1MW3F@1224|Proteobacteria,2VP7A@28216|Betaproteobacteria,4AF3H@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_2342569_5	543728.Vapar_5518	1.752e-119	393.0	COG2188@1|root,COG2188@2|Bacteria,1MVPT@1224|Proteobacteria,2VP7X@28216|Betaproteobacteria,4AJKC@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
ZZS3_k127_2342569_4	543728.Vapar_5517	1.371e-131	424.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VPER@28216|Betaproteobacteria,4AIYF@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ZZS3_k127_2342569_3	543728.Vapar_5516	1.236e-146	482.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,4ACPW@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
ZZS3_k127_2342569_2	543728.Vapar_5515	2.644e-177	560.0	COG0715@1|root,COG0715@2|Bacteria,1MVUJ@1224|Proteobacteria,2VNPD@28216|Betaproteobacteria,4AH2F@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051,ko:K15551	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	NMT1
ZZS3_k127_2342569_0	1123504.JQKD01000059_gene2939	9.228e-266	844.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
ZZS3_k127_2342569_8	502025.Hoch_4766	1.471e-30	132.0	2DBEV@1|root,2Z8UT@2|Bacteria,1N26S@1224|Proteobacteria,42WPK@68525|delta/epsilon subdivisions,2WS9G@28221|Deltaproteobacteria,2YV3S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2342569_6	365046.Rta_06120	2.266e-47	175.0	COG0782@1|root,COG0782@2|Bacteria,1MZNY@1224|Proteobacteria,2VUAK@28216|Betaproteobacteria,4AF83@80864|Comamonadaceae	28216|Betaproteobacteria	J	Elongation factor	rnk	-	-	ko:K06140	-	-	-	-	ko00000,ko03000	-	-	-	GreA_GreB,Rnk_N
ZZS3_k127_2342569_7	365046.Rta_06110	9.757e-44	175.0	COG0589@1|root,COG0589@2|Bacteria,1P23N@1224|Proteobacteria,2W463@28216|Betaproteobacteria,4AID6@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_234562_5	614083.AWQR01000005_gene1177	5.843e-82	277.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2VPWT@28216|Betaproteobacteria,4ADDQ@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_234562_6	365046.Rta_11410	7.029e-67	234.0	COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,2VT0A@28216|Betaproteobacteria,4AEH5@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_234562_1	614083.AWQR01000005_gene1175	1.576e-187	594.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,4ABJD@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_234562_8	1366050.N234_32640	8.629e-17	85.0	COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,2VW4A@28216|Betaproteobacteria,1KA7F@119060|Burkholderiaceae	28216|Betaproteobacteria	K	copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
ZZS3_k127_234562_9	159450.NH14_09140	1.855e-13	72.0	COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,2VW4A@28216|Betaproteobacteria,1KA7F@119060|Burkholderiaceae	28216|Betaproteobacteria	K	copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
ZZS3_k127_234562_3	365044.Pnap_1241	8.676e-131	422.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2VM30@28216|Betaproteobacteria,4AA37@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_234562_7	296591.Bpro_3535	2.288e-66	245.0	COG0800@1|root,COG0800@2|Bacteria,1RD0T@1224|Proteobacteria,2VKJG@28216|Betaproteobacteria,4ADTS@80864|Comamonadaceae	28216|Betaproteobacteria	G	KDPG and KHG aldolase	dgoA	-	4.1.2.21	ko:K01631	ko00052,ko01100,map00052,map01100	M00552	R01064	RC00307,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
ZZS3_k127_234562_4	595537.Varpa_4264	1.052e-105	353.0	COG3734@1|root,COG3734@2|Bacteria,1MWGX@1224|Proteobacteria,2VH7M@28216|Betaproteobacteria,4ABYZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	2-keto-3-deoxy-galactonokinase	dgoK	-	2.7.1.58	ko:K00883	ko00052,ko01100,map00052,map01100	M00552	R03387	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DGOK
ZZS3_k127_234562_0	365046.Rta_11490	0.0	1090.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.25,4.2.1.9	ko:K01687,ko:K13875	ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02522,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ZZS3_k127_234562_2	1144342.PMI40_00589	1.86e-158	503.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2VNEK@28216|Betaproteobacteria,477GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ZZS3_k127_2361093_2	296591.Bpro_4074	1.231e-129	434.0	COG3712@1|root,COG3712@2|Bacteria,1N941@1224|Proteobacteria,2VIKR@28216|Betaproteobacteria,4AGN3@80864|Comamonadaceae	28216|Betaproteobacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR
ZZS3_k127_2361093_5	296591.Bpro_0549	3.045e-108	369.0	COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,2VQ74@28216|Betaproteobacteria,4ADI7@80864|Comamonadaceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_2361093_4	296591.Bpro_0550	1.012e-115	377.0	COG3473@1|root,COG3473@2|Bacteria,1MU9Z@1224|Proteobacteria,2VN2P@28216|Betaproteobacteria,4ADSS@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Asp Glu hydantoin racemase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
ZZS3_k127_2361093_0	296591.Bpro_0551	7.54e-261	810.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2VJZV@28216|Betaproteobacteria,4ABSY@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1,Urease_alpha
ZZS3_k127_2361093_3	296591.Bpro_0552	1.518e-122	396.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2VKM5@28216|Betaproteobacteria,4AJCS@80864|Comamonadaceae	28216|Betaproteobacteria	E	Asp/Glu/Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
ZZS3_k127_2361093_1	296591.Bpro_0553	6.967e-170	537.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,4A9T2@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_2361093_7	296591.Bpro_0554	7.645e-66	229.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2VWZB@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
ZZS3_k127_2361093_6	296591.Bpro_0555	2.012e-97	325.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4ACPD@80864|Comamonadaceae	28216|Betaproteobacteria	G	Trap dicarboxylate transporter, dctm subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_2362428_25	1123504.JQKD01000013_gene1021	1.59e-58	222.0	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2VQI0@28216|Betaproteobacteria,4AE5G@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
ZZS3_k127_2362428_16	1123504.JQKD01000013_gene1022	1.15e-120	400.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,2VJ03@28216|Betaproteobacteria,4AAF2@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM phenylacetic acid catabolic family protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
ZZS3_k127_2362428_26	1157708.KB907452_gene3756	4.797e-51	196.0	COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,2VSR2@28216|Betaproteobacteria,4AEMJ@80864|Comamonadaceae	28216|Betaproteobacteria	Q	TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
ZZS3_k127_2362428_3	1123504.JQKD01000013_gene1024	1.493e-203	635.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2VHQZ@28216|Betaproteobacteria,4A9YX@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM phenylacetic acid catabolic family protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
ZZS3_k127_2362428_20	762376.AXYL_06225	1.313e-75	261.0	COG1414@1|root,COG1414@2|Bacteria,1PXJ1@1224|Proteobacteria,2WCYI@28216|Betaproteobacteria,3T6HC@506|Alcaligenaceae	28216|Betaproteobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_2362428_22	1424334.W822_18520	3.412e-70	252.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2W21K@28216|Betaproteobacteria,3T3V2@506|Alcaligenaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
ZZS3_k127_2362428_8	762376.AXYL_06228	3.752e-175	563.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VIFU@28216|Betaproteobacteria,3T8PM@506|Alcaligenaceae	28216|Betaproteobacteria	H	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_2362428_18	1532557.JL37_13430	1.134e-110	366.0	COG3181@1|root,COG3181@2|Bacteria,1PU5U@1224|Proteobacteria,2WAQB@28216|Betaproteobacteria,3T6EK@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2362428_24	1286631.X805_25030	3.83e-62	218.0	COG1522@1|root,COG1522@2|Bacteria,1RJ7F@1224|Proteobacteria,2VTCR@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
ZZS3_k127_2362428_0	595537.Varpa_1088	0.0	1745.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,4AC8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
ZZS3_k127_2362428_1	365046.Rta_33450	0.0	1073.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD4	-	4.2.1.25,4.2.1.9	ko:K01687,ko:K13875	ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02522,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ZZS3_k127_2362428_4	365046.Rta_33440	2.784e-193	604.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJ08@28216|Betaproteobacteria,4AD8R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2362428_15	1216976.AX27061_1266	6.334e-125	425.0	COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2VIKK@28216|Betaproteobacteria,3T6I6@506|Alcaligenaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS3_k127_2362428_27	946483.Cenrod_0699	4.299e-43	176.0	COG4564@1|root,COG4564@2|Bacteria,1RJP6@1224|Proteobacteria,2WEEN@28216|Betaproteobacteria,4AHTM@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
ZZS3_k127_2362428_21	1157708.KB907465_gene336	1.3e-71	246.0	2DBG4@1|root,2Z927@2|Bacteria,1N7I6@1224|Proteobacteria,2VQ2P@28216|Betaproteobacteria,4AD4X@80864|Comamonadaceae	28216|Betaproteobacteria	K	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways	flhC	-	-	ko:K02402	ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlhC
ZZS3_k127_2362428_28	1157708.KB907465_gene337	2.03e-24	108.0	2AX91@1|root,31P80@2|Bacteria,1N25K@1224|Proteobacteria,2VSYQ@28216|Betaproteobacteria,4AEIJ@80864|Comamonadaceae	28216|Betaproteobacteria	N	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways	flhD	-	-	ko:K02403	ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlhD
ZZS3_k127_2362428_2	365046.Rta_33430	1.894e-318	977.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,4AB17@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	-	-	4.2.1.42,4.2.1.7,4.4.1.24	ko:K01685,ko:K01708,ko:K16846	ko00040,ko00053,ko00270,ko01100,map00040,map00053,map00270,map01100	M00631	R01540,R05608,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ZZS3_k127_2362428_19	762376.AXYL_01530	1.37e-103	349.0	COG3181@1|root,COG3181@2|Bacteria,1NTB7@1224|Proteobacteria,2W167@28216|Betaproteobacteria,3T6K7@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2362428_9	365046.Rta_33420	1.294e-162	517.0	COG0583@1|root,COG0583@2|Bacteria,1N178@1224|Proteobacteria,2VNFW@28216|Betaproteobacteria,4AA5C@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2362428_6	1223521.BBJX01000015_gene237	7.888e-182	577.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2VVJQ@28216|Betaproteobacteria,4AJBC@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_2362428_10	935261.JAGL01000006_gene2280	7.604e-153	492.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,43IF9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	1.14.13.1,1.14.13.24	ko:K00480,ko:K22270	ko00362,ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00362,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R02589,R05632,R06915,R06936,R06939	RC00046,RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_2362428_13	543728.Vapar_2058	8.545e-135	433.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2VKCA@28216|Betaproteobacteria,4AAV0@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ZZS3_k127_2362428_12	543728.Vapar_2057	8.351e-138	442.0	COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,2VMR7@28216|Betaproteobacteria,4AAAB@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ZZS3_k127_2362428_17	296591.Bpro_2237	1.033e-114	381.0	COG3638@1|root,COG3638@2|Bacteria,1MXYA@1224|Proteobacteria,2VM4F@28216|Betaproteobacteria,4A9J3@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
ZZS3_k127_2362428_11	543728.Vapar_2055	4.697e-145	463.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,4AAF8@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
ZZS3_k127_2362428_7	543728.Vapar_2054	4.426e-178	568.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4ABSP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
ZZS3_k127_2362428_14	543728.Vapar_2053	2.041e-134	438.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,4ACVF@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS3_k127_2362428_5	543728.Vapar_2052	2.18e-184	596.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,4AAPT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
ZZS3_k127_2362428_23	1123504.JQKD01000017_gene1804	7.159e-70	240.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2VKVI@28216|Betaproteobacteria,4AD8F@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_2406358_1	365046.Rta_04180	3.254e-220	690.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHEI@28216|Betaproteobacteria,4AC9Q@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_2406358_0	543728.Vapar_4810	0.0	1427.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,4AAYQ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.3.8.7,1.5.5.2	ko:K00249,ko:K00294,ko:K13821	ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051	RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
ZZS3_k127_2408845_4	365046.Rta_34310	1.371e-101	335.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,4AASK@80864|Comamonadaceae	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
ZZS3_k127_2408845_0	365046.Rta_34320	5.705e-297	931.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,4A9TE@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM peptidase M61 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
ZZS3_k127_2408845_5	365046.Rta_34330	1.466e-91	335.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria,4AATH@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
ZZS3_k127_2408845_1	365046.Rta_34340	5.357e-246	771.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,4AAJK@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
ZZS3_k127_2408845_6	365046.Rta_34350	1.372e-66	229.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2VRC2@28216|Betaproteobacteria,4AEJU@80864|Comamonadaceae	28216|Betaproteobacteria	Q	phenylacetic acid degradation protein PaaD	paaI	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
ZZS3_k127_2408845_3	365046.Rta_34360	4.55e-129	417.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2VHE9@28216|Betaproteobacteria,4ACR5@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS3_k127_2408845_2	365046.Rta_34370	1.948e-141	454.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,4A9TB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS3_k127_245335_3	365046.Rta_20410	2.615e-151	481.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,4AA2Y@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
ZZS3_k127_245335_4	365046.Rta_19360	9.307e-119	384.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,2VVI5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	plastoquinol--plastocyanin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_245335_0	365046.Rta_19370	1.827e-202	652.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VJD8@28216|Betaproteobacteria,4ABBG@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase, class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_245335_1	543728.Vapar_2726	2.218e-181	570.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,4A9K9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	cysB	-	-	ko:K13634,ko:K13635	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_245335_6	614083.AWQR01000048_gene3222	1.723e-38	147.0	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,2VTXE@28216|Betaproteobacteria,4AEWE@80864|Comamonadaceae	28216|Betaproteobacteria	S	cobalamin (vitamin B12) biosynthesis CbiX	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
ZZS3_k127_245335_2	365046.Rta_19400	2.814e-168	542.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,4ABSU@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS3_k127_245335_5	365046.Rta_19410	2.132e-52	188.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,4ABC9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS3_k127_2474379_3	596154.Alide2_3503	1.121e-170	549.0	COG0031@1|root,COG0031@2|Bacteria,1MUR6@1224|Proteobacteria,2VJEW@28216|Betaproteobacteria,4AAVG@80864|Comamonadaceae	28216|Betaproteobacteria	E	beta' subunit	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_2474379_14	637389.Acaty_c1951	1.121e-34	138.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,2NCYR@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS3_k127_2474379_9	596153.Alide_1412	4.486e-133	429.0	COG0583@1|root,COG0583@2|Bacteria,1N3XX@1224|Proteobacteria,2VJNW@28216|Betaproteobacteria,4AGHM@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2474379_8	596154.Alide2_3505	2.654e-137	460.0	COG0407@1|root,COG0407@2|Bacteria,1NDUE@1224|Proteobacteria,2VZ7U@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
ZZS3_k127_2474379_7	596153.Alide_1410	8.468e-140	455.0	COG3181@1|root,COG3181@2|Bacteria,1QCX7@1224|Proteobacteria,2VMUQ@28216|Betaproteobacteria,4AGBK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2474379_6	864051.BurJ1DRAFT_0183	1.137e-148	477.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,1KKHM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2474379_1	864051.BurJ1DRAFT_0182	6.997e-302	929.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KJRD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
ZZS3_k127_2474379_13	864051.BurJ1DRAFT_0181	7.203e-78	262.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,2VQKV@28216|Betaproteobacteria,1KKJ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ribulose bisphosphate carboxylase, small chain	cbbS	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
ZZS3_k127_2474379_5	983917.RGE_36030	1.323e-154	493.0	COG0464@1|root,COG0464@2|Bacteria,1MUCN@1224|Proteobacteria,2VIA8@28216|Betaproteobacteria,1KJSZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	cbbX	-	-	-	-	-	-	-	-	-	-	-	AAA
ZZS3_k127_2474379_11	365044.Pnap_1980	2.326e-100	353.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,4ACPT@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS3_k127_2474379_2	365044.Pnap_1982	7.63e-195	614.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,4ACN6@80864|Comamonadaceae	28216|Betaproteobacteria	G	carbohydrate phosphatase activity	fbp1	-	3.1.3.11,3.1.3.37	ko:K01086	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase
ZZS3_k127_2474379_4	395495.Lcho_3754	2.918e-166	531.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KIVW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoribulokinase	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
ZZS3_k127_2474379_0	1458427.BAWN01000011_gene669	0.0	1082.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,4AB6C@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the transketolase family	cbbT	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
ZZS3_k127_2474379_12	365044.Pnap_1985	6.48e-90	323.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,4AB3X@80864|Comamonadaceae	28216|Betaproteobacteria	G	HAD-superfamily hydrolase, subfamily IA, variant 1	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_2474379_10	1234364.AMSF01000010_gene600	3.079e-111	361.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1X34S@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS3_k127_2475558_1	365046.Rta_14690	3.129e-236	734.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4A9UW@80864|Comamonadaceae	28216|Betaproteobacteria	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_2475558_4	296591.Bpro_1870	5.041e-78	281.0	COG3090@1|root,COG3090@2|Bacteria,1N4RB@1224|Proteobacteria,2VT0R@28216|Betaproteobacteria,4ADIZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_2475558_2	365046.Rta_14710	2.823e-180	568.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VM68@28216|Betaproteobacteria,4AA1S@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	yiaO	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_2475558_0	1268622.AVS7_04689	5.143e-314	970.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,4AA63@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	DAO,ETF_QO,FAD_binding_2,NAD_binding_8
ZZS3_k127_2475558_3	365046.Rta_14730	8.543e-121	390.0	COG1028@1|root,COG1028@2|Bacteria,1MXWI@1224|Proteobacteria,2VJIU@28216|Betaproteobacteria,4AC2K@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	gno2	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_2518967_7	267608.RSc1152	1.764e-31	125.0	COG0583@1|root,COG0583@2|Bacteria,1MU7H@1224|Proteobacteria,2VISY@28216|Betaproteobacteria,1K0MI@119060|Burkholderiaceae	28216|Betaproteobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2518967_1	1268622.AVS7_04511	6.704e-184	585.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VKKF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS3_k127_2518967_5	395495.Lcho_2478	3.708e-69	243.0	COG4951@1|root,COG4951@2|Bacteria,1RE15@1224|Proteobacteria,2VSA8@28216|Betaproteobacteria,1KKWJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA primase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2518967_6	365046.Rta_27660	6.287e-63	239.0	COG1376@1|root,COG1376@2|Bacteria,1R7VK@1224|Proteobacteria,2VRX0@28216|Betaproteobacteria,4AE5A@80864|Comamonadaceae	28216|Betaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2518967_3	1123504.JQKD01000064_gene2462	1.699e-145	469.0	COG3181@1|root,COG3181@2|Bacteria,1MX9X@1224|Proteobacteria,2VKWC@28216|Betaproteobacteria,4AACQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2518967_0	1157708.KB907456_gene2205	6.013e-185	594.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2VN2T@28216|Betaproteobacteria,4ADCS@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
ZZS3_k127_2518967_2	365046.Rta_22560	1.694e-171	548.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2VKI0@28216|Betaproteobacteria,4AA08@80864|Comamonadaceae	28216|Betaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS3_k127_2518967_4	543728.Vapar_3209	1.144e-120	393.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2533419_0	365046.Rta_11630	1.149e-263	816.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAHM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA4	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
ZZS3_k127_2533419_6	296591.Bpro_3875	4.399e-34	141.0	COG5455@1|root,COG5455@2|Bacteria,1RJ9A@1224|Proteobacteria,2VRVC@28216|Betaproteobacteria,4AF8K@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
ZZS3_k127_2533419_1	365046.Rta_27580	3.883e-258	803.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,2VKVU@28216|Betaproteobacteria,4AA8S@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
ZZS3_k127_2533419_7	296591.Bpro_3362	5.116e-07	63.0	2FEQ9@1|root,346PG@2|Bacteria,1P0JQ@1224|Proteobacteria,2W3XG@28216|Betaproteobacteria,4AIBU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2533419_2	1198452.Jab_2c26000	4.758e-110	380.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VPAC@28216|Betaproteobacteria,4766N@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
ZZS3_k127_2533419_4	614083.AWQR01000005_gene1245	2.58e-60	220.0	COG0583@1|root,COG0583@2|Bacteria,1R785@1224|Proteobacteria,2VR27@28216|Betaproteobacteria,4AF8Q@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2533419_5	338969.Rfer_2774	1.101e-52	201.0	COG2867@1|root,COG2867@2|Bacteria,1RI5E@1224|Proteobacteria	1224|Proteobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
ZZS3_k127_2533419_3	365046.Rta_18760	3.341e-98	321.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2VKCH@28216|Betaproteobacteria,4A9VW@80864|Comamonadaceae	28216|Betaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
ZZS3_k127_257131_3	365046.Rta_14900	6.817e-120	396.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2VIKH@28216|Betaproteobacteria,4ACS2@80864|Comamonadaceae	28216|Betaproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
ZZS3_k127_257131_8	543728.Vapar_3206	1.36e-58	213.0	COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,2VUGI@28216|Betaproteobacteria,4AESZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	-	-	ko:K14160	-	-	-	-	ko00000,ko03400	-	-	-	-
ZZS3_k127_257131_0	365046.Rta_14870	7.489e-312	986.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VIAP@28216|Betaproteobacteria,4A9QF@80864|Comamonadaceae	28216|Betaproteobacteria	V	SMART AAA ATPase	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS3_k127_257131_7	365046.Rta_14860	1.506e-87	295.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,2VQAW@28216|Betaproteobacteria,4ADP6@80864|Comamonadaceae	28216|Betaproteobacteria	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
ZZS3_k127_257131_6	1532557.JL37_27170	2.064e-94	317.0	COG0697@1|root,COG0697@2|Bacteria,1N5ZD@1224|Proteobacteria,2VQCI@28216|Betaproteobacteria,3T3N6@506|Alcaligenaceae	28216|Betaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_257131_9	399795.CtesDRAFT_PD1505	5.787e-07	59.0	2E84Q@1|root,33CIE@2|Bacteria,1NKX2@1224|Proteobacteria,2VYB6@28216|Betaproteobacteria,4AG0Y@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_257131_1	1157708.KB907450_gene5203	1.996e-204	645.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VNZF@28216|Betaproteobacteria	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_257131_4	1123255.JHYS01000022_gene1461	5.198e-119	397.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2VII6@28216|Betaproteobacteria,4ABCU@80864|Comamonadaceae	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, B subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
ZZS3_k127_257131_2	1458275.AZ34_12060	7.111e-131	420.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2VHFT@28216|Betaproteobacteria,4AAV2@80864|Comamonadaceae	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
ZZS3_k127_257131_5	365046.Rta_14800	1.511e-103	338.0	COG2197@1|root,COG2197@2|Bacteria,1RAAY@1224|Proteobacteria,2VQ17@28216|Betaproteobacteria,4AAHC@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_9
ZZS3_k127_260031_9	365046.Rta_24650	1.084e-26	110.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,4ACYT@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM phasin family protein	phaP	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
ZZS3_k127_260031_7	296591.Bpro_3091	5.374e-112	371.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,4A9PX@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS3_k127_260031_3	365046.Rta_24660	2.269e-196	616.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,4AA3G@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM extracellular solute-binding protein family 1	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
ZZS3_k127_260031_5	1223521.BBJX01000004_gene2345	9.509e-140	446.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2VHU8@28216|Betaproteobacteria,4ABDR@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG3	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS3_k127_260031_0	365046.Rta_24680	1e-323	998.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VI60@28216|Betaproteobacteria,4A9Q2@80864|Comamonadaceae	28216|Betaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS3_k127_260031_6	296591.Bpro_3095	3.932e-129	419.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,4AAJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
ZZS3_k127_260031_4	1100720.ALKN01000045_gene319	1.628e-152	487.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,4A9W4@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_260031_1	1223521.BBJX01000012_gene551	2.191e-319	983.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,4ABQ5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_260031_2	365046.Rta_24700	2.138e-254	797.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,4AAB4@80864|Comamonadaceae	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
ZZS3_k127_260031_8	365046.Rta_24710	6.59e-102	344.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,4AAGE@80864|Comamonadaceae	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_2631886_7	365046.Rta_10960	6.34e-42	155.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,4ABAF@80864|Comamonadaceae	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_2631886_0	365046.Rta_10950	3.333e-230	724.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,4AAIX@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
ZZS3_k127_2631886_6	296591.Bpro_1637	3.953e-59	231.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,4AE0M@80864|Comamonadaceae	28216|Betaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
ZZS3_k127_2631886_3	365046.Rta_10930	1.804e-133	432.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,4A9YD@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_2631886_5	365044.Pnap_1706	3.332e-97	326.0	28M4Y@1|root,2ZAIT@2|Bacteria,1R7JR@1224|Proteobacteria,2VM7F@28216|Betaproteobacteria,4AD2S@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2631886_2	1298867.AUES01000089_gene2973	1.114e-145	470.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3K2G8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
ZZS3_k127_2631886_4	296591.Bpro_2276	2.253e-126	428.0	COG3181@1|root,COG3181@2|Bacteria,1R8HR@1224|Proteobacteria,2VZZ8@28216|Betaproteobacteria,4AH8U@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2631886_1	365046.Rta_29340	1.28e-194	610.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VP9T@28216|Betaproteobacteria,4ACDH@80864|Comamonadaceae	28216|Betaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_2667006_20	397945.Aave_3593	5.442e-17	80.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,4A9VQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
ZZS3_k127_2667006_8	535289.Dtpsy_0177	4.74e-115	385.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2VKMX@28216|Betaproteobacteria,4AATA@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_2667006_7	1458275.AZ34_07650	2.176e-117	385.0	COG0583@1|root,COG0583@2|Bacteria,1MV06@1224|Proteobacteria,2VHGD@28216|Betaproteobacteria,4AC1R@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2667006_21	1097668.BYI23_C008810	8.557e-15	84.0	2E1GC@1|root,32WUU@2|Bacteria,1N0XG@1224|Proteobacteria,2VX7K@28216|Betaproteobacteria,1K9JB@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2667006_17	365046.Rta_10370	2.155e-35	144.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Phenol_MetA_deg
ZZS3_k127_2667006_5	365044.Pnap_2143	2.869e-150	479.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2VIUS@28216|Betaproteobacteria,4AAUD@80864|Comamonadaceae	28216|Betaproteobacteria	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153,4.2.1.56	ko:K09709,ko:K18291	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R02491,R09282	RC00730,RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
ZZS3_k127_2667006_1	365046.Rta_16630	2.46e-239	741.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VKD1@28216|Betaproteobacteria,4AADX@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	acd12	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_2667006_2	365046.Rta_16640	7.213e-204	639.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2VKDA@28216|Betaproteobacteria,4AA04@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_2667006_24	1190606.AJYG01000100_gene1015	2.72e-05	47.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria,1Y1KV@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2667006_9	251221.35210937	3.504e-112	392.0	COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4
ZZS3_k127_2667006_10	1157708.KB907452_gene3679	1.295e-111	370.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2667006_4	365046.Rta_16100	3.03e-173	568.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,4AA5F@80864|Comamonadaceae	28216|Betaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
ZZS3_k127_2667006_12	365046.Rta_27450	2.914e-106	357.0	COG1286@1|root,COG2340@1|root,COG1286@2|Bacteria,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V,Trypsin_2
ZZS3_k127_2667006_23	1449065.JMLL01000011_gene2040	9.054e-07	60.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1Q86W@1224|Proteobacteria,2VECS@28211|Alphaproteobacteria,43NMW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
ZZS3_k127_2667006_19	1122185.N792_05440	3.499e-21	105.0	COG3861@1|root,COG3861@2|Bacteria,1MWBU@1224|Proteobacteria,1S1WP@1236|Gammaproteobacteria,1XCQG@135614|Xanthomonadales	135614|Xanthomonadales	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
ZZS3_k127_2667006_13	887062.HGR_00856	2.074e-90	309.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,4ABEW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
ZZS3_k127_2667006_0	365046.Rta_33000	0.0	1289.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,4AC5G@80864|Comamonadaceae	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
ZZS3_k127_2667006_15	365046.Rta_32990	1.062e-35	136.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,4AEWW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
ZZS3_k127_2667006_11	365046.Rta_32980	3.61e-108	352.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,4ABWZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
ZZS3_k127_2667006_25	870187.Thini_3172	5.705e-05	54.0	COG3409@1|root,COG3409@2|Bacteria,1NKQB@1224|Proteobacteria	1224|Proteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2667006_14	1123258.AQXZ01000018_gene569	1.338e-80	274.0	COG5549@1|root,COG5549@2|Bacteria,2I7P4@201174|Actinobacteria,4G4HZ@85025|Nocardiaceae	201174|Actinobacteria	O	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
ZZS3_k127_2667006_16	1032480.MLP_38400	1.943e-35	156.0	COG4249@1|root,COG4249@2|Bacteria,2GWHR@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2667006_18	1032480.MLP_38410	8.797e-29	135.0	2CFUR@1|root,33M72@2|Bacteria,2GXQH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2667006_6	365046.Rta_32960	2.075e-130	423.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,4AAC5@80864|Comamonadaceae	28216|Betaproteobacteria	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
ZZS3_k127_2667006_3	365046.Rta_32950	3.177e-202	631.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,4A9K1@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	spkD	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS3_k127_2719739_12	1157708.KB907458_gene1837	1.958e-33	129.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,4A9NT@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
ZZS3_k127_2719739_10	543728.Vapar_4131	1.085e-52	193.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,4AEBD@80864|Comamonadaceae	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hit	-	-	-	-	-	-	-	-	-	-	-	HIT
ZZS3_k127_2719739_4	614083.AWQR01000020_gene210	1.783e-153	497.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,2VWWI@28216|Betaproteobacteria,4AH9S@80864|Comamonadaceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
ZZS3_k127_2719739_3	946483.Cenrod_0212	8.71e-168	554.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2VHDS@28216|Betaproteobacteria,4A9SS@80864|Comamonadaceae	28216|Betaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	fhaC5	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
ZZS3_k127_2719739_9	365046.Rta_31240	6.215e-67	229.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,4ADW0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
ZZS3_k127_2719739_5	1276756.AUEX01000025_gene2064	4.852e-124	408.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,4AAFZ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
ZZS3_k127_2719739_6	365046.Rta_31220	6.158e-116	382.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,4A9J2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Import inner membrane translocase, subunit	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
ZZS3_k127_2719739_8	365046.Rta_31210	1.961e-74	255.0	COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,4AEN6@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
ZZS3_k127_2719739_0	365046.Rta_31200	6.849e-270	848.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,4A9ZQ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
ZZS3_k127_2719739_1	1123255.JHYS01000019_gene1738	1.743e-236	739.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,4AAXN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
ZZS3_k127_2719739_11	365046.Rta_31180	1.44e-44	164.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,4AEZ5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS3_k127_2719739_7	398578.Daci_5454	4.321e-98	325.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,4AB4A@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
ZZS3_k127_2719739_2	365046.Rta_31160	4.129e-227	705.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,4AB70@80864|Comamonadaceae	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
ZZS3_k127_2720613_6	1100720.ALKN01000028_gene2501	2.269e-31	124.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,4AC8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
ZZS3_k127_2720613_5	397945.Aave_4647	6.482e-80	269.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2VQ7U@28216|Betaproteobacteria,4ADNB@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
ZZS3_k127_2720613_1	381666.H16_A0369	1.916e-267	845.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2VK2V@28216|Betaproteobacteria,1K0C8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
ZZS3_k127_2720613_2	365046.Rta_37020	4.764e-189	598.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,4A9PK@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM MltA domain protein	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
ZZS3_k127_2720613_4	365046.Rta_37040	5.173e-83	307.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VK0C@28216|Betaproteobacteria,4AAKX@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator, receiver	-	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
ZZS3_k127_2720613_0	365046.Rta_37050	2.893e-286	901.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,4ABX9@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
ZZS3_k127_2720613_3	535289.Dtpsy_3367	5.001e-118	384.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,4ABAU@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
ZZS3_k127_2726682_16	365046.Rta_01710	8.448e-13	68.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VM54@28216|Betaproteobacteria,4AAA9@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
ZZS3_k127_2726682_10	365046.Rta_01710	9.76e-135	435.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VM54@28216|Betaproteobacteria,4AAA9@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
ZZS3_k127_2726682_4	365046.Rta_01700	1.447e-170	540.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,4A9R6@80864|Comamonadaceae	28216|Betaproteobacteria	H	Ketopantoate reductase	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
ZZS3_k127_2726682_9	365046.Rta_01670	2.265e-142	473.0	COG0697@1|root,COG0697@2|Bacteria,1MY34@1224|Proteobacteria,2VJYT@28216|Betaproteobacteria,4A9ZH@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_2726682_2	365046.Rta_01610	1.155e-207	649.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,4ABGQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
ZZS3_k127_2726682_0	365046.Rta_01600	4.215e-238	741.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,4A9Z8@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_2726682_13	365046.Rta_01590	1.313e-102	343.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,4AC11@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_2726682_14	360911.EAT1b_2564	2.589e-65	227.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli	91061|Bacilli	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
ZZS3_k127_2726682_5	358220.C380_01420	1.611e-167	552.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,2VP15@28216|Betaproteobacteria,4ACCQ@80864|Comamonadaceae	28216|Betaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ZZS3_k127_2726682_11	1458275.AZ34_01080	1.032e-114	376.0	COG3279@1|root,COG3279@2|Bacteria,1R90R@1224|Proteobacteria,2VPHS@28216|Betaproteobacteria,4ABN0@80864|Comamonadaceae	28216|Betaproteobacteria	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
ZZS3_k127_2726682_7	595537.Varpa_0024	2.748e-151	492.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,2VIXN@28216|Betaproteobacteria,4ABX1@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM Inner membrane CreD family protein	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
ZZS3_k127_2726682_3	365044.Pnap_0029	9.737e-203	641.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,4AB4V@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	creC	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
ZZS3_k127_2726682_12	614083.AWQR01000007_gene356	3.431e-111	365.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VQH1@28216|Betaproteobacteria,4ABPB@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_2726682_1	1123504.JQKD01000062_gene23	3.525e-218	700.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,4AAZ5@80864|Comamonadaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
ZZS3_k127_2726682_6	365046.Rta_01530	6.252e-155	497.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,4AAAA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_2726682_8	365046.Rta_01520	7.615e-143	464.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2VMAD@28216|Betaproteobacteria,4AARB@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
ZZS3_k127_2726682_15	614083.AWQR01000022_gene23	1.884e-37	143.0	COG2017@1|root,COG2017@2|Bacteria,1RGXX@1224|Proteobacteria,2VQB2@28216|Betaproteobacteria,4AJIG@80864|Comamonadaceae	28216|Betaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
ZZS3_k127_272730_2	365046.Rta_08100	6.949e-160	507.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,4ABRN@80864|Comamonadaceae	28216|Betaproteobacteria	E	glutamate synthase, alpha subunit domain protein	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
ZZS3_k127_272730_5	338969.Rfer_2932	8.426e-107	357.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,4AB1D@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
ZZS3_k127_272730_9	1157708.KB907450_gene6268	5.249e-17	82.0	2EGHT@1|root,33A9W@2|Bacteria,1NHZD@1224|Proteobacteria,2VXKV@28216|Betaproteobacteria,4AG19@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_272730_3	365046.Rta_08070	5.239e-137	447.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,2VH3B@28216|Betaproteobacteria,4ACAP@80864|Comamonadaceae	28216|Betaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
ZZS3_k127_272730_8	1123504.JQKD01000023_gene230	1.096e-61	224.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,2VQ9D@28216|Betaproteobacteria,4AA25@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
ZZS3_k127_272730_4	365046.Rta_08050	6.822e-134	455.0	COG2807@1|root,COG2807@2|Bacteria,1QU85@1224|Proteobacteria,2VNPC@28216|Betaproteobacteria,4AC7D@80864|Comamonadaceae	28216|Betaproteobacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_272730_0	365046.Rta_08040	1.875e-190	602.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,4AB16@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
ZZS3_k127_272730_1	1123504.JQKD01000023_gene233	4.324e-187	589.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,4AAFI@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
ZZS3_k127_272730_7	338969.Rfer_2925	6.782e-75	258.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,4ADJX@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
ZZS3_k127_272730_6	365046.Rta_08000	9.414e-89	293.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,4AB9A@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
ZZS3_k127_2731072_5	365046.Rta_21550	3.566e-75	254.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP7Y@28216|Betaproteobacteria,4ADPR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2731072_2	296591.Bpro_2789	6.137e-133	432.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,4ABTB@80864|Comamonadaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_2731072_3	887062.HGR_13034	2.737e-128	418.0	COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2VPZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Formyl transferase, C-terminal domain	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
ZZS3_k127_2731072_0	296591.Bpro_2790	3.49e-157	501.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,4ACPS@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2731072_6	296591.Bpro_2791	3.234e-17	83.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS3_k127_2731072_1	296591.Bpro_2793	7.996e-155	495.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,4ACG6@80864|Comamonadaceae	28216|Betaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
ZZS3_k127_2731072_4	296591.Bpro_2795	4.955e-99	326.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,4AC49@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2756988_7	365046.Rta_16030	4.316e-30	121.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2WEY5@28216|Betaproteobacteria,4AJAY@80864|Comamonadaceae	28216|Betaproteobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
ZZS3_k127_2756988_3	365046.Rta_16020	8.432e-166	527.0	COG1063@1|root,COG1063@2|Bacteria,1MUK8@1224|Proteobacteria,2W0EF@28216|Betaproteobacteria,4AGM5@80864|Comamonadaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_2756988_4	365046.Rta_16010	1.643e-148	482.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2VUT6@28216|Betaproteobacteria,4AJ4R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS3_k127_2756988_5	1254432.SCE1572_39735	5.815e-125	414.0	COG0438@1|root,COG0438@2|Bacteria,1Q3IF@1224|Proteobacteria,43794@68525|delta/epsilon subdivisions,2WTY0@28221|Deltaproteobacteria,2YWM7@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2756988_2	365046.Rta_15990	7.775e-180	584.0	COG4641@1|root,COG4641@2|Bacteria,1MY6E@1224|Proteobacteria,2VZFN@28216|Betaproteobacteria,4AH8Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ZZS3_k127_2756988_0	365046.Rta_15980	9.332e-195	621.0	COG4641@1|root,COG4641@2|Bacteria,1MXSZ@1224|Proteobacteria,2W1JH@28216|Betaproteobacteria,4AHHD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ZZS3_k127_2756988_1	365046.Rta_15970	7.338e-181	572.0	COG4641@1|root,COG4641@2|Bacteria,1N7WI@1224|Proteobacteria,2VZUX@28216|Betaproteobacteria,4AGT8@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ZZS3_k127_2756988_6	1366050.N234_04055	1.326e-95	321.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,1K30S@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS3_k127_2772082_7	1220589.CD32_09625	0.0006682	47.0	COG0500@1|root,COG2226@2|Bacteria,1TR6N@1239|Firmicutes,4ISTQ@91061|Bacilli,3IXVZ@400634|Lysinibacillus	91061|Bacilli	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
ZZS3_k127_2772082_0	365046.Rta_37120	0.0	1653.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS3_k127_2772082_4	365046.Rta_37110	1.253e-134	442.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,4AAUQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_2772082_3	365046.Rta_37100	1.691e-160	543.0	COG1538@1|root,COG1538@2|Bacteria,1P0S2@1224|Proteobacteria,2VH06@28216|Betaproteobacteria,4AAJB@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	tolC2	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS3_k127_2772082_2	365046.Rta_37080	0.0	1409.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,4A9PB@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
ZZS3_k127_2772082_1	365046.Rta_37070	0.0	1644.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,4ABZ1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
ZZS3_k127_2772082_5	1123504.JQKD01000006_gene1555	7.213e-127	412.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,4ABAU@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
ZZS3_k127_2772082_6	365046.Rta_37050	2.904e-103	351.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,4ABX9@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
ZZS3_k127_2790819_1	365046.Rta_27110	1.518e-121	394.0	COG3181@1|root,COG3181@2|Bacteria,1R6C7@1224|Proteobacteria,2VK24@28216|Betaproteobacteria,4ACTF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2790819_5	395494.Galf_0088	1.115e-45	170.0	COG0607@1|root,COG0607@2|Bacteria,1RKRX@1224|Proteobacteria,2VTV2@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd,Rhodanese
ZZS3_k127_2790819_3	29581.BW37_00650	2.666e-96	336.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,476K0@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	PFAM HAMP domain, Methyl-accepting chemotaxis protein (MCP) signaling domain	tsr	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3
ZZS3_k127_2790819_2	1007105.PT7_1585	2.94e-104	349.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2WEIA@28216|Betaproteobacteria,3T9AH@506|Alcaligenaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2790819_0	365046.Rta_27130	1.304e-192	614.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VM6J@28216|Betaproteobacteria,4AJ1N@80864|Comamonadaceae	28216|Betaproteobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
ZZS3_k127_2790819_4	365046.Rta_21530	3.494e-93	310.0	COG1802@1|root,COG1802@2|Bacteria,1RGF0@1224|Proteobacteria,2VSB3@28216|Betaproteobacteria,4ADPY@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_279108_2	543728.Vapar_0147	3.817e-232	720.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,4AB7Z@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
ZZS3_k127_279108_7	266264.Rmet_3552	3.234e-31	141.0	COG2050@1|root,COG2050@2|Bacteria,1MYM3@1224|Proteobacteria,2VTF1@28216|Betaproteobacteria,1K7CY@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_279108_4	365046.Rta_01290	3.45e-197	621.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VKC7@28216|Betaproteobacteria,4ABMY@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
ZZS3_k127_279108_0	365046.Rta_01300	0.0	1356.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,2VK2M@28216|Betaproteobacteria,4AAN6@80864|Comamonadaceae	28216|Betaproteobacteria	O	AAA ATPase, central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
ZZS3_k127_279108_1	365046.Rta_01330	0.0	1003.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,4AAFA@80864|Comamonadaceae	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
ZZS3_k127_279108_3	365046.Rta_01340	7.65e-198	619.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2VJ2K@28216|Betaproteobacteria,4AAEB@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM homocysteine S-methyltransferase	metHa	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
ZZS3_k127_279108_5	365046.Rta_23250	1.156e-116	386.0	COG0265@1|root,COG0265@2|Bacteria,1N58P@1224|Proteobacteria,2VS6N@28216|Betaproteobacteria,4AHSM@80864|Comamonadaceae	28216|Betaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_279108_6	1268622.AVS7_04685	2.514e-76	257.0	COG1522@1|root,COG1522@2|Bacteria,1RC2H@1224|Proteobacteria,2VQIH@28216|Betaproteobacteria,4ADR5@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
ZZS3_k127_279828_0	296591.Bpro_2805	0.0	1520.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,4AAQA@80864|Comamonadaceae	28216|Betaproteobacteria	C	formate dehydrogenase, alpha subunit	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
ZZS3_k127_279828_11	864051.BurJ1DRAFT_0227	7.147e-106	347.0	COG5514@1|root,COG5514@2|Bacteria,1MX90@1224|Proteobacteria,2VIMN@28216|Betaproteobacteria,1KKIT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
ZZS3_k127_279828_6	535289.Dtpsy_1728	2.428e-140	455.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,4A9YH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular liganD-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_279828_2	196367.JNFG01000008_gene6553	2.18e-272	859.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KGEM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
ZZS3_k127_279828_3	1121127.JAFA01000046_gene6827	1.598e-197	627.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2VZP3@28216|Betaproteobacteria,1KHJR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
ZZS3_k127_279828_10	204669.Acid345_0843	2.415e-116	403.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y3JK@57723|Acidobacteria,2JIZX@204432|Acidobacteriia	204432|Acidobacteriia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
ZZS3_k127_279828_7	1349767.GJA_5345	1.181e-131	433.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2VHJW@28216|Betaproteobacteria,475ZN@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS3_k127_279828_4	1500890.JQNL01000001_gene828	1.152e-151	501.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X57C@135614|Xanthomonadales	135614|Xanthomonadales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_279828_18	1458275.AZ34_11490	7.308e-20	96.0	2ECQP@1|root,336ND@2|Bacteria,1N8WQ@1224|Proteobacteria,2VWZM@28216|Betaproteobacteria,4AFPN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4148
ZZS3_k127_279828_12	196367.JNFG01000008_gene6551	3.295e-80	273.0	COG4566@1|root,COG4566@2|Bacteria,1RAWG@1224|Proteobacteria,2WEM4@28216|Betaproteobacteria,1K7J4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_279828_17	1033802.SSPSH_001412	2.484e-23	108.0	28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,1S45N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_279828_15	204669.Acid345_0841	7.097e-55	199.0	COG0251@1|root,COG0251@2|Bacteria,3Y4XC@57723|Acidobacteria,2JMY3@204432|Acidobacteriia	204432|Acidobacteriia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
ZZS3_k127_279828_1	1123073.KB899241_gene2368	1.813e-307	964.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1X5E5@135614|Xanthomonadales	135614|Xanthomonadales	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS3_k127_279828_14	1038860.AXAP01000012_gene1247	8.258e-70	247.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,3JWTY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
ZZS3_k127_279828_13	1267535.KB906767_gene1911	5.237e-78	267.0	COG4566@1|root,COG4566@2|Bacteria,3Y4GS@57723|Acidobacteria,2JJ1Z@204432|Acidobacteriia	204432|Acidobacteriia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_279828_8	1265502.KB905933_gene2095	1.383e-122	414.0	COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2VID6@28216|Betaproteobacteria,4AA8T@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM ABC transporter related	rbsA	-	-	ko:K10554	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	ABC_tran
ZZS3_k127_279828_5	358220.C380_20400	1.525e-148	493.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VJ3R@28216|Betaproteobacteria,4ABTD@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10553	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	BPD_transp_2
ZZS3_k127_279828_9	864051.BurJ1DRAFT_0217	1.854e-117	385.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VJFU@28216|Betaproteobacteria,1KK9G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
ZZS3_k127_2801115_2	296591.Bpro_4500	6.038e-158	503.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4A9YS@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K21393	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctM
ZZS3_k127_2801115_0	1458275.AZ34_08305	3.687e-179	566.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,4A9T2@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
ZZS3_k127_2801115_5	748280.NH8B_2504	2.563e-73	250.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,2KR78@206351|Neisseriales	206351|Neisseriales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
ZZS3_k127_2801115_4	887062.HGR_15394	9.568e-134	439.0	COG0169@1|root,COG0169@2|Bacteria,1MVW5@1224|Proteobacteria,2VJU3@28216|Betaproteobacteria,4A9XV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Shikimate dehydrogenase substrate binding domain protein	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N,ThiF
ZZS3_k127_2801115_3	887062.HGR_15389	3.623e-147	473.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2VHYD@28216|Betaproteobacteria,4ACG3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
ZZS3_k127_2801115_1	887062.HGR_15384	3.674e-161	526.0	COG1082@1|root,COG1082@2|Bacteria,1QYE4@1224|Proteobacteria,2VJQ6@28216|Betaproteobacteria,4ABF5@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS3_k127_2818043_0	358220.C380_20975	3.481e-246	766.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VH8F@28216|Betaproteobacteria,4ACD0@80864|Comamonadaceae	28216|Betaproteobacteria	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
ZZS3_k127_2818043_10	358220.C380_20980	1.933e-99	328.0	COG1280@1|root,COG1280@2|Bacteria,1RARZ@1224|Proteobacteria,2WFMJ@28216|Betaproteobacteria,4AJSY@80864|Comamonadaceae	28216|Betaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
ZZS3_k127_2818043_6	365046.Rta_05400	1.506e-143	492.0	COG0697@1|root,COG0697@2|Bacteria,1MVHN@1224|Proteobacteria,2VI21@28216|Betaproteobacteria,4AD5E@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_2818043_1	365046.Rta_05390	8.94e-188	609.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,4A9JE@80864|Comamonadaceae	28216|Betaproteobacteria	EK	PFAM aminotransferase, class I and II	lysN	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
ZZS3_k127_2818043_11	365046.Rta_05380	3.793e-92	307.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,2VQHN@28216|Betaproteobacteria,4AAGD@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
ZZS3_k127_2818043_5	365046.Rta_05370	2.891e-151	493.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2VHM0@28216|Betaproteobacteria,4ABI5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phenazine biosynthesis protein phzf family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
ZZS3_k127_2818043_12	365046.Rta_05360	1.921e-91	305.0	COG0346@1|root,COG0346@2|Bacteria,1RD81@1224|Proteobacteria,2VQA3@28216|Betaproteobacteria,4ADJ6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
ZZS3_k127_2818043_14	595537.Varpa_0759	2.729e-81	292.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VKUK@28216|Betaproteobacteria,4ABR1@80864|Comamonadaceae	28216|Betaproteobacteria	E	Lysine exporter protein (Lyse ygga)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
ZZS3_k127_2818043_8	365046.Rta_05320	5.638e-116	377.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,2VJR8@28216|Betaproteobacteria,4AABW@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ZZS3_k127_2818043_7	358220.C380_22605	2.84e-119	399.0	COG0642@1|root,COG0642@2|Bacteria,1R4WN@1224|Proteobacteria,2VJA6@28216|Betaproteobacteria,4ABR2@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HisKA
ZZS3_k127_2818043_13	296591.Bpro_4632	1.616e-90	304.0	COG0745@1|root,COG0745@2|Bacteria,1NV31@1224|Proteobacteria,2VJ12@28216|Betaproteobacteria,4AAH5@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_2818043_16	232721.Ajs_1873	3.227e-69	241.0	COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,2VQKI@28216|Betaproteobacteria,4ADPN@80864|Comamonadaceae	28216|Betaproteobacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
ZZS3_k127_2818043_2	1504672.669786277	1.197e-170	565.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2VJHS@28216|Betaproteobacteria,4AA9C@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Sulfatase	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
ZZS3_k127_2818043_19	1276756.AUEX01000030_gene204	1.013e-28	132.0	COG0526@1|root,COG0526@2|Bacteria,1N8B0@1224|Proteobacteria,2VW5T@28216|Betaproteobacteria,4AEW1@80864|Comamonadaceae	28216|Betaproteobacteria	CO	PFAM Thioredoxin	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Thioredoxin
ZZS3_k127_2818043_20	365046.Rta_05280	2.646e-22	107.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,2VY5U@28216|Betaproteobacteria,4AFHJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
ZZS3_k127_2818043_15	1157708.KB907452_gene3631	3.925e-80	269.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2VQ5F@28216|Betaproteobacteria,4ADMK@80864|Comamonadaceae	28216|Betaproteobacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
ZZS3_k127_2818043_18	1298863.AUEP01000011_gene635	8.107e-36	143.0	COG1158@1|root,COG1158@2|Bacteria,2IKUK@201174|Actinobacteria,4DR4P@85009|Propionibacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2818043_17	365046.Rta_05260	4.689e-59	213.0	COG0517@1|root,COG0517@2|Bacteria,1QTWY@1224|Proteobacteria,2VTYW@28216|Betaproteobacteria,4AF94@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS3_k127_2818043_4	365046.Rta_05240	1.351e-158	525.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VKMD@28216|Betaproteobacteria,4ADAD@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81	ko:K00032,ko:K00090	ko00030,ko00260,ko00480,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00480,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R01739,R02032,R02034	RC00001,RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_2818043_3	365046.Rta_05230	9.058e-169	546.0	COG0524@1|root,COG0524@2|Bacteria,1MV6I@1224|Proteobacteria,2VM9T@28216|Betaproteobacteria,4AB2C@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
ZZS3_k127_2818043_9	365046.Rta_05220	1.616e-112	366.0	COG1082@1|root,COG1082@2|Bacteria,1MVBP@1224|Proteobacteria,2VMTH@28216|Betaproteobacteria,4ACEM@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS3_k127_2824439_12	365046.Rta_35420	9.822e-63	218.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AAST@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS3_k127_2824439_0	365046.Rta_35410	2.477e-296	924.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria,4AA7Z@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
ZZS3_k127_2824439_5	365046.Rta_35400	1.28e-100	334.0	28IWK@1|root,2Z8UV@2|Bacteria,1P9EC@1224|Proteobacteria,2VJZY@28216|Betaproteobacteria,4A9V5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Type II secretion system (T2SS), protein N	gspN	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
ZZS3_k127_2824439_13	365046.Rta_35390	3.951e-46	186.0	COG3149@1|root,COG3149@2|Bacteria,1N133@1224|Proteobacteria,2VUUD@28216|Betaproteobacteria,4AF13@80864|Comamonadaceae	28216|Betaproteobacteria	U	Type II secretion system (T2SS), protein M	gspM	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
ZZS3_k127_2824439_4	365046.Rta_35380	3.015e-146	475.0	COG3297@1|root,COG3297@2|Bacteria,1MX9I@1224|Proteobacteria,2VH8V@28216|Betaproteobacteria,4AAUV@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM General secretion pathway L	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
ZZS3_k127_2824439_6	365046.Rta_35370	2.658e-100	347.0	COG3156@1|root,COG3156@2|Bacteria,1RE52@1224|Proteobacteria,2WFQK@28216|Betaproteobacteria,4AJT6@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
ZZS3_k127_2824439_7	365046.Rta_35360	4.674e-80	280.0	COG4968@1|root,COG4968@2|Bacteria,1QZE6@1224|Proteobacteria,2WHKX@28216|Betaproteobacteria,4AJZR@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
ZZS3_k127_2824439_14	232721.Ajs_0673	1.581e-44	171.0	COG4967@1|root,COG4967@2|Bacteria,1QVHW@1224|Proteobacteria,2VVZP@28216|Betaproteobacteria,4AECE@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein I J	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
ZZS3_k127_2824439_11	1276756.AUEX01000016_gene1861	1.721e-71	255.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria,4ADIE@80864|Comamonadaceae	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
ZZS3_k127_2824439_15	358220.C380_03855	1.263e-33	148.0	2DP58@1|root,32UKC@2|Bacteria,1N8RA@1224|Proteobacteria,2VW6I@28216|Betaproteobacteria,4AFWZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	general secretion pathway protein	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
ZZS3_k127_2824439_16	365046.Rta_35310	2.732e-33	138.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2VJR1@28216|Betaproteobacteria,4AACR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
ZZS3_k127_2824439_1	365046.Rta_35300	1.159e-290	905.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,4ABVC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
ZZS3_k127_2824439_10	365046.Rta_35290	6.887e-73	252.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,4ADIX@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
ZZS3_k127_2824439_9	365044.Pnap_0646	1.848e-76	269.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,4ADF7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
ZZS3_k127_2824439_3	365046.Rta_35270	7.93e-148	476.0	COG3203@1|root,COG3203@2|Bacteria,1R5T2@1224|Proteobacteria,2VMH6@28216|Betaproteobacteria,4ACZH@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM porin Gram-negative type	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
ZZS3_k127_2824439_8	296591.Bpro_0748	2.7e-79	277.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,2VRDD@28216|Betaproteobacteria,4AENK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
ZZS3_k127_2824439_2	1100721.ALKO01000017_gene1795	1.798e-243	759.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,4ABBW@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_2838963_2	1123504.JQKD01000005_gene4753	1.233e-136	441.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHME@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2838963_1	1123060.JONP01000007_gene5140	3.022e-162	521.0	COG0329@1|root,COG0329@2|Bacteria,1MWMN@1224|Proteobacteria,2TSAF@28211|Alphaproteobacteria,2JV2K@204441|Rhodospirillales	204441|Rhodospirillales	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
ZZS3_k127_2838963_3	1038859.AXAU01000003_gene5977	9.352e-136	440.0	COG0451@1|root,COG0451@2|Bacteria,1MWQ2@1224|Proteobacteria,2TTJ2@28211|Alphaproteobacteria,3JWEI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	GM	NAD dependent epimerase/dehydratase family	MA20_28780	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ZZS3_k127_2838963_0	365046.Rta_13170	2.266e-287	892.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2VHSM@28216|Betaproteobacteria,4ACBD@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	rosB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
ZZS3_k127_2838963_5	1336243.JAEA01000006_gene517	5.118e-66	239.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VFVM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS3_k127_2838963_4	365046.Rta_13120	1.48e-91	301.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,4ABCI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_2848933_5	1123504.JQKD01000020_gene5639	4.525e-56	196.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,4AAR9@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_2848933_2	688245.CtCNB1_1161	6.471e-119	389.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,2VK5H@28216|Betaproteobacteria,4ABK4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_2848933_4	365046.Rta_25690	4.219e-81	273.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2WGK0@28216|Betaproteobacteria,4ADYH@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
ZZS3_k127_2848933_1	596153.Alide_1102	2.528e-170	537.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,4A9Y6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS3_k127_2848933_0	365046.Rta_25710	1.701e-178	564.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,4ABTG@80864|Comamonadaceae	28216|Betaproteobacteria	M	Nlpbdapx family lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
ZZS3_k127_2848933_3	365046.Rta_25720	5.724e-118	383.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,4ABYS@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS3_k127_2895522_1	365046.Rta_36310	4.811e-226	724.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,4AB5P@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
ZZS3_k127_2895522_3	365046.Rta_36280	8.198e-183	576.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,4ACTD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
ZZS3_k127_2895522_0	365046.Rta_36270	0.0	1101.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,4A9JQ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
ZZS3_k127_2895522_2	365046.Rta_36260	7.577e-187	586.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,4A9KZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2895522_7	748247.AZKH_1688	8.198e-96	337.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,2VKMS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Dyp-type peroxidase family	dyp	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
ZZS3_k127_2895522_4	338969.Rfer_3680	5.588e-132	441.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,4AA51@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
ZZS3_k127_2895522_5	296591.Bpro_0475	1.907e-119	393.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,4A9WJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
ZZS3_k127_2895522_6	1157708.KB907451_gene5003	8.537e-103	341.0	COG4222@1|root,COG4222@2|Bacteria,1R88V@1224|Proteobacteria,2VJAB@28216|Betaproteobacteria,4AD5Q@80864|Comamonadaceae	28216|Betaproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
ZZS3_k127_2946070_4	365046.Rta_21240	5.392e-23	98.0	COG0807@1|root,COG0807@2|Bacteria,1MWUM@1224|Proteobacteria,2VJRX@28216|Betaproteobacteria,4AC3M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Protein of unknown function (DUF1688)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1688
ZZS3_k127_2946070_2	365046.Rta_21250	2.219e-117	379.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2VKM0@28216|Betaproteobacteria,4AACN@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
ZZS3_k127_2946070_1	296591.Bpro_1962	1.101e-136	448.0	COG0457@1|root,COG0457@2|Bacteria,1RAPH@1224|Proteobacteria,2VPDH@28216|Betaproteobacteria,4AJWC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2946070_0	365046.Rta_21270	3.316e-156	520.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,4ADQY@80864|Comamonadaceae	28216|Betaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
ZZS3_k127_2946070_3	365046.Rta_21290	3.616e-106	347.0	COG1744@1|root,COG1744@2|Bacteria,1MVU5@1224|Proteobacteria,2VKZI@28216|Betaproteobacteria,4AC38@80864|Comamonadaceae	28216|Betaproteobacteria	M	Basic membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
ZZS3_k127_2949135_8	571166.KI421509_gene4103	3.123e-84	284.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,2TTCA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0076 Glutamate decarboxylase and related PLP-dependent proteins	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
ZZS3_k127_2949135_2	296591.Bpro_3695	9.515e-122	400.0	COG2010@1|root,COG2010@2|Bacteria,1MXXQ@1224|Proteobacteria,2VNJS@28216|Betaproteobacteria,4ACUW@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_2949135_3	365046.Rta_13970	1.927e-111	371.0	COG1414@1|root,COG1414@2|Bacteria,1R7X4@1224|Proteobacteria,2VN5Y@28216|Betaproteobacteria,4ABI8@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_2949135_0	365046.Rta_13960	2.504e-148	481.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VH3X@28216|Betaproteobacteria,4AAQB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2949135_4	365046.Rta_13950	3.831e-107	368.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2VM9Z@28216|Betaproteobacteria,4AC7U@80864|Comamonadaceae	28216|Betaproteobacteria	H	Dimethylmenaquinone methyltransferase	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
ZZS3_k127_2949135_1	596153.Alide_0349	9.397e-136	451.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2VIFQ@28216|Betaproteobacteria,4ACGC@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_2949135_12	743720.Psefu_0914	1.006e-15	81.0	COG1278@1|root,COG1278@2|Bacteria,1N1M6@1224|Proteobacteria,1S9AQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM Excalibur calcium-binding domain	cspC	-	-	-	-	-	-	-	-	-	-	-	CSD,Excalibur
ZZS3_k127_2949135_9	365046.Rta_16930	1.092e-80	283.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria,4ACXC@80864|Comamonadaceae	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
ZZS3_k127_2949135_6	1276756.AUEX01000010_gene1611	1.382e-87	297.0	COG2267@1|root,COG2267@2|Bacteria,1MWHN@1224|Proteobacteria,2VI1B@28216|Betaproteobacteria,4ABV6@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_2949135_13	118168.MC7420_1471	0.0001074	55.0	COG0457@1|root,COG0457@2|Bacteria,1G25M@1117|Cyanobacteria,1H9FA@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
ZZS3_k127_2949135_7	596153.Alide_0778	9.385e-86	294.0	COG1876@1|root,COG1876@2|Bacteria,1NAYN@1224|Proteobacteria,2VW00@28216|Betaproteobacteria	28216|Betaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M15_4,VanY
ZZS3_k127_2949135_5	247490.KSU1_B0586	2.364e-98	334.0	COG1404@1|root,COG1404@2|Bacteria,2J3V6@203682|Planctomycetes	203682|Planctomycetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS3_k127_2949135_11	1380355.JNIJ01000051_gene2203	5.425e-53	196.0	2DNBY@1|root,32WPF@2|Bacteria,1QX1S@1224|Proteobacteria,2UGXK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2949135_10	365046.Rta_16960	4.81e-66	228.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_2967899_1	296591.Bpro_2940	6.565e-129	413.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,4A9M9@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS3_k127_2967899_2	296591.Bpro_2927	2.183e-78	264.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,4AE5E@80864|Comamonadaceae	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
ZZS3_k127_2967899_3	1122185.N792_05440	1.667e-49	196.0	COG3861@1|root,COG3861@2|Bacteria,1MWBU@1224|Proteobacteria,1S1WP@1236|Gammaproteobacteria,1XCQG@135614|Xanthomonadales	135614|Xanthomonadales	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
ZZS3_k127_2967899_0	1458357.BG58_08745	5.406e-184	588.0	COG0148@1|root,COG0148@2|Bacteria,1PIEJ@1224|Proteobacteria,2W0R9@28216|Betaproteobacteria,1K309@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
ZZS3_k127_2967899_4	358823.DF19_29365	1.416e-19	91.0	COG4857@1|root,COG4857@2|Bacteria,2INGW@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
ZZS3_k127_2985280_1	365046.Rta_16530	3.434e-174	556.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,4ACGT@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	nodT	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS3_k127_2985280_5	296591.Bpro_1181	2.006e-17	87.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2985280_3	365046.Rta_16580	1.425e-103	355.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,4AA3R@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
ZZS3_k127_2985280_4	1504672.669786966	1.304e-94	318.0	COG0583@1|root,COG0583@2|Bacteria,1R9N4@1224|Proteobacteria,2VPWQ@28216|Betaproteobacteria,4AC9P@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_2985280_2	365046.Rta_16670	5.029e-163	518.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM3I@28216|Betaproteobacteria,4AB0D@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_2985280_0	365046.Rta_16680	1.512e-294	927.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VH8Z@28216|Betaproteobacteria,4AB1S@80864|Comamonadaceae	28216|Betaproteobacteria	E	gamma-glutamyltransferase	ggt1	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS3_k127_3052423_0	296591.Bpro_1638	1.438e-240	752.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,4AAIX@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
ZZS3_k127_3052423_4	1187851.A33M_1661	1.508e-106	358.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,3FCJH@34008|Rhodovulum	1224|Proteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS3_k127_3052423_1	395495.Lcho_2443	3.681e-196	621.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KIW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_3052423_3	365046.Rta_10970	5.544e-148	474.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,4ACVZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaC	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS3_k127_3052423_2	365046.Rta_10980	7.971e-181	590.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,4A9ND@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
ZZS3_k127_3091803_6	365046.Rta_08530	3.907e-129	419.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,4A9TD@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
ZZS3_k127_3091803_8	365046.Rta_08520	9.032e-113	371.0	COG2197@1|root,COG2197@2|Bacteria,1NN5P@1224|Proteobacteria,2WBD7@28216|Betaproteobacteria,4AHFF@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ZZS3_k127_3091803_4	365046.Rta_08510	3.296e-138	470.0	COG0642@1|root,COG2205@2|Bacteria,1QY4M@1224|Proteobacteria	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS3_k127_3091803_5	365046.Rta_08500	5.994e-133	431.0	COG2201@1|root,COG2201@2|Bacteria,1QUZP@1224|Proteobacteria	1224|Proteobacteria	NT	Response regulator receiver domain	jqsR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_3091803_1	296591.Bpro_4048	1.599e-186	592.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VNA4@28216|Betaproteobacteria,4AJ1H@80864|Comamonadaceae	28216|Betaproteobacteria	H	Aminotransferase class I and II	jqsA	-	-	ko:K10915	ko02024,ko05111,map02024,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
ZZS3_k127_3091803_0	365046.Rta_08480	0.0	1572.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,4A9XE@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
ZZS3_k127_3091803_3	365046.Rta_08470	4.936e-143	461.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,4AAYI@80864|Comamonadaceae	28216|Betaproteobacteria	M	Peptidase M23B	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
ZZS3_k127_3091803_9	365046.Rta_08465	2.466e-35	137.0	COG4701@1|root,COG4701@2|Bacteria,1N5G9@1224|Proteobacteria,2VU6Y@28216|Betaproteobacteria,4AEVQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
ZZS3_k127_3091803_7	94624.Bpet2878	1.157e-117	385.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2VQIG@28216|Betaproteobacteria,3T5BR@506|Alcaligenaceae	28216|Betaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ZZS3_k127_3091803_2	614083.AWQR01000012_gene1344	7.186e-155	491.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VNGY@28216|Betaproteobacteria,4ADCT@80864|Comamonadaceae	28216|Betaproteobacteria	C	Phenol hydroxylase, C-terminal dimerisation domain	-	-	1.14.13.23,1.14.13.7	ko:K03380,ko:K19065	ko00362,ko00623,ko00624,ko00627,ko01120,ko01220,map00362,map00623,map00624,map00627,map01120,map01220	-	R00815,R01628,R03566	RC00046,RC00236	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Phe_hydrox_dim
ZZS3_k127_3108527_1	1276756.AUEX01000005_gene2662	0.0	1086.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,4AAB5@80864|Comamonadaceae	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
ZZS3_k127_3108527_11	365046.Rta_02450	9.338e-167	529.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,4AAM5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
ZZS3_k127_3108527_13	365046.Rta_02470	8.29e-156	494.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,2VJP1@28216|Betaproteobacteria,4AC4S@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Glutamine amidotransferase, class-II	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
ZZS3_k127_3108527_4	1157708.KB907455_gene3373	6.079e-220	698.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VIFY@28216|Betaproteobacteria,4AA7H@80864|Comamonadaceae	28216|Betaproteobacteria	P	Major facilitator superfamily	lmrB	-	-	ko:K03446,ko:K18926	-	M00701,M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3,2.A.1.3.30	-	-	MFS_1
ZZS3_k127_3108527_28	365046.Rta_02495	3.225e-22	102.0	2CA5H@1|root,33A7N@2|Bacteria,1NI9X@1224|Proteobacteria,2VXS5@28216|Betaproteobacteria,4AFW0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
ZZS3_k127_3108527_14	296591.Bpro_4528	6.112e-153	511.0	COG1231@1|root,COG1231@2|Bacteria,1NVGR@1224|Proteobacteria,2VJU0@28216|Betaproteobacteria,4AB24@80864|Comamonadaceae	28216|Betaproteobacteria	E	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
ZZS3_k127_3108527_0	365046.Rta_02700	0.0	1259.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJMS@28216|Betaproteobacteria,4AB06@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
ZZS3_k127_3108527_17	543728.Vapar_0453	2.755e-112	365.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,2VI7A@28216|Betaproteobacteria,4AD0W@80864|Comamonadaceae	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like)	dhlB	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
ZZS3_k127_3108527_6	365046.Rta_02710	1.531e-199	624.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2VV9X@28216|Betaproteobacteria,4AEXH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
ZZS3_k127_3108527_12	365046.Rta_02720	1.46e-166	546.0	COG3181@1|root,COG3181@2|Bacteria,1N00G@1224|Proteobacteria,2VN46@28216|Betaproteobacteria,4AJ0G@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3108527_19	1205680.CAKO01000029_gene5137	9.004e-78	292.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2U5C5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_3,GST_N_3
ZZS3_k127_3108527_7	365046.Rta_02730	8.159e-199	642.0	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2VJB6@28216|Betaproteobacteria,4AAJC@80864|Comamonadaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_3108527_10	365046.Rta_02760	1.631e-175	553.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VJ8W@28216|Betaproteobacteria,4ACID@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	dmlR2	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_3108527_23	365046.Rta_02770	3.271e-57	202.0	COG3556@1|root,COG3556@2|Bacteria,1N3XH@1224|Proteobacteria,2VRQ4@28216|Betaproteobacteria,4AE2D@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
ZZS3_k127_3108527_2	365046.Rta_02780	6.157e-320	983.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,4AACX@80864|Comamonadaceae	28216|Betaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ZZS3_k127_3108527_22	365046.Rta_02790	1.567e-61	239.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,4ADFH@80864|Comamonadaceae	28216|Betaproteobacteria	D	PFAM Sporulation domain protein	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
ZZS3_k127_3108527_18	365046.Rta_02800	7.59e-79	269.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,4ADS0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin
ZZS3_k127_3108527_21	1504672.669785452	7.143e-64	244.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,4ADFD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
ZZS3_k127_3108527_16	365046.Rta_02820	1.954e-129	430.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,4ABQP@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC transporter related	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_3108527_3	365046.Rta_02830	9.216e-235	736.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,4A9UF@80864|Comamonadaceae	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
ZZS3_k127_3108527_8	365046.Rta_02840	1.267e-191	605.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,4AB1A@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
ZZS3_k127_3108527_26	296591.Bpro_4483	3.25e-39	151.0	COG1569@1|root,COG1569@2|Bacteria,1NASM@1224|Proteobacteria,2VVUB@28216|Betaproteobacteria,4AF1G@80864|Comamonadaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
ZZS3_k127_3108527_24	365046.Rta_36010	5.02e-54	213.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,4AE14@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
ZZS3_k127_3108527_20	1219031.BBJR01000051_gene1490	1.269e-75	257.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,4ADZU@80864|Comamonadaceae	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
ZZS3_k127_3108527_25	365046.Rta_35990	1.744e-39	154.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria,4AF2V@80864|Comamonadaceae	28216|Betaproteobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
ZZS3_k127_3108527_15	365046.Rta_35980	1.237e-141	455.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,4AABK@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS3_k127_3108527_5	365046.Rta_35950	6.696e-206	647.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria,4AAIT@80864|Comamonadaceae	28216|Betaproteobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
ZZS3_k127_3108527_9	365046.Rta_35940	2.367e-191	604.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,2VKV2@28216|Betaproteobacteria,4AA1N@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
ZZS3_k127_3108527_27	365046.Rta_35920	3.591e-38	143.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,4AEBK@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
ZZS3_k127_3134105_2	365046.Rta_07970	3.542e-76	276.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,4AAVZ@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
ZZS3_k127_3134105_1	365046.Rta_07960	9.191e-197	617.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,4ABBB@80864|Comamonadaceae	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS3_k127_3134105_0	365046.Rta_07950	0.0	1316.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,4AA8D@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
ZZS3_k127_3134105_3	365046.Rta_07940	1.676e-32	127.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,4AEII@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the frataxin family	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
ZZS3_k127_319811_1	365046.Rta_12270	1.529e-226	706.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,4AAJM@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	TIGRFAM Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
ZZS3_k127_319811_3	556268.OFAG_01394	1.706e-200	632.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,478KW@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS3_k127_319811_11	596153.Alide_0081	4.68e-12	70.0	COG0583@1|root,COG0583@2|Bacteria,1R9E9@1224|Proteobacteria,2VPZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_319811_9	477184.KYC_25618	1.13e-115	379.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2VJCD@28216|Betaproteobacteria,3T28N@506|Alcaligenaceae	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_319811_0	1003200.AXXA_07400	5.479e-256	796.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldA	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_319811_5	1392838.AWNM01000016_gene3335	7.528e-184	586.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria	1224|Proteobacteria	M	Nad-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS3_k127_319811_6	1216976.AX27061_5507	9.539e-129	418.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP7Y@28216|Betaproteobacteria,3T3E1@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_319811_7	1392838.AWNM01000016_gene3338	9.7e-126	426.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_319811_10	477184.KYC_25588	7.373e-85	304.0	COG0684@1|root,COG0684@2|Bacteria,1RB88@1224|Proteobacteria,2VW44@28216|Betaproteobacteria,3T5WF@506|Alcaligenaceae	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ZZS3_k127_319811_8	1392838.AWNM01000016_gene3340	1.179e-122	400.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VIVP@28216|Betaproteobacteria,3T21H@506|Alcaligenaceae	28216|Betaproteobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_319811_4	1003200.AXXA_06653	3.467e-185	593.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,3T2CQ@506|Alcaligenaceae	28216|Betaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_319811_2	1223521.BBJX01000002_gene2856	1.529e-226	706.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VHBI@28216|Betaproteobacteria,4AGVV@80864|Comamonadaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_3201329_5	391735.Veis_0081	2.365e-09	59.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,4AE06@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
ZZS3_k127_3201329_0	365046.Rta_18940	1.834e-248	769.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,4AB64@80864|Comamonadaceae	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
ZZS3_k127_3201329_1	365046.Rta_18950	1.239e-232	732.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,4A9P9@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
ZZS3_k127_3201329_3	365046.Rta_18960	3.984e-91	306.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,4ADK6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
ZZS3_k127_3201329_2	365046.Rta_18970	5.938e-155	509.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,4A9WS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
ZZS3_k127_3201329_4	358220.C380_08410	1.409e-57	202.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,4ACK5@80864|Comamonadaceae	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
ZZS3_k127_3235708_8	365046.Rta_04180	1.855e-72	249.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHEI@28216|Betaproteobacteria,4AC9Q@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_3235708_11	365046.Rta_04390	8.738e-29	124.0	2DSKK@1|root,33GI2@2|Bacteria,1NKCM@1224|Proteobacteria,2VY12@28216|Betaproteobacteria,4AG3P@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3235708_0	365046.Rta_04380	2.136e-227	717.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VJGK@28216|Betaproteobacteria,4AAFM@80864|Comamonadaceae	28216|Betaproteobacteria	L	Dead deah box helicase domain protein	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
ZZS3_k127_3235708_4	358220.C380_22120	2.724e-121	394.0	COG0745@1|root,COG0745@2|Bacteria,1QUN8@1224|Proteobacteria,2VMWS@28216|Betaproteobacteria,4AG6K@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_3235708_1	358220.C380_22125	1.155e-225	730.0	COG0642@1|root,COG0642@2|Bacteria,1R6VZ@1224|Proteobacteria,2VPSF@28216|Betaproteobacteria,4AGEA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS3_k127_3235708_9	1215114.BBIU01000031_gene3508	2.701e-55	203.0	COG3108@1|root,COG3108@2|Bacteria,1N3XU@1224|Proteobacteria,1S94S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
ZZS3_k127_3235708_7	983917.RGE_26800	7.664e-91	313.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KISZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,sCache_2
ZZS3_k127_3235708_3	296591.Bpro_3023	3.407e-128	416.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,4AD3D@80864|Comamonadaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_3235708_6	296591.Bpro_3022	6.456e-115	380.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,4A9VB@80864|Comamonadaceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_3235708_5	887062.HGR_12362	1.487e-118	391.0	COG3181@1|root,COG3181@2|Bacteria,1NU2D@1224|Proteobacteria,2VMNN@28216|Betaproteobacteria,4ABVE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3235708_10	983917.RGE_22220	1.344e-45	183.0	COG1011@1|root,COG1011@2|Bacteria,1Q69Z@1224|Proteobacteria,2VQKJ@28216|Betaproteobacteria,1KM50@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_3235708_2	477184.KYC_27483	5.644e-146	466.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,2VK0V@28216|Betaproteobacteria,3T6UH@506|Alcaligenaceae	28216|Betaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS3_k127_3259554_3	365046.Rta_34660	3.255e-65	229.0	COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,2VRNB@28216|Betaproteobacteria,4ADY4@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
ZZS3_k127_3259554_4	365046.Rta_34670	4.472e-56	199.0	COG1764@1|root,COG1764@2|Bacteria,1RD1A@1224|Proteobacteria,2VR4T@28216|Betaproteobacteria,4ADK9@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS3_k127_3259554_0	365046.Rta_34680	2.383e-165	525.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4ACGS@80864|Comamonadaceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS3_k127_3259554_2	365046.Rta_34770	6.952e-148	473.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VMWW@28216|Betaproteobacteria,4ABTA@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_3259554_1	365046.Rta_34780	9.718e-159	512.0	COG3181@1|root,COG3181@2|Bacteria,1P88K@1224|Proteobacteria,2VJJP@28216|Betaproteobacteria,4AJD9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3275593_6	296591.Bpro_4023	2.673e-138	442.0	COG1028@1|root,COG3320@1|root,COG1028@2|Bacteria,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,2VKRX@28216|Betaproteobacteria,4AB29@80864|Comamonadaceae	28216|Betaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
ZZS3_k127_3275593_10	358220.C380_03065	3.052e-47	187.0	COG3937@1|root,COG3937@2|Bacteria,1RIXG@1224|Proteobacteria,2VT1J@28216|Betaproteobacteria,4ADWD@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM poly granule associated family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
ZZS3_k127_3275593_5	614083.AWQR01000001_gene3064	2.156e-140	458.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,2VMTI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
ZZS3_k127_3275593_8	338969.Rfer_3529	1.386e-122	401.0	COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,2VIDN@28216|Betaproteobacteria,4AB9D@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
ZZS3_k127_3275593_7	365046.Rta_08650	4.536e-123	398.0	COG0457@1|root,COG0457@2|Bacteria,1R3PT@1224|Proteobacteria,2VN88@28216|Betaproteobacteria,4ACX0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3275593_12	358220.C380_04195	3.952e-38	148.0	COG5592@1|root,COG5592@2|Bacteria,1RGUY@1224|Proteobacteria,2VSXC@28216|Betaproteobacteria,4AFQA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_3275593_2	358220.C380_02490	6.12e-206	650.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VIJ1@28216|Betaproteobacteria,4ACWF@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
ZZS3_k127_3275593_13	614083.AWQR01000001_gene3060	5.298e-38	143.0	COG4281@1|root,COG4281@2|Bacteria,1MZPP@1224|Proteobacteria,2VUK0@28216|Betaproteobacteria,4AEX2@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyl-coA-binding protein, ACBP	acb	-	-	-	-	-	-	-	-	-	-	-	ACBP
ZZS3_k127_3275593_11	365046.Rta_08600	5.771e-39	149.0	2EGJT@1|root,33ABY@2|Bacteria,1NGI4@1224|Proteobacteria,2VX3Y@28216|Betaproteobacteria,4AFJ4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
ZZS3_k127_3275593_4	365046.Rta_08590	4.868e-154	509.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,4A9QN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
ZZS3_k127_3275593_0	365046.Rta_08580	0.0	1152.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,4AC5Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS3_k127_3275593_3	365046.Rta_08570	1.056e-176	561.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,4ABZ4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_3275593_1	358220.C380_02460	5.607e-207	656.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2VIJP@28216|Betaproteobacteria,4AADC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_3275593_9	296591.Bpro_2111	3.035e-112	368.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,4AADV@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase dimerisation domain protein	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_3302725_3	215803.DB30_3736	5.291e-17	85.0	COG0664@1|root,COG0664@2|Bacteria,1QX5I@1224|Proteobacteria,43BY8@68525|delta/epsilon subdivisions,2X794@28221|Deltaproteobacteria,2YW6W@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS3_k127_3302725_0	296591.Bpro_2990	3.63e-280	892.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,2WHFQ@28216|Betaproteobacteria,4AJWJ@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,dCache_1
ZZS3_k127_3302725_5	397945.Aave_2273	1.324e-12	77.0	2BX2B@1|root,33F6D@2|Bacteria,1NI1S@1224|Proteobacteria,2VY38@28216|Betaproteobacteria,4AG17@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3302725_4	365046.Rta_27530	4.167e-16	84.0	COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,2WHKW@28216|Betaproteobacteria,4AJZM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
ZZS3_k127_3302725_1	1219031.BBJR01000070_gene1099	2.765e-94	325.0	COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,2VMVT@28216|Betaproteobacteria,4ABJS@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Mg_trans_NIPA
ZZS3_k127_3302725_2	864051.BurJ1DRAFT_3873	5.18e-62	216.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KJJD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	dbpA	GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591,ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
ZZS3_k127_3314110_4	365046.Rta_18270	3.43e-111	362.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,4AA5M@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS3_k127_3314110_5	595537.Varpa_3758	2.06e-82	287.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,2VQ0D@28216|Betaproteobacteria,4ADFN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
ZZS3_k127_3314110_3	1454004.AW11_02940	3.643e-113	389.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,Response_reg,dCache_3
ZZS3_k127_3314110_0	595537.Varpa_2455	0.0	1073.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,4AD4V@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	korC	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
ZZS3_k127_3314110_1	595537.Varpa_2456	0.0	1073.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,4A9VY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
ZZS3_k127_3314110_2	595537.Varpa_2457	2.209e-182	606.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,4ACNH@80864|Comamonadaceae	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
ZZS3_k127_3369399_0	365046.Rta_30920	6e-323	995.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria,4AD9X@80864|Comamonadaceae	28216|Betaproteobacteria	L	DEAD H associated domain protein	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
ZZS3_k127_3369399_6	296591.Bpro_1612	3.152e-84	287.0	COG1402@1|root,COG1402@2|Bacteria,1R4JB@1224|Proteobacteria,2VQJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
ZZS3_k127_3369399_1	296591.Bpro_1613	6.381e-201	633.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VKXA@28216|Betaproteobacteria,4ACF0@80864|Comamonadaceae	2|Bacteria	S	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS3_k127_3369399_13	1128421.JAGA01000003_gene2913	7.958e-07	57.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON,PRC
ZZS3_k127_3369399_3	365046.Rta_30900	1.429e-162	529.0	COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,2VMRJ@28216|Betaproteobacteria,4AA4N@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
ZZS3_k127_3369399_9	365046.Rta_30890	5.825e-32	134.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUHT@28216|Betaproteobacteria,4AF5X@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
ZZS3_k127_3369399_10	365046.Rta_30880	3.089e-22	106.0	2E44P@1|root,32Z0S@2|Bacteria,1NCNK@1224|Proteobacteria,2VXFD@28216|Betaproteobacteria,4AFK1@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3369399_8	365046.Rta_30870	7.935e-38	146.0	2EENB@1|root,338G8@2|Bacteria,1NED1@1224|Proteobacteria,2VXJ4@28216|Betaproteobacteria,4AFIY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
ZZS3_k127_3369399_12	595537.Varpa_4777	9.546e-09	57.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2VXNN@28216|Betaproteobacteria,4AFXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
ZZS3_k127_3369399_2	365046.Rta_30850	4.611e-188	599.0	COG4585@1|root,COG5278@1|root,COG4585@2|Bacteria,COG5278@2|Bacteria,1MWPN@1224|Proteobacteria,2VJR2@28216|Betaproteobacteria,4ABHZ@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	vsrA	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	CHASE3,HATPase_c,HisKA_3
ZZS3_k127_3369399_4	365046.Rta_30840	6.519e-127	406.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VHQ0@28216|Betaproteobacteria,4ACM6@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_3369399_7	365046.Rta_30830	8.794e-56	198.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VRW4@28216|Betaproteobacteria,4AE7N@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_3369399_5	1265502.KB905932_gene1786	6.308e-119	387.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,4AA9H@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
ZZS3_k127_3419468_5	232721.Ajs_3013	6.471e-63	225.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,4ACZ4@80864|Comamonadaceae	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	epsE	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS3_k127_3419468_0	365046.Rta_31550	3.347e-190	597.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,4AAHK@80864|Comamonadaceae	28216|Betaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
ZZS3_k127_3419468_2	365046.Rta_31540	8.287e-133	445.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,4A9TJ@80864|Comamonadaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
ZZS3_k127_3419468_1	365046.Rta_31530	6.961e-161	531.0	COG3523@1|root,COG3523@2|Bacteria,1R54M@1224|Proteobacteria,2VMZG@28216|Betaproteobacteria,4AJ6P@80864|Comamonadaceae	28216|Betaproteobacteria	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
ZZS3_k127_3419468_7	1157708.KB907453_gene4256	0.0001627	48.0	COG3455@1|root,COG3455@2|Bacteria,1N723@1224|Proteobacteria,2VWJC@28216|Betaproteobacteria,4AIM5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Type VI secretion system protein DotU	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
ZZS3_k127_3419468_3	365046.Rta_31510	6.085e-126	414.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2VPCV@28216|Betaproteobacteria,4AEAZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_3419468_6	365046.Rta_31500	3.037e-26	119.0	COG2916@1|root,COG2916@2|Bacteria,1NB7Y@1224|Proteobacteria,2WAIE@28216|Betaproteobacteria,4AFKM@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM histone family protein nucleoid-structuring protein H-NS	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
ZZS3_k127_3419468_4	319225.Plut_1886	7.835e-76	264.0	COG0472@1|root,COG0472@2|Bacteria,1FF74@1090|Chlorobi	1090|Chlorobi	M	Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
ZZS3_k127_348929_1	614083.AWQR01000011_gene2385	3.7e-222	691.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH9Y@28216|Betaproteobacteria,4AC4V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_348929_5	365046.Rta_14610	5.555e-55	197.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2VU5M@28216|Betaproteobacteria,4AENB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
ZZS3_k127_348929_4	760117.JN27_05525	5.106e-55	194.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2VSQ1@28216|Betaproteobacteria,477AF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
ZZS3_k127_348929_3	1095769.CAHF01000022_gene199	1.179e-69	246.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VRJ0@28216|Betaproteobacteria,4772C@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
ZZS3_k127_348929_7	460265.Mnod_6117	6.938e-46	177.0	COG3324@1|root,COG3324@2|Bacteria,1N1P5@1224|Proteobacteria,2USX8@28211|Alphaproteobacteria	1224|Proteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_348929_8	1121127.JAFA01000047_gene51	2.221e-27	116.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2VVBQ@28216|Betaproteobacteria,1K857@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_348929_6	543728.Vapar_3360	7.997e-49	190.0	COG3832@1|root,COG3832@2|Bacteria,1RI3S@1224|Proteobacteria,2VVCX@28216|Betaproteobacteria,4AFCW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_348929_9	1276756.AUEX01000004_gene2395	6.852e-21	99.0	2DNIN@1|root,32XPX@2|Bacteria,1N56X@1224|Proteobacteria,2VU83@28216|Betaproteobacteria,4AF24@80864|Comamonadaceae	28216|Betaproteobacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
ZZS3_k127_348929_10	582744.Msip34_0959	2.768e-18	91.0	COG0484@1|root,COG0484@2|Bacteria,1N16C@1224|Proteobacteria,2VTZA@28216|Betaproteobacteria	28216|Betaproteobacteria	O	DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
ZZS3_k127_348929_0	1095769.CAHF01000015_gene2804	9.975e-245	757.0	COG4948@1|root,COG4948@2|Bacteria,1MVFW@1224|Proteobacteria,2VH6E@28216|Betaproteobacteria,4763P@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	mdlA1	-	4.2.1.81	ko:K22209	-	-	-	-	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_348929_2	296591.Bpro_3099	9.479e-98	328.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,2WG6V@28216|Betaproteobacteria,4AJUG@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_3530597_18	365046.Rta_32220	4.373e-103	337.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2VH5W@28216|Betaproteobacteria,4AAKP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Basic membrane lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
ZZS3_k127_3530597_20	365046.Rta_22900	3.098e-87	318.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,4AA5A@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
ZZS3_k127_3530597_8	543728.Vapar_3887	2.318e-180	585.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2VI56@28216|Betaproteobacteria,4AB7B@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
ZZS3_k127_3530597_13	1268622.AVS7_00615	5.709e-162	515.0	COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,2VNQF@28216|Betaproteobacteria,4AD2M@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS3_k127_3530597_5	365046.Rta_32340	7.867e-218	681.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2VH5W@28216|Betaproteobacteria,4ACEQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Basic membrane lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
ZZS3_k127_3530597_11	365046.Rta_32350	1.637e-169	536.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2VHBU@28216|Betaproteobacteria,4A9SA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ZZS3_k127_3530597_17	1437824.BN940_16971	7.396e-113	375.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2VH2R@28216|Betaproteobacteria,3T8UU@506|Alcaligenaceae	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ZZS3_k127_3530597_2	1123504.JQKD01000013_gene1053	5.417e-264	820.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2WGJY@28216|Betaproteobacteria,4AA9R@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
ZZS3_k127_3530597_14	1123504.JQKD01000013_gene1055	4.406e-158	503.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2VJ6D@28216|Betaproteobacteria,4ABK6@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_3530597_4	365046.Rta_32380	1.516e-222	698.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,4AAFW@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein domain protein	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
ZZS3_k127_3530597_1	535289.Dtpsy_2449	0.0	1193.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,4AB6W@80864|Comamonadaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS3_k127_3530597_9	1380390.JIAT01000013_gene123	8.458e-179	585.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
ZZS3_k127_3530597_25	1120949.KB903303_gene6687	3.582e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2IHGM@201174|Actinobacteria,4DD7T@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_3530597_6	1005048.CFU_0052	4.564e-213	694.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria,473EC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
ZZS3_k127_3530597_26	301.JNHE01000006_gene1076	2.323e-16	94.0	2B3X8@1|root,31WM6@2|Bacteria,1RFUV@1224|Proteobacteria,1RNAH@1236|Gammaproteobacteria,1YDAE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
ZZS3_k127_3530597_16	338969.Rfer_2533	1.727e-127	413.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,4AE55@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_3530597_19	1454004.AW11_01338	2.605e-101	336.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,1KQV4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
ZZS3_k127_3530597_23	395495.Lcho_0789	5.704e-60	229.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VQID@28216|Betaproteobacteria,1KM40@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
ZZS3_k127_3530597_7	365046.Rta_32420	6.32e-192	607.0	COG1073@1|root,COG1073@2|Bacteria,1NX52@1224|Proteobacteria,2VMJ0@28216|Betaproteobacteria,4ACGE@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3530597_24	365046.Rta_09260	9.996e-46	171.0	COG2944@1|root,COG2944@2|Bacteria,1N21E@1224|Proteobacteria,2VUAS@28216|Betaproteobacteria,4AF56@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
ZZS3_k127_3530597_15	365046.Rta_32430	8.753e-139	447.0	COG0583@1|root,COG0583@2|Bacteria,1PISE@1224|Proteobacteria,2VKB4@28216|Betaproteobacteria,4ACJE@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_3530597_0	365046.Rta_32440	0.0	1320.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
ZZS3_k127_3530597_3	365046.Rta_32450	3.408e-250	818.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2VMSN@28216|Betaproteobacteria,4ABYN@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
ZZS3_k127_3530597_12	365046.Rta_32460	4.806e-164	523.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VI0T@28216|Betaproteobacteria,4ABD1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3530597_22	365046.Rta_32470	8.629e-67	229.0	COG0824@1|root,COG0824@2|Bacteria,1RG6B@1224|Proteobacteria,2VTAU@28216|Betaproteobacteria,4ADWM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
ZZS3_k127_3530597_21	365046.Rta_02210	8.236e-68	250.0	COG1335@1|root,COG1335@2|Bacteria,1MZP9@1224|Proteobacteria,2VSME@28216|Betaproteobacteria,4AEYF@80864|Comamonadaceae	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
ZZS3_k127_3530597_10	365046.Rta_05870	8.701e-173	544.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP8D@28216|Betaproteobacteria,4AGBG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_356888_6	338969.Rfer_3271	2.095e-31	139.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
ZZS3_k127_356888_0	1157708.KB907464_gene457	1.498e-199	631.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2VHFA@28216|Betaproteobacteria,4AAC9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_356888_3	365046.Rta_34590	2.03e-93	315.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,2VKK9@28216|Betaproteobacteria,4AABS@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS3_k127_356888_2	365046.Rta_34580	1.166e-100	351.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,4AA5X@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS3_k127_356888_5	1198452.Jab_2c16890	2.177e-49	194.0	29DRS@1|root,300PM@2|Bacteria,1RF8B@1224|Proteobacteria,2VR3X@28216|Betaproteobacteria,475VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_356888_4	595537.Varpa_2961	5.728e-67	235.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria,2VVFK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
ZZS3_k127_356888_7	365046.Rta_34550	5.226e-26	113.0	2ANGV@1|root,31DFK@2|Bacteria,1RJ5C@1224|Proteobacteria,2VSDR@28216|Betaproteobacteria,4AECR@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	hctB	-	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	HC2
ZZS3_k127_356888_1	1276756.AUEX01000006_gene3137	1.074e-151	479.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,4AAQ5@80864|Comamonadaceae	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
ZZS3_k127_3574213_2	296591.Bpro_2391	4.044e-197	626.0	COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2VHVE@28216|Betaproteobacteria,4ACY4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
ZZS3_k127_3574213_5	365044.Pnap_2185	6.397e-91	306.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,2VQGW@28216|Betaproteobacteria,4AJWF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
ZZS3_k127_3574213_1	365046.Rta_20430	1.649e-272	843.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,4AACM@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
ZZS3_k127_3574213_4	365046.Rta_20420	3e-128	423.0	COG2199@1|root,COG2199@2|Bacteria,1NS2H@1224|Proteobacteria,2W069@28216|Betaproteobacteria,4AH3A@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ZZS3_k127_3574213_3	365046.Rta_20420	8.941e-130	426.0	COG2199@1|root,COG2199@2|Bacteria,1NS2H@1224|Proteobacteria,2W069@28216|Betaproteobacteria,4AH3A@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ZZS3_k127_3574213_0	365044.Pnap_2176	0.0	1440.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,4AA2Y@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
ZZS3_k127_3627149_17	232721.Ajs_0236	1.035e-25	106.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,4AAJ8@80864|Comamonadaceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
ZZS3_k127_3627149_14	296591.Bpro_0218	1.15e-51	190.0	28NWD@1|root,2ZBU8@2|Bacteria,1RGNH@1224|Proteobacteria,2VRUN@28216|Betaproteobacteria,4ADTZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
ZZS3_k127_3627149_10	596153.Alide_0371	1.374e-111	367.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,4AAMG@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
ZZS3_k127_3627149_7	1100721.ALKO01000008_gene2593	3.763e-139	447.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,4AAVK@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exodeoxyribonuclease III xth	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
ZZS3_k127_3627149_9	420662.Mpe_A3033	3.697e-132	427.0	COG3781@1|root,COG3781@2|Bacteria,1MX91@1224|Proteobacteria,2VHY9@28216|Betaproteobacteria,1KKHG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
ZZS3_k127_3627149_13	1287116.X734_13430	8.12e-58	211.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS3_k127_3627149_8	596154.Alide2_4271	3.573e-133	434.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,2VKGK@28216|Betaproteobacteria,4AC95@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM phospholipase A1	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
ZZS3_k127_3627149_16	365046.Rta_04080	9.188e-33	148.0	COG4314@1|root,COG4314@2|Bacteria,1N3VH@1224|Proteobacteria,2VVED@28216|Betaproteobacteria,4AEZ6@80864|Comamonadaceae	28216|Betaproteobacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3627149_0	365046.Rta_04090	0.0	1164.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,4AAKB@80864|Comamonadaceae	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS3_k127_3627149_4	365046.Rta_04140	6.953e-154	492.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2VIH3@28216|Betaproteobacteria,4A9PF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
ZZS3_k127_3627149_12	543728.Vapar_1223	2.123e-61	223.0	COG1266@1|root,COG1266@2|Bacteria,1RCJ4@1224|Proteobacteria,2VQUP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS3_k127_3627149_11	1121035.AUCH01000007_gene464	7.676e-82	293.0	COG4700@1|root,COG4700@2|Bacteria,1R577@1224|Proteobacteria,2VRNQ@28216|Betaproteobacteria,2KZ43@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria containing a divergent form of TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3627149_2	365046.Rta_25410	8.579e-202	637.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_3627149_1	338969.Rfer_3899	2.503e-293	910.0	COG0511@1|root,COG4799@1|root,COG0511@2|Bacteria,COG4799@2|Bacteria,1QZ71@1224|Proteobacteria	1224|Proteobacteria	EI	Biotin-requiring enzyme	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_lipoyl,CT_A_B,CT_C_D
ZZS3_k127_3627149_5	365046.Rta_04260	1.669e-149	486.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2VJES@28216|Betaproteobacteria,4ACZN@80864|Comamonadaceae	28216|Betaproteobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
ZZS3_k127_3627149_3	365046.Rta_04320	3.057e-161	516.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJU2@28216|Betaproteobacteria,4AB3J@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7	ko:K01476,ko:K01480,ko:K12255,ko:K18459	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157,R01990	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
ZZS3_k127_3627149_6	365046.Rta_21690	3.743e-145	466.0	COG3181@1|root,COG3181@2|Bacteria,1MVQR@1224|Proteobacteria,2VM4Q@28216|Betaproteobacteria,4AB71@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3639592_1	1157708.KB907451_gene4795	4.589e-91	317.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,4AC44@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM CHAD domain containing protein	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHAD,CYTH
ZZS3_k127_3639592_4	1122604.JONR01000006_gene2513	4.913e-38	149.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
ZZS3_k127_3639592_0	296591.Bpro_0079	9.829e-115	372.0	COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,2VNKQ@28216|Betaproteobacteria,4AFF2@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Glutathione S-transferase domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
ZZS3_k127_3639592_2	338969.Rfer_3374	5.953e-86	306.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K16966,ko:K17049,ko:K17052	ko00642,ko00920,ko01100,ko01120,ko01220,map00642,map00920,map01100,map01120,map01220	-	R05745,R09500	RC00275,RC02555	ko00000,ko00001,ko02000	5.A.3.8,5.A.3.9	-	-	EB_dh
ZZS3_k127_3639592_3	595537.Varpa_2796	3.684e-50	180.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS3_k127_3679164_4	365046.Rta_18315	3.644e-40	158.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,4ADHA@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
ZZS3_k127_3679164_1	365046.Rta_18320	3.276e-240	767.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2VIP8@28216|Betaproteobacteria,4A9MW@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM PHB de-polymerase domain protein	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
ZZS3_k127_3679164_3	358220.C380_11290	3.156e-117	407.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VQ8Z@28216|Betaproteobacteria,4ACR4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
ZZS3_k127_3679164_2	365046.Rta_18330	2.682e-210	661.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,4A9MF@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase, class I and II	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_3679164_0	365046.Rta_18340	1.316e-260	806.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,4AACI@80864|Comamonadaceae	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
ZZS3_k127_3688820_4	1415754.JQMK01000002_gene2228	5.187e-94	314.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,1RYP5@1236|Gammaproteobacteria,46B50@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
ZZS3_k127_3688820_3	1048339.KB913029_gene5016	3.432e-119	393.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,4EUV8@85013|Frankiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Methyltransf_31
ZZS3_k127_3688820_2	365046.Rta_17240	1.559e-120	393.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,4AA0F@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM Phosphoserine phosphatase SerB	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
ZZS3_k127_3688820_1	614083.AWQR01000010_gene1595	1.109e-140	470.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
ZZS3_k127_3688820_6	640081.Dsui_0513	4.492e-47	191.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,2VKM3@28216|Betaproteobacteria,2KY09@206389|Rhodocyclales	206389|Rhodocyclales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
ZZS3_k127_3688820_0	1007105.PT7_1206	2.195e-190	603.0	COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2VIIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_3688820_5	365046.Rta_17190	4.15e-91	307.0	COG0683@1|root,COG0683@2|Bacteria,1R9B2@1224|Proteobacteria,2VIJ4@28216|Betaproteobacteria,4ABGW@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular liganD-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_3792235_4	670292.JH26_05880	6.887e-64	224.0	297W1@1|root,2ZV2M@2|Bacteria,1QN4J@1224|Proteobacteria,2U80H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
ZZS3_k127_3792235_3	883078.HMPREF9695_03226	5.157e-130	423.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JTZB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	MA20_23605	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3792235_5	935863.AWZR01000005_gene2414	1.025e-63	240.0	COG3614@1|root,COG4251@1|root,COG3614@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,1XA5I@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_4
ZZS3_k127_3792235_1	365046.Rta_32560	1.202e-164	522.0	COG3181@1|root,COG3181@2|Bacteria,1N1ND@1224|Proteobacteria,2VKD0@28216|Betaproteobacteria,4ABBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3792235_2	365044.Pnap_3508	1.511e-154	494.0	COG3181@1|root,COG3181@2|Bacteria,1N1ND@1224|Proteobacteria,2VKD0@28216|Betaproteobacteria,4ACWZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3792235_0	365046.Rta_14260	1.246e-168	535.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VK33@28216|Betaproteobacteria,4ABQ4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Pyruvate carboxyltransferase	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
ZZS3_k127_3792235_6	365046.Rta_14270	6.228e-08	54.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,4AAPD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_379824_6	1265502.KB905929_gene2242	1.63e-128	420.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,4ABCJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
ZZS3_k127_379824_0	365046.Rta_13840	1.274e-318	993.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,4ABDQ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C
ZZS3_k127_379824_8	365046.Rta_13830	3.437e-110	360.0	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,4ABQU@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c	soxX	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
ZZS3_k127_379824_2	365046.Rta_13820	1.693e-148	473.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2VJ8Q@28216|Betaproteobacteria,4AC1N@80864|Comamonadaceae	28216|Betaproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
ZZS3_k127_379824_10	1268622.AVS7_01211	4.043e-54	191.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,4AEQV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulphur oxidation protein SoxZ	soxZ	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
ZZS3_k127_379824_9	1268622.AVS7_01212	9.1e-65	224.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria,4ADYP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
ZZS3_k127_379824_3	1100720.ALKN01000043_gene2735	1.314e-139	454.0	COG3258@1|root,COG4654@1|root,COG3258@2|Bacteria,COG4654@2|Bacteria,1QTYW@1224|Proteobacteria,2VIQV@28216|Betaproteobacteria,4ABQX@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_379824_1	688245.CtCNB1_2873	4.07e-253	786.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VI1T@28216|Betaproteobacteria,4A9V3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
ZZS3_k127_379824_13	399795.CtesDRAFT_PD1752	7.766e-30	134.0	COG0526@1|root,COG0526@2|Bacteria,1NBTN@1224|Proteobacteria,2VW6S@28216|Betaproteobacteria,4AF60@80864|Comamonadaceae	28216|Betaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
ZZS3_k127_379824_5	365046.Rta_13760	2.169e-133	437.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria,4AANI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_379824_12	365046.Rta_13750	3.553e-51	183.0	COG0640@1|root,COG0640@2|Bacteria,1Q9DY@1224|Proteobacteria,2VVWF@28216|Betaproteobacteria,4AF0M@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
ZZS3_k127_379824_11	312153.Pnuc_0808	1.29e-51	187.0	COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,2VTZ3@28216|Betaproteobacteria,1KAI9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
ZZS3_k127_379824_4	365046.Rta_13860	1.229e-136	451.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,4ABCJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
ZZS3_k127_379824_7	420662.Mpe_A0973	3.574e-120	413.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VIVP@28216|Betaproteobacteria,1KJPA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_3958201_3	365046.Rta_10350	1.019e-206	648.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria,4AAVV@80864|Comamonadaceae	28216|Betaproteobacteria	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
ZZS3_k127_3958201_31	1218076.BAYB01000053_gene6079	1.257e-36	141.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,1K7YI@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
ZZS3_k127_3958201_27	365044.Pnap_3871	2.477e-59	213.0	COG0745@1|root,COG0745@2|Bacteria,1NV31@1224|Proteobacteria,2VJ12@28216|Betaproteobacteria,4AAH5@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_3958201_4	1100720.ALKN01000040_gene2189	1.466e-197	627.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2VJCK@28216|Betaproteobacteria,4A9UI@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
ZZS3_k127_3958201_22	243160.BMA0271	7.754e-79	272.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1K3A8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_3958201_1	543728.Vapar_6289	2.971e-234	731.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2WHKM@28216|Betaproteobacteria,4AJZE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
ZZS3_k127_3958201_16	543728.Vapar_6290	1.773e-106	350.0	COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,2VJDD@28216|Betaproteobacteria,4ACUF@80864|Comamonadaceae	28216|Betaproteobacteria	P	Membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
ZZS3_k127_3958201_29	543728.Vapar_6291	1.401e-46	171.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_3958201_0	864051.BurJ1DRAFT_2762	8.286e-252	792.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,1KN43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_3958201_5	1123504.JQKD01000070_gene1735	6.191e-186	618.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VJWK@28216|Betaproteobacteria,4AAJ1@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
ZZS3_k127_3958201_10	398578.Daci_0792	2.159e-142	485.0	COG3181@1|root,COG3181@2|Bacteria,1NSWQ@1224|Proteobacteria,2VHX6@28216|Betaproteobacteria,4AC2C@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3958201_6	264198.Reut_B5398	3.78e-176	564.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,2VJHM@28216|Betaproteobacteria,1JZQQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
ZZS3_k127_3958201_32	1123504.JQKD01000041_gene2829	4.811e-35	152.0	2CIU6@1|root,32S8H@2|Bacteria,1MZTN@1224|Proteobacteria,2VT54@28216|Betaproteobacteria,4AEF5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3958201_38	296591.Bpro_4510	1.375e-12	79.0	COG2372@1|root,COG2372@2|Bacteria,1NZWY@1224|Proteobacteria,2W43X@28216|Betaproteobacteria	28216|Betaproteobacteria	M	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3958201_35	338969.Rfer_3686	2.319e-20	93.0	COG3212@1|root,COG3212@2|Bacteria,1P88W@1224|Proteobacteria,2W6CA@28216|Betaproteobacteria,4AIXX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
ZZS3_k127_3958201_15	296591.Bpro_1956	3.388e-116	377.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VIV6@28216|Betaproteobacteria,4ACAG@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07660,ko:K07667	ko01503,ko02020,ko02024,map01503,map02020,map02024	M00444,M00454,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_3958201_2	296591.Bpro_1957	2.911e-214	684.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2VIZI@28216|Betaproteobacteria,4AAQV@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	phoQ	-	2.7.13.3	ko:K07637	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c
ZZS3_k127_3958201_21	365046.Rta_27530	2.113e-89	322.0	COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,2WHKW@28216|Betaproteobacteria,4AJZM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
ZZS3_k127_3958201_30	365044.Pnap_4012	2.714e-39	147.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2VV9D@28216|Betaproteobacteria,4AG28@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
ZZS3_k127_3958201_28	296591.Bpro_1954	1.687e-56	202.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria,4AI5H@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
ZZS3_k127_3958201_36	1504672.669784561	8.139e-13	75.0	COG2372@1|root,COG2372@2|Bacteria,1NZWY@1224|Proteobacteria,2W43X@28216|Betaproteobacteria	28216|Betaproteobacteria	M	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3958201_11	1100720.ALKN01000045_gene461	9.229e-136	439.0	COG0491@1|root,COG0491@2|Bacteria,1MW35@1224|Proteobacteria,2VPNG@28216|Betaproteobacteria,4AH40@80864|Comamonadaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_3958201_8	296591.Bpro_1708	9.124e-159	506.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria,4AD6W@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3958201_9	1100720.ALKN01000040_gene2251	1.07e-156	500.0	COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2VPTY@28216|Betaproteobacteria,4AGS7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ZZS3_k127_3958201_12	1095769.CAHF01000011_gene2457	5.589e-135	438.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4731A@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3958201_33	1217718.ALOU01000013_gene301	4.643e-31	124.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,2VW2G@28216|Betaproteobacteria,1K9BT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
ZZS3_k127_3958201_25	1123504.JQKD01000003_gene645	1.796e-74	258.0	COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria,4AE1T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
ZZS3_k127_3958201_14	316056.RPC_3322	3.587e-118	402.0	2DBSD@1|root,2ZARI@2|Bacteria,1MX0F@1224|Proteobacteria,2TUNC@28211|Alphaproteobacteria,3JQX7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	MA20_42050	-	-	-	-	-	-	-	-	-	-	-	GRDB
ZZS3_k127_3958201_7	365046.Rta_05860	6.294e-163	517.0	COG3181@1|root,COG3181@2|Bacteria,1MYJX@1224|Proteobacteria,2VKS4@28216|Betaproteobacteria,4AA33@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_3958201_26	1268622.AVS7_03354	3.072e-62	242.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria,4AERQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
ZZS3_k127_3958201_37	365046.Rta_20680	1.266e-12	77.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
ZZS3_k127_3958201_23	1168059.KB899087_gene2888	2.063e-78	270.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,2U2DJ@28211|Alphaproteobacteria,3F04N@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	FCD	MA20_28005	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
ZZS3_k127_3958201_13	1510531.JQJJ01000009_gene1068	5.784e-135	437.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TUUJ@28211|Alphaproteobacteria,3JV1R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_3958201_20	318996.AXAZ01000030_gene4069	2.395e-97	322.0	COG0765@1|root,COG0765@2|Bacteria,1MX2Y@1224|Proteobacteria,2U1QD@28211|Alphaproteobacteria,3JXD0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
ZZS3_k127_3958201_19	1144310.PMI07_005386	5.582e-98	336.0	COG0765@1|root,COG0765@2|Bacteria,1MVB6@1224|Proteobacteria,2U1XV@28211|Alphaproteobacteria,4BCA7@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
ZZS3_k127_3958201_17	639283.Snov_1742	4.053e-102	350.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,3EYKJ@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	PFAM ABC transporter related	glnQ	-	3.6.3.21	ko:K02028,ko:K02029,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
ZZS3_k127_3958201_18	1168059.KB899087_gene2893	5.883e-102	352.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,2U0MI@28211|Alphaproteobacteria,3EZHH@335928|Xanthobacteraceae	28211|Alphaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
ZZS3_k127_3958201_24	639283.Snov_1740	1.924e-75	255.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria,3F15F@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
ZZS3_k127_3958201_41	1173026.Glo7428_0629	1.807e-05	54.0	COG0524@1|root,COG0524@2|Bacteria,1G2YU@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ZZS3_k127_3962853_6	365046.Rta_17440	5.163e-98	323.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,4AA10@80864|Comamonadaceae	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
ZZS3_k127_3962853_3	1268622.AVS7_04544	1.989e-128	425.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,4AATW@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
ZZS3_k127_3962853_5	365046.Rta_17420	3.334e-102	352.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VJN4@28216|Betaproteobacteria,4AAJT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_3962853_7	1458275.AZ34_07895	9.558e-67	230.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VJN4@28216|Betaproteobacteria,4AAJT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_3962853_1	365046.Rta_17410	5.942e-207	649.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2VH1D@28216|Betaproteobacteria,4ABMD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_3962853_2	365046.Rta_17400	1.056e-177	588.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,4ABC8@80864|Comamonadaceae	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
ZZS3_k127_3962853_4	365046.Rta_17390	1.807e-126	409.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2VHSZ@28216|Betaproteobacteria,4AANF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_3962853_0	365046.Rta_17380	2.431e-227	710.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,4AACP@80864|Comamonadaceae	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
ZZS3_k127_3965930_0	365046.Rta_33910	7.625e-240	745.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,4ABBZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
ZZS3_k127_3965930_2	365046.Rta_21560	2.956e-159	508.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VMFS@28216|Betaproteobacteria,4AES4@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS3_k127_3965930_5	1458275.AZ34_17025	6.749e-116	378.0	COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,2VJV9@28216|Betaproteobacteria,4AA5W@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	pcaR2	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
ZZS3_k127_3965930_3	358220.C380_19345	1.161e-127	412.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2VIR2@28216|Betaproteobacteria,4AAYG@80864|Comamonadaceae	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	pcaI	-	2.8.3.6	ko:K01031	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
ZZS3_k127_3965930_4	688245.CtCNB1_0684	7.185e-122	393.0	COG2057@1|root,COG2057@2|Bacteria,1MWW1@1224|Proteobacteria,2VIBE@28216|Betaproteobacteria,4ABU9@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Coenzyme A transferase	pcaJ	-	2.8.3.6	ko:K01032	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
ZZS3_k127_3965930_1	1331060.RLDS_11300	7.584e-186	584.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K04I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_397879_3	365046.Rta_34180	6.824e-103	336.0	COG0351@1|root,COG0351@2|Bacteria,1QUEP@1224|Proteobacteria,2WEGK@28216|Betaproteobacteria,4A9N5@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase type-1	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
ZZS3_k127_397879_1	1458275.AZ34_03590	1.12e-235	742.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,4AAY9@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_397879_0	365046.Rta_34240	4.294e-297	915.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,4AC6F@80864|Comamonadaceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
ZZS3_k127_397879_5	365046.Rta_34250	5.331e-36	153.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,4AEZK@80864|Comamonadaceae	28216|Betaproteobacteria	KL	Belongs to the transcriptional regulatory Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
ZZS3_k127_397879_2	365046.Rta_34260	8.116e-177	560.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,4AASV@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
ZZS3_k127_397879_4	595537.Varpa_5235	1.353e-81	274.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,4ADVX@80864|Comamonadaceae	28216|Betaproteobacteria	S	SNARE associated Golgi protein	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS3_k127_401158_4	365046.Rta_35630	9.235e-110	359.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,4AAK6@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM response regulator receiver	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
ZZS3_k127_401158_0	365046.Rta_35640	0.0	1069.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,4A9SK@80864|Comamonadaceae	28216|Betaproteobacteria	T	Signal transduction histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
ZZS3_k127_401158_6	614083.AWQR01000032_gene2900	1.233e-63	225.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,4AE7P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
ZZS3_k127_401158_3	365046.Rta_35660	5.814e-186	591.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,4ABU1@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
ZZS3_k127_401158_2	365046.Rta_13730	4.853e-224	700.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,4AA1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	soxF	-	1.8.2.1,1.8.5.4	ko:K05301,ko:K17218	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528,R10152	RC00168,RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
ZZS3_k127_401158_7	365046.Rta_13740	5.076e-28	119.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria,2VVR2@28216|Betaproteobacteria,4AFCM@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_401158_5	365046.Rta_35670	4.722e-64	225.0	COG1704@1|root,COG1704@2|Bacteria,1NB23@1224|Proteobacteria,2VWMF@28216|Betaproteobacteria,4AFDX@80864|Comamonadaceae	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS3_k127_401158_1	365046.Rta_35680	1.583e-227	707.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,4AA8U@80864|Comamonadaceae	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
ZZS3_k127_4017001_16	365046.Rta_35000	1.368e-73	249.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,4AC3Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4017001_6	358220.C380_02670	8.26e-155	496.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4017001_21	338969.Rfer_3535	7.609e-35	136.0	2E54A@1|root,32ZX9@2|Bacteria,1N8HJ@1224|Proteobacteria,2VVW9@28216|Betaproteobacteria,4AFMV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
ZZS3_k127_4017001_2	365046.Rta_35030	5.088e-210	659.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,4AA3P@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	mmaA3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
ZZS3_k127_4017001_15	296591.Bpro_0592	1.723e-74	258.0	COG1846@1|root,COG1846@2|Bacteria,1MZE9@1224|Proteobacteria,2VT2T@28216|Betaproteobacteria,4ADVS@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	badR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_4017001_0	365046.Rta_35050	6.309e-294	917.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,4AACS@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_4017001_5	375286.mma_3324	1.798e-156	512.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,4748D@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	tcaB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
ZZS3_k127_4017001_20	448385.sce1138	2.297e-39	154.0	COG1670@1|root,COG1670@2|Bacteria,1N4JG@1224|Proteobacteria,43DM6@68525|delta/epsilon subdivisions,2X65M@28221|Deltaproteobacteria,2Z393@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS3_k127_4017001_18	1144342.PMI40_00831	1.904e-57	204.0	2DM8S@1|root,32731@2|Bacteria,1RJ1D@1224|Proteobacteria,2VSVS@28216|Betaproteobacteria,474J7@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4017001_3	358220.C380_20000	1.892e-171	547.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VM1X@28216|Betaproteobacteria,4A9SE@80864|Comamonadaceae	28216|Betaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
ZZS3_k127_4017001_8	365046.Rta_35070	3.057e-152	486.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,2VJKN@28216|Betaproteobacteria,4AAV8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 5-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
ZZS3_k127_4017001_10	365046.Rta_35080	6.94e-128	421.0	COG0697@1|root,COG0697@2|Bacteria,1MX07@1224|Proteobacteria,2VN9W@28216|Betaproteobacteria,4ACVN@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_4017001_14	365046.Rta_35090	1.232e-96	322.0	COG0108@1|root,COG0108@2|Bacteria,1RAK1@1224|Proteobacteria,2WGAH@28216|Betaproteobacteria,4AG7W@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
ZZS3_k127_4017001_4	365046.Rta_23880	1.128e-167	531.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,4A9RA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_4017001_17	365046.Rta_03040	2.164e-60	224.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2VX3A@28216|Betaproteobacteria,4AJB3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS3_k127_4017001_19	595537.Varpa_0307	3.47e-53	203.0	COG3218@1|root,COG3218@2|Bacteria,1N8NT@1224|Proteobacteria,2VTC7@28216|Betaproteobacteria,4AEC3@80864|Comamonadaceae	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
ZZS3_k127_4017001_12	365046.Rta_03020	1.134e-110	366.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,4AAHD@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS3_k127_4017001_11	365046.Rta_03010	3.618e-125	424.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,4AAMK@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM ABC transporter related	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS3_k127_4017001_7	365046.Rta_03000	1.602e-152	497.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,4AD03@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Permease MlaE	mlaE_2	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS3_k127_4017001_1	977880.RALTA_B0801	6.017e-266	837.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,2VJHM@28216|Betaproteobacteria,1K46N@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
ZZS3_k127_4017001_9	365046.Rta_02990	5.76e-136	442.0	COG0583@1|root,COG0583@2|Bacteria,1R5GV@1224|Proteobacteria,2VHEG@28216|Betaproteobacteria,4AAZW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_4017001_13	365046.Rta_02980	9.407e-109	354.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2VI0N@28216|Betaproteobacteria,4A9T8@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_4017827_2	365046.Rta_20980	1.774e-150	478.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,4AAJ4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase, class I and II	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_4017827_3	365046.Rta_20990	2.384e-144	463.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,4AC8B@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
ZZS3_k127_4017827_1	365046.Rta_21000	1.519e-201	632.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,4AAT0@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	pilT2	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS3_k127_4017827_0	365046.Rta_21010	3.112e-211	660.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,4AB8Q@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_4020693_2	365046.Rta_18790	1.748e-222	693.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,4AA22@80864|Comamonadaceae	28216|Betaproteobacteria	C	dehydrogenase, E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
ZZS3_k127_4020693_4	1366050.N234_13480	2.365e-196	619.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1K1V0@119060|Burkholderiaceae	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_4020693_1	987059.RBXJA2T_08013	5.636e-259	803.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1KJ4Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase	odhL	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_4020693_3	365044.Pnap_1859	1.74e-202	634.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,4AAAE@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM AFG1-family ATPase	yhcM	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
ZZS3_k127_4020693_10	1123504.JQKD01000031_gene4547	7.852e-13	81.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
ZZS3_k127_4020693_6	365046.Rta_18840	1.893e-140	449.0	COG0631@1|root,COG0631@2|Bacteria,1N72S@1224|Proteobacteria,2VK9S@28216|Betaproteobacteria,4AB7X@80864|Comamonadaceae	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS3_k127_4020693_9	365046.Rta_18850	1.13e-26	111.0	COG5481@1|root,COG5481@2|Bacteria,1NAQ6@1224|Proteobacteria,2VW3I@28216|Betaproteobacteria,4AFHS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
ZZS3_k127_4020693_0	365046.Rta_18860	2.098e-314	980.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,4AAZJ@80864|Comamonadaceae	28216|Betaproteobacteria	KL	Helicase c2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
ZZS3_k127_4020693_7	596154.Alide2_3019	1.483e-118	409.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,4A9U0@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
ZZS3_k127_4020693_5	365046.Rta_18870	6.67e-146	469.0	COG0564@1|root,COG2302@1|root,COG0564@2|Bacteria,COG2302@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,4AB2B@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS3_k127_4020693_8	543728.Vapar_2181	1.64e-91	316.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,4ABE8@80864|Comamonadaceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
ZZS3_k127_4026947_1	94624.Bpet2412	5.09e-201	633.0	COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2VN4U@28216|Betaproteobacteria,3T5N2@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_4026947_2	667632.KB890187_gene3118	1.263e-185	585.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,1K3NA@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	namA	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
ZZS3_k127_4026947_3	196490.AUEZ01000008_gene5430	1.328e-96	325.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2TT0C@28211|Alphaproteobacteria,3JZP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	intracellular protease amidase	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
ZZS3_k127_4026947_0	1031711.RSPO_c02218	1.08e-207	659.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,1K13H@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	ydhP	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
ZZS3_k127_4027523_11	1100720.ALKN01000007_gene3052	1.194e-08	66.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYY@28216|Betaproteobacteria,4A9U4@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM carboxyl transferase	-	-	6.4.1.5	ko:K13778	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
ZZS3_k127_4027523_2	1157708.KB907455_gene3229	7.188e-141	463.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2VK16@28216|Betaproteobacteria,4ACKC@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
ZZS3_k127_4027523_4	296591.Bpro_3920	2.504e-84	284.0	COG1309@1|root,COG1309@2|Bacteria,1RGJ3@1224|Proteobacteria,2VHGC@28216|Betaproteobacteria,4ADI0@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
ZZS3_k127_4027523_3	338969.Rfer_2284	1.055e-91	311.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,4AATS@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
ZZS3_k127_4027523_7	296591.Bpro_2081	3.129e-55	199.0	2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,2VSNA@28216|Betaproteobacteria,4AEGZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
ZZS3_k127_4027523_0	887062.HGR_08589	8.274e-207	652.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,4AAJ6@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_4027523_6	365046.Rta_09230	3.347e-62	224.0	COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,2VSCM@28216|Betaproteobacteria,4AEM3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_4027523_10	404589.Anae109_0604	2.313e-39	154.0	COG3832@1|root,COG3832@2|Bacteria,1MZ7K@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_4027523_5	1458275.AZ34_16850	1.067e-63	228.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VSH3@28216|Betaproteobacteria,4AEBC@80864|Comamonadaceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_4027523_8	296591.Bpro_3925	6.726e-44	162.0	COG3795@1|root,COG3795@2|Bacteria,1RJ0K@1224|Proteobacteria,2VSJT@28216|Betaproteobacteria,4AJEM@80864|Comamonadaceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_4027523_1	296591.Bpro_3931	3.309e-146	467.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2VM6G@28216|Betaproteobacteria,4AGM8@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
ZZS3_k127_4027523_9	365046.Rta_09190	1.321e-43	160.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2VJC1@28216|Betaproteobacteria,4AA2P@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_4050818_7	1123504.JQKD01000013_gene1061	2.917e-122	392.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,4AC2J@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	abmC	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_4050818_3	365046.Rta_18160	6.728e-196	617.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,4AC8Z@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	abmD	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4050818_9	365046.Rta_18170	9.086e-49	193.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,4AE78@80864|Comamonadaceae	28216|Betaproteobacteria	J	endoribonuclease L-PSP	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS3_k127_4050818_1	365046.Rta_18180	4.525e-238	739.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2VHDV@28216|Betaproteobacteria,4AA6Z@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4050818_8	365046.Rta_18220	2.042e-99	344.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2VN1E@28216|Betaproteobacteria,4A9U9@80864|Comamonadaceae	28216|Betaproteobacteria	K	regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_4050818_5	1156919.QWC_08341	3.069e-148	475.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VPZ2@28216|Betaproteobacteria,3T586@506|Alcaligenaceae	28216|Betaproteobacteria	E	COG0119 Isopropylmalate homocitrate citramalate synthases	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
ZZS3_k127_4050818_6	762376.AXYL_01255	7.874e-138	445.0	COG3181@1|root,COG3181@2|Bacteria,1R8ZB@1224|Proteobacteria,2VHN1@28216|Betaproteobacteria,3T725@506|Alcaligenaceae	28216|Betaproteobacteria	S	Extra-cytoplasmic solute receptor family protein 24	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4050818_2	762376.AXYL_01254	7.497e-208	653.0	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2VK1H@28216|Betaproteobacteria,3T5M3@506|Alcaligenaceae	28216|Betaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_4050818_4	1123367.C666_11990	4.179e-158	512.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2VJ94@28216|Betaproteobacteria,2KYCV@206389|Rhodocyclales	206389|Rhodocyclales	K	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2083,Peptidase_M78
ZZS3_k127_4050818_0	365046.Rta_18230	1.387e-282	873.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,4AA6N@80864|Comamonadaceae	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase large subunit	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
ZZS3_k127_4069843_3	1123504.JQKD01000011_gene2421	9.708e-149	488.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VM0U@28216|Betaproteobacteria,4AB0P@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4069843_0	1123504.JQKD01000011_gene2420	1.603e-212	670.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHSX@28216|Betaproteobacteria,4AB2T@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4069843_4	1123504.JQKD01000011_gene2419	2.443e-130	421.0	COG1414@1|root,COG1414@2|Bacteria,1MXNI@1224|Proteobacteria,2VIHW@28216|Betaproteobacteria,4AGD7@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_4069843_1	748247.AZKH_1911	3.549e-208	671.0	COG0520@1|root,COG0520@2|Bacteria,1NIKU@1224|Proteobacteria,2VZY7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS3_k127_4069843_8	795666.MW7_0585	2.67e-83	287.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4069843_5	543728.Vapar_5799	5.708e-115	396.0	COG0583@1|root,COG0583@2|Bacteria,1RFW8@1224|Proteobacteria,2VSC8@28216|Betaproteobacteria,4AHD4@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_4069843_9	1005048.CFU_3147	2.74e-59	217.0	COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,2VQPW@28216|Betaproteobacteria,4746X@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_4069843_10	1144325.PMI22_03353	1.063e-54	202.0	COG0583@1|root,COG0583@2|Bacteria,1N3XX@1224|Proteobacteria,1RR3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_4069843_7	1157708.KB907468_gene127	3.843e-101	336.0	COG0778@1|root,COG0778@2|Bacteria,1RD6V@1224|Proteobacteria,2VS6J@28216|Betaproteobacteria,4AGYT@80864|Comamonadaceae	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
ZZS3_k127_4069843_6	1123504.JQKD01000048_gene1401	8.607e-103	336.0	294JI@1|root,2ZBVI@2|Bacteria,1RBH0@1224|Proteobacteria,2VQUD@28216|Betaproteobacteria,4AG9K@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4863
ZZS3_k127_4069843_2	1123504.JQKD01000048_gene1400	3.455e-151	482.0	COG3181@1|root,COG3181@2|Bacteria,1RBU2@1224|Proteobacteria,2VQGA@28216|Betaproteobacteria,4AG9T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4080590_10	365046.Rta_06600	8.824e-110	359.0	COG2207@1|root,COG2207@2|Bacteria,1R4MG@1224|Proteobacteria,2VISE@28216|Betaproteobacteria,4ABDZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
ZZS3_k127_4080590_36	1265502.KB905946_gene1128	5.352e-12	77.0	28WGJ@1|root,2ZIGP@2|Bacteria,1P9DI@1224|Proteobacteria,2W5VH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_27	748247.AZKH_2441	7.425e-43	164.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2W3J8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS3_k127_4080590_7	543728.Vapar_1653	3.382e-126	409.0	COG2129@1|root,COG2129@2|Bacteria,1MVNK@1224|Proteobacteria,2VPDN@28216|Betaproteobacteria,4AHDU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS3_k127_4080590_4	365046.Rta_07150	2.37e-143	459.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2VKPI@28216|Betaproteobacteria,4AGQT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
ZZS3_k127_4080590_19	365046.Rta_36320	6.31e-63	219.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,2VSG8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
ZZS3_k127_4080590_2	1100720.ALKN01000052_gene507	2.058e-152	494.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_4080590_35	1504672.669785590	1.419e-24	109.0	COG4191@1|root,COG5455@1|root,COG4191@2|Bacteria,COG5455@2|Bacteria,1RJ9A@1224|Proteobacteria,2VRVC@28216|Betaproteobacteria,4AF8K@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
ZZS3_k127_4080590_11	595537.Varpa_1815	7.723e-105	346.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2VN75@28216|Betaproteobacteria,4AH58@80864|Comamonadaceae	28216|Betaproteobacteria	E	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
ZZS3_k127_4080590_13	595537.Varpa_1816	4.179e-85	298.0	28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2VTKQ@28216|Betaproteobacteria,4AHVD@80864|Comamonadaceae	28216|Betaproteobacteria	E	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
ZZS3_k127_4080590_26	595537.Varpa_1817	2.05e-45	177.0	2E3CR@1|root,32YC0@2|Bacteria,1N9Q9@1224|Proteobacteria,2VVMK@28216|Betaproteobacteria,4AIFJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nitrile hydratase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293,NHase_beta
ZZS3_k127_4080590_37	1095769.CAHF01000005_gene1592	2.623e-07	60.0	2F7BR@1|root,33ZSW@2|Bacteria,1NXMV@1224|Proteobacteria,2W3VJ@28216|Betaproteobacteria,4784G@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_20	1096930.L284_20945	2.1e-61	224.0	2D94Q@1|root,33E80@2|Bacteria,1R37G@1224|Proteobacteria,2TZZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
ZZS3_k127_4080590_33	365046.Rta_06060	8.302e-27	113.0	2E77M@1|root,331RD@2|Bacteria,1N9TP@1224|Proteobacteria,2VVPH@28216|Betaproteobacteria,4AFBD@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_25	13689.BV96_02354	8.588e-47	177.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_40	365046.Rta_12900	1.466e-05	55.0	2EIPZ@1|root,33CFF@2|Bacteria,1NJHP@1224|Proteobacteria,2VY0Z@28216|Betaproteobacteria,4AFWK@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_31	296591.Bpro_4510	6.787e-30	131.0	COG2372@1|root,COG2372@2|Bacteria,1NZWY@1224|Proteobacteria,2W43X@28216|Betaproteobacteria	28216|Betaproteobacteria	M	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_16	1235457.C404_02835	8.039e-75	269.0	COG1680@1|root,COG1680@2|Bacteria,1RIYG@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440
ZZS3_k127_4080590_0	365046.Rta_29230	4.478e-186	588.0	COG2223@1|root,COG2223@2|Bacteria,1QWEE@1224|Proteobacteria	1224|Proteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS3_k127_4080590_8	365046.Rta_10520	1.426e-124	406.0	COG0697@1|root,COG0697@2|Bacteria,1R3W3@1224|Proteobacteria,2VND3@28216|Betaproteobacteria,4ACJJ@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_4080590_5	936455.KI421499_gene3109	1.233e-142	459.0	COG0584@1|root,COG0584@2|Bacteria,1MWIS@1224|Proteobacteria,2TTCW@28211|Alphaproteobacteria,3JT0W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS3_k127_4080590_24	1144319.PMI16_01415	5.952e-50	180.0	COG3631@1|root,COG3631@2|Bacteria,1RDDF@1224|Proteobacteria,2VV5D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
ZZS3_k127_4080590_18	420662.Mpe_A3300	7.47e-66	233.0	COG0840@1|root,COG0840@2|Bacteria,1RG1E@1224|Proteobacteria,2VRUW@28216|Betaproteobacteria,1KMAV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilJ
ZZS3_k127_4080590_29	1537715.JQFJ01000002_gene1831	1.099e-39	154.0	COG4270@1|root,COG4270@2|Bacteria,1N2NG@1224|Proteobacteria	1224|Proteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_22	296591.Bpro_2066	3.143e-58	205.0	COG3609@1|root,COG3609@2|Bacteria,1RHNZ@1224|Proteobacteria,2VSYD@28216|Betaproteobacteria,4AEMF@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4080590_6	296591.Bpro_2065	3.134e-131	427.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,2VKEH@28216|Betaproteobacteria,4ACC3@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
ZZS3_k127_4080590_1	365046.Rta_28350	6.734e-181	588.0	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,2VHDP@28216|Betaproteobacteria,4A9ST@80864|Comamonadaceae	28216|Betaproteobacteria	O	MreB/Mbl protein	yegD	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
ZZS3_k127_4080590_14	1410619.SRDD_00360	6.411e-81	271.0	COG3791@1|root,COG3791@2|Bacteria,1REMP@1224|Proteobacteria,1S3AW@1236|Gammaproteobacteria,4049V@613|Serratia	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
ZZS3_k127_4080590_12	1123073.KB899243_gene618	1.059e-85	286.0	COG3832@1|root,COG3832@2|Bacteria,1RDXJ@1224|Proteobacteria,1SN77@1236|Gammaproteobacteria,1X7VE@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_4080590_21	1123073.KB899243_gene617	2.673e-58	203.0	COG0640@1|root,COG0640@2|Bacteria,1RIJ9@1224|Proteobacteria,1SNVH@1236|Gammaproteobacteria,1X7QM@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_4080590_15	1532557.JL37_18845	5.849e-75	255.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VRD1@28216|Betaproteobacteria,3T7K6@506|Alcaligenaceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_4080590_28	338969.Rfer_2454	3.256e-42	171.0	2AFSS@1|root,315UT@2|Bacteria,1PW9S@1224|Proteobacteria,2WBUU@28216|Betaproteobacteria,4AICS@80864|Comamonadaceae	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
ZZS3_k127_4080590_9	543728.Vapar_0122	1.706e-115	394.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2VK7I@28216|Betaproteobacteria,4ACD1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
ZZS3_k127_4080590_30	1157708.KB907453_gene4395	1.096e-34	136.0	COG5460@1|root,COG5460@2|Bacteria,1PTUZ@1224|Proteobacteria,2VV0Z@28216|Betaproteobacteria,4AF9I@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
ZZS3_k127_4080590_17	1157708.KB907457_gene2572	5.92e-66	233.0	COG0664@1|root,COG0664@2|Bacteria,1RK3F@1224|Proteobacteria,2VT59@28216|Betaproteobacteria,4AFUR@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_4080590_3	543728.Vapar_4418	6.031e-149	490.0	COG0633@1|root,COG2114@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,1N5XC@1224|Proteobacteria,2VP3A@28216|Betaproteobacteria,4ABN2@80864|Comamonadaceae	28216|Betaproteobacteria	CT	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Guanylate_cyc
ZZS3_k127_4080590_32	1218352.B597_010105	8.381e-28	113.0	COG4944@1|root,COG4944@2|Bacteria,1MXEV@1224|Proteobacteria,1S7DP@1236|Gammaproteobacteria,1Z08U@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
ZZS3_k127_4082165_4	1123504.JQKD01000016_gene1949	5.6e-42	173.0	COG3181@1|root,COG3181@2|Bacteria,1NF9R@1224|Proteobacteria,2VM37@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4082165_2	1006000.GKAS_02866	7.014e-54	200.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_4082165_5	1095769.CAHF01000006_gene1827	1.706e-36	142.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,477HU@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS3_k127_4082165_6	296591.Bpro_3409	3.079e-27	121.0	COG2885@1|root,COG2885@2|Bacteria,1NMYI@1224|Proteobacteria,2VY3H@28216|Betaproteobacteria,4AG2A@80864|Comamonadaceae	28216|Betaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4082165_1	1157708.KB907453_gene4411	4.989e-147	472.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2VMR5@28216|Betaproteobacteria,4ABTE@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_4082165_7	365046.Rta_27570	1.057e-17	91.0	COG5455@1|root,COG5455@2|Bacteria,1NGVG@1224|Proteobacteria,2VVTN@28216|Betaproteobacteria,4AFGZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nickel/cobalt transporter regulator	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
ZZS3_k127_4082165_3	365046.Rta_27550	3.451e-44	162.0	2CC2Z@1|root,32WTM@2|Bacteria,1N4FS@1224|Proteobacteria,2VUUG@28216|Betaproteobacteria,4AIFT@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4082165_0	365046.Rta_27160	5.346e-236	738.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4AAPC@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
ZZS3_k127_4082165_8	358220.C380_16750	3.669e-08	55.0	2DSFF@1|root,33FYB@2|Bacteria,1NHKC@1224|Proteobacteria,2VY54@28216|Betaproteobacteria,4AFUZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4088750_8	365046.Rta_09740	3.268e-56	198.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,4A9UG@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
ZZS3_k127_4088750_7	365046.Rta_09730	3.422e-104	355.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,4A9Y5@80864|Comamonadaceae	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
ZZS3_k127_4088750_4	365046.Rta_09720	2.038e-179	565.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,4AANC@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
ZZS3_k127_4088750_0	365046.Rta_09710	5.366e-243	776.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,4AA6E@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_4088750_5	614083.AWQR01000021_gene217	8.003e-171	545.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,4AB8T@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
ZZS3_k127_4088750_3	365046.Rta_09690	4.832e-194	632.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,4ABEI@80864|Comamonadaceae	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
ZZS3_k127_4088750_1	365046.Rta_09680	4.941e-236	758.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,4AAXV@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
ZZS3_k127_4088750_2	1100721.ALKO01000020_gene940	2.465e-216	682.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,4ABVH@80864|Comamonadaceae	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
ZZS3_k127_4088750_6	1223521.BBJX01000001_gene842	1.491e-145	469.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,4ABB4@80864|Comamonadaceae	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_4089957_23	365046.Rta_17140	1.588e-37	155.0	COG2885@1|root,COG2885@2|Bacteria,1NMYI@1224|Proteobacteria,2VY3H@28216|Betaproteobacteria,4AG2A@80864|Comamonadaceae	28216|Betaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4089957_14	296591.Bpro_2735	1.19e-68	239.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,4ADC0@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
ZZS3_k127_4089957_17	358220.C380_15290	4.903e-57	203.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2VT1R@28216|Betaproteobacteria,4AED2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
ZZS3_k127_4089957_19	365044.Pnap_2088	1.359e-55	199.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VSW6@28216|Betaproteobacteria,4AEJJ@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_4089957_2	365046.Rta_05940	1.314e-195	626.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,2VIXB@28216|Betaproteobacteria,4ACAS@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
ZZS3_k127_4089957_21	935567.JAES01000019_gene1024	4.429e-48	188.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
ZZS3_k127_4089957_10	365044.Pnap_3583	1.407e-86	299.0	COG1376@1|root,COG1376@2|Bacteria,1MVI4@1224|Proteobacteria,2WAYN@28216|Betaproteobacteria,4AGA3@80864|Comamonadaceae	28216|Betaproteobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
ZZS3_k127_4089957_15	760117.JN27_22300	3.949e-65	239.0	COG3915@1|root,COG3915@2|Bacteria,1RDJN@1224|Proteobacteria,2VRG6@28216|Betaproteobacteria,474A4@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
ZZS3_k127_4089957_8	358220.C380_19305	2.992e-91	329.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,2VIBI@28216|Betaproteobacteria,4AE08@80864|Comamonadaceae	28216|Betaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ZZS3_k127_4089957_6	365046.Rta_17120	5.272e-119	387.0	COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VRTF@28216|Betaproteobacteria,4AE62@80864|Comamonadaceae	28216|Betaproteobacteria	Q	2-Keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_4089957_13	1033802.SSPSH_000945	2.768e-75	267.0	COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,1RXZH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_4089957_9	365046.Rta_17050	1.089e-87	299.0	COG0625@1|root,COG0625@2|Bacteria,1RAP2@1224|Proteobacteria,2VQGV@28216|Betaproteobacteria,4AD2P@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
ZZS3_k127_4089957_5	365046.Rta_18190	1.806e-147	475.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4089957_0	365046.Rta_12340	0.0	1553.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1-like protein	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
ZZS3_k127_4089957_11	365046.Rta_12330	2.108e-83	300.0	COG4726@1|root,COG4726@2|Bacteria,1NMBD@1224|Proteobacteria,2VYSP@28216|Betaproteobacteria,4AG2E@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4089957_3	365046.Rta_12320	1.251e-186	599.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
ZZS3_k127_4089957_18	365046.Rta_12310	2.75e-56	210.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria,4AFXW@80864|Comamonadaceae	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
ZZS3_k127_4089957_16	365046.Rta_12300	1.528e-57	213.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02456,ko:K08084	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl
ZZS3_k127_4089957_24	596154.Alide2_4407	2.911e-24	115.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,4AF9Z@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
ZZS3_k127_4089957_12	358220.C380_15330	6.49e-79	272.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,2VQQC@28216|Betaproteobacteria,4AAYH@80864|Comamonadaceae	28216|Betaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
ZZS3_k127_4089957_1	296591.Bpro_2084	1.887e-313	972.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2WGHH@28216|Betaproteobacteria,4AJWD@80864|Comamonadaceae	28216|Betaproteobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
ZZS3_k127_4089957_22	1276756.AUEX01000008_gene3165	3.909e-46	171.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,2VU7V@28216|Betaproteobacteria,4AF25@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM translation initiation factor SUI1	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
ZZS3_k127_4089957_20	365046.Rta_27350	7.312e-49	191.0	COG5470@1|root,COG5470@2|Bacteria,1RIH6@1224|Proteobacteria,2VSR7@28216|Betaproteobacteria,4AEKA@80864|Comamonadaceae	28216|Betaproteobacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
ZZS3_k127_4089957_7	365046.Rta_27370	1.457e-102	353.0	COG0640@1|root,COG0640@2|Bacteria,1MWCW@1224|Proteobacteria,2VRQN@28216|Betaproteobacteria,4AEYK@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_4089957_4	296591.Bpro_3011	5.019e-154	489.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VN5P@28216|Betaproteobacteria,4AGSI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4097905_2	595537.Varpa_0002	2.46e-197	617.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,4AAUR@80864|Comamonadaceae	28216|Betaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
ZZS3_k127_4097905_1	614083.AWQR01000003_gene2935	1.727e-253	787.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,4AAHN@80864|Comamonadaceae	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
ZZS3_k127_4097905_5	1268622.AVS7_00976	8.266e-19	86.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria,4AFCB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
ZZS3_k127_4097905_3	365046.Rta_38230	7.284e-45	167.0	COG0594@1|root,COG0594@2|Bacteria,1RI80@1224|Proteobacteria,2VSD0@28216|Betaproteobacteria,4AEFM@80864|Comamonadaceae	28216|Betaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
ZZS3_k127_4097905_4	398578.Daci_6057	3.935e-38	144.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,4AEUX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
ZZS3_k127_4097905_0	365046.Rta_38210	2.212e-262	818.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,4AA59@80864|Comamonadaceae	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
ZZS3_k127_410769_4	1123504.JQKD01000026_gene4270	1.066e-125	409.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,4A9ZJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
ZZS3_k127_410769_0	365046.Rta_08380	6.767e-178	574.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,4AA2V@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_410769_3	365046.Rta_08360	9.093e-132	426.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,4A9MH@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
ZZS3_k127_410769_7	365046.Rta_08350	1.253e-64	225.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,4AE0H@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS3_k127_410769_11	365046.Rta_08340	7.997e-30	121.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,4AEWK@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS3_k127_410769_8	365046.Rta_08330	4.148e-60	209.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,4AE73@80864|Comamonadaceae	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
ZZS3_k127_410769_10	365046.Rta_08320	1.115e-45	168.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_410769_9	614083.AWQR01000017_gene2273	9.684e-57	199.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,4ADZJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
ZZS3_k127_410769_6	1268622.AVS7_02903	5.22e-73	251.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,4ADX6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
ZZS3_k127_410769_2	614083.AWQR01000017_gene2271	1.25e-149	476.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,4AA0X@80864|Comamonadaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS3_k127_410769_1	1100720.ALKN01000030_gene1081	7.74e-150	475.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,4ABUC@80864|Comamonadaceae	28216|Betaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS3_k127_410769_5	543728.Vapar_1169	1.146e-114	375.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,4AA2J@80864|Comamonadaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS3_k127_4135764_6	365046.Rta_32070	1.706e-68	264.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,4ABP4@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS3_k127_4135764_4	365046.Rta_32060	4.304e-106	353.0	COG4255@1|root,COG4255@2|Bacteria,1R59K@1224|Proteobacteria,2VKW9@28216|Betaproteobacteria,4AATX@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
ZZS3_k127_4135764_0	365046.Rta_32050	8.669e-219	683.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,4AA4E@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
ZZS3_k127_4135764_5	365044.Pnap_3255	9.976e-103	340.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,4A9JM@80864|Comamonadaceae	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
ZZS3_k127_4135764_1	365046.Rta_32010	4.383e-173	565.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,4ACKS@80864|Comamonadaceae	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
ZZS3_k127_4135764_2	365046.Rta_32000	4.56e-157	504.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS3_k127_4135764_3	296591.Bpro_3891	3.965e-139	444.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS3_k127_4148883_5	420662.Mpe_A1525	3.474e-17	83.0	COG3064@1|root,COG4147@1|root,COG3064@2|Bacteria,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,1KJ8P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP_1	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
ZZS3_k127_4148883_3	1265502.KB905935_gene3028	5.012e-39	154.0	COG4327@1|root,COG4327@2|Bacteria,1NQBY@1224|Proteobacteria,2VV4C@28216|Betaproteobacteria,4AFHH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
ZZS3_k127_4148883_2	1265502.KB905935_gene3029	2e-71	251.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria,4AEDK@80864|Comamonadaceae	28216|Betaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
ZZS3_k127_4148883_4	1458275.AZ34_12320	6.11e-29	119.0	2E807@1|root,332EI@2|Bacteria,1NAEI@1224|Proteobacteria,2VVPC@28216|Betaproteobacteria,4AFD7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4148883_0	358220.C380_08210	5.095e-314	974.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,4AA9Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	dhlC	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
ZZS3_k127_4148883_6	935863.AWZR01000005_gene2426	6.562e-14	78.0	2E56W@1|root,33I8C@2|Bacteria,1NIND@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4148883_1	1157708.KB907456_gene2356	2.19e-263	813.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,4AA18@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS3_k127_4187021_11	296591.Bpro_3492	3.515e-41	156.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,4ACXX@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
ZZS3_k127_4187021_0	864051.BurJ1DRAFT_4349	0.0	1664.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,1KK5F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
ZZS3_k127_4187021_5	358220.C380_15015	2.177e-146	471.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,4ABW8@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	PFAM peptidase S58 DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
ZZS3_k127_4187021_1	365046.Rta_11670	1.341e-203	658.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,4A9YB@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
ZZS3_k127_4187021_3	887062.HGR_08324	2.531e-188	606.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,4ABNC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_4187021_10	543913.D521_1840	8.442e-48	178.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VRCB@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctQ	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_4187021_2	1458275.AZ34_00810	3.915e-192	607.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,4ABCI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_4187021_7	365046.Rta_17090	1.336e-67	242.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_4187021_12	1054213.HMPREF9946_00892	1.444e-36	147.0	COG1802@1|root,COG1802@2|Bacteria,1RJ47@1224|Proteobacteria,2UEJJ@28211|Alphaproteobacteria,2JXTQ@204441|Rhodospirillales	204441|Rhodospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_4187021_8	588932.JHOF01000005_gene2184	4.254e-55	197.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria,2KIY4@204458|Caulobacterales	204458|Caulobacterales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS3_k127_4187021_9	1500897.JQNA01000002_gene4281	1.91e-48	182.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,1K7SH@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4187021_6	614083.AWQR01000005_gene1168	2.112e-98	348.0	COG1231@1|root,COG1231@2|Bacteria,1NVGR@1224|Proteobacteria,2VJU0@28216|Betaproteobacteria,4AB24@80864|Comamonadaceae	28216|Betaproteobacteria	E	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
ZZS3_k127_4187021_4	365046.Rta_11580	2.657e-169	533.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,4A9S7@80864|Comamonadaceae	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
ZZS3_k127_4200073_3	365046.Rta_04130	1.252e-144	461.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,4A9PE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
ZZS3_k127_4200073_5	365046.Rta_02920	1.513e-114	376.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,4ADS8@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_4200073_6	365046.Rta_02930	3.289e-81	280.0	2CDFS@1|root,32RXQ@2|Bacteria,1N09V@1224|Proteobacteria,2VR7P@28216|Betaproteobacteria,4AE2J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2946)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2944
ZZS3_k127_4200073_4	365046.Rta_02940	5.359e-127	410.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2VHQA@28216|Betaproteobacteria,4A9JI@80864|Comamonadaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_4200073_1	365046.Rta_02970	1.159e-302	962.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4ABGN@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM glucose-methanol-choline oxidoreductase	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
ZZS3_k127_4200073_7	365046.Rta_25030	0.0006651	42.0	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VTDX@28216|Betaproteobacteria,4ADXM@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_4200073_0	365046.Rta_02980	6.198e-307	945.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2VI0N@28216|Betaproteobacteria,4A9T8@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_4200073_2	381666.H16_B0988	1.693e-164	525.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,2VJHM@28216|Betaproteobacteria,1K46N@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
ZZS3_k127_4217283_1	296591.Bpro_4727	6.414e-167	551.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,4ACDU@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM NnrS family protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
ZZS3_k127_4217283_2	296591.Bpro_4726	1.561e-127	428.0	COG4243@1|root,COG4243@2|Bacteria,1MW9C@1224|Proteobacteria,2VPG2@28216|Betaproteobacteria,4AIG6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4217283_6	296591.Bpro_4725	2.894e-31	143.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VUA0@28216|Betaproteobacteria,4AIJU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
ZZS3_k127_4217283_4	296591.Bpro_4724	3.519e-63	220.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VU41@28216|Betaproteobacteria,4AEC9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
ZZS3_k127_4217283_0	859657.RPSI07_3196	0.0	1244.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,1K467@119060|Burkholderiaceae	28216|Betaproteobacteria	P	nitric oxide reductase	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
ZZS3_k127_4217283_5	1217718.ALOU01000025_gene4186	1.047e-35	138.0	COG4309@1|root,COG4309@2|Bacteria,1NCXM@1224|Proteobacteria,2VW64@28216|Betaproteobacteria,1K9HE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
ZZS3_k127_4217283_3	296591.Bpro_0042	2.658e-70	242.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,4AENF@80864|Comamonadaceae	28216|Betaproteobacteria	T	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_4226640_8	365046.Rta_18340	1.625e-136	438.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,4AACI@80864|Comamonadaceae	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
ZZS3_k127_4226640_16	420662.Mpe_A2264	1.23e-60	213.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,1KM3K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
ZZS3_k127_4226640_11	365046.Rta_18350	2.958e-102	338.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,4AAJV@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, Rrf2 family	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
ZZS3_k127_4226640_2	365046.Rta_18360	2.08e-243	754.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,4AABE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS3_k127_4226640_14	1504672.669787077	8.805e-72	244.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,4ADIW@80864|Comamonadaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
ZZS3_k127_4226640_15	1123504.JQKD01000031_gene4517	1.057e-62	217.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,4ADXX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
ZZS3_k127_4226640_13	365046.Rta_18390	1.256e-73	254.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,4ADJR@80864|Comamonadaceae	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
ZZS3_k127_4226640_0	365046.Rta_18400	9.65e-307	950.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,4A9TW@80864|Comamonadaceae	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
ZZS3_k127_4226640_17	614083.AWQR01000035_gene3624	6.202e-52	208.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,4AE6C@80864|Comamonadaceae	28216|Betaproteobacteria	C	Ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
ZZS3_k127_4226640_7	365046.Rta_18420	6.978e-143	458.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,4ACX9@80864|Comamonadaceae	28216|Betaproteobacteria	G	Isocitrate lyase and phosphorylmutase	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
ZZS3_k127_4226640_4	365046.Rta_18430	1.812e-206	653.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VINH@28216|Betaproteobacteria,4AB8Y@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
ZZS3_k127_4226640_1	365046.Rta_18440	3.05e-297	923.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2VJZV@28216|Betaproteobacteria,4ABSY@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
ZZS3_k127_4226640_12	365046.Rta_18450	3.53e-76	258.0	COG0066@1|root,COG0066@2|Bacteria,1RBRQ@1224|Proteobacteria,2VQ2Z@28216|Betaproteobacteria,4ADUE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the LeuD family	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
ZZS3_k127_4226640_3	365046.Rta_18460	1.986e-215	674.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VJNE@28216|Betaproteobacteria,4ACWM@80864|Comamonadaceae	28216|Betaproteobacteria	C	Homoaconitate hydratase family protein	leuC1	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
ZZS3_k127_4226640_6	365046.Rta_18470	1.586e-162	521.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4226640_5	365046.Rta_18480	1.35e-169	556.0	COG2079@1|root,COG2079@2|Bacteria,1NQHH@1224|Proteobacteria,2W1RY@28216|Betaproteobacteria,4AHCP@80864|Comamonadaceae	28216|Betaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
ZZS3_k127_4226640_10	365046.Rta_18490	8.786e-113	372.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VKKX@28216|Betaproteobacteria,4AB5R@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_4226640_9	365046.Rta_18500	8.574e-124	400.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2VMBS@28216|Betaproteobacteria,4ABHD@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.22	ko:K01995,ko:K10822	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_4237989_1	365046.Rta_25500	1.893e-281	876.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2VJEU@28216|Betaproteobacteria,4ABDP@80864|Comamonadaceae	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
ZZS3_k127_4237989_2	535289.Dtpsy_0522	1.556e-99	332.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VP1R@28216|Betaproteobacteria,4ADBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_4237989_0	365046.Rta_25380	0.0	1963.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,4ACU7@80864|Comamonadaceae	28216|Betaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
ZZS3_k127_4237989_3	614083.AWQR01000001_gene3031	7.457e-73	265.0	COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
ZZS3_k127_4237989_4	243090.RB11955	5.705e-06	59.0	COG0515@1|root,COG0515@2|Bacteria,2IXP6@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_4243756_7	1268622.AVS7_00076	2.502e-28	114.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VIJU@28216|Betaproteobacteria,4AB4R@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
ZZS3_k127_4243756_0	365046.Rta_09140	0.0	1427.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,4AAU6@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
ZZS3_k127_4243756_8	296591.Bpro_3954	7.797e-14	73.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria,4AIRC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
ZZS3_k127_4243756_1	365046.Rta_09150	2.079e-225	703.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,4AAAT@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_4243756_2	614083.AWQR01000001_gene3103	3.758e-134	433.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,2VKQ9@28216|Betaproteobacteria,4ABVT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ZZS3_k127_4243756_4	365046.Rta_09160	4.265e-104	358.0	COG1946@1|root,COG4757@1|root,COG1946@2|Bacteria,COG4757@2|Bacteria,1QTZJ@1224|Proteobacteria,2VJX7@28216|Betaproteobacteria,4A9VP@80864|Comamonadaceae	28216|Betaproteobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
ZZS3_k127_4243756_3	365046.Rta_09170	3.101e-127	413.0	COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2VIQH@28216|Betaproteobacteria,4ACY5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_4243756_6	365046.Rta_09180	1.577e-89	310.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,2WFRW@28216|Betaproteobacteria,4ADQJ@80864|Comamonadaceae	28216|Betaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
ZZS3_k127_4243756_5	365046.Rta_09190	7.554e-104	351.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2VJC1@28216|Betaproteobacteria,4AA2P@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_4247553_6	1123504.JQKD01000013_gene1082	4.683e-21	93.0	COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,2VI96@28216|Betaproteobacteria,4ABMV@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.12.7	ko:K18068	ko00624,ko01100,ko01120,ko01220,map00624,map01100,map01120,map01220	M00623	R03630	RC00951	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
ZZS3_k127_4247553_3	1123504.JQKD01000013_gene1083	1.599e-129	424.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2VH98@28216|Betaproteobacteria,4ADC3@80864|Comamonadaceae	28216|Betaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.1.1.404	ko:K21607	ko00361,ko01100,ko01120,map00361,map01100,map01120	-	R11585	-	ko00000,ko00001,ko01000	-	-	-	Fer2,NAD_binding_1
ZZS3_k127_4247553_2	296591.Bpro_0198	4.869e-140	452.0	COG3181@1|root,COG3181@2|Bacteria,1Q5FF@1224|Proteobacteria,2VIJ9@28216|Betaproteobacteria,4ABI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4247553_4	1123504.JQKD01000013_gene1085	7.446e-107	359.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VJXG@28216|Betaproteobacteria,4AC6Z@80864|Comamonadaceae	28216|Betaproteobacteria	G	Class II aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
ZZS3_k127_4247553_1	365046.Rta_01020	2.587e-149	479.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,4ABEV@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_4247553_0	1123504.JQKD01000009_gene2212	1.557e-195	619.0	COG0402@1|root,COG0402@2|Bacteria,1R2YU@1224|Proteobacteria,2VIVA@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_4247553_5	1123504.JQKD01000009_gene2213	7.311e-29	119.0	COG0730@1|root,COG0730@2|Bacteria,1RACQ@1224|Proteobacteria,2VQX5@28216|Betaproteobacteria,4AGA6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_4331299_1	365046.Rta_06810	4.412e-274	846.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,4AAGT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
ZZS3_k127_4331299_5	365046.Rta_06800	2.894e-117	390.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,2VKBJ@28216|Betaproteobacteria,4AEA1@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_2,Peptidase_S41
ZZS3_k127_4331299_6	365046.Rta_06790	6.035e-116	398.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,2VI3C@28216|Betaproteobacteria,4AARW@80864|Comamonadaceae	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
ZZS3_k127_4331299_4	365046.Rta_06770	3.998e-124	402.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VQGX@28216|Betaproteobacteria,4ADSX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase C26	puuD	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
ZZS3_k127_4331299_2	365046.Rta_06760	1.354e-178	563.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,4A9W4@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4331299_3	543728.Vapar_4692	2.242e-164	524.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VMNH@28216|Betaproteobacteria,4ABTU@80864|Comamonadaceae	28216|Betaproteobacteria	BQ	Histone deacetylase superfamily	aphA1	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
ZZS3_k127_4331299_7	365046.Rta_06540	4.723e-37	159.0	COG3637@1|root,COG3637@2|Bacteria,1NC11@1224|Proteobacteria,2VX0W@28216|Betaproteobacteria,4AIGW@80864|Comamonadaceae	28216|Betaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
ZZS3_k127_4331299_0	365046.Rta_06730	0.0	2441.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,4AAZM@80864|Comamonadaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS3_k127_433580_3	365046.Rta_00640	6.782e-55	194.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VI89@28216|Betaproteobacteria,4AB74@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
ZZS3_k127_433580_1	365046.Rta_00620	7.31e-201	629.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,4A9SH@80864|Comamonadaceae	28216|Betaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	nemA	GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
ZZS3_k127_433580_0	1301098.PKB_4848	2.162e-249	790.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	P-type atpase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
ZZS3_k127_433580_2	338969.Rfer_0023	5.111e-69	241.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,4AEND@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM Cu(I)-responsive transcriptional regulator	cueR	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind
ZZS3_k127_433580_4	365046.Rta_00500	2.087e-32	132.0	2DG9F@1|root,32U6V@2|Bacteria,1N0HX@1224|Proteobacteria,2VTXA@28216|Betaproteobacteria,4AF33@80864|Comamonadaceae	28216|Betaproteobacteria	S	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
ZZS3_k127_4351918_3	1144342.PMI40_00599	8.944e-105	348.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2VME1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_2
ZZS3_k127_4351918_1	296591.Bpro_3516	2.294e-165	528.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM8R@28216|Betaproteobacteria,4AD62@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4351918_0	999541.bgla_2g11720	4.193e-232	748.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,1K0EB@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	-	-	4.2.1.42,4.2.1.7,4.4.1.24	ko:K01685,ko:K01708,ko:K16846	ko00040,ko00053,ko00270,ko01100,map00040,map00053,map00270,map01100	M00631	R01540,R05608,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ZZS3_k127_4351918_2	1453503.AU05_14300	5.023e-153	493.0	COG3970@1|root,COG3970@2|Bacteria,1MVA2@1224|Proteobacteria,1S18A@1236|Gammaproteobacteria,1YJ88@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_4351918_4	1175306.GWL_27390	8.112e-52	192.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2VP3Y@28216|Betaproteobacteria,478NQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_4351918_5	1218075.BAYA01000010_gene3215	2.591e-39	153.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2VT16@28216|Betaproteobacteria,1K73G@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD/TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS3_k127_4351918_6	395495.Lcho_1937	1.214e-20	92.0	COG0848@1|root,COG0848@2|Bacteria,1RH4U@1224|Proteobacteria,2VSF4@28216|Betaproteobacteria,1KM48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS3_k127_4387559_13	1157708.KB907451_gene4889	2.312e-13	73.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,2VK3C@28216|Betaproteobacteria,4AC81@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_4387559_2	365046.Rta_37140	3.084e-170	541.0	COG1633@1|root,COG1633@2|Bacteria,1MXX8@1224|Proteobacteria,2VI3H@28216|Betaproteobacteria,4ACR1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4387559_7	365046.Rta_37160	4.046e-82	286.0	COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,2VQHV@28216|Betaproteobacteria,4ADQF@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
ZZS3_k127_4387559_3	365046.Rta_37240	3.706e-111	361.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,4ABQB@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
ZZS3_k127_4387559_0	365046.Rta_37250	7.731e-273	846.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,4AABF@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
ZZS3_k127_4387559_6	365046.Rta_37270	2.318e-84	300.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,4ABM5@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM YaeQ family protein	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
ZZS3_k127_4387559_11	296591.Bpro_4663	9.946e-41	163.0	2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,2VV11@28216|Betaproteobacteria,4AF6M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
ZZS3_k127_4387559_8	296591.Bpro_4664	8.288e-72	244.0	COG3313@1|root,COG3313@2|Bacteria,1N711@1224|Proteobacteria,2VW2B@28216|Betaproteobacteria,4AE63@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3717)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289,DUF3717
ZZS3_k127_4387559_4	365044.Pnap_3917	6.814e-100	344.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2VM9Q@28216|Betaproteobacteria,4AC6W@80864|Comamonadaceae	28216|Betaproteobacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
ZZS3_k127_4387559_10	397945.Aave_4674	1.897e-41	156.0	2BVJJ@1|root,32QXH@2|Bacteria,1MYKH@1224|Proteobacteria,2VT7V@28216|Betaproteobacteria,4AF3G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4387559_12	123899.JPQP01000021_gene3590	1.124e-24	107.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,3T49W@506|Alcaligenaceae	28216|Betaproteobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
ZZS3_k127_4387559_1	365046.Rta_37300	3.133e-200	636.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,4AAZX@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase M48, Ste24p	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
ZZS3_k127_4387559_5	365046.Rta_37310	7.02e-93	318.0	28IZ5@1|root,2Z8WP@2|Bacteria,1R6WI@1224|Proteobacteria,2VPVV@28216|Betaproteobacteria,4AC3A@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4387559_9	365044.Pnap_3920	4.541e-70	240.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,4ADG7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
ZZS3_k127_4432470_8	365046.Rta_32790	1.052e-19	88.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2VI6J@28216|Betaproteobacteria,4A9XB@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
ZZS3_k127_4432470_0	338969.Rfer_3380	2.751e-244	764.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJ7X@28216|Betaproteobacteria,4A9YV@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
ZZS3_k127_4432470_1	1276756.AUEX01000001_gene1041	3.491e-198	639.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VHZA@28216|Betaproteobacteria,4AAWG@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	urtC	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
ZZS3_k127_4432470_2	296591.Bpro_1396	6.784e-147	489.0	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2VIX4@28216|Betaproteobacteria,4A9QH@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC transporter related	urtD	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_4432470_4	296591.Bpro_1397	1.396e-126	407.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2VJUP@28216|Betaproteobacteria,4A9PJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	ABC transporter, ATP-binding protein	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
ZZS3_k127_4432470_7	365046.Rta_32730	6.039e-37	161.0	2EB3M@1|root,3354C@2|Bacteria,1N9Z4@1224|Proteobacteria,2VW86@28216|Betaproteobacteria,4AFCZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4432470_5	614083.AWQR01000002_gene2988	3.186e-118	385.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2VHXH@28216|Betaproteobacteria,4ACQ2@80864|Comamonadaceae	28216|Betaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
ZZS3_k127_4432470_3	864051.BurJ1DRAFT_4058	6.403e-133	427.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2VMJ5@28216|Betaproteobacteria,1KJ9M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ZZS3_k127_4432470_6	1157708.KB907460_gene1399	5.215e-71	240.0	COG1116@1|root,COG1116@2|Bacteria,1P4HB@1224|Proteobacteria,2VISQ@28216|Betaproteobacteria,4A9SC@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
ZZS3_k127_4443006_1	365044.Pnap_1701	1.177e-243	762.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,4AA75@80864|Comamonadaceae	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
ZZS3_k127_4443006_3	365046.Rta_23050	2.787e-106	346.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,4AA0S@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
ZZS3_k127_4443006_2	543728.Vapar_2359	8.818e-187	591.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,4AAXS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
ZZS3_k127_4443006_0	365046.Rta_23030	1.836e-278	864.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,4AABN@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
ZZS3_k127_4443006_4	338969.Rfer_1700	1.925e-20	91.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,4ADYB@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
ZZS3_k127_4459839_13	1040989.AWZU01000009_gene1109	5.215e-07	51.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1MWIC@1224|Proteobacteria,2TRIA@28211|Alphaproteobacteria,3JS62@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR_2
ZZS3_k127_4459839_10	864069.MicloDRAFT_00019980	9.069e-77	268.0	COG0697@1|root,COG0697@2|Bacteria,1PB22@1224|Proteobacteria,2U158@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_36650	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_4459839_11	365046.Rta_19220	1.744e-74	269.0	COG2059@1|root,COG2059@2|Bacteria,1MZHQ@1224|Proteobacteria,2VQS5@28216|Betaproteobacteria,4ADPS@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
ZZS3_k127_4459839_9	1504672.669782974	1.642e-81	286.0	COG2059@1|root,COG2059@2|Bacteria,1RAZW@1224|Proteobacteria,2VQ9R@28216|Betaproteobacteria,4ADJ9@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
ZZS3_k127_4459839_12	338969.Rfer_2233	2.431e-43	172.0	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,2VSQX@28216|Betaproteobacteria,4AEPW@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4459839_4	1458275.AZ34_09345	9.24e-128	414.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,4AAVB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
ZZS3_k127_4459839_6	1217718.ALOU01000047_gene3725	1.181e-95	324.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKW3@28216|Betaproteobacteria,1JZUR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4459839_3	1207063.P24_07784	1.05e-137	442.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	tauD	-	1.14.11.17	ko:K03119,ko:K22303	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
ZZS3_k127_4459839_5	365046.Rta_19170	5.221e-119	385.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,4AAT4@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM ABC transporter related	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_4459839_8	365046.Rta_19160	4.523e-90	309.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria,4ADGS@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
ZZS3_k127_4459839_2	365046.Rta_19150	7.974e-156	510.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,4AAMW@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
ZZS3_k127_4459839_1	365046.Rta_19080	2.75e-215	677.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2VHNW@28216|Betaproteobacteria,4AAB6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Cys Met metabolism pyridoxal-phosphate-dependent	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_4459839_7	1123504.JQKD01000031_gene4571	5.885e-94	331.0	COG2236@1|root,COG2236@2|Bacteria,1R675@1224|Proteobacteria,2VPZG@28216|Betaproteobacteria,4AA1G@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM Phosphoribosyltransferase	gpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
ZZS3_k127_4459839_0	365046.Rta_19050	3.231e-272	839.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,4AAS1@80864|Comamonadaceae	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
ZZS3_k127_4466823_0	365046.Rta_06730	0.0	1033.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,4AAZM@80864|Comamonadaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS3_k127_4466823_2	365046.Rta_06720	1.14e-180	575.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VI4C@28216|Betaproteobacteria,4ABPE@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_4466823_3	748247.AZKH_0736	1.172e-95	327.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4466823_4	748247.AZKH_0736	1.737e-22	100.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4466823_5	1268622.AVS7_01496	4.122e-10	62.0	2EMT0@1|root,33FFE@2|Bacteria,1NGBN@1224|Proteobacteria,2VXN4@28216|Betaproteobacteria,4AFTP@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4466823_1	365046.Rta_06700	1.475e-309	959.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,4AB0A@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	General substrate transporter	proP_2	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
ZZS3_k127_457399_1	338969.Rfer_2141	7.207e-71	241.0	COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,2VREZ@28216|Betaproteobacteria,4ADX9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
ZZS3_k127_457399_0	365046.Rta_24620	3.334e-125	411.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2VKIZ@28216|Betaproteobacteria,4A9UH@80864|Comamonadaceae	28216|Betaproteobacteria	C	nitroreductase	nfnB	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
ZZS3_k127_457399_2	232721.Ajs_0254	3.315e-29	124.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,4AFCQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
ZZS3_k127_457399_3	1268622.AVS7_04598	1.85e-20	93.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,2VI3Y@28216|Betaproteobacteria,4AB88@80864|Comamonadaceae	28216|Betaproteobacteria	P	Putative citrate transport	arsB	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
ZZS3_k127_4621705_0	365046.Rta_23900	0.0	1299.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,4AAPA@80864|Comamonadaceae	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS3_k127_4621705_5	365046.Rta_23910	1.193e-48	180.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,2VX7B@28216|Betaproteobacteria,4AFCK@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4621705_1	365046.Rta_23930	6.23e-201	634.0	COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2VIVN@28216|Betaproteobacteria,4AC5F@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM monooxygenase FAD-binding	-	-	1.14.13.218	ko:K20940	ko00405,ko01130,map00405,map01130	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_4621705_2	365046.Rta_23940	1.039e-152	488.0	COG3181@1|root,COG3181@2|Bacteria,1P25R@1224|Proteobacteria,2VMA6@28216|Betaproteobacteria,4ABJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4621705_4	296591.Bpro_2197	3.3e-63	224.0	COG1846@1|root,COG1846@2|Bacteria,1RM4H@1224|Proteobacteria,2VSUM@28216|Betaproteobacteria,4AEF8@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_4621705_3	365046.Rta_23960	1.484e-118	385.0	COG3181@1|root,COG3181@2|Bacteria,1N00G@1224|Proteobacteria,2VN46@28216|Betaproteobacteria,4ABNY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4622839_4	365046.Rta_05570	5.25e-98	322.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,4ACSM@80864|Comamonadaceae	28216|Betaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
ZZS3_k127_4622839_2	365046.Rta_05580	1.175e-124	405.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,4ACJ2@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS3_k127_4622839_1	365046.Rta_05590	1.563e-127	414.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,4A9K3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
ZZS3_k127_4622839_6	365046.Rta_05620	2.776e-62	217.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2VSPA@28216|Betaproteobacteria,4ADZT@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcription regulator MerR DNA binding	zntR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
ZZS3_k127_4622839_7	398578.Daci_5992	2.561e-58	214.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2VRED@28216|Betaproteobacteria,4ADYC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_4622839_0	365046.Rta_05640	3.293e-240	744.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHD3@28216|Betaproteobacteria,4A9Q4@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4622839_3	1123504.JQKD01000039_gene1104	5.782e-100	346.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VIBS@28216|Betaproteobacteria,4AANR@80864|Comamonadaceae	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Pro_CA
ZZS3_k127_4622839_5	1157708.KB907473_gene1258	6.369e-74	249.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,4ABTR@80864|Comamonadaceae	28216|Betaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
ZZS3_k127_4646431_2	1157708.KB907451_gene4656	1.84e-95	313.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,4AAZB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	dld	-	1.1.2.4,1.1.5.12	ko:K00102,ko:K03777	ko00620,ko01120,map00620,map01120	-	R00197,R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_4646431_3	365046.Rta_00830	5.791e-93	314.0	COG1802@1|root,COG1802@2|Bacteria,1RE3W@1224|Proteobacteria,2VR3G@28216|Betaproteobacteria,4ADWC@80864|Comamonadaceae	28216|Betaproteobacteria	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_4646431_1	365046.Rta_00820	1.764e-140	451.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VIGV@28216|Betaproteobacteria,4AB4M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4646431_0	365046.Rta_00810	2.148e-145	476.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VN65@28216|Betaproteobacteria,4A9Q0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
ZZS3_k127_4651542_6	1157708.KB907463_gene796	2.415e-156	498.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VKPA@28216|Betaproteobacteria,4A9QB@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
ZZS3_k127_4651542_1	1242864.D187_008895	4.843e-233	750.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,42YKP@68525|delta/epsilon subdivisions,2WUQ9@28221|Deltaproteobacteria,2YWFW@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K02056,ko:K05776,ko:K10441,ko:K10539,ko:K10548	ko02010,map02010	M00189,M00212,M00213,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2,3.A.1.2.5	-	-	ABC_tran
ZZS3_k127_4651542_2	365046.Rta_07270	3.498e-213	667.0	COG1940@1|root,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,2WG1U@28216|Betaproteobacteria,4ABZX@80864|Comamonadaceae	28216|Betaproteobacteria	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
ZZS3_k127_4651542_4	365046.Rta_07260	1.566e-164	529.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,4AA0T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
ZZS3_k127_4651542_7	397945.Aave_4225	5.225e-103	344.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,4AB7N@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_4651542_10	365046.Rta_07240	9.754e-61	221.0	COG1539@1|root,COG1539@2|Bacteria,1RD8Q@1224|Proteobacteria,2VR6E@28216|Betaproteobacteria,4ADXQ@80864|Comamonadaceae	28216|Betaproteobacteria	H	dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
ZZS3_k127_4651542_5	365046.Rta_07200	7.208e-163	517.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,4AAVN@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
ZZS3_k127_4651542_9	365046.Rta_07190	1.639e-68	246.0	2C0PG@1|root,330E3@2|Bacteria,1RA6M@1224|Proteobacteria,2VTJ7@28216|Betaproteobacteria,4AEHB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
ZZS3_k127_4651542_8	358220.C380_21300	3.202e-83	282.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,4A9S9@80864|Comamonadaceae	28216|Betaproteobacteria	G	phosphoglycerate mutase	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
ZZS3_k127_4651542_3	365046.Rta_07170	1.255e-191	606.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2VIUU@28216|Betaproteobacteria,4ACPR@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM alanine racemase domain protein	-	-	4.1.2.42	ko:K19967	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
ZZS3_k127_4651542_0	595537.Varpa_5280	1.642e-253	793.0	COG3000@1|root,COG3714@1|root,COG3000@2|Bacteria,COG3714@2|Bacteria,1NR7X@1224|Proteobacteria,2VJ4E@28216|Betaproteobacteria,4ABMB@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase,YhhN
ZZS3_k127_4681062_1	365046.Rta_36950	1.195e-297	936.0	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,2VNCR@28216|Betaproteobacteria,4AC9D@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
ZZS3_k127_4681062_2	365046.Rta_36960	3.008e-167	529.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,4A9SD@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
ZZS3_k127_4681062_0	535289.Dtpsy_3355	6.583e-317	979.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,4A9UJ@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
ZZS3_k127_4681062_4	365046.Rta_36980	4.976e-47	182.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,4AEH1@80864|Comamonadaceae	28216|Betaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
ZZS3_k127_4681062_3	365046.Rta_36990	1.461e-76	260.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,4AC8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
ZZS3_k127_468168_1	365046.Rta_24610	1.434e-216	675.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,2VI3Y@28216|Betaproteobacteria,4AB88@80864|Comamonadaceae	28216|Betaproteobacteria	P	Putative citrate transport	arsB	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
ZZS3_k127_468168_2	365046.Rta_24600	3.852e-174	569.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,4AC7E@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_468168_0	365046.Rta_24590	6.097e-218	700.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,4AATV@80864|Comamonadaceae	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
ZZS3_k127_468168_3	358220.C380_13705	3.706e-160	517.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria,4A9QI@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_468168_4	365046.Rta_24560	1.871e-153	488.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,4A9W2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS3_k127_468168_9	264198.Reut_A0908	2.019e-79	276.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,2VNH9@28216|Betaproteobacteria,1KABJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
ZZS3_k127_468168_8	365046.Rta_24540	4.631e-90	314.0	2BUI6@1|root,32PUF@2|Bacteria,1PJFC@1224|Proteobacteria,2VSBG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3445)	-	-	1.14.13.238	ko:K22342	-	-	-	-	ko00000,ko01000	-	-	-	DUF3445
ZZS3_k127_468168_7	595537.Varpa_1954	5.242e-96	324.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,4AAGC@80864|Comamonadaceae	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
ZZS3_k127_468168_5	365046.Rta_24520	2.695e-128	421.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,4AA1D@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
ZZS3_k127_468168_6	365046.Rta_24510	3.437e-128	413.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,4ABCV@80864|Comamonadaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
ZZS3_k127_4726446_10	1123504.JQKD01000005_gene4796	2.219e-15	75.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,4AA6R@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
ZZS3_k127_4726446_5	365046.Rta_15720	1.54e-161	520.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,4AAI8@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM amine oxidase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
ZZS3_k127_4726446_9	365046.Rta_15710	4.425e-108	353.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,2VR50@28216|Betaproteobacteria,4ADVD@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
ZZS3_k127_4726446_4	365046.Rta_15700	3.422e-171	544.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,4ABIW@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
ZZS3_k127_4726446_6	365046.Rta_15690	3.82e-152	485.0	COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2VKCZ@28216|Betaproteobacteria,4AC2B@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_4726446_0	1458275.AZ34_02665	1.885e-209	672.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2VJ7U@28216|Betaproteobacteria,4ABSH@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
ZZS3_k127_4726446_1	365046.Rta_15670	3.079e-189	596.0	COG4177@1|root,COG4177@2|Bacteria,1MZDJ@1224|Proteobacteria,2VJSE@28216|Betaproteobacteria,4AAFD@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_4726446_2	365046.Rta_15660	4.908e-177	571.0	COG0559@1|root,COG0559@2|Bacteria,1MVZ5@1224|Proteobacteria,2VJCG@28216|Betaproteobacteria,4AC0G@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_4726446_8	365046.Rta_15650	1.365e-131	423.0	COG0410@1|root,COG0410@2|Bacteria,1MW9R@1224|Proteobacteria,2VNG7@28216|Betaproteobacteria,4AASF@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_4726446_7	365046.Rta_15640	1.129e-135	436.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VI76@28216|Betaproteobacteria,4ABC1@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_4726446_3	1276756.AUEX01000010_gene1583	3.95e-173	544.0	COG0683@1|root,COG0683@2|Bacteria,1N1MX@1224|Proteobacteria,2VJMT@28216|Betaproteobacteria,4AC97@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_4740066_5	595537.Varpa_1325	2.081e-75	256.0	COG2151@1|root,COG3677@1|root,COG2151@2|Bacteria,COG3677@2|Bacteria,1RF3S@1224|Proteobacteria,2VQI0@28216|Betaproteobacteria,4AE5G@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
ZZS3_k127_4740066_0	1157708.KB907452_gene3759	1.175e-192	615.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,2VKK1@28216|Betaproteobacteria,4AAJ3@80864|Comamonadaceae	28216|Betaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
ZZS3_k127_4740066_4	1123504.JQKD01000013_gene1019	6.47e-79	288.0	COG1309@1|root,COG1309@2|Bacteria,1QYD4@1224|Proteobacteria,2VMMD@28216|Betaproteobacteria,4ADMH@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	paaR	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
ZZS3_k127_4740066_3	365046.Rta_16840	9.326e-105	355.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,2VKYT@28216|Betaproteobacteria,4ACY1@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Pseudouridine synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
ZZS3_k127_4740066_6	1219080.VEZ01S_05_00500	4.646e-14	80.0	COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1XXCR@135623|Vibrionales	135623|Vibrionales	S	Predicted membrane protein (DUF2061)	VP2647	-	-	-	-	-	-	-	-	-	-	-	DUF2061
ZZS3_k127_4740066_1	296591.Bpro_4733	3.536e-132	427.0	COG0583@1|root,COG0583@2|Bacteria,1RJNA@1224|Proteobacteria,2VZ7R@28216|Betaproteobacteria,4AH05@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_4740066_2	296591.Bpro_4734	1.884e-109	357.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
ZZS3_k127_47512_12	365046.Rta_36120	6.356e-43	161.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,4ADGY@80864|Comamonadaceae	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
ZZS3_k127_47512_13	887062.HGR_09064	2.016e-28	114.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,4AFGA@80864|Comamonadaceae	28216|Betaproteobacteria	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
ZZS3_k127_47512_4	365046.Rta_36140	5.623e-98	321.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,4AB1M@80864|Comamonadaceae	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
ZZS3_k127_47512_9	365046.Rta_36150	4.069e-56	199.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,4AE21@80864|Comamonadaceae	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
ZZS3_k127_47512_5	358220.C380_21885	5.043e-92	304.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,4AC4Q@80864|Comamonadaceae	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
ZZS3_k127_47512_6	232721.Ajs_0395	8.155e-72	243.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,4ADJT@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
ZZS3_k127_47512_11	1458275.AZ34_17325	1.808e-49	177.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,4AEBE@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
ZZS3_k127_47512_3	365046.Rta_36190	1.956e-104	341.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,4A9NY@80864|Comamonadaceae	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
ZZS3_k127_47512_10	365046.Rta_36200	2.769e-50	186.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,4AEBZ@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
ZZS3_k127_47512_8	365046.Rta_36210	5.17e-69	237.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,4ADWB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
ZZS3_k127_47512_0	365046.Rta_36220	8.245e-257	804.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,4AA35@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
ZZS3_k127_47512_1	614083.AWQR01000009_gene528	5.727e-242	755.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,4AAE7@80864|Comamonadaceae	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
ZZS3_k127_47512_2	1122919.KB905549_gene2129	5.208e-115	382.0	COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli,26RR0@186822|Paenibacillaceae	91061|Bacilli	S	Sulfatase-modifying factor enzyme 1	pkn1	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
ZZS3_k127_47512_7	1123504.JQKD01000030_gene4637	4.579e-69	236.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2VIFW@28216|Betaproteobacteria,4AB9I@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sulfatase	atsA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
ZZS3_k127_4765701_2	365046.Rta_31740	4.071e-159	503.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,4A9NJ@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4765701_1	365046.Rta_31750	1.889e-192	608.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2VHX0@28216|Betaproteobacteria,4A9ZN@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_4765701_0	365046.Rta_31760	2.14e-207	673.0	COG1075@1|root,COG1075@2|Bacteria,1MWM9@1224|Proteobacteria,2VN20@28216|Betaproteobacteria,4ACT5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
ZZS3_k127_4765701_3	1123504.JQKD01000018_gene2038	3.746e-52	184.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,4AB9G@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
ZZS3_k127_47678_3	365046.Rta_06690	2.302e-93	314.0	COG3917@1|root,COG3917@2|Bacteria,1RJFB@1224|Proteobacteria,2VPYN@28216|Betaproteobacteria,4ACDE@80864|Comamonadaceae	28216|Betaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
ZZS3_k127_47678_6	1366050.N234_00735	1.983e-13	79.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VXYJ@28216|Betaproteobacteria,1KAEA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
ZZS3_k127_47678_4	1268622.AVS7_01501	2.146e-84	289.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2VQJW@28216|Betaproteobacteria,4ADR2@80864|Comamonadaceae	28216|Betaproteobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289,tRNA_edit
ZZS3_k127_47678_0	1504672.669784338	1.176e-163	524.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,4AAG8@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Pyruvate carboxyltransferase	hmgcL	GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
ZZS3_k127_47678_2	365046.Rta_06660	3.552e-156	500.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VIH8@28216|Betaproteobacteria,4AA4A@80864|Comamonadaceae	28216|Betaproteobacteria	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
ZZS3_k127_47678_1	358220.C380_05280	4.294e-157	507.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VMGR@28216|Betaproteobacteria	28216|Betaproteobacteria	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
ZZS3_k127_47678_5	397945.Aave_4351	1.808e-36	138.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,4ABER@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	accA1	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS3_k127_4769385_7	1268622.AVS7_00122	4.807e-48	172.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,4ACB9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
ZZS3_k127_4769385_1	338969.Rfer_0261	0.0	1224.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,2WGM2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
ZZS3_k127_4769385_6	76114.ebA4980	1.373e-63	229.0	COG5403@1|root,COG5403@2|Bacteria,1N0H4@1224|Proteobacteria,2W217@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
ZZS3_k127_4769385_5	365046.Rta_07750	6.914e-67	236.0	COG4191@1|root,COG4191@2|Bacteria,1NYMR@1224|Proteobacteria,2W3N9@28216|Betaproteobacteria,4AI1N@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4769385_0	365046.Rta_07780	0.0	1291.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_primase_S,LigD_N
ZZS3_k127_4769385_2	365046.Rta_07790	4.668e-130	424.0	COG1633@1|root,COG3861@1|root,COG1633@2|Bacteria,COG3861@2|Bacteria,1RGZG@1224|Proteobacteria,2VSVM@28216|Betaproteobacteria,4ABHC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
ZZS3_k127_4769385_3	365046.Rta_07810	9.804e-101	346.0	28IJW@1|root,2Z8KR@2|Bacteria,1R45I@1224|Proteobacteria,2VK7H@28216|Betaproteobacteria,4ADTX@80864|Comamonadaceae	28216|Betaproteobacteria	S	signal peptide protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4769385_4	232721.Ajs_0705	2.455e-88	291.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,4A9S3@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
ZZS3_k127_4865793_3	296591.Bpro_1733	5.402e-161	511.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria,4ABRX@80864|Comamonadaceae	28216|Betaproteobacteria	Q	dienelactone hydrolase	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
ZZS3_k127_4865793_7	365046.Rta_12870	1.076e-23	102.0	COG1942@1|root,COG1942@2|Bacteria,1N8I6@1224|Proteobacteria,2VW8C@28216|Betaproteobacteria,4AFEI@80864|Comamonadaceae	28216|Betaproteobacteria	G	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
ZZS3_k127_4865793_0	365046.Rta_12840	0.0	1609.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4AAFC@80864|Comamonadaceae	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
ZZS3_k127_4865793_6	365046.Rta_12830	3.848e-28	117.0	2EC30@1|root,3361Z@2|Bacteria,1NB2T@1224|Proteobacteria,2VW1B@28216|Betaproteobacteria,4AFKR@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4865793_2	358220.C380_06870	1.402e-164	527.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,4AB4K@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
ZZS3_k127_4865793_5	365046.Rta_12810	1.947e-67	237.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,4ACQQ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4865793_4	614083.AWQR01000010_gene1525	8.35e-99	350.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria,4AH9Y@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
ZZS3_k127_4865793_8	420324.KI911952_gene3300	4.414e-23	105.0	COG0457@1|root,COG0457@2|Bacteria,1N6TJ@1224|Proteobacteria,2UG5W@28211|Alphaproteobacteria,1JYPC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
ZZS3_k127_4865793_1	365046.Rta_12760	1.078e-241	752.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,4AAM8@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS3_k127_486809_0	614083.AWQR01000012_gene1344	6.523e-223	695.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VNGY@28216|Betaproteobacteria,4ADCT@80864|Comamonadaceae	28216|Betaproteobacteria	C	Phenol hydroxylase, C-terminal dimerisation domain	-	-	1.14.13.23,1.14.13.7	ko:K03380,ko:K19065	ko00362,ko00623,ko00624,ko00627,ko01120,ko01220,map00362,map00623,map00624,map00627,map01120,map01220	-	R00815,R01628,R03566	RC00046,RC00236	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Phe_hydrox_dim
ZZS3_k127_486809_6	688245.CtCNB1_3411	1.596e-48	178.0	COG1846@1|root,COG1846@2|Bacteria,1RJPG@1224|Proteobacteria,2VRN5@28216|Betaproteobacteria,4AEA2@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
ZZS3_k127_486809_3	1157708.KB907450_gene5286	5.883e-94	317.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VIZP@28216|Betaproteobacteria,4A9RC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_486809_1	595537.Varpa_2447	1.758e-127	421.0	COG2755@1|root,COG2755@2|Bacteria,1MXBN@1224|Proteobacteria,2VPAT@28216|Betaproteobacteria,4AC4T@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS3_k127_486809_2	342113.DM82_105	1.131e-116	391.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,1K13H@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
ZZS3_k127_486809_4	331869.BAL199_04959	6.659e-72	252.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2U49B@28211|Alphaproteobacteria,4BT7J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
ZZS3_k127_486809_7	1415755.JQLV01000001_gene1548	6.841e-10	62.0	COG0477@1|root,COG2814@2|Bacteria,1MVD0@1224|Proteobacteria,1RMBW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine	nepI	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015211,GO:0015858,GO:0015860,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1901264,GO:1901505,GO:1901642	-	ko:K03445	-	-	-	-	ko00000,ko02000	2.A.1.2.26	-	-	MFS_1
ZZS3_k127_486809_5	365046.Rta_08460	3.207e-55	196.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,4AE0F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
ZZS3_k127_4884435_15	391735.Veis_5012	1.998e-36	137.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,4AA59@80864|Comamonadaceae	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
ZZS3_k127_4884435_2	365046.Rta_38200	5.475e-203	641.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,4ABHN@80864|Comamonadaceae	28216|Betaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
ZZS3_k127_4884435_16	232721.Ajs_0254	1.147e-29	121.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,4AFCQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
ZZS3_k127_4884435_12	397945.Aave_0200	9.284e-79	274.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AAJP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4884435_11	1247726.MIM_c17660	1.284e-82	282.0	COG1414@1|root,COG1414@2|Bacteria,1R9EX@1224|Proteobacteria,2VQQG@28216|Betaproteobacteria,3T70W@506|Alcaligenaceae	28216|Betaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_4884435_1	640511.BC1002_3595	4.846e-229	716.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VP1G@28216|Betaproteobacteria,1K3C0@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS3_k127_4884435_8	1097668.BYI23_C002450	1.769e-101	356.0	COG1028@1|root,COG1028@2|Bacteria,1P3AE@1224|Proteobacteria,2VN49@28216|Betaproteobacteria,1KGKH@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_4884435_4	1231391.AMZF01000008_gene1571	2.652e-145	468.0	COG3485@1|root,COG3485@2|Bacteria,1QBMH@1224|Proteobacteria,2VJPE@28216|Betaproteobacteria,3T427@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Catechol dioxygenase N terminus	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
ZZS3_k127_4884435_6	296591.Bpro_0971	7.755e-131	437.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VH5E@28216|Betaproteobacteria,4ABW1@80864|Comamonadaceae	28216|Betaproteobacteria	Q	TIGRFAM 2-oxo-hepta-3-ene-1,7-dioic acid hydratase	-	-	-	ko:K02509	ko00350,ko01120,map00350,map01120	-	R04132,R06897	RC01615,RC02595	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_4884435_5	399795.CtesDRAFT_PD2138	2.598e-144	464.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4884435_13	365046.Rta_38190	2.257e-56	201.0	COG0664@1|root,COG0664@2|Bacteria,1RFGF@1224|Proteobacteria,2VR2U@28216|Betaproteobacteria,4AE8C@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS3_k127_4884435_14	358220.C380_23870	1.195e-53	203.0	2CGAU@1|root,30291@2|Bacteria,1RE86@1224|Proteobacteria,2VRJV@28216|Betaproteobacteria,4AE95@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4884435_10	1100720.ALKN01000033_gene735	6.497e-88	329.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2VI7G@28216|Betaproteobacteria,4ACVK@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
ZZS3_k127_4884435_0	365046.Rta_38170	3e-323	999.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,4AABC@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
ZZS3_k127_4884435_3	365046.Rta_38160	1.121e-161	514.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,4A9XD@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
ZZS3_k127_4884435_9	365046.Rta_38150	1.295e-95	325.0	COG1778@1|root,COG3117@1|root,COG1778@2|Bacteria,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,4ADJ4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
ZZS3_k127_4884435_7	365046.Rta_38130	4.844e-120	398.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,4AJYI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_4900395_1	1276756.AUEX01000024_gene74	1.889e-190	599.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,4ABI9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
ZZS3_k127_4900395_3	397945.Aave_1023	1.792e-109	367.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,4AAKT@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
ZZS3_k127_4900395_0	887062.HGR_06506	2.413e-227	721.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,4ABD8@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
ZZS3_k127_4900395_2	365046.Rta_08240	6.086e-175	555.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,4A9XW@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_4900395_4	1504672.669784115	1.706e-37	143.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,4AAWV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
ZZS3_k127_4930764_1	365046.Rta_31560	4.309e-166	527.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VK73@28216|Betaproteobacteria,4AB3Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4930764_5	365046.Rta_31570	1.757e-16	87.0	COG3637@1|root,COG3637@2|Bacteria,1MYD6@1224|Proteobacteria,2VSTV@28216|Betaproteobacteria,4AEGM@80864|Comamonadaceae	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
ZZS3_k127_4930764_3	365046.Rta_31580	1.647e-121	413.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,4AAKJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_4930764_2	365046.Rta_31590	5.494e-150	477.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,4A9JJ@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_4930764_0	365046.Rta_31600	1.272e-191	602.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,4A9UK@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_4930764_4	365046.Rta_31610	1.692e-100	329.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,4AAZF@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_4977579_2	365046.Rta_23010	3.771e-79	275.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,4ABBS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS3_k127_4977579_4	365046.Rta_26210	2.677e-51	192.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,4AEDT@80864|Comamonadaceae	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
ZZS3_k127_4977579_3	543728.Vapar_2364	1.456e-55	210.0	COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria,4ADYZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
ZZS3_k127_4977579_6	365046.Rta_22990	1.827e-40	163.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,4AE7M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
ZZS3_k127_4977579_7	365046.Rta_22980	1.882e-32	140.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWX5@28216|Betaproteobacteria,4AEYG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
ZZS3_k127_4977579_1	365046.Rta_22970	1.532e-93	314.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,4AC2F@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_4977579_0	296591.Bpro_2317	0.0	1081.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,4AAYC@80864|Comamonadaceae	28216|Betaproteobacteria	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_4977579_5	338969.Rfer_3323	3.537e-47	193.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,4AB4H@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM Acetolactate synthase, small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
ZZS3_k127_4984342_12	365046.Rta_33790	1.701e-62	219.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,4ADQI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
ZZS3_k127_4984342_9	1100721.ALKO01000021_gene797	2.895e-81	273.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,4ADKI@80864|Comamonadaceae	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
ZZS3_k127_4984342_10	365046.Rta_33810	6.462e-78	263.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2VQFV@28216|Betaproteobacteria,4ADKH@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
ZZS3_k127_4984342_6	365046.Rta_33820	1.175e-99	328.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,4ABG3@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
ZZS3_k127_4984342_8	543728.Vapar_4399	7.647e-96	317.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,2VMX3@28216|Betaproteobacteria,4ACHG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	kefF	-	1.6.5.2	ko:K00355,ko:K11746,ko:K11748	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000,ko02000	2.A.37.1.1,2.A.37.1.2	-	-	Flavodoxin_2
ZZS3_k127_4984342_0	614083.AWQR01000029_gene2136	7.716e-276	870.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,4AABC@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
ZZS3_k127_4984342_3	365046.Rta_33840	2.06e-120	392.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2VIZS@28216|Betaproteobacteria,4ACJD@80864|Comamonadaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_4984342_13	1131814.JAFO01000001_gene4139	5.867e-62	232.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2TUBI@28211|Alphaproteobacteria,3F2AF@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
ZZS3_k127_4984342_2	1100720.ALKN01000035_gene949	1.377e-130	426.0	COG3181@1|root,COG3181@2|Bacteria,1NR4F@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_4984342_4	1100720.ALKN01000035_gene950	7.761e-111	363.0	28N0F@1|root,2ZB6V@2|Bacteria,1R4J3@1224|Proteobacteria,2W16E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
ZZS3_k127_4984342_7	1231391.AMZF01000020_gene2011	8.944e-99	327.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria	1224|Proteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_4984342_1	1231391.AMZF01000020_gene2010	4.568e-224	731.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUFT@1224|Proteobacteria	1224|Proteobacteria	E	(ABC) transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_4984342_5	1231391.AMZF01000020_gene2009	1.37e-110	364.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2VPYC@28216|Betaproteobacteria,3T2PS@506|Alcaligenaceae	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_4984342_11	1231391.AMZF01000020_gene2008	1.318e-65	228.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_5046487_5	365046.Rta_15520	2.281e-64	222.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,4AEDD@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM RNA-binding S4 domain protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
ZZS3_k127_5046487_1	365046.Rta_15530	5.519e-212	669.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2WHKM@28216|Betaproteobacteria,4AJZE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
ZZS3_k127_5046487_3	296591.Bpro_2008	1.32e-102	338.0	COG0745@1|root,COG0745@2|Bacteria,1R4GB@1224|Proteobacteria,2VJDU@28216|Betaproteobacteria,4AC6K@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07774	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_5046487_2	596154.Alide2_2112	3.69e-174	551.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,4AAYT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
ZZS3_k127_5046487_4	365046.Rta_15560	6.742e-69	245.0	2C1K4@1|root,30F52@2|Bacteria,1REDQ@1224|Proteobacteria,2VRSY@28216|Betaproteobacteria,4ADXR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
ZZS3_k127_5046487_0	365046.Rta_15570	1.374e-262	816.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AA69@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
ZZS3_k127_5052404_1	365046.Rta_20150	4.083e-240	775.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_5052404_2	365046.Rta_20140	6.225e-162	518.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1R6XF@1224|Proteobacteria,2VHK6@28216|Betaproteobacteria,4AGP0@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	phcR	-	-	ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_5052404_0	365046.Rta_20120	0.0	1020.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,4A9R2@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_5052404_3	338969.Rfer_2392	1.802e-31	126.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2VI1S@28216|Betaproteobacteria,4AAZP@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_5057089_12	292415.Tbd_0033	4.949e-32	140.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria	28216|Betaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
ZZS3_k127_5057089_1	365046.Rta_23370	1.209e-233	745.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VP0K@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
ZZS3_k127_5057089_13	365046.Rta_23310	4.986e-26	115.0	2C2M8@1|root,33DV5@2|Bacteria,1NN6E@1224|Proteobacteria,2VYS1@28216|Betaproteobacteria,4AFTN@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5057089_15	1408164.MOLA814_00089	1.301e-06	51.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,1KPNU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
ZZS3_k127_5057089_0	365046.Rta_23300	3.704e-275	857.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,4ABHQ@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
ZZS3_k127_5057089_8	397945.Aave_2645	2.405e-56	197.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,4AE5T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
ZZS3_k127_5057089_7	543728.Vapar_2332	2.246e-96	318.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,4AAVF@80864|Comamonadaceae	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
ZZS3_k127_5057089_9	614083.AWQR01000005_gene991	4.651e-55	206.0	COG3686@1|root,COG3686@2|Bacteria,1N8EA@1224|Proteobacteria,2VSWW@28216|Betaproteobacteria,4AEFK@80864|Comamonadaceae	28216|Betaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
ZZS3_k127_5057089_3	296591.Bpro_2272	2.09e-175	565.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,4A9W3@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
ZZS3_k127_5057089_5	296591.Bpro_2273	4.027e-139	464.0	COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2VHGX@28216|Betaproteobacteria,4ACTB@80864|Comamonadaceae	28216|Betaproteobacteria	P	SMART AAA ATPase	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
ZZS3_k127_5057089_4	1123504.JQKD01000002_gene3568	3.624e-148	471.0	COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2VI9N@28216|Betaproteobacteria,4AC9H@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ZZS3_k127_5057089_11	1198452.Jab_2c01700	1.98e-39	153.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	YXWGXW
ZZS3_k127_5057089_2	365046.Rta_23240	4.468e-211	685.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,4AB86@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lytic transglycosylase catalytic	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
ZZS3_k127_5057089_6	358220.C380_09385	1.854e-124	404.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,4A9S4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
ZZS3_k127_5057089_10	595537.Varpa_2515	1.006e-42	159.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,4ACT7@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_5075933_6	670292.JH26_17050	2.111e-23	109.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Trans_reg_C
ZZS3_k127_5075933_5	296591.Bpro_4216	4.156e-56	205.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2W2GN@28216|Betaproteobacteria,4AHRN@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5075933_3	365046.Rta_05520	2.421e-92	308.0	COG1670@1|root,COG1670@2|Bacteria,1QVH4@1224|Proteobacteria,2VQSE@28216|Betaproteobacteria,4AAF3@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_5075933_2	365046.Rta_05530	3.827e-149	486.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,4AB1F@80864|Comamonadaceae	28216|Betaproteobacteria	P	CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
ZZS3_k127_5075933_0	365046.Rta_05540	1.076e-212	679.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,4AANK@80864|Comamonadaceae	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
ZZS3_k127_5075933_1	358220.C380_03015	2.428e-187	587.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,4ABB7@80864|Comamonadaceae	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
ZZS3_k127_5075933_4	296591.Bpro_4202	2.973e-59	234.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,4AA8W@80864|Comamonadaceae	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
ZZS3_k127_507675_5	595537.Varpa_3401	8.995e-159	503.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,4AACA@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ZZS3_k127_507675_9	338969.Rfer_1922	8.056e-128	414.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2VM8Y@28216|Betaproteobacteria,4ACFU@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR	ilvR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_507675_7	365046.Rta_16160	2.982e-150	479.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,4AAHS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
ZZS3_k127_507675_10	365046.Rta_16170	4.828e-108	353.0	COG1802@1|root,COG1802@2|Bacteria,1PVIG@1224|Proteobacteria,2VNY3@28216|Betaproteobacteria,4ABDD@80864|Comamonadaceae	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_507675_3	358220.C380_15610	1.423e-197	626.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2VHK0@28216|Betaproteobacteria,4A9P3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Malonyl-CoA decarboxylase	matA	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
ZZS3_k127_507675_6	365046.Rta_16190	4.439e-155	518.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHHP@28216|Betaproteobacteria,4ABEQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_507675_11	296591.Bpro_2093	4.571e-96	323.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,4ACFI@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_507675_2	365046.Rta_16200	6.696e-274	862.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIJX@28216|Betaproteobacteria,4AA7T@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	matB	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_507675_8	983917.RGE_32290	1.96e-144	465.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2VMD3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_507675_1	983917.RGE_32300	4.998e-289	903.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2VIMW@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
ZZS3_k127_507675_15	365046.Rta_00380	5.639e-39	155.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2VMTJ@28216|Betaproteobacteria,4ADKZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4130	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
ZZS3_k127_507675_13	365046.Rta_00380	1.894e-52	192.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2VMTJ@28216|Betaproteobacteria,4ADKZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4130	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
ZZS3_k127_507675_14	1276756.AUEX01000012_gene3591	6.42e-49	195.0	COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2VUY4@28216|Betaproteobacteria,4AE71@80864|Comamonadaceae	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_507675_0	358220.C380_02370	0.0	1255.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,4AAEC@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
ZZS3_k127_507675_4	543728.Vapar_5565	3.852e-182	578.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,4AAG9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
ZZS3_k127_507675_12	1219031.BBJR01000038_gene3131	6.238e-78	264.0	COG1622@1|root,COG2132@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2VK95@28216|Betaproteobacteria,4AGYB@80864|Comamonadaceae	28216|Betaproteobacteria	CQ	Copper binding proteins, plastocyanin/azurin family	nirK	-	1.3.3.5,1.7.2.1	ko:K00368,ko:K08100	ko00860,ko00910,ko01110,ko01120,map00860,map00910,map01110,map01120	M00529	R00783,R00785,R02394	RC00086,RC01983	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrome_CBB3
ZZS3_k127_5078595_15	1223521.BBJX01000008_gene1366	3.218e-28	114.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAP6@80864|Comamonadaceae	28216|Betaproteobacteria	V	Transporter, hydrophobe amphiphile efflux-1 (HAE1) family	acrB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_5078595_3	365046.Rta_13500	5.858e-164	526.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,4AAYK@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_5078595_7	365046.Rta_13490	3.004e-66	233.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,4AE9P@80864|Comamonadaceae	28216|Betaproteobacteria	K	Tetracycline transcriptional repressor MAATS-type	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
ZZS3_k127_5078595_17	296591.Bpro_1153	2.331e-27	117.0	29F9U@1|root,3027G@2|Bacteria,1RFT2@1224|Proteobacteria,2VS6S@28216|Betaproteobacteria,4AE04@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5078595_18	76114.ebA3357	3.048e-09	65.0	29F9U@1|root,3027G@2|Bacteria,1RFT2@1224|Proteobacteria,2VS6S@28216|Betaproteobacteria,2KWEF@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5078595_10	365046.Rta_11660	2.699e-52	192.0	2EC1S@1|root,3360X@2|Bacteria,1N9VV@1224|Proteobacteria,2VX12@28216|Betaproteobacteria,4AFGI@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5078595_6	296591.Bpro_3463	1.307e-93	314.0	COG4101@1|root,COG4101@2|Bacteria,1RB8W@1224|Proteobacteria,2VPF8@28216|Betaproteobacteria,4AD0E@80864|Comamonadaceae	28216|Betaproteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_5078595_4	1502851.FG93_00785	5.308e-148	483.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,3JR32@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	MA20_30655	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
ZZS3_k127_5078595_13	1100720.ALKN01000024_gene1616	8.066e-35	152.0	COG3194@1|root,COG3194@2|Bacteria,1N695@1224|Proteobacteria,2VU7J@28216|Betaproteobacteria,4AJUI@80864|Comamonadaceae	28216|Betaproteobacteria	F	Ureidoglycolate lyase	-	-	4.3.2.3	ko:K01483	ko00230,ko01100,map00230,map01100	-	R00776	RC00153,RC00379	ko00000,ko00001,ko01000	-	-	-	Ureidogly_lyase
ZZS3_k127_5078595_11	1442599.JAAN01000011_gene395	1.333e-50	186.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
ZZS3_k127_5078595_0	1123504.JQKD01000057_gene3213	0.0	1107.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,4A9QR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
ZZS3_k127_5078595_2	1411123.JQNH01000001_gene922	4.551e-167	530.0	COG1638@1|root,COG1638@2|Bacteria,1MXUZ@1224|Proteobacteria,2TTTA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	MA20_17110	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_5078595_9	1205680.CAKO01000039_gene451	4.876e-55	212.0	COG3090@1|root,COG3090@2|Bacteria,1QXYB@1224|Proteobacteria,2TTWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_5078595_1	420324.KI911943_gene5320	1.295e-213	670.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,1JTRM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	TIGRFAM TRAP transporter, DctM subunit	MA20_17100	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_5078595_5	365046.Rta_10410	3.285e-117	386.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF900,Sel1
ZZS3_k127_5078595_12	365046.Rta_27540	1.519e-37	151.0	2BX6S@1|root,324B7@2|Bacteria,1RJA2@1224|Proteobacteria,2VTEW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1439
ZZS3_k127_5078595_8	748247.AZKH_p0462	1.455e-57	203.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2VRM6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS3_k127_5078595_14	748247.AZKH_p0116	1.757e-28	125.0	COG3631@1|root,COG3631@2|Bacteria,1PT2G@1224|Proteobacteria,2WA86@28216|Betaproteobacteria,2KYWR@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
ZZS3_k127_5096523_2	365046.Rta_32070	1.998e-120	387.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,4ABP4@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS3_k127_5096523_4	365046.Rta_32080	3.741e-25	108.0	290H9@1|root,2ZN66@2|Bacteria,1P9N2@1224|Proteobacteria,2W6IV@28216|Betaproteobacteria,4AII0@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5096523_1	365046.Rta_32110	1.503e-120	387.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,4AAK0@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
ZZS3_k127_5096523_0	365046.Rta_32210	1.431e-238	742.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2VJN1@28216|Betaproteobacteria,4AAMZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_5096523_3	365046.Rta_32220	1.816e-100	329.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2VH5W@28216|Betaproteobacteria,4AAKP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Basic membrane lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
ZZS3_k127_510335_3	543728.Vapar_4728	1.199e-84	281.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,4A9QR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
ZZS3_k127_510335_1	365046.Rta_22690	9.748e-145	467.0	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,2VIIF@28216|Betaproteobacteria,4A9UA@80864|Comamonadaceae	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_510335_4	365046.Rta_22680	9.702e-12	70.0	COG2104@1|root,COG2104@2|Bacteria,1PU95@1224|Proteobacteria,2WARC@28216|Betaproteobacteria,4AFWE@80864|Comamonadaceae	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ZZS3_k127_510335_2	365046.Rta_22670	1.276e-139	449.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,4A9ZW@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
ZZS3_k127_510335_0	1265502.KB905940_gene2961	4.725e-161	527.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,2VHWQ@28216|Betaproteobacteria,4A9ZX@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
ZZS3_k127_5118192_15	596154.Alide2_2531	6.673e-30	124.0	COG0095@1|root,COG0095@2|Bacteria,1MYU3@1224|Proteobacteria,2VSY9@28216|Betaproteobacteria,4AJEJ@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	-
ZZS3_k127_5118192_7	296591.Bpro_1200	5.402e-83	286.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2VRH6@28216|Betaproteobacteria,4AE8X@80864|Comamonadaceae	28216|Betaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
ZZS3_k127_5118192_2	296591.Bpro_1194	2.553e-247	783.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,4AB63@80864|Comamonadaceae	28216|Betaproteobacteria	F	thymidine phosphorylase	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
ZZS3_k127_5118192_8	296591.Bpro_1192	9.217e-83	298.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2VQSG@28216|Betaproteobacteria,4AEAD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
ZZS3_k127_5118192_3	1157708.KB907462_gene929	8.163e-189	602.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,4AA4G@80864|Comamonadaceae	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
ZZS3_k127_5118192_6	402626.Rpic_1707	1.038e-100	332.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2VJJ4@28216|Betaproteobacteria,1K3H0@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
ZZS3_k127_5118192_18	296591.Bpro_1175	1.38e-16	82.0	2DVDD@1|root,331C3@2|Bacteria,1N6VD@1224|Proteobacteria,2VVVT@28216|Betaproteobacteria,4AFMG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
ZZS3_k127_5118192_0	395495.Lcho_0148	0.0	1136.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1KKHS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
ZZS3_k127_5118192_14	296591.Bpro_1181	9.128e-31	126.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5118192_12	296591.Bpro_1171	8.995e-35	147.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,4ABA8@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM heat shock protein DnaJ domain protein	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
ZZS3_k127_5118192_4	296591.Bpro_4294	2.54e-112	368.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,4AGD2@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_5118192_10	296591.Bpro_1169	9.7e-45	166.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VVNY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_5118192_11	365044.Pnap_2306	3.305e-42	162.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,4AF2I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_5118192_9	365044.Pnap_2306	1.618e-50	183.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,4AF2I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_5118192_13	75379.Tint_1863	5.741e-34	151.0	2D596@1|root,32TII@2|Bacteria,1N3RK@1224|Proteobacteria,2VVE7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5118192_1	296591.Bpro_5555	3.29e-254	794.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria,4AC3U@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC-1 domain protein	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
ZZS3_k127_5118192_5	1121918.ARWE01000001_gene2709	2.562e-103	344.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,42Q34@68525|delta/epsilon subdivisions,2WN9I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM formate nitrite transporter	fdhC	-	-	ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2	-	-	Form_Nir_trans,Response_reg
ZZS3_k127_5118192_17	1121020.JIAG01000004_gene2122	3.167e-19	89.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
ZZS3_k127_513084_6	365046.Rta_15130	7.472e-162	514.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,4ABU6@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS3_k127_513084_20	1458275.AZ34_11660	6.971e-105	361.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2VIX6@28216|Betaproteobacteria,4ABDH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
ZZS3_k127_513084_10	365046.Rta_15100	9.016e-128	415.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHUJ@28216|Betaproteobacteria,4ACJ5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
ZZS3_k127_513084_25	296591.Bpro_2899	5.555e-83	281.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VK49@28216|Betaproteobacteria,4ABT7@80864|Comamonadaceae	28216|Betaproteobacteria	S	flavodoxin nitric oxide synthase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_5
ZZS3_k127_513084_33	595537.Varpa_3545	1.262e-46	172.0	COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,2VSDZ@28216|Betaproteobacteria,4AEIQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM DoxX family protein	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
ZZS3_k127_513084_15	595537.Varpa_3546	9.163e-121	391.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,4AC8J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
ZZS3_k127_513084_14	365046.Rta_15060	6.743e-121	395.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,2VJTZ@28216|Betaproteobacteria,4A9RY@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	allS_2	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_513084_12	987059.RBXJA2T_05493	1.43e-123	404.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,1KK53@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
ZZS3_k127_513084_16	365046.Rta_15030	7.445e-118	385.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,4AAS2@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
ZZS3_k127_513084_8	296591.Bpro_0789	3.828e-138	453.0	COG0683@1|root,COG0683@2|Bacteria,1R8QN@1224|Proteobacteria,2VI0F@28216|Betaproteobacteria,4ADC9@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_513084_0	365046.Rta_15010	0.0	1498.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,4AAP4@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ZZS3_k127_513084_19	543728.Vapar_1995	2.222e-106	363.0	COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,1MW1W@1224|Proteobacteria,2VQSF@28216|Betaproteobacteria,4AGS6@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_513084_36	595537.Varpa_3012	6.453e-33	134.0	COG3474@1|root,COG3474@2|Bacteria,1N7IW@1224|Proteobacteria,2W3Q5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_513084_27	339670.Bamb_6572	4.996e-75	269.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VQ5E@28216|Betaproteobacteria,1K00I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
ZZS3_k127_513084_1	1504672.669784457	0.0	1182.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VM0G@28216|Betaproteobacteria,4ABUI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298,ko:K15408	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
ZZS3_k127_513084_4	1268622.AVS7_00407	1.695e-227	711.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VKWZ@28216|Betaproteobacteria,4A9WX@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
ZZS3_k127_513084_3	887062.HGR_04968	5.037e-281	875.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,4A9Q8@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_513084_22	365046.Rta_15000	2.891e-104	346.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2WFQP@28216|Betaproteobacteria,4ABHJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
ZZS3_k127_513084_11	1089551.KE386572_gene2365	5.106e-125	431.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U0I3@28211|Alphaproteobacteria,4BRC2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_9,Response_reg,dCache_1
ZZS3_k127_513084_31	365046.Rta_38070	6.004e-47	170.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
ZZS3_k127_513084_34	365046.Rta_04710	6.925e-43	158.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,4AEXW@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS3_k127_513084_30	395495.Lcho_4312	7.895e-53	190.0	29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria,1KM7K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
ZZS3_k127_513084_35	1408164.MOLA814_00007	1.977e-41	158.0	COG5605@1|root,COG5605@2|Bacteria,1RH8B@1224|Proteobacteria,2VT9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	oxidase (Subunit iv)	coxQ	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
ZZS3_k127_513084_17	1082933.MEA186_19462	6.941e-115	376.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2U0NA@28211|Alphaproteobacteria,43J9V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
ZZS3_k127_513084_29	189753.AXAS01000016_gene1404	1.715e-65	232.0	COG1845@1|root,COG1845@2|Bacteria,1MXAB@1224|Proteobacteria,2TRFQ@28211|Alphaproteobacteria,3JTBK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c oxidase subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
ZZS3_k127_513084_2	1408164.MOLA814_00004	3.39e-313	968.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VMNB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
ZZS3_k127_513084_5	1408164.MOLA814_00003	1.889e-197	628.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,2VIDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c oxidase (Subunit II)	coxM	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
ZZS3_k127_513084_37	365046.Rta_18120	8.391e-31	126.0	2E1BI@1|root,32WRE@2|Bacteria,1N0CK@1224|Proteobacteria,2VURG@28216|Betaproteobacteria,4AEX5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_513084_18	948106.AWZT01000015_gene758	6.051e-113	373.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,1K2JD@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
ZZS3_k127_513084_21	323848.Nmul_A1582	1.225e-104	349.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2WGMS@28216|Betaproteobacteria,3721D@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
ZZS3_k127_513084_32	1254432.SCE1572_39360	7.11e-47	171.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,43827@68525|delta/epsilon subdivisions,2X3CD@28221|Deltaproteobacteria,2YVE1@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_513084_38	448385.sce0758	9.754e-22	100.0	COG2169@1|root,COG2169@2|Bacteria,1NICQ@1224|Proteobacteria,43EDD@68525|delta/epsilon subdivisions,2X81D@28221|Deltaproteobacteria,2Z3J7@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS3_k127_513084_9	365046.Rta_06100	1.717e-134	440.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,2VK3C@28216|Betaproteobacteria,4AC81@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_513084_28	365046.Rta_06090	2.794e-74	252.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,2VRYY@28216|Betaproteobacteria,4ADX2@80864|Comamonadaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
ZZS3_k127_513084_13	296591.Bpro_0644	3.072e-121	395.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VJHN@28216|Betaproteobacteria,4AJ35@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_513084_26	296591.Bpro_0645	3.228e-82	282.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,2VQER@28216|Betaproteobacteria,4AEJB@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Glutathione S-transferase domain	gst7	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
ZZS3_k127_513084_23	1000565.METUNv1_01053	1.605e-89	315.0	COG3576@1|root,COG3576@2|Bacteria,1QTUS@1224|Proteobacteria,2VNJ5@28216|Betaproteobacteria,2KXUR@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
ZZS3_k127_513084_24	296591.Bpro_4176	2.059e-86	297.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VPAA@28216|Betaproteobacteria,4ADWT@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Glutathione S-transferase domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
ZZS3_k127_513084_7	296591.Bpro_4178	5.127e-144	461.0	COG0583@1|root,COG0583@2|Bacteria,1MWM1@1224|Proteobacteria,2VMC2@28216|Betaproteobacteria,4AJ8Q@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5136549_0	365046.Rta_13380	0.0	1455.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,4ACHC@80864|Comamonadaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS3_k127_5136549_7	365046.Rta_13390	2.303e-108	388.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VHV8@28216|Betaproteobacteria,4AAEZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	coxM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
ZZS3_k127_5136549_5	365046.Rta_13400	1.252e-153	491.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VIJR@28216|Betaproteobacteria,4A9TN@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
ZZS3_k127_5136549_4	1458275.AZ34_08095	2.636e-172	552.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2VNH5@28216|Betaproteobacteria,4ACDG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
ZZS3_k127_5136549_9	296591.Bpro_0573	2.068e-69	258.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2VREK@28216|Betaproteobacteria,4ADYM@80864|Comamonadaceae	28216|Betaproteobacteria	S	carbon monoxide dehydrogenase subunit G	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
ZZS3_k127_5136549_8	391735.Veis_4978	4.315e-106	361.0	COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,2VK6Q@28216|Betaproteobacteria,4AH4M@80864|Comamonadaceae	28216|Betaproteobacteria	E	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_5136549_1	365046.Rta_13430	4.279e-315	989.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,4ABJM@80864|Comamonadaceae	28216|Betaproteobacteria	P	TonB-dependent receptor plug	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
ZZS3_k127_5136549_3	296591.Bpro_0572	1.497e-184	582.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,4AB9E@80864|Comamonadaceae	28216|Betaproteobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	coxI	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
ZZS3_k127_5136549_2	1157708.KB907471_gene184	8.522e-203	642.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9YR@80864|Comamonadaceae	28216|Betaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	dctD	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K10126,ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	M00504	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_5136549_6	1157708.KB907471_gene183	1.201e-151	490.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VIMC@28216|Betaproteobacteria,4ABAX@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gltS2	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
ZZS3_k127_5139759_5	1121116.KB894774_gene1779	4.288e-06	58.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,4ABCD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
ZZS3_k127_5139759_3	1123504.JQKD01000004_gene5151	1.225e-103	345.0	COG1028@1|root,COG1028@2|Bacteria,1R6D6@1224|Proteobacteria,2VQUW@28216|Betaproteobacteria,4AHJZ@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_5139759_1	266265.Bxe_C0851	5.365e-224	704.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,1K5DH@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_5139759_0	596153.Alide_2404	2.354e-232	721.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VMYJ@28216|Betaproteobacteria,4AGZW@80864|Comamonadaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_5139759_2	1276756.AUEX01000029_gene2200	1.117e-122	401.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5139759_4	543728.Vapar_5774	4.468e-84	286.0	COG1024@1|root,COG1024@2|Bacteria,1P5FE@1224|Proteobacteria,2VIQE@28216|Betaproteobacteria,4ABJ5@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS3_k127_5143816_1	296591.Bpro_3207	7.727e-141	457.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1MVGQ@1224|Proteobacteria,2VHF5@28216|Betaproteobacteria,4AAX3@80864|Comamonadaceae	28216|Betaproteobacteria	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
ZZS3_k127_5143816_2	338969.Rfer_1901	2.945e-131	423.0	COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,2VID6@28216|Betaproteobacteria,4AA8T@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM ABC transporter related	rbsA	-	-	ko:K10554	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	ABC_tran
ZZS3_k127_5143816_0	296591.Bpro_3204	4.065e-145	467.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VJ3R@28216|Betaproteobacteria,4ABTD@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10553	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	BPD_transp_2
ZZS3_k127_5143816_3	296591.Bpro_3203	1.301e-93	308.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VJFU@28216|Betaproteobacteria,4ABQG@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
ZZS3_k127_5157310_15	1504672.669786746	5.195e-85	283.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,4A9W7@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_5157310_7	887062.HGR_04308	5.586e-131	429.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,4AAN8@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
ZZS3_k127_5157310_14	365046.Rta_24420	3.19e-97	337.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
ZZS3_k127_5157310_12	543728.Vapar_1799	2.021e-102	341.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,4A9WP@80864|Comamonadaceae	28216|Betaproteobacteria	DM	peptidase	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
ZZS3_k127_5157310_5	365046.Rta_24400	4.178e-147	472.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,4ACQR@80864|Comamonadaceae	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_5157310_6	365046.Rta_24390	1.825e-145	464.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,4AGY1@80864|Comamonadaceae	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
ZZS3_k127_5157310_2	365046.Rta_24370	1.16e-249	775.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,4A9RZ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
ZZS3_k127_5157310_13	338969.Rfer_2776	1.143e-101	336.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,4AA9M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the BI1 family	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
ZZS3_k127_5157310_18	365046.Rta_24350	1.807e-65	227.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2VRBU@28216|Betaproteobacteria,4AE3V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Haem-degrading	glcG	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
ZZS3_k127_5157310_21	365046.Rta_24340	8.372e-09	64.0	COG4256@1|root,COG4256@2|Bacteria,1NGJH@1224|Proteobacteria,2VY5P@28216|Betaproteobacteria,4AFUY@80864|Comamonadaceae	28216|Betaproteobacteria	P	Hemin uptake protein	-	-	-	-	-	-	-	-	-	-	-	-	hemP
ZZS3_k127_5157310_19	365046.Rta_24330	1.398e-60	223.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSVW@28216|Betaproteobacteria,4ADW4@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS3_k127_5157310_9	365046.Rta_24320	3.558e-123	397.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria,4ABX8@80864|Comamonadaceae	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	exbB1	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
ZZS3_k127_5157310_17	365046.Rta_24310	1.272e-65	231.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,4AD9Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
ZZS3_k127_5157310_20	398578.Daci_4621	1.313e-31	126.0	COG2906@1|root,COG2906@2|Bacteria,1MZZM@1224|Proteobacteria,2VUH9@28216|Betaproteobacteria,4AF0S@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM BFD domain protein 2Fe-2S -binding domain protein	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
ZZS3_k127_5157310_8	365046.Rta_24240	1.935e-127	428.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VH77@28216|Betaproteobacteria,4ACGQ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	-	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
ZZS3_k127_5157310_10	365046.Rta_24230	2.182e-110	360.0	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2VJHT@28216|Betaproteobacteria,4ACJF@80864|Comamonadaceae	28216|Betaproteobacteria	C	PKHD-type hydroxylase	ybiX	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
ZZS3_k127_5157310_0	365046.Rta_24220	0.0	1151.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2VIQR@28216|Betaproteobacteria,4AB9T@80864|Comamonadaceae	28216|Betaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
ZZS3_k127_5157310_16	365046.Rta_24210	1.414e-74	277.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2VPZP@28216|Betaproteobacteria,4AA91@80864|Comamonadaceae	28216|Betaproteobacteria	P	Iron-storage protein	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
ZZS3_k127_5157310_1	365046.Rta_24200	7.751e-283	877.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,4A9PC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
ZZS3_k127_5157310_11	296591.Bpro_3044	6.24e-107	347.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,2VI7T@28216|Betaproteobacteria,4A9TG@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
ZZS3_k127_5157310_4	365046.Rta_24180	2.757e-159	504.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,4ABUX@80864|Comamonadaceae	28216|Betaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
ZZS3_k127_5157310_3	365046.Rta_24170	8.318e-200	627.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,4AA18@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS3_k127_5183762_3	365046.Rta_10500	4.888e-40	151.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VKC1@28216|Betaproteobacteria,4ABYH@80864|Comamonadaceae	28216|Betaproteobacteria	C	e3 binding domain	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_5183762_2	365046.Rta_10490	3.051e-202	654.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,4ACZ7@80864|Comamonadaceae	28216|Betaproteobacteria	C	Transketolase, C-terminal domain	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
ZZS3_k127_5183762_1	365046.Rta_10480	3.186e-242	753.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,4AC1K@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Dehydrogenase, E1 component	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
ZZS3_k127_5183762_0	543728.Vapar_2048	3.73e-299	932.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,4AAYC@80864|Comamonadaceae	28216|Betaproteobacteria	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_5216159_7	365046.Rta_17440	3.242e-49	176.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,4AA10@80864|Comamonadaceae	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
ZZS3_k127_5216159_2	1276756.AUEX01000019_gene3461	2.493e-131	428.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,4AAQS@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ZZS3_k127_5216159_5	365046.Rta_17460	8.553e-96	316.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,4ABF3@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
ZZS3_k127_5216159_3	365046.Rta_17470	2.704e-126	408.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,4ABH9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
ZZS3_k127_5216159_4	365046.Rta_17480	3.148e-120	395.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,4AAB8@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
ZZS3_k127_5216159_1	365046.Rta_17490	9.691e-197	634.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,4A9T1@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
ZZS3_k127_5216159_0	365046.Rta_17500	1.997e-219	690.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,4AC8F@80864|Comamonadaceae	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
ZZS3_k127_5216159_6	365046.Rta_17510	5.845e-60	209.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,4AC0C@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
ZZS3_k127_5228789_8	1157708.KB907451_gene4752	3.999e-13	70.0	2DSCP@1|root,33FJE@2|Bacteria,1NMGV@1224|Proteobacteria,2VYBI@28216|Betaproteobacteria,4AG27@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5228789_5	1268622.AVS7_00939	2.268e-128	413.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,4A9ZR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
ZZS3_k127_5228789_3	365046.Rta_37890	2.545e-182	584.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,4AAUW@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
ZZS3_k127_5228789_0	365046.Rta_37900	0.0	1045.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,4A9K5@80864|Comamonadaceae	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
ZZS3_k127_5228789_2	365046.Rta_37910	1.084e-183	579.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,4AC60@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
ZZS3_k127_5228789_6	1123504.JQKD01000006_gene1575	2.162e-89	305.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,4ABUM@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
ZZS3_k127_5228789_4	365046.Rta_37930	5.911e-173	563.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,4AB3E@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS3_k127_5228789_7	656024.FsymDg_2592	1.297e-29	128.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,4EUFQ@85013|Frankiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ZZS3_k127_5228789_1	365046.Rta_37940	1.078e-233	724.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VIT5@28216|Betaproteobacteria,4A9TV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_5237352_4	398578.Daci_3265	6.927e-116	376.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,4ABX2@80864|Comamonadaceae	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS3_k127_5237352_2	1157708.KB907450_gene5942	7.246e-128	429.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1N96D@1224|Proteobacteria,2WEEK@28216|Betaproteobacteria,4AJR1@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_5237352_5	543728.Vapar_2803	1.959e-48	191.0	COG2201@1|root,COG2201@2|Bacteria,1RCWE@1224|Proteobacteria,2VSBP@28216|Betaproteobacteria,4AEET@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PFAM CheB methylesterase	cheB1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
ZZS3_k127_5237352_3	686578.AFFX01000006_gene3325	2.16e-120	411.0	COG1352@1|root,COG1352@2|Bacteria,1NQTI@1224|Proteobacteria,1RS9Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	COG1352 Methylase of chemotaxis methyl-accepting proteins	cheR3	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
ZZS3_k127_5237352_0	1388763.O165_012200	5.726e-185	586.0	COG0745@1|root,COG2199@1|root,COG4251@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,1T2D4@1236|Gammaproteobacteria,1YVXM@136845|Pseudomonas putida group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF,HATPase_c,HisKA,Response_reg
ZZS3_k127_5237352_1	205922.Pfl01_2646	3.861e-144	466.0	COG0745@1|root,COG2199@1|root,COG4251@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,1T2D4@1236|Gammaproteobacteria,1YPNE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	sensor histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF,HATPase_c,HisKA,Response_reg
ZZS3_k127_525454_14	265072.Mfla_1883	0.0006343	43.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,2VIUK@28216|Betaproteobacteria,2KNPC@206350|Nitrosomonadales	206350|Nitrosomonadales	CP	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
ZZS3_k127_525454_2	1297570.MESS4_20034	1.653e-167	559.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2U0E0@28211|Alphaproteobacteria,43MUG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_525454_1	595537.Varpa_5097	6.668e-180	568.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,4ACE5@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
ZZS3_k127_525454_12	264198.Reut_B4138	1.209e-42	159.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05527,ko:K09780	-	-	-	-	ko00000,ko03000	-	-	-	YCII
ZZS3_k127_525454_5	264198.Reut_B4136	2.756e-139	466.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VMND@28216|Betaproteobacteria,1K120@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS3_k127_525454_6	1131814.JAFO01000001_gene4142	1.125e-128	434.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U0D6@28211|Alphaproteobacteria,3EZRM@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	MA20_14315	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
ZZS3_k127_525454_7	264198.Reut_B4134	2.004e-111	368.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VH0P@28216|Betaproteobacteria,1K3IZ@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
ZZS3_k127_525454_0	264198.Reut_B4133	1.175e-218	695.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VHRA@28216|Betaproteobacteria,1JZXK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
ZZS3_k127_525454_11	264198.Reut_B4130	3.069e-96	323.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2VZHH@28216|Betaproteobacteria,1KFT6@119060|Burkholderiaceae	28216|Betaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_525454_9	595537.Varpa_3957	3.488e-105	351.0	COG3181@1|root,COG3181@2|Bacteria,1N4MC@1224|Proteobacteria,2VKJS@28216|Betaproteobacteria,4ABJ4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_525454_10	1380394.JADL01000002_gene1393	2.129e-96	325.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U2X9@28211|Alphaproteobacteria,2JTJW@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_525454_3	358220.C380_19325	2.391e-150	481.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_525454_8	358220.C380_19330	9.745e-111	362.0	COG1028@1|root,COG1028@2|Bacteria,1R3ZC@1224|Proteobacteria,2VMWV@28216|Betaproteobacteria,4ABNX@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_525454_13	1157708.KB907472_gene1276	0.0001209	45.0	COG1529@1|root,COG2010@1|root,COG1529@2|Bacteria,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2WHBT@28216|Betaproteobacteria,4AATP@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.2.1	ko:K18030	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C2,Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_525454_4	1157708.KB907457_gene2597	8.955e-144	458.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,4A9IZ@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_525911_6	398578.Daci_4976	1.975e-65	225.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,4A9UC@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
ZZS3_k127_525911_8	1268622.AVS7_03583	4.842e-56	206.0	COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria,2VRI7@28216|Betaproteobacteria,4ADWU@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_525911_2	365046.Rta_13540	3.05e-232	724.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VJME@28216|Betaproteobacteria,4AAMJ@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	siaT_7	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_525911_7	987059.RBXJA2T_00799	1.839e-63	228.0	COG1073@1|root,COG1073@2|Bacteria,1R67P@1224|Proteobacteria,2VQQP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
ZZS3_k127_525911_5	296591.Bpro_1771	1.847e-73	255.0	COG1794@1|root,COG1794@2|Bacteria,1MW3C@1224|Proteobacteria,2VSWN@28216|Betaproteobacteria,4AF9H@80864|Comamonadaceae	28216|Betaproteobacteria	M	racemase activity, acting on amino acids and derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_525911_3	365046.Rta_13480	1.191e-169	542.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,2VIQ9@28216|Betaproteobacteria,4AA41@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_525911_0	1157708.KB907471_gene181	1.885e-267	843.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,2VN7Y@28216|Betaproteobacteria,4AD8T@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_525911_1	1123504.JQKD01000085_gene41	6.533e-265	844.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,2VN7Y@28216|Betaproteobacteria,4AD8T@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_525911_4	1366050.N234_00780	6.316e-158	503.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VZQB@28216|Betaproteobacteria,1KH2X@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_525911_9	1157708.KB907471_gene183	2.219e-54	196.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VIMC@28216|Betaproteobacteria,4ABAX@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gltS2	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
ZZS3_k127_5272917_2	365046.Rta_11910	7.967e-213	687.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2VMQJ@28216|Betaproteobacteria,4AEJ5@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.156,4.2.1.42	ko:K20023	ko00053,map00053	-	R05608	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_5272917_5	365046.Rta_11830	4.218e-155	503.0	COG0702@1|root,COG0702@2|Bacteria,1MZ0C@1224|Proteobacteria,2VNMR@28216|Betaproteobacteria,4AJB8@80864|Comamonadaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,Epimerase,NAD_binding_10
ZZS3_k127_5272917_12	365046.Rta_11820	3.156e-50	183.0	2DPIK@1|root,32UM7@2|Bacteria,1MZQR@1224|Proteobacteria,2VUE4@28216|Betaproteobacteria,4AEXA@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5272917_4	595537.Varpa_2783	1.015e-155	528.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,4ACW0@80864|Comamonadaceae	28216|Betaproteobacteria	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_7,Response_reg
ZZS3_k127_5272917_3	1449049.JONW01000005_gene867	7.252e-204	647.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,2KH40@204458|Caulobacterales	204458|Caulobacterales	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
ZZS3_k127_5272917_0	365046.Rta_11790	4.253e-313	979.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIA6@28216|Betaproteobacteria,4A9U6@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_5272917_15	543728.Vapar_1688	6.484e-42	171.0	COG3805@1|root,COG3805@2|Bacteria,1N2DN@1224|Proteobacteria,2WFGC@28216|Betaproteobacteria,4AFQF@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Dopa 4,5-dioxygenase family	-	-	-	ko:K10253	-	-	-	-	ko00000,ko01000	-	-	-	DOPA_dioxygen
ZZS3_k127_5272917_8	338969.Rfer_1116	5.989e-103	350.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS3_k127_5272917_7	395494.Galf_0934	6.507e-132	429.0	COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,2VHAD@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	metabolite transporter	cnrT	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_5272917_9	365046.Rta_11750	1.881e-76	274.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2VQ08@28216|Betaproteobacteria,4ADUA@80864|Comamonadaceae	28216|Betaproteobacteria	P	Cation efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
ZZS3_k127_5272917_18	365046.Rta_11740	4.278e-21	98.0	COG4575@1|root,COG4575@2|Bacteria	2|Bacteria	T	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
ZZS3_k127_5272917_20	595537.Varpa_4243	0.0002447	49.0	2EIPU@1|root,33DDH@2|Bacteria,1NKK4@1224|Proteobacteria,2VYJM@28216|Betaproteobacteria,4AFZ7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5272917_6	1157708.KB907453_gene4355	1.773e-147	480.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2VIIW@28216|Betaproteobacteria,4AAW2@80864|Comamonadaceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS3_k127_5272917_1	62928.azo2950	2.594e-247	798.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VM67@28216|Betaproteobacteria,2KVR6@206389|Rhodocyclales	206389|Rhodocyclales	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_5272917_14	296591.Bpro_3486	4.437e-43	164.0	COG3678@1|root,COG3678@2|Bacteria,1MZKK@1224|Proteobacteria,2W3Z1@28216|Betaproteobacteria,4AIAU@80864|Comamonadaceae	28216|Betaproteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
ZZS3_k127_5272917_11	420662.Mpe_A1635	3.945e-53	201.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSDP@28216|Betaproteobacteria,1KPBC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
ZZS3_k127_5272917_10	1276756.AUEX01000021_gene3352	3.114e-66	229.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2VSDN@28216|Betaproteobacteria,4ADQQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
ZZS3_k127_5272917_17	1286631.X805_15530	9.116e-23	101.0	COG5569@1|root,COG5569@2|Bacteria,1N8CJ@1224|Proteobacteria,2VVSU@28216|Betaproteobacteria,1KMMC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	cusF	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
ZZS3_k127_5272917_13	365046.Rta_06430	1.813e-45	167.0	COG1145@1|root,32SB1@2|Bacteria,1N096@1224|Proteobacteria,2VVRP@28216|Betaproteobacteria,4AFS7@80864|Comamonadaceae	28216|Betaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
ZZS3_k127_5272917_16	420662.Mpe_A1626	1.287e-36	145.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,1KIT0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
ZZS3_k127_5280918_0	365046.Rta_15130	0.0	1165.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,4ABU6@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS3_k127_5280918_12	365046.Rta_19250	2.78e-31	128.0	COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,2VWM8@28216|Betaproteobacteria,4AEZW@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_5280918_1	365046.Rta_19240	3.207e-209	677.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VK72@28216|Betaproteobacteria,4A9RW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
ZZS3_k127_5280918_4	1265502.KB905945_gene653	3.346e-158	511.0	COG0607@1|root,COG3221@1|root,COG0607@2|Bacteria,COG3221@2|Bacteria,1RKRX@1224|Proteobacteria,2VTV2@28216|Betaproteobacteria,4AF5T@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd,Rhodanese
ZZS3_k127_5280918_13	876269.ARWA01000001_gene1100	3.271e-29	127.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2VCP5@28211|Alphaproteobacteria,3NCPU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
ZZS3_k127_5280918_9	232721.Ajs_2773	1.552e-68	243.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria,4ABB2@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Tol-Pal system TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
ZZS3_k127_5280918_10	614083.AWQR01000019_gene3786	2.106e-51	188.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,4AEG5@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
ZZS3_k127_5280918_5	365046.Rta_15160	3.074e-120	392.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,4AAWM@80864|Comamonadaceae	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
ZZS3_k127_5280918_11	365046.Rta_15170	2.47e-51	202.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,4AEEQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM thioesterase superfamily protein	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
ZZS3_k127_5280918_2	535289.Dtpsy_2259	3.351e-209	670.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,4AAIV@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase, class I and II	aspC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
ZZS3_k127_5280918_6	365046.Rta_15190	1.151e-76	267.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,4ACUC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
ZZS3_k127_5280918_8	1276756.AUEX01000010_gene1650	2.168e-74	254.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,4AE39@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
ZZS3_k127_5280918_3	365046.Rta_15210	8.065e-195	621.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,4A9S0@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
ZZS3_k127_5280918_7	365046.Rta_15220	1.574e-76	259.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,4AA7Q@80864|Comamonadaceae	28216|Betaproteobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
ZZS3_k127_5296327_9	1123255.JHYS01000002_gene2429	4.451e-37	143.0	COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2VRF6@28216|Betaproteobacteria,4ABZC@80864|Comamonadaceae	28216|Betaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
ZZS3_k127_5296327_1	543728.Vapar_4248	4.155e-122	393.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VH2U@28216|Betaproteobacteria,4AA6F@80864|Comamonadaceae	28216|Betaproteobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
ZZS3_k127_5296327_7	595537.Varpa_4273	3.307e-96	337.0	COG0642@1|root,COG2205@2|Bacteria,1QWE1@1224|Proteobacteria	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS,PAS_9
ZZS3_k127_5296327_2	398527.Bphyt_5295	6.741e-118	387.0	COG2267@1|root,COG2267@2|Bacteria,1QUYW@1224|Proteobacteria,2VQ1B@28216|Betaproteobacteria,1K3TZ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_5296327_5	338969.Rfer_3112	4.6e-104	347.0	COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2VIYW@28216|Betaproteobacteria,4AD6Z@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gstP	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3
ZZS3_k127_5296327_10	1500894.JQNN01000001_gene528	1.199e-24	119.0	COG0671@1|root,COG0671@2|Bacteria,1PEF1@1224|Proteobacteria,2WAMH@28216|Betaproteobacteria,477R1@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
ZZS3_k127_5296327_4	365046.Rta_22700	2.204e-109	370.0	COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,2VIYD@28216|Betaproteobacteria,4AA8V@80864|Comamonadaceae	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
ZZS3_k127_5296327_3	1156919.QWC_26288	1.297e-114	387.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,3T55Q@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_5296327_0	365046.Rta_22720	3.927e-150	481.0	COG0715@1|root,COG0715@2|Bacteria,1QQW8@1224|Proteobacteria,2VK0P@28216|Betaproteobacteria,4ACP8@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
ZZS3_k127_5296327_6	365046.Rta_22730	7.148e-99	340.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2VPSG@28216|Betaproteobacteria,4AAXK@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ZZS3_k127_5296327_8	688245.CtCNB1_2065	1.259e-91	307.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2VM4N@28216|Betaproteobacteria,4ABVK@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC transporter	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
ZZS3_k127_5302650_2	395495.Lcho_1252	1.085e-88	298.0	COG2227@1|root,COG2227@2|Bacteria,1QVH1@1224|Proteobacteria,2VRX7@28216|Betaproteobacteria,1KKJH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS3_k127_5302650_3	365046.Rta_26530	1.112e-44	166.0	COG0071@1|root,COG0071@2|Bacteria,1N535@1224|Proteobacteria,2VVND@28216|Betaproteobacteria,4AF0D@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
ZZS3_k127_5302650_0	365046.Rta_26520	6.222e-222	695.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2VI1S@28216|Betaproteobacteria,4AAZP@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_5302650_1	1276756.AUEX01000014_gene2947	4.543e-195	637.0	COG0436@1|root,COG0436@2|Bacteria,1MX6F@1224|Proteobacteria,2VJI9@28216|Betaproteobacteria,4AAZC@80864|Comamonadaceae	28216|Betaproteobacteria	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
ZZS3_k127_5302650_4	365046.Rta_26480	6.769e-14	73.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,4AEI9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
ZZS3_k127_530961_12	365046.Rta_35920	2.659e-34	136.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,4AEBK@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
ZZS3_k127_530961_5	365046.Rta_35910	1.085e-126	408.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,4AAUM@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ZZS3_k127_530961_0	365046.Rta_35880	0.0	1057.0	COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2VGZA@28216|Betaproteobacteria,4ACF2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Serves to protect cells from the toxic effects of hydrogen peroxide	katE	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel,DJ-1_PfpI
ZZS3_k127_530961_10	1268622.AVS7_01639	1.629e-88	302.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,4AB3X@80864|Comamonadaceae	28216|Betaproteobacteria	G	HAD-superfamily hydrolase, subfamily IA, variant 1	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_530961_11	358220.C380_22095	8.232e-79	267.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,4ADKC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
ZZS3_k127_530961_1	365046.Rta_35840	1.895e-296	921.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,4A9Q6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
ZZS3_k127_530961_8	887062.HGR_05071	4.591e-100	351.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,4A9SQ@80864|Comamonadaceae	28216|Betaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS3_k127_530961_3	365046.Rta_35820	5.637e-180	576.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VIVJ@28216|Betaproteobacteria,4ABMK@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
ZZS3_k127_530961_9	296591.Bpro_4453	1.571e-95	317.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VNUR@28216|Betaproteobacteria,4ACZC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Lysine exporter protein (Lyse ygga)	leuE_1	-	-	ko:K11250	-	-	-	-	ko00000,ko02000	2.A.76.1.5	-	-	LysE
ZZS3_k127_530961_2	296591.Bpro_4452	3.463e-189	594.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,4AAY4@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
ZZS3_k127_530961_6	365046.Rta_35790	9.256e-123	425.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,4ABED@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
ZZS3_k127_530961_7	365046.Rta_35780	1.56e-101	344.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2VHN3@28216|Betaproteobacteria,4AB3Q@80864|Comamonadaceae	28216|Betaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS3_k127_530961_4	365046.Rta_35770	4.189e-129	423.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2VH3I@28216|Betaproteobacteria,4AA4W@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS3_k127_530961_16	935837.JAEK01000090_gene445	8.456e-05	46.0	29S70@1|root,30DBH@2|Bacteria,1UB40@1239|Firmicutes,4IMGK@91061|Bacilli,1ZK45@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_530961_13	1159870.KB907785_gene1	4.814e-18	85.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,3T1VV@506|Alcaligenaceae	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
ZZS3_k127_5324832_0	420662.Mpe_A2845	1.375e-264	818.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,1KJSQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
ZZS3_k127_5324832_1	365046.Rta_25780	5.638e-203	640.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,4AAY2@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
ZZS3_k127_5324832_3	1268622.AVS7_00539	2.443e-83	277.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,4ADGK@80864|Comamonadaceae	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
ZZS3_k127_5324832_5	365046.Rta_25760	1.045e-43	166.0	COG3134@1|root,COG3134@2|Bacteria,1R3N3@1224|Proteobacteria,2WIIN@28216|Betaproteobacteria,4AK5S@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
ZZS3_k127_5324832_4	365046.Rta_25750	4.303e-76	264.0	COG1047@1|root,COG1047@2|Bacteria,1QVQJ@1224|Proteobacteria,2VQ5P@28216|Betaproteobacteria,4ADFJ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Peptidylprolyl isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
ZZS3_k127_5324832_2	365046.Rta_25740	3.388e-150	484.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,4AAFR@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART transcription factor jumonji jmjC	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
ZZS3_k127_5362232_6	264198.Reut_B4423	9.363e-48	175.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2VNNN@28216|Betaproteobacteria,1K24Z@119060|Burkholderiaceae	28216|Betaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
ZZS3_k127_5362232_0	365046.Rta_29560	1.167e-184	592.0	COG0693@1|root,COG0693@2|Bacteria,1QJCZ@1224|Proteobacteria,2VJC4@28216|Betaproteobacteria,4ADEP@80864|Comamonadaceae	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
ZZS3_k127_5362232_1	365046.Rta_29540	5.601e-145	466.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2VN9M@28216|Betaproteobacteria,4ADCH@80864|Comamonadaceae	28216|Betaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
ZZS3_k127_5362232_4	1286631.X805_03510	5.521e-79	280.0	COG3181@1|root,COG3181@2|Bacteria,1MYJX@1224|Proteobacteria,2VKS4@28216|Betaproteobacteria,1KN7X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5362232_2	1192759.AKIB01000052_gene922	2.417e-112	371.0	COG2358@1|root,COG2358@2|Bacteria	2|Bacteria	G	TRAP transporter, solute receptor (TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
ZZS3_k127_5362232_5	596154.Alide2_3941	8.16e-65	235.0	COG0066@1|root,COG0066@2|Bacteria,1NZAW@1224|Proteobacteria,2VRJ2@28216|Betaproteobacteria,4ADY1@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
ZZS3_k127_5362232_3	1123060.JONP01000055_gene3805	9.105e-88	293.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TVD2@28211|Alphaproteobacteria,2JV9U@204441|Rhodospirillales	204441|Rhodospirillales	E	Aconitase family (aconitate hydratase)	-	-	-	-	-	-	-	-	-	-	-	-	Aconitase
ZZS3_k127_5362839_6	1100720.ALKN01000033_gene664	1.148e-120	392.0	COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria,2VP7N@28216|Betaproteobacteria,4A9JF@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.1.2.41,4.2.1.101	ko:K18383	ko00360,ko01100,ko01110,map00360,map01100,map01110	-	R05772,R05773	RC00307,RC01468,RC01828	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS3_k127_5362839_1	358220.C380_02830	1.27e-260	812.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
ZZS3_k127_5362839_7	296591.Bpro_0629	2.662e-102	339.0	28ME7@1|root,2ZARX@2|Bacteria,1R90X@1224|Proteobacteria,2VNB6@28216|Betaproteobacteria,4AA7V@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_5362839_2	296591.Bpro_0630	1.148e-184	595.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria,2VKHH@28216|Betaproteobacteria,4ACU3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Pfam:Pyridox_oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
ZZS3_k127_5362839_8	296591.Bpro_0631	3.051e-49	192.0	COG3576@1|root,COG3576@2|Bacteria,1N8Z5@1224|Proteobacteria,2VVVW@28216|Betaproteobacteria,4AEMH@80864|Comamonadaceae	28216|Betaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5362839_5	1100721.ALKO01000017_gene1605	8.33e-134	450.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,4AA20@80864|Comamonadaceae	28216|Betaproteobacteria	V	Transport permease protein	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
ZZS3_k127_5362839_3	543728.Vapar_4964	1.389e-165	526.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,4ABWS@80864|Comamonadaceae	28216|Betaproteobacteria	V	Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
ZZS3_k127_5362839_4	365046.Rta_34630	1.609e-147	474.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2VJCQ@28216|Betaproteobacteria,4AB5Q@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
ZZS3_k127_5362839_0	365046.Rta_34610	8.309e-274	860.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2VKRE@28216|Betaproteobacteria,4AACG@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
ZZS3_k127_5368092_5	1121116.KB894765_gene775	2.629e-50	181.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,4AB4P@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
ZZS3_k127_5368092_4	338969.Rfer_1753	1.037e-63	223.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,4ADXB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
ZZS3_k127_5368092_1	365046.Rta_28360	3.618e-177	561.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,4ABMP@80864|Comamonadaceae	28216|Betaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
ZZS3_k127_5368092_0	365046.Rta_28340	5.69e-283	876.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,4A9TZ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
ZZS3_k127_5368092_2	365046.Rta_28260	3.137e-97	322.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,2VSA4@28216|Betaproteobacteria,4ADGM@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
ZZS3_k127_5368092_3	365046.Rta_28250	1.368e-75	256.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,4AEAE@80864|Comamonadaceae	28216|Betaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
ZZS3_k127_5377911_14	1212548.B381_21216	5.381e-17	93.0	COG4944@1|root,COG4944@2|Bacteria,1MXEV@1224|Proteobacteria,1S7DP@1236|Gammaproteobacteria,1Z08U@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
ZZS3_k127_5377911_9	864073.HFRIS_024420	1.631e-55	212.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2VRBF@28216|Betaproteobacteria,4773F@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE9	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_5377911_10	1283300.ATXB01000002_gene2905	8.496e-55	210.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,1RWGQ@1236|Gammaproteobacteria,1XFV5@135618|Methylococcales	135618|Methylococcales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
ZZS3_k127_5377911_8	1245471.PCA10_31160	4.334e-60	225.0	COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,1S0G6@1236|Gammaproteobacteria,1YH3V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
ZZS3_k127_5377911_5	1149133.ppKF707_2899	3.126e-116	386.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1YHKE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
ZZS3_k127_5377911_11	338969.Rfer_1608	4.233e-35	136.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2VV7D@28216|Betaproteobacteria,4AF57@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
ZZS3_k127_5377911_0	345341.KUTG_02884	8.97e-224	715.0	COG1529@1|root,COG1529@2|Bacteria,2GIY7@201174|Actinobacteria,4DZMZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2,Fer2,Fer2_2
ZZS3_k127_5377911_2	365046.Rta_22690	1.768e-144	466.0	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,2VIIF@28216|Betaproteobacteria,4A9UA@80864|Comamonadaceae	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_5377911_15	365046.Rta_22680	4.994e-16	79.0	COG2104@1|root,COG2104@2|Bacteria,1PU95@1224|Proteobacteria,2WARC@28216|Betaproteobacteria,4AFWE@80864|Comamonadaceae	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ZZS3_k127_5377911_3	365046.Rta_22670	1.043e-133	433.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,4A9ZW@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
ZZS3_k127_5377911_12	1454004.AW11_01326	8.252e-29	125.0	COG2461@1|root,COG2461@2|Bacteria,1QX14@1224|Proteobacteria	1224|Proteobacteria	S	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS
ZZS3_k127_5377911_1	358220.C380_04975	7.535e-209	659.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,4AAMV@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ZZS3_k127_5377911_6	365046.Rta_32920	2.274e-101	346.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,4AA8J@80864|Comamonadaceae	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
ZZS3_k127_5377911_4	1123504.JQKD01000015_gene972	5.773e-128	416.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,4A9XQ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
ZZS3_k127_5377911_7	296591.Bpro_1338	1.469e-76	258.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,4A9Q3@80864|Comamonadaceae	28216|Betaproteobacteria	T	protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
ZZS3_k127_5377994_7	365046.Rta_26020	1.332e-129	420.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria,4A9WE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
ZZS3_k127_5377994_0	365046.Rta_26010	3.457e-287	893.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,4A9M7@80864|Comamonadaceae	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ZZS3_k127_5377994_8	1458275.AZ34_13770	7.857e-108	352.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,4AAXT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
ZZS3_k127_5377994_1	365046.Rta_25990	3.776e-267	825.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VM92@28216|Betaproteobacteria,4ACS4@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske 2Fe-2S domain protein	nagG	-	1.14.12.1,1.14.12.15,1.14.13.172	ko:K16319,ko:K18074,ko:K18242	ko00624,ko00626,ko00627,ko01100,ko01120,ko01220,map00624,map00626,map00627,map01100,map01120,map01220	M00624,M00637,M00638	R00823,R00825,R05148,R07709,R07710	RC00192,RC00270,RC00490	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS3_k127_5377994_9	365046.Rta_25980	4.76e-81	279.0	COG5517@1|root,COG5517@2|Bacteria,1RB82@1224|Proteobacteria,2VQ3X@28216|Betaproteobacteria,4ADRF@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM aromatic-ring-hydroxylating dioxygenase beta subunit	nagH	-	1.14.12.1,1.14.13.172	ko:K16320,ko:K18243	ko00626,ko00627,ko01120,map00626,map00627,map01120	M00637,M00638	R00823,R00825,R07709,R07710	RC00192,RC00490	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ring_hydroxyl_B,SnoaL_4
ZZS3_k127_5377994_18	365046.Rta_25970	1.007e-09	65.0	2DQDW@1|root,3367H@2|Bacteria,1NF2K@1224|Proteobacteria,2VWXB@28216|Betaproteobacteria,4AFDZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 17 kDa surface antigen	-	-	-	ko:K04062	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
ZZS3_k127_5377994_2	365046.Rta_25960	4.897e-192	615.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,4A9UM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall hydrolase autolysin	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
ZZS3_k127_5377994_12	1223521.BBJX01000004_gene2289	4.208e-64	239.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,4AEJQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
ZZS3_k127_5377994_3	365044.Pnap_1172	1.517e-166	538.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,4ABA5@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
ZZS3_k127_5377994_15	381666.H16_B0327	1.041e-23	108.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
ZZS3_k127_5377994_19	1397527.Q670_02925	2.964e-06	60.0	2ECI6@1|root,32W6D@2|Bacteria,1N4WJ@1224|Proteobacteria,1T4N5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5377994_6	365046.Rta_25940	2.048e-130	439.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2VIM5@28216|Betaproteobacteria,4AAR3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
ZZS3_k127_5377994_4	365046.Rta_25930	2.988e-158	552.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKQJ@28216|Betaproteobacteria,4AAKR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5377994_5	365044.Pnap_1174	3.276e-138	462.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,4A9Z6@80864|Comamonadaceae	28216|Betaproteobacteria	D	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS3_k127_5377994_11	1071679.BG57_23315	3.093e-68	237.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,1K202@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
ZZS3_k127_5377994_16	339670.Bamb_5049	1.532e-21	98.0	COG3794@1|root,COG3794@2|Bacteria,1MZHR@1224|Proteobacteria,2WFFZ@28216|Betaproteobacteria,1KI1J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
ZZS3_k127_5377994_10	339670.Bamb_5050	1.623e-76	268.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VR5K@28216|Betaproteobacteria,1K265@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_5377994_20	983917.RGE_16170	1.436e-05	49.0	2EGJB@1|root,33ABH@2|Bacteria,1NI1G@1224|Proteobacteria,2VXT5@28216|Betaproteobacteria,1KMR1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5377994_17	1458275.AZ34_12100	3.763e-11	69.0	2E860@1|root,332JG@2|Bacteria,1NDJ6@1224|Proteobacteria,2VWR3@28216|Betaproteobacteria,4AFVI@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5377994_14	397945.Aave_3333	9.296e-31	123.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,4AFG6@80864|Comamonadaceae	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS3_k127_5377994_13	1121035.AUCH01000002_gene1459	2.879e-38	155.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2VIWG@28216|Betaproteobacteria,2KX26@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ZZS3_k127_5392749_1	296591.Bpro_2329	4.899e-286	904.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VJKJ@28216|Betaproteobacteria,4ACG8@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
ZZS3_k127_5392749_6	365046.Rta_33015	1.058e-48	184.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5392749_0	365046.Rta_33020	0.0	1071.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9
ZZS3_k127_5392749_7	365046.Rta_33030	2.513e-46	171.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VRW4@28216|Betaproteobacteria,4AE7N@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_5392749_9	296591.Bpro_4299	1.367e-20	97.0	2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,2VU0U@28216|Betaproteobacteria,4AF5J@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5392749_8	296591.Bpro_4300	1.636e-32	127.0	COG3198@1|root,COG3198@2|Bacteria,1N8D0@1224|Proteobacteria,2VWBW@28216|Betaproteobacteria,4AFBX@80864|Comamonadaceae	28216|Betaproteobacteria	S	FixH	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
ZZS3_k127_5392749_2	296591.Bpro_4301	2.244e-224	703.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,4AB30@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
ZZS3_k127_5392749_3	296591.Bpro_4302	4.47e-161	511.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4A9QA@80864|Comamonadaceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
ZZS3_k127_5392749_10	1268622.AVS7_02017	4.287e-09	66.0	COG4736@1|root,COG4736@2|Bacteria,1NAVM@1224|Proteobacteria,2VX7I@28216|Betaproteobacteria,4AFC8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Cbb3-type cytochrome oxidase	-	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
ZZS3_k127_5392749_4	397945.Aave_1524	2.031e-113	369.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,4ABQK@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome c oxidase, cbb3-type, subunit II	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
ZZS3_k127_5392749_5	358220.C380_15575	1.28e-95	314.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,4AAKI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
ZZS3_k127_5394911_19	1532557.JL37_18575	2.815e-08	55.0	COG0583@1|root,COG0583@2|Bacteria,1P2I1@1224|Proteobacteria,2VT4T@28216|Betaproteobacteria,3T4U4@506|Alcaligenaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5394911_1	1424334.W822_07295	1.543e-221	715.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,3T5HE@506|Alcaligenaceae	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
ZZS3_k127_5394911_11	1424334.W822_07305	7.718e-87	298.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T3AR@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5394911_10	397945.Aave_4024	6.609e-106	372.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2VPD9@28216|Betaproteobacteria,4ACQE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
ZZS3_k127_5394911_5	543728.Vapar_3517	3.431e-195	619.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2VI1S@28216|Betaproteobacteria,4AAZP@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_5394911_16	1366050.N234_03235	4.081e-56	209.0	COG1802@1|root,COG1802@2|Bacteria,1RBC0@1224|Proteobacteria,2VV2K@28216|Betaproteobacteria,1K1NG@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_5394911_17	1366050.N234_03230	3.578e-23	101.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS3_k127_5394911_13	1157708.KB907462_gene956	2.475e-69	247.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5394911_3	1366050.N234_03220	1.175e-207	659.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VZZH@28216|Betaproteobacteria,1KGQ1@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS3_k127_5394911_8	1007105.PT7_3033	1.027e-146	493.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2W1IE@28216|Betaproteobacteria,3T1DH@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_5394911_2	1007105.PT7_3034	1.866e-212	671.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,3T1XI@506|Alcaligenaceae	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
ZZS3_k127_5394911_14	1380394.JADL01000001_gene2351	1.007e-60	218.0	COG0730@1|root,COG0730@2|Bacteria,1PJR4@1224|Proteobacteria,2TU14@28211|Alphaproteobacteria,2JWE3@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
ZZS3_k127_5394911_15	1366050.N234_03235	1.551e-57	211.0	COG1802@1|root,COG1802@2|Bacteria,1RBC0@1224|Proteobacteria,2VV2K@28216|Betaproteobacteria,1K1NG@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_5394911_4	543728.Vapar_3976	2.408e-201	638.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2VHNW@28216|Betaproteobacteria,4ACN9@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	metC2	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_5394911_0	1157708.KB907460_gene1364	1.432e-240	762.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2VH3U@28216|Betaproteobacteria,4ABAE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS3_k127_5394911_12	543728.Vapar_3973	1.24e-86	290.0	COG5553@1|root,COG5553@2|Bacteria,1RAI5@1224|Proteobacteria,2VQ11@28216|Betaproteobacteria,4ADPB@80864|Comamonadaceae	28216|Betaproteobacteria	S	metal-dependent enzyme of the double-stranded beta helix superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5394911_9	543728.Vapar_3972	2.597e-127	413.0	COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,2VH8X@28216|Betaproteobacteria,4ABYB@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5394911_6	296591.Bpro_2040	5.244e-168	532.0	COG3181@1|root,COG3181@2|Bacteria,1R8GA@1224|Proteobacteria,2VM7P@28216|Betaproteobacteria,4ACU1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5394911_7	296591.Bpro_2038	2.528e-150	483.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2VPD9@28216|Betaproteobacteria,4ADRD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
ZZS3_k127_5394911_18	253839.SSNG_00853	4.62e-16	79.0	COG0031@1|root,COG0031@2|Bacteria,2GNE4@201174|Actinobacteria	201174|Actinobacteria	E	cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_5395107_13	365046.Rta_05220	2.069e-24	115.0	COG1082@1|root,COG1082@2|Bacteria,1MVBP@1224|Proteobacteria,2VMTH@28216|Betaproteobacteria,4ACEM@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS3_k127_5395107_3	365046.Rta_05210	4.546e-154	489.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,4ABJC@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
ZZS3_k127_5395107_4	365046.Rta_05200	3.401e-139	445.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,2VJ0Z@28216|Betaproteobacteria,4AAEQ@80864|Comamonadaceae	28216|Betaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
ZZS3_k127_5395107_7	365046.Rta_05190	3.146e-116	390.0	COG0765@1|root,COG0765@2|Bacteria,1MVB6@1224|Proteobacteria,2VKX0@28216|Betaproteobacteria,4AB2D@80864|Comamonadaceae	28216|Betaproteobacteria	P	Polar amino acid ABC transporter, inner membrane	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
ZZS3_k127_5395107_6	365046.Rta_05180	2.323e-120	389.0	COG0765@1|root,COG0765@2|Bacteria,1MX2Y@1224|Proteobacteria,2VNP0@28216|Betaproteobacteria,4AA1Q@80864|Comamonadaceae	28216|Betaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
ZZS3_k127_5395107_2	365046.Rta_05170	3.971e-172	545.0	COG1609@1|root,COG1609@2|Bacteria,1P73T@1224|Proteobacteria,2VJ4H@28216|Betaproteobacteria,4AAJD@80864|Comamonadaceae	28216|Betaproteobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02525	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ZZS3_k127_5395107_8	614083.AWQR01000001_gene3029	1.013e-110	363.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2VK37@28216|Betaproteobacteria,4AAFN@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
ZZS3_k127_5395107_0	365046.Rta_05160	0.0	1545.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VHP1@28216|Betaproteobacteria,4AAN4@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE1	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
ZZS3_k127_5395107_10	365046.Rta_05150	1.453e-82	276.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria,4ADM2@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
ZZS3_k127_5395107_12	397945.Aave_4624	2.804e-63	221.0	COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,2VJAT@28216|Betaproteobacteria,4ACM5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
ZZS3_k127_5395107_14	397945.Aave_4624	2.966e-20	94.0	COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,2VJAT@28216|Betaproteobacteria,4ACM5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
ZZS3_k127_5395107_5	365046.Rta_05090	2.703e-123	409.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2VMEB@28216|Betaproteobacteria,4ABNF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Threonyl alanyl tRNA synthetase SAD	alaS_2	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
ZZS3_k127_5395107_1	365046.Rta_05080	5.185e-308	958.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,4AA54@80864|Comamonadaceae	28216|Betaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	1.8.1.8	ko:K04084,ko:K08344	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.5	-	-	DsbC,DsbD,Thioredoxin_7
ZZS3_k127_5395107_9	358220.C380_21480	8.435e-84	303.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,2VQ4B@28216|Betaproteobacteria,4ADII@80864|Comamonadaceae	28216|Betaproteobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS3_k127_5395107_11	358220.C380_21485	2.587e-66	231.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VSU7@28216|Betaproteobacteria,4AEDV@80864|Comamonadaceae	28216|Betaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
ZZS3_k127_5395107_15	232721.Ajs_3858	6.323e-17	81.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,4AACZ@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_5421753_12	397945.Aave_3369	3.484e-06	53.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,2VXSD@28216|Betaproteobacteria,4AFVR@80864|Comamonadaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
ZZS3_k127_5421753_13	1120958.AULD01000015_gene1391	0.0003696	50.0	COG4113@1|root,COG4113@2|Bacteria,2GUYZ@201174|Actinobacteria,4FSQ3@85023|Microbacteriaceae	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
ZZS3_k127_5421753_1	365046.Rta_19730	0.0	1023.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,4AAM6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
ZZS3_k127_5421753_5	595537.Varpa_2944	7.375e-97	321.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2VRAJ@28216|Betaproteobacteria,4AA4V@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Negative transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
ZZS3_k127_5421753_11	365046.Rta_19760	1.01e-12	74.0	2DTB3@1|root,33JHU@2|Bacteria,1NKUX@1224|Proteobacteria,2VXRF@28216|Betaproteobacteria,4AG1Z@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5421753_2	365046.Rta_19770	5.26e-223	704.0	COG0590@1|root,COG0596@1|root,COG0590@2|Bacteria,COG0596@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,4A9VR@80864|Comamonadaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
ZZS3_k127_5421753_4	365046.Rta_19780	3.095e-143	484.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2VHAS@28216|Betaproteobacteria,4AARA@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM peptidase U61, LD-carboxypeptidase A	ldcA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
ZZS3_k127_5421753_9	365046.Rta_19790	4.087e-41	154.0	2ED33@1|root,336ZZ@2|Bacteria,1NB4Z@1224|Proteobacteria,2VWEJ@28216|Betaproteobacteria,4AFGV@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5421753_6	296591.Bpro_1193	9.585e-95	325.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2VJI6@28216|Betaproteobacteria,4AAH2@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
ZZS3_k127_5421753_7	1144319.PMI16_00980	4.881e-80	276.0	28IJW@1|root,2Z8KR@2|Bacteria,1R45I@1224|Proteobacteria,2VK7H@28216|Betaproteobacteria,4763S@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	signal peptide protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5421753_8	1538295.JY96_08405	3.564e-49	180.0	COG1846@1|root,COG1846@2|Bacteria,1PW9W@1224|Proteobacteria,2VUDE@28216|Betaproteobacteria	28216|Betaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_5421753_0	1538295.JY96_08420	0.0	1089.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VIAZ@28216|Betaproteobacteria,1KPJ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
ZZS3_k127_5421753_3	365046.Rta_05270	1.098e-169	538.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,4AB6S@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
ZZS3_k127_5423578_4	1532557.JL37_02790	5.414e-107	349.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VM4C@28216|Betaproteobacteria,3T2UR@506|Alcaligenaceae	28216|Betaproteobacteria	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
ZZS3_k127_5423578_13	1123504.JQKD01000008_gene5332	1.266e-12	79.0	2DWUK@1|root,341YV@2|Bacteria,1NYVW@1224|Proteobacteria,2W3QH@28216|Betaproteobacteria,4AI5M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2917)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2917
ZZS3_k127_5423578_5	1123504.JQKD01000008_gene5333	8.33e-100	334.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VS0H@28216|Betaproteobacteria,4AGZJ@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5423578_14	365046.Rta_13040	1.022e-09	68.0	COG3291@1|root,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria	1224|Proteobacteria	DZ	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
ZZS3_k127_5423578_6	477184.KYC_15267	5.911e-84	293.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2VJE3@28216|Betaproteobacteria,3T5ZB@506|Alcaligenaceae	28216|Betaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
ZZS3_k127_5423578_11	365046.Rta_20730	1.198e-15	78.0	299GF@1|root,2ZWJ5@2|Bacteria,1P7QU@1224|Proteobacteria,2W5AW@28216|Betaproteobacteria,4AIR3@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5423578_2	365046.Rta_20710	3.639e-142	458.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,4ACKG@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Endonuclease exonuclease phosphatase	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
ZZS3_k127_5423578_12	365046.Rta_20680	2.799e-15	84.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
ZZS3_k127_5423578_7	1411123.JQNH01000001_gene263	4.145e-65	228.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2U7AN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
ZZS3_k127_5423578_1	1110502.TMO_2422	1.157e-155	497.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria,2JW6C@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS3_k127_5423578_9	595537.Varpa_3669	4.936e-39	150.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2VUKM@28216|Betaproteobacteria,4AF08@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM CHRD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
ZZS3_k127_5423578_0	296591.Bpro_3000	2.769e-214	677.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VIHU@28216|Betaproteobacteria,4ABD5@80864|Comamonadaceae	28216|Betaproteobacteria	CH	PFAM monooxygenase FAD-binding	mhpA_1	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_5423578_15	1123060.JONP01000010_gene2309	5.966e-08	64.0	29FTS@1|root,2ZP99@2|Bacteria,1P5VH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5423578_8	94624.Bpet0301	1.249e-46	179.0	COG1846@1|root,COG1846@2|Bacteria,1RIU0@1224|Proteobacteria,2VT84@28216|Betaproteobacteria,3T7JS@506|Alcaligenaceae	28216|Betaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
ZZS3_k127_5423578_3	1276756.AUEX01000003_gene702	2.832e-140	446.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,4A9VA@80864|Comamonadaceae	28216|Betaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
ZZS3_k127_5432683_2	296591.Bpro_4305	2.896e-225	698.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,4AAKI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
ZZS3_k127_5432683_12	296591.Bpro_4306	4.963e-14	77.0	COG3197@1|root,COG3197@2|Bacteria,1PUR2@1224|Proteobacteria,2VXMN@28216|Betaproteobacteria,4AG10@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
ZZS3_k127_5432683_0	296591.Bpro_4307	6.27e-308	959.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,4AAJW@80864|Comamonadaceae	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
ZZS3_k127_5432683_8	296591.Bpro_4308	1.37e-55	199.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,4AE1K@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_5432683_9	296591.Bpro_4309	1.231e-51	194.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,4ADXE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_5432683_7	296591.Bpro_1209	1.552e-68	243.0	COG2836@1|root,COG2836@2|Bacteria,1PN2Q@1224|Proteobacteria,2VNU4@28216|Betaproteobacteria,4AA6M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
ZZS3_k127_5432683_1	296591.Bpro_1208	1.435e-252	796.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,4ABSD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ZZS3_k127_5432683_5	1268622.AVS7_02012	2.86e-97	323.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,4ABIC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator crp fnr family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_5432683_11	296591.Bpro_1204	1.034e-16	84.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
ZZS3_k127_5432683_4	296591.Bpro_4294	3.094e-114	376.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,4AGD2@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_5432683_10	296591.Bpro_1169	4.134e-37	156.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VVNY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_5432683_6	296591.Bpro_4296	8.4e-95	324.0	COG2197@1|root,COG2197@2|Bacteria,1RENN@1224|Proteobacteria,2VR4J@28216|Betaproteobacteria,4AETN@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_5432683_3	296591.Bpro_4297	6.425e-140	458.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,4AANV@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
ZZS3_k127_5432683_13	614083.AWQR01000007_gene362	6.824e-14	75.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,4AENF@80864|Comamonadaceae	28216|Betaproteobacteria	T	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_5439680_14	296591.Bpro_0144	4.846e-10	59.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,2VSJM@28216|Betaproteobacteria,4AEJT@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_5439680_13	983917.RGE_21810	1.197e-22	102.0	2CBKU@1|root,32WBU@2|Bacteria,1N2RW@1224|Proteobacteria,2VWP8@28216|Betaproteobacteria,1KPKA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5439680_2	365046.Rta_09350	2.054e-173	552.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,2VI4T@28216|Betaproteobacteria,4ABUK@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, LysR	-	-	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5439680_7	887062.HGR_03082	4.812e-141	466.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VHFS@28216|Betaproteobacteria,4ACDY@80864|Comamonadaceae	28216|Betaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	gltI	-	-	ko:K10001	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
ZZS3_k127_5439680_10	1458275.AZ34_04380	1.623e-118	386.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,4ACFJ@80864|Comamonadaceae	28216|Betaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	gltJ	-	-	ko:K02029,ko:K10003	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
ZZS3_k127_5439680_11	1458275.AZ34_04385	3.734e-109	358.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,4AAVP@80864|Comamonadaceae	28216|Betaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	gltK	-	-	ko:K10002	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
ZZS3_k127_5439680_6	1121116.KB894772_gene1541	3.368e-142	456.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,4AAQY@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	gltL	-	-	ko:K10004	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	ABC_tran
ZZS3_k127_5439680_1	365046.Rta_09410	1.999e-186	587.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,4AAQZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_5439680_8	365046.Rta_09420	5.254e-131	438.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria,4AB6I@80864|Comamonadaceae	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
ZZS3_k127_5439680_12	365046.Rta_09430	1.027e-105	348.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,4AD57@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
ZZS3_k127_5439680_3	365046.Rta_09440	2.894e-158	502.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,4ABS5@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
ZZS3_k127_5439680_9	1268622.AVS7_03616	2.962e-127	421.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2VQ3C@28216|Betaproteobacteria,4AF28@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_5439680_5	358220.C380_03610	2.246e-145	476.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2VMS5@28216|Betaproteobacteria,4AD3W@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
ZZS3_k127_5439680_0	1100721.ALKO01000020_gene926	4.069e-259	826.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	Lactamase_B,NUDIX
ZZS3_k127_5439680_4	365046.Rta_09480	3.349e-146	496.0	COG3181@1|root,COG3181@2|Bacteria,1QVZV@1224|Proteobacteria,2VMXW@28216|Betaproteobacteria,4AAEP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5448264_5	1265502.KB905956_gene157	1.965e-102	340.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria	1224|Proteobacteria	P	Periplasmic solute binding protein	znuA	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
ZZS3_k127_5448264_8	1100720.ALKN01000044_gene2030	4.29e-41	170.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,4AI0E@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
ZZS3_k127_5448264_6	365046.Rta_02170	2.783e-93	311.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,2VQBX@28216|Betaproteobacteria,4AB1N@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
ZZS3_k127_5448264_0	365046.Rta_02130	0.0	1023.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,4A9NV@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_5448264_1	543728.Vapar_0393	5.38e-266	829.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,4AAKQ@80864|Comamonadaceae	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
ZZS3_k127_5448264_7	365046.Rta_02110	1.533e-45	166.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2VSM2@28216|Betaproteobacteria,4AEIA@80864|Comamonadaceae	28216|Betaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
ZZS3_k127_5448264_2	365046.Rta_02100	1.395e-206	649.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,4A9YY@80864|Comamonadaceae	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
ZZS3_k127_5448264_3	1095769.CAHF01000007_gene1650	1.389e-140	455.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2VH7E@28216|Betaproteobacteria,473GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
ZZS3_k127_5448264_4	365046.Rta_02080	3.962e-111	363.0	2CJTZ@1|root,32SAS@2|Bacteria,1N3WB@1224|Proteobacteria,2WFZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5448264_9	331869.BAL199_14527	2.84e-27	114.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,4BRHK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	-	-	1.1.1.27,1.1.1.350	ko:K00016,ko:K00073	ko00010,ko00230,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00230,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R02935,R02936,R03104	RC00031,RC00044,RC00169	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_2
ZZS3_k127_5456735_2	1532557.JL37_23235	1.115e-135	435.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VH34@28216|Betaproteobacteria,3T1PX@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
ZZS3_k127_5456735_10	296591.Bpro_3555	1.671e-60	215.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VRAE@28216|Betaproteobacteria,4ADZR@80864|Comamonadaceae	28216|Betaproteobacteria	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ZZS3_k127_5456735_4	365046.Rta_11180	7.673e-113	377.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,4AAQ9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Hemerythrin,PNP_phzG_C,Putative_PNPOx
ZZS3_k127_5456735_11	365046.Rta_11150	1.73e-53	190.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2VU3F@28216|Betaproteobacteria,4AF5Z@80864|Comamonadaceae	28216|Betaproteobacteria	P	Small Multidrug Resistance protein	sugE_1	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
ZZS3_k127_5456735_9	365046.Rta_11100	3.124e-69	240.0	COG3495@1|root,COG3495@2|Bacteria,1RFBI@1224|Proteobacteria,2VRJ9@28216|Betaproteobacteria,4AE16@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
ZZS3_k127_5456735_12	365046.Rta_11090	1.504e-21	110.0	2EBIQ@1|root,335J5@2|Bacteria,1N8P7@1224|Proteobacteria,2VX7H@28216|Betaproteobacteria,4AFDY@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5456735_1	365046.Rta_11080	9.339e-169	549.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,2VJWZ@28216|Betaproteobacteria,4AD20@80864|Comamonadaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_5456735_8	397945.Aave_2812	2.948e-72	259.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2VSZX@28216|Betaproteobacteria,4AE1F@80864|Comamonadaceae	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_5456735_5	365046.Rta_11060	5.709e-102	334.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VR6F@28216|Betaproteobacteria,4ADFU@80864|Comamonadaceae	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
ZZS3_k127_5456735_7	365046.Rta_11050	1.723e-74	258.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSH4@28216|Betaproteobacteria,4AEH9@80864|Comamonadaceae	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
ZZS3_k127_5456735_6	365046.Rta_11040	9.344e-101	334.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,4AA6X@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
ZZS3_k127_5456735_3	296591.Bpro_1668	8.134e-126	423.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,2VJVW@28216|Betaproteobacteria,4ACN0@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	nolF	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_5456735_0	614083.AWQR01000005_gene1233	6.162e-254	789.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_5469472_0	365046.Rta_37120	1.487e-302	935.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS3_k127_5469472_2	365046.Rta_37110	2.543e-149	485.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,4AAUQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_5469472_1	365046.Rta_37100	3.259e-169	545.0	COG1538@1|root,COG1538@2|Bacteria,1P0S2@1224|Proteobacteria,2VH06@28216|Betaproteobacteria,4AAJB@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	tolC2	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS3_k127_5469472_3	365046.Rta_37080	4.016e-75	254.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,4A9PB@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
ZZS3_k127_547456_8	365046.Rta_29090	1.01e-107	351.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,4A9JB@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
ZZS3_k127_547456_12	338969.Rfer_1272	4.619e-30	129.0	2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,2WAGW@28216|Betaproteobacteria,4AEUM@80864|Comamonadaceae	28216|Betaproteobacteria	S	CNP1-like family	-	-	-	-	-	-	-	-	-	-	-	-	CNP1
ZZS3_k127_547456_7	365046.Rta_29070	4.713e-118	382.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,4AB18@80864|Comamonadaceae	28216|Betaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
ZZS3_k127_547456_0	365046.Rta_29060	0.0	1045.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,4A9WD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
ZZS3_k127_547456_10	365046.Rta_29050	1.132e-100	338.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,4A9JX@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_547456_2	365046.Rta_29040	3.439e-183	576.0	COG0466@1|root,COG0466@2|Bacteria,1MWQ9@1224|Proteobacteria,2VJKY@28216|Betaproteobacteria,4AB5F@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM AAA ATPase central domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
ZZS3_k127_547456_11	596154.Alide2_0898	6.733e-57	199.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,4AEI1@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
ZZS3_k127_547456_9	1123255.JHYS01000006_gene257	2.01e-103	360.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,4AA7K@80864|Comamonadaceae	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
ZZS3_k127_547456_3	1157708.KB907458_gene1822	4.588e-179	567.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,4AADP@80864|Comamonadaceae	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS3_k127_547456_1	365046.Rta_29000	1.385e-230	718.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,4ABC5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
ZZS3_k127_547456_13	365046.Rta_28990	5.789e-21	99.0	2E2ZU@1|root,32Y0F@2|Bacteria,1N83P@1224|Proteobacteria,2VW5D@28216|Betaproteobacteria,4AFGW@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_547456_6	1268622.AVS7_02182	1.429e-119	388.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2VH23@28216|Betaproteobacteria,4AA0Q@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0246 family	yaaA	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
ZZS3_k127_547456_4	365046.Rta_28970	5.384e-153	505.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2VK5Y@28216|Betaproteobacteria,4AAXY@80864|Comamonadaceae	28216|Betaproteobacteria	O	SMART Prolyl 4-hydroxylase, alpha subunit	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
ZZS3_k127_547456_5	365046.Rta_28960	1.391e-147	469.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,4AA88@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
ZZS3_k127_5508920_0	365046.Rta_26630	6.246e-307	949.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,4AB7E@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS3_k127_5508920_2	365046.Rta_26640	1.03e-135	437.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,2VH2D@28216|Betaproteobacteria,4AB5G@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glycosyl transferase, family	trpD3	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
ZZS3_k127_5508920_3	365046.Rta_26650	1.179e-113	380.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,4AAU2@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
ZZS3_k127_5508920_1	365046.Rta_26670	9.571e-210	657.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,4AAGJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
ZZS3_k127_5508920_5	1265502.KB905931_gene1684	1.106e-34	134.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,4AEXE@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ZZS3_k127_5508920_4	365046.Rta_26685	1.221e-68	236.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,4ADG9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
ZZS3_k127_5579629_11	365046.Rta_36050	2.209e-103	336.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,4AA16@80864|Comamonadaceae	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
ZZS3_k127_5579629_18	365046.Rta_36040	3.753e-67	230.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,4ADY3@80864|Comamonadaceae	28216|Betaproteobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
ZZS3_k127_5579629_27	598659.NAMH_1184	2.952e-06	59.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
ZZS3_k127_5579629_25	338963.Pcar_2061	6.079e-09	64.0	COG2340@1|root,COG2340@2|Bacteria,1NJB9@1224|Proteobacteria,42Y4H@68525|delta/epsilon subdivisions,2WSKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5579629_22	497964.CfE428DRAFT_6505	1.386e-17	89.0	COG0835@1|root,COG0835@2|Bacteria,46W87@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
ZZS3_k127_5579629_14	296591.Bpro_2459	8.936e-85	298.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,2W8ZD@28216|Betaproteobacteria,4AFA1@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
ZZS3_k127_5579629_23	290397.Adeh_1195	3.997e-17	96.0	COG0835@1|root,COG0835@2|Bacteria,1NHQM@1224|Proteobacteria,4323N@68525|delta/epsilon subdivisions,2WXPS@28221|Deltaproteobacteria,2YW58@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS3_k127_5579629_16	269799.Gmet_2709	4.038e-80	294.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N1S@68525|delta/epsilon subdivisions,2WK7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp40H-21	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,dCache_1
ZZS3_k127_5579629_7	443143.GM18_2208	1.445e-133	451.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
ZZS3_k127_5579629_17	1120999.JONM01000007_gene1716	4.037e-75	267.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VPEC@28216|Betaproteobacteria,2KSWG@206351|Neisseriales	206351|Neisseriales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
ZZS3_k127_5579629_13	269799.Gmet_2712	1.065e-96	345.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CAV@68525|delta/epsilon subdivisions,2X7MB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_5579629_26	176299.Atu4300	7.557e-09	68.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,4BCQG@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_5579629_15	365046.Rta_18730	2.911e-81	279.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VQAN@28216|Betaproteobacteria,4AF7J@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_5579629_24	365046.Rta_20680	2.054e-10	70.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
ZZS3_k127_5579629_6	1254432.SCE1572_40270	1.065e-134	432.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,42SXE@68525|delta/epsilon subdivisions,2WP6W@28221|Deltaproteobacteria,2YXS6@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
ZZS3_k127_5579629_3	338969.Rfer_4154	3.633e-166	537.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,2VH0A@28216|Betaproteobacteria,4ABGE@80864|Comamonadaceae	28216|Betaproteobacteria	F	TIGRFAM Formiminoglutamate deiminase	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_5579629_9	338969.Rfer_4155	7.809e-114	383.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2VK2Y@28216|Betaproteobacteria,4A9MP@80864|Comamonadaceae	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	hutG	-	3.5.1.68,3.5.3.8	ko:K01458,ko:K01479	ko00340,ko00630,ko01100,map00340,map00630,map01100	M00045	R00525,R02285	RC00165,RC00221,RC00323,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
ZZS3_k127_5579629_4	267608.RSc2644	8.843e-166	530.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2VK8A@28216|Betaproteobacteria,1JZYP@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
ZZS3_k127_5579629_19	338969.Rfer_4156	5.078e-43	174.0	COG3758@1|root,COG3758@2|Bacteria,1RH9G@1224|Proteobacteria,2VS40@28216|Betaproteobacteria,4AE7S@80864|Comamonadaceae	28216|Betaproteobacteria	S	HutD	-	-	-	ko:K09975	-	-	-	-	ko00000	-	-	-	HutD
ZZS3_k127_5579629_12	296591.Bpro_1165	3.91e-103	340.0	COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,2VK47@28216|Betaproteobacteria,4AJ6A@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA	hutC	-	-	ko:K05836	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
ZZS3_k127_5579629_0	296591.Bpro_1164	0.0	1041.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2VK3E@28216|Betaproteobacteria,4ABE7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
ZZS3_k127_5579629_2	296591.Bpro_1160	3.154e-237	756.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2VJB1@28216|Betaproteobacteria,4AAID@80864|Comamonadaceae	28216|Betaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
ZZS3_k127_5579629_5	1411123.JQNH01000001_gene2359	7.063e-150	479.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	MA20_34190	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
ZZS3_k127_5579629_8	420324.KI911948_gene9124	9.948e-126	406.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria,1JZ54@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	MA20_34185	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ZZS3_k127_5579629_10	670292.JH26_07250	1.171e-112	382.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,1JUFY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM ABC transporter	MA20_34180	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
ZZS3_k127_5579629_21	1123504.JQKD01000034_gene2746	7.262e-18	85.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,4AG0G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5579629_20	1500894.JQNN01000001_gene879	4.337e-23	109.0	2DNIN@1|root,32XPX@2|Bacteria,1N56X@1224|Proteobacteria,2VU83@28216|Betaproteobacteria,477W6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
ZZS3_k127_5579629_1	365046.Rta_04130	2.401e-305	938.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,4A9PE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
ZZS3_k127_5587842_6	987059.RBXJA2T_19341	2.488e-55	199.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2VN04@28216|Betaproteobacteria,1KNGM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
ZZS3_k127_5587842_4	365046.Rta_05770	5.379e-106	350.0	COG0740@1|root,COG0740@2|Bacteria,1RBNX@1224|Proteobacteria,2VKY1@28216|Betaproteobacteria,4ACPX@80864|Comamonadaceae	28216|Betaproteobacteria	OU	ATP-dependent Clp protease proteolytic subunit	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ZZS3_k127_5587842_2	596154.Alide2_0659	4.805e-129	450.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,4AAU3@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
ZZS3_k127_5587842_3	365046.Rta_06920	7.339e-109	357.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2VK8J@28216|Betaproteobacteria,4ABGG@80864|Comamonadaceae	28216|Betaproteobacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
ZZS3_k127_5587842_0	365046.Rta_06910	1.704e-284	880.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,4A9S8@80864|Comamonadaceae	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
ZZS3_k127_5587842_1	365046.Rta_06880	6.986e-180	569.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,2W01H@28216|Betaproteobacteria,4AGE3@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
ZZS3_k127_5587842_5	745310.G432_06405	6.488e-81	271.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2K3ZJ@204457|Sphingomonadales	204457|Sphingomonadales	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
ZZS3_k127_56482_10	1235457.C404_03105	5.562e-101	337.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,1K3GF@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	abmC	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_56482_0	365046.Rta_18140	0.0	1367.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,4ACF4@80864|Comamonadaceae	28216|Betaproteobacteria	CH	PFAM NADH flavin oxidoreductase NADH oxidase	abmA	-	1.14.13.40,1.3.1.34	ko:K00219,ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
ZZS3_k127_56482_2	365046.Rta_18130	2.941e-179	566.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2VHCA@28216|Betaproteobacteria,4A9MT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
ZZS3_k127_56482_12	1097668.BYI23_C008530	9.048e-96	323.0	COG1414@1|root,COG1414@2|Bacteria,1MXY8@1224|Proteobacteria,2VM0I@28216|Betaproteobacteria,1KFIS@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_56482_9	1268622.AVS7_03085	8.262e-109	391.0	COG1024@1|root,COG1024@2|Bacteria,1R7QG@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_56482_7	1268622.AVS7_03086	1.72e-129	421.0	COG3181@1|root,COG3181@2|Bacteria,1NS37@1224|Proteobacteria,2W061@28216|Betaproteobacteria,4AHAE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_56482_1	1268622.AVS7_03087	2.981e-277	860.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VHE3@28216|Betaproteobacteria,4ADC5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_56482_5	1268622.AVS7_03088	1.01e-135	434.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,4A9TB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS3_k127_56482_15	1411123.JQNH01000001_gene573	2.474e-74	254.0	COG3703@1|root,COG3703@2|Bacteria,1RCP4@1224|Proteobacteria,2UREI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_56482_8	1411123.JQNH01000001_gene574	5.797e-120	403.0	COG0834@1|root,COG0834@2|Bacteria,1N50R@1224|Proteobacteria,2TV4K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
ZZS3_k127_56482_18	335659.S23_40170	1.281e-66	239.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2U2S8@28211|Alphaproteobacteria,3K646@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
ZZS3_k127_56482_13	1082931.KKY_2360	1.506e-93	341.0	COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,2V8C0@28211|Alphaproteobacteria,3N8TB@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
ZZS3_k127_56482_14	1082931.KKY_2359	7.72e-92	314.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
ZZS3_k127_56482_17	1411123.JQNH01000001_gene577	4.624e-68	237.0	COG0346@1|root,COG0346@2|Bacteria,1RHBM@1224|Proteobacteria,2U9Q5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
ZZS3_k127_56482_20	1082931.KKY_2358	1.741e-62	226.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_56482_21	195105.CN97_11910	6.976e-08	58.0	2EG8Q@1|root,33A0I@2|Bacteria,1NJUE@1224|Proteobacteria,2UJNF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_56482_16	1144342.PMI40_01764	1.679e-69	250.0	COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria	1224|Proteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_56482_3	596153.Alide_2233	2.176e-138	445.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VNQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_56482_11	596153.Alide_2234	1.257e-97	325.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	DUF1932,NAD_binding_2,RraA-like
ZZS3_k127_56482_4	596153.Alide_2235	4.911e-136	454.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VN65@28216|Betaproteobacteria,4A9Q0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
ZZS3_k127_56482_6	596154.Alide2_2431	2.369e-135	441.0	COG3181@1|root,COG3181@2|Bacteria,1NS37@1224|Proteobacteria,2W061@28216|Betaproteobacteria,4AHAE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_56482_19	595537.Varpa_4883	3.949e-65	224.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,4AAYY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS3_k127_5690594_0	365044.Pnap_0094	6.417e-225	703.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2VH1D@28216|Betaproteobacteria,4A9ZE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD dependent oxidoreductase	dadA4	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2
ZZS3_k127_5690594_2	365046.Rta_01200	3.586e-155	495.0	COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,2VJPA@28216|Betaproteobacteria,4ACDV@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	argP	-	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5690594_3	365046.Rta_01240	3.454e-133	437.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VIHN@28216|Betaproteobacteria,4AB9K@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_5690594_5	614083.AWQR01000038_gene1391	1.705e-50	186.0	COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2VV2W@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	Globin
ZZS3_k127_5690594_1	614083.AWQR01000038_gene1392	8.226e-201	634.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9V8@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator	yfhA	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_5690594_4	614083.AWQR01000055_gene1981	6.434e-80	289.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WI03@28216|Betaproteobacteria	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
ZZS3_k127_5690594_6	296591.Bpro_0157	2.847e-39	147.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VNHK@28216|Betaproteobacteria,4AGFZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5709672_9	365046.Rta_23900	2.094e-92	304.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,4AAPA@80864|Comamonadaceae	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS3_k127_5709672_24	1049564.TevJSym_ab00050	0.0002009	53.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	sphX	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
ZZS3_k127_5709672_11	398578.Daci_1809	9.883e-80	273.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VHQ0@28216|Betaproteobacteria,4ACM6@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_5709672_1	365046.Rta_11920	1.351e-217	681.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,4AC8W@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ZZS3_k127_5709672_17	365046.Rta_30930	4.743e-40	156.0	COG1846@1|root,COG1846@2|Bacteria,1N5CQ@1224|Proteobacteria,2VT0D@28216|Betaproteobacteria,4AF4J@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_5709672_18	290398.Csal_0325	3.485e-32	129.0	COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,1S8CE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	ligA_1	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA
ZZS3_k127_5709672_6	290398.Csal_0324	2.048e-107	361.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,1XMT5@135619|Oceanospirillales	135619|Oceanospirillales	S	PFAM Extradiol ring-cleavage dioxygenase, class III	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
ZZS3_k127_5709672_4	234267.Acid_0252	2.447e-129	438.0	COG0654@1|root,COG0654@2|Bacteria,3Y4BW@57723|Acidobacteria	57723|Acidobacteria	CH	FAD binding domain	-	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_5709672_7	1123504.JQKD01000013_gene1070	3.28e-106	372.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VI0T@28216|Betaproteobacteria,4ABD1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5709672_19	864073.HFRIS_005188	2.791e-29	126.0	COG1376@1|root,COG1376@2|Bacteria,1RAMJ@1224|Proteobacteria,2VQ9N@28216|Betaproteobacteria,476BU@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5709672_23	391038.Bphy_2091	8.591e-10	62.0	2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria,1KB1T@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3096
ZZS3_k127_5709672_5	365046.Rta_23870	3.094e-128	422.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2VP8F@28216|Betaproteobacteria,4AD6N@80864|Comamonadaceae	28216|Betaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_5709672_20	365046.Rta_23860	1.018e-23	106.0	COG3861@1|root,COG3861@2|Bacteria,1P6SY@1224|Proteobacteria	1224|Proteobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5709672_13	365046.Rta_23850	4.522e-63	222.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2VV6B@28216|Betaproteobacteria	28216|Betaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS3_k127_5709672_8	296591.Bpro_2825	6.59e-105	370.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1RAZ4@1224|Proteobacteria,2VQNX@28216|Betaproteobacteria,4AJDQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
ZZS3_k127_5709672_2	365046.Rta_23840	8.805e-192	608.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2WGJT@28216|Betaproteobacteria,4AJZH@80864|Comamonadaceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	fsr1	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS3_k127_5709672_0	296591.Bpro_2822	4.761e-219	692.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,4ABSK@80864|Comamonadaceae	28216|Betaproteobacteria	U	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
ZZS3_k127_5709672_15	296591.Bpro_2821	4.294e-45	172.0	2CEXV@1|root,32S0S@2|Bacteria,1MZKB@1224|Proteobacteria,2VU8J@28216|Betaproteobacteria,4AFP3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Type II secretion system protein B	gspB	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
ZZS3_k127_5709672_16	296591.Bpro_2820	8.593e-43	175.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2VVI3@28216|Betaproteobacteria,4AHZ4@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5709672_3	296591.Bpro_2819	7.891e-136	437.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria,4AGTV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_5709672_14	1458275.AZ34_11325	2.588e-56	202.0	COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,2VUGF@28216|Betaproteobacteria,4AEVH@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ZZS3_k127_5709672_10	365046.Rta_23790	1.008e-80	278.0	2DZJI@1|root,32VCD@2|Bacteria,1N154@1224|Proteobacteria,2W3QP@28216|Betaproteobacteria,4AI10@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5709672_12	365046.Rta_23780	6.539e-64	224.0	COG1664@1|root,COG1664@2|Bacteria,1N26P@1224|Proteobacteria,2VSIS@28216|Betaproteobacteria,4AE27@80864|Comamonadaceae	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ZZS3_k127_5709672_22	365046.Rta_23770	4.895e-15	74.0	COG1082@1|root,COG1082@2|Bacteria,1Q173@1224|Proteobacteria,2VK1Z@28216|Betaproteobacteria,4AAG1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS3_k127_5815017_5	1268622.AVS7_02919	7.659e-18	82.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,4AAHE@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
ZZS3_k127_5815017_1	365046.Rta_08440	3.971e-135	434.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,4A9JZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
ZZS3_k127_5815017_0	365046.Rta_08430	6.091e-258	800.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,4AAVH@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
ZZS3_k127_5815017_3	365046.Rta_08420	9.057e-113	365.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,4AAIY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
ZZS3_k127_5815017_4	296591.Bpro_0820	7.773e-59	208.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,4ADW1@80864|Comamonadaceae	28216|Betaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
ZZS3_k127_5815017_2	1223521.BBJX01000006_gene1694	9.565e-127	411.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,4ABB1@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
ZZS3_k127_583391_4	887062.HGR_12127	7.88e-155	491.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,4A9UY@80864|Comamonadaceae	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_583391_2	296591.Bpro_1094	4.11e-211	662.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,4ABHM@80864|Comamonadaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ZZS3_k127_583391_11	1223521.BBJX01000015_gene242	4.012e-17	96.0	2F6J3@1|root,33Z20@2|Bacteria,1N69G@1224|Proteobacteria,2VVCC@28216|Betaproteobacteria,4AEZH@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_583391_0	365046.Rta_09920	9.778e-280	864.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,4ABF1@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
ZZS3_k127_583391_7	614083.AWQR01000001_gene3031	1.497e-79	304.0	COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
ZZS3_k127_583391_6	614083.AWQR01000045_gene2050	4.072e-91	308.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2VKIK@28216|Betaproteobacteria,4AACB@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31,1.1.1.411	ko:K00020,ko:K08319	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_583391_5	1117647.M5M_15825	6.526e-120	407.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1J9SB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_583391_1	935557.ATYB01000008_gene4833	1.261e-218	727.0	COG2267@1|root,COG2303@1|root,COG3540@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,COG3540@2|Bacteria,1QQ8F@1224|Proteobacteria,2U7D4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EI	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
ZZS3_k127_583391_9	935557.ATYB01000008_gene4833	8.615e-38	160.0	COG2267@1|root,COG2303@1|root,COG3540@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,COG3540@2|Bacteria,1QQ8F@1224|Proteobacteria,2U7D4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EI	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
ZZS3_k127_583391_10	626887.J057_10951	2.662e-34	139.0	COG2197@1|root,COG2197@2|Bacteria,1PXTY@1224|Proteobacteria,1RMPW@1236|Gammaproteobacteria,466JI@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	agmR	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
ZZS3_k127_583391_3	614083.AWQR01000045_gene2051	2.771e-165	522.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,4AAV9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
ZZS3_k127_5873733_6	365046.Rta_34930	6.49e-39	145.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,4AC0U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
ZZS3_k127_5873733_4	365046.Rta_34940	4.313e-156	496.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJ0Q@28216|Betaproteobacteria,4A9RD@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_5873733_3	1276756.AUEX01000012_gene3549	5.397e-168	531.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2VIID@28216|Betaproteobacteria,4AACH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_5873733_2	1100720.ALKN01000033_gene652	1.768e-188	593.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VHRM@28216|Betaproteobacteria,4AA0E@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_5873733_0	1265502.KB905934_gene3299	2.103e-250	778.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2VI33@28216|Betaproteobacteria,4A9NB@80864|Comamonadaceae	28216|Betaproteobacteria	E	Amino acid amide ABC transporter substrate-binding protein, HAAT family	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_5873733_5	1219031.BBJR01000072_gene1141	5.018e-153	487.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,4A9R5@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_5873733_1	365046.Rta_34990	2.778e-202	653.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,4AC0Z@80864|Comamonadaceae	28216|Betaproteobacteria	H	AMP-binding enzyme	paaK_2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
ZZS3_k127_5873733_7	1219031.BBJR01000072_gene1139	1.07e-21	97.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,4AC3Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5878427_7	296591.Bpro_0561	3.187e-95	317.0	COG3971@1|root,COG3971@2|Bacteria,1QJM1@1224|Proteobacteria,2VQ3F@28216|Betaproteobacteria,4AE3H@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_5878427_4	504832.OCAR_6691	1.528e-183	582.0	COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria,3JWCH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5878427_5	296591.Bpro_0560	1.247e-180	569.0	COG3181@1|root,COG3181@2|Bacteria,1PZK3@1224|Proteobacteria,2VJ65@28216|Betaproteobacteria,4ABJ7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_5878427_1	296591.Bpro_0559	2.427e-210	662.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VN08@28216|Betaproteobacteria,4AE4D@80864|Comamonadaceae	28216|Betaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_5878427_0	296591.Bpro_0558	6.652e-231	731.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VNXG@28216|Betaproteobacteria,4AD7N@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_5878427_8	296591.Bpro_0557	2.337e-90	319.0	COG3090@1|root,COG3090@2|Bacteria,1QU8D@1224|Proteobacteria,2WGIS@28216|Betaproteobacteria,4AFRK@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_5878427_2	296591.Bpro_0556	7.304e-196	634.0	COG1638@1|root,COG1638@2|Bacteria,1MUBS@1224|Proteobacteria,2VJS6@28216|Betaproteobacteria,4AC55@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_5878427_6	381666.H16_B0882	1.941e-140	471.0	COG1638@1|root,COG1638@2|Bacteria,1MUBS@1224|Proteobacteria,2VJS6@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TRAP-type C4-dicarboxylate transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_5878427_3	296591.Bpro_0555	4.843e-190	597.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4ACPD@80864|Comamonadaceae	28216|Betaproteobacteria	G	Trap dicarboxylate transporter, dctm subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_5891604_4	977880.RALTA_B1401	1.168e-54	203.0	2ATF0@1|root,31IYG@2|Bacteria,1MYJT@1224|Proteobacteria,2VSVD@28216|Betaproteobacteria,1K8PN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2846
ZZS3_k127_5891604_5	267608.RSp1533	3.226e-23	105.0	2DQY8@1|root,339CK@2|Bacteria,1ND09@1224|Proteobacteria,2VXIW@28216|Betaproteobacteria,1KA9E@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5891604_0	365046.Rta_34280	3.293e-205	650.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,4A9MM@80864|Comamonadaceae	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
ZZS3_k127_5891604_3	614083.AWQR01000029_gene2169	1.858e-102	357.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,2VKM3@28216|Betaproteobacteria,4AG3Q@80864|Comamonadaceae	28216|Betaproteobacteria	T	7TMR-DISM extracellular 2	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
ZZS3_k127_5891604_2	365046.Rta_34290	1.164e-133	431.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,2VI15@28216|Betaproteobacteria,4AAJF@80864|Comamonadaceae	28216|Betaproteobacteria	S	MOSC domain protein beta barrel domain protein	ycbX	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
ZZS3_k127_5891604_1	365046.Rta_34300	1.67e-161	517.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,4AAIA@80864|Comamonadaceae	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiF	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,SE
ZZS3_k127_5919181_4	365046.Rta_07380	6.058e-45	165.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,4AB1X@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gst8	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
ZZS3_k127_5919181_3	1157708.KB907452_gene4021	5.012e-53	191.0	COG1285@1|root,COG1285@2|Bacteria,1RH5E@1224|Proteobacteria,2VT66@28216|Betaproteobacteria,4AEST@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
ZZS3_k127_5919181_0	365046.Rta_07430	1.402e-307	955.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,4A9QW@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Lytic transglycosylase catalytic	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
ZZS3_k127_5919181_2	887062.HGR_06621	1.846e-93	342.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria,4AC4U@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
ZZS3_k127_5919181_1	365046.Rta_07460	3.859e-179	566.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VIST@28216|Betaproteobacteria,4AARE@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_5919181_5	365046.Rta_07470	3.779e-14	76.0	2EI57@1|root,33BWJ@2|Bacteria,1NGN3@1224|Proteobacteria,2VY7R@28216|Betaproteobacteria,4AFVU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2917)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2917
ZZS3_k127_5944789_20	365046.Rta_03320	4.545e-49	178.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,4A9J7@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
ZZS3_k127_5944789_12	596153.Alide_0418	3.406e-81	271.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,4ADF8@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
ZZS3_k127_5944789_26	365046.Rta_03340	3.951e-23	105.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,4AFHC@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
ZZS3_k127_5944789_23	365046.Rta_03350	5.987e-43	158.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,4AEXY@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
ZZS3_k127_5944789_9	1157708.KB907463_gene839	1.078e-91	303.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2VQDH@28216|Betaproteobacteria,4ABE4@80864|Comamonadaceae	28216|Betaproteobacteria	O	Redoxin domain protein	ahp1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
ZZS3_k127_5944789_13	1276756.AUEX01000031_gene142	2.456e-80	271.0	COG0454@1|root,COG0456@2|Bacteria,1PNX8@1224|Proteobacteria,2VR63@28216|Betaproteobacteria,4ADZB@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_5944789_18	1288494.EBAPG3_3540	1.536e-52	203.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS3_k127_5944789_14	365046.Rta_03400	7.02e-75	255.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,4ADIM@80864|Comamonadaceae	28216|Betaproteobacteria	CO	Redoxin domain protein	resA_2	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
ZZS3_k127_5944789_7	365046.Rta_03410	5.107e-118	405.0	COG0596@1|root,COG0596@2|Bacteria,1R3U1@1224|Proteobacteria,2VNZR@28216|Betaproteobacteria,4A9XT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS3_k127_5944789_1	365046.Rta_03420	1.218e-230	720.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,4AAG0@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_5944789_3	365046.Rta_03430	2.283e-175	558.0	COG0477@1|root,COG2814@2|Bacteria,1QUY6@1224|Proteobacteria,2VNN5@28216|Betaproteobacteria,4AAMP@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_5944789_15	365046.Rta_03440	4.314e-73	248.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,4AEDR@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	manX	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
ZZS3_k127_5944789_25	1121116.KB894778_gene1909	1.073e-36	140.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,4AF0H@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM phosphocarrier, HPr family	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ZZS3_k127_5944789_0	365046.Rta_03460	1e-321	992.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,4AA7F@80864|Comamonadaceae	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
ZZS3_k127_5944789_6	365046.Rta_03475	1.791e-131	425.0	COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,2VMH0@28216|Betaproteobacteria,4AAMY@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_5944789_10	1458275.AZ34_00550	1.316e-90	306.0	COG2207@1|root,COG2207@2|Bacteria,1RCXI@1224|Proteobacteria,2VS7M@28216|Betaproteobacteria,4AE2X@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
ZZS3_k127_5944789_2	365046.Rta_03500	2.144e-195	613.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,4AAQD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
ZZS3_k127_5944789_8	365044.Pnap_0243	1.329e-108	361.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,4ABST@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS3_k127_5944789_22	1123504.JQKD01000003_gene530	6.963e-45	164.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,4AEUT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0250 family	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
ZZS3_k127_5944789_5	296591.Bpro_0317	1.151e-132	428.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,4ACXI@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Amino-transferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
ZZS3_k127_5944789_21	75379.Tint_2762	1.996e-46	173.0	COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,2VU1V@28216|Betaproteobacteria,1KP3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
ZZS3_k127_5944789_19	543728.Vapar_4877	1.201e-49	182.0	COG3312@1|root,COG3312@2|Bacteria,1RJ13@1224|Proteobacteria,2VT87@28216|Betaproteobacteria,4AEH3@80864|Comamonadaceae	28216|Betaproteobacteria	C	ATP synthase	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
ZZS3_k127_5944789_4	543728.Vapar_4876	5.371e-144	461.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,4AARU@80864|Comamonadaceae	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
ZZS3_k127_5944789_24	864051.BurJ1DRAFT_0314	4.842e-38	152.0	COG0636@1|root,COG0636@2|Bacteria,1R359@1224|Proteobacteria,2WIFK@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
ZZS3_k127_5944789_17	543728.Vapar_4874	4.47e-63	222.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,4ADHJ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
ZZS3_k127_5944789_11	365046.Rta_03580	3.896e-83	279.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,4ADN2@80864|Comamonadaceae	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
ZZS3_k127_5944789_16	365046.Rta_03590	1.039e-68	234.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,4AAYA@80864|Comamonadaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
ZZS3_k127_5950210_16	543728.Vapar_4029	1.004e-15	77.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria,4AERE@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
ZZS3_k127_5950210_4	365046.Rta_30300	2.004e-145	481.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2VK9P@28216|Betaproteobacteria,4AACF@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_5950210_3	365046.Rta_30310	4.915e-171	543.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,4AAMX@80864|Comamonadaceae	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
ZZS3_k127_5950210_10	365046.Rta_30320	1.177e-70	246.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,4ADNQ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
ZZS3_k127_5950210_7	1268622.AVS7_02614	1.394e-104	345.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,4ABDV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
ZZS3_k127_5950210_8	365046.Rta_30335	1.285e-87	305.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,4ADI1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Smr protein MutS2	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
ZZS3_k127_5950210_5	365046.Rta_30340	7.247e-139	448.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,2VKBX@28216|Betaproteobacteria,4ACSP@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_5950210_9	365046.Rta_30350	1.732e-82	278.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2WFQ4@28216|Betaproteobacteria,4ADMI@80864|Comamonadaceae	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS3_k127_5950210_11	365046.Rta_30360	4.159e-70	239.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,4ADYV@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM globin	yjbI	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
ZZS3_k127_5950210_0	365046.Rta_30400	0.0	1323.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,4AB0J@80864|Comamonadaceae	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_5950210_6	365046.Rta_30460	2.057e-131	424.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,4AA9S@80864|Comamonadaceae	28216|Betaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
ZZS3_k127_5950210_1	196367.JNFG01000201_gene2901	1.671e-175	562.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2VNYW@28216|Betaproteobacteria,1K78V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
ZZS3_k127_5950210_13	946483.Cenrod_2330	5.831e-37	143.0	COG1813@1|root,COG1813@2|Bacteria,1QVBI@1224|Proteobacteria,2VVCF@28216|Betaproteobacteria,4AEYJ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
ZZS3_k127_5950210_14	365046.Rta_30470	2.027e-23	116.0	2CKKR@1|root,332MC@2|Bacteria,1NCAT@1224|Proteobacteria,2VW6M@28216|Betaproteobacteria,4AEWU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5950210_2	365046.Rta_30480	1.272e-174	559.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,4AB36@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM Formate dehydrogenase, gamma subunit	fdhC	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
ZZS3_k127_5950210_15	365046.Rta_30490	8.395e-20	95.0	2EIHA@1|root,33C8N@2|Bacteria,1NG9G@1224|Proteobacteria,2VXQQ@28216|Betaproteobacteria,4AFRS@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5950210_12	365046.Rta_30500	4.755e-59	204.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,4ACIE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
ZZS3_k127_5952523_0	365046.Rta_37530	0.0	1306.0	COG0550@1|root,COG5531@1|root,COG0550@2|Bacteria,COG5531@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,4AAE2@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA topoisomerase, type IA, central domain protein	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
ZZS3_k127_5952523_7	398578.Daci_2914	2.058e-21	98.0	COG0671@1|root,COG0671@2|Bacteria,1Q03Y@1224|Proteobacteria,2W4SC@28216|Betaproteobacteria,4AIH6@80864|Comamonadaceae	28216|Betaproteobacteria	I	Protein of unknown function (DUF3703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3703
ZZS3_k127_5952523_5	338969.Rfer_3962	6.691e-76	257.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VQJB@28216|Betaproteobacteria,4ADKT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
ZZS3_k127_5952523_1	296591.Bpro_4702	1.253e-227	725.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VK5V@28216|Betaproteobacteria,4AAPR@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
ZZS3_k127_5952523_4	391735.Veis_0108	1.215e-110	363.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,4AAN2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
ZZS3_k127_5952523_3	296591.Bpro_4700	5.424e-202	635.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4AD0R@80864|Comamonadaceae	28216|Betaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
ZZS3_k127_5952523_6	1504672.669785206	3.582e-44	180.0	COG0454@1|root,COG0456@2|Bacteria,1QU9D@1224|Proteobacteria,2VUVY@28216|Betaproteobacteria,4AJK4@80864|Comamonadaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS3_k127_5952523_2	365046.Rta_37590	4.202e-217	676.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2WFJM@28216|Betaproteobacteria,4AD19@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
ZZS3_k127_5952779_3	365046.Rta_04440	8.707e-202	656.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,4AAYQ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.3.8.7,1.5.5.2	ko:K00249,ko:K00294,ko:K13821	ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051	RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
ZZS3_k127_5952779_11	614083.AWQR01000054_gene1932	1.453e-81	273.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQBV@28216|Betaproteobacteria,4ADGR@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
ZZS3_k127_5952779_14	614083.AWQR01000054_gene1933	2.169e-49	183.0	29DIQ@1|root,300GG@2|Bacteria,1RJVY@1224|Proteobacteria,2VTHH@28216|Betaproteobacteria,4AEF9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
ZZS3_k127_5952779_10	365046.Rta_04720	3.001e-104	344.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,4AAAV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
ZZS3_k127_5952779_2	365046.Rta_04730	2.987e-211	658.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,4ACKU@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
ZZS3_k127_5952779_1	365046.Rta_04740	1.081e-226	704.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,4AB13@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS3_k127_5952779_5	365046.Rta_04750	1.944e-152	486.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VHAW@28216|Betaproteobacteria,4ABEZ@80864|Comamonadaceae	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase, NAD-binding	glxR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_5952779_12	397945.Aave_0632	5.971e-69	253.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,4ADXY@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS3_k127_5952779_8	365046.Rta_04800	2.072e-111	366.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,4ABNW@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
ZZS3_k127_5952779_13	365046.Rta_04970	8.249e-51	183.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,4AEHJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
ZZS3_k127_5952779_7	365046.Rta_04980	4.141e-119	389.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,4AA8X@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
ZZS3_k127_5952779_0	365046.Rta_04990	0.0	1011.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,4AAF6@80864|Comamonadaceae	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
ZZS3_k127_5952779_4	397945.Aave_4469	1.014e-191	605.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,4AAZY@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
ZZS3_k127_5952779_9	365046.Rta_05010	2.945e-111	373.0	COG0457@1|root,COG4976@1|root,COG0457@2|Bacteria,COG4976@2|Bacteria,1RAIT@1224|Proteobacteria,2WEY2@28216|Betaproteobacteria,4AJ0V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TPR_1,TPR_16,TPR_2,TPR_8
ZZS3_k127_5952779_6	535289.Dtpsy_3131	4.506e-136	436.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,4AACZ@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_5955121_1	296591.Bpro_3279	4.935e-294	916.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,4AB7E@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS3_k127_5955121_9	543728.Vapar_3529	8.007e-50	205.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria,4AEC0@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM nitrite reductase NAD(P)H , small subunit	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
ZZS3_k127_5955121_0	296591.Bpro_3276	0.0	1495.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,4AA8E@80864|Comamonadaceae	28216|Betaproteobacteria	C	nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein	nirB	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
ZZS3_k127_5955121_3	595537.Varpa_4041	1.089e-197	648.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,4AAPE@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Major facilitator superfamily	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
ZZS3_k127_5955121_5	1286631.X805_40010	1.012e-88	334.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VSMR@28216|Betaproteobacteria,1KJB1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,PilJ
ZZS3_k127_5955121_7	365044.Pnap_1692	6.009e-65	224.0	COG1406@1|root,COG1406@2|Bacteria,1R99A@1224|Proteobacteria,2VMW9@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
ZZS3_k127_5955121_8	296591.Bpro_3271	1.947e-50	184.0	COG2201@1|root,COG2201@2|Bacteria,1N3V6@1224|Proteobacteria,2VSF3@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ZZS3_k127_5955121_2	365044.Pnap_1694	5.76e-281	879.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4AIA8@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,HAMP,HATPase_c,Hpt,PilJ
ZZS3_k127_5955121_4	305700.B447_16652	1.212e-140	453.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VJXH@28216|Betaproteobacteria,2KU9N@206389|Rhodocyclales	206389|Rhodocyclales	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	nasD	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
ZZS3_k127_5955121_6	1458275.AZ34_13070	2.556e-84	280.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2VH12@28216|Betaproteobacteria,4AB2S@80864|Comamonadaceae	28216|Betaproteobacteria	P	Nitrate ABC transporter inner membrane subunit	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
ZZS3_k127_6039721_2	365046.Rta_10030	2.201e-129	417.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2VMG6@28216|Betaproteobacteria,4ABN6@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_6039721_3	1504672.669785355	7.226e-99	334.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2VM56@28216|Betaproteobacteria,4ADEK@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
ZZS3_k127_6039721_1	420662.Mpe_A0755	1.624e-169	556.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2VH58@28216|Betaproteobacteria,1KJTY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C
ZZS3_k127_6039721_4	420662.Mpe_A0754	4.592e-83	283.0	COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,2VQDM@28216|Betaproteobacteria,1KPAF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_6039721_0	983917.RGE_26690	2.066e-182	593.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VGZY@28216|Betaproteobacteria,1KJDE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
ZZS3_k127_6040658_3	365046.Rta_02060	1.053e-217	678.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,4AA3J@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
ZZS3_k127_6040658_27	1129374.AJE_05416	1.87e-45	169.0	COG3832@1|root,COG3832@2|Bacteria,1RJUH@1224|Proteobacteria,1SG0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_6040658_21	1218075.BAYA01000010_gene3419	1.651e-89	298.0	COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2VKY2@28216|Betaproteobacteria,1K6GI@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
ZZS3_k127_6040658_13	296591.Bpro_0517	4.756e-132	428.0	COG0583@1|root,COG0583@2|Bacteria,1MWUD@1224|Proteobacteria,2VN7X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6040658_25	1123073.KB899242_gene1133	4.948e-55	198.0	COG3797@1|root,COG3797@2|Bacteria,1PC2B@1224|Proteobacteria,1TDEU@1236|Gammaproteobacteria,1XAMB@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
ZZS3_k127_6040658_15	365046.Rta_02050	1.946e-124	403.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,4AHNN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
ZZS3_k127_6040658_23	365046.Rta_02040	1.478e-78	267.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,4ADQ7@80864|Comamonadaceae	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
ZZS3_k127_6040658_7	365046.Rta_02030	6.171e-181	617.0	COG0477@1|root,COG0477@2|Bacteria,1R9KU@1224|Proteobacteria,2WHKD@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_6040658_0	365046.Rta_02020	0.0	1681.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,4A9PS@80864|Comamonadaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS3_k127_6040658_28	365046.Rta_33850	1.235e-30	123.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,2VVXU@28216|Betaproteobacteria,4AFCI@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
ZZS3_k127_6040658_12	296591.Bpro_4616	4.967e-148	471.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria,4ACAT@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
ZZS3_k127_6040658_14	365046.Rta_01980	2.199e-129	435.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria,4ABDN@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_6040658_4	882378.RBRH_02841	1.299e-207	682.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VJ3Z@28216|Betaproteobacteria,1KIFW@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
ZZS3_k127_6040658_9	94624.Bpet4569	1.399e-159	520.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM multicopper oxidase type	sufI	-	1.3.3.5	ko:K04753,ko:K08100,ko:K14588	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_6040658_16	365046.Rta_01970	2.49e-122	398.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,4ABX0@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_6040658_5	1223521.BBJX01000002_gene2871	9.333e-192	612.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2WGIZ@28216|Betaproteobacteria,4A9M2@80864|Comamonadaceae	28216|Betaproteobacteria	G	Major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
ZZS3_k127_6040658_17	381666.H16_A2807	1.03e-119	400.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,1K465@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_6040658_18	365046.Rta_01950	4.339e-116	402.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,2VM6W@28216|Betaproteobacteria,4AAMQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	ompR2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_6040658_8	365046.Rta_01940	6.005e-174	556.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria,4AAB3@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ZZS3_k127_6040658_11	1276756.AUEX01000002_gene566	1.044e-158	506.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2VMRK@28216|Betaproteobacteria,4AD1J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
ZZS3_k127_6040658_10	365046.Rta_01890	2.365e-159	507.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,4ACYJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS3_k127_6040658_29	1123504.JQKD01000035_gene2699	2.075e-26	122.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,4AFCT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
ZZS3_k127_6040658_6	358220.C380_01505	1.241e-188	594.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,4A9UB@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS3_k127_6040658_26	365044.Pnap_0140	1.89e-49	198.0	2ASHY@1|root,31HYC@2|Bacteria,1RIM4@1224|Proteobacteria,2VSD6@28216|Betaproteobacteria,4AEK4@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6040658_2	365046.Rta_01840	6.288e-253	801.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,4AB9M@80864|Comamonadaceae	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
ZZS3_k127_6040658_19	257310.BB0712	2.479e-108	359.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2W919@28216|Betaproteobacteria,3T7MH@506|Alcaligenaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6040658_1	1123504.JQKD01000014_gene870	3.177e-297	918.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VN4I@28216|Betaproteobacteria,4AC7B@80864|Comamonadaceae	28216|Betaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
ZZS3_k127_6040658_20	257310.BB0733	7.724e-100	341.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6040658_24	1157708.KB907466_gene655	6.452e-67	234.0	COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,2VSV9@28216|Betaproteobacteria,4AERH@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM homoprotocatechuate degradation operon regulator, HpaR	hpaR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_6040658_22	543728.Vapar_0245	1.264e-82	279.0	COG0179@1|root,COG0179@2|Bacteria,1R51B@1224|Proteobacteria,2VSKH@28216|Betaproteobacteria,4ADM6@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.1.1.68	ko:K05921	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04134,R04380	RC01085,RC02669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_6042468_0	365044.Pnap_1359	5.866e-288	894.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,4A9P0@80864|Comamonadaceae	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
ZZS3_k127_6042468_1	365046.Rta_26870	1.754e-144	490.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria,4AB2Z@80864|Comamonadaceae	28216|Betaproteobacteria	O	20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
ZZS3_k127_6042468_2	365046.Rta_26880	6.019e-143	456.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,2VHIU@28216|Betaproteobacteria,4AAC7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
ZZS3_k127_6042468_3	365046.Rta_26900	7.948e-137	439.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,4AAXZ@80864|Comamonadaceae	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
ZZS3_k127_6042468_6	614083.AWQR01000055_gene1971	3.464e-29	128.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,4AJVP@80864|Comamonadaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_6042468_5	614083.AWQR01000055_gene1968	5.249e-52	193.0	COG5395@1|root,COG5395@2|Bacteria,1N0CF@1224|Proteobacteria,2VSEW@28216|Betaproteobacteria,4AENA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
ZZS3_k127_6042468_7	1268622.AVS7_01300	8.37e-27	114.0	2DNMK@1|root,32Y4Z@2|Bacteria,1NETN@1224|Proteobacteria,2VW6U@28216|Betaproteobacteria,4AFM4@80864|Comamonadaceae	28216|Betaproteobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
ZZS3_k127_6042468_4	1458275.AZ34_02835	8.126e-129	421.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria,4ABP5@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
ZZS3_k127_6042468_8	887062.HGR_16235	1.062e-24	118.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria,4ABEC@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator	lytT	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
ZZS3_k127_6052952_5	595537.Varpa_1318	1.234e-82	287.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VRRS@28216|Betaproteobacteria,4ADPH@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
ZZS3_k127_6052952_3	365046.Rta_18550	2.759e-125	412.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,4AATB@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
ZZS3_k127_6052952_6	543728.Vapar_5992	3.871e-78	267.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
ZZS3_k127_6052952_8	365046.Rta_17090	3.026e-54	201.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_6052952_4	1286631.X805_20350	2.019e-90	316.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,1KJDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
ZZS3_k127_6052952_1	690585.JNNU01000004_gene4053	6.271e-178	562.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,4BDWB@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
ZZS3_k127_6052952_7	365046.Rta_17090	4.039e-56	211.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_6052952_2	1157708.KB907451_gene4842	2.775e-130	434.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2VP0H@28216|Betaproteobacteria,4AC46@80864|Comamonadaceae	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
ZZS3_k127_6052952_0	365046.Rta_18590	9.912e-189	595.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2VIKG@28216|Betaproteobacteria,4AC8S@80864|Comamonadaceae	28216|Betaproteobacteria	S	Fad dependent oxidoreductase	lhgO	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_6057732_0	1276756.AUEX01000001_gene933	3.016e-202	634.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,4A9KW@80864|Comamonadaceae	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
ZZS3_k127_6057732_3	365046.Rta_31450	1.022e-141	456.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2VK9F@28216|Betaproteobacteria,4AG8F@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_6057732_2	543728.Vapar_1299	9.555e-143	457.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,4A9RN@80864|Comamonadaceae	28216|Betaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS3_k127_6057732_5	365046.Rta_31470	1.561e-36	140.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,4AEUE@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	sirA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
ZZS3_k127_6057732_4	365046.Rta_31480	8.506e-93	310.0	COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria,2VRF4@28216|Betaproteobacteria,4ADHV@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
ZZS3_k127_6057732_1	365046.Rta_31490	1.34e-182	575.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,4AC80@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_6057732_6	319225.Plut_1886	1.056e-15	81.0	COG0472@1|root,COG0472@2|Bacteria,1FF74@1090|Chlorobi	1090|Chlorobi	M	Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
ZZS3_k127_6091855_1	1504672.669784444	5.108e-212	683.0	COG2885@1|root,COG4719@1|root,COG2885@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria	1224|Proteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
ZZS3_k127_6091855_5	1504672.669784445	1.237e-58	226.0	COG4719@1|root,COG4719@2|Bacteria,1R87U@1224|Proteobacteria	1224|Proteobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS3_k127_6091855_6	1504672.669784446	5.325e-54	195.0	COG4719@1|root,COG4719@2|Bacteria,1N09K@1224|Proteobacteria	1224|Proteobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS3_k127_6091855_4	1504672.669784447	1.175e-67	243.0	COG4719@1|root,COG4719@2|Bacteria,1RARY@1224|Proteobacteria	1224|Proteobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
ZZS3_k127_6091855_0	365046.Rta_28850	1.378e-224	702.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VH77@28216|Betaproteobacteria,4AAT7@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	lldD	-	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
ZZS3_k127_6091855_2	365046.Rta_28870	3.617e-204	648.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VJNS@28216|Betaproteobacteria,4A9Z0@80864|Comamonadaceae	28216|Betaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
ZZS3_k127_6091855_3	864073.HFRIS_018257	5.531e-148	474.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,47299@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30,5.4.2.9	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	-	R00409,R00661	RC00286,RC00287,RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
ZZS3_k127_6091855_8	365046.Rta_28910	4.207e-32	130.0	2EIWR@1|root,33CN2@2|Bacteria,1NI5Y@1224|Proteobacteria,2VYR5@28216|Betaproteobacteria,4AIBR@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6091855_7	596153.Alide_3199	9.238e-40	147.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,4AA88@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
ZZS3_k127_6096020_5	365046.Rta_19100	5.5e-47	169.0	COG0329@1|root,COG0329@2|Bacteria,1MUNF@1224|Proteobacteria,2VH4S@28216|Betaproteobacteria,4ABAP@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
ZZS3_k127_6096020_2	420662.Mpe_A0971	4.951e-96	325.0	COG2186@1|root,COG2186@2|Bacteria,1R68P@1224|Proteobacteria,2VK2A@28216|Betaproteobacteria,1KK7R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
ZZS3_k127_6096020_1	395495.Lcho_1115	1.015e-127	413.0	COG0451@1|root,COG0451@2|Bacteria,1MWVE@1224|Proteobacteria,2VI2W@28216|Betaproteobacteria,1KK81@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	Male sterility protein	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
ZZS3_k127_6096020_0	614083.AWQR01000002_gene2966	1.006e-148	492.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VKC6@28216|Betaproteobacteria,4AC8C@80864|Comamonadaceae	28216|Betaproteobacteria	G	TRAP dicarboxylate transporter	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
ZZS3_k127_6096020_4	1504672.669786680	2.09e-62	221.0	COG3090@1|root,COG3090@2|Bacteria,1R417@1224|Proteobacteria	1224|Proteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctQ	dctQ	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_6096020_3	395495.Lcho_1112	5.277e-91	301.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,1KKIQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K11690,ko:K21393	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
ZZS3_k127_6160899_1	420324.KI912082_gene6957	4.161e-224	705.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,1JUZ2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
ZZS3_k127_6160899_5	395492.Rleg2_5184	3.403e-87	296.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria,2U0JF@28211|Alphaproteobacteria,4B84Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_6160899_9	1297570.MESS4_790088	1.95e-40	155.0	COG4566@1|root,COG4566@2|Bacteria,1N460@1224|Proteobacteria,2UD2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_6160899_6	1380391.JIAS01000012_gene4071	8.568e-84	319.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,2JQYF@204441|Rhodospirillales	204441|Rhodospirillales	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
ZZS3_k127_6160899_8	1267535.KB906767_gene1910	6.912e-44	164.0	COG4566@1|root,COG4566@2|Bacteria,3Y58V@57723|Acidobacteria,2JJQJ@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_6160899_0	1380355.JNIJ01000030_gene5643	0.0	2210.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQX3@28211|Alphaproteobacteria,3JR5W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_9,Pkinase
ZZS3_k127_6160899_4	1287116.X734_23605	9.519e-116	410.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
ZZS3_k127_6160899_3	864051.BurJ1DRAFT_0217	2.508e-138	447.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VJFU@28216|Betaproteobacteria,1KK9G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
ZZS3_k127_6160899_2	365044.Pnap_2604	3.446e-146	469.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VJ3R@28216|Betaproteobacteria,4ABTD@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10553	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	BPD_transp_2
ZZS3_k127_6160899_7	319795.Dgeo_2855	2.826e-51	200.0	COG1129@1|root,COG1129@2|Bacteria,1WM1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K10554	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	ABC_tran
ZZS3_k127_6170034_6	266265.Bxe_C0728	2.468e-88	295.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,1K9E8@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Amidohydrolase family	trzA	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_6170034_5	397945.Aave_0200	1.994e-90	318.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AAJP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6170034_3	266265.Bxe_C0729	5.078e-113	397.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VN08@28216|Betaproteobacteria,1K4UP@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_6170034_2	1038858.AXBA01000005_gene4457	2.639e-124	426.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TUG1@28211|Alphaproteobacteria,3F26P@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ZZS3_k127_6170034_0	365046.Rta_37800	9.634e-270	833.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,4A9UX@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
ZZS3_k127_6170034_4	365046.Rta_37790	1.381e-110	367.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,4AAH6@80864|Comamonadaceae	28216|Betaproteobacteria	JM	Nucleotidyl transferase	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
ZZS3_k127_6170034_7	365046.Rta_37780	5.894e-44	164.0	COG1586@1|root,COG1586@2|Bacteria,1QWFT@1224|Proteobacteria,2VTEG@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	2.5.1.16,4.1.1.50	ko:K00797,ko:K01611	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
ZZS3_k127_6170034_1	365046.Rta_37770	9.172e-249	773.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,4AB6C@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the transketolase family	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
ZZS3_k127_6176135_6	1532557.JL37_18570	2.686e-33	131.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VN4I@28216|Betaproteobacteria,3T6WQ@506|Alcaligenaceae	28216|Betaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
ZZS3_k127_6176135_2	1532557.JL37_18575	5.218e-120	392.0	COG0583@1|root,COG0583@2|Bacteria,1P2I1@1224|Proteobacteria,2VT4T@28216|Betaproteobacteria,3T4U4@506|Alcaligenaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6176135_3	296591.Bpro_3692	4.684e-119	389.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2VKV6@28216|Betaproteobacteria,4AD8I@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_6176135_4	398578.Daci_0949	8.324e-95	326.0	COG0662@1|root,COG0662@2|Bacteria,1P536@1224|Proteobacteria,2VK28@28216|Betaproteobacteria,4AATE@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_6176135_5	296591.Bpro_3690	3.293e-83	284.0	COG2267@1|root,COG2267@2|Bacteria,1R9YW@1224|Proteobacteria,2VQEP@28216|Betaproteobacteria,4ADN1@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_6176135_1	296591.Bpro_3689	3.552e-125	410.0	COG1414@1|root,COG1414@2|Bacteria,1MYZS@1224|Proteobacteria,2VJY8@28216|Betaproteobacteria,4ACR8@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_6176135_0	296591.Bpro_3688	3.651e-130	421.0	COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2VNXU@28216|Betaproteobacteria,4ACAY@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS3_k127_620485_3	358220.C380_07465	1.496e-193	606.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,4AAWB@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
ZZS3_k127_620485_8	614083.AWQR01000010_gene1566	2.415e-09	60.0	2EH8N@1|root,33B0H@2|Bacteria	2|Bacteria	S	Entericidin EcnA/B family	-	-	-	-	-	-	-	-	-	-	-	-	Entericidin
ZZS3_k127_620485_5	1276756.AUEX01000014_gene2905	8.802e-131	418.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,4AA66@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
ZZS3_k127_620485_2	365046.Rta_28170	4.485e-206	647.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,4AAYY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS3_k127_620485_1	365046.Rta_28180	3.934e-229	712.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,4AAJE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS3_k127_620485_0	365046.Rta_28190	4.678e-247	794.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,4ACIR@80864|Comamonadaceae	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
ZZS3_k127_620485_4	365046.Rta_28200	4.037e-137	450.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,4AA8B@80864|Comamonadaceae	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
ZZS3_k127_620485_6	296591.Bpro_3615	2.95e-95	317.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,4A9WC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
ZZS3_k127_620485_7	887062.HGR_06101	4.02e-45	165.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,4A9QY@80864|Comamonadaceae	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_6232839_2	1123504.JQKD01000023_gene193	1.389e-103	340.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,4AA4F@80864|Comamonadaceae	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ZZS3_k127_6232839_0	365046.Rta_26460	4.525e-182	574.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VHCB@28216|Betaproteobacteria,4AA8K@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_6232839_1	365046.Rta_26450	1.647e-121	413.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,4ABH1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
ZZS3_k127_6232839_6	365046.Rta_26440	1.277e-45	168.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,4AEHQ@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
ZZS3_k127_6232839_5	595537.Varpa_4025	3.071e-64	223.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,4AE1G@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
ZZS3_k127_6232839_3	365046.Rta_26420	3.549e-101	330.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,4ACEJ@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
ZZS3_k127_6232839_4	365046.Rta_26410	2.018e-97	329.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,4ABHW@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
ZZS3_k127_6240241_0	358220.C380_02070	0.0	1072.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAP6@80864|Comamonadaceae	28216|Betaproteobacteria	V	Transporter, hydrophobe amphiphile efflux-1 (HAE1) family	acrB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_6240241_2	1504672.669783465	6.306e-150	516.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,4AADJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
ZZS3_k127_6240241_7	365046.Rta_20760	5.306e-21	96.0	295M6@1|root,2ZSYK@2|Bacteria,1P4BV@1224|Proteobacteria,2W56M@28216|Betaproteobacteria,4AII3@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6240241_6	358220.C380_20050	2.38e-94	316.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria,2VJFB@28216|Betaproteobacteria,4AC4F@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_6240241_5	1121106.JQKB01000014_gene5682	2.136e-101	358.0	COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2TRSQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_6240241_4	257310.BB4372	2.092e-109	366.0	COG0477@1|root,COG2814@2|Bacteria,1PE5A@1224|Proteobacteria,2VHTJ@28216|Betaproteobacteria,3T1CE@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Permeases of the major facilitator superfamily	emrB_1	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS3_k127_6240241_3	365044.Pnap_2949	1.218e-114	393.0	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2VKPD@28216|Betaproteobacteria,4ACDS@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_6240241_1	257310.BB2422	1.089e-164	525.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,3T5PE@506|Alcaligenaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ZZS3_k127_6280975_7	365046.Rta_30920	6.464e-93	319.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria,4AD9X@80864|Comamonadaceae	28216|Betaproteobacteria	L	DEAD H associated domain protein	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
ZZS3_k127_6280975_9	365046.Rta_30930	6.715e-62	223.0	COG1846@1|root,COG1846@2|Bacteria,1N5CQ@1224|Proteobacteria,2VT0D@28216|Betaproteobacteria,4AF4J@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_6280975_5	1123504.JQKD01000016_gene1975	7.126e-146	468.0	COG3181@1|root,COG3181@2|Bacteria,1R43T@1224|Proteobacteria,2VHTA@28216|Betaproteobacteria,4ACZZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6280975_6	365046.Rta_30960	1.407e-142	459.0	COG3181@1|root,COG3181@2|Bacteria,1Q9QH@1224|Proteobacteria,2VNFZ@28216|Betaproteobacteria,4ACBX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6280975_0	365046.Rta_30970	9.125e-262	827.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2WEXA@28216|Betaproteobacteria,4A9KB@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
ZZS3_k127_6280975_1	365046.Rta_31000	1.025e-261	815.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,4AAM2@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ZZS3_k127_6280975_3	1223521.BBJX01000013_gene419	1.547e-180	576.0	COG0683@1|root,COG0683@2|Bacteria,1R9B2@1224|Proteobacteria,2VIJ4@28216|Betaproteobacteria,4AE1Z@80864|Comamonadaceae	28216|Betaproteobacteria	E	Amino acid amide ABC transporter substrate-binding protein, HAAT family	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_6280975_2	1223521.BBJX01000020_gene2943	5.252e-228	716.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,4AAWF@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_6280975_4	365046.Rta_00450	4.973e-165	531.0	COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2VH2Z@28216|Betaproteobacteria,4ABSN@80864|Comamonadaceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS3_k127_6280975_11	405948.SACE_3736	1.428e-11	73.0	2E8C8@1|root,332QW@2|Bacteria,2GVKT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6280975_10	85643.Tmz1t_2757	7.654e-45	165.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,2KX0T@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
ZZS3_k127_6280975_8	365046.Rta_31040	1.616e-83	279.0	2DBFU@1|root,2Z90B@2|Bacteria,1PI0M@1224|Proteobacteria,2WGPR@28216|Betaproteobacteria,4A9V4@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
ZZS3_k127_6291121_1	1268622.AVS7_00017	3.327e-121	396.0	COG0491@1|root,COG0491@2|Bacteria,1NCIF@1224|Proteobacteria,2VJVR@28216|Betaproteobacteria,4ABYD@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_6291121_0	365046.Rta_05450	9.735e-315	970.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,4AB4Z@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_6291121_5	358220.C380_21040	1.177e-76	265.0	2AYXV@1|root,31R3M@2|Bacteria,1RHPG@1224|Proteobacteria,2VS4A@28216|Betaproteobacteria,4ADQE@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6291121_4	365046.Rta_05460	2.41e-90	319.0	COG1075@1|root,COG1075@2|Bacteria,1R75P@1224|Proteobacteria,2VU4P@28216|Betaproteobacteria,4ADQ9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,PGAP1
ZZS3_k127_6291121_6	365046.Rta_05470	5.919e-56	203.0	COG2197@1|root,COG2197@2|Bacteria,1N324@1224|Proteobacteria,2VUTR@28216|Betaproteobacteria,4AFBR@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ZZS3_k127_6291121_3	365046.Rta_05480	3.246e-92	309.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VRBJ@28216|Betaproteobacteria,4AEED@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_6291121_2	296591.Bpro_4216	9.231e-93	322.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2W2GN@28216|Betaproteobacteria,4AHRN@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6358986_5	864051.BurJ1DRAFT_0727	4.509e-128	417.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,1KMYK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6358986_1	1265502.KB905948_gene1024	2.548e-193	609.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2VIVU@28216|Betaproteobacteria,4A9N6@80864|Comamonadaceae	28216|Betaproteobacteria	CH	4-hydroxybenzoate 3-monooxygenase	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_6358986_6	365046.Rta_20530	1.768e-124	402.0	COG1414@1|root,COG1414@2|Bacteria,1R5WX@1224|Proteobacteria,2WEVX@28216|Betaproteobacteria,4AAD3@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	pcaU	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
ZZS3_k127_6358986_7	365046.Rta_20520	1.902e-118	383.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,4AB4I@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	lsfA	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
ZZS3_k127_6358986_2	365046.Rta_20510	5.433e-179	563.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,4A9S5@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
ZZS3_k127_6358986_4	365046.Rta_20500	4.297e-157	498.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,4AAIF@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sulfate ABC transporter inner membrane subunit CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
ZZS3_k127_6358986_3	365046.Rta_20490	2.867e-157	529.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,4AAQM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sulfate ABC transporter, inner membrane subunit CysW	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
ZZS3_k127_6358986_0	296591.Bpro_2379	2.151e-205	643.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,4AC3N@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
ZZS3_k127_6358986_8	296591.Bpro_2385	2.223e-74	272.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,4ADX3@80864|Comamonadaceae	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
ZZS3_k127_6396277_2	296591.Bpro_2800	3.05e-188	593.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	4.1.1.8	ko:K01577	ko00630,ko01100,map00630,map01100	-	R01908	RC00620	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_6396277_1	1458275.AZ34_11065	2.652e-243	755.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMNC@28216|Betaproteobacteria,4AD5V@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate	frc	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_6396277_0	1411123.JQNH01000001_gene2121	0.0	1148.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TQYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	MA20_15065	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
ZZS3_k127_6396277_3	296591.Bpro_2804	2.345e-108	358.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,4AB8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
ZZS3_k127_6400433_1	365046.Rta_15340	9.547e-122	400.0	COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,2WGNF@28216|Betaproteobacteria,4AJWI@80864|Comamonadaceae	28216|Betaproteobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
ZZS3_k127_6400433_2	543728.Vapar_3095	1.036e-99	344.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,4ACNB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
ZZS3_k127_6400433_3	365046.Rta_15360	5.556e-96	337.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,4AC0H@80864|Comamonadaceae	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_6400433_4	397945.Aave_2316	1.42e-83	279.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,4AA9Y@80864|Comamonadaceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS3_k127_6400433_7	365044.Pnap_2895	4.971e-69	250.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
ZZS3_k127_6400433_5	365046.Rta_15390	1.113e-80	274.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,4AB2J@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
ZZS3_k127_6400433_0	365046.Rta_15400	2.695e-262	813.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,4ABUH@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
ZZS3_k127_6400433_6	1458275.AZ34_07435	6.319e-74	272.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,4AANM@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM HhH-GPD family protein	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS3_k127_6418510_5	1458357.BG58_08750	9.348e-106	352.0	COG4857@1|root,COG4857@2|Bacteria,1PNY2@1224|Proteobacteria,2VQ33@28216|Betaproteobacteria,1K24Y@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
ZZS3_k127_6418510_1	296591.Bpro_2929	2.715e-144	464.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,4AA9N@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
ZZS3_k127_6418510_0	1100720.ALKN01000033_gene744	1.385e-150	496.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VM5J@28216|Betaproteobacteria,4AD2W@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	drug resistance transporter, Bcr CflA subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
ZZS3_k127_6418510_2	1123504.JQKD01000016_gene1872	1.279e-121	400.0	COG3568@1|root,COG3568@2|Bacteria,1R99W@1224|Proteobacteria,2VPVB@28216|Betaproteobacteria,4ADBE@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS3_k127_6418510_8	1366050.N234_36675	2.991e-10	70.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32
ZZS3_k127_6418510_6	1367847.JCM7686_2727	2.125e-77	277.0	COG1177@1|root,COG1177@2|Bacteria,1R4WA@1224|Proteobacteria,2TTY8@28211|Alphaproteobacteria,2PXE1@265|Paracoccus	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
ZZS3_k127_6418510_7	314270.RB2083_837	3.612e-75	263.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2TTJ6@28211|Alphaproteobacteria,3ZGDX@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	P	transport system permease component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
ZZS3_k127_6418510_4	392499.Swit_2521	6.515e-109	361.0	COG4638@1|root,COG4638@2|Bacteria,1NWEN@1224|Proteobacteria,2US5P@28211|Alphaproteobacteria,2KA8Y@204457|Sphingomonadales	204457|Sphingomonadales	P	PFAM Rieske 2Fe-2S domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS3_k127_6418510_3	246200.SPOA0382	2.579e-112	372.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4ND68@97050|Ruegeria	28211|Alphaproteobacteria	E	TOBE domain	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
ZZS3_k127_6444575_3	365046.Rta_29090	2.202e-107	368.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,4A9JB@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
ZZS3_k127_6444575_0	596153.Alide_0928	2.168e-207	648.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,4AA8G@80864|Comamonadaceae	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
ZZS3_k127_6444575_5	365046.Rta_29110	3.919e-44	161.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,4AEWJ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
ZZS3_k127_6444575_4	365046.Rta_29120	5.19e-48	189.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,4AECN@80864|Comamonadaceae	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
ZZS3_k127_6444575_2	365046.Rta_29130	2.322e-147	486.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,4A9VJ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS3_k127_6444575_1	365046.Rta_29140	7.519e-158	501.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AA1I@80864|Comamonadaceae	28216|Betaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS3_k127_6492515_8	365046.Rta_08960	2.306e-23	99.0	COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2VRFD@28216|Betaproteobacteria,4ADV8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_6492515_2	365046.Rta_08970	5.78e-155	520.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2VKG2@28216|Betaproteobacteria,4AJBI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	ybiC	-	-	ko:K13574	-	-	-	-	ko00000,ko01000	-	-	-	Ldh_2
ZZS3_k127_6492515_0	1504672.669784960	2.523e-301	930.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,4AB17@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	uxaA	-	4.2.1.7,4.4.1.24	ko:K01685,ko:K16846	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ZZS3_k127_6492515_4	1231185.BAMP01000056_gene4763	8.303e-108	365.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,43H3P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_6492515_6	365046.Rta_09000	1.318e-80	289.0	COG3090@1|root,COG3090@2|Bacteria,1R7TV@1224|Proteobacteria,2VPJP@28216|Betaproteobacteria,4ADJ5@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_6492515_1	365046.Rta_09010	2.327e-178	563.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2VME7@28216|Betaproteobacteria,4AASE@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_6492515_5	365046.Rta_09020	8.043e-106	349.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2VP3Y@28216|Betaproteobacteria,4ADV9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_6492515_3	365046.Rta_09030	5.441e-130	418.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2VJVQ@28216|Betaproteobacteria,4ABNS@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	ko:K18335	ko00051,ko01120,map00051,map01120	-	R10690	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
ZZS3_k127_6492515_7	595537.Varpa_0812	1.162e-76	277.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2VN5A@28216|Betaproteobacteria,4AC1W@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
ZZS3_k127_6492515_9	365046.Rta_09050	7.2e-13	68.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,4AA1T@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_6492665_2	266265.Bxe_C0728	1.348e-96	323.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,1K9E8@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Amidohydrolase family	trzA	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_6492665_3	1157708.KB907471_gene157	2.621e-50	189.0	COG1802@1|root,COG1802@2|Bacteria,1RJEX@1224|Proteobacteria,2W8YG@28216|Betaproteobacteria,4AI6W@80864|Comamonadaceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_6492665_4	977880.RALTA_A2548	1.958e-32	143.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2VIXF@28216|Betaproteobacteria,1KC9U@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
ZZS3_k127_6492665_0	85643.Tmz1t_1660	0.0	1696.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria,2KVIK@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
ZZS3_k127_6492665_1	365046.Rta_37850	4.833e-98	322.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,4AAXI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Phosphate acetyl butaryl transferase	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_DH,Malic_M,PTA_PTB,malic
ZZS3_k127_6495237_5	977880.RALTA_B1405	7.025e-75	259.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6495237_10	1123072.AUDH01000012_gene3515	1.402e-21	105.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2TQQI@28211|Alphaproteobacteria,2JZTI@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
ZZS3_k127_6495237_1	426355.Mrad2831_6198	8.613e-126	421.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,1JR1F@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox,Polysacc_deac_1
ZZS3_k127_6495237_3	477184.KYC_04577	3.958e-116	385.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6495237_0	1123060.JONP01000004_gene669	2.574e-126	417.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS3_k127_6495237_6	1532557.JL37_25360	1.25e-56	211.0	COG0583@1|root,COG0583@2|Bacteria,1R9M2@1224|Proteobacteria,2W32Y@28216|Betaproteobacteria	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6495237_4	448385.sce5373	3.451e-88	298.0	COG0702@1|root,COG0702@2|Bacteria,1MYVU@1224|Proteobacteria	1224|Proteobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
ZZS3_k127_6495237_9	595460.RRSWK_07188	3.894e-41	173.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,Peptidase_M9,Peptidase_M9_N
ZZS3_k127_6495237_2	1123504.JQKD01000006_gene1546	1.105e-120	400.0	COG1028@1|root,COG1028@2|Bacteria,1MWZE@1224|Proteobacteria,2VM9M@28216|Betaproteobacteria,4AGDM@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_6495237_7	1123504.JQKD01000006_gene1545	3.96e-43	164.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,2WEFC@28216|Betaproteobacteria	28216|Betaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
ZZS3_k127_6495237_8	365046.Rta_16820	9.418e-42	158.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2VS4H@28216|Betaproteobacteria,4ADYD@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_6518531_4	296591.Bpro_2795	1.773e-100	329.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,4AC49@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6518531_5	296591.Bpro_2796	1.176e-65	229.0	2BKYI@1|root,32FF5@2|Bacteria,1MY1A@1224|Proteobacteria,2VRUQ@28216|Betaproteobacteria,4AERJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
ZZS3_k127_6518531_0	296591.Bpro_2797	2.259e-291	899.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAW5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
ZZS3_k127_6518531_2	296591.Bpro_2798	5.456e-118	385.0	COG2823@1|root,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,2VK5B@28216|Betaproteobacteria,4AHC6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
ZZS3_k127_6518531_3	296591.Bpro_2799	1.662e-103	340.0	COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,4ACEI@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ZZS3_k127_6518531_1	864051.BurJ1DRAFT_3664	1.727e-127	413.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2W96R@28216|Betaproteobacteria,1KNUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_6550323_2	365046.Rta_22640	5.448e-84	280.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,4A9K7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2
ZZS3_k127_6550323_3	365046.Rta_22650	2.715e-61	216.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,4AEDX@80864|Comamonadaceae	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_10,Fer4_4
ZZS3_k127_6550323_0	1504672.669787028	4.987e-216	673.0	COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2VGZS@28216|Betaproteobacteria,4AB1B@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
ZZS3_k127_6550323_4	767029.HMPREF9154_2631	1.214e-14	85.0	COG1305@1|root,COG1305@2|Bacteria,2IB3E@201174|Actinobacteria	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ZZS3_k127_6550323_1	365046.Rta_22870	2.782e-92	311.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,4AB8H@80864|Comamonadaceae	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
ZZS3_k127_6570918_9	365046.Rta_18680	2.168e-57	200.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,4A9KI@80864|Comamonadaceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_6570918_5	365046.Rta_18690	3.638e-113	366.0	COG0638@1|root,COG0638@2|Bacteria,1QZDX@1224|Proteobacteria,2WHKN@28216|Betaproteobacteria,4AJZG@80864|Comamonadaceae	28216|Betaproteobacteria	O	Proteasome subunit	-	-	-	-	-	-	-	-	-	-	-	-	Proteasome
ZZS3_k127_6570918_0	365046.Rta_18700	2.519e-319	984.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,4AAQ4@80864|Comamonadaceae	28216|Betaproteobacteria	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_6570918_8	358220.C380_11590	6.699e-68	254.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,4ADQ3@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K13695,ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
ZZS3_k127_6570918_1	1123504.JQKD01000031_gene4539	7.463e-176	559.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,4AAI2@80864|Comamonadaceae	28216|Betaproteobacteria	G	glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
ZZS3_k127_6570918_6	365046.Rta_18730	5.321e-111	361.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VQAN@28216|Betaproteobacteria,4AF7J@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_6570918_2	365046.Rta_18740	9.341e-159	508.0	COG0745@1|root,COG4585@1|root,COG0745@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,4AANV@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_6570918_4	234267.Acid_4061	5.009e-118	389.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,Dala_Dala_lig_C,RimK
ZZS3_k127_6570918_7	296591.Bpro_2647	6.868e-79	268.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJPQ@28216|Betaproteobacteria,4AB00@80864|Comamonadaceae	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
ZZS3_k127_6570918_3	365046.Rta_18780	7.728e-122	395.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,4A9US@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS3_k127_6573954_1	296591.Bpro_1667	1.731e-210	661.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_6573954_5	365046.Rta_11030	1.122e-105	348.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,4AAHT@80864|Comamonadaceae	28216|Betaproteobacteria	O	Methyltransferase type 11	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
ZZS3_k127_6573954_6	1268622.AVS7_02288	1.703e-43	160.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria,4AEZQ@80864|Comamonadaceae	28216|Betaproteobacteria	P	SMART Rhodanese domain protein	pspE2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS3_k127_6573954_2	365046.Rta_11010	1.013e-187	599.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,4ABVD@80864|Comamonadaceae	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS3_k127_6573954_7	204773.HEAR2939	6.447e-16	92.0	2EB3M@1|root,3354C@2|Bacteria,1N9Z4@1224|Proteobacteria,2VW86@28216|Betaproteobacteria,474ZR@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6573954_3	365046.Rta_10980	1.119e-177	577.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,4A9ND@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
ZZS3_k127_6573954_4	365046.Rta_10970	1.562e-147	472.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,4ACVZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaC	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS3_k127_6573954_0	296591.Bpro_1639	7.768e-241	749.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,4ABAF@80864|Comamonadaceae	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_6627253_1	365046.Rta_15850	9.141e-115	375.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,4AAGV@80864|Comamonadaceae	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
ZZS3_k127_6627253_2	795666.MW7_2653	1.968e-71	261.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1K16H@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	cheD2	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH
ZZS3_k127_6627253_4	870187.Thini_1331	8.346e-63	248.0	28IG1@1|root,2Z8HJ@2|Bacteria,1N6BT@1224|Proteobacteria,1SS2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6627253_3	671143.DAMO_2428	1.006e-65	234.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406,ko:K17763	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	4HB_MCP_1,DUF1983,DUF3365,HAMP,HATPase_c,HBM,HisKA,MASE4,MCPsignal,PAS,Protoglobin,Response_reg,STAS
ZZS3_k127_6627253_5	1296415.JACC01000001_gene3573	1.183e-47	192.0	2DUKC@1|root,33R3H@2|Bacteria,4P0Z8@976|Bacteroidetes,1I85Z@117743|Flavobacteriia,2YKDG@290174|Aquimarina	976|Bacteroidetes	S	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
ZZS3_k127_6627253_6	1173022.Cri9333_1836	3.063e-22	112.0	COG0702@1|root,COG1018@1|root,COG1251@1|root,COG4362@1|root,COG5126@1|root,COG0702@2|Bacteria,COG1018@2|Bacteria,COG1251@2|Bacteria,COG4362@2|Bacteria,COG5126@2|Bacteria,1G49Z@1117|Cyanobacteria,1H9E7@1150|Oscillatoriales	1117|Cyanobacteria	C	Oxidoreductase FAD-binding domain	-	-	1.14.14.47	ko:K00491,ko:K21832	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	-	R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000	-	-	-	EF-hand_5,FAD_binding_6,FHA,Fer2,Fer2_BFD,NAD_binding_1,NO_synthase
ZZS3_k127_6627253_7	1244869.H261_09647	3.495e-18	89.0	COG2846@1|root,COG2846@2|Bacteria,1QUSY@1224|Proteobacteria,2US4J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
ZZS3_k127_6627253_0	365046.Rta_15830	4.522e-316	972.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,4AARZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
ZZS3_k127_6642976_2	1276756.AUEX01000029_gene2191	1.798e-146	466.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VMGK@28216|Betaproteobacteria,4ABH6@80864|Comamonadaceae	28216|Betaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_6642976_8	266265.Bxe_C0859	2.103e-50	181.0	COG1545@1|root,COG1545@2|Bacteria,1N7HH@1224|Proteobacteria,2VT0N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
ZZS3_k127_6642976_11	596153.Alide_2412	1.313e-36	156.0	2EIC5@1|root,348PQ@2|Bacteria,1P1MS@1224|Proteobacteria,2WG7S@28216|Betaproteobacteria,4AIJC@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6642976_10	266265.Bxe_C0858	6.573e-40	159.0	COG2030@1|root,COG2030@2|Bacteria,1NF0N@1224|Proteobacteria,2VWVK@28216|Betaproteobacteria	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
ZZS3_k127_6642976_3	266265.Bxe_C0857	1.957e-146	477.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,1K12G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	e1 component (alpha subunit)	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
ZZS3_k127_6642976_1	266265.Bxe_C0856	3.279e-170	561.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,1K5RY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
ZZS3_k127_6642976_6	1276756.AUEX01000029_gene2197	2.586e-128	437.0	COG1024@1|root,COG1024@2|Bacteria,1QA5H@1224|Proteobacteria,2VPBN@28216|Betaproteobacteria,4AE72@80864|Comamonadaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS3_k127_6642976_4	266265.Bxe_C0854	1.458e-140	458.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2VZVR@28216|Betaproteobacteria,1KDI4@119060|Burkholderiaceae	28216|Betaproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_6642976_0	266265.Bxe_C0853	8.18e-208	656.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VK5F@28216|Betaproteobacteria,1KCN4@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdV	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_6642976_7	257313.BP0641	1.326e-95	328.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2W085@28216|Betaproteobacteria,3T76N@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6642976_5	257310.BB4718	1.526e-135	442.0	COG1804@1|root,COG1804@2|Bacteria,1QNB4@1224|Proteobacteria,2VKAD@28216|Betaproteobacteria,3T5DA@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_6642976_9	1123072.AUDH01000001_gene2791	8.357e-42	158.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2JVCU@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_6643752_5	365046.Rta_09580	4.268e-101	331.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,4ABQ9@80864|Comamonadaceae	28216|Betaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
ZZS3_k127_6643752_7	228410.NE2261	7.783e-50	199.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,371NA@32003|Nitrosomonadales	28216|Betaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
ZZS3_k127_6643752_2	358220.C380_03700	1.614e-159	510.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,4A9J9@80864|Comamonadaceae	28216|Betaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
ZZS3_k127_6643752_6	365046.Rta_09600	6.442e-79	264.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,4ADKY@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
ZZS3_k127_6643752_3	365046.Rta_09610	2.37e-143	459.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,4A9RQ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
ZZS3_k127_6643752_8	365046.Rta_09620	2.659e-34	136.0	COG3116@1|root,COG3116@2|Bacteria,1N95M@1224|Proteobacteria,2VVTP@28216|Betaproteobacteria,4AEUR@80864|Comamonadaceae	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
ZZS3_k127_6643752_0	1100721.ALKO01000020_gene937	8.792e-291	907.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,4AA3W@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
ZZS3_k127_6643752_1	365046.Rta_09640	8.196e-222	726.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,4AA27@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_6643752_4	365046.Rta_09660	4.11e-118	408.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,4ABB4@80864|Comamonadaceae	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_6683311_2	365044.Pnap_3816	3.083e-138	446.0	COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2VKNP@28216|Betaproteobacteria,4AC79@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	ko:K13794	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6683311_0	762376.AXYL_05678	2.39e-269	833.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VJUW@28216|Betaproteobacteria,3T1PP@506|Alcaligenaceae	28216|Betaproteobacteria	C	required for the utilization of tricarballylate as a carbon and energy source by S. enterica	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
ZZS3_k127_6683311_1	296591.Bpro_0640	7.698e-191	601.0	COG1146@1|root,COG1146@2|Bacteria,1MU2I@1224|Proteobacteria,2VJHI@28216|Betaproteobacteria,4AB3V@80864|Comamonadaceae	28216|Betaproteobacteria	C	CitB domain protein	citB	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_6683311_5	365046.Rta_35540	2.702e-06	50.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VPM0@28216|Betaproteobacteria,4ACTH@80864|Comamonadaceae	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_6683311_3	1100721.ALKO01000017_gene1635	1.558e-132	425.0	COG1028@1|root,COG1028@2|Bacteria,1QWBB@1224|Proteobacteria,2W24M@28216|Betaproteobacteria,4AJ28@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_6683311_4	296591.Bpro_0638	1.696e-112	367.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VI23@28216|Betaproteobacteria,4ABS4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6685683_6	742159.HMPREF0004_2961	1.686e-63	224.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VKFS@28216|Betaproteobacteria,3T282@506|Alcaligenaceae	28216|Betaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
ZZS3_k127_6685683_7	983545.Glaag_2574	2.992e-54	206.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,467DT@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
ZZS3_k127_6685683_5	42565.FP66_08385	7.021e-106	363.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XI3D@135619|Oceanospirillales	135619|Oceanospirillales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
ZZS3_k127_6685683_0	365046.Rta_25370	7.068e-308	970.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,4AA8Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
ZZS3_k127_6685683_1	365046.Rta_25360	1.136e-280	879.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,4ABXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
ZZS3_k127_6685683_2	365046.Rta_25350	1.581e-183	596.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,4ABMC@80864|Comamonadaceae	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
ZZS3_k127_6685683_8	688245.CtCNB1_2916	1.292e-51	205.0	COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,2VRYZ@28216|Betaproteobacteria,4ADYE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6685683_4	365044.Pnap_1216	1.368e-143	477.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,4ABD9@80864|Comamonadaceae	28216|Betaproteobacteria	M	lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
ZZS3_k127_6685683_3	365046.Rta_25240	6.225e-179	568.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,4AAEA@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
ZZS3_k127_6702331_10	1100721.ALKO01000017_gene1694	6.742e-18	84.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,4AD65@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
ZZS3_k127_6702331_1	365046.Rta_34040	3.43e-255	799.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,4AC7K@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
ZZS3_k127_6702331_2	365046.Rta_34020	2.398e-218	686.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,4ACEX@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
ZZS3_k127_6702331_5	365046.Rta_34010	4.334e-76	265.0	COG2863@1|root,COG2863@2|Bacteria,1PFFQ@1224|Proteobacteria,2VXBF@28216|Betaproteobacteria,4AFPX@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_6702331_6	614083.AWQR01000035_gene3612	1.324e-70	266.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VMQN@28216|Betaproteobacteria,4ADD5@80864|Comamonadaceae	28216|Betaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
ZZS3_k127_6702331_4	1366050.N234_22770	3.377e-83	287.0	COG0583@1|root,COG0583@2|Bacteria,1R9MA@1224|Proteobacteria,2VPV0@28216|Betaproteobacteria,1K40W@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	gbpR_3	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6702331_0	388051.AUFE01000016_gene5798	7.879e-292	908.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VNPK@28216|Betaproteobacteria,1K19G@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS3_k127_6702331_3	264198.Reut_B3966	1.308e-140	456.0	COG3181@1|root,COG3181@2|Bacteria,1PBQE@1224|Proteobacteria,2VPQG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6702331_9	94624.Bpet1251	2.811e-35	143.0	COG2203@1|root,COG2203@2|Bacteria,1N2UA@1224|Proteobacteria,2VWU6@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
ZZS3_k127_6702331_8	596153.Alide_1353	3.789e-48	176.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2WG03@28216|Betaproteobacteria,4AJU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS3_k127_6702331_7	365046.Rta_25890	1.944e-50	183.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,4AF2I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_6753625_4	748247.AZKH_2102	4.07e-44	175.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VKFS@28216|Betaproteobacteria,2KVRQ@206389|Rhodocyclales	206389|Rhodocyclales	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
ZZS3_k127_6753625_1	292415.Tbd_1622	8.874e-112	381.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KTCY@119069|Hydrogenophilales	119069|Hydrogenophilales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
ZZS3_k127_6753625_6	883.DvMF_0304	1.2e-41	162.0	COG4564@1|root,COG4564@2|Bacteria,1RJP6@1224|Proteobacteria,43BM9@68525|delta/epsilon subdivisions,2X6ZF@28221|Deltaproteobacteria,2MBBC@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Cache, type 2	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
ZZS3_k127_6753625_2	204773.HEAR3088	3.283e-91	323.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4738N@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,TarH
ZZS3_k127_6753625_3	261292.Nit79A3_2711	7.966e-59	209.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,3734B@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	PFAM CheW-like protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS3_k127_6753625_0	398578.Daci_0655	7.548e-157	522.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,4A9N1@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	cheA	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
ZZS3_k127_6753625_7	400668.Mmwyl1_3298	1.314e-38	148.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1XK82@135619|Oceanospirillales	135619|Oceanospirillales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ZZS3_k127_6753625_5	395493.BegalDRAFT_2974	1.031e-41	169.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S364@1236|Gammaproteobacteria,463EC@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_6753625_8	870187.Thini_2708	2.377e-31	127.0	COG0515@1|root,COG0515@2|Bacteria,1QXK0@1224|Proteobacteria,1T3DE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	Pkinase,TIR_2
ZZS3_k127_6813400_4	296591.Bpro_0119	1.989e-75	254.0	COG1309@1|root,COG1309@2|Bacteria,1R7QZ@1224|Proteobacteria,2VNS3@28216|Betaproteobacteria,4AABG@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_6813400_2	365046.Rta_00950	8.752e-127	411.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,2VNP3@28216|Betaproteobacteria,4ACVX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4
ZZS3_k127_6813400_0	365046.Rta_00920	8.806e-230	717.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,2VI3I@28216|Betaproteobacteria,4A9VU@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM Xanthine uracil vitamin C permease	rutG	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
ZZS3_k127_6813400_5	338969.Rfer_0061	2.464e-64	224.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VRG7@28216|Betaproteobacteria,4ADXZ@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM thioesterase superfamily protein	-	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
ZZS3_k127_6813400_3	1223521.BBJX01000002_gene2761	1.082e-93	315.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,4AADB@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
ZZS3_k127_6813400_1	365046.Rta_00850	1.491e-194	611.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,4AAZB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	dld	-	1.1.2.4,1.1.5.12	ko:K00102,ko:K03777	ko00620,ko01120,map00620,map01120	-	R00197,R00704,R11591	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_6841024_26	520709.F985_03820	1.114e-49	181.0	COG1310@1|root,COG1310@2|Bacteria,1PJEY@1224|Proteobacteria,1RVWX@1236|Gammaproteobacteria,3NJR1@468|Moraxellaceae	1236|Gammaproteobacteria	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
ZZS3_k127_6841024_13	520709.F985_03821	5.931e-92	319.0	2E63W@1|root,330SX@2|Bacteria,1Q2C1@1224|Proteobacteria,1TMAF@1236|Gammaproteobacteria,3NMNE@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_11	318996.AXAZ01000068_gene5244	8.966e-110	374.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_8,Trans_reg_C
ZZS3_k127_6841024_27	1217714.F975_00618	3.023e-45	172.0	COG1917@1|root,COG1917@2|Bacteria,1RASA@1224|Proteobacteria,1T07I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_6841024_16	1095769.CAHF01000018_gene788	2.539e-84	288.0	COG1280@1|root,COG1280@2|Bacteria,1RCPV@1224|Proteobacteria,2VR23@28216|Betaproteobacteria	28216|Betaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
ZZS3_k127_6841024_28	1472716.KBK24_0105955	1.906e-44	165.0	COG2329@1|root,COG2329@2|Bacteria,1N1IA@1224|Proteobacteria,2VSTH@28216|Betaproteobacteria,1K9B4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM,DUF4188
ZZS3_k127_6841024_7	1192034.CAP_3708	3.344e-127	413.0	COG0583@1|root,COG0583@2|Bacteria,1R6HW@1224|Proteobacteria	1224|Proteobacteria	K	LysR substrate binding domain	-	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6841024_24	1501230.ET33_22955	1.085e-53	196.0	COG0251@1|root,COG0251@2|Bacteria,1V58T@1239|Firmicutes,4HVNR@91061|Bacilli,26WZR@186822|Paenibacillaceae	91061|Bacilli	J	Translation initiation inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS3_k127_6841024_14	1157708.KB907450_gene5765	1.673e-91	304.0	COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2VQ6P@28216|Betaproteobacteria,4AF9X@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
ZZS3_k127_6841024_31	225849.swp_4915	2.327e-14	82.0	2DZ44@1|root,34CCK@2|Bacteria,1P9DN@1224|Proteobacteria,1STGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_8	1268622.AVS7_00526	1.468e-123	414.0	COG3181@1|root,COG3181@2|Bacteria,1N561@1224|Proteobacteria,2VMBJ@28216|Betaproteobacteria,4AD3X@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6841024_32	365046.Rta_10370	3.376e-08	61.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Phenol_MetA_deg
ZZS3_k127_6841024_4	543728.Vapar_2902	1.172e-160	516.0	COG0477@1|root,COG2814@2|Bacteria,1R3YS@1224|Proteobacteria,2VN82@28216|Betaproteobacteria,4ABJN@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
ZZS3_k127_6841024_3	365046.Rta_06040	8.254e-164	522.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,4ACKS@80864|Comamonadaceae	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
ZZS3_k127_6841024_17	883126.HMPREF9710_00911	1.326e-76	261.0	COG2173@1|root,COG2173@2|Bacteria,1RENK@1224|Proteobacteria,2WFWZ@28216|Betaproteobacteria,478U7@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
ZZS3_k127_6841024_10	1123504.JQKD01000039_gene1123	1.943e-115	378.0	COG3618@1|root,COG3618@2|Bacteria,1QWWJ@1224|Proteobacteria,2VMAE@28216|Betaproteobacteria	2|Bacteria	S	amidohydrolase	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Amidohydro_2,Aminotran_3
ZZS3_k127_6841024_5	381666.H16_B2378	2.61e-158	531.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,1K1F3@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_6841024_22	1380394.JADL01000002_gene1437	1.446e-59	211.0	2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria,2JT3N@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_23	358220.C380_17910	4.106e-59	207.0	COG0789@1|root,COG0789@2|Bacteria,1RGW6@1224|Proteobacteria,2VRHE@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
ZZS3_k127_6841024_20	1144319.PMI16_05035	1.295e-71	245.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,2VQ4Q@28216|Betaproteobacteria,474EV@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_6841024_15	292415.Tbd_1070	2.124e-85	289.0	2CHMN@1|root,33RG5@2|Bacteria,1NRC8@1224|Proteobacteria,2W1DZ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_18	1095769.CAHF01000023_gene436	2.016e-75	269.0	2EX35@1|root,33QE6@2|Bacteria,1NQZ5@1224|Proteobacteria,2W001@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_19	365046.Rta_04010	4.218e-75	262.0	COG1280@1|root,COG1280@2|Bacteria,1RF68@1224|Proteobacteria,2VTM6@28216|Betaproteobacteria,4AESM@80864|Comamonadaceae	28216|Betaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
ZZS3_k127_6841024_9	358220.C380_22880	1.114e-121	398.0	COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,2WEVN@28216|Betaproteobacteria,4AJNN@80864|Comamonadaceae	28216|Betaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
ZZS3_k127_6841024_2	296591.Bpro_0080	6.403e-165	524.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2VKS2@28216|Betaproteobacteria,4AH3P@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
ZZS3_k127_6841024_21	1504672.669786839	7.882e-61	231.0	297U7@1|root,2ZV0V@2|Bacteria,1RE3I@1224|Proteobacteria,2VRCN@28216|Betaproteobacteria,4AEKV@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_1	543728.Vapar_0322	9.098e-166	533.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VJAJ@28216|Betaproteobacteria,4ACJ1@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
ZZS3_k127_6841024_30	1458275.AZ34_09530	6.02e-18	90.0	2EN6A@1|root,33FU6@2|Bacteria,1NMD5@1224|Proteobacteria,2VY71@28216|Betaproteobacteria,4AFYU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_29	365046.Rta_29260	2.225e-33	140.0	2E53B@1|root,32ZWF@2|Bacteria,1N7G8@1224|Proteobacteria,2VVPD@28216|Betaproteobacteria,4AEV7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_25	1255043.TVNIR_1769	1.043e-52	208.0	2E502@1|root,32ZTK@2|Bacteria,1NE5Y@1224|Proteobacteria,1SND7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6841024_0	1121939.L861_01165	2.371e-191	609.0	COG0657@1|root,COG0657@2|Bacteria,1MV89@1224|Proteobacteria,1RRR8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
ZZS3_k127_6841024_12	864051.BurJ1DRAFT_0795	1.512e-96	323.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2VQPA@28216|Betaproteobacteria,1KN88@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ZZS3_k127_6841024_6	1223521.BBJX01000002_gene2710	4.242e-135	440.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MUAK@1224|Proteobacteria,2VIS3@28216|Betaproteobacteria,4ACJ3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ZZS3_k127_684423_6	365046.Rta_19620	5.074e-34	130.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,4ACC8@80864|Comamonadaceae	28216|Betaproteobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
ZZS3_k127_684423_1	365044.Pnap_2007	1.774e-137	444.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2VJS5@28216|Betaproteobacteria,4ABFV@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_684423_0	365046.Rta_19640	1.76e-147	488.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2VH0G@28216|Betaproteobacteria,4A9MS@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
ZZS3_k127_684423_2	1223521.BBJX01000004_gene2488	6.941e-86	291.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VP8R@28216|Betaproteobacteria,4AJE4@80864|Comamonadaceae	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
ZZS3_k127_684423_4	338969.Rfer_2548	8.405e-60	212.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VRGJ@28216|Betaproteobacteria,4AJFV@80864|Comamonadaceae	28216|Betaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_684423_5	887062.HGR_03287	1.263e-50	192.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,2VU7D@28216|Betaproteobacteria,4AEXB@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Secreted repeat of	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
ZZS3_k127_684423_3	1157708.KB907450_gene5974	1.03e-78	266.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,4ABND@80864|Comamonadaceae	28216|Betaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
ZZS3_k127_6907035_10	365046.Rta_36820	1.92e-101	331.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,4AC31@80864|Comamonadaceae	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
ZZS3_k127_6907035_4	543728.Vapar_5096	1.794e-164	521.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,4AB7S@80864|Comamonadaceae	28216|Betaproteobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
ZZS3_k127_6907035_7	365046.Rta_36760	2.783e-131	437.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,4AA97@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
ZZS3_k127_6907035_13	232721.Ajs_3934	1.353e-81	274.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,4ADQH@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
ZZS3_k127_6907035_2	365046.Rta_36740	4.908e-192	606.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,4AAU4@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
ZZS3_k127_6907035_6	365046.Rta_36730	6.478e-152	487.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,4A9TY@80864|Comamonadaceae	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
ZZS3_k127_6907035_11	358220.C380_22505	2.105e-95	323.0	COG3240@1|root,COG3240@2|Bacteria,1PEP0@1224|Proteobacteria,2VIHI@28216|Betaproteobacteria,4ABIU@80864|Comamonadaceae	28216|Betaproteobacteria	I	outer membrane autotransporter	-	-	-	ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Lipase_GDSL
ZZS3_k127_6907035_1	365046.Rta_36700	4.127e-193	616.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,4AARG@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS3_k127_6907035_14	358220.C380_22555	3.67e-73	257.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,4AB4B@80864|Comamonadaceae	28216|Betaproteobacteria	O	Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
ZZS3_k127_6907035_15	365046.Rta_36680	4.733e-67	238.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,4AE54@80864|Comamonadaceae	28216|Betaproteobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
ZZS3_k127_6907035_9	365046.Rta_36675	6.412e-105	356.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,4AF1E@80864|Comamonadaceae	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS3_k127_6907035_5	1242864.D187_005431	9.641e-155	493.0	COG1216@1|root,COG1216@2|Bacteria,1R459@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyltransferase (GlcNAc)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc
ZZS3_k127_6907035_8	946483.Cenrod_0213	2.815e-121	437.0	COG2911@1|root,COG2911@2|Bacteria,1QXZF@1224|Proteobacteria	1224|Proteobacteria	M	family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3739,ESPR,Haemagg_act
ZZS3_k127_6907035_0	1276756.AUEX01000012_gene3609	4.287e-277	858.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,4A9RB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_6907035_3	365046.Rta_36650	3.143e-171	539.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VIVF@28216|Betaproteobacteria,4A9WW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_6907035_12	1100721.ALKO01000008_gene2632	2.154e-94	310.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,4A9K6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
ZZS3_k127_6915474_6	365046.Rta_22020	8.55e-64	221.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2VHIZ@28216|Betaproteobacteria,4A9J1@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_6915474_4	365046.Rta_22010	2.362e-81	275.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VS54@28216|Betaproteobacteria,4AE2P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
ZZS3_k127_6915474_10	595537.Varpa_3292	2.636e-06	59.0	2DSYU@1|root,33HZ9@2|Bacteria,1NNHA@1224|Proteobacteria,2VY2P@28216|Betaproteobacteria,4AFYG@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6915474_0	365046.Rta_21990	1.434e-126	413.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,4AAHA@80864|Comamonadaceae	28216|Betaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
ZZS3_k127_6915474_2	543728.Vapar_2637	1.516e-115	379.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,4AAGM@80864|Comamonadaceae	28216|Betaproteobacteria	EJ	PFAM Asparaginase glutaminase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
ZZS3_k127_6915474_7	365046.Rta_21970	1.283e-53	206.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2VVSH@28216|Betaproteobacteria,4AEGG@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6915474_5	365046.Rta_21960	5.371e-65	228.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria,2VRB1@28216|Betaproteobacteria,4AE35@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6915474_3	365046.Rta_21950	2.016e-114	386.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,4AAQG@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
ZZS3_k127_6915474_1	365046.Rta_21940	2.312e-123	400.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,4A9U8@80864|Comamonadaceae	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
ZZS3_k127_6915474_9	1121116.KB894769_gene1345	1.549e-18	88.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,4AFCV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0434 family	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
ZZS3_k127_6915474_8	365046.Rta_21920	1.981e-39	150.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,4AA4B@80864|Comamonadaceae	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
ZZS3_k127_6925399_25	365046.Rta_17790	5.336e-35	134.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,4AF1Z@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
ZZS3_k127_6925399_21	1123504.JQKD01000029_gene4230	4.979e-62	214.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,4ADXV@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
ZZS3_k127_6925399_5	365046.Rta_17810	3.524e-207	647.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,4AAPP@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
ZZS3_k127_6925399_0	365046.Rta_17820	0.0	1364.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,4ABP3@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
ZZS3_k127_6925399_23	614083.AWQR01000018_gene1890	2.778e-57	201.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,4AEBF@80864|Comamonadaceae	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ZZS3_k127_6925399_18	365046.Rta_17840	3.179e-73	249.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,4AEBW@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
ZZS3_k127_6925399_29	59538.XP_005979423.1	3.151e-09	59.0	COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla	33208|Metazoa	C	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
ZZS3_k127_6925399_11	365046.Rta_17850	6.484e-134	432.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,4AATS@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
ZZS3_k127_6925399_22	365046.Rta_17860	6.865e-61	233.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria	2|Bacteria	T	FHA domain	fha	-	-	ko:K07169,ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko02044	3.A.23.1	-	-	FHA
ZZS3_k127_6925399_9	365046.Rta_17870	4.973e-186	604.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_6925399_15	614083.AWQR01000018_gene1885	3.533e-95	315.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,4ABNT@80864|Comamonadaceae	28216|Betaproteobacteria	F	Nudix hydrolase	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
ZZS3_k127_6925399_7	296591.Bpro_2121	8.841e-197	620.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,4ABME@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_6925399_4	365046.Rta_17900	1.19e-245	771.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_6925399_19	365046.Rta_17910	2.007e-68	236.0	COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2VT71@28216|Betaproteobacteria,4AEJZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_6925399_13	365046.Rta_17920	1.628e-113	403.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,4AA1W@80864|Comamonadaceae	28216|Betaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_6925399_8	365046.Rta_17930	1.324e-192	604.0	COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2VM1T@28216|Betaproteobacteria,4AD24@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Cupin 2, conserved barrel domain protein	nagI	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
ZZS3_k127_6925399_2	365046.Rta_17940	6.778e-251	778.0	COG1249@1|root,COG1249@2|Bacteria,1QW6X@1224|Proteobacteria,2WHCB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
ZZS3_k127_6925399_20	365046.Rta_17960	1.001e-64	225.0	COG1846@1|root,COG1846@2|Bacteria,1RJPG@1224|Proteobacteria,2VT4F@28216|Betaproteobacteria,4AEIR@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
ZZS3_k127_6925399_16	365046.Rta_17970	1.853e-90	312.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,4ACMC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	yiaD_1	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
ZZS3_k127_6925399_24	395495.Lcho_3856	1.13e-46	169.0	COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,2VSX8@28216|Betaproteobacteria,1KPCC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
ZZS3_k127_6925399_26	365046.Rta_17980	3.828e-28	132.0	COG0633@1|root,COG0633@2|Bacteria,1PTDB@1224|Proteobacteria,2VTTT@28216|Betaproteobacteria,4AJK6@80864|Comamonadaceae	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
ZZS3_k127_6925399_3	365046.Rta_17990	2.793e-250	805.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2VJHJ@28216|Betaproteobacteria,4A9WI@80864|Comamonadaceae	28216|Betaproteobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
ZZS3_k127_6925399_1	365046.Rta_18000	5.304e-272	841.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VJEA@28216|Betaproteobacteria,4AARF@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS3_k127_6925399_17	365046.Rta_18020	6.045e-76	262.0	COG1296@1|root,COG1296@2|Bacteria,1Q43G@1224|Proteobacteria,2VP0N@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
ZZS3_k127_6925399_10	595537.Varpa_5622	5.68e-151	483.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VJSB@28216|Betaproteobacteria,4AGR7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
ZZS3_k127_6925399_12	365046.Rta_18070	8.584e-118	383.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2VKEU@28216|Betaproteobacteria,4ABBX@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM maleylacetoacetate isomerase	maiA	-	5.2.1.2,5.2.1.4	ko:K01800,ko:K01801	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181,R03868	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
ZZS3_k127_6925399_14	365046.Rta_18080	1.376e-100	344.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,4AA23@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
ZZS3_k127_6925399_28	1286631.X805_01570	2.798e-15	89.0	2E3TT@1|root,32YR7@2|Bacteria,1N9R9@1224|Proteobacteria,2VW0P@28216|Betaproteobacteria,1KMJK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6925399_6	365046.Rta_18090	1.907e-202	640.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,4AB6G@80864|Comamonadaceae	28216|Betaproteobacteria	I	Poly(R)-hydroxyalkanoic acid synthase, class I	phbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
ZZS3_k127_6930166_6	296591.Bpro_3681	8.637e-93	306.0	COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,2VM21@28216|Betaproteobacteria,4AAHG@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rieske 2Fe-2S domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS3_k127_6930166_1	398578.Daci_0965	7.028e-160	509.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2VH98@28216|Betaproteobacteria,4ADC3@80864|Comamonadaceae	28216|Betaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.1.1.404	ko:K21607	ko00361,ko01100,ko01120,map00361,map01100,map01120	-	R11585	-	ko00000,ko00001,ko01000	-	-	-	Fer2,NAD_binding_1
ZZS3_k127_6930166_2	296591.Bpro_3679	1.065e-148	478.0	COG3203@1|root,COG3203@2|Bacteria,1R5T2@1224|Proteobacteria,2VMH6@28216|Betaproteobacteria,4ACZH@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM porin Gram-negative type	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
ZZS3_k127_6930166_5	864073.HFRIS_021296	1.209e-115	377.0	2AJB8@1|root,319WE@2|Bacteria,1Q492@1224|Proteobacteria,2WCW8@28216|Betaproteobacteria,478AV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
ZZS3_k127_6930166_7	1123504.JQKD01000007_gene3485	4.204e-76	263.0	COG3427@1|root,COG3427@2|Bacteria,1R77T@1224|Proteobacteria,2VIC2@28216|Betaproteobacteria,4AGK0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
ZZS3_k127_6930166_8	485913.Krac_6954	9.081e-51	197.0	COG2080@1|root,COG2080@2|Bacteria,2G8FG@200795|Chloroflexi	200795|Chloroflexi	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_2
ZZS3_k127_6930166_4	1123504.JQKD01000007_gene3483	1.188e-125	413.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria,4AJ77@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
ZZS3_k127_6930166_0	1123504.JQKD01000007_gene3482	0.0	1102.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,4ACW2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ZZS3_k127_6930166_3	1123504.JQKD01000007_gene3481	1.228e-145	469.0	COG3181@1|root,COG3181@2|Bacteria,1R61G@1224|Proteobacteria,2VIUX@28216|Betaproteobacteria,4AH34@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_6930166_9	1366050.N234_24555	3.573e-26	124.0	COG1846@1|root,COG1846@2|Bacteria,1RJUF@1224|Proteobacteria,2VTKZ@28216|Betaproteobacteria,1KC4P@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_6948876_2	365046.Rta_10450	7.865e-172	551.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,4A9YA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_6948876_4	365046.Rta_10460	4.377e-93	310.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,4ABKA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ebsC	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
ZZS3_k127_6948876_5	365046.Rta_10470	3.138e-91	313.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,4ABGB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
ZZS3_k127_6948876_0	365046.Rta_10550	4.676e-247	772.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2VH3E@28216|Betaproteobacteria,4ABVN@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
ZZS3_k127_6948876_7	296591.Bpro_1595	1.549e-73	258.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,4ADJG@80864|Comamonadaceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
ZZS3_k127_6948876_6	365046.Rta_10570	1.002e-81	281.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,4ADFY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
ZZS3_k127_6948876_1	365046.Rta_10580	4.028e-178	586.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,4AA6J@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
ZZS3_k127_6948876_8	296591.Bpro_2330	3.222e-45	168.0	2DMYT@1|root,32UF9@2|Bacteria,1N01P@1224|Proteobacteria,2VUE2@28216|Betaproteobacteria,4AF48@80864|Comamonadaceae	28216|Betaproteobacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
ZZS3_k127_6948876_9	543728.Vapar_3604	5.005e-27	123.0	2DMYT@1|root,32UF9@2|Bacteria,1N01P@1224|Proteobacteria,2VUE2@28216|Betaproteobacteria,4AF48@80864|Comamonadaceae	28216|Betaproteobacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
ZZS3_k127_6948876_3	270374.MELB17_10988	1.271e-106	348.0	COG0500@1|root,COG2226@2|Bacteria,1QU8Z@1224|Proteobacteria,1RS1E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
ZZS3_k127_7001284_9	1458357.BG58_06445	2.035e-12	70.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,1K23R@119060|Burkholderiaceae	28216|Betaproteobacteria	H	2-dehydropantoate 2-reductase	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
ZZS3_k127_7001284_4	365046.Rta_01710	1.57e-131	424.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VM54@28216|Betaproteobacteria,4AAA9@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
ZZS3_k127_7001284_5	365046.Rta_01760	3.361e-104	355.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VK64@28216|Betaproteobacteria,4ACQ6@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS3_k127_7001284_3	365046.Rta_01770	5.998e-132	445.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2VH5E@28216|Betaproteobacteria,4ABW1@80864|Comamonadaceae	28216|Betaproteobacteria	Q	TIGRFAM 2-oxo-hepta-3-ene-1,7-dioic acid hydratase	-	-	-	ko:K02509	ko00350,ko01120,map00350,map01120	-	R04132,R06897	RC01615,RC02595	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_7001284_6	1157708.KB907466_gene647	1.151e-66	228.0	COG3232@1|root,COG3232@2|Bacteria,1RB8A@1224|Proteobacteria,2VRSE@28216|Betaproteobacteria,4AE9A@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM 5-carboxymethyl-2-hydroxymuconate isomerase	hpaF	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	CHMI
ZZS3_k127_7001284_1	1157708.KB907466_gene648	1.011e-162	520.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VTUV@28216|Betaproteobacteria,4AET5@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	1.13.11.16,1.13.11.8	ko:K04101,ko:K05713	ko00360,ko00362,ko00624,ko00627,ko01120,ko01220,map00360,map00362,map00624,map00627,map01120,map01220	M00545	R01632,R03550,R04280,R04376,R06788,R09565	RC00233,RC00387,RC00535,RC01140,RC01364,RC02567,RC02694	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
ZZS3_k127_7001284_7	595537.Varpa_0245	6.505e-54	194.0	2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2W38B@28216|Betaproteobacteria,4AI49@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
ZZS3_k127_7001284_0	398578.Daci_0106	5.677e-296	910.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,4AB55@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	hpaE	-	1.2.1.60	ko:K00151	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04418	RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_7001284_2	365046.Rta_01810	5.156e-139	447.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VMPC@28216|Betaproteobacteria,4AC5I@80864|Comamonadaceae	28216|Betaproteobacteria	Q	TIGRFAM 4-hydroxyphenylacetate degradation bifunctional isomerase decarboxylase,HpaG2 subunit	-	-	4.1.1.68	ko:K05921	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04134,R04380	RC01085,RC02669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
ZZS3_k127_7001284_8	392499.Swit_0361	2.205e-24	104.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2U6TR@28211|Alphaproteobacteria,2KCSV@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
ZZS3_k127_7005121_6	1158292.JPOE01000005_gene135	4.066e-14	71.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1KJGX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS3_k127_7005121_7	1177179.A11A3_14602	2.508e-13	75.0	2EGR5@1|root,33AHA@2|Bacteria,1NH3C@1224|Proteobacteria,1SIE7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7005121_5	365046.Rta_27900	9.981e-46	176.0	COG0727@1|root,COG0727@2|Bacteria,1N027@1224|Proteobacteria,2VU3Y@28216|Betaproteobacteria,4AEXK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
ZZS3_k127_7005121_4	296591.Bpro_3588	9.282e-117	381.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2VHG4@28216|Betaproteobacteria,4ABNH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
ZZS3_k127_7005121_0	365044.Pnap_3019	1.027e-219	692.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2VIP0@28216|Betaproteobacteria,4AAXE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
ZZS3_k127_7005121_1	1265502.KB905934_gene3237	2.037e-155	493.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,2VJG3@28216|Betaproteobacteria,4ACUT@80864|Comamonadaceae	28216|Betaproteobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
ZZS3_k127_7005121_3	1458275.AZ34_12370	1.037e-134	441.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2VISJ@28216|Betaproteobacteria,4ABG7@80864|Comamonadaceae	28216|Betaproteobacteria	CH	PFAM monooxygenase FAD-binding	-	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_7005121_2	688245.CtCNB1_3356	1.031e-135	436.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,4A9W6@80864|Comamonadaceae	28216|Betaproteobacteria	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS3_k127_7015022_11	335659.S23_69390	2.358e-11	67.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JTZB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	MA20_23605	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7015022_7	935840.JAEQ01000019_gene2100	8.334e-67	239.0	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,2TU0X@28211|Alphaproteobacteria,43M7T@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7015022_9	864051.BurJ1DRAFT_4259	5.289e-29	130.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2VVUD@28216|Betaproteobacteria,1KMNK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	TfoX N-terminal domain	tfoX	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
ZZS3_k127_7015022_3	596154.Alide2_0496	2.05e-153	490.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,4AC3Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7015022_2	358220.C380_00560	1.978e-164	563.0	COG1506@1|root,COG1506@2|Bacteria,1R51S@1224|Proteobacteria,2VID9@28216|Betaproteobacteria,4AASA@80864|Comamonadaceae	28216|Betaproteobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7015022_0	1123504.JQKD01000012_gene1386	0.0	1169.0	COG0412@1|root,COG0412@2|Bacteria,1QV1D@1224|Proteobacteria,2VJQK@28216|Betaproteobacteria,4AD8M@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
ZZS3_k127_7015022_6	595537.Varpa_2147	1.094e-81	282.0	COG3181@1|root,COG3181@2|Bacteria,1N561@1224|Proteobacteria,2VMBJ@28216|Betaproteobacteria,4AD3X@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7015022_5	398578.Daci_1893	1.8e-116	398.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2VQ8X@28216|Betaproteobacteria,4ACXQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7015022_8	1123504.JQKD01000035_gene2691	9.852e-56	204.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,4ADHQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein, hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
ZZS3_k127_7015022_1	398578.Daci_1163	1.562e-179	588.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VKZU@28216|Betaproteobacteria,4ABYC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
ZZS3_k127_7015022_4	1123504.JQKD01000011_gene2422	2.704e-149	479.0	COG3181@1|root,COG3181@2|Bacteria,1NU8P@1224|Proteobacteria,2W1HG@28216|Betaproteobacteria,4AGHC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7015022_10	1123504.JQKD01000011_gene2421	6.451e-20	89.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VM0U@28216|Betaproteobacteria,4AB0P@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_7020961_10	365046.Rta_34520	2.626e-98	324.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,4ADJC@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM N-acetylmuramoyl-L-alanine amidase family 2	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
ZZS3_k127_7020961_4	365044.Pnap_3383	6.477e-197	625.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9WN@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_7020961_6	365046.Rta_34500	5.226e-172	557.0	COG0642@1|root,COG0642@2|Bacteria,1QXJ6@1224|Proteobacteria,2WH5B@28216|Betaproteobacteria,4ACHH@80864|Comamonadaceae	28216|Betaproteobacteria	T	Signal transduction histidine kinase	pehS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
ZZS3_k127_7020961_11	365046.Rta_34490	8.518e-18	95.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,4AFXR@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_7020961_9	365046.Rta_34480	8.518e-123	398.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,4A9WR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cytochrome C assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
ZZS3_k127_7020961_1	365046.Rta_34470	2.407e-260	807.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,4ABMX@80864|Comamonadaceae	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
ZZS3_k127_7020961_5	1286631.X805_24800	1.983e-172	550.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2VHU2@28216|Betaproteobacteria,1KJT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS3_k127_7020961_3	365046.Rta_34460	3.254e-225	702.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,4ABPK@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_7020961_8	365046.Rta_34450	1.112e-140	472.0	COG3181@1|root,COG3181@2|Bacteria,1QG04@1224|Proteobacteria,2VPJQ@28216|Betaproteobacteria,4AAQI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7020961_0	365046.Rta_34440	2.328e-308	982.0	COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,2VHDC@28216|Betaproteobacteria,4A9RK@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 2	opgH	-	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3,Glycos_transf_2
ZZS3_k127_7020961_2	358220.C380_19795	6.073e-229	719.0	COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,2VJBC@28216|Betaproteobacteria,4ABBR@80864|Comamonadaceae	28216|Betaproteobacteria	P	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)	mdoG	-	-	ko:K03670	-	-	-	-	ko00000	-	-	-	MdoG
ZZS3_k127_7020961_7	365046.Rta_34420	3.43e-161	511.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9V8@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator	yfhA	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_7053157_0	1276756.AUEX01000011_gene1249	5.378e-268	831.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,4AA9X@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
ZZS3_k127_7053157_3	1123504.JQKD01000024_gene280	1.619e-132	425.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,4AANU@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
ZZS3_k127_7053157_1	365044.Pnap_1729	9.461e-226	715.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,4A9X8@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
ZZS3_k127_7053157_2	365046.Rta_21180	8.818e-146	490.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,4A9TR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
ZZS3_k127_7053157_6	365046.Rta_21170	1.938e-58	222.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,4AE0B@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS3_k127_7053157_5	365046.Rta_21160	1.659e-78	268.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,4ADH1@80864|Comamonadaceae	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
ZZS3_k127_7053157_4	365046.Rta_21145	3.324e-99	327.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,4ADGX@80864|Comamonadaceae	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
ZZS3_k127_7057829_3	1502852.FG94_00722	6.09e-210	662.0	COG1132@1|root,COG1132@2|Bacteria,1QFQD@1224|Proteobacteria,2VKMM@28216|Betaproteobacteria,47667@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS3_k127_7057829_13	296591.Bpro_2843	7.515e-147	479.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2VJQC@28216|Betaproteobacteria,4AFG7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ZZS3_k127_7057829_6	296591.Bpro_2842	3.763e-171	542.0	COG3391@1|root,COG3391@2|Bacteria,1R7H9@1224|Proteobacteria,2VP5F@28216|Betaproteobacteria,4AGZ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7057829_12	296591.Bpro_2838	1.192e-149	504.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VKTJ@28216|Betaproteobacteria,4AGP1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
ZZS3_k127_7057829_4	1286631.X805_16950	4.008e-194	623.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,1KKIQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K11690,ko:K21393	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
ZZS3_k127_7057829_20	1286631.X805_16940	3.195e-63	226.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689,ko:K21394	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
ZZS3_k127_7057829_8	1286631.X805_16930	1.15e-159	509.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,1KN34@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
ZZS3_k127_7057829_16	1286631.X805_16920	2.399e-125	409.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2VPDK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Amidohydrolase 2	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
ZZS3_k127_7057829_9	595537.Varpa_1121	5.644e-156	498.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VIEI@28216|Betaproteobacteria,4AARS@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.2.1.43,4.3.3.7	ko:K01714,ko:K13876	ko00053,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02278,R10147	RC00429,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS3_k127_7057829_1	381666.H16_A2758	2.785e-265	823.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,1K0EB@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	-	-	4.2.1.42,4.2.1.7,4.4.1.24	ko:K01685,ko:K01708,ko:K16846	ko00040,ko00053,ko00270,ko01100,map00040,map00053,map00270,map01100	M00631	R01540,R05608,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ZZS3_k127_7057829_2	391735.Veis_2709	1.95e-240	764.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2VK18@28216|Betaproteobacteria,4AD5T@80864|Comamonadaceae	28216|Betaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_7057829_11	1286631.X805_16670	3.849e-150	498.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,1KJ36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	-	-	-	-	-	-	-	-	-	-	-	-	PdxA
ZZS3_k127_7057829_15	296591.Bpro_2834	7.126e-137	442.0	COG3181@1|root,COG3181@2|Bacteria,1QW9H@1224|Proteobacteria,2VJ0I@28216|Betaproteobacteria,4ACFG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7057829_17	399795.CtesDRAFT_PD0677	3.185e-121	396.0	COG0583@1|root,COG0583@2|Bacteria,1R6FT@1224|Proteobacteria,2VPQE@28216|Betaproteobacteria,4A9ZG@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7057829_29	1380387.JADM01000002_gene1949	1.828e-06	51.0	COG2207@1|root,COG2207@2|Bacteria,1RD0U@1224|Proteobacteria,1SNMM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS3_k127_7057829_21	1268622.AVS7_00778	5.776e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2VJ7V@28216|Betaproteobacteria,4AIZ1@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_7057829_14	398578.Daci_0378	5.941e-143	480.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VJRQ@28216|Betaproteobacteria,4AC9C@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c
ZZS3_k127_7057829_30	1123504.JQKD01000033_gene5230	0.0001325	54.0	28KVQ@1|root,2ZAC8@2|Bacteria,1R8AN@1224|Proteobacteria,2VKY6@28216|Betaproteobacteria,4AGE1@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7057829_18	296591.Bpro_2393	7.505e-93	308.0	COG1280@1|root,COG1280@2|Bacteria,1R5K2@1224|Proteobacteria,2VPC2@28216|Betaproteobacteria,4A9ZZ@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
ZZS3_k127_7057829_7	365046.Rta_31670	2.923e-169	535.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,4A9J5@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ZZS3_k127_7057829_23	1316927.ATKI01000016_gene1679	3.282e-53	192.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,1TAJ8@1236|Gammaproteobacteria,1YS8E@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
ZZS3_k127_7057829_28	864051.BurJ1DRAFT_2613	3.088e-12	69.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,1KP8B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7057829_26	314256.OG2516_06896	9.165e-23	103.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,2PDY8@252301|Oceanicola	28211|Alphaproteobacteria	O	peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
ZZS3_k127_7057829_24	762376.AXYL_05489	3.642e-50	186.0	COG1764@1|root,COG1764@2|Bacteria,1RIB3@1224|Proteobacteria,2VTMC@28216|Betaproteobacteria	28216|Betaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS3_k127_7057829_22	1114970.PSF113_1866	1.412e-59	212.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,1TAJ8@1236|Gammaproteobacteria,1YS8E@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
ZZS3_k127_7057829_25	448385.sce1529	1.846e-37	164.0	COG1917@1|root,COG1917@2|Bacteria,1PJUF@1224|Proteobacteria,43580@68525|delta/epsilon subdivisions,2X96P@28221|Deltaproteobacteria,2Z28V@29|Myxococcales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_7057829_0	1366050.N234_10625	0.0	1597.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2W1MJ@28216|Betaproteobacteria,1KC8V@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
ZZS3_k127_7057829_19	710686.Mycsm_01682	8.501e-90	302.0	28MQW@1|root,2ZAZK@2|Bacteria,2GM6G@201174|Actinobacteria,235C2@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7057829_10	748247.AZKH_2577	1.551e-154	516.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,2KV30@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane efflux protein	-	-	-	ko:K18903	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17.3.3	-	-	OEP
ZZS3_k127_7057829_5	420662.Mpe_A0868	4.048e-175	553.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ2M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	AcrB/AcrD/AcrF family	bepE_1	-	-	ko:K03296,ko:K18138,ko:K18902	ko01501,ko01503,map01501,map01503	M00647,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_7069663_15	365046.Rta_13370	4.045e-81	276.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ75@28216|Betaproteobacteria,4ADHR@80864|Comamonadaceae	28216|Betaproteobacteria	C	2Fe-2S -binding domain protein	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
ZZS3_k127_7069663_6	365046.Rta_13360	3.106e-156	502.0	COG3284@1|root,COG3284@2|Bacteria,1MVRZ@1224|Proteobacteria,2VJBH@28216|Betaproteobacteria,4AAJA@80864|Comamonadaceae	28216|Betaproteobacteria	KQ	helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8
ZZS3_k127_7069663_16	365046.Rta_13320	9.772e-79	288.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,4AC9G@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
ZZS3_k127_7069663_10	365046.Rta_13310	1.998e-106	363.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,4AD27@80864|Comamonadaceae	28216|Betaproteobacteria	P	Molybdate ABC transporter inner membrane subunit	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
ZZS3_k127_7069663_8	1458275.AZ34_13210	2.736e-136	445.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,4AAQE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
ZZS3_k127_7069663_14	1041159.AZUW01000016_gene1494	3.494e-84	286.0	COG0428@1|root,COG0428@2|Bacteria,1QDFV@1224|Proteobacteria,2U492@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
ZZS3_k127_7069663_17	1278073.MYSTI_03704	3.433e-68	238.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2X0CC@28221|Deltaproteobacteria,2Z0IE@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
ZZS3_k127_7069663_4	864051.BurJ1DRAFT_3478	1.963e-162	533.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1QWXX@1224|Proteobacteria,2WHFU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
ZZS3_k127_7069663_3	1157708.KB907450_gene5778	2.549e-183	590.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VNYR@28216|Betaproteobacteria,4AJ6B@80864|Comamonadaceae	28216|Betaproteobacteria	P	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_7069663_9	365046.Rta_13250	5.933e-123	413.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2VJQG@28216|Betaproteobacteria,4ABKV@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM extracellular solute-binding protein family 1	tupB	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
ZZS3_k127_7069663_13	365046.Rta_13240	4.017e-93	323.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2VJYN@28216|Betaproteobacteria,4AD50@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
ZZS3_k127_7069663_12	543728.Vapar_1588	1.373e-97	325.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2VNEC@28216|Betaproteobacteria,4AAPB@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	tupB	-	3.6.3.55	ko:K05773,ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
ZZS3_k127_7069663_7	365046.Rta_13220	3.956e-151	492.0	COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,2VH5J@28216|Betaproteobacteria,4A9MK@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM regulatory protein, LysR	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_1,PBP_like
ZZS3_k127_7069663_5	365046.Rta_13200	4.139e-162	520.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4ABSP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
ZZS3_k127_7069663_11	365046.Rta_13190	3.584e-104	342.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VRCB@28216|Betaproteobacteria,4AAJY@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_7069663_1	365046.Rta_13180	7.011e-287	890.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,4ABNC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	DctM
ZZS3_k127_7069663_20	1265502.KB905936_gene2686	1.633e-36	142.0	COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,2VVWW@28216|Betaproteobacteria,4AFTX@80864|Comamonadaceae	28216|Betaproteobacteria	P	Na+/H+ antiporter subunit	mnhG	-	-	ko:K05564	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	PhaG_MnhG_YufB
ZZS3_k127_7069663_22	1000565.METUNv1_01240	1.54e-23	111.0	COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria,2VWC1@28216|Betaproteobacteria,2KZGY@206389|Rhodocyclales	206389|Rhodocyclales	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05563	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MrpF_PhaF
ZZS3_k127_7069663_18	1265502.KB905936_gene2688	8.011e-48	178.0	COG1863@1|root,COG1863@2|Bacteria,1RH9F@1224|Proteobacteria,2VSM8@28216|Betaproteobacteria,4AE5S@80864|Comamonadaceae	28216|Betaproteobacteria	P	antiporter	phaE	-	-	ko:K05562	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MNHE
ZZS3_k127_7069663_2	1265502.KB905936_gene2689	2.228e-193	625.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2VH1Y@28216|Betaproteobacteria,4AAUG@80864|Comamonadaceae	28216|Betaproteobacteria	CP	NADH Ubiquinone plastoquinone (Complex I)	mnhD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
ZZS3_k127_7069663_19	1000565.METUNv1_01243	3.221e-43	183.0	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,2VSVU@28216|Betaproteobacteria,2KZ68@206389|Rhodocyclales	206389|Rhodocyclales	P	NADH-ubiquinone oxidoreductase chain 4L	-	-	-	ko:K05560	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Oxidored_q2
ZZS3_k127_7069663_0	1000565.METUNv1_01244	0.0	1150.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2VK56@28216|Betaproteobacteria,2KXWA@206389|Rhodocyclales	206389|Rhodocyclales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	-	ko:K05559	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
ZZS3_k127_7078159_4	365046.Rta_07010	1.262e-77	262.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,4ADH4@80864|Comamonadaceae	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
ZZS3_k127_7078159_5	1268622.AVS7_00108	5.899e-69	242.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,4ADIJ@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
ZZS3_k127_7078159_3	365046.Rta_07030	3.171e-106	350.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,4ABAS@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7078159_7	365046.Rta_07040	4.606e-55	195.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,4AEHA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ZZS3_k127_7078159_6	1276756.AUEX01000040_gene336	1.697e-68	234.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,4ADZS@80864|Comamonadaceae	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
ZZS3_k127_7078159_2	365046.Rta_07060	5.29e-157	509.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,4AAHZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
ZZS3_k127_7078159_1	365046.Rta_07070	3.133e-170	546.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,4AB4U@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS3_k127_7078159_0	1100720.ALKN01000031_gene1203	8.953e-227	709.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,4AA2G@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
ZZS3_k127_7078159_8	296591.Bpro_4103	9.386e-22	94.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VM00@28216|Betaproteobacteria,4ABHF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
ZZS3_k127_7094587_6	269796.Rru_A1990	8.535e-13	73.0	COG1572@1|root,COG1572@2|Bacteria,1NBW4@1224|Proteobacteria,2UFMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7094587_5	1121033.AUCF01000006_gene4144	8.222e-81	278.0	COG4711@1|root,COG4711@2|Bacteria,1R9Y5@1224|Proteobacteria,2U58R@28211|Alphaproteobacteria,2JW36@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative integral membrane protein (DUF2391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2391
ZZS3_k127_7094587_1	296591.Bpro_4738	7.282e-234	728.0	COG4664@1|root,COG4664@2|Bacteria,1QU8F@1224|Proteobacteria,2VKVK@28216|Betaproteobacteria,4AGQC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_7094587_4	296591.Bpro_4737	5.25e-87	292.0	COG3090@1|root,COG3090@2|Bacteria,1RA8Q@1224|Proteobacteria,2VWND@28216|Betaproteobacteria,4AGGN@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ZZS3_k127_7094587_3	365046.Rta_32510	2.943e-180	568.0	COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2VM5I@28216|Betaproteobacteria,4AGQZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_7094587_2	296591.Bpro_4735	2.582e-186	627.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2VMSN@28216|Betaproteobacteria,4ABYN@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
ZZS3_k127_7094587_0	296591.Bpro_4734	0.0	1208.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
ZZS3_k127_7094587_7	1122931.AUAE01000038_gene2831	7.685e-11	65.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,2FMJS@200643|Bacteroidia,22X9C@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_7108088_8	1380358.JADJ01000021_gene3763	6.601e-16	84.0	COG0654@1|root,COG0654@2|Bacteria,1MX9R@1224|Proteobacteria,1SYDP@1236|Gammaproteobacteria,1XNTQ@135619|Oceanospirillales	135619|Oceanospirillales	CH	FAD binding domain	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_7108088_6	365044.Pnap_0614	8.361e-75	260.0	COG0346@1|root,COG0346@2|Bacteria,1MUBT@1224|Proteobacteria,2VSNX@28216|Betaproteobacteria,4AFYM@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_7108088_0	365046.Rta_18290	7.876e-189	594.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2VJ6S@28216|Betaproteobacteria,4AA2B@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7,4.4.1.15,4.4.1.25	ko:K01505,ko:K05396,ko:K17950	ko00270,map00270	-	R00997,R01874,R07634	RC00382,RC00419,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
ZZS3_k127_7108088_5	296591.Bpro_4755	2.35e-104	345.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2VHS8@28216|Betaproteobacteria,4ACWG@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
ZZS3_k127_7108088_4	365046.Rta_29370	1.167e-131	422.0	COG0684@1|root,COG0684@2|Bacteria,1R574@1224|Proteobacteria,2VTA3@28216|Betaproteobacteria,4AETR@80864|Comamonadaceae	28216|Betaproteobacteria	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ZZS3_k127_7108088_1	365046.Rta_29360	3.395e-168	546.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7108088_3	1218084.BBJK01000178_gene7956	2.261e-133	433.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VHH9@28216|Betaproteobacteria,1K07T@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_7108088_2	365046.Rta_29350	4.121e-156	496.0	COG0583@1|root,COG0583@2|Bacteria,1QU1H@1224|Proteobacteria,2VIC7@28216|Betaproteobacteria,4AE7Q@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7108088_7	365046.Rta_29340	1.509e-44	164.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VP9T@28216|Betaproteobacteria,4ACDH@80864|Comamonadaceae	28216|Betaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_7118726_12	365046.Rta_23220	2.165e-35	136.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,4ACT7@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_7118726_9	358220.C380_09395	1.133e-78	269.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,4ADK4@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
ZZS3_k127_7118726_4	365046.Rta_23200	1.032e-171	551.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,4AB53@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA_2	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	HlyD_D23
ZZS3_k127_7118726_0	365046.Rta_23190	0.0	1697.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4A9T5@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_2	-	-	ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
ZZS3_k127_7118726_13	296591.Bpro_2284	2.822e-32	128.0	COG1977@1|root,COG1977@2|Bacteria,1PWGT@1224|Proteobacteria,2WC1B@28216|Betaproteobacteria,4AIQ1@80864|Comamonadaceae	28216|Betaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
ZZS3_k127_7118726_3	296591.Bpro_2285	1.162e-180	576.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7118726_2	296591.Bpro_2286	7.394e-187	597.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,4AAFY@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
ZZS3_k127_7118726_7	365046.Rta_23130	2.706e-96	324.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,4ABJP@80864|Comamonadaceae	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ZZS3_k127_7118726_1	1223521.BBJX01000005_gene1991	3.751e-191	602.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,4AB8M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
ZZS3_k127_7118726_5	365046.Rta_23110	2.038e-143	458.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4ACE3@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	tsaC	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_7118726_10	987059.RBXJA2T_05218	1.496e-56	205.0	2EDW0@1|root,32VXH@2|Bacteria,1Q0AC@1224|Proteobacteria,2W51V@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7118726_8	987059.RBXJA2T_05213	1.922e-95	336.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VJK2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19,TPR_8
ZZS3_k127_7118726_14	987059.RBXJA2T_05208	1.34e-28	124.0	2EAQM@1|root,334SV@2|Bacteria,1N39W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7118726_11	1121920.AUAU01000005_gene1079	7.169e-53	194.0	2EDW0@1|root,32VXH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7118726_6	987059.RBXJA2T_05213	1.439e-107	372.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VJK2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19,TPR_8
ZZS3_k127_7118726_15	1549858.MC45_03585	3.763e-12	77.0	2EAQM@1|root,334SV@2|Bacteria,1N39W@1224|Proteobacteria,2UE2Z@28211|Alphaproteobacteria,2K4QC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7129641_5	365046.Rta_22300	4.223e-34	131.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,4ACAF@80864|Comamonadaceae	28216|Betaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
ZZS3_k127_7129641_0	365046.Rta_22310	0.0	1024.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,2VKSK@28216|Betaproteobacteria,4AC2A@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
ZZS3_k127_7129641_2	365046.Rta_22320	3.354e-148	475.0	COG0703@1|root,COG1396@1|root,COG0703@2|Bacteria,COG1396@2|Bacteria,1MX66@1224|Proteobacteria,2VK91@28216|Betaproteobacteria,4ABJG@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	ko:K15546	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,SKI
ZZS3_k127_7129641_3	365046.Rta_22330	3.141e-84	282.0	COG0369@1|root,COG0369@2|Bacteria,1QUX0@1224|Proteobacteria,2VVK4@28216|Betaproteobacteria,4AFAS@80864|Comamonadaceae	28216|Betaproteobacteria	P	Flavodoxin	-	-	-	ko:K06205	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
ZZS3_k127_7129641_1	365046.Rta_22340	5.767e-289	893.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,4AC26@80864|Comamonadaceae	28216|Betaproteobacteria	I	Benzoate-CoA ligase family	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
ZZS3_k127_7129641_4	365046.Rta_22350	7.165e-57	200.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VIK5@28216|Betaproteobacteria,4ABK8@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_7141856_20	614083.AWQR01000010_gene1630	8.714e-23	97.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,2VHC5@28216|Betaproteobacteria,4A9P8@80864|Comamonadaceae	28216|Betaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
ZZS3_k127_7141856_9	365046.Rta_12020	1.143e-95	324.0	COG1028@1|root,COG1028@2|Bacteria,1RH9P@1224|Proteobacteria,2VNFB@28216|Betaproteobacteria,4ABK2@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_7141856_11	1123504.JQKD01000041_gene2842	1.457e-90	302.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2VQFX@28216|Betaproteobacteria,4ADV4@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
ZZS3_k127_7141856_13	292415.Tbd_0658	1.187e-83	287.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Pseudouridine synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
ZZS3_k127_7141856_16	1458275.AZ34_12575	5.272e-64	220.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,4AE2H@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
ZZS3_k127_7141856_6	1276756.AUEX01000009_gene1786	1.036e-112	368.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,4AB1P@80864|Comamonadaceae	28216|Betaproteobacteria	P	phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
ZZS3_k127_7141856_2	614083.AWQR01000010_gene1550	2.176e-188	591.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,4AA1C@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
ZZS3_k127_7141856_14	365046.Rta_12080	9.441e-72	255.0	COG2314@1|root,COG2314@2|Bacteria,1RD84@1224|Proteobacteria,2VSV6@28216|Betaproteobacteria,4AE86@80864|Comamonadaceae	28216|Betaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
ZZS3_k127_7141856_12	365046.Rta_12090	1.598e-87	291.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,4ADKG@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM GCN5-related N-acetyltransferase	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
ZZS3_k127_7141856_18	365046.Rta_12100	1.057e-41	154.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,4AF0Y@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
ZZS3_k127_7141856_10	358220.C380_06770	8.47e-91	303.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,4ADPE@80864|Comamonadaceae	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
ZZS3_k127_7141856_5	543728.Vapar_1475	1.396e-118	387.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,4ABE9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
ZZS3_k127_7141856_17	1123504.JQKD01000010_gene2543	9.923e-64	223.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,4ADW5@80864|Comamonadaceae	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
ZZS3_k127_7141856_7	365046.Rta_12140	2.556e-108	358.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,4AB1G@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS3_k127_7141856_3	365046.Rta_12150	1.117e-155	499.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,4AAHV@80864|Comamonadaceae	28216|Betaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
ZZS3_k127_7141856_15	338969.Rfer_1123	4.59e-65	225.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,4ADZP@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Thioredoxin domain	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
ZZS3_k127_7141856_4	358220.C380_06795	1.116e-139	449.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,4AC0J@80864|Comamonadaceae	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
ZZS3_k127_7141856_19	365046.Rta_12170	1.282e-39	169.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,4AEJH@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
ZZS3_k127_7141856_0	365046.Rta_12180	1.112e-231	721.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,4AA3U@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM peptidase M48 Ste24p	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
ZZS3_k127_7141856_8	596153.Alide_1214	1.362e-96	318.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,4A9QS@80864|Comamonadaceae	28216|Betaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
ZZS3_k127_7141856_1	365046.Rta_12200	2.073e-221	697.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,4AA2F@80864|Comamonadaceae	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
ZZS3_k127_7152635_4	1157708.KB907452_gene3608	6.006e-108	355.0	COG1073@1|root,COG1073@2|Bacteria,1NXZW@1224|Proteobacteria,2VNFH@28216|Betaproteobacteria,4AGAU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4,Peptidase_S9
ZZS3_k127_7152635_3	426117.M446_6154	1.592e-115	383.0	28HHS@1|root,2Z7TD@2|Bacteria,1R7VF@1224|Proteobacteria,2U1A8@28211|Alphaproteobacteria,1JR3C@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3182
ZZS3_k127_7152635_1	543728.Vapar_1702	4.213e-165	526.0	COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2VZ9P@28216|Betaproteobacteria,4AHXB@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS3_k127_7152635_5	375286.mma_0053	4.237e-69	248.0	COG2120@1|root,COG2120@2|Bacteria,1PUV7@1224|Proteobacteria,2WAY3@28216|Betaproteobacteria,474B5@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS3_k127_7152635_0	365046.Rta_10510	7.243e-218	685.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VK5F@28216|Betaproteobacteria,4AC03@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdV	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_7152635_2	365046.Rta_10500	1.411e-151	484.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VKC1@28216|Betaproteobacteria,4ABYH@80864|Comamonadaceae	28216|Betaproteobacteria	C	e3 binding domain	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_7191490_5	365046.Rta_03610	2.303e-127	407.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,4AAUZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS3_k127_7191490_14	365046.Rta_03620	1.565e-69	248.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,4ADIK@80864|Comamonadaceae	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
ZZS3_k127_7191490_8	391735.Veis_2946	2.317e-92	310.0	COG0664@1|root,COG0664@2|Bacteria,1PVIF@1224|Proteobacteria,2VXNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_7191490_1	391735.Veis_2945	5.514e-189	603.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria	1224|Proteobacteria	E	aminotransferase class V	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
ZZS3_k127_7191490_18	391735.Veis_2944	3.244e-32	142.0	COG3266@1|root,COG3266@2|Bacteria,1Q06Q@1224|Proteobacteria,2W5SK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7191490_3	391735.Veis_2943	1.637e-143	469.0	COG3181@1|root,COG3181@2|Bacteria,1N00G@1224|Proteobacteria,2VN46@28216|Betaproteobacteria,4ABNY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7191490_17	391735.Veis_2942	2.125e-49	194.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2VY6Q@28216|Betaproteobacteria,4AFUM@80864|Comamonadaceae	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS3_k127_7191490_4	159450.NH14_00035	5.3e-136	445.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,2VIPT@28216|Betaproteobacteria,1K6DT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
ZZS3_k127_7191490_15	365046.Rta_03620	6.006e-67	230.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,4ADIK@80864|Comamonadaceae	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
ZZS3_k127_7191490_16	1500894.JQNN01000001_gene2683	3.139e-57	213.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,47478@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
ZZS3_k127_7191490_13	365046.Rta_03730	2.884e-71	254.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria,4AE80@80864|Comamonadaceae	28216|Betaproteobacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
ZZS3_k127_7191490_6	365046.Rta_03740	2.055e-116	381.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria,4AAND@80864|Comamonadaceae	28216|Betaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
ZZS3_k127_7191490_7	365046.Rta_03750	1.014e-103	341.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,4AB2H@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM LemA family protein	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS3_k127_7191490_9	365046.Rta_03760	8.91e-88	302.0	COG0702@1|root,COG0702@2|Bacteria,1RA22@1224|Proteobacteria,2VS8D@28216|Betaproteobacteria,4ADRQ@80864|Comamonadaceae	28216|Betaproteobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7191490_12	365046.Rta_03770	3.176e-72	246.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,4AE1B@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
ZZS3_k127_7191490_2	614083.AWQR01000054_gene1946	5.171e-147	474.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,4AAFQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	hydrolase of the alpha	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
ZZS3_k127_7191490_0	365046.Rta_03810	0.0	1092.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,4AAEW@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
ZZS3_k127_7191490_11	365046.Rta_03820	2.682e-81	273.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,4ADKP@80864|Comamonadaceae	28216|Betaproteobacteria	M	shape-determining protein	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
ZZS3_k127_7191490_10	365046.Rta_03830	1.147e-83	280.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,4AAIN@80864|Comamonadaceae	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
ZZS3_k127_7204507_3	1095769.CAHF01000014_gene3013	3.428e-181	572.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,472RU@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
ZZS3_k127_7204507_6	365046.Rta_07850	2.181e-111	366.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,4ABP2@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB_2	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
ZZS3_k127_7204507_5	543728.Vapar_1128	3.505e-118	390.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,4AC08@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB1	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
ZZS3_k127_7204507_4	1458275.AZ34_00945	1.996e-139	460.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2VJ9I@28216|Betaproteobacteria,4AAZ7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_7204507_7	365046.Rta_07870	1.458e-105	356.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,4AAS4@80864|Comamonadaceae	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
ZZS3_k127_7204507_9	614083.AWQR01000029_gene2067	2.482e-86	293.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,4AA3N@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_7204507_0	365046.Rta_07890	0.0	1024.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,4A9PN@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM ResB family protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
ZZS3_k127_7204507_1	365046.Rta_07900	5.837e-238	776.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,4AC50@80864|Comamonadaceae	28216|Betaproteobacteria	O	Cytochrome C assembly protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
ZZS3_k127_7204507_2	365046.Rta_07910	9.589e-188	589.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,4A9NK@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
ZZS3_k127_7204507_8	365046.Rta_07920	1.165e-94	329.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,4AC09@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
ZZS3_k127_7242575_6	596154.Alide2_2431	5.972e-05	45.0	COG3181@1|root,COG3181@2|Bacteria,1NS37@1224|Proteobacteria,2W061@28216|Betaproteobacteria,4AHAE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7242575_2	338969.Rfer_4003	8.78e-72	253.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria,4AB02@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
ZZS3_k127_7242575_5	748280.NH8B_1847	1.381e-14	81.0	2B3U0@1|root,30SI8@2|Bacteria,1REYA@1224|Proteobacteria,2VRTU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7242575_4	365046.Rta_18120	9.91e-31	135.0	2E1BI@1|root,32WRE@2|Bacteria,1N0CK@1224|Proteobacteria,2VURG@28216|Betaproteobacteria,4AEX5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7242575_1	1268622.AVS7_03878	1.361e-146	466.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,4A9QD@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
ZZS3_k127_7242575_0	365046.Rta_18100	6.714e-214	676.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,4AB32@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_7242575_3	365046.Rta_18090	9.585e-70	237.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,4AB6G@80864|Comamonadaceae	28216|Betaproteobacteria	I	Poly(R)-hydroxyalkanoic acid synthase, class I	phbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
ZZS3_k127_7259961_7	358220.C380_03335	5.504e-91	309.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VJHH@28216|Betaproteobacteria,4AC5B@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	-	-	6.4.1.4,6.4.1.5	ko:K01968,ko:K13777	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
ZZS3_k127_7259961_4	1100720.ALKN01000007_gene3056	2.385e-171	561.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VJ7Q@28216|Betaproteobacteria,4AC45@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_7259961_9	296591.Bpro_3919	5.748e-70	251.0	COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,2VQ8W@28216|Betaproteobacteria,4ADFV@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_7259961_8	76114.ebA2092	6.864e-73	278.0	COG1703@1|root,COG1975@1|root,COG1703@2|Bacteria,COG1975@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,2KVDF@206389|Rhodocyclales	28216|Betaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
ZZS3_k127_7259961_1	110319.CF8_0950	5.631e-238	747.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4DPNX@85009|Propionibacteriales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
ZZS3_k127_7259961_12	1354722.JQLS01000004_gene4224	1.25e-50	185.0	COG2185@1|root,COG2185@2|Bacteria,1NVW6@1224|Proteobacteria,2US8B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	B12 binding domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
ZZS3_k127_7259961_14	1354722.JQLS01000004_gene4225	1.382e-46	175.0	COG1309@1|root,COG1309@2|Bacteria,1N2QP@1224|Proteobacteria,2UD2J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_7259961_16	375286.mma_0873	1.366e-23	102.0	2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,47552@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7259961_5	365046.Rta_07220	2.896e-169	541.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,4ABP9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Luciferase family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
ZZS3_k127_7259961_11	1269813.ATUL01000028_gene2681	3.937e-53	214.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WXZE@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,HAMP,HATPase_c,HisKA,Response_reg
ZZS3_k127_7259961_17	365044.Pnap_2091	9.133e-14	72.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
ZZS3_k127_7259961_6	365046.Rta_09290	2.721e-123	432.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS3_k127_7259961_2	358220.C380_03380	1.874e-204	641.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,4ACGH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_7259961_3	543728.Vapar_4935	2.668e-203	638.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,4ACGH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_7259961_0	358220.C380_03385	0.0	1064.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,4A9UR@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
ZZS3_k127_7259961_10	1223521.BBJX01000006_gene1776	1.637e-66	227.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNC@28216|Betaproteobacteria,4ABEP@80864|Comamonadaceae	28216|Betaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_7287498_10	365046.Rta_35170	8.287e-09	57.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,4AA60@80864|Comamonadaceae	28216|Betaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
ZZS3_k127_7287498_5	1157708.KB907452_gene3916	9.279e-151	514.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,4AD8V@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
ZZS3_k127_7287498_0	358220.C380_04005	0.0	1097.0	COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,2VI17@28216|Betaproteobacteria,4ACCU@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
ZZS3_k127_7287498_3	543728.Vapar_1097	3.786e-187	590.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria,4ADEB@80864|Comamonadaceae	28216|Betaproteobacteria	P	extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
ZZS3_k127_7287498_1	365046.Rta_35180	2.982e-263	816.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,4ACPE@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
ZZS3_k127_7287498_8	1219031.BBJR01000038_gene3071	8.446e-104	346.0	COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,2VPB0@28216|Betaproteobacteria,4AD1Z@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
ZZS3_k127_7287498_7	365046.Rta_35200	2.34e-118	381.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,4ABCC@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
ZZS3_k127_7287498_9	365046.Rta_35200	5.561e-73	252.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,4ABCC@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
ZZS3_k127_7287498_2	365046.Rta_35210	2.255e-192	603.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,4ACNQ@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
ZZS3_k127_7287498_4	365046.Rta_35220	1.365e-164	521.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VIN2@28216|Betaproteobacteria,4ACQ7@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
ZZS3_k127_7287498_6	296591.Bpro_2113	3.112e-145	463.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,4ABBW@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_7292595_8	365046.Rta_16310	2.922e-13	72.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2W2Z1@28216|Betaproteobacteria,4AI91@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_7292595_7	595537.Varpa_3079	1.369e-17	85.0	COG0484@1|root,COG0484@2|Bacteria,1NGV8@1224|Proteobacteria,2VXVF@28216|Betaproteobacteria,4AFUS@80864|Comamonadaceae	28216|Betaproteobacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7292595_4	365046.Rta_16290	8.953e-114	388.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VNFE@28216|Betaproteobacteria,4ABZE@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_7292595_2	365046.Rta_16270	2.135e-168	535.0	COG3181@1|root,COG3181@2|Bacteria,1PZK3@1224|Proteobacteria,2VJ65@28216|Betaproteobacteria,4ABJ7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7292595_1	296591.Bpro_2753	1.33e-216	691.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VI9Q@28216|Betaproteobacteria,4ADCR@80864|Comamonadaceae	28216|Betaproteobacteria	E	Aminotransferase class-V	sgaA	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ZZS3_k127_7292595_5	296591.Bpro_2754	1.557e-102	359.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2VNZS@28216|Betaproteobacteria,4ABT8@80864|Comamonadaceae	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_7292595_0	296591.Bpro_2755	0.0	1610.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,4ABUZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
ZZS3_k127_7292595_6	365046.Rta_16230	1.973e-67	232.0	COG0454@1|root,COG0456@2|Bacteria,1MZUT@1224|Proteobacteria,2VS6B@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_7292595_3	1500894.JQNN01000001_gene1150	2.495e-115	400.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2WGNE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_7324978_5	296591.Bpro_3598	2.71e-104	340.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,4AA24@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
ZZS3_k127_7324978_2	1123504.JQKD01000022_gene143	3.667e-158	505.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,4AAAQ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS3_k127_7324978_6	365046.Rta_28040	8.761e-43	171.0	2B0SP@1|root,31T51@2|Bacteria,1RFNM@1224|Proteobacteria,2VRSS@28216|Betaproteobacteria,4AEGF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Signal peptide protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7324978_0	420662.Mpe_A1363	0.0	1504.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,2VHT2@28216|Betaproteobacteria,1KJ93@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
ZZS3_k127_7324978_3	365046.Rta_28000	2.785e-157	501.0	COG1133@1|root,COG1133@2|Bacteria,1QU39@1224|Proteobacteria,2WHJG@28216|Betaproteobacteria,4AJYG@80864|Comamonadaceae	28216|Betaproteobacteria	I	ABC transporter transmembrane region 2	-	-	-	ko:K17938	-	-	-	-	ko00000,ko02000	9.A.18.1	-	-	SbmA_BacA
ZZS3_k127_7324978_4	365046.Rta_27990	6.62e-120	391.0	COG1167@1|root,COG1396@1|root,COG1167@2|Bacteria,COG1396@2|Bacteria,1MWUC@1224|Proteobacteria,2VHIE@28216|Betaproteobacteria,4AB2F@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
ZZS3_k127_7324978_7	397945.Aave_2213	1.859e-19	97.0	2CAC8@1|root,32RR5@2|Bacteria,1R3EI@1224|Proteobacteria,2VUER@28216|Betaproteobacteria,4AF3F@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7324978_1	864051.BurJ1DRAFT_2068	4.764e-173	556.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,1KJ6I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ZZS3_k127_7335453_11	795666.MW7_0697	4.745e-30	127.0	2ECI6@1|root,32W6D@2|Bacteria,1N4WJ@1224|Proteobacteria,2VVDB@28216|Betaproteobacteria,1K5V4@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7335453_9	760117.JN27_06950	7.293e-121	400.0	COG2771@1|root,COG2771@2|Bacteria,1RK9I@1224|Proteobacteria,2WAN8@28216|Betaproteobacteria,47840@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ZZS3_k127_7335453_0	296591.Bpro_2925	2.849e-233	731.0	COG0557@1|root,COG0557@2|Bacteria,1NI95@1224|Proteobacteria,2VNKE@28216|Betaproteobacteria,4AA79@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
ZZS3_k127_7335453_2	365046.Rta_29400	3.778e-222	693.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VIP6@28216|Betaproteobacteria,4ABUR@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_7335453_5	365046.Rta_29390	4.729e-146	471.0	COG1304@1|root,COG2301@1|root,COG1304@2|Bacteria,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2VKG1@28216|Betaproteobacteria,4AC4D@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS3_k127_7335453_1	365046.Rta_29390	1.154e-226	706.0	COG1304@1|root,COG2301@1|root,COG1304@2|Bacteria,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2VKG1@28216|Betaproteobacteria,4AC4D@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS3_k127_7335453_4	365046.Rta_29380	9.806e-173	566.0	COG3181@1|root,COG3181@2|Bacteria,1R6S3@1224|Proteobacteria,2VHD5@28216|Betaproteobacteria,4AADY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7335453_6	1268622.AVS7_01489	6.374e-138	447.0	COG3181@1|root,COG3181@2|Bacteria,1NQBH@1224|Proteobacteria,2VN1G@28216|Betaproteobacteria,4ABVS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7335453_10	196367.JNFG01000199_gene3591	1.374e-93	317.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,2VR2C@28216|Betaproteobacteria,1KBYM@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ZZS3_k127_7335453_8	398578.Daci_1381	3.083e-121	397.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2WHP1@28216|Betaproteobacteria,4ACYE@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_7335453_7	1268622.AVS7_01492	1.736e-131	435.0	COG0583@1|root,COG0583@2|Bacteria,1RBNC@1224|Proteobacteria,2VIB8@28216|Betaproteobacteria,4AE44@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7335453_3	384765.SIAM614_29406	1.452e-215	683.0	COG0405@1|root,COG0405@2|Bacteria,1MXXD@1224|Proteobacteria,2TSB2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Gamma-glutamyltransferase	MA20_09815	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS3_k127_7335453_12	1054213.HMPREF9946_00762	1.421e-25	106.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TT4C@28211|Alphaproteobacteria,2JW5B@204441|Rhodospirillales	204441|Rhodospirillales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ZZS3_k127_7434665_1	477184.KYC_22211	1.671e-195	612.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2VK18@28216|Betaproteobacteria,3T3W8@506|Alcaligenaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_7434665_6	1038860.AXAP01000002_gene4910	7.356e-82	286.0	COG0179@1|root,COG0179@2|Bacteria,1NTUI@1224|Proteobacteria,2U2F5@28211|Alphaproteobacteria,3K3PJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_7434665_5	477184.KYC_22221	1.115e-111	371.0	COG0111@1|root,COG0111@2|Bacteria,1RAVY@1224|Proteobacteria,2WCG1@28216|Betaproteobacteria,3T6IV@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_7434665_2	477184.KYC_22226	2.768e-188	595.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2W1P7@28216|Betaproteobacteria,3T1ZA@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_7434665_0	264198.Reut_C5897	5.257e-209	654.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2VZ73@28216|Betaproteobacteria,1K4ND@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_7434665_4	264198.Reut_C5896	1.038e-130	437.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VZDY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7434665_3	1007105.PT7_3459	7.031e-173	550.0	COG4948@1|root,COG4948@2|Bacteria,1MXK7@1224|Proteobacteria,2W2PC@28216|Betaproteobacteria,3T7TM@506|Alcaligenaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_7434665_7	745310.G432_06405	4.947e-55	213.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2K3ZJ@204457|Sphingomonadales	204457|Sphingomonadales	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
ZZS3_k127_7463584_6	614083.AWQR01000006_gene329	5.787e-18	86.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VKEQ@28216|Betaproteobacteria,4AAFG@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HisKA,PAS_4
ZZS3_k127_7463584_2	338969.Rfer_0729	2.163e-138	446.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,4AAC1@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
ZZS3_k127_7463584_4	1123255.JHYS01000005_gene770	5.329e-61	230.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,4AE0X@80864|Comamonadaceae	28216|Betaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
ZZS3_k127_7463584_5	296591.Bpro_4096	5.705e-59	223.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,4AE4I@80864|Comamonadaceae	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
ZZS3_k127_7463584_1	365046.Rta_07110	1.656e-166	546.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,4ABCR@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM PhoH family protein	ybeZ	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
ZZS3_k127_7463584_3	365046.Rta_07120	2.53e-86	307.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,4AAIH@80864|Comamonadaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
ZZS3_k127_7463584_0	1265502.KB905948_gene985	8.12e-177	558.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,4A9VT@80864|Comamonadaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
ZZS3_k127_7508629_10	338969.Rfer_3502	6.451e-19	90.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNC@28216|Betaproteobacteria,4ABEP@80864|Comamonadaceae	28216|Betaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_7508629_4	614083.AWQR01000001_gene3117	3.098e-125	435.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJRS@28216|Betaproteobacteria,4AAWC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_7508629_1	338969.Rfer_3500	1e-179	567.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VKYI@28216|Betaproteobacteria,4A9Y9@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_7508629_3	338969.Rfer_3499	7.084e-148	486.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VNQX@28216|Betaproteobacteria,4AC0P@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_7508629_5	614083.AWQR01000001_gene3120	2.978e-121	394.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2VNIR@28216|Betaproteobacteria,4AA8H@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS3_k127_7508629_6	535289.Dtpsy_0580	1.136e-63	221.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,4AE0U@80864|Comamonadaceae	28216|Betaproteobacteria	I	Thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
ZZS3_k127_7508629_0	1268622.AVS7_00086	1.397e-312	968.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,4AAVU@80864|Comamonadaceae	28216|Betaproteobacteria	V	ABC transporter, transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS3_k127_7508629_11	543728.Vapar_5315	1.204e-18	102.0	2CE4Y@1|root,34C4Z@2|Bacteria,1P3HD@1224|Proteobacteria,2W4H6@28216|Betaproteobacteria,4AI8C@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7508629_2	887062.HGR_08139	1.25e-155	502.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,2VMJE@28216|Betaproteobacteria,4AC93@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_7508629_7	443152.MDG893_16057	3.02e-61	214.0	COG0346@1|root,COG0346@2|Bacteria,1RI3Q@1224|Proteobacteria,1S6F6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_7508629_8	760117.JN27_04995	6.505e-60	210.0	COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,2VT3X@28216|Betaproteobacteria,477KF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
ZZS3_k127_7508629_9	1122604.JONR01000022_gene657	2.151e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria,1X75K@135614|Xanthomonadales	135614|Xanthomonadales	E	Lactoylglutathione lyase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_7532306_0	365046.Rta_28440	1.393e-300	924.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,4AAZS@80864|Comamonadaceae	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
ZZS3_k127_7532306_2	365046.Rta_28450	6.416e-233	730.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4ABID@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_7532306_8	365046.Rta_28460	2.148e-139	462.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,4ACWA@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM MucB RseB family protein	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
ZZS3_k127_7532306_18	338969.Rfer_1737	1.758e-30	131.0	COG3073@1|root,COG3073@2|Bacteria,1N3E9@1224|Proteobacteria,2VUN0@28216|Betaproteobacteria,4AEWZ@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM Anti sigma-E protein RseA family protein	-	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
ZZS3_k127_7532306_11	365046.Rta_28480	6.986e-106	354.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,4AA53@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_7532306_20	338969.Rfer_1735	4.309e-26	113.0	2EBNT@1|root,335P0@2|Bacteria,1NDZY@1224|Proteobacteria,2VWU2@28216|Betaproteobacteria,4AFEY@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7532306_1	1123504.JQKD01000022_gene102	4.563e-234	727.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,4AAA2@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS3_k127_7532306_17	1123504.JQKD01000022_gene101	6.078e-34	144.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,4AF2T@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS3_k127_7532306_9	365046.Rta_28520	2.277e-121	410.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,4A9NU@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_7532306_6	365046.Rta_28530	8.532e-146	486.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,4ABM8@80864|Comamonadaceae	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
ZZS3_k127_7532306_4	365046.Rta_28540	2.894e-177	560.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,4AAUT@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS3_k127_7532306_3	365046.Rta_28550	4.329e-182	576.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,4A9V1@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
ZZS3_k127_7532306_19	365046.Rta_28560	5.278e-29	127.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,4AFGS@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
ZZS3_k127_7532306_16	365046.Rta_28570	2.92e-61	217.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,4AEE2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
ZZS3_k127_7532306_13	365046.Rta_28580	5.148e-91	302.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,4ABNK@80864|Comamonadaceae	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
ZZS3_k127_7532306_12	232721.Ajs_3285	8.839e-105	347.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,4AAHJ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_2	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
ZZS3_k127_7532306_14	1100720.ALKN01000045_gene442	1.318e-66	231.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,2VR2C@28216|Betaproteobacteria,4AE4U@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
ZZS3_k127_7532306_7	365046.Rta_28600	1.92e-143	468.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,4ABX3@80864|Comamonadaceae	28216|Betaproteobacteria	OU	peptidase S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
ZZS3_k127_7532306_15	1100720.ALKN01000035_gene922	1.008e-64	230.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,4AER9@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rieske 2Fe-2S domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
ZZS3_k127_7532306_22	1157708.KB907452_gene3713	1.093e-16	91.0	2DR05@1|root,339MI@2|Bacteria,1NHD4@1224|Proteobacteria,2VYAF@28216|Betaproteobacteria,4AG2U@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase inhibitor I78 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I78
ZZS3_k127_7532306_10	365046.Rta_28620	7.172e-112	366.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,4ABA7@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_7532306_5	535289.Dtpsy_2642	6.31e-160	513.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,4AA5K@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS3_k127_7532306_21	1458275.AZ34_06665	2.805e-18	84.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,4ABMR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
ZZS3_k127_7539125_11	398578.Daci_3899	7.872e-19	89.0	COG0551@1|root,COG1787@1|root,COG0551@2|Bacteria,COG1787@2|Bacteria,1RAHG@1224|Proteobacteria,2VNZE@28216|Betaproteobacteria,4AC2P@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat,zf-C4_Topoisom
ZZS3_k127_7539125_8	1122962.AULH01000020_gene3638	2.158e-35	138.0	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,2UV1A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
ZZS3_k127_7539125_6	381666.H16_B2137	1.885e-37	144.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,2VUPS@28216|Betaproteobacteria,1K8ZU@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_7539125_4	381666.H16_B2136	2.365e-51	194.0	COG3832@1|root,COG3832@2|Bacteria,1RF9V@1224|Proteobacteria,2W2D0@28216|Betaproteobacteria,1KGAT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_7539125_5	745411.B3C1_13968	1.062e-41	160.0	COG3832@1|root,COG3832@2|Bacteria,1RJ9N@1224|Proteobacteria,1S5RD@1236|Gammaproteobacteria,1JBDI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_7539125_1	543728.Vapar_4609	3.675e-125	408.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,4AK38@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
ZZS3_k127_7539125_7	570967.JMLV01000002_gene1604	5.368e-37	157.0	COG2044@1|root,COG2044@2|Bacteria,1RGAZ@1224|Proteobacteria,2UBFX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
ZZS3_k127_7539125_10	1192124.LIG30_2335	4.038e-20	101.0	2DW9X@1|root,33Z82@2|Bacteria,1R2UF@1224|Proteobacteria,2WID8@28216|Betaproteobacteria,1KB81@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7539125_3	365046.Rta_27430	1.523e-78	280.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2VQYD@28216|Betaproteobacteria,4AE74@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,NTP_transf_2
ZZS3_k127_7539125_0	365046.Rta_27380	2.372e-210	659.0	COG0075@1|root,COG0075@2|Bacteria,1PM38@1224|Proteobacteria,2VHNM@28216|Betaproteobacteria,4AAG6@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS3_k127_7539125_12	365046.Rta_27170	7.779e-12	66.0	2DSFF@1|root,33FYB@2|Bacteria,1NHKC@1224|Proteobacteria,2VY54@28216|Betaproteobacteria,4AFUZ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7539125_2	365046.Rta_27500	2.388e-96	322.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,2VPRF@28216|Betaproteobacteria,4AEQ9@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	ko:K05372	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
ZZS3_k127_7588463_1	296591.Bpro_3245	1.575e-262	814.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,4A9X6@80864|Comamonadaceae	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
ZZS3_k127_7588463_0	365046.Rta_26310	5.864e-288	888.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,4AAN9@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
ZZS3_k127_7588463_3	365046.Rta_26300	1.072e-241	754.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,4AAI5@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS3_k127_7588463_8	1123504.JQKD01000023_gene175	1.441e-32	145.0	2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,2VVR9@28216|Betaproteobacteria,4AF0J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2818)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2818
ZZS3_k127_7588463_6	595537.Varpa_4010	1.855e-79	270.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,4AD0S@80864|Comamonadaceae	28216|Betaproteobacteria	L	Nudix hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
ZZS3_k127_7588463_7	365046.Rta_26270	8.069e-59	216.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,4AECI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
ZZS3_k127_7588463_2	365046.Rta_26260	1.665e-260	850.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,4AARD@80864|Comamonadaceae	28216|Betaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS3_k127_7588463_5	296591.Bpro_4035	1.323e-118	414.0	COG0583@1|root,COG0583@2|Bacteria,1R4IG@1224|Proteobacteria,2VKR4@28216|Betaproteobacteria,4AHK1@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7588463_4	365044.Pnap_3505	1.749e-211	662.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,4AAPD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	frc_13	-	2.8.3.16,2.8.3.22	ko:K07749,ko:K14471,ko:K14472	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R00406,R03154	RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
ZZS3_k127_768186_6	1165096.ARWF01000001_gene1008	3.873e-33	134.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,2VWQY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
ZZS3_k127_768186_9	1122951.ATUE01000009_gene421	2.281e-14	79.0	COG5430@1|root,COG5430@2|Bacteria	2|Bacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
ZZS3_k127_768186_7	1144343.PMI41_03475	6.006e-31	141.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,2TU95@28211|Alphaproteobacteria,43MMM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	NU	P pilus assembly protein porin PapC	-	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	PapC_C,Usher
ZZS3_k127_768186_5	338963.Pcar_2058	2.577e-40	165.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
ZZS3_k127_768186_3	365046.Rta_34840	8.947e-119	385.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VQCD@28216|Betaproteobacteria,4AJ3G@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_768186_1	365046.Rta_34830	7.514e-163	534.0	COG5002@1|root,COG5002@2|Bacteria,1QTSA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484,ko:K07644,ko:K07645	ko02020,ko02024,map02020,map02024	M00452,M00453,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
ZZS3_k127_768186_8	358220.C380_13005	4.803e-19	89.0	2C8WJ@1|root,2ZQBS@2|Bacteria,1PBQT@1224|Proteobacteria,2W52E@28216|Betaproteobacteria,4AINX@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4148
ZZS3_k127_768186_0	535289.Dtpsy_0466	0.0	1043.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,4AADZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
ZZS3_k127_768186_4	365046.Rta_34800	1.042e-57	220.0	COG0725@1|root,COG0725@2|Bacteria,1NY9R@1224|Proteobacteria,2VRYF@28216|Betaproteobacteria,4ADYN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
ZZS3_k127_768186_2	365046.Rta_34790	2.25e-155	493.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPME@28216|Betaproteobacteria,4ADEN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7689930_4	1003200.AXXA_11580	1.315e-74	264.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKDI@28216|Betaproteobacteria,3T2HK@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_7689930_6	1280947.HY30_15920	3.115e-54	212.0	2ECXI@1|root,336UR@2|Bacteria,1N6ZV@1224|Proteobacteria,2UXEV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7689930_1	1429916.X566_11925	4.514e-168	555.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TRM9@28211|Alphaproteobacteria,3K3KQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
ZZS3_k127_7689930_0	1532557.JL37_25265	1.82e-180	588.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VM1E@28216|Betaproteobacteria,3T2D5@506|Alcaligenaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_7689930_7	1429916.X566_11920	3.283e-28	130.0	COG1414@1|root,COG1414@2|Bacteria,1R883@1224|Proteobacteria,2U2RC@28211|Alphaproteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_7689930_3	1007105.PT7_2672	2.378e-89	319.0	COG1024@1|root,COG1024@2|Bacteria,1PETC@1224|Proteobacteria,2W8XP@28216|Betaproteobacteria,3T6WI@506|Alcaligenaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_7689930_2	1545915.JROG01000004_gene2137	3.321e-127	432.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2TZDG@28211|Alphaproteobacteria,2K2PK@204457|Sphingomonadales	204457|Sphingomonadales	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
ZZS3_k127_7689930_5	298655.KI912266_gene677	6.442e-67	238.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS3_k127_7689930_8	1265502.KB905932_gene1903	7.603e-18	85.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
ZZS3_k127_7698979_4	365046.Rta_25210	1.177e-86	287.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,4A9SJ@80864|Comamonadaceae	28216|Betaproteobacteria	BQ	PFAM histone deacetylase superfamily	hdaH	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
ZZS3_k127_7698979_3	398578.Daci_2388	8.737e-109	357.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,4ACSW@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_7698979_2	1157708.KB907456_gene2499	4.505e-141	464.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,4AA28@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
ZZS3_k127_7698979_0	1100721.ALKO01000021_gene587	4.141e-218	685.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ZZS3_k127_7698979_5	1100721.ALKO01000021_gene586	1.724e-58	209.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
ZZS3_k127_7698979_1	1100721.ALKO01000021_gene585	7.551e-152	490.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VP2F@28216|Betaproteobacteria,4AJA7@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ZZS3_k127_7698979_6	358220.C380_17285	2.417e-27	115.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,4ABCD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
ZZS3_k127_7769425_5	1268622.AVS7_03545	2.678e-58	204.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9V8@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator	yfhA	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_7769425_4	365046.Rta_34420	4.738e-59	208.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9V8@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator	yfhA	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_7769425_7	365046.Rta_34410	1.178e-30	128.0	2CKA9@1|root,32SBY@2|Bacteria,1N3MW@1224|Proteobacteria,2VU1K@28216|Betaproteobacteria,4AEZJ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7769425_1	365046.Rta_34400	3.381e-184	586.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,4A9R9@80864|Comamonadaceae	28216|Betaproteobacteria	T	Signal transduction histidine kinase	yfhK	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
ZZS3_k127_7769425_0	1265502.KB905933_gene2009	2.743e-254	790.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,4ABG0@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
ZZS3_k127_7769425_6	365046.Rta_34380	5.064e-36	141.0	2EEJ7@1|root,338D7@2|Bacteria,1NCQP@1224|Proteobacteria,2VWTW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7769425_2	420662.Mpe_A0106	6.831e-128	426.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria	1224|Proteobacteria	S	Von willebrand factor, type a	-	-	-	-	-	-	-	-	-	-	-	-	VWA
ZZS3_k127_7769425_3	543728.Vapar_4648	2.403e-77	263.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria,4AFBS@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS3_k127_7769425_8	864051.BurJ1DRAFT_4929	6.455e-11	73.0	2ERJY@1|root,33J5F@2|Bacteria,1NHP2@1224|Proteobacteria,2VYEB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7789935_3	365044.Pnap_0012	8.316e-19	101.0	COG0392@1|root,COG0392@2|Bacteria,1MXH9@1224|Proteobacteria,2VKP8@28216|Betaproteobacteria,4AB78@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	ybhN	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS3_k127_7789935_0	365046.Rta_00420	4.174e-187	617.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,4AC66@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_7789935_1	1207076.ALAT01000143_gene569	6.879e-109	359.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,1RNSP@1236|Gammaproteobacteria,1Z076@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Endonuclease Exonuclease phosphatase	ybhP	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS3_k127_7789935_2	365046.Rta_00440	2.681e-43	166.0	COG3637@1|root,COG3637@2|Bacteria,1N7IC@1224|Proteobacteria,2VVZ0@28216|Betaproteobacteria,4AES8@80864|Comamonadaceae	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PagL
ZZS3_k127_7791513_7	365046.Rta_32700	4.656e-103	354.0	COG1116@1|root,COG1116@2|Bacteria,1P4HB@1224|Proteobacteria,2VISQ@28216|Betaproteobacteria,4A9SC@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
ZZS3_k127_7791513_3	358220.C380_05335	1.221e-174	556.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2VIMG@28216|Betaproteobacteria,4AD5J@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
ZZS3_k127_7791513_10	365046.Rta_32680	2.065e-41	155.0	COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2VWCP@28216|Betaproteobacteria,4AINA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
ZZS3_k127_7791513_0	1504672.669786038	0.0	1241.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,4AA5S@80864|Comamonadaceae	28216|Betaproteobacteria	C	Phosphate acetyl butaryl transferase	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
ZZS3_k127_7791513_5	395495.Lcho_1123	1.347e-128	422.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,1KJ4G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	2-hydroxy-3-oxopropionate reductase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_7791513_6	1458275.AZ34_05095	3.307e-113	396.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,4ABCT@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the hyi family	hfi	-	5.3.1.22,5.3.1.35	ko:K01816,ko:K22131	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
ZZS3_k127_7791513_1	1458275.AZ34_05100	0.0	1016.0	COG3960@1|root,COG3960@2|Bacteria,1MV88@1224|Proteobacteria,2VHT9@28216|Betaproteobacteria,4A9Q1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the TPP enzyme family	gcl	-	4.1.1.47	ko:K01608	ko00630,ko01100,map00630,map01100	-	R00013	RC00899	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_7791513_9	1504672.669786061	9.29e-45	166.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,2VTP9@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_7791513_2	296591.Bpro_0212	3.23e-197	649.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1NC9X@1224|Proteobacteria,2WHF9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS3_k127_7791513_11	215803.DB30_7268	0.0003026	49.0	COG0745@1|root,COG2199@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria,2YUZ7@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
ZZS3_k127_7791513_8	296591.Bpro_4464	1.898e-72	254.0	COG0745@1|root,COG0745@2|Bacteria,1R7VB@1224|Proteobacteria,2VI0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
ZZS3_k127_7791513_4	1458275.AZ34_05105	2.43e-146	468.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VIZP@28216|Betaproteobacteria,4A9RC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_7791621_2	1157708.KB907457_gene2552	1.853e-227	709.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2VIB6@28216|Betaproteobacteria,4ACZX@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fcs	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
ZZS3_k127_7791621_6	358220.C380_01275	1.016e-124	424.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2VIYH@28216|Betaproteobacteria,4AAXH@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS3_k127_7791621_5	1157708.KB907457_gene2554	1.032e-157	506.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,4ACT4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_7791621_4	1286631.X805_11570	3.501e-159	509.0	COG0559@1|root,COG0559@2|Bacteria,1MXMC@1224|Proteobacteria,2VJ1Y@28216|Betaproteobacteria,1KKBR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_7791621_0	864051.BurJ1DRAFT_3922	6.114e-298	936.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,1KKAU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
ZZS3_k127_7791621_7	864051.BurJ1DRAFT_3921	7.603e-114	372.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,1KJM2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_7791621_10	365046.Rta_25030	3.169e-61	226.0	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VTDX@28216|Betaproteobacteria,4ADXM@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_7791621_11	1219031.BBJR01000041_gene2972	1.844e-48	176.0	COG1733@1|root,COG1733@2|Bacteria,1N0WG@1224|Proteobacteria,2VSZA@28216|Betaproteobacteria,4AEFT@80864|Comamonadaceae	28216|Betaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HxlR
ZZS3_k127_7791621_3	365046.Rta_25050	1.856e-181	582.0	COG3970@1|root,COG3970@2|Bacteria,1MVA2@1224|Proteobacteria,2VIXV@28216|Betaproteobacteria,4AC05@80864|Comamonadaceae	28216|Betaproteobacteria	S	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_7791621_9	365046.Rta_25060	5.303e-62	215.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,4AEH2@80864|Comamonadaceae	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
ZZS3_k127_7791621_8	1100721.ALKO01000021_gene572	1.719e-67	235.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,4ADJI@80864|Comamonadaceae	28216|Betaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
ZZS3_k127_7791621_1	864051.BurJ1DRAFT_2907	3.337e-229	713.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,1KKDN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ZZS3_k127_779854_1	365046.Rta_30780	2.222e-174	550.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,4ABTM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ZZS3_k127_779854_3	365046.Rta_30770	7.61e-140	447.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,4AAD1@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
ZZS3_k127_779854_8	358220.C380_19120	2.58e-52	190.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,4AEDM@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
ZZS3_k127_779854_9	365046.Rta_30750	1.773e-43	159.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,4AEY1@80864|Comamonadaceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
ZZS3_k127_779854_6	358220.C380_19130	1.09e-73	251.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,4ADSB@80864|Comamonadaceae	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
ZZS3_k127_779854_2	595537.Varpa_4766	1.675e-141	459.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,4ABQ0@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
ZZS3_k127_779854_5	365046.Rta_30720	1.996e-97	323.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2VQ6Y@28216|Betaproteobacteria,4ADNP@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_779854_10	1097668.BYI23_B012100	2.151e-41	158.0	COG0526@1|root,COG0526@2|Bacteria,1MZ6D@1224|Proteobacteria,2VU4B@28216|Betaproteobacteria,1K8QX@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ZZS3_k127_779854_7	1157708.KB907470_gene238	6.802e-58	210.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VVH4@28216|Betaproteobacteria,4AEZV@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_779854_4	1276756.AUEX01000001_gene1096	1.583e-132	437.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,4ABR7@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
ZZS3_k127_779854_0	365046.Rta_30690	5.58e-208	666.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,4A9N9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
ZZS3_k127_785266_0	365046.Rta_01390	4.425e-292	900.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,4AB6P@80864|Comamonadaceae	28216|Betaproteobacteria	H	Methionine synthase B12-binding module cap domain protein	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
ZZS3_k127_785266_17	365046.Rta_01400	2.286e-48	179.0	COG3133@1|root,COG3133@2|Bacteria,1NDPC@1224|Proteobacteria,2VX7D@28216|Betaproteobacteria,4AFZT@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
ZZS3_k127_785266_7	365046.Rta_01410	1.807e-112	372.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria,4ABXQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ZZS3_k127_785266_5	1123504.JQKD01000009_gene2197	2.361e-154	497.0	COG2271@1|root,COG2271@2|Bacteria,1QVKZ@1224|Proteobacteria,2WHHX@28216|Betaproteobacteria,4AJXA@80864|Comamonadaceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_785266_18	742159.HMPREF0004_2312	9.437e-25	121.0	2F71X@1|root,33ZHI@2|Bacteria,1NXWU@1224|Proteobacteria,2W8AE@28216|Betaproteobacteria,3T4Z2@506|Alcaligenaceae	28216|Betaproteobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
ZZS3_k127_785266_1	1532557.JL37_06255	9.762e-291	917.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2W1AU@28216|Betaproteobacteria,3T61F@506|Alcaligenaceae	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ZZS3_k127_785266_8	1003200.AXXA_18887	3.809e-106	361.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VZXY@28216|Betaproteobacteria,3T76J@506|Alcaligenaceae	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ZZS3_k127_785266_9	1216976.AX27061_1772	8.799e-102	338.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VJN5@28216|Betaproteobacteria,3T65U@506|Alcaligenaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ZZS3_k127_785266_10	1156919.QWC_15324	9.431e-97	324.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2W2GA@28216|Betaproteobacteria,3T6FN@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
ZZS3_k127_785266_15	1392838.AWNM01000071_gene551	5.858e-56	201.0	COG1917@1|root,COG1917@2|Bacteria,1RAGP@1224|Proteobacteria,2VYF6@28216|Betaproteobacteria,3T4R6@506|Alcaligenaceae	28216|Betaproteobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
ZZS3_k127_785266_4	762376.AXYL_01888	1.344e-188	596.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2VHXC@28216|Betaproteobacteria,3T37C@506|Alcaligenaceae	28216|Betaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_785266_11	1156919.QWC_15339	1.468e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,1NTGG@1224|Proteobacteria,2WF5A@28216|Betaproteobacteria,3T5GJ@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_785266_12	742159.HMPREF0004_2304	1.953e-83	285.0	COG1414@1|root,COG1414@2|Bacteria,1RDS5@1224|Proteobacteria,2VTD4@28216|Betaproteobacteria,3T6CB@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ZZS3_k127_785266_3	338969.Rfer_0471	7.17e-237	743.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,4ABQJ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Mg chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
ZZS3_k127_785266_6	365046.Rta_01430	9.334e-116	381.0	2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2VSAP@28216|Betaproteobacteria,4AJC5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
ZZS3_k127_785266_14	365046.Rta_01440	1.077e-62	218.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,4AE4W@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
ZZS3_k127_785266_2	365046.Rta_01450	1.53e-248	781.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,4AB9B@80864|Comamonadaceae	28216|Betaproteobacteria	P	ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
ZZS3_k127_785266_16	365046.Rta_01510	9.065e-50	194.0	COG4191@1|root,COG4191@2|Bacteria,1NYMR@1224|Proteobacteria,2W3N9@28216|Betaproteobacteria,4AI1N@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_785266_13	614083.AWQR01000022_gene23	2.205e-79	284.0	COG2017@1|root,COG2017@2|Bacteria,1RGXX@1224|Proteobacteria,2VQB2@28216|Betaproteobacteria,4AJIG@80864|Comamonadaceae	28216|Betaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
ZZS3_k127_819399_7	365046.Rta_31800	8.997e-69	234.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,4ADFI@80864|Comamonadaceae	28216|Betaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
ZZS3_k127_819399_0	365046.Rta_31810	6.351e-273	849.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2VJWM@28216|Betaproteobacteria,4AAPQ@80864|Comamonadaceae	28216|Betaproteobacteria	P	Na Pi-cotransporter II-related protein	nptA	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
ZZS3_k127_819399_8	365046.Rta_31820	5.495e-51	184.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VRW4@28216|Betaproteobacteria,4AE7N@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_819399_2	1100721.ALKO01000021_gene758	4.877e-175	554.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2VH3Z@28216|Betaproteobacteria,4AASJ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_819399_3	365046.Rta_31850	2.666e-138	447.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,4AC3D@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_819399_5	296591.Bpro_3876	1.042e-123	413.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,4ACC2@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_819399_10	358220.C380_06545	3.72e-34	148.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,SH3_3,SH3_4
ZZS3_k127_819399_6	358220.C380_06540	1.808e-107	365.0	COG4784@1|root,COG4784@2|Bacteria,1QXTD@1224|Proteobacteria,2WHJ6@28216|Betaproteobacteria,4AIDE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_819399_4	296591.Bpro_2792	3.643e-127	415.0	COG0179@1|root,COG0179@2|Bacteria,1QUQP@1224|Proteobacteria,2VQEI@28216|Betaproteobacteria,4AF27@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
ZZS3_k127_819399_1	1276756.AUEX01000004_gene2365	2.953e-194	619.0	COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,2VIAD@28216|Betaproteobacteria,4A9Z7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
ZZS3_k127_819399_9	1123504.JQKD01000012_gene1351	2.01e-48	173.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAHM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA4	-	-	-	-	-	-	-	-	-	-	-	TctA
ZZS3_k127_915658_1	365046.Rta_11430	2.639e-275	850.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,4A9Q8@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_915658_7	1265310.CCBD010000062_gene1237	6.269e-49	187.0	COG5579@1|root,COG5579@2|Bacteria,2IM9J@201174|Actinobacteria,239PD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
ZZS3_k127_915658_9	365046.Rta_16770	5.639e-37	146.0	COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,2VJV9@28216|Betaproteobacteria,4AA5W@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
ZZS3_k127_915658_0	365046.Rta_00090	0.0	1028.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,2VN7Y@28216|Betaproteobacteria,4AD8T@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_915658_8	365046.Rta_05790	4.334e-46	171.0	COG1917@1|root,COG1917@2|Bacteria,1NA8I@1224|Proteobacteria,2VVT4@28216|Betaproteobacteria,4AFFI@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_915658_4	1100720.ALKN01000045_gene473	4.528e-99	344.0	COG3181@1|root,COG3181@2|Bacteria,1RCZU@1224|Proteobacteria,2W17E@28216|Betaproteobacteria,4AHKD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ZZS3_k127_915658_2	1100720.ALKN01000045_gene474	1.928e-227	719.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,4AGNX@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_915658_10	365046.Rta_32275	4.805e-33	142.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,2VVVS@28216|Betaproteobacteria,4AF6Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
ZZS3_k127_915658_5	1458275.AZ34_05245	6.84e-76	276.0	COG0262@1|root,COG0262@2|Bacteria,1R6X0@1224|Proteobacteria,2VI26@28216|Betaproteobacteria,4AB69@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS3_k127_915658_6	1366050.N234_26740	1.711e-64	224.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2VRA3@28216|Betaproteobacteria,1K816@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glyoxalase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_915658_11	159087.Daro_1865	3.276e-22	106.0	2EC8Y@1|root,3367B@2|Bacteria,1NFHG@1224|Proteobacteria,2VWKX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_915658_3	596153.Alide_3214	4.706e-211	670.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH1N@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_920268_0	1366050.N234_28190	2.592e-234	732.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2VM0R@28216|Betaproteobacteria,1JZY1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
ZZS3_k127_920268_4	1366050.N234_28185	7.178e-72	245.0	2A74D@1|root,30W03@2|Bacteria,1RBK6@1224|Proteobacteria,2VYUK@28216|Betaproteobacteria,1KB6H@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_920268_2	640511.BC1002_5654	4.211e-107	356.0	COG0583@1|root,COG0583@2|Bacteria,1MV06@1224|Proteobacteria,2VHGD@28216|Betaproteobacteria,1K5DG@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional Regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ZZS3_k127_920268_3	543728.Vapar_0079	1.78e-90	307.0	COG1028@1|root,COG1028@2|Bacteria,1MUWP@1224|Proteobacteria,2VNGU@28216|Betaproteobacteria,4AGPF@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS3_k127_920268_5	375286.mma_0950	5.426e-65	231.0	COG3474@1|root,COG3474@2|Bacteria,1RI3E@1224|Proteobacteria,2WFW7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
ZZS3_k127_920268_1	381666.H16_B0901	4.8e-127	419.0	COG2267@1|root,COG2267@2|Bacteria,1P0FV@1224|Proteobacteria,2VZJF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS3_k127_965479_5	365046.Rta_07380	5.202e-112	365.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,4AB1X@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gst8	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
ZZS3_k127_965479_0	365046.Rta_07360	1.765e-207	651.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,4AAWR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
ZZS3_k127_965479_4	296591.Bpro_4084	4.001e-141	453.0	COG1940@1|root,COG1940@2|Bacteria,1PW32@1224|Proteobacteria,2VN8E@28216|Betaproteobacteria,4AA0M@80864|Comamonadaceae	28216|Betaproteobacteria	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS3_k127_965479_7	365046.Rta_07330	4.247e-26	108.0	2EITT@1|root,33CJ3@2|Bacteria,1NH36@1224|Proteobacteria,2VXT6@28216|Betaproteobacteria,4AFEX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
ZZS3_k127_965479_2	365046.Rta_07320	2.863e-184	599.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2VNI2@28216|Betaproteobacteria,4A9Y0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS3_k127_965479_1	365046.Rta_07310	3.803e-207	646.0	COG1082@1|root,COG1082@2|Bacteria,1MVSJ@1224|Proteobacteria,2VPWX@28216|Betaproteobacteria,4ADC2@80864|Comamonadaceae	28216|Betaproteobacteria	G	AP endonuclease 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
ZZS3_k127_965479_3	365046.Rta_07300	3.69e-174	551.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VIN6@28216|Betaproteobacteria,4A9NA@80864|Comamonadaceae	28216|Betaproteobacteria	G	Periplasmic binding protein domain	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ZZS3_k127_965479_6	1157708.KB907463_gene796	2.738e-110	358.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VKPA@28216|Betaproteobacteria,4A9QB@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
ZZS3_k127_978054_1	1123504.JQKD01000007_gene3296	2.192e-122	396.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2VJ2R@28216|Betaproteobacteria,4AAFU@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
ZZS3_k127_978054_3	1380387.JADM01000007_gene788	1.116e-95	337.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ZZS3_k127_978054_2	1458275.AZ34_03470	3.254e-109	363.0	COG0300@1|root,COG0300@2|Bacteria,1R3VU@1224|Proteobacteria,2VN1U@28216|Betaproteobacteria,4A9T9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_978054_5	1003200.AXXA_22040	5.604e-62	220.0	COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,2VNVW@28216|Betaproteobacteria,3T8A8@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_978054_7	330214.NIDE3684	5.093e-14	85.0	COG3806@1|root,COG3806@2|Bacteria	2|Bacteria	T	Anti-sigma factor	-	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7
ZZS3_k127_978054_6	330214.NIDE1747	5.166e-31	130.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ZZS3_k127_978054_4	864051.BurJ1DRAFT_0690	3.188e-79	269.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,2VR4I@28216|Betaproteobacteria,1KKUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	WLM domain	ygjP	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
ZZS3_k127_978054_0	365046.Rta_04680	4.661e-154	492.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,2VJ0H@28216|Betaproteobacteria,4AB8R@80864|Comamonadaceae	28216|Betaproteobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
## 3559 queries scanned
## Total time (seconds): 37.64157962799072
## Rate: 94.55 q/s