## Mon Nov 11 16:55:42 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/ZZS3_bin.6.fa -m mmseqs --itype genome -o ZZS3_bin.6 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/ZZS3_bin.6 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
ZZS3_k127_1003198_3	945713.IALB_2907	4.373e-49	201.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_1003198_1	1411123.JQNH01000001_gene3173	2.749e-89	306.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2U62M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
ZZS3_k127_1003198_2	1173026.Glo7428_3122	4.803e-56	205.0	COG5637@1|root,COG5637@2|Bacteria,1G2FS@1117|Cyanobacteria	1117|Cyanobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
ZZS3_k127_1003198_0	215803.DB30_4799	2.281e-109	364.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,43AHS@68525|delta/epsilon subdivisions,2WTYK@28221|Deltaproteobacteria,2YYVT@29|Myxococcales	28221|Deltaproteobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_1003198_5	1095769.CAHF01000010_gene1115	3.321e-44	173.0	COG5637@1|root,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,2WGS9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,Polyketide_cyc
ZZS3_k127_1003198_4	1115512.EH105704_01_03640	9.742e-49	183.0	COG0438@1|root,COG1232@1|root,COG2723@1|root,COG0438@2|Bacteria,COG1232@2|Bacteria,COG2723@2|Bacteria,1QU2N@1224|Proteobacteria,1RYA1@1236|Gammaproteobacteria,3XQHF@561|Escherichia	1236|Gammaproteobacteria	GHM	Glycosyl transferases group 1	VP1463	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,NAD_binding_8
ZZS3_k127_1003198_6	639030.JHVA01000001_gene1281	1.119e-12	74.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y6C4@57723|Acidobacteria,2JM8A@204432|Acidobacteriia	204432|Acidobacteriia	E	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1007810_33	861299.J421_3533	6.836e-57	200.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS3_k127_1007810_9	1379270.AUXF01000006_gene35	2.798e-157	504.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS3_k127_1007810_45	379066.GAU_1925	4.755e-37	149.0	COG0511@1|root,COG0511@2|Bacteria,1ZTR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
ZZS3_k127_1007810_28	635013.TherJR_1731	6.109e-65	228.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,261EB@186807|Peptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
ZZS3_k127_1007810_15	861299.J421_3535	6.109e-102	344.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
ZZS3_k127_1007810_41	69042.WH5701_06201	2.891e-47	173.0	COG0757@1|root,COG0757@2|Bacteria,1G5X4@1117|Cyanobacteria,1H0NE@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
ZZS3_k127_1007810_60	861299.J421_3537	1.485e-12	80.0	COG0457@1|root,COG0457@2|Bacteria,1ZTTU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
ZZS3_k127_1007810_14	861299.J421_3538	9.056e-114	390.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
ZZS3_k127_1007810_58	861299.J421_3539	1.588e-13	76.0	COG1826@1|root,COG1826@2|Bacteria,1ZU4N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
ZZS3_k127_1007810_55	1379270.AUXF01000006_gene28	1.948e-17	85.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
ZZS3_k127_1007810_16	861299.J421_3541	1.439e-100	339.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS3_k127_1007810_38	1379270.AUXF01000006_gene26	9.632e-50	202.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
ZZS3_k127_1007810_12	234267.Acid_5210	8.234e-138	455.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria	57723|Acidobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
ZZS3_k127_1007810_61	1379698.RBG1_1C00001G1236	2.158e-12	79.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
ZZS3_k127_1007810_13	861299.J421_3547	2.988e-133	467.0	COG1452@1|root,COG1452@2|Bacteria,1ZT14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1007810_39	379066.GAU_1939	1.457e-48	201.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
ZZS3_k127_1007810_65	1382359.JIAL01000001_gene2340	0.0001416	53.0	COG1729@1|root,COG1729@2|Bacteria,3Y3H6@57723|Acidobacteria,2JIES@204432|Acidobacteriia	204432|Acidobacteriia	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
ZZS3_k127_1007810_48	861299.J421_3550	1.075e-34	140.0	COG2885@1|root,COG2885@2|Bacteria,1ZTSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
ZZS3_k127_1007810_21	379066.GAU_1942	1.414e-91	318.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
ZZS3_k127_1007810_50	861299.J421_3552	1.059e-31	135.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
ZZS3_k127_1007810_46	861299.J421_3553	2.444e-36	141.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
ZZS3_k127_1007810_32	861299.J421_3554	1.074e-58	212.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
ZZS3_k127_1007810_18	379066.GAU_1946	2.643e-94	321.0	COG1087@1|root,COG1087@2|Bacteria,1ZSX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS3_k127_1007810_59	215803.DB30_4921	2.106e-13	82.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
ZZS3_k127_1007810_34	861299.J421_3557	3.812e-56	201.0	COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
ZZS3_k127_1007810_51	1286171.EAL2_c17650	1.989e-26	117.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,25XAS@186806|Eubacteriaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS3_k127_1007810_53	1392501.JIAC01000001_gene907	1.012e-19	99.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
ZZS3_k127_1007810_52	411467.BACCAP_03880	3.731e-23	112.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,269HY@186813|unclassified Clostridiales	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
ZZS3_k127_1007810_2	861299.J421_3561	1.404e-317	991.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
ZZS3_k127_1007810_43	867845.KI911784_gene3514	2.342e-44	168.0	COG2947@1|root,COG2947@2|Bacteria,2G93S@200795|Chloroflexi,375T3@32061|Chloroflexia	32061|Chloroflexia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
ZZS3_k127_1007810_62	1442599.JAAN01000046_gene2731	5.978e-09	63.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1007810_3	861299.J421_3563	6.386e-292	917.0	COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
ZZS3_k127_1007810_40	1125863.JAFN01000001_gene1051	2.062e-48	182.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
ZZS3_k127_1007810_1	1379270.AUXF01000003_gene3895	0.0	1229.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
ZZS3_k127_1007810_42	309801.trd_0651	6.478e-46	175.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,27Y96@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS3_k127_1007810_44	861299.J421_3568	3.602e-39	156.0	COG4105@1|root,COG4105@2|Bacteria,1ZTMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
ZZS3_k127_1007810_64	649638.Trad_0097	7.033e-05	54.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1WIRC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	COGs COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_8
ZZS3_k127_1007810_23	517418.Ctha_2482	1.838e-89	310.0	COG0451@1|root,COG0451@2|Bacteria,1FDWT@1090|Chlorobi	1090|Chlorobi	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
ZZS3_k127_1007810_6	861299.J421_0144	3.375e-178	568.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS3_k127_1007810_7	379066.GAU_0583	6.66e-176	564.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ZZS3_k127_1007810_10	861299.J421_3570	4.457e-151	486.0	COG0399@1|root,COG0399@2|Bacteria,1ZT81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ZZS3_k127_1007810_25	515635.Dtur_0577	4.412e-80	271.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
ZZS3_k127_1007810_27	1403313.AXBR01000021_gene3169	9.092e-66	237.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,1ZC3F@1386|Bacillus	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
ZZS3_k127_1007810_0	861299.J421_3571	0.0	1566.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
ZZS3_k127_1007810_29	861299.J421_3572	1.841e-60	221.0	COG0451@1|root,COG0451@2|Bacteria,1ZT9D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
ZZS3_k127_1007810_8	379066.GAU_1970	1.11e-160	511.0	COG1089@1|root,COG1089@2|Bacteria,1ZSR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
ZZS3_k127_1007810_54	796940.HMPREF9628_00853	3.63e-19	90.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
ZZS3_k127_1007810_47	861299.J421_3575	1.315e-35	150.0	COG0203@1|root,COG0203@2|Bacteria,1ZTPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
ZZS3_k127_1007810_11	1379270.AUXF01000003_gene3883	1.101e-138	450.0	COG0202@1|root,COG0202@2|Bacteria,1ZTEV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
ZZS3_k127_1007810_24	861299.J421_3577	4.606e-87	291.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
ZZS3_k127_1007810_30	861299.J421_3578	5.509e-60	209.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
ZZS3_k127_1007810_31	861299.J421_3579	5.899e-60	210.0	COG0099@1|root,COG0099@2|Bacteria,1ZTNX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
ZZS3_k127_1007810_57	379066.GAU_1977	4.399e-15	76.0	COG0257@1|root,COG0257@2|Bacteria,1ZVAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
ZZS3_k127_1007810_37	69042.WH5701_14856	7.038e-51	189.0	COG0284@1|root,COG0284@2|Bacteria,1GCQ3@1117|Cyanobacteria,1GZ1A@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
ZZS3_k127_1007810_20	861299.J421_3582	7.751e-93	314.0	COG0167@1|root,COG0167@2|Bacteria,1ZT86@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ZZS3_k127_1007810_26	379066.GAU_1980	1.534e-67	246.0	COG0860@1|root,COG0860@2|Bacteria,1ZSUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
ZZS3_k127_1007810_36	649639.Bcell_3511	3.754e-51	189.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus	91061|Bacilli	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
ZZS3_k127_1007810_5	1267535.KB906767_gene1049	2.608e-183	584.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
ZZS3_k127_1007810_49	44251.PDUR_03265	4.291e-33	132.0	COG1310@1|root,COG1310@2|Bacteria,1VKT4@1239|Firmicutes	1239|Firmicutes	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
ZZS3_k127_1007810_17	357808.RoseRS_0720	1.562e-95	322.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi,376HR@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_1007810_35	379066.GAU_1983	2.39e-54	196.0	COG1959@1|root,COG1959@2|Bacteria,1ZTRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ZZS3_k127_1007810_22	1095769.CAHF01000006_gene1870	1.459e-89	306.0	2DB86@1|root,2Z7QD@2|Bacteria,1MX4S@1224|Proteobacteria,2VKPI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
ZZS3_k127_1007810_19	1173027.Mic7113_2540	1.041e-93	314.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
ZZS3_k127_1007810_4	861299.J421_3587	8.995e-187	594.0	COG1027@1|root,COG1027@2|Bacteria,1ZSUY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
ZZS3_k127_1007810_56	42256.RradSPS_2277	1.707e-16	84.0	COG0662@1|root,COG0662@2|Bacteria,2GXJK@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_1023262_9	1121124.JNIX01000008_gene2318	2.09e-29	121.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2KG1J@204458|Caulobacterales	204458|Caulobacterales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
ZZS3_k127_1023262_7	1379270.AUXF01000003_gene3407	6.696e-76	259.0	COG5405@1|root,COG5405@2|Bacteria,1ZSVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
ZZS3_k127_1023262_6	1379270.AUXF01000003_gene3405	1.276e-95	321.0	COG4974@1|root,COG4974@2|Bacteria,1ZT3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS3_k127_1023262_1	1379270.AUXF01000003_gene3404	6.544e-174	563.0	COG1206@1|root,COG1206@2|Bacteria,1ZTB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	gid	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
ZZS3_k127_1023262_0	1501230.ET33_20160	2.596e-212	686.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,26R4N@186822|Paenibacillaceae	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
ZZS3_k127_1023262_10	379066.GAU_2511	7.285e-24	111.0	COG0703@1|root,COG0703@2|Bacteria,1ZTXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
ZZS3_k127_1023262_2	861299.J421_3974	5.196e-155	501.0	COG0082@1|root,COG0082@2|Bacteria,1ZT39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
ZZS3_k127_1023262_4	861299.J421_3976	4.836e-134	447.0	COG4796@1|root,COG4796@2|Bacteria,1ZSRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	AMIN domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
ZZS3_k127_1023262_14	1379270.AUXF01000003_gene3397	8.518e-13	79.0	2F6AC@1|root,33YU1@2|Bacteria,1ZTY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1023262_11	1379270.AUXF01000003_gene3396	2.306e-22	104.0	COG3167@1|root,COG3167@2|Bacteria,1ZTZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
ZZS3_k127_1023262_8	1379270.AUXF01000003_gene3395	1.811e-35	144.0	COG3166@1|root,COG3166@2|Bacteria,1ZTR8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
ZZS3_k127_1023262_3	379066.GAU_2518	2.543e-134	437.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
ZZS3_k127_1023262_15	1379270.AUXF01000002_gene1796	5.757e-09	63.0	28RPR@1|root,2ZE2C@2|Bacteria,1ZV82@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
ZZS3_k127_1023262_5	243231.GSU2041	1.24e-112	379.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U83@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_1023262_12	379066.GAU_0011	1.318e-20	97.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS3_k127_1023262_13	861299.J421_3986	3.878e-18	89.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilE	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl
ZZS3_k127_1184109_8	1303518.CCALI_00609	4.177e-111	361.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
ZZS3_k127_1184109_5	861299.J421_2089	5.747e-125	404.0	COG0396@1|root,COG0396@2|Bacteria,1ZSRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
ZZS3_k127_1184109_7	861299.J421_2088	3.74e-112	383.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
ZZS3_k127_1184109_2	1183438.GKIL_1933	5.588e-174	556.0	COG0520@1|root,COG0520@2|Bacteria,1G15D@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
ZZS3_k127_1184109_27	857087.Metme_1231	6.897e-46	173.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XF3J@135618|Methylococcales	135618|Methylococcales	C	TIGRFAM SUF system FeS	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
ZZS3_k127_1184109_26	1121346.KB899820_gene2763	6.241e-48	175.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,26WPV@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0403 family	yphP	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
ZZS3_k127_1184109_1	519989.ECTPHS_08773	3.17e-185	597.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales	135613|Chromatiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
ZZS3_k127_1184109_9	861299.J421_1165	4.669e-100	332.0	COG1192@1|root,COG1192@2|Bacteria,1ZTH2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
ZZS3_k127_1184109_19	861299.J421_1167	3.743e-75	262.0	COG1475@1|root,COG1475@2|Bacteria,1ZSKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
ZZS3_k127_1184109_32	1089553.Tph_c00390	3.818e-23	109.0	COG0739@1|root,COG5185@1|root,COG0739@2|Bacteria,COG5185@2|Bacteria,1V3ZU@1239|Firmicutes,24JM4@186801|Clostridia,42FFZ@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS3_k127_1184109_36	1089553.Tph_c00400	1.68e-10	67.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,42GQS@68295|Thermoanaerobacterales	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ZZS3_k127_1184109_16	861299.J421_1168	1.361e-84	291.0	COG1744@1|root,COG1744@2|Bacteria,1ZSMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
ZZS3_k127_1184109_21	1396141.BATP01000039_gene1303	1.185e-64	231.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
ZZS3_k127_1184109_6	861299.J421_1175	1.089e-120	405.0	COG3845@1|root,COG3845@2|Bacteria,1ZT2U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
ZZS3_k127_1184109_12	861299.J421_1178	9.689e-92	314.0	COG4603@1|root,COG4603@2|Bacteria,1ZTGR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ZZS3_k127_1184109_11	861299.J421_1179	3.569e-94	317.0	COG1079@1|root,COG1079@2|Bacteria,1ZSUD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ZZS3_k127_1184109_17	861299.J421_0084	1.412e-78	271.0	COG0204@1|root,COG0204@2|Bacteria,1ZSY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ZZS3_k127_1184109_13	861299.J421_1652	8.316e-87	301.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS3_k127_1184109_40	1219049.SP5_024_00050	9.713e-05	50.0	COG4253@1|root,COG4253@2|Bacteria,1RFXU@1224|Proteobacteria,2VDXQ@28211|Alphaproteobacteria,2K6CH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1184109_34	269799.Gmet_3328	3.935e-21	104.0	COG0346@1|root,COG0346@2|Bacteria,1NPMU@1224|Proteobacteria,42TZ4@68525|delta/epsilon subdivisions,2WQKA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_1184109_29	861299.J421_0552	4.691e-36	146.0	2DMJE@1|root,32RYR@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
ZZS3_k127_1184109_35	1144275.COCOR_01500	6.197e-17	85.0	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,42XZ1@68525|delta/epsilon subdivisions,2WTGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
ZZS3_k127_1184109_33	530564.Psta_0758	1.326e-22	106.0	COG2318@1|root,COG2318@2|Bacteria,2J1JI@203682|Planctomycetes	203682|Planctomycetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
ZZS3_k127_1184109_18	926562.Oweho_1921	3.108e-78	276.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia,2PA63@246874|Cryomorphaceae	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
ZZS3_k127_1184109_4	404589.Anae109_1625	1.029e-150	492.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ZZS3_k127_1184109_31	1379270.AUXF01000001_gene2453	3.556e-25	107.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1184109_14	1382306.JNIM01000001_gene1852	2.315e-85	289.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS3_k127_1184109_3	251221.35211608	2.34e-153	495.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
ZZS3_k127_1184109_30	290397.Adeh_3495	9.567e-35	136.0	COG1937@1|root,COG1937@2|Bacteria,1NIAR@1224|Proteobacteria,42XQ4@68525|delta/epsilon subdivisions,2X31E@28221|Deltaproteobacteria,2Z282@29|Myxococcales	28221|Deltaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
ZZS3_k127_1184109_0	290397.Adeh_3496	5.155e-269	848.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YX0C@29|Myxococcales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	copF	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
ZZS3_k127_1184109_37	1379270.AUXF01000001_gene2429	1.956e-10	64.0	COG2608@1|root,COG2608@2|Bacteria,1ZU70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
ZZS3_k127_1184109_39	1532558.JL39_25615	2.898e-05	57.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
ZZS3_k127_1184109_20	1379698.RBG1_1C00001G0109	1.119e-74	260.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
ZZS3_k127_1184109_15	880073.Calab_1818	3.996e-85	294.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
ZZS3_k127_1184109_28	880073.Calab_1819	2.292e-45	183.0	COG3170@1|root,COG3170@2|Bacteria,2NPXD@2323|unclassified Bacteria	2|Bacteria	NU	Tfp pilus assembly protein FimV	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	DUF4157,Pkinase
ZZS3_k127_1184109_22	926569.ANT_11780	3.384e-58	224.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ZZS3_k127_1184109_24	300852.55772144	3.617e-50	187.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_1184109_23	861299.J421_6034	1.596e-53	217.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,Guanylate_cyc,Trans_reg_C
ZZS3_k127_1184109_10	861299.J421_1230	1.193e-99	366.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1230|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
ZZS3_k127_1184109_25	401053.AciPR4_3726	7.104e-50	180.0	COG0596@1|root,COG0596@2|Bacteria,3Y610@57723|Acidobacteria,2JKYJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS3_k127_1236599_1	1047013.AQSP01000108_gene2058	2.018e-220	707.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
ZZS3_k127_1236599_6	861299.J421_0305	2.727e-55	204.0	COG1413@1|root,COG1413@2|Bacteria,1ZTU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS3_k127_1236599_2	861299.J421_0306	2.013e-94	331.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS3_k127_1236599_5	861299.J421_0308	1.122e-70	244.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_1236599_0	861299.J421_2396	0.0	1188.0	COG0188@1|root,COG0188@2|Bacteria,1ZTFF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
ZZS3_k127_1236599_3	47763.JNZA01000018_gene1564	5.258e-76	266.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_1236599_4	379066.GAU_0485	6.101e-73	255.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
ZZS3_k127_1272291_2	870187.Thini_4118	2.869e-35	146.0	COG3307@1|root,COG3307@2|Bacteria,1NGAP@1224|Proteobacteria,1SHNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS3_k127_1272291_1	1487953.JMKF01000021_gene2203	7.973e-36	146.0	COG1215@1|root,COG1215@2|Bacteria,1GPZX@1117|Cyanobacteria,1HCD3@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_1272291_0	1287116.X734_00330	2.853e-38	157.0	2EX7T@1|root,33QIK@2|Bacteria,1NI5F@1224|Proteobacteria,2UKAJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
ZZS3_k127_1272291_5	679926.Mpet_0041	2.656e-11	76.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,2NA3X@224756|Methanomicrobia	224756|Methanomicrobia	M	glycosyl transferase, family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS3_k127_1272291_3	379066.GAU_0585	2.09e-24	103.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS3_k127_1272295_37	1123256.KB907957_gene27	4.843e-121	400.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1X38S@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18298	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_1272295_1	402626.Rpic_4224	0.0	1442.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K386@119060|Burkholderiaceae	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	bepE_1	-	-	ko:K18902	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_1272295_33	861299.J421_0678	7.561e-124	413.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	oprN	-	-	ko:K18300,ko:K18308	-	M00641,M00644	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17,2.A.6.2.32	-	-	OEP
ZZS3_k127_1272295_147	1123508.JH636440_gene2902	3.413e-17	86.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_1272295_81	1121920.AUAU01000006_gene301	3.99e-71	245.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_30	316067.Geob_1385	4.904e-134	439.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
ZZS3_k127_1272295_34	518766.Rmar_1990	1.054e-123	406.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
ZZS3_k127_1272295_166	1185876.BN8_05467	0.0008796	48.0	29Q3N@1|root,30B2B@2|Bacteria,4NPCV@976|Bacteroidetes,47Q0V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_117	1501230.ET33_23150	1.921e-39	152.0	COG2318@1|root,COG2318@2|Bacteria,1VJN6@1239|Firmicutes,4HQ9H@91061|Bacilli,26W9D@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
ZZS3_k127_1272295_120	204669.Acid345_3730	1.487e-35	139.0	COG2259@1|root,COG2259@2|Bacteria,3Y8GR@57723|Acidobacteria,2JNIC@204432|Acidobacteriia	204432|Acidobacteriia	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_0	1380391.JIAS01000011_gene4883	0.0	1566.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2JPDT@204441|Rhodospirillales	204441|Rhodospirillales	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
ZZS3_k127_1272295_100	452637.Oter_1107	4.68e-54	201.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
ZZS3_k127_1272295_144	1444712.BN1013_00765	3.822e-18	86.0	COG2155@1|root,COG2155@2|Bacteria,2JGIY@204428|Chlamydiae	204428|Chlamydiae	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
ZZS3_k127_1272295_106	530564.Psta_4322	8.709e-49	180.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
ZZS3_k127_1272295_68	502025.Hoch_3922	7.631e-83	285.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,42V9E@68525|delta/epsilon subdivisions,2WRIJ@28221|Deltaproteobacteria,2Z0W1@29|Myxococcales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ZZS3_k127_1272295_10	1089550.ATTH01000001_gene1477	3.505e-205	666.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
ZZS3_k127_1272295_67	1121930.AQXG01000001_gene1299	6.703e-83	295.0	COG3391@1|root,COG3391@2|Bacteria,4PJH2@976|Bacteroidetes,1IZRD@117747|Sphingobacteriia	976|Bacteroidetes	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS3_k127_1272295_18	1121930.AQXG01000001_gene1300	4.563e-173	569.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1IYME@117747|Sphingobacteriia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
ZZS3_k127_1272295_93	861299.J421_0470	2.025e-62	234.0	COG0515@1|root,COG0515@2|Bacteria,1ZURQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_1272295_83	861299.J421_1666	5.47e-68	253.0	COG0515@1|root,COG0515@2|Bacteria,1ZUM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_1272295_107	530564.Psta_0826	1.239e-48	179.0	COG3685@1|root,COG3685@2|Bacteria,2IZPC@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
ZZS3_k127_1272295_146	1246995.AFR_20070	2.492e-17	87.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4DEUJ@85008|Micromonosporales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
ZZS3_k127_1272295_79	443143.GM18_0267	7.85e-73	253.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS3_k127_1272295_43	861299.J421_5988	1.751e-103	343.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
ZZS3_k127_1272295_2	861299.J421_5987	1.585e-315	988.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS3_k127_1272295_78	1297865.APJD01000015_gene3469	3.273e-74	256.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
ZZS3_k127_1272295_95	742818.HMPREF9451_00378	1.66e-59	235.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CUMT@84998|Coriobacteriia	84998|Coriobacteriia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS3_k127_1272295_143	1033739.CAEU01000003_gene1382	1.826e-18	93.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HF1C@91061|Bacilli,26F1V@186818|Planococcaceae	91061|Bacilli	M	NlpC/P60 family	iap	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3,SLH
ZZS3_k127_1272295_85	861299.J421_0395	8.235e-68	239.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Glutaredoxin
ZZS3_k127_1272295_31	861299.J421_0396	1.32e-132	433.0	COG1028@1|root,COG1028@2|Bacteria,1ZV1D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_1272295_165	68219.JNXI01000003_gene4859	0.0005437	49.0	2BUTG@1|root,32Q51@2|Bacteria,2ISEW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_156	861299.J421_1913	7.606e-12	72.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ZZS3_k127_1272295_158	1121918.ARWE01000001_gene2180	1.734e-11	74.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
ZZS3_k127_1272295_137	1158050.KB895472_gene2785	1.307e-23	106.0	2A4IR@1|root,30T5A@2|Bacteria,2H7PW@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1097
ZZS3_k127_1272295_11	316274.Haur_2968	7.043e-201	642.0	COG0699@1|root,COG0699@2|Bacteria,2G5JQ@200795|Chloroflexi,3753K@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Dynamin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
ZZS3_k127_1272295_124	861299.J421_1911	2.426e-31	130.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS3_k127_1272295_77	404589.Anae109_2572	5.549e-75	258.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS3_k127_1272295_59	379066.GAU_0710	6.655e-89	306.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_1272295_36	234267.Acid_1476	4.4e-121	400.0	COG0013@1|root,COG0013@2|Bacteria,3Y4AR@57723|Acidobacteria	57723|Acidobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ZZS3_k127_1272295_82	383372.Rcas_3054	6.979e-69	236.0	COG0229@1|root,COG0229@2|Bacteria,2G78V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
ZZS3_k127_1272295_51	1300345.LF41_1458	6.208e-100	342.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HTH_20,Peptidase_M29
ZZS3_k127_1272295_160	1396418.BATQ01000008_gene1500	1.293e-07	63.0	COG4307@1|root,COG4307@2|Bacteria,46U5T@74201|Verrucomicrobia,2IVFH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
ZZS3_k127_1272295_88	330214.NIDE0474	2.58e-65	236.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS3_k127_1272295_148	414996.IL38_08530	7.182e-17	94.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,407QZ@622450|Actinopolysporales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS3_k127_1272295_61	317013.NY99_20660	1.59e-87	305.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1S1J7@1236|Gammaproteobacteria,1X5N3@135614|Xanthomonadales	135614|Xanthomonadales	I	Cardiolipin synthetase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_1272295_163	1336235.JAEG01000001_gene2398	0.0001692	53.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,4BAW8@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
ZZS3_k127_1272295_87	861299.J421_3685	7.171e-66	233.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
ZZS3_k127_1272295_133	1283300.ATXB01000002_gene2657	1.733e-26	117.0	COG1266@1|root,COG1266@2|Bacteria,1RI59@1224|Proteobacteria,1S8JI@1236|Gammaproteobacteria,1XF1F@135618|Methylococcales	135618|Methylococcales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS3_k127_1272295_122	1379270.AUXF01000003_gene3743	7.121e-34	137.0	COG0778@1|root,COG0778@2|Bacteria,1ZTKQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
ZZS3_k127_1272295_84	163908.KB235895_gene5097	6.334e-68	238.0	COG1801@1|root,COG1801@2|Bacteria,1G2CT@1117|Cyanobacteria,1HMVF@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS3_k127_1272295_92	1121939.L861_10155	5.116e-63	224.0	COG3963@1|root,COG3963@2|Bacteria,1RATY@1224|Proteobacteria,1S1YM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	methyltransferase	ksgA1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
ZZS3_k127_1272295_112	379066.GAU_0068	1.258e-44	169.0	2E7CK@1|root,331VT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_40	861299.J421_2063	1.921e-112	372.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
ZZS3_k127_1272295_154	861299.J421_1004	2.873e-13	79.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_1272295_4	861299.J421_2344	7.491e-238	755.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
ZZS3_k127_1272295_134	468059.AUHA01000002_gene175	1.111e-25	117.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
ZZS3_k127_1272295_28	1125863.JAFN01000001_gene886	2.298e-135	448.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_1272295_75	861299.J421_1049	1.087e-75	261.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
ZZS3_k127_1272295_161	1121930.AQXG01000002_gene2352	1.628e-07	60.0	COG2373@1|root,COG2755@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG4412@1|root,COG4932@1|root,COG2373@2|Bacteria,COG2755@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	pelX	-	-	ko:K07004,ko:K09955,ko:K16915,ko:K20276	ko02010,ko02024,map02010,map02024	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	Beta_helix,Laminin_G_3
ZZS3_k127_1272295_139	861299.J421_0387	1.457e-22	109.0	COG1196@1|root,COG1196@2|Bacteria,1ZU2U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_8	1089550.ATTH01000001_gene363	2.34e-214	698.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1FJXK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
ZZS3_k127_1272295_7	1210884.HG799464_gene10885	7.552e-229	719.0	COG1233@1|root,COG1233@2|Bacteria,2IX17@203682|Planctomycetes	203682|Planctomycetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
ZZS3_k127_1272295_135	99598.Cal7507_0676	1.518e-24	105.0	COG3162@1|root,COG3162@2|Bacteria,1GB35@1117|Cyanobacteria,1HSX2@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
ZZS3_k127_1272295_5	1379270.AUXF01000005_gene464	7.363e-234	733.0	COG4147@1|root,COG4147@2|Bacteria,1ZUA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
ZZS3_k127_1272295_32	324602.Caur_2349	2.563e-128	422.0	COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi,377BT@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
ZZS3_k127_1272295_149	379066.GAU_0190	9.679e-17	86.0	2BF26@1|root,328U5@2|Bacteria,1ZV0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF3568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3568
ZZS3_k127_1272295_15	861299.J421_2329	1.076e-180	583.0	COG0179@1|root,COG0179@2|Bacteria,1ZT8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Fumarylacetoacetase N-terminal	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
ZZS3_k127_1272295_74	1128421.JAGA01000001_gene2398	8.48e-76	264.0	COG0124@1|root,COG0124@2|Bacteria	2|Bacteria	J	histidine-tRNA ligase activity	hisZ	-	6.1.1.21	ko:K01892,ko:K02502	ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230	M00026,M00359,M00360	R01071,R03655	RC00055,RC00523,RC02819,RC03200	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
ZZS3_k127_1272295_14	1192034.CAP_8820	6.52e-187	598.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_1272295_17	861299.J421_6055	1.177e-176	569.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	2.1.1.242,2.1.1.303,2.1.1.319	ko:K11434,ko:K15984,ko:K20421	ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922	M00830	R10963,R11216,R11217,R11219	RC00003,RC00392,RC02120,RC03388,RC03390	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	-	-	-	DOT1,Methyltransf_21,Methyltransf_25
ZZS3_k127_1272295_47	861299.J421_0143	4.305e-101	348.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS3_k127_1272295_60	118168.MC7420_864	1.546e-88	301.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Ribonuclease BN-like family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ZZS3_k127_1272295_91	398767.Glov_0084	9e-64	226.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
ZZS3_k127_1272295_23	1120971.AUCA01000001_gene1727	3.47e-154	496.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,278WZ@186823|Alicyclobacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_1272295_126	1146883.BLASA_1918	1.861e-29	123.0	COG2905@1|root,COG2905@2|Bacteria,2I5MP@201174|Actinobacteria,4EXD4@85013|Frankiales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS3_k127_1272295_141	671143.DAMO_1987	1.114e-20	98.0	COG2259@1|root,COG2259@2|Bacteria,2NQ4C@2323|unclassified Bacteria	2|Bacteria	S	DoxX	ndh	-	1.6.99.3,1.8.5.2	ko:K03885,ko:K16937	ko00190,ko00920,ko01120,map00190,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxD,DoxX,Pyr_redox_2
ZZS3_k127_1272295_3	98439.AJLL01000010_gene1388	8.587e-267	840.0	COG1770@1|root,COG1770@2|Bacteria,1G1RH@1117|Cyanobacteria,1JHGU@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
ZZS3_k127_1272295_125	1379270.AUXF01000002_gene1400	7.067e-31	132.0	29X7E@1|root,30IWN@2|Bacteria,1ZV4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
ZZS3_k127_1272295_94	1123368.AUIS01000003_gene1752	4.812e-62	221.0	28H8Z@1|root,30SVT@2|Bacteria,1PCCT@1224|Proteobacteria,1SWRM@1236|Gammaproteobacteria,2NDY3@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
ZZS3_k127_1272295_22	404589.Anae109_1755	2.225e-158	515.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_1272295_73	292459.STH1979	2.25e-76	263.0	COG1573@1|root,COG1573@2|Bacteria,1V2PR@1239|Firmicutes,24JK1@186801|Clostridia	186801|Clostridia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS3_k127_1272295_12	861299.J421_2513	3.004e-195	617.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
ZZS3_k127_1272295_56	861299.J421_2514	1.089e-90	316.0	COG0477@1|root,COG2814@2|Bacteria,1ZSUR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
ZZS3_k127_1272295_129	485913.Krac_11720	2.284e-27	124.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
ZZS3_k127_1272295_9	861299.J421_2518	4.462e-208	657.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
ZZS3_k127_1272295_116	1379270.AUXF01000004_gene3295	6.397e-40	162.0	COG0354@1|root,COG0354@2|Bacteria,1ZTMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
ZZS3_k127_1272295_119	330214.NIDE1522	6.125e-37	147.0	COG0637@1|root,COG0637@2|Bacteria,3J15X@40117|Nitrospirae	40117|Nitrospirae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS3_k127_1272295_39	861299.J421_2523	1.091e-113	381.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
ZZS3_k127_1272295_114	269084.syc2373_d	6.35e-41	173.0	COG0277@1|root,COG0277@2|Bacteria,1G176@1117|Cyanobacteria,1GYXW@1129|Synechococcus	1117|Cyanobacteria	C	Glycolate oxidase subunit GlcE	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_1272295_16	379066.GAU_0600	2.194e-180	578.0	COG0277@1|root,COG0277@2|Bacteria,1ZT11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_1272295_110	861299.J421_2526	8.858e-46	174.0	COG2802@1|root,COG2802@2|Bacteria,1ZUZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
ZZS3_k127_1272295_29	379066.GAU_0602	2.788e-134	435.0	COG0568@1|root,COG0568@2|Bacteria,1ZSNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_1272295_57	861299.J421_2532	4.903e-90	308.0	COG0337@1|root,COG0337@2|Bacteria,1ZSS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
ZZS3_k127_1272295_86	379066.GAU_0604	2.738e-66	232.0	COG2096@1|root,COG2096@2|Bacteria,1ZT4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
ZZS3_k127_1272295_41	379066.GAU_0605	1.029e-111	370.0	COG0492@1|root,COG0492@2|Bacteria,1ZSM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
ZZS3_k127_1272295_162	1121946.AUAX01000014_gene1212	6.317e-05	55.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D9MF@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
ZZS3_k127_1272295_76	204669.Acid345_4495	3.051e-75	272.0	COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria,2JIBN@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS3_k127_1272295_26	861299.J421_2540	5.816e-139	448.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_1272295_20	861299.J421_2541	6.992e-163	529.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_1272295_35	1379270.AUXF01000004_gene3276	1.424e-121	416.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
ZZS3_k127_1272295_69	1379270.AUXF01000003_gene3794	1.419e-82	313.0	COG2911@1|root,COG2911@2|Bacteria,1ZUEH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
ZZS3_k127_1272295_115	861299.J421_2546	6.835e-41	167.0	COG1597@1|root,COG1597@2|Bacteria,1ZU66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
ZZS3_k127_1272295_46	1265505.ATUG01000001_gene3441	2.838e-101	346.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,2MMRB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_1272295_121	379066.GAU_0611	6.852e-35	144.0	COG0791@1|root,COG0791@2|Bacteria,1ZTVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
ZZS3_k127_1272295_102	861299.J421_2552	9.305e-54	197.0	COG0546@1|root,COG0546@2|Bacteria,1ZTK9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
ZZS3_k127_1272295_155	479434.Sthe_1192	1.632e-12	77.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi,27YDS@189775|Thermomicrobia	189775|Thermomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
ZZS3_k127_1272295_52	1123368.AUIS01000004_gene281	9.194e-97	342.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Iron Permease	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
ZZS3_k127_1272295_101	1121004.ATVC01000074_gene1230	8.685e-54	193.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,2VR2C@28216|Betaproteobacteria,2KR48@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	menG	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
ZZS3_k127_1272295_89	379066.GAU_0618	4.111e-64	231.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
ZZS3_k127_1272295_45	379066.GAU_0619	1.085e-101	345.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
ZZS3_k127_1272295_108	861299.J421_2562	1.224e-47	176.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS3_k127_1272295_80	379066.GAU_0621	1.978e-71	252.0	COG0036@1|root,COG0036@2|Bacteria,1ZSP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ZZS3_k127_1272295_159	1348663.KCH_21840	2.666e-10	69.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2M1AC@2063|Kitasatospora	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ZZS3_k127_1272295_53	861299.J421_2565	1.63e-95	329.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
ZZS3_k127_1272295_54	243231.GSU0588	2.285e-94	317.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43TNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
ZZS3_k127_1272295_153	158500.BV97_02176	3.811e-14	78.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2UG5I@28211|Alphaproteobacteria,2K74Y@204457|Sphingomonadales	204457|Sphingomonadales	H	Bifunctional sulfur carrier protein thiazole synthase	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ZZS3_k127_1272295_132	309801.trd_0401	9.695e-27	119.0	COG0352@1|root,COG0352@2|Bacteria,2G9BW@200795|Chloroflexi,27YDG@189775|Thermomicrobia	189775|Thermomicrobia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
ZZS3_k127_1272295_58	861299.J421_2566	3.533e-89	304.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
ZZS3_k127_1272295_113	379066.GAU_0625	1.026e-43	170.0	COG0242@1|root,COG0242@2|Bacteria,1ZTPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ZZS3_k127_1272295_157	384765.SIAM614_13793	1.693e-11	70.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Preprotein translocase subunit (YajC)	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
ZZS3_k127_1272295_27	379066.GAU_0627	6.668e-138	448.0	COG0343@1|root,COG0343@2|Bacteria,1ZSRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
ZZS3_k127_1272295_128	1463887.KL589954_gene7191	3.076e-29	123.0	COG2318@1|root,COG2318@2|Bacteria,2GXK3@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_1272295_44	861299.J421_2570	2.786e-102	345.0	COG0809@1|root,COG0809@2|Bacteria,1ZSV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
ZZS3_k127_1272295_24	379066.GAU_0629	8.409e-147	472.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
ZZS3_k127_1272295_118	861299.J421_2579	7.633e-39	159.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
ZZS3_k127_1272295_104	861299.J421_2580	1.378e-51	188.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
ZZS3_k127_1272295_55	1379270.AUXF01000004_gene3247	1.25e-92	310.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
ZZS3_k127_1272295_105	1379270.AUXF01000004_gene3246	3.043e-50	191.0	COG0305@1|root,COG0305@2|Bacteria,1ZUU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DnaB-like helicase C terminal domain	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_C
ZZS3_k127_1272295_99	880073.Calab_0968	4.015e-55	207.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS3_k127_1272295_13	379066.GAU_0638	3.418e-194	619.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
ZZS3_k127_1272295_25	1379270.AUXF01000004_gene3243	3.788e-140	466.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
ZZS3_k127_1272295_97	203122.Sde_3741	6.812e-59	214.0	COG0463@1|root,COG0463@2|Bacteria,1QX0V@1224|Proteobacteria,1T32V@1236|Gammaproteobacteria,4647P@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
ZZS3_k127_1272295_131	526218.Sterm_3098	3.524e-27	126.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_1272295_98	313606.M23134_08164	3.722e-57	211.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,47MB5@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
ZZS3_k127_1272295_145	595536.ADVE02000001_gene438	6.069e-18	95.0	COG4641@1|root,COG4641@2|Bacteria,1RBIX@1224|Proteobacteria,2U644@28211|Alphaproteobacteria,36Z8M@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ZZS3_k127_1272295_103	219305.MCAG_01273	1.483e-52	201.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DB93@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferases group 1	pimB	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_1272295_62	861299.J421_4225	6.901e-87	301.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
ZZS3_k127_1272295_49	861299.J421_2587	6.057e-100	334.0	COG1173@1|root,COG1173@2|Bacteria,1ZT0U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
ZZS3_k127_1272295_48	379066.GAU_0642	9.854e-101	340.0	COG0520@1|root,COG0520@2|Bacteria,1ZTDV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS3_k127_1272295_19	1121385.AQXW01000004_gene2404	1.161e-169	547.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,1ZVCW@145357|Dermacoccaceae	201174|Actinobacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
ZZS3_k127_1272295_38	1396418.BATQ01000046_gene6113	5.601e-117	400.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
ZZS3_k127_1272295_6	861299.J421_2591	1.131e-231	739.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
ZZS3_k127_1272295_72	861299.J421_2593	1.501e-77	276.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_1272295_130	1160707.AJIK01000006_gene1006	2.846e-27	117.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,26EXC@186818|Planococcaceae	91061|Bacilli	K	Regulates arginine biosynthesis genes	argR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
ZZS3_k127_1272295_63	861299.J421_2594	1.994e-86	291.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
ZZS3_k127_1272295_142	861299.J421_2595	5.138e-20	101.0	2F73W@1|root,33ZJG@2|Bacteria,1ZTT7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_71	379066.GAU_0648	2.283e-80	291.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Peptidase_S74
ZZS3_k127_1272295_21	379066.GAU_0649	1.08e-160	518.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_1272295_66	1379270.AUXF01000004_gene3229	2.506e-83	290.0	COG5000@1|root,COG5000@2|Bacteria,1ZTBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS3_k127_1272295_96	102129.Lepto7375DRAFT_5494	3.89e-59	214.0	COG0500@1|root,COG2226@2|Bacteria,1G3CH@1117|Cyanobacteria,1HAB6@1150|Oscillatoriales	1117|Cyanobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_1272295_64	247490.KSU1_C0431	7.986e-84	298.0	COG2244@1|root,COG2244@2|Bacteria,2J1D3@203682|Planctomycetes	203682|Planctomycetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
ZZS3_k127_1272295_127	338966.Ppro_2460	2.615e-29	131.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_1272295_138	525904.Tter_1175	2.801e-23	112.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	yxbB	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
ZZS3_k127_1272295_65	1449350.OCH239_17360	1.358e-83	289.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
ZZS3_k127_1272295_109	1047013.AQSP01000139_gene2419	2.856e-47	185.0	COG0500@1|root,COG2226@2|Bacteria,2NQZU@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
ZZS3_k127_1272295_111	1088721.NSU_1093	5.873e-45	178.0	COG2244@1|root,COG2244@2|Bacteria,1NX2R@1224|Proteobacteria,2USND@28211|Alphaproteobacteria,2KAHK@204457|Sphingomonadales	204457|Sphingomonadales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1272295_42	489825.LYNGBM3L_62230	2.078e-106	361.0	COG0438@1|root,COG0438@2|Bacteria,1G0AQ@1117|Cyanobacteria,1HA76@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_1272295_50	489825.LYNGBM3L_22490	6.138e-100	345.0	COG0578@1|root,COG0578@2|Bacteria,1G1T3@1117|Cyanobacteria,1H86N@1150|Oscillatoriales	1117|Cyanobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
ZZS3_k127_1272295_90	472759.Nhal_3328	5.659e-64	232.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXFS@135613|Chromatiales	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_1272295_70	766499.C357_22955	7.696e-82	284.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2TTR9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_1272295_136	379066.GAU_0585	3.942e-24	102.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS3_k127_1406054_12	861299.J421_3777	1.005e-38	148.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS3_k127_1406054_17	591159.ACEZ01000137_gene2253	1.22e-05	48.0	COG4329@1|root,COG4329@2|Bacteria,2IIU1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2243
ZZS3_k127_1406054_16	1121957.ATVL01000008_gene4589	2.025e-12	72.0	COG4329@1|root,COG4329@2|Bacteria,4NRQA@976|Bacteroidetes,47Q9M@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2243
ZZS3_k127_1406054_14	1236976.JCM16418_1927	1.164e-34	142.0	COG3861@1|root,COG3861@2|Bacteria,1V5RZ@1239|Firmicutes,4HHAU@91061|Bacilli,26SHD@186822|Paenibacillaceae	91061|Bacilli	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	YflT
ZZS3_k127_1406054_13	211165.AJLN01000098_gene5204	1.724e-38	160.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JKN9@1189|Stigonemataceae	1117|Cyanobacteria	T	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_1406054_2	518766.Rmar_1775	9.38e-217	691.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase, family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
ZZS3_k127_1406054_10	861299.J421_0482	1.558e-61	219.0	COG0546@1|root,COG0590@1|root,COG0546@2|Bacteria,COG0590@2|Bacteria,1ZU5R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FJ	Haloacid dehalogenase-like hydrolase	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_1406054_5	861299.J421_3849	7.6e-129	430.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_1406054_1	861299.J421_3848	1.087e-321	993.0	COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ZZS3_k127_1406054_15	96561.Dole_2317	6.882e-14	76.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1406054_4	251229.Chro_1130	7.501e-134	437.0	COG0673@1|root,COG0673@2|Bacteria,1G18V@1117|Cyanobacteria,3VNCD@52604|Pleurocapsales	1117|Cyanobacteria	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	1.1.1.335,1.1.99.28	ko:K00118,ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS3_k127_1406054_7	243233.MCA2616	2.282e-83	283.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1S510@1236|Gammaproteobacteria,1XEBJ@135618|Methylococcales	135618|Methylococcales	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS3_k127_1406054_3	1128421.JAGA01000003_gene3727	1.154e-151	495.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
ZZS3_k127_1406054_0	649638.Trad_0840	0.0	1114.0	COG1012@1|root,COG1012@2|Bacteria,1WIGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_1406054_11	1379270.AUXF01000003_gene3561	1.869e-60	229.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1ZTH0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FPT	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
ZZS3_k127_1406054_9	379066.GAU_2370	2.372e-69	244.0	COG0704@1|root,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
ZZS3_k127_1406054_6	562970.Btus_2532	7.756e-101	344.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,277YK@186823|Alicyclobacillaceae	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS3_k127_1406054_8	1121382.JQKG01000011_gene554	1.608e-70	241.0	COG1117@1|root,COG1117@2|Bacteria,1WI7W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ZZS3_k127_1416852_13	251221.35211731	6.756e-137	444.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
ZZS3_k127_1416852_14	118173.KB235914_gene2350	2.47e-131	432.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1H8TZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_1416852_2	861299.J421_1872	6.796e-283	877.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
ZZS3_k127_1416852_29	861299.J421_1881	3.141e-57	211.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,PD40
ZZS3_k127_1416852_30	861299.J421_1880	2.432e-51	189.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
ZZS3_k127_1416852_20	251229.Chro_3613	2.937e-85	293.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria	1117|Cyanobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
ZZS3_k127_1416852_4	1496688.ER33_11555	6.339e-252	794.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
ZZS3_k127_1416852_0	1242864.D187_003480	0.0	1324.0	COG1429@1|root,COG1429@2|Bacteria,1QX7D@1224|Proteobacteria,43C0E@68525|delta/epsilon subdivisions,2X7B3@28221|Deltaproteobacteria,2Z3EW@29|Myxococcales	28221|Deltaproteobacteria	H	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
ZZS3_k127_1416852_43	861299.J421_1850	7.39e-24	103.0	2CN2H@1|root,32SG5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_49	1267535.KB906767_gene1543	1.509e-09	59.0	2CN2H@1|root,32SG5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_26	1192034.CAP_5638	2.232e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2X3DW@28221|Deltaproteobacteria,2YUWD@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_1416852_9	1123508.JH636444_gene5539	8.14e-159	533.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_1416852_37	861299.J421_2968	2.717e-38	162.0	COG1947@1|root,COG1947@2|Bacteria,1ZTM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
ZZS3_k127_1416852_27	379066.GAU_1245	2.645e-59	219.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS3_k127_1416852_46	861299.J421_2970	1.399e-13	84.0	2CB0K@1|root,343GC@2|Bacteria,1ZU4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
ZZS3_k127_1416852_21	379066.GAU_1247	2.337e-83	282.0	COG0854@1|root,COG0854@2|Bacteria,1ZSPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
ZZS3_k127_1416852_47	861299.J421_2972	1.335e-11	71.0	28ZEQ@1|root,2ZM6A@2|Bacteria,1ZU2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_34	861299.J421_2973	3.23e-43	166.0	COG0346@1|root,COG0346@2|Bacteria,1ZTMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
ZZS3_k127_1416852_35	861299.J421_2974	7.675e-43	163.0	COG3118@1|root,COG3118@2|Bacteria,1ZTS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ZZS3_k127_1416852_25	1183438.GKIL_1263	3.599e-67	241.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
ZZS3_k127_1416852_19	861299.J421_2976	6.229e-92	306.0	COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
ZZS3_k127_1416852_18	861299.J421_2977	6.152e-103	372.0	COG1196@1|root,COG4942@1|root,COG1196@2|Bacteria,COG4942@2|Bacteria,1ZSU8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_38	861299.J421_2978	1.696e-34	151.0	COG1729@1|root,COG1729@2|Bacteria,1ZTBJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	-
ZZS3_k127_1416852_7	1379270.AUXF01000005_gene568	9.384e-164	526.0	2CD20@1|root,2Z7SQ@2|Bacteria,1ZTFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_3	861299.J421_2981	4.174e-277	876.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
ZZS3_k127_1416852_22	861299.J421_2983	2.416e-73	252.0	COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
ZZS3_k127_1416852_15	1379270.AUXF01000003_gene3730	4.355e-131	429.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_1416852_39	379066.GAU_0290	6.684e-29	123.0	2F3IF@1|root,33WC0@2|Bacteria,1ZTPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_23	483219.LILAB_08725	2.438e-68	249.0	COG2843@1|root,COG2843@2|Bacteria,1Q4SV@1224|Proteobacteria,42ZT3@68525|delta/epsilon subdivisions,2WV46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
ZZS3_k127_1416852_10	861299.J421_2986	1.425e-158	514.0	COG0008@1|root,COG0008@2|Bacteria,1ZSSX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ZZS3_k127_1416852_40	1449049.JONW01000011_gene2311	4.621e-28	120.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1416852_41	584708.Apau_0710	2.314e-27	116.0	COG3275@1|root,COG4191@1|root,COG3275@2|Bacteria,COG4191@2|Bacteria,3TBCP@508458|Synergistetes	508458|Synergistetes	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS3_k127_1416852_36	1121937.AUHJ01000008_gene1989	1.478e-40	166.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,46CMH@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	gt4G	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_1416852_48	561230.PC1_2925	4.457e-10	72.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,1RQ0R@1236|Gammaproteobacteria,1MRB8@122277|Pectobacterium	1236|Gammaproteobacteria	G	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnD	GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896	-	ko:K13014	ko00520,ko01503,map00520,map01503	M00721,M00761	R07662	RC00323,RC01575	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iB21_1397.B21_02141,iBWG_1329.BWG_2029,iEC042_1314.EC042_2499,iECBD_1354.ECBD_1403,iECB_1328.ECB_02182,iECDH10B_1368.ECDH10B_2416,iECDH1ME8569_1439.ECDH1ME8569_2192,iECD_1391.ECD_02182,iECO103_1326.ECO103_2722,iECO111_1330.ECO111_3006,iECO26_1355.ECO26_3246,iECUMN_1333.ECUMN_2597,iECW_1372.ECW_m2447,iEKO11_1354.EKO11_1508,iETEC_1333.ETEC_2390,iEcDH1_1363.EcDH1_1402,iEcHS_1320.EcHS_A2401,iEcolC_1368.EcolC_1393,iJO1366.b2256,iSFV_1184.SFV_2326,iSSON_1240.SSON_2317,iUMNK88_1353.UMNK88_2808,iWFL_1372.ECW_m2447,iY75_1357.Y75_RS11830	Polysacc_deac_1
ZZS3_k127_1416852_16	861450.HMPREF0080_01495	3.454e-128	421.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4H2UD@909932|Negativicutes	909932|Negativicutes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
ZZS3_k127_1416852_24	472759.Nhal_3310	2.272e-67	244.0	COG0451@1|root,COG0451@2|Bacteria,1PG2X@1224|Proteobacteria,1RWX5@1236|Gammaproteobacteria,1X0Z7@135613|Chromatiales	135613|Chromatiales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ZZS3_k127_1416852_32	1499967.BAYZ01000090_gene4954	4.868e-47	186.0	COG0500@1|root,COG2226@2|Bacteria,2NQZU@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
ZZS3_k127_1416852_12	1499967.BAYZ01000069_gene1838	2.729e-144	480.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ZZS3_k127_1416852_8	379066.GAU_1277	9.263e-163	541.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,1ZT9A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
ZZS3_k127_1416852_6	1379270.AUXF01000005_gene585	4.116e-176	565.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
ZZS3_k127_1416852_28	518766.Rmar_1872	4.779e-58	210.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1FITI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
ZZS3_k127_1416852_31	861299.J421_2991	2.819e-51	194.0	COG0241@1|root,COG0241@2|Bacteria,1ZTT8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
ZZS3_k127_1416852_17	1121033.AUCF01000005_gene5309	2.239e-122	407.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales	204441|Rhodospirillales	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
ZZS3_k127_1416852_33	379066.GAU_1282	3.606e-46	188.0	COG2372@1|root,COG2372@2|Bacteria,1ZTUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
ZZS3_k127_1416852_1	269799.Gmet_0956	6.184e-286	903.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
ZZS3_k127_1416852_5	234267.Acid_7295	2.067e-207	666.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
ZZS3_k127_1416852_11	1379698.RBG1_1C00001G1459	1.136e-153	495.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_1416852_51	467200.ACFA01000603_gene4992	0.0002217	52.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria	201174|Actinobacteria	S	BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
ZZS3_k127_1416852_42	861299.J421_3001	1.791e-24	118.0	COG1266@1|root,COG1266@2|Bacteria,1ZTXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS3_k127_1466346_44	1242864.D187_008484	4.438e-13	81.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42MEY@68525|delta/epsilon subdivisions,2WM0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
ZZS3_k127_1466346_19	309807.SRU_1436	1.779e-78	270.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,1FJI0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
ZZS3_k127_1466346_34	224324.aq_199	9.618e-37	154.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	yocB	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
ZZS3_k127_1466346_43	1157637.KB892091_gene5432	4.005e-15	82.0	COG2905@1|root,COG2905@2|Bacteria,2IJJ6@201174|Actinobacteria	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS3_k127_1466346_41	1123368.AUIS01000032_gene1389	1.737e-18	89.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
ZZS3_k127_1466346_4	1379270.AUXF01000003_gene3360	2.532e-174	576.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	2|Bacteria	P	E1-E2 ATPase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
ZZS3_k127_1466346_22	697282.Mettu_1426	6.678e-71	246.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,1XGZ4@135618|Methylococcales	135618|Methylococcales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_1466346_25	671143.DAMO_3124	3.659e-56	213.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,SpoIIE,sCache_3_2
ZZS3_k127_1466346_47	644966.Tmar_1832	5.263e-07	61.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_1466346_48	391593.RCCS2_08879	0.000164	53.0	COG0589@1|root,COG0589@2|Bacteria,1N7EK@1224|Proteobacteria,2UG87@28211|Alphaproteobacteria,2P59U@2433|Roseobacter	28211|Alphaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_1466346_45	1547437.LL06_19040	1.351e-09	63.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,43QQ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
ZZS3_k127_1466346_26	383372.Rcas_3776	7.543e-52	196.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_1466346_10	344747.PM8797T_16675	1.703e-114	386.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ZZS3_k127_1466346_16	118168.MC7420_1742	1.655e-84	291.0	COG3217@1|root,COG3217@2|Bacteria,1G41J@1117|Cyanobacteria,1HA5C@1150|Oscillatoriales	1117|Cyanobacteria	S	Fe-S protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
ZZS3_k127_1466346_30	861299.J421_1222	1.44e-40	153.0	COG1393@1|root,COG1393@2|Bacteria,1ZTUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
ZZS3_k127_1466346_3	1379270.AUXF01000002_gene1243	1.803e-190	616.0	COG0488@1|root,COG0488@2|Bacteria,1ZSV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
ZZS3_k127_1466346_24	1089551.KE386572_gene4417	2.724e-69	241.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,4BRZ8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
ZZS3_k127_1466346_29	1379270.AUXF01000001_gene2307	5.987e-41	159.0	COG1309@1|root,COG1309@2|Bacteria,1ZTWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_1466346_12	861299.J421_2015	1.433e-100	350.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS3_k127_1466346_14	215803.DB30_4552	9.758e-90	311.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42RBE@68525|delta/epsilon subdivisions,2WN7J@28221|Deltaproteobacteria,2YZ5D@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_1466346_0	1144275.COCOR_00464	0.0	1479.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
ZZS3_k127_1466346_18	2423.NA23_0202175	8.397e-82	290.0	COG1653@1|root,COG1653@2|Bacteria,2GC1I@200918|Thermotogae	200918|Thermotogae	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
ZZS3_k127_1466346_13	580331.Thit_0425	1.715e-92	313.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,42FWJ@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
ZZS3_k127_1466346_15	484019.THA_846	1.363e-84	301.0	COG0395@1|root,COG0395@2|Bacteria,2GCIV@200918|Thermotogae	200918|Thermotogae	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ZZS3_k127_1466346_11	1500890.JQNL01000001_gene1611	5.285e-109	362.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1X4C8@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
ZZS3_k127_1466346_2	861299.J421_6272	2.502e-231	741.0	28MSW@1|root,2ZB15@2|Bacteria,1ZUI9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1466346_5	1267535.KB906767_gene1523	5.812e-163	539.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	kojP	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
ZZS3_k127_1466346_8	880073.Calab_2972	3.945e-129	447.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_1466346_40	861299.J421_6270	5.472e-24	114.0	2DJDE@1|root,305RC@2|Bacteria,1ZV7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1466346_1	861299.J421_6271	4.813e-295	915.0	COG0591@1|root,COG0591@2|Bacteria,1ZU9T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
ZZS3_k127_1466346_20	379066.GAU_2138	4.744e-73	254.0	COG2859@1|root,COG2859@2|Bacteria,1ZUNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
ZZS3_k127_1466346_6	234267.Acid_7338	5.065e-136	460.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_1466346_7	1121930.AQXG01000011_gene1720	1.847e-132	449.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_1466346_38	1121448.DGI_1726	7.091e-26	116.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,42R9E@68525|delta/epsilon subdivisions,2WNRJ@28221|Deltaproteobacteria,2MAXH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_1466346_39	1403819.BATR01000191_gene6519	1.341e-25	112.0	COG5642@1|root,COG5642@2|Bacteria,46XIK@74201|Verrucomicrobia,2IW0M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
ZZS3_k127_1466346_35	290397.Adeh_1751	4.95e-36	142.0	COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,42V1X@68525|delta/epsilon subdivisions,2WRR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
ZZS3_k127_1466346_36	82654.Pse7367_2979	4.966e-31	129.0	COG2319@1|root,COG2319@2|Bacteria,1GKHN@1117|Cyanobacteria,1HFV2@1150|Oscillatoriales	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1466346_37	485913.Krac_4433	1.141e-28	121.0	COG0251@1|root,COG0251@2|Bacteria,2G9SU@200795|Chloroflexi	2|Bacteria	J	translation initiation inhibitor yjgF family	MA20_36215	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS3_k127_1466346_17	204669.Acid345_0678	5.737e-82	289.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	yagE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
ZZS3_k127_1466346_27	1242864.D187_002182	3.07e-50	185.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
ZZS3_k127_1466346_33	1038860.AXAP01000014_gene946	1.936e-37	145.0	COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,3JTKI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS3_k127_1466346_28	1041146.ATZB01000027_gene5785	3.004e-41	157.0	COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,4B7D5@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
ZZS3_k127_1466346_9	420324.KI912068_gene6491	2.347e-116	398.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,1JRF3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1466346_46	861299.J421_1004	1.352e-08	66.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_1466346_23	190650.CC_3179	3.183e-70	249.0	COG2159@1|root,COG2159@2|Bacteria,1PTY1@1224|Proteobacteria,2V5RF@28211|Alphaproteobacteria,2KHVI@204458|Caulobacterales	204458|Caulobacterales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
ZZS3_k127_1466346_21	935863.AWZR01000007_gene259	7.516e-72	250.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
ZZS3_k127_1466346_31	926550.CLDAP_11810	1.013e-39	155.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.11,2.7.8.41,2.7.8.5,2.7.8.8	ko:K00995,ko:K00999,ko:K08744,ko:K17103	ko00260,ko00562,ko00564,ko01100,ko01110,ko04070,map00260,map00562,map00564,map01100,map01110,map04070	M00093	R01800,R01801,R01802,R02030	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
ZZS3_k127_1466346_32	861299.J421_2183	1.549e-37	146.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1467328_3	861299.J421_1517	2.422e-42	168.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1467328_0	1123242.JH636436_gene366	1.013e-121	395.0	COG5649@1|root,COG5649@2|Bacteria,2IYNG@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
ZZS3_k127_1467328_1	1267533.KB906740_gene247	1.999e-115	385.0	COG1234@1|root,COG1234@2|Bacteria,3Y7KR@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
ZZS3_k127_1467328_4	861299.J421_5848	1.168e-40	152.0	2API8@1|root,31EM9@2|Bacteria,1ZV7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
ZZS3_k127_1467328_2	861299.J421_5847	1.266e-56	201.0	2E3HM@1|root,30MSF@2|Bacteria,1ZV6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1857532_24	562970.Btus_2307	4.317e-16	79.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,278KV@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
ZZS3_k127_1857532_16	484770.UFO1_1869	4.063e-38	145.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4H4SD@909932|Negativicutes	909932|Negativicutes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
ZZS3_k127_1857532_7	580327.Tthe_1801	3.138e-102	345.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
ZZS3_k127_1857532_2	1379270.AUXF01000006_gene86	5.202e-194	632.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1ZSWJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
ZZS3_k127_1857532_31	861299.J421_3443	1.551e-07	58.0	28U49@1|root,2ZGA9@2|Bacteria,1ZU72@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1857532_27	861299.J421_3442	2.471e-14	85.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
ZZS3_k127_1857532_3	861299.J421_3441	9.508e-190	605.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
ZZS3_k127_1857532_6	861299.J421_3440	4.553e-113	372.0	COG0190@1|root,COG0190@2|Bacteria,1ZSVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
ZZS3_k127_1857532_8	379066.GAU_1869	7.493e-85	295.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
ZZS3_k127_1857532_34	553385.JEMF01000021_gene3128	9.817e-06	54.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XM23@135619|Oceanospirillales	135619|Oceanospirillales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
ZZS3_k127_1857532_10	861299.J421_3437	4.52e-72	253.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
ZZS3_k127_1857532_1	861299.J421_3436	2.537e-250	792.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
ZZS3_k127_1857532_9	379066.GAU_1865	1.438e-73	258.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
ZZS3_k127_1857532_4	861299.J421_3434	2.153e-147	490.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
ZZS3_k127_1857532_11	1521187.JPIM01000083_gene3839	6.233e-64	237.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
ZZS3_k127_1857532_12	574375.BAGA_19825	8.59e-58	206.0	COG1670@1|root,COG1670@2|Bacteria,1V5WS@1239|Firmicutes,4HH37@91061|Bacilli,1ZEZG@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS3_k127_1857532_23	867903.ThesuDRAFT_01503	6.304e-19	94.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24IAA@186801|Clostridia	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_1857532_13	1131553.JIBI01000023_gene323	7.952e-45	173.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K17071	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,AAA_25,CHAT,HTH_17,MEDS,NB-ARC,TPR_12
ZZS3_k127_1857532_21	290400.Jann_3986	1.261e-22	102.0	COG0346@1|root,COG0346@2|Bacteria,1RCX8@1224|Proteobacteria	1224|Proteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_1857532_17	379066.GAU_2648	7.311e-37	142.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
ZZS3_k127_1857532_33	861299.J421_0091	5.779e-07	57.0	28XFN@1|root,2ZJD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1857532_28	926556.Echvi_1086	3.617e-09	63.0	2DT41@1|root,33IK2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1857532_22	446466.Cfla_0426	9.247e-22	100.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
ZZS3_k127_1857532_25	981369.JQMJ01000004_gene3647	8.029e-16	79.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
ZZS3_k127_1857532_29	568706.BN118_1034	5.044e-09	58.0	COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,2W38Q@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
ZZS3_k127_1857532_18	1379270.AUXF01000003_gene3588	6.176e-32	130.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
ZZS3_k127_1857532_26	1122611.KB903944_gene1107	1.925e-14	76.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4EKJI@85012|Streptosporangiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
ZZS3_k127_1857532_14	1298863.AUEP01000008_gene1211	2.385e-44	167.0	COG3189@1|root,COG3189@2|Bacteria	2|Bacteria	K	MarR family transcriptional regulator	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
ZZS3_k127_1857532_32	1192034.CAP_0901	2.191e-07	57.0	2E08V@1|root,32VWG@2|Bacteria,1N52T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1857532_5	330214.NIDE3598	2.682e-134	439.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
ZZS3_k127_1857532_15	483219.LILAB_15170	9.16e-40	150.0	COG4539@1|root,COG4539@2|Bacteria,1NXWT@1224|Proteobacteria,4384M@68525|delta/epsilon subdivisions,2X9XD@28221|Deltaproteobacteria,2YVQP@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
ZZS3_k127_1857532_0	861299.J421_3607	1.411e-295	919.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
ZZS3_k127_1857532_19	1415754.JQMK01000002_gene2982	3.347e-29	128.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,1S6DF@1236|Gammaproteobacteria,467X2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
ZZS3_k127_1857532_20	999541.bgla_1g11270	1.097e-28	121.0	COG3556@1|root,COG3556@2|Bacteria,1N3XH@1224|Proteobacteria,2VRQ4@28216|Betaproteobacteria,1K72R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
ZZS3_k127_188541_5	1192034.CAP_5739	2.789e-77	268.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZJK@68525|delta/epsilon subdivisions,2WV14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
ZZS3_k127_188541_8	861299.J421_2370	6.171e-29	124.0	2F95J@1|root,341H1@2|Bacteria,1ZTZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_188541_0	290397.Adeh_0062	2.08e-142	463.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_188541_4	644282.Deba_1222	2.71e-86	293.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS3_k127_188541_7	861299.J421_2367	1.63e-29	128.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_188541_3	671143.DAMO_2551	5.044e-97	337.0	COG1250@1|root,COG1250@2|Bacteria,2NP11@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
ZZS3_k127_188541_9	697282.Mettu_0887	3.003e-08	63.0	COG4244@1|root,COG4244@2|Bacteria,1NB74@1224|Proteobacteria,1SI9C@1236|Gammaproteobacteria,1XF4F@135618|Methylococcales	135618|Methylococcales	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
ZZS3_k127_188541_6	1157490.EL26_01200	1.645e-32	136.0	COG1852@1|root,COG1852@2|Bacteria,1V1B5@1239|Firmicutes,4HUDI@91061|Bacilli,279H3@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
ZZS3_k127_188541_2	861299.J421_2362	7.046e-103	354.0	COG0277@1|root,COG0277@2|Bacteria,1ZTB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
ZZS3_k127_188541_1	379066.GAU_0458	9.047e-113	368.0	COG1351@1|root,COG1351@2|Bacteria,1ZTEP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
ZZS3_k127_1950816_0	883080.HMPREF9697_00890	1.763e-151	488.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JX36@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
ZZS3_k127_1950816_3	379066.GAU_2909	1.774e-97	334.0	COG4319@1|root,COG4319@2|Bacteria,1ZUN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1950816_9	379066.GAU_2908	7.567e-23	108.0	2BFIU@1|root,329CS@2|Bacteria,1ZV5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1950816_12	1296415.JACC01000014_gene939	1.89e-05	57.0	COG1680@1|root,COG1680@2|Bacteria,4NGXR@976|Bacteroidetes,1HXN3@117743|Flavobacteriia,2YHYA@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_1950816_8	243230.DR_1710	1.924e-32	128.0	arCOG05253@1|root,31CTK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
ZZS3_k127_1950816_11	1173020.Cha6605_6085	1.097e-10	66.0	2CCNX@1|root,30VV4@2|Bacteria,1GG7R@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_1950816_6	1232437.KL662006_gene4388	8.596e-46	172.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
ZZS3_k127_1950816_10	518766.Rmar_1380	1.962e-12	70.0	COG3462@1|root,COG3462@2|Bacteria,4NVJQ@976|Bacteroidetes	976|Bacteroidetes	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
ZZS3_k127_1950816_7	1150399.AQYK01000002_gene3209	2.434e-41	170.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
ZZS3_k127_1950816_5	861299.J421_1614	1.758e-46	173.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	yjoA	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
ZZS3_k127_1950816_4	861299.J421_3721	1.794e-79	288.0	COG0747@1|root,COG0747@2|Bacteria,1ZUDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_1950816_2	379066.GAU_1136	1.877e-125	419.0	COG0408@1|root,COG0408@2|Bacteria,1ZUK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Coproporphyrinogen III oxidase	-	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
ZZS3_k127_1950816_1	379066.GAU_1137	7.385e-147	475.0	COG0407@1|root,COG0407@2|Bacteria,1ZTPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
ZZS3_k127_1950816_15	518766.Rmar_1891	0.0001124	47.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1FIQ0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
ZZS3_k127_1999156_0	861299.J421_2767	0.0	2054.0	COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
ZZS3_k127_1999156_1	1379270.AUXF01000004_gene3046	1.159e-63	218.0	COG0086@1|root,COG0303@1|root,COG0086@2|Bacteria,COG0303@2|Bacteria,1ZSZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
ZZS3_k127_2082409_0	861299.J421_2768	0.0	1205.0	COG0086@1|root,COG0086@2|Bacteria,1ZSZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
ZZS3_k127_2082409_5	1254432.SCE1572_33565	6.15e-91	310.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
ZZS3_k127_2082409_4	886293.Sinac_1472	4.089e-106	355.0	COG1131@1|root,COG1131@2|Bacteria,2IY2I@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_2082409_2	309807.SRU_0349	9.082e-181	602.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
ZZS3_k127_2082409_7	1379270.AUXF01000004_gene3043	7.086e-65	224.0	COG0048@1|root,COG0048@2|Bacteria,1ZTN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
ZZS3_k127_2082409_6	1379270.AUXF01000004_gene3042	1.296e-69	242.0	COG0049@1|root,COG0049@2|Bacteria,1ZSQZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
ZZS3_k127_2082409_3	861299.J421_5846	4.642e-119	409.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_2082409_1	316274.Haur_3277	1.183e-285	892.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi,374TQ@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS3_k127_2082409_8	644966.Tmar_2311	3.511e-33	128.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WCCR@538999|Clostridiales incertae sedis	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
ZZS3_k127_2128897_38	204669.Acid345_3584	4.451e-13	78.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_2128897_40	118005.AWNK01000010_gene411	4.403e-10	70.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF4440,SnoaL_2,SnoaL_3,YkuD
ZZS3_k127_2128897_6	1089551.KE386572_gene4425	2.296e-115	390.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2VE49@28211|Alphaproteobacteria,4BS35@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
ZZS3_k127_2128897_12	1089551.KE386572_gene1226	1.006e-72	258.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
ZZS3_k127_2128897_14	1089551.KE386572_gene1348	1.889e-68	254.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2128897_7	1089551.KE386572_gene4426	6.143e-97	336.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,2U12I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS3_k127_2128897_44	1038859.AXAU01000006_gene5626	6.822e-05	54.0	COG3554@1|root,COG3554@2|Bacteria,1RHFQ@1224|Proteobacteria,2U9RI@28211|Alphaproteobacteria,3JU9E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_43	44251.PDUR_02575	5.226e-05	54.0	2DBV7@1|root,2ZB9P@2|Bacteria,1UBN2@1239|Firmicutes,4HEYF@91061|Bacilli,26VBW@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
ZZS3_k127_2128897_29	1267534.KB906756_gene299	6.277e-30	127.0	29PQU@1|root,30AP1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
ZZS3_k127_2128897_34	460265.Mnod_5656	3.445e-21	96.0	2FDWQ@1|root,345X5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_11	296591.Bpro_1654	4.816e-73	249.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2W2JB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_2128897_4	1300345.LF41_1080	7.071e-142	471.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1XA6G@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_2	1499967.BAYZ01000109_gene2987	2.194e-183	593.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	rhbB	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
ZZS3_k127_2128897_5	1379270.AUXF01000001_gene1925	3.805e-117	389.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56,SHD1
ZZS3_k127_2128897_41	344747.PM8797T_00814	3.296e-07	57.0	COG2764@1|root,COG2764@2|Bacteria,2IZTY@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_2128897_18	378806.STAUR_4246	3.785e-52	199.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_19	1209989.TepiRe1_2165	8.586e-50	196.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
ZZS3_k127_2128897_10	1192034.CAP_8570	4.574e-73	262.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,43B2H@68525|delta/epsilon subdivisions,2X6GI@28221|Deltaproteobacteria,2YUTY@29|Myxococcales	28221|Deltaproteobacteria	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
ZZS3_k127_2128897_35	861299.J421_6009	2.291e-19	92.0	2E328@1|root,32Y2G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_13	1128421.JAGA01000002_gene1139	4.773e-72	248.0	COG3663@1|root,COG3663@2|Bacteria,2NRDF@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	mug	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.28,6.3.3.2	ko:K01934,ko:K03649	ko00670,ko01100,ko03410,map00670,map01100,map03410	-	R02301	RC00183	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS3_k127_2128897_20	690850.Desaf_3625	2.923e-49	183.0	COG3554@1|root,COG3554@2|Bacteria,1RA4K@1224|Proteobacteria	1224|Proteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
ZZS3_k127_2128897_31	977880.RALTA_A1142	9.037e-26	107.0	COG3615@1|root,COG3615@2|Bacteria,1QVHF@1224|Proteobacteria,2WH8F@28216|Betaproteobacteria,1KE3S@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Protein of unknown function (DUF3565)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3565
ZZS3_k127_2128897_32	290397.Adeh_0958	1.143e-23	105.0	2E8MZ@1|root,332ZD@2|Bacteria,1P763@1224|Proteobacteria,432M3@68525|delta/epsilon subdivisions,2WXF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_39	1219031.BBJR01000038_gene3135	3.396e-11	70.0	COG1917@1|root,COG1917@2|Bacteria,1NA8I@1224|Proteobacteria,2VVT4@28216|Betaproteobacteria,4AFFI@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_2128897_23	1242864.D187_007100	1.348e-45	171.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
ZZS3_k127_2128897_24	1123508.JH636447_gene8066	3.717e-45	171.0	COG1075@1|root,COG1075@2|Bacteria,2J1DE@203682|Planctomycetes	203682|Planctomycetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_33	1123256.KB907925_gene1085	1.933e-21	98.0	COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,1SC54@1236|Gammaproteobacteria,1X95C@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF202
ZZS3_k127_2128897_16	203275.BFO_1928	2.215e-57	213.0	2ES9V@1|root,33JUK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_8	375286.mma_2596	5.656e-91	303.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
ZZS3_k127_2128897_22	1157708.KB907459_gene2048	4.987e-47	174.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria,4AEDJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
ZZS3_k127_2128897_42	298655.KI912266_gene773	1.126e-06	57.0	COG4567@1|root,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
ZZS3_k127_2128897_36	234267.Acid_5764	1.56e-17	87.0	COG5552@1|root,COG5552@2|Bacteria,3Y864@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
ZZS3_k127_2128897_3	379066.GAU_3326	8.969e-167	533.0	COG2081@1|root,COG2081@2|Bacteria,1ZUAT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
ZZS3_k127_2128897_30	861299.J421_6306	1.964e-29	122.0	COG1734@1|root,COG1734@2|Bacteria,1ZV6D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_25	1121920.AUAU01000004_gene618	2.183e-43	165.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_2128897_37	1296416.JACB01000026_gene3964	1.765e-17	93.0	COG4319@1|root,COG4319@2|Bacteria,4NTMK@976|Bacteroidetes,1I929@117743|Flavobacteriia,2YJCD@290174|Aquimarina	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
ZZS3_k127_2128897_26	870187.Thini_0777	2.566e-40	151.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
ZZS3_k127_2128897_21	1041139.KB902702_gene2538	6.802e-48	177.0	2E930@1|root,333BZ@2|Bacteria,1Q8B7@1224|Proteobacteria,2VEHC@28211|Alphaproteobacteria,4BE2P@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2128897_28	983544.Lacal_2711	1.793e-32	137.0	COG1408@1|root,COG1408@2|Bacteria,4NKIS@976|Bacteroidetes,1I059@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
ZZS3_k127_2128897_1	670307.HYPDE_38393	3.898e-190	609.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C,Rieske
ZZS3_k127_2128897_0	1124780.ANNU01000008_gene2769	1.057e-234	742.0	COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,47TFT@768503|Cytophagia	976|Bacteroidetes	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
ZZS3_k127_2128897_9	1096546.WYO_3494	1.165e-86	293.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,1JSI3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
ZZS3_k127_2128897_27	1267535.KB906767_gene2392	2.167e-39	150.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
ZZS3_k127_2128897_15	1128421.JAGA01000001_gene2144	3.087e-62	220.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_2128897_17	595494.Tola_1283	1.304e-53	196.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1Y4T5@135624|Aeromonadales	135624|Aeromonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
ZZS3_k127_2189243_6	1192034.CAP_4860	5.084e-42	161.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YXMW@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG type nucleases (URI domain)	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	UVR
ZZS3_k127_2189243_5	379066.GAU_2434	2.479e-72	255.0	COG0266@1|root,COG0266@2|Bacteria,1ZU9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
ZZS3_k127_2189243_2	591001.Acfer_1276	1.744e-111	375.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
ZZS3_k127_2189243_4	379066.GAU_2432	8.088e-91	310.0	COG0501@1|root,COG0501@2|Bacteria,1ZT2E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
ZZS3_k127_2189243_0	861299.J421_3896	1.902e-161	517.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_2189243_3	379066.GAU_2430	5.478e-98	331.0	COG3437@1|root,COG3437@2|Bacteria,1ZSX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
ZZS3_k127_2189243_1	861299.J421_3894	4.247e-143	469.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_226310_15	861299.J421_0885	5.118e-78	284.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
ZZS3_k127_226310_7	861299.J421_1863	1.786e-117	413.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_226310_18	266779.Meso_2196	1.349e-69	244.0	COG0262@1|root,COG0262@2|Bacteria,1R7YJ@1224|Proteobacteria,2U43B@28211|Alphaproteobacteria,43KBN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS3_k127_226310_20	1352941.M877_21330	1.257e-65	227.0	COG3832@1|root,COG3832@2|Bacteria,2IFBH@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_226310_26	404589.Anae109_0512	1.21e-45	169.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
ZZS3_k127_226310_4	1379270.AUXF01000002_gene1586	1.806e-165	552.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1586|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_226310_10	1304865.JAGF01000001_gene234	4.687e-103	345.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria	201174|Actinobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
ZZS3_k127_226310_33	1194165.CAJF01000028_gene324	1.154e-09	66.0	COG2764@1|root,COG2764@2|Bacteria,2I2KY@201174|Actinobacteria,4FTN3@85023|Microbacteriaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_226310_5	861299.J421_0460	5.12e-145	477.0	COG1807@1|root,COG1807@2|Bacteria,1ZUFB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS3_k127_226310_30	1121033.AUCF01000001_gene1917	5.183e-24	108.0	COG0745@1|root,COG0745@2|Bacteria,1N9SP@1224|Proteobacteria,2UFA5@28211|Alphaproteobacteria,2JYZQ@204441|Rhodospirillales	204441|Rhodospirillales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_226310_19	42256.RradSPS_0598	8.431e-68	242.0	COG2514@1|root,COG2514@2|Bacteria,2GN1X@201174|Actinobacteria,4CSUF@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
ZZS3_k127_226310_14	639030.JHVA01000001_gene3935	4.871e-80	284.0	COG1680@1|root,COG1680@2|Bacteria,3Y7U9@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_226310_16	1227352.C173_27310	1.703e-76	267.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_226310_34	861299.J421_3153	1.146e-08	65.0	COG2304@1|root,COG2304@2|Bacteria,1ZTCZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
ZZS3_k127_226310_27	1167006.UWK_00742	1.045e-41	168.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
ZZS3_k127_226310_22	247490.KSU1_C0861	6.126e-61	224.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
ZZS3_k127_226310_32	36875.HQ29_05570	8.477e-11	75.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia,22XR6@171551|Porphyromonadaceae	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_226310_12	1499967.BAYZ01000069_gene1845	2.152e-88	306.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS3_k127_226310_6	1499967.BAYZ01000069_gene1846	1.062e-127	416.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS3_k127_226310_0	596151.DesfrDRAFT_4139	0.0	1156.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
ZZS3_k127_226310_13	316067.Geob_2771	1.456e-87	303.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_226310_17	404589.Anae109_1789	4.829e-76	274.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42S0Z@68525|delta/epsilon subdivisions,2WWFY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS3_k127_226310_31	869210.Marky_1116	5.221e-22	102.0	COG1510@1|root,COG1510@2|Bacteria,1WKHD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_226310_9	1379270.AUXF01000003_gene3555	1.682e-112	383.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_226310_28	861299.J421_6107	2.389e-35	144.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
ZZS3_k127_226310_21	1265313.HRUBRA_00432	1.321e-61	232.0	COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,1T0QH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG4257 Streptogramin lyase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
ZZS3_k127_226310_3	1089550.ATTH01000001_gene237	1.172e-173	566.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS3_k127_226310_1	404589.Anae109_3011	1.185e-272	857.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
ZZS3_k127_226310_8	379066.GAU_0756	2.813e-117	396.0	COG3104@1|root,COG3104@2|Bacteria,1ZSRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
ZZS3_k127_226310_35	981384.AEYW01000022_gene3619	2.897e-06	55.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4NDPT@97050|Ruegeria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HEAT_2,Rhodanese,TPR_16,TPR_19,TPR_8,TolB_N
ZZS3_k127_226310_2	861299.J421_6111	1.421e-266	841.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_226310_29	1128421.JAGA01000002_gene944	2.596e-34	147.0	COG0438@1|root,COG0438@2|Bacteria,2NR08@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_226310_24	1089551.KE386572_gene401	4.99e-57	219.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,4BSZB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
ZZS3_k127_226310_25	335543.Sfum_0958	1.969e-48	190.0	COG3919@1|root,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,42U1R@68525|delta/epsilon subdivisions,2X2JR@28221|Deltaproteobacteria,2MS8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_226310_11	338963.Pcar_2907	1.597e-93	316.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,42PZT@68525|delta/epsilon subdivisions,2WMN6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
ZZS3_k127_226310_23	1254432.SCE1572_45215	2.877e-57	220.0	COG0463@1|root,COG1541@1|root,COG0463@2|Bacteria,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glycos_transf_2
ZZS3_k127_2359358_15	1379270.AUXF01000002_gene1414	7.963e-17	83.0	COG0317@1|root,COG0317@2|Bacteria,1ZTKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
ZZS3_k127_2359358_5	1248916.ANFY01000009_gene105	3.301e-99	329.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2K21H@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
ZZS3_k127_2359358_7	215803.DB30_7393	1.345e-95	323.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,2Z04D@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
ZZS3_k127_2359358_6	671143.DAMO_2354	2.706e-96	324.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
ZZS3_k127_2359358_12	292459.STH2345	9.28e-27	119.0	COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,24G14@186801|Clostridia	186801|Clostridia	L	PFAM nuclease (SNase	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
ZZS3_k127_2359358_8	1379270.AUXF01000001_gene2718	1.971e-67	243.0	COG4454@1|root,COG4454@2|Bacteria,1ZTKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2359358_1	861299.J421_2179	2.006e-274	857.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS3_k127_2359358_4	926550.CLDAP_30780	3.087e-99	336.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G719@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
ZZS3_k127_2359358_17	379066.GAU_2601	0.0006451	50.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2359358_0	1379270.AUXF01000003_gene3807	1.007e-280	877.0	COG1166@1|root,COG1166@2|Bacteria,1ZST1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
ZZS3_k127_2359358_3	517417.Cpar_0368	1.696e-200	632.0	COG0372@1|root,COG0372@2|Bacteria,1FD5Z@1090|Chlorobi	1090|Chlorobi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ZZS3_k127_2359358_9	1121381.JNIV01000009_gene2346	4.73e-59	209.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
ZZS3_k127_2359358_13	765420.OSCT_0866	4.408e-25	119.0	2A48D@1|root,30STK@2|Bacteria,2GAP6@200795|Chloroflexi,376XA@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2359358_10	118005.AWNK01000003_gene2461	4.177e-38	149.0	COG0780@1|root,COG0780@2|Bacteria	2|Bacteria	G	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
ZZS3_k127_2359358_2	290397.Adeh_1417	1.575e-208	666.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_2359358_11	485913.Krac_3363	7.994e-35	141.0	COG1309@1|root,COG1309@2|Bacteria,2G9G4@200795|Chloroflexi	2|Bacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017,ko:K22295	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
ZZS3_k127_2359358_14	1121104.AQXH01000006_gene2309	2.107e-21	109.0	COG1629@1|root,COG2730@1|root,COG2730@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase,TonB_dep_Rec
ZZS3_k127_2359358_16	240016.ABIZ01000001_gene5183	8.843e-07	53.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,46SCB@74201|Verrucomicrobia,2ITTJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
ZZS3_k127_2373018_14	379066.GAU_0008	9.582e-99	330.0	COG0515@1|root,COG0515@2|Bacteria,1ZT9E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_2373018_20	379066.GAU_0007	1.636e-51	188.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
ZZS3_k127_2373018_33	234267.Acid_6913	2.314e-16	91.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	COXG,Polyketide_cyc2
ZZS3_k127_2373018_34	472759.Nhal_1932	1.542e-13	72.0	2E7PS@1|root,3325B@2|Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2373018_36	290397.Adeh_2026	1.332e-11	71.0	COG0537@1|root,COG0537@2|Bacteria,1NMG6@1224|Proteobacteria	1224|Proteobacteria	FG	adenosine 5'-monophosphoramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2373018_24	379066.GAU_3340	1.085e-45	170.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS3_k127_2373018_17	1052684.PPM_1323	4.875e-62	221.0	COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,26XPE@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the metal hydrolase YfiT family	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_2373018_15	886293.Sinac_3443	3.582e-76	258.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
ZZS3_k127_2373018_21	1121035.AUCH01000005_gene226	2.666e-51	184.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,2KWRH@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
ZZS3_k127_2373018_18	379066.GAU_0004	4.083e-56	208.0	COG2207@1|root,COG2207@2|Bacteria,1ZTPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS3_k127_2373018_5	379066.GAU_3750	3.89e-149	511.0	COG0515@1|root,COG0515@2|Bacteria,1ZURQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_2373018_31	314287.GB2207_11628	6.106e-17	84.0	2DMTH@1|root,32TKP@2|Bacteria,1N4TE@1224|Proteobacteria,1S9K6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2373018_3	861299.J421_1072	1.928e-177	562.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
ZZS3_k127_2373018_2	379066.GAU_0001	1.147e-180	578.0	COG0593@1|root,COG0593@2|Bacteria,1ZSQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
ZZS3_k127_2373018_30	1379270.AUXF01000002_gene1189	1.052e-17	84.0	COG0230@1|root,COG0230@2|Bacteria,1ZU59@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
ZZS3_k127_2373018_37	670487.Ocepr_0899	7.889e-06	54.0	COG0594@1|root,COG0594@2|Bacteria,1WKD9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
ZZS3_k127_2373018_27	1173264.KI913949_gene3743	2.628e-29	117.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1HCVK@1150|Oscillatoriales	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
ZZS3_k127_2373018_9	1379270.AUXF01000002_gene1186	5.376e-110	377.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
ZZS3_k127_2373018_10	379066.GAU_3931	1.045e-106	361.0	COG0486@1|root,COG0486@2|Bacteria,1ZSRA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
ZZS3_k127_2373018_8	1379270.AUXF01000002_gene1184	2.895e-112	373.0	COG5504@1|root,COG5504@2|Bacteria,1ZTCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2373018_26	861299.J421_0895	6.363e-32	137.0	COG0705@1|root,COG0705@2|Bacteria,1ZSWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ZZS3_k127_2373018_6	471852.Tcur_3455	9.745e-117	384.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4EI19@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
ZZS3_k127_2373018_1	1379270.AUXF01000002_gene1158	6.288e-182	586.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
ZZS3_k127_2373018_32	861299.J421_0898	7.879e-17	86.0	COG0810@1|root,COG0810@2|Bacteria,1ZV4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
ZZS3_k127_2373018_0	1379698.RBG1_1C00001G1138	1.036e-211	692.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
ZZS3_k127_2373018_11	1194972.MVAC_29348	2.543e-105	350.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,2329S@1762|Mycobacteriaceae	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
ZZS3_k127_2373018_22	713586.KB900536_gene2816	6.238e-49	179.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,1S6SD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_2373018_7	1303518.CCALI_01109	1.479e-116	387.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_2373018_29	861299.J421_2119	5.903e-20	101.0	COG0596@1|root,COG0596@2|Bacteria,1ZUCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Alpha/beta hydrolase family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
ZZS3_k127_2373018_35	1232410.KI421413_gene742	1.387e-12	80.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,42VYT@68525|delta/epsilon subdivisions,2WRFT@28221|Deltaproteobacteria,43T6X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_19,TPR_2,TPR_8
ZZS3_k127_2373018_12	404589.Anae109_3404	7.956e-105	358.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YUPC@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	crdA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_2373018_23	290397.Adeh_3342	3.436e-48	194.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
ZZS3_k127_2373018_38	864069.MicloDRAFT_00057370	6.393e-05	56.0	COG0747@1|root,COG0747@2|Bacteria,1PUV0@1224|Proteobacteria,2TVJT@28211|Alphaproteobacteria,1JZ2Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_2373018_28	861299.J421_0904	1.595e-20	104.0	COG1729@1|root,COG3087@1|root,COG1729@2|Bacteria,COG3087@2|Bacteria,1ZTSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_6
ZZS3_k127_2373018_19	379066.GAU_3913	3.643e-52	198.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
ZZS3_k127_2373018_16	1379270.AUXF01000002_gene1169	1.422e-63	224.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
ZZS3_k127_2373018_25	861299.J421_0929	2.5e-40	159.0	COG1434@1|root,COG1434@2|Bacteria,1ZTZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
ZZS3_k127_2373018_4	861299.J421_1939	1.701e-152	495.0	COG1236@1|root,COG1236@2|Bacteria,1ZSP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
ZZS3_k127_2373018_13	861299.J421_1060	4.168e-99	331.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
ZZS3_k127_2463611_5	1121472.AQWN01000003_gene1404	9.769e-24	102.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_2463611_8	639030.JHVA01000001_gene3299	7.684e-14	73.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria,2JJCY@204432|Acidobacteriia	204432|Acidobacteriia	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
ZZS3_k127_2463611_6	1297617.JPJD01000021_gene1440	4.063e-19	91.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,269IV@186813|unclassified Clostridiales	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
ZZS3_k127_2463611_7	861299.J421_3144	8.472e-16	87.0	COG1196@1|root,COG1196@2|Bacteria,1ZU4J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2463611_9	1246626.BleG1_1456	6.846e-11	66.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,1ZI3X@1386|Bacillus	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
ZZS3_k127_2463611_2	861299.J421_3146	1.459e-58	211.0	COG1994@1|root,COG1994@2|Bacteria,1ZTIB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
ZZS3_k127_2463611_0	861299.J421_3147	1.995e-66	237.0	COG1354@1|root,COG1354@2|Bacteria,1ZT1G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
ZZS3_k127_2463611_4	1034769.KB910518_gene1313	3.63e-31	129.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,26SV4@186822|Paenibacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
ZZS3_k127_2463611_1	861299.J421_3149	5.312e-59	214.0	COG1187@1|root,COG1187@2|Bacteria,1ZT5B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS3_k127_2463611_3	379066.GAU_1524	2.829e-32	128.0	COG0714@1|root,COG0714@2|Bacteria,1ZT94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS3_k127_2464546_1	861299.J421_3866	5.84e-108	375.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2464546_0	861299.J421_3864	1.53e-115	386.0	COG2804@1|root,COG2804@2|Bacteria,1ZT2F@142182|Gemmatimonadetes	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS3_k127_2497509_6	1123024.AUII01000035_gene1220	7.169e-43	162.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
ZZS3_k127_2497509_2	861299.J421_2612	5.694e-130	423.0	COG1063@1|root,COG1063@2|Bacteria,1ZSWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_2497509_1	1379270.AUXF01000004_gene3225	7.238e-177	562.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Beta-eliminating lyase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_2497509_5	379066.GAU_0655	3.816e-53	196.0	COG2094@1|root,COG2094@2|Bacteria,1ZTNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
ZZS3_k127_2497509_3	861299.J421_2605	3.758e-121	407.0	COG1432@1|root,COG1432@2|Bacteria,1ZSRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
ZZS3_k127_2497509_4	861299.J421_2500	7.103e-80	280.0	COG0642@1|root,COG0642@2|Bacteria,1ZTZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS3_k127_2497509_0	1379270.AUXF01000004_gene3319	6.456e-218	687.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_2497509_7	1121468.AUBR01000022_gene2771	4.419e-33	141.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,42J5P@68295|Thermoanaerobacterales	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_9,Response_reg,TPR_8
ZZS3_k127_2607276_17	1267534.KB906754_gene3897	1.687e-68	240.0	COG0122@1|root,COG0122@2|Bacteria,3Y30W@57723|Acidobacteria,2JHWW@204432|Acidobacteriia	204432|Acidobacteriia	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS3_k127_2607276_4	555088.DealDRAFT_2852	1.299e-187	599.0	COG0076@1|root,COG0076@2|Bacteria,1TSK0@1239|Firmicutes,24A90@186801|Clostridia	186801|Clostridia	E	pyridoxal-dependent decarboxylase	ddc	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
ZZS3_k127_2607276_0	861299.J421_3780	0.0	1158.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS3_k127_2607276_25	448385.sce5866	1.002e-17	95.0	COG0392@1|root,COG0392@2|Bacteria,1R959@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS3_k127_2607276_2	1379270.AUXF01000003_gene3673	2.299e-205	654.0	COG1132@1|root,COG1132@2|Bacteria,1ZSZC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
ZZS3_k127_2607276_23	215803.DB30_1069	2.239e-22	111.0	COG1716@1|root,COG1716@2|Bacteria,1QTBQ@1224|Proteobacteria,43F2N@68525|delta/epsilon subdivisions,2X34T@28221|Deltaproteobacteria,2YZ6W@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
ZZS3_k127_2607276_12	1379270.AUXF01000003_gene3674	1.536e-88	303.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS3_k127_2607276_18	379066.GAU_3234	7.669e-42	166.0	2DB97@1|root,32TX2@2|Bacteria,1ZUUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2607276_21	861299.J421_4416	8.831e-25	106.0	COG2261@1|root,COG2261@2|Bacteria,1ZV7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
ZZS3_k127_2607276_20	1144275.COCOR_02750	5.965e-35	141.0	COG0454@1|root,COG0456@2|Bacteria,1Q5AK@1224|Proteobacteria,43AJW@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,MarR,MarR_2
ZZS3_k127_2607276_26	378806.STAUR_3173	1.309e-12	72.0	28XFN@1|root,2ZJD7@2|Bacteria,1QSV2@1224|Proteobacteria,43E20@68525|delta/epsilon subdivisions,2X95Y@28221|Deltaproteobacteria,2Z23X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2607276_8	861299.J421_4397	1.86e-118	389.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yflN	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_2607276_19	861299.J421_4388	1.768e-39	152.0	COG3019@1|root,COG3019@2|Bacteria,1ZTWW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
ZZS3_k127_2607276_6	861299.J421_3775	8.41e-133	451.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
ZZS3_k127_2607276_1	1379270.AUXF01000003_gene3680	9.051e-223	703.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
ZZS3_k127_2607276_27	582515.KR51_00006960	8.467e-05	53.0	COG5549@1|root,COG5549@2|Bacteria,1G4CD@1117|Cyanobacteria	1117|Cyanobacteria	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
ZZS3_k127_2607276_11	861299.J421_3762	9.604e-97	327.0	COG0648@1|root,COG0648@2|Bacteria,1ZSY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
ZZS3_k127_2607276_24	644966.Tmar_0739	7.134e-18	94.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
ZZS3_k127_2607276_15	379066.GAU_2162	7.525e-80	282.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS3_k127_2607276_13	379066.GAU_2161	4.57e-81	279.0	COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Part of the ABC transporter FtsEX involved in	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
ZZS3_k127_2607276_16	1379270.AUXF01000003_gene3686	9.406e-80	273.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
ZZS3_k127_2607276_5	861299.J421_3758	1.319e-139	457.0	COG0626@1|root,COG0626@2|Bacteria,1ZUSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_2607276_22	861299.J421_3756	8.93e-25	113.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2607276_9	861299.J421_3755	8.036e-105	350.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2607276_10	861299.J421_3754	1.41e-100	338.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2607276_7	861299.J421_3753	3.665e-124	405.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ZZS3_k127_2607276_14	861299.J421_3752	2.129e-80	280.0	COG0859@1|root,COG0859@2|Bacteria,1ZSYI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
ZZS3_k127_2607276_3	428125.CLOLEP_01451	4.575e-190	604.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
ZZS3_k127_274836_8	744979.R2A130_2963	1.14e-27	119.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
ZZS3_k127_274836_14	1127134.NOCYR_0930	9.73e-06	53.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
ZZS3_k127_274836_6	1379270.AUXF01000002_gene1806	5.785e-53	194.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
ZZS3_k127_274836_16	379066.GAU_0469	6.71e-05	52.0	28UVI@1|root,2ZGZI@2|Bacteria,1ZU6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_274836_2	2074.JNYD01000022_gene1521	6.99e-92	312.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
ZZS3_k127_274836_4	570268.ANBB01000017_gene3847	8.974e-59	222.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ZZS3_k127_274836_10	391625.PPSIR1_29548	5.467e-16	88.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	3.4.19.5	ko:K03088,ko:K13051	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	DUF4440,SnoaL_3
ZZS3_k127_274836_0	2074.JNYD01000041_gene3370	5.258e-158	519.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4DX52@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
ZZS3_k127_274836_12	1034769.KB910518_gene3376	2e-11	78.0	COG3250@1|root,COG3867@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG3867@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1UNMG@1239|Firmicutes,4IUI8@91061|Bacilli,277MP@186822|Paenibacillaceae	91061|Bacilli	GN	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,SLH
ZZS3_k127_274836_9	1123487.KB892834_gene3049	2.636e-21	110.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KUUQ@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
ZZS3_k127_274836_1	861299.J421_2390	5.523e-121	397.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_274836_5	379066.GAU_0483	9.214e-54	198.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
ZZS3_k127_274836_15	1123248.KB893386_gene1819	2.396e-05	52.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1IXST@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_274836_13	1379270.AUXF01000002_gene1389	3.52e-08	65.0	2EY2H@1|root,33RBE@2|Bacteria,1ZTHK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_274836_11	379066.GAU_2806	1.784e-11	75.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
ZZS3_k127_274836_3	469383.Cwoe_4585	3.729e-71	250.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS3_k127_274836_7	1122604.JONR01000009_gene2366	7.631e-29	118.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1MWIC@1224|Proteobacteria,1RNX4@1236|Gammaproteobacteria,1X5R4@135614|Xanthomonadales	135614|Xanthomonadales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
ZZS3_k127_2780600_6	266117.Rxyl_0083	4.051e-121	402.0	COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_2780600_35	452637.Oter_3586	1.44e-17	90.0	COG1914@1|root,COG1914@2|Bacteria,46SH7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
ZZS3_k127_2780600_19	1379270.AUXF01000001_gene2649	5.099e-70	244.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
ZZS3_k127_2780600_30	379066.GAU_2716	7.406e-40	155.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS3_k127_2780600_36	1121445.ATUZ01000020_gene2178	6.164e-11	65.0	COG2331@1|root,COG2331@2|Bacteria,1NGC1@1224|Proteobacteria,42W5D@68525|delta/epsilon subdivisions,2WRAY@28221|Deltaproteobacteria,2MD4Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS3_k127_2780600_27	880073.Calab_0866	2.897e-52	195.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
ZZS3_k127_2780600_16	935863.AWZR01000014_gene2973	5.84e-76	267.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1X4TC@135614|Xanthomonadales	135614|Xanthomonadales	V	proteins, homologs of microcin C7 resistance protein MccF	ldcA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
ZZS3_k127_2780600_13	861299.J421_4371	2.799e-83	290.0	COG1215@1|root,COG1215@2|Bacteria,1ZU0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
ZZS3_k127_2780600_5	861299.J421_4374	7.495e-125	437.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
ZZS3_k127_2780600_33	365528.KB891238_gene5907	8.449e-27	128.0	COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2GM2V@201174|Actinobacteria	201174|Actinobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII,SNF2_N
ZZS3_k127_2780600_17	1192034.CAP_5445	1.167e-72	250.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2WZ2N@28221|Deltaproteobacteria,2Z16Z@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
ZZS3_k127_2780600_8	1123508.JH636446_gene6369	1.231e-107	384.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_2780600_29	1242864.D187_005988	4.374e-48	198.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QX74@1224|Proteobacteria,43AJN@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
ZZS3_k127_2780600_26	861299.J421_3846	6.955e-54	196.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
ZZS3_k127_2780600_4	379066.GAU_2373	5.946e-132	430.0	COG0306@1|root,COG0306@2|Bacteria,1ZSZ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
ZZS3_k127_2780600_15	1089548.KI783301_gene561	9.379e-77	271.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2780600_22	643562.Daes_2743	7.048e-65	228.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42SPM@68525|delta/epsilon subdivisions,2WMYY@28221|Deltaproteobacteria,2MAFZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
ZZS3_k127_2780600_0	867903.ThesuDRAFT_01477	7.97e-234	734.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,24Z0I@186801|Clostridia	186801|Clostridia	H	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
ZZS3_k127_2780600_24	251229.Chro_3582	8.789e-56	203.0	COG0637@1|root,COG0637@2|Bacteria,1GI36@1117|Cyanobacteria,3VMPN@52604|Pleurocapsales	1117|Cyanobacteria	S	HAD-hyrolase-like	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
ZZS3_k127_2780600_38	1379270.AUXF01000003_gene3389	0.0001156	53.0	COG4968@1|root,COG4968@2|Bacteria,1ZUZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS3_k127_2780600_21	357808.RoseRS_4327	5.442e-65	248.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi,375BC@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_8
ZZS3_k127_2780600_2	1379270.AUXF01000003_gene3597	1.662e-133	449.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993,ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	HlyD_3
ZZS3_k127_2780600_28	1379270.AUXF01000003_gene3596	5.042e-49	193.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_2780600_3	1379270.AUXF01000003_gene3595	1.171e-132	448.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ZZS3_k127_2780600_18	861299.J421_6160	1.123e-70	249.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6160|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
ZZS3_k127_2780600_1	861299.J421_4135	1.605e-208	678.0	COG0515@1|root,COG0515@2|Bacteria,1ZUAC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_2780600_25	861299.J421_1280	1.091e-55	223.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_2780600_31	92637.XP_007811308.1	3.373e-33	138.0	2EPDW@1|root,2SSKY@2759|Eukaryota,3APND@33154|Opisthokonta,3PFQI@4751|Fungi,3R8WR@4890|Ascomycota,21FP3@147550|Sordariomycetes,3TN72@5125|Hypocreales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2780600_7	378806.STAUR_7506	6.041e-112	377.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2X5HM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidase inhibitor I9	-	-	3.4.21.111	ko:K20754	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I9,Peptidase_S8
ZZS3_k127_2780600_34	608506.COB47_1223	3.724e-25	114.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,42GDW@68295|Thermoanaerobacterales	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
ZZS3_k127_2780600_9	1121920.AUAU01000010_gene46	1.338e-94	330.0	COG0165@1|root,COG0165@2|Bacteria,3Y36Y@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
ZZS3_k127_2780600_20	309807.SRU_2220	2.116e-67	243.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1FJRZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
ZZS3_k127_2780600_14	1121920.AUAU01000010_gene44	2.25e-80	279.0	COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
ZZS3_k127_2780600_12	1163408.UU9_11370	7.417e-87	299.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS3_k127_2780600_11	1121920.AUAU01000010_gene42	1.17e-90	313.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_2780600_23	518766.Rmar_0948	1.046e-59	220.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1FK0Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS3_k127_2780600_10	215803.DB30_7506	1.943e-93	318.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria,438QP@68525|delta/epsilon subdivisions,2X92A@28221|Deltaproteobacteria,2YXIK@29|Myxococcales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF1611_C) P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
ZZS3_k127_2785484_5	1173026.Glo7428_2422	6.246e-64	227.0	COG2148@1|root,COG2148@2|Bacteria,1G1P3@1117|Cyanobacteria	1117|Cyanobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS3_k127_2785484_1	743299.Acife_2930	3.611e-159	511.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,1RUDN@1236|Gammaproteobacteria,2NC3D@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2785484_2	330214.NIDE2988	1.095e-95	327.0	COG0438@1|root,COG0438@2|Bacteria,3J19R@40117|Nitrospirae	40117|Nitrospirae	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2785484_7	479434.Sthe_1158	2.75e-05	56.0	COG3307@1|root,COG3307@2|Bacteria,2G79D@200795|Chloroflexi,27Y8C@189775|Thermomicrobia	189775|Thermomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
ZZS3_k127_2785484_3	861299.J421_3482	2.003e-87	313.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_2785484_4	1245469.S58_08590	1.128e-68	251.0	COG2227@1|root,COG2227@2|Bacteria,1RCSH@1224|Proteobacteria,2U5XV@28211|Alphaproteobacteria,3JYCI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_2785484_0	489825.LYNGBM3L_15880	8.656e-225	711.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_2785484_6	102232.GLO73106DRAFT_00034670	1.389e-50	186.0	COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ZZS3_k127_298998_1	861299.J421_5759	1.701e-89	301.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_298998_0	1266925.JHVX01000002_gene936	1.291e-197	632.0	COG1404@1|root,COG1404@2|Bacteria,1R2W1@1224|Proteobacteria	1224|Proteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS3_k127_2990237_3	861299.J421_5846	2.889e-109	383.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_2990237_5	1255043.TVNIR_2862	1.004e-45	174.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_2990237_4	1267535.KB906767_gene1933	5.429e-47	174.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
ZZS3_k127_2990237_0	1267535.KB906767_gene1934	4.555e-175	561.0	2CA5R@1|root,2Z81H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
ZZS3_k127_2990237_1	1336243.JAEA01000009_gene175	3.713e-170	541.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTYY@28211|Alphaproteobacteria,1JSZJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_2990237_2	1379270.AUXF01000002_gene1761	2.645e-120	400.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS3_k127_2990237_6	491952.Mar181_2303	0.0004512	44.0	2EH8B@1|root,33B05@2|Bacteria,1NQEC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_34	887929.HMP0721_2517	3.873e-08	55.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_8	861299.J421_1859	2.795e-96	332.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
ZZS3_k127_3031207_13	861299.J421_1860	4.965e-65	238.0	COG0025@1|root,COG0025@2|Bacteria,1ZTCR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_16	530564.Psta_0826	4.924e-49	181.0	COG3685@1|root,COG3685@2|Bacteria,2IZPC@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
ZZS3_k127_3031207_6	379066.GAU_1743	1.892e-124	413.0	COG0534@1|root,COG0534@2|Bacteria,1ZUAU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
ZZS3_k127_3031207_30	649743.HMPREF0972_01776	1.53e-18	90.0	COG2314@1|root,COG2314@2|Bacteria,2GU27@201174|Actinobacteria	201174|Actinobacteria	M	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,TM2
ZZS3_k127_3031207_36	391615.ABSJ01000002_gene467	3.682e-06	48.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_18	861299.J421_1513	4.266e-47	179.0	2CWY1@1|root,32T0M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_28	525904.Tter_2777	1.366e-25	121.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6
ZZS3_k127_3031207_29	1267534.KB906754_gene3165	6.287e-19	93.0	COG2318@1|root,COG2318@2|Bacteria,3Y7B7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
ZZS3_k127_3031207_17	861299.J421_3204	3.843e-48	184.0	COG0127@1|root,COG0127@2|Bacteria,1ZTSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
ZZS3_k127_3031207_11	1379270.AUXF01000005_gene838	2.897e-84	287.0	COG0689@1|root,COG0689@2|Bacteria,1ZSYT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
ZZS3_k127_3031207_19	379066.GAU_1570	7.005e-46	172.0	COG0615@1|root,COG0615@2|Bacteria,1ZTPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
ZZS3_k127_3031207_7	886293.Sinac_0383	6.569e-100	345.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
ZZS3_k127_3031207_21	861299.J421_3201	2.372e-42	160.0	2EPTK@1|root,33HE4@2|Bacteria,1ZTUK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
ZZS3_k127_3031207_35	861299.J421_3200	9.842e-07	59.0	2F5A9@1|root,33XWF@2|Bacteria,1ZTU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_4	1379698.RBG1_1C00001G1445	4.998e-146	499.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
ZZS3_k127_3031207_22	1379270.AUXF01000005_gene834	1.423e-40	171.0	COG0652@1|root,COG0652@2|Bacteria,1ZUUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS3_k127_3031207_25	861299.J421_3199	3.76e-32	131.0	COG0824@1|root,COG0824@2|Bacteria,1ZTY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
ZZS3_k127_3031207_24	861299.J421_3198	5.867e-37	149.0	COG2908@1|root,COG2908@2|Bacteria,1ZTNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
ZZS3_k127_3031207_9	861299.J421_3197	2.2e-94	318.0	COG0796@1|root,COG0796@2|Bacteria,1ZUQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
ZZS3_k127_3031207_33	379066.GAU_1564	2.331e-09	66.0	2FIMZ@1|root,34ADU@2|Bacteria,1ZTYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3031207_20	861299.J421_3195	1.387e-43	162.0	COG0251@1|root,COG0251@2|Bacteria,1ZTSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
ZZS3_k127_3031207_1	246194.CHY_2385	1.286e-220	696.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42FHK@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM formate-tetrahydrofolate ligase FTHFS	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
ZZS3_k127_3031207_14	861299.J421_3194	8.188e-64	231.0	COG0084@1|root,COG0084@2|Bacteria,1ZST0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ZZS3_k127_3031207_12	861299.J421_3193	4.419e-79	274.0	COG0341@1|root,COG0341@2|Bacteria,1ZSSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
ZZS3_k127_3031207_3	1379270.AUXF01000005_gene826	1.122e-162	529.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
ZZS3_k127_3031207_10	861299.J421_3191	6.132e-90	313.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
ZZS3_k127_3031207_15	269800.Tfu_0781	3.283e-54	203.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4EGVA@85012|Streptosporangiales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
ZZS3_k127_3031207_27	696281.Desru_1900	7.517e-27	114.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,262H0@186807|Peptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
ZZS3_k127_3031207_32	1348663.KCH_53030	2.422e-13	74.0	COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria,2M36Y@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
ZZS3_k127_3031207_0	379066.GAU_1556	4.138e-289	913.0	COG0532@1|root,COG0532@2|Bacteria,1ZT5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
ZZS3_k127_3031207_31	861299.J421_3187	1.761e-13	74.0	COG1358@1|root,COG1358@2|Bacteria,1ZU1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
ZZS3_k127_3031207_2	379066.GAU_1554	4.637e-198	626.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
ZZS3_k127_3031207_26	379066.GAU_1553	3.557e-30	126.0	COG0779@1|root,COG0779@2|Bacteria,1ZTX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
ZZS3_k127_3031207_23	379066.GAU_1552	3.229e-39	159.0	COG1496@1|root,COG1496@2|Bacteria,1ZTTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
ZZS3_k127_3031207_5	379066.GAU_1551	4.158e-129	417.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
ZZS3_k127_3052954_9	861299.J421_3392	1.353e-66	239.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
ZZS3_k127_3052954_16	385682.AFSL01000040_gene245	1.182e-05	53.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_3052954_5	861299.J421_3391	3.846e-123	410.0	COG0124@1|root,COG0124@2|Bacteria,1ZSXX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
ZZS3_k127_3052954_0	861299.J421_3390	3.34e-217	683.0	COG0442@1|root,COG0442@2|Bacteria,1ZT48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
ZZS3_k127_3052954_6	795359.TOPB45_0697	2.68e-109	387.0	COG0019@1|root,COG0019@2|Bacteria,2GHHY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
ZZS3_k127_3052954_1	269799.Gmet_2292	3.266e-204	648.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,43SA0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
ZZS3_k127_3052954_15	518766.Rmar_2301	6.889e-06	59.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_2301|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3052954_13	379066.GAU_1741	6.692e-59	209.0	COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
ZZS3_k127_3052954_4	861299.J421_3385	1.005e-127	416.0	COG0042@1|root,COG0042@2|Bacteria,1ZSQC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
ZZS3_k127_3052954_7	1303518.CCALI_01219	8.675e-77	267.0	COG1691@1|root,COG1691@2|Bacteria	2|Bacteria	C	(AIR) carboxylase	cpmA	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
ZZS3_k127_3052954_8	635013.TherJR_1274	8.282e-74	259.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,261JI@186807|Peptococcaceae	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ZZS3_k127_3052954_14	1458427.BAWN01000013_gene875	1.085e-30	138.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2WEQB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
ZZS3_k127_3052954_12	1379270.AUXF01000002_gene1173	8.047e-63	236.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
ZZS3_k127_3052954_2	861299.J421_4340	6.007e-157	507.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS3_k127_3052954_3	1123368.AUIS01000029_gene1282	4.284e-146	473.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,2NBXD@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
ZZS3_k127_3052954_11	1123368.AUIS01000029_gene1283	2.604e-64	228.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,2NCU3@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
ZZS3_k127_3052954_10	479434.Sthe_0770	2.124e-64	223.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,27Y4S@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS3_k127_3060275_3	1038860.AXAP01000099_gene5323	4.843e-43	162.0	COG2259@1|root,COG2259@2|Bacteria,1PU63@1224|Proteobacteria,2V5XZ@28211|Alphaproteobacteria,3K41K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
ZZS3_k127_3060275_4	1869.MB27_20610	1.143e-15	81.0	COG4191@1|root,COG4191@2|Bacteria,2IF7B@201174|Actinobacteria	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
ZZS3_k127_3060275_6	96561.Dole_0109	2.248e-09	68.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria,2MNJG@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
ZZS3_k127_3060275_0	1242864.D187_004920	2.652e-206	655.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
ZZS3_k127_3060275_5	68170.KL590548_gene3330	8.309e-15	80.0	COG4191@1|root,COG4191@2|Bacteria,2GZ7K@201174|Actinobacteria,4E8PU@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
ZZS3_k127_3060275_1	861299.J421_3854	5.05e-112	375.0	COG0544@1|root,COG0544@2|Bacteria,1ZSSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
ZZS3_k127_3060275_2	883156.HMPREF9282_00267	2.974e-82	277.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4H2XP@909932|Negativicutes	909932|Negativicutes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ZZS3_k127_306593_12	518766.Rmar_0984	2.19e-34	138.0	COG2166@1|root,COG2166@2|Bacteria,4PF5T@976|Bacteroidetes,1FK6U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
ZZS3_k127_306593_1	266117.Rxyl_0687	7.918e-141	461.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
ZZS3_k127_306593_8	68260.JOAY01000001_gene3599	8.491e-87	301.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
ZZS3_k127_306593_11	1394178.AWOO02000043_gene5853	1.675e-49	194.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4EHBR@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
ZZS3_k127_306593_4	1254432.SCE1572_20990	7.904e-120	392.0	COG0604@1|root,COG0604@2|Bacteria,1R2DZ@1224|Proteobacteria,43DM8@68525|delta/epsilon subdivisions,2X65T@28221|Deltaproteobacteria,2Z39E@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_306593_7	414684.RC1_1149	5.354e-88	311.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2JQM2@204441|Rhodospirillales	204441|Rhodospirillales	P	Sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
ZZS3_k127_306593_9	338963.Pcar_1476	8.127e-69	255.0	28N9P@1|root,2ZBDN@2|Bacteria,1R70P@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
ZZS3_k127_306593_15	861299.J421_6150	2.866e-32	132.0	2DF6S@1|root,2ZQP7@2|Bacteria,1ZU7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_306593_2	886293.Sinac_1729	5.963e-133	436.0	COG0501@1|root,COG0501@2|Bacteria,2J0GY@203682|Planctomycetes	203682|Planctomycetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
ZZS3_k127_306593_17	1392838.AWNM01000071_gene529	4.29e-11	66.0	2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,2VXSE@28216|Betaproteobacteria,3T850@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
ZZS3_k127_306593_13	870187.Thini_0382	1.044e-32	129.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales	72273|Thiotrichales	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
ZZS3_k127_306593_5	945713.IALB_0211	2.413e-110	369.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
ZZS3_k127_306593_16	1121403.AUCV01000009_gene1455	3.941e-29	122.0	COG3899@1|root,COG4191@1|root,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2WJNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,Pkinase
ZZS3_k127_306593_14	525904.Tter_0607	2.401e-32	130.0	29EH1@1|root,336FM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_306593_10	479434.Sthe_3392	1.24e-53	202.0	COG3058@1|root,COG3058@2|Bacteria,2G9S5@200795|Chloroflexi,27YFM@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
ZZS3_k127_306593_6	479434.Sthe_3390	1.365e-98	332.0	COG3301@1|root,COG3301@2|Bacteria,2GA0G@200795|Chloroflexi,27YBQ@189775|Thermomicrobia	189775|Thermomicrobia	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
ZZS3_k127_306593_3	479434.Sthe_3389	1.98e-130	425.0	COG0437@1|root,COG0437@2|Bacteria,2G9ZX@200795|Chloroflexi,27Y09@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S binding domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3
ZZS3_k127_306593_0	479434.Sthe_3388	3.713e-290	898.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G62W@200795|Chloroflexi,27YXY@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
ZZS3_k127_3104778_10	1267534.KB906754_gene3897	2.337e-52	188.0	COG0122@1|root,COG0122@2|Bacteria,3Y30W@57723|Acidobacteria,2JHWW@204432|Acidobacteriia	204432|Acidobacteriia	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS3_k127_3104778_20	1123248.KB893332_gene2283	3.519e-22	97.0	2E301@1|root,32Y0K@2|Bacteria,4NWAM@976|Bacteroidetes,1IU60@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3072)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3072
ZZS3_k127_3104778_12	1173020.Cha6605_1048	7.19e-49	180.0	COG1670@1|root,COG1670@2|Bacteria,1GA76@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
ZZS3_k127_3104778_22	1396141.BATP01000051_gene3338	5.406e-11	69.0	2EKH8@1|root,33E79@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3104778_2	479435.Kfla_2739	2.466e-131	430.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4DQ2D@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_3104778_3	1173025.GEI7407_1418	1.287e-117	383.0	2CK2M@1|root,32UWE@2|Bacteria,1GEG1@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3104778_19	1173025.GEI7407_1419	4.696e-28	117.0	29A69@1|root,2ZX7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3104778_23	697281.Mahau_0077	1.604e-07	54.0	COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia,42HVJ@68295|Thermoanaerobacterales	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3104778_9	861299.J421_3797	9.226e-59	218.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
ZZS3_k127_3104778_11	1449065.JMLL01000017_gene3997	1.756e-49	181.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,43JN0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
ZZS3_k127_3104778_18	861299.J421_3799	4.738e-31	131.0	COG0741@1|root,COG0741@2|Bacteria,1ZTV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
ZZS3_k127_3104778_8	338963.Pcar_2042	4.026e-80	290.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43S23@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
ZZS3_k127_3104778_21	861299.J421_3801	6.334e-12	72.0	2960H@1|root,2ZTB5@2|Bacteria,1ZU7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3104778_17	1121438.JNJA01000015_gene1303	1.179e-31	133.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,42U9T@68525|delta/epsilon subdivisions,2WQPQ@28221|Deltaproteobacteria,2MCJT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
ZZS3_k127_3104778_6	592015.HMPREF1705_02114	4.18e-99	332.0	COG0115@1|root,COG0115@2|Bacteria,3T9VI@508458|Synergistetes	508458|Synergistetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ZZS3_k127_3104778_7	1120934.KB894424_gene1239	2.521e-90	306.0	COG1409@1|root,COG1409@2|Bacteria,2GIT1@201174|Actinobacteria,4E0S4@85010|Pseudonocardiales	201174|Actinobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS3_k127_3104778_0	379066.GAU_0705	4.31e-158	506.0	COG0798@1|root,COG0798@2|Bacteria	2|Bacteria	P	PFAM Bile acid sodium symporter	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	iYO844.BSU25790	SBF
ZZS3_k127_3104778_4	42256.RradSPS_3006	3.319e-112	370.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
ZZS3_k127_3104778_16	861299.J421_2257	9.524e-35	138.0	COG1246@1|root,COG1246@2|Bacteria,1ZV2J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
ZZS3_k127_3104778_5	1267535.KB906767_gene5005	8.412e-112	374.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
ZZS3_k127_3104778_15	861299.J421_2255	5.278e-36	139.0	COG0640@1|root,COG0640@2|Bacteria,1ZV07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
ZZS3_k127_3104778_13	1283299.AUKG01000001_gene3429	5.619e-42	157.0	COG0025@1|root,COG0025@2|Bacteria,2I2S7@201174|Actinobacteria	201174|Actinobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
ZZS3_k127_3104778_1	221288.JH992901_gene2423	2.493e-133	430.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3104778_14	861299.J421_0827	1.83e-37	146.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	catD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
ZZS3_k127_3119717_2	861299.J421_3829	4.197e-109	362.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
ZZS3_k127_3119717_10	861299.J421_3830	1.237e-60	229.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3119717_9	379066.GAU_2351	1.083e-65	233.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
ZZS3_k127_3119717_11	861299.J421_3833	1.175e-54	206.0	COG0566@1|root,COG0566@2|Bacteria,1ZTVA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNA 2'-O ribose methyltransferase substrate binding	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
ZZS3_k127_3119717_8	1123389.ATXJ01000006_gene2225	8.66e-75	271.0	COG0351@1|root,COG0351@2|Bacteria,1WIN0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
ZZS3_k127_3119717_7	379066.GAU_2354	9.982e-82	300.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
ZZS3_k127_3119717_1	204669.Acid345_3056	1.439e-145	476.0	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria,2JIKE@204432|Acidobacteriia	204432|Acidobacteriia	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
ZZS3_k127_3119717_3	379066.GAU_2355	2.177e-104	352.0	COG1816@1|root,COG1816@2|Bacteria,1ZSQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
ZZS3_k127_3119717_14	379066.GAU_2356	8.958e-06	57.0	290N8@1|root,2ZNAK@2|Bacteria,1ZU7A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3119717_0	1379270.AUXF01000003_gene3570	2.984e-194	650.0	COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
ZZS3_k127_3119717_13	1229172.JQFA01000007_gene13	2.315e-10	70.0	COG2827@1|root,COG2827@2|Bacteria,1G9KB@1117|Cyanobacteria,1HFTH@1150|Oscillatoriales	1117|Cyanobacteria	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
ZZS3_k127_3119717_12	1379270.AUXF01000001_gene2712	1.075e-11	71.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
ZZS3_k127_3119717_5	379066.GAU_2359	3.722e-94	319.0	COG0745@1|root,COG0745@2|Bacteria,1ZTC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_3119717_6	379066.GAU_2360	9.8e-93	325.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
ZZS3_k127_3119717_15	1279009.ADICEAN_03704	0.0003529	53.0	COG3746@1|root,COG3746@2|Bacteria,4NG5Z@976|Bacteroidetes,47MFQ@768503|Cytophagia	976|Bacteroidetes	P	PFAM Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
ZZS3_k127_3119717_4	204669.Acid345_2975	6.411e-101	335.0	COG0226@1|root,COG0226@2|Bacteria,3Y399@57723|Acidobacteria,2JIVU@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
ZZS3_k127_3141291_41	1124780.ANNU01000019_gene1696	4.592e-11	71.0	2DS15@1|root,33E22@2|Bacteria,4NYSK@976|Bacteroidetes,47WV4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3141291_43	391587.KAOT1_02912	1.55e-07	64.0	COG1807@1|root,COG4642@1|root,COG1807@2|Bacteria,COG4642@2|Bacteria,4PME4@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	MORN
ZZS3_k127_3141291_21	251229.Chro_3389	1.138e-61	220.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
ZZS3_k127_3141291_4	1386089.N865_16495	3.869e-191	610.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4FIJ7@85021|Intrasporangiaceae	201174|Actinobacteria	I	Carboxylesterase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
ZZS3_k127_3141291_18	452863.Achl_3336	3.333e-64	225.0	COG4635@1|root,COG4635@2|Bacteria,2INN9@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
ZZS3_k127_3141291_8	66874.JOFS01000001_gene897	1.258e-141	468.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
ZZS3_k127_3141291_14	1267533.KB906741_gene569	2.288e-73	253.0	COG0262@1|root,COG0262@2|Bacteria,3Y4XB@57723|Acidobacteria,2JMZH@204432|Acidobacteriia	204432|Acidobacteriia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS3_k127_3141291_37	1458357.BG58_05730	6.922e-15	82.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,1K202@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
ZZS3_k127_3141291_6	1206741.BAFX01000135_gene1745	9.32e-183	616.0	COG2132@1|root,COG3055@1|root,COG2132@2|Bacteria,COG3055@2|Bacteria,2GK14@201174|Actinobacteria,4FUXU@85025|Nocardiaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929
ZZS3_k127_3141291_5	365046.Rta_06820	8.208e-183	581.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
ZZS3_k127_3141291_7	365046.Rta_06880	1.214e-162	519.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,2W01H@28216|Betaproteobacteria,4AGE3@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
ZZS3_k127_3141291_9	504472.Slin_6549	8.011e-136	454.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS3_k127_3141291_12	319003.Bra1253DRAFT_07535	1.74e-110	366.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria,3JRZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
ZZS3_k127_3141291_36	1121403.AUCV01000019_gene3315	6.363e-15	81.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1N0KJ@1224|Proteobacteria,42YX7@68525|delta/epsilon subdivisions,2WUG8@28221|Deltaproteobacteria,2MMI5@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3141291_39	1210884.HG799462_gene8794	8.095e-13	76.0	COG4191@1|root,COG4191@2|Bacteria,2J2PC@203682|Planctomycetes	203682|Planctomycetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
ZZS3_k127_3141291_25	861299.J421_6150	3.886e-49	180.0	2DF6S@1|root,2ZQP7@2|Bacteria,1ZU7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3141291_33	1192034.CAP_3674	1.566e-22	109.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
ZZS3_k127_3141291_0	861299.J421_0254	1.112e-310	961.0	COG0405@1|root,COG0405@2|Bacteria,1ZUIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS3_k127_3141291_11	1123248.KB893327_gene788	3.448e-112	372.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
ZZS3_k127_3141291_34	864069.MicloDRAFT_00003280	2.746e-20	96.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria,2U808@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Alkylated DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
ZZS3_k127_3141291_38	658086.HMPREF0994_05609	7.092e-14	79.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,27IKU@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
ZZS3_k127_3141291_35	316067.Geob_3387	3.763e-20	97.0	COG0745@1|root,COG0745@2|Bacteria,1R9AR@1224|Proteobacteria,42YHD@68525|delta/epsilon subdivisions,2WU58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ZZS3_k127_3141291_13	639282.DEFDS_P186	1.821e-82	299.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,2GEP8@200930|Deferribacteres	200930|Deferribacteres	T	two-component system, chemotaxis family, sensor kinase CheA with response regulator domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
ZZS3_k127_3141291_32	316067.Geob_3385	2.426e-31	130.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42QS2@68525|delta/epsilon subdivisions,2WMXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS3_k127_3141291_20	316067.Geob_3384	7.704e-63	235.0	COG0840@1|root,COG1511@1|root,COG0840@2|Bacteria,COG1511@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2WM8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
ZZS3_k127_3141291_44	290397.Adeh_3966	9.969e-06	59.0	COG1413@1|root,COG1413@2|Bacteria,1QAUN@1224|Proteobacteria,435B4@68525|delta/epsilon subdivisions,2WZNB@28221|Deltaproteobacteria,2Z2F0@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS3_k127_3141291_42	521011.Mpal_2732	2.246e-08	67.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
ZZS3_k127_3141291_23	243231.GSU2215	2.792e-53	198.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,43UG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
ZZS3_k127_3141291_15	891968.Anamo_0287	3.807e-72	258.0	COG2201@1|root,COG2201@2|Bacteria,3T9RD@508458|Synergistetes	508458|Synergistetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
ZZS3_k127_3141291_16	404589.Anae109_2831	1.879e-65	226.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_3141291_30	1267534.KB906758_gene2322	1.068e-32	132.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_3141291_17	1122611.KB903963_gene4645	1.335e-64	231.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4EQYN@85012|Streptosporangiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_3141291_2	1242864.D187_005776	1.147e-209	657.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_3141291_19	420324.KI911999_gene8063	5.415e-64	231.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2U77A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3141291_10	420324.KI911999_gene8062	1.587e-133	431.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_3141291_26	1123393.KB891328_gene523	9.286e-49	184.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VMVW@28216|Betaproteobacteria,1KRXJ@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
ZZS3_k127_3141291_31	436308.Nmar_0233	5.02e-32	130.0	COG3324@1|root,arCOG04946@2157|Archaea,41T3T@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_3141291_27	296591.Bpro_1367	2.485e-44	167.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2VV8S@28216|Betaproteobacteria,4AHZ3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_3141291_1	861299.J421_4119	4.198e-220	691.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ZZS3_k127_3141291_22	290397.Adeh_2244	2.147e-54	198.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria	1224|Proteobacteria	S	Doxx family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
ZZS3_k127_3141291_24	883080.HMPREF9697_03372	1.657e-52	187.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria,3JYUE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
ZZS3_k127_3141291_3	296591.Bpro_1369	1.044e-203	646.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VJHX@28216|Betaproteobacteria,4ACRX@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
ZZS3_k127_3141291_29	861299.J421_3014	3.5e-35	143.0	2DJKR@1|root,32X86@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3141291_28	1242864.D187_009316	8.27e-38	154.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_3144914_3	1379270.AUXF01000005_gene516	6.064e-25	111.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
ZZS3_k127_3144914_0	861299.J421_0444	1.084e-196	625.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
ZZS3_k127_3144914_2	861299.J421_0446	2.952e-30	131.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3144914_1	861299.J421_0447	1.592e-67	234.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS3_k127_31751_9	379066.GAU_0717	1.384e-24	105.0	COG0355@1|root,COG0355@2|Bacteria,1ZU1K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
ZZS3_k127_31751_1	861299.J421_2629	5.068e-247	773.0	COG0055@1|root,COG0055@2|Bacteria,1ZSNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ZZS3_k127_31751_3	861299.J421_2628	4.054e-104	347.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
ZZS3_k127_31751_0	861299.J421_2627	3.944e-247	772.0	COG0056@1|root,COG0056@2|Bacteria,1ZSNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
ZZS3_k127_31751_8	1379270.AUXF01000004_gene3175	1.462e-37	151.0	COG2207@1|root,COG2207@2|Bacteria,1ZUCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS3_k127_31751_7	861299.J421_2626	1.888e-51	187.0	COG1051@1|root,COG1051@2|Bacteria,1ZTP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ZZS3_k127_31751_5	1379270.AUXF01000007_gene1059	2.228e-67	242.0	COG1463@1|root,COG1463@2|Bacteria,1ZUJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS3_k127_31751_6	1353537.TP2_03345	5.014e-61	219.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2XMAG@285107|Thioclava	28211|Alphaproteobacteria	Q	Organic solvent ABC transporter ATP-binding protein	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS3_k127_31751_4	379066.GAU_3855	4.784e-77	265.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS3_k127_31751_2	861299.J421_2624	9.043e-125	407.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_31751_10	1461580.CCAS010000118_gene4580	1.143e-08	59.0	2DDW9@1|root,2ZJJ8@2|Bacteria,1W4EI@1239|Firmicutes,4I1RT@91061|Bacilli,1ZK7C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_18	1385515.N791_00485	8.962e-51	193.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1X3UU@135614|Xanthomonadales	135614|Xanthomonadales	E	decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
ZZS3_k127_3197670_23	926569.ANT_27300	8.06e-42	164.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS3_k127_3197670_33	309807.SRU_2828	1.546e-26	115.0	2DBIE@1|root,32ZYG@2|Bacteria,4PM6T@976|Bacteroidetes,1FJJR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_34	290397.Adeh_2397	8.004e-26	118.0	COG1277@1|root,COG1277@2|Bacteria,1PK2D@1224|Proteobacteria,437V7@68525|delta/epsilon subdivisions,2WWIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
ZZS3_k127_3197670_25	290397.Adeh_2399	4.079e-37	154.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,430KF@68525|delta/epsilon subdivisions,2WW09@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
ZZS3_k127_3197670_17	452637.Oter_1805	9.26e-52	206.0	COG3420@1|root,COG3420@2|Bacteria,46VQ1@74201|Verrucomicrobia,3K7SA@414999|Opitutae	414999|Opitutae	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
ZZS3_k127_3197670_20	1089550.ATTH01000001_gene473	1.849e-50	189.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1FJJY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
ZZS3_k127_3197670_1	452637.Oter_1803	8.44e-269	849.0	COG4263@1|root,COG4263@2|Bacteria,46YT5@74201|Verrucomicrobia,3K7SZ@414999|Opitutae	414999|Opitutae	C	Cupredoxin-like domain	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
ZZS3_k127_3197670_37	290397.Adeh_2403	2.932e-19	94.0	COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_3197670_5	1089552.KI911559_gene1116	4.238e-138	459.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2JQYE@204441|Rhodospirillales	204441|Rhodospirillales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
ZZS3_k127_3197670_36	1304872.JAGC01000009_gene448	9.095e-21	97.0	arCOG08935@1|root,338YH@2|Bacteria,1N8JH@1224|Proteobacteria,43DKA@68525|delta/epsilon subdivisions,2WSNG@28221|Deltaproteobacteria,2MDSR@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_40	1114856.C496_04028	1.629e-15	81.0	arCOG11495@1|root,arCOG11495@2157|Archaea,2XZAM@28890|Euryarchaeota,23XCX@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_30	1429046.RR21198_1254	9.605e-32	131.0	2CK59@1|root,32VV2@2|Bacteria,2I7N7@201174|Actinobacteria,4G9UM@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_41	471857.Svir_17480	8.553e-15	80.0	COG0517@1|root,COG0517@2|Bacteria,2IMU7@201174|Actinobacteria,4E67Q@85010|Pseudonocardiales	201174|Actinobacteria	S	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
ZZS3_k127_3197670_38	765910.MARPU_16045	3.123e-19	94.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS3_k127_3197670_32	1242864.D187_009505	3.534e-29	133.0	COG3303@1|root,COG3303@2|Bacteria,1MYBV@1224|Proteobacteria,42SER@68525|delta/epsilon subdivisions,2WPC2@28221|Deltaproteobacteria,2YUR5@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
ZZS3_k127_3197670_43	243233.MCA2189	5.288e-11	76.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,1T3FX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
ZZS3_k127_3197670_42	404589.Anae109_3110	3.446e-13	83.0	COG3303@1|root,COG3303@2|Bacteria,1NNDS@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_0	1167006.UWK_03288	2.435e-301	944.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria,2MPSR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
ZZS3_k127_3197670_29	1317122.ATO12_08385	2.585e-32	140.0	COG3043@1|root,COG3043@2|Bacteria,4NG82@976|Bacteroidetes,1HZDY@117743|Flavobacteriia,2YHZ9@290174|Aquimarina	976|Bacteroidetes	C	Nitrate reductase cytochrome c-type subunit (NapB)	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	Cytochrome_C554,NapB
ZZS3_k127_3197670_35	616991.JPOO01000003_gene1679	4.271e-24	111.0	28JYU@1|root,2Z9NZ@2|Bacteria,4NKTR@976|Bacteroidetes,1I0RC@117743|Flavobacteriia,23G5C@178469|Arenibacter	976|Bacteroidetes	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
ZZS3_k127_3197670_7	1443665.JACA01000001_gene2625	9.887e-129	422.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia,2YH5Q@290174|Aquimarina	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
ZZS3_k127_3197670_4	1349785.BAUG01000008_gene667	1.641e-155	502.0	COG5557@1|root,COG5557@2|Bacteria,4NG2Z@976|Bacteroidetes,1I0YA@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
ZZS3_k127_3197670_13	382464.ABSI01000010_gene3739	2.444e-82	287.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
ZZS3_k127_3197670_39	1379270.AUXF01000002_gene1476	8.698e-18	93.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_31	290397.Adeh_0932	4.004e-31	132.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WPAC@28221|Deltaproteobacteria,2YW13@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS3_k127_3197670_2	1394178.AWOO02000012_gene3773	3.019e-179	579.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ZZS3_k127_3197670_19	1279009.ADICEAN_02287	1.638e-50	192.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ZZS3_k127_3197670_10	266779.Meso_2458	1.699e-104	346.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
ZZS3_k127_3197670_14	266117.Rxyl_2941	2.53e-67	236.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
ZZS3_k127_3197670_9	187303.BN69_0140	1.668e-110	366.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2U247@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_3197670_3	1123024.AUII01000010_gene684	5.077e-164	528.0	COG0477@1|root,COG2814@2|Bacteria,2GNBV@201174|Actinobacteria,4E2F7@85010|Pseudonocardiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_3197670_22	1146883.BLASA_3316	2.421e-45	171.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
ZZS3_k127_3197670_16	1303518.CCALI_00307	2.5e-56	205.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	nosZ	-	1.1.9.1,1.7.2.4	ko:K00376,ko:K02305,ko:K17760	ko00910,ko01120,map00910,map01120	M00529	R00294,R02804	RC02794,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	Beta_helix,Cupredoxin_1,Cytochrom_C,Cytochrome_CBB3,DUF1080,GSDH,HupE_UreJ_2,PSCyt1
ZZS3_k127_3197670_11	748280.NH8B_0760	3.039e-101	349.0	COG2132@1|root,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2VK95@28216|Betaproteobacteria,2KQAW@206351|Neisseriales	206351|Neisseriales	M	Nitrite reductase, copper-dependent	nirK	-	1.3.3.5,1.7.2.1	ko:K00368,ko:K08100	ko00860,ko00910,ko01110,ko01120,map00860,map00910,map01110,map01120	M00529	R00783,R00785,R02394	RC00086,RC01983	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3
ZZS3_k127_3197670_15	861299.J421_4188	7.14e-64	225.0	COG0221@1|root,COG0221@2|Bacteria,1ZTH9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
ZZS3_k127_3197670_6	1111069.TCCBUS3UF1_14350	1.764e-131	429.0	COG4864@1|root,COG4864@2|Bacteria,1WI32@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
ZZS3_k127_3197670_12	937777.Deipe_2634	4.87e-89	310.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
ZZS3_k127_3197670_45	861299.J421_3329	4.662e-09	65.0	297VI@1|root,2ZV24@2|Bacteria,1ZU61@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_24	379066.GAU_1695	2.896e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,1ZTKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_3197670_21	1379270.AUXF01000006_gene195	2.6e-49	184.0	COG0584@1|root,COG0584@2|Bacteria,1ZTTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS3_k127_3197670_44	861299.J421_3335	4.617e-09	62.0	2FG3A@1|root,347ZW@2|Bacteria,1ZV50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3197670_26	111780.Sta7437_4372	7.536e-37	140.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,3VK9B@52604|Pleurocapsales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
ZZS3_k127_3197670_28	379066.GAU_1699	7.266e-33	132.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
ZZS3_k127_3197670_8	1379698.RBG1_1C00001G0983	1.501e-112	385.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
ZZS3_k127_3197670_27	861299.J421_3340	1.427e-33	130.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_3205461_7	1379270.AUXF01000002_gene1820	2.482e-143	468.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
ZZS3_k127_3205461_13	379066.GAU_3864	2.79e-63	237.0	COG0515@1|root,COG3170@1|root,COG0515@2|Bacteria,COG3170@2|Bacteria,1ZTGA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_3205461_20	1379698.RBG1_1C00001G1442	1.353e-28	124.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
ZZS3_k127_3205461_14	498761.HM1_0704	4.253e-60	223.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
ZZS3_k127_3205461_5	379066.GAU_2783	4.979e-159	509.0	COG0276@1|root,COG0276@2|Bacteria,1ZTW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
ZZS3_k127_3205461_10	861299.J421_0272	3.556e-77	265.0	COG2197@1|root,COG2197@2|Bacteria,1ZTJ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_3205461_2	861299.J421_0271	9.948e-213	682.0	COG4585@1|root,COG4585@2|Bacteria,1ZSM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
ZZS3_k127_3205461_3	105559.Nwat_1701	1.447e-207	661.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS3_k127_3205461_16	396588.Tgr7_2359	5.246e-48	196.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA
ZZS3_k127_3205461_9	697281.Mahau_0321	7.619e-94	325.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,42EJW@68295|Thermoanaerobacterales	186801|Clostridia	GM	PFAM Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
ZZS3_k127_3205461_1	204669.Acid345_1535	3.799e-228	717.0	COG1012@1|root,COG1012@2|Bacteria,3Y384@57723|Acidobacteria,2JIA8@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85	ko:K00128,ko:K00130,ko:K00146,ko:K10217	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00555,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_3205461_11	1169161.KB897714_gene6205	2.498e-75	268.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
ZZS3_k127_3205461_6	204669.Acid345_1534	5.913e-149	486.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	57723|Acidobacteria	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_3205461_4	1121406.JAEX01000002_gene760	2.156e-170	545.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,42MZ8@68525|delta/epsilon subdivisions,2WMM3@28221|Deltaproteobacteria,2MG24@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_3205461_19	1121930.AQXG01000005_gene584	6.914e-32	133.0	2CDZB@1|root,3340J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3205461_0	1123392.AQWL01000002_gene1978	1.285e-312	988.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
ZZS3_k127_3205461_22	1276756.AUEX01000004_gene2510	2.293e-10	73.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,4AA86@80864|Comamonadaceae	28216|Betaproteobacteria	M	RND efflux system, outer membrane lipoprotein, NodT family	oprM_3	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
ZZS3_k127_3205461_15	1121033.AUCF01000010_gene4442	1.151e-59	228.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
ZZS3_k127_3205461_8	1379270.AUXF01000001_gene2469	5.433e-117	396.0	COG2866@1|root,COG2866@2|Bacteria,1ZT9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS3_k127_3205461_12	861299.J421_2921	4.662e-72	250.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
ZZS3_k127_3205461_23	195253.Syn6312_0128	7.958e-07	57.0	COG3794@1|root,COG3794@2|Bacteria,1G63W@1117|Cyanobacteria,1H497@1129|Synechococcus	1117|Cyanobacteria	C	Plastocyanin	petE	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
ZZS3_k127_3205461_17	861299.J421_2405	5.59e-48	194.0	COG0840@1|root,COG0840@2|Bacteria,1ZSWC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
ZZS3_k127_3205461_18	1379270.AUXF01000002_gene1824	2.428e-41	168.0	COG0683@1|root,COG0683@2|Bacteria,1ZSQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ZZS3_k127_3205461_21	404589.Anae109_2532	4.035e-28	114.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales	28221|Deltaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS3_k127_3335347_0	479434.Sthe_0672	7.176e-183	584.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	200795|Chloroflexi	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
ZZS3_k127_3335347_4	861299.J421_1804	3.914e-79	274.0	COG0730@1|root,COG0730@2|Bacteria,1ZU67@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_3335347_6	710685.MycrhN_4147	7.71e-50	185.0	COG0607@1|root,COG0607@2|Bacteria,2IB6H@201174|Actinobacteria,2335A@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
ZZS3_k127_3335347_7	1379270.AUXF01000002_gene1598	2.777e-30	124.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
ZZS3_k127_3335347_8	1047013.AQSP01000131_gene1844	5.9e-11	72.0	COG1238@1|root,COG1238@2|Bacteria	2|Bacteria	I	metal cluster binding	yqaA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
ZZS3_k127_3335347_9	929712.KI912613_gene1107	1.97e-05	57.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
ZZS3_k127_3335347_5	1286106.MPL1_02313	7.33e-56	199.0	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
ZZS3_k127_3335347_2	1297742.A176_00270	2.147e-88	309.0	COG2823@1|root,COG5637@1|root,COG2823@2|Bacteria,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,437A8@68525|delta/epsilon subdivisions,2X2EK@28221|Deltaproteobacteria,2YVIY@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
ZZS3_k127_3335347_3	861299.J421_4094	7.135e-87	299.0	COG5637@1|root,COG5637@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
ZZS3_k127_3335347_1	134676.ACPL_1345	4.032e-181	580.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DH1Z@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
ZZS3_k127_3372468_1	383372.Rcas_0232	9.265e-101	334.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
ZZS3_k127_3372468_2	861299.J421_2448	1.263e-99	342.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,1ZTZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS3_k127_3372468_5	661478.OP10G_3830	2.244e-27	117.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
ZZS3_k127_3372468_3	379066.GAU_0538	2.678e-76	269.0	COG0596@1|root,COG0596@2|Bacteria,1ZTAV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_6
ZZS3_k127_3372468_0	1379270.AUXF01000002_gene1859	1.101e-151	500.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1ZTG4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5
ZZS3_k127_3372468_4	861299.J421_2443	2.916e-49	181.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
ZZS3_k127_3421095_5	1379270.AUXF01000006_gene180	1.658e-75	258.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
ZZS3_k127_3421095_7	224324.aq_199	4.654e-59	223.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	yocB	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
ZZS3_k127_3421095_10	671143.DAMO_0482	9.287e-32	135.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
ZZS3_k127_3421095_6	861299.J421_3347	3.196e-65	225.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
ZZS3_k127_3421095_0	379066.GAU_1707	2.044e-249	784.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
ZZS3_k127_3421095_4	1519464.HY22_01960	5.162e-90	332.0	COG1404@1|root,COG1404@2|Bacteria,1FEZ9@1090|Chlorobi	1090|Chlorobi	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS3_k127_3421095_1	1379270.AUXF01000006_gene185	6.423e-212	668.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
ZZS3_k127_3421095_9	861299.J421_3344	5.863e-44	164.0	2CIU6@1|root,32S8H@2|Bacteria,1ZTUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3421095_8	1330700.JQNC01000003_gene960	4.801e-53	201.0	COG1024@1|root,COG1024@2|Bacteria,1WIUH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
ZZS3_k127_3421095_12	861299.J421_1299	6.351e-25	112.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
ZZS3_k127_3421095_3	1379270.AUXF01000006_gene190	8.073e-103	358.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
ZZS3_k127_3421095_2	379066.GAU_1701	1.132e-193	610.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_3421095_11	861299.J421_3338	1.591e-30	122.0	COG1530@1|root,COG1530@2|Bacteria,1ZSZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
ZZS3_k127_3455568_5	1379270.AUXF01000006_gene119	1.081e-106	353.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
ZZS3_k127_3455568_10	887929.HMP0721_0725	6.614e-67	233.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,25V66@186806|Eubacteriaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
ZZS3_k127_3455568_8	379066.GAU_1774	1.111e-91	306.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ZZS3_k127_3455568_11	379066.GAU_1773	5.296e-65	227.0	COG0233@1|root,COG0233@2|Bacteria,1ZTI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
ZZS3_k127_3455568_7	861299.J421_3408	1.136e-99	334.0	COG0020@1|root,COG0020@2|Bacteria,1ZSNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
ZZS3_k127_3455568_15	861299.J421_3407	4.684e-46	183.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
ZZS3_k127_3455568_6	1121468.AUBR01000029_gene1579	9.674e-102	345.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,42F80@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
ZZS3_k127_3455568_9	522306.CAP2UW1_2869	6.172e-70	254.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KQ8B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
ZZS3_k127_3455568_16	1379270.AUXF01000006_gene129	6.553e-29	123.0	COG0184@1|root,COG0184@2|Bacteria,1ZU0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
ZZS3_k127_3455568_0	861299.J421_3401	6.047e-298	930.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ZZS3_k127_3455568_4	861299.J421_3400	3.573e-131	430.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS3_k127_3455568_2	861299.J421_3399	1.235e-165	544.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
ZZS3_k127_3455568_14	1248760.ANFZ01000006_gene2322	5.267e-48	177.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
ZZS3_k127_3455568_1	861299.J421_3398	4.946e-187	591.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ZZS3_k127_3455568_13	1379270.AUXF01000006_gene134	3.862e-49	190.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
ZZS3_k127_3455568_17	861299.J421_3396	1.344e-24	111.0	2CIX2@1|root,33ZZP@2|Bacteria,1ZTZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
ZZS3_k127_3455568_3	1379270.AUXF01000006_gene136	1.079e-162	533.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
ZZS3_k127_3455568_12	379066.GAU_1757	3.656e-59	211.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
ZZS3_k127_3527024_48	886293.Sinac_5868	2.259e-45	174.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS3_k127_3527024_3	861299.J421_1876	5.206e-215	684.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS3_k127_3527024_53	861299.J421_1875	2.644e-35	141.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
ZZS3_k127_3527024_61	861299.J421_1875	1.872e-29	123.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
ZZS3_k127_3527024_68	1205680.CAKO01000029_gene5260	5.204e-21	102.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
ZZS3_k127_3527024_76	644282.Deba_3004	5.474e-11	72.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42X22@68525|delta/epsilon subdivisions,2WSMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
ZZS3_k127_3527024_79	697282.Mettu_1630	9.159e-05	48.0	2CN2H@1|root,32SG5@2|Bacteria,1N4PY@1224|Proteobacteria,1SESE@1236|Gammaproteobacteria,1XGHH@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3527024_57	1340493.JNIF01000003_gene2361	1.265e-31	128.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_3527024_73	1120959.ATXF01000005_gene1554	1.046e-13	81.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
ZZS3_k127_3527024_69	1348583.ATLH01000017_gene2670	1.34e-19	102.0	COG3291@1|root,COG3291@2|Bacteria,4PKJH@976|Bacteroidetes,1IJAY@117743|Flavobacteriia,1FAMT@104264|Cellulophaga	976|Bacteroidetes	E	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PKD
ZZS3_k127_3527024_10	1379270.AUXF01000005_gene526	7.008e-149	476.0	COG0462@1|root,COG0462@2|Bacteria,1ZT7Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
ZZS3_k127_3527024_50	861299.J421_2966	1.426e-43	167.0	COG1825@1|root,COG1825@2|Bacteria,1ZTHZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
ZZS3_k127_3527024_46	1379270.AUXF01000005_gene524	1.042e-46	174.0	COG0193@1|root,COG0193@2|Bacteria,1ZTKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
ZZS3_k127_3527024_15	997346.HMPREF9374_2493	2.301e-135	440.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,27BBQ@186824|Thermoactinomycetaceae	91061|Bacilli	J	Protein of unknown function (DUF933)	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
ZZS3_k127_3527024_42	479434.Sthe_0904	1.542e-56	212.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_3527024_49	383372.Rcas_4314	7.042e-45	179.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_3527024_64	1379270.AUXF01000005_gene514	1.114e-27	121.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
ZZS3_k127_3527024_65	379066.GAU_1205	3.721e-25	106.0	COG0238@1|root,COG0238@2|Bacteria,1ZU47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
ZZS3_k127_3527024_67	861299.J421_2951	3.778e-23	111.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
ZZS3_k127_3527024_54	880073.Calab_2408	4.087e-35	146.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
ZZS3_k127_3527024_26	882.DVU_1942	1.129e-97	344.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,42U2G@68525|delta/epsilon subdivisions,2WQBG@28221|Deltaproteobacteria,2M8TG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Dihydroxyacetone kinase family	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
ZZS3_k127_3527024_55	861299.J421_2949	6.853e-34	134.0	COG0799@1|root,COG0799@2|Bacteria,1ZU0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
ZZS3_k127_3527024_0	861299.J421_2948	2.253e-288	919.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
ZZS3_k127_3527024_59	379066.GAU_1196	2.77e-30	136.0	COG3087@1|root,COG3087@2|Bacteria,1ZSYS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
ZZS3_k127_3527024_1	861299.J421_2945	9.648e-272	875.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
ZZS3_k127_3527024_12	861299.J421_2942	7.155e-144	464.0	COG2876@1|root,COG2876@2|Bacteria,1ZTB0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ZZS3_k127_3527024_62	861299.J421_2941	5.001e-29	124.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
ZZS3_k127_3527024_52	484770.UFO1_0437	1.123e-39	159.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,4H47T@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
ZZS3_k127_3527024_14	861299.J421_2940	3.989e-141	467.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
ZZS3_k127_3527024_51	319795.Dgeo_1983	1.923e-40	163.0	COG0125@1|root,COG0125@2|Bacteria,1WK3U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
ZZS3_k127_3527024_70	861299.J421_2938	6.966e-19	91.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
ZZS3_k127_3527024_45	1379270.AUXF01000005_gene497	2.056e-47	181.0	COG2890@1|root,COG2890@2|Bacteria,1ZTQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
ZZS3_k127_3527024_17	861299.J421_2936	1.795e-132	430.0	COG0216@1|root,COG0216@2|Bacteria,1ZSNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS3_k127_3527024_66	443143.GM18_4160	1.032e-24	105.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,43VM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
ZZS3_k127_3527024_39	1379270.AUXF01000005_gene495	2.075e-61	219.0	COG0664@1|root,COG0664@2|Bacteria,1ZTHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
ZZS3_k127_3527024_37	1396141.BATP01000003_gene5111	9.085e-65	233.0	COG0745@1|root,COG1235@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,COG2203@2|Bacteria,46UKB@74201|Verrucomicrobia,2IVU2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Response_reg
ZZS3_k127_3527024_75	215803.DB30_7335	1.579e-12	78.0	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,FlgT_C
ZZS3_k127_3527024_27	861299.J421_2931	1.284e-97	342.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
ZZS3_k127_3527024_30	379066.GAU_1177	2.116e-86	298.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS3_k127_3527024_38	861299.J421_2928	3.71e-63	233.0	COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
ZZS3_k127_3527024_44	861299.J421_2925	1.212e-51	193.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
ZZS3_k127_3527024_6	1519464.HY22_09795	3.932e-176	562.0	COG2873@1|root,COG2873@2|Bacteria,1FDPZ@1090|Chlorobi	1090|Chlorobi	H	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
ZZS3_k127_3527024_36	1254432.SCE1572_08930	3.553e-65	226.0	COG0288@1|root,COG0288@2|Bacteria,1R3SC@1224|Proteobacteria,434U6@68525|delta/epsilon subdivisions,2WZ54@28221|Deltaproteobacteria,2Z1CJ@29|Myxococcales	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
ZZS3_k127_3527024_34	584708.Apau_1920	3.65e-74	263.0	COG2021@1|root,COG2021@2|Bacteria,3TAC1@508458|Synergistetes	508458|Synergistetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
ZZS3_k127_3527024_13	861299.J421_2922	5.08e-143	459.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_3527024_2	861299.J421_2920	8.675e-264	828.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
ZZS3_k127_3527024_71	379066.GAU_1167	1.716e-18	91.0	2FCTB@1|root,344W9@2|Bacteria,1ZU4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3527024_5	379066.GAU_1166	6.358e-189	605.0	COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_3527024_58	429009.Adeg_1729	1.661e-30	134.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,42H6P@68295|Thermoanaerobacterales	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
ZZS3_k127_3527024_35	861299.J421_2914	7.961e-74	258.0	COG1606@1|root,COG1606@2|Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
ZZS3_k127_3527024_56	1121439.dsat_1841	7.727e-33	132.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2MBZF@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
ZZS3_k127_3527024_74	1288494.EBAPG3_13890	9.86e-13	79.0	COG3103@1|root,COG3103@2|Bacteria,1NQ5X@1224|Proteobacteria,2WA5G@28216|Betaproteobacteria,372RR@32003|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM SH3, type 3	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
ZZS3_k127_3527024_31	1266925.JHVX01000003_gene499	2.474e-86	308.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2WGWX@28216|Betaproteobacteria,37279@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
ZZS3_k127_3527024_8	1151122.AQYD01000006_gene2341	8.183e-162	529.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria	201174|Actinobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
ZZS3_k127_3527024_4	671143.DAMO_3080	2.159e-198	632.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
ZZS3_k127_3527024_29	861299.J421_2940	9.77e-87	307.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
ZZS3_k127_3527024_7	379066.GAU_1150	5.544e-164	563.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS3_k127_3527024_41	861299.J421_2906	1.963e-59	213.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
ZZS3_k127_3527024_32	861299.J421_2904	5.671e-78	281.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS3_k127_3527024_21	861299.J421_2903	4e-112	376.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
ZZS3_k127_3527024_23	1379270.AUXF01000005_gene454	1.793e-109	368.0	COG0577@1|root,COG0577@2|Bacteria,1ZSU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_3527024_25	861299.J421_2900	5.296e-107	364.0	COG0577@1|root,COG0577@2|Bacteria,1ZUN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_3527024_9	861299.J421_1415	4.499e-161	517.0	COG0577@1|root,COG0577@2|Bacteria,1ZUG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_3527024_16	1379270.AUXF01000005_gene449	9.481e-135	447.0	COG0577@1|root,COG0577@2|Bacteria,1ZUCK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_3527024_40	861299.J421_5612	3.215e-60	218.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
ZZS3_k127_3527024_28	1379270.AUXF01000005_gene405	3.443e-88	297.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
ZZS3_k127_3527024_24	861299.J421_2892	6.164e-109	370.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ZZS3_k127_3527024_18	861299.J421_2891	4.683e-132	430.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
ZZS3_k127_3527024_63	1429046.RR21198_0466	2.708e-28	120.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria,4G28G@85025|Nocardiaceae	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
ZZS3_k127_3527024_19	379066.GAU_1124	2.427e-130	427.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
ZZS3_k127_3527024_60	861299.J421_2889	1.424e-29	126.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
ZZS3_k127_3527024_20	379066.GAU_1122	3.562e-123	409.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
ZZS3_k127_3527024_47	1379270.AUXF01000005_gene391	1.694e-46	179.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ZZS3_k127_3527024_22	379066.GAU_1116	1.672e-111	372.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
ZZS3_k127_3527024_43	861299.J421_2885	1.251e-55	203.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
ZZS3_k127_3527024_72	1379270.AUXF01000005_gene388	1.242e-16	88.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3527024_33	379066.GAU_1114	2.731e-75	257.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
ZZS3_k127_3527024_77	1246474.ANBE01000024_gene1686	2.555e-09	67.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4EJFI@85012|Streptosporangiales	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
ZZS3_k127_3527024_11	861299.J421_2881	1.618e-147	487.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
ZZS3_k127_3527024_78	1109445.AGSX01000186_gene2370	6.49e-08	64.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1Z0Y5@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	membrane	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ZZS3_k127_3561397_4	479434.Sthe_3388	1.766e-48	177.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G62W@200795|Chloroflexi,27YXY@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
ZZS3_k127_3561397_0	525904.Tter_0612	2.107e-233	731.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2NQFR@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
ZZS3_k127_3561397_2	479434.Sthe_3388	1.33e-83	281.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G62W@200795|Chloroflexi,27YXY@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
ZZS3_k127_3561397_3	1144275.COCOR_03628	3.593e-63	228.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS3_k127_3561397_1	1267534.KB906756_gene683	3.647e-111	371.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	ko:K03420,ko:K13525,ko:K17681	ko03050,ko04141,ko05134,map03050,map04141,map05134	M00343,M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko03029,ko03051,ko04131,ko04147	3.A.16.1	-	-	AAA
ZZS3_k127_3578168_1	1267535.KB906767_gene2627	6.731e-102	340.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
ZZS3_k127_3578168_0	1278073.MYSTI_07566	3.869e-184	589.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
ZZS3_k127_3578168_2	1123508.JH636444_gene5539	7.116e-97	335.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_3578168_3	861299.J421_1280	3.966e-18	100.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_3622729_13	197221.22294795	6.151e-14	72.0	COG0740@1|root,COG0740@2|Bacteria,1G126@1117|Cyanobacteria	1117|Cyanobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP3	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ZZS3_k127_3622729_1	861299.J421_3856	5.204e-217	679.0	COG1219@1|root,COG1219@2|Bacteria,1ZT8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
ZZS3_k127_3622729_9	861299.J421_3858	2.079e-42	165.0	COG0218@1|root,COG0218@2|Bacteria,1ZTHF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
ZZS3_k127_3622729_12	1379270.AUXF01000003_gene3510	3.936e-17	91.0	2F4EZ@1|root,33X55@2|Bacteria,1ZTSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3622729_0	861299.J421_4036	2.499e-243	771.0	COG4774@1|root,COG4774@2|Bacteria,1ZTSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
ZZS3_k127_3622729_2	861299.J421_3861	1.777e-101	338.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
ZZS3_k127_3622729_4	326427.Cagg_2013	2.472e-79	292.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
ZZS3_k127_3622729_11	1382356.JQMP01000001_gene1018	6.363e-35	152.0	COG3420@1|root,COG3420@2|Bacteria,2GBD6@200795|Chloroflexi,27YVB@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
ZZS3_k127_3622729_3	1236959.BAMT01000006_gene445	1.072e-84	291.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,2KM4T@206350|Nitrosomonadales	206350|Nitrosomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS3_k127_3622729_10	861299.J421_3863	5.144e-41	158.0	COG0494@1|root,COG0494@2|Bacteria,1ZTYK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
ZZS3_k127_3622729_8	1121468.AUBR01000017_gene2363	1.058e-48	184.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,42G87@68295|Thermoanaerobacterales	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS3_k127_3622729_5	1408164.MOLA814_02371	3.842e-70	243.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,1KPX0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
ZZS3_k127_3622729_6	760568.Desku_1692	5.555e-69	249.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,2606W@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_3622729_7	314345.SPV1_05527	2.285e-60	222.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria	1224|Proteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
ZZS3_k127_3834133_15	861299.J421_4120	3.585e-63	224.0	COG3544@1|root,COG3544@2|Bacteria,1ZTPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
ZZS3_k127_3834133_1	861299.J421_4121	7.107e-268	844.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
ZZS3_k127_3834133_22	479434.Sthe_2969	1.237e-29	131.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS3_k127_3834133_13	1123326.JFBL01000017_gene2279	7.681e-80	274.0	COG3193@1|root,COG3193@2|Bacteria,1R215@1224|Proteobacteria	1224|Proteobacteria	S	protein possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
ZZS3_k127_3834133_7	379066.GAU_0239	5.395e-144	469.0	2E0UX@1|root,32WC9@2|Bacteria,1ZUE1@142182|Gemmatimonadetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
ZZS3_k127_3834133_9	1379270.AUXF01000002_gene1599	3.24e-115	392.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1599|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_4	1121939.L861_16975	1.051e-176	563.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,1XN6Y@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,TPR_2
ZZS3_k127_3834133_18	861299.J421_2147	3.121e-42	158.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_3834133_20	383372.Rcas_1566	1.099e-31	131.0	2EB79@1|root,3357W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_23	760568.Desku_0882	4.841e-27	127.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,2617G@186807|Peptococcaceae	186801|Clostridia	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,LTD,Lactamase_B
ZZS3_k127_3834133_26	1501230.ET33_24700	0.0005115	53.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HI8V@91061|Bacilli,26W8C@186822|Paenibacillaceae	91061|Bacilli	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,SH3_3
ZZS3_k127_3834133_17	215803.DB30_1130	1.252e-43	181.0	COG1388@1|root,COG3179@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,COG3409@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2Z00D@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
ZZS3_k127_3834133_19	591159.ACEZ01000207_gene7000	7.11e-42	176.0	COG3770@1|root,COG3770@2|Bacteria,2IQ1A@201174|Actinobacteria	201174|Actinobacteria	M	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M74
ZZS3_k127_3834133_24	391625.PPSIR1_12763	8.708e-10	72.0	COG1404@1|root,COG3921@1|root,COG1404@2|Bacteria,COG3921@2|Bacteria,1PXZ6@1224|Proteobacteria,434YU@68525|delta/epsilon subdivisions,2WZ9R@28221|Deltaproteobacteria,2Z1NG@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS3_k127_3834133_11	323261.Noc_2190	7.96e-90	309.0	2C2AK@1|root,30RHD@2|Bacteria,1NSEW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_8	323261.Noc_2192	1.388e-133	439.0	28JJ9@1|root,2Z9CC@2|Bacteria,1R4HT@1224|Proteobacteria,1SKQP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_6	323261.Noc_2193	7.227e-149	501.0	29UDG@1|root,30FQ4@2|Bacteria,1NQHT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_25	1189620.AJXL01000064_gene3624	0.0002306	49.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,1HXES@117743|Flavobacteriia,2NTFP@237|Flavobacterium	976|Bacteroidetes	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_3834133_12	290397.Adeh_0922	2.935e-80	279.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_3834133_14	1379270.AUXF01000001_gene1997	1.762e-64	233.0	COG1407@1|root,COG1407@2|Bacteria,1ZU9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ICC-like phosphoesterases	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_0	357808.RoseRS_3430	0.0	1054.0	COG1201@1|root,COG1201@2|Bacteria	2|Bacteria	L	RNA secondary structure unwinding	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
ZZS3_k127_3834133_10	1123508.JH636443_gene4982	1.14e-105	349.0	COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_3834133_2	234267.Acid_3563	2.889e-225	720.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria	57723|Acidobacteria	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
ZZS3_k127_3834133_5	1379270.AUXF01000001_gene2003	5.96e-152	486.0	COG1236@1|root,COG1236@2|Bacteria,1ZTZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_3834133_16	321327.CYA_2243	1.314e-53	201.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
ZZS3_k127_3834133_21	194439.CT0296	3.459e-31	126.0	COG0730@1|root,COG0730@2|Bacteria,1FE27@1090|Chlorobi	1090|Chlorobi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ZZS3_k127_3834133_3	926550.CLDAP_36400	5.276e-219	711.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
ZZS3_k127_3913969_4	485918.Cpin_1896	1.565e-91	320.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
ZZS3_k127_3913969_0	861299.J421_4174	8.82e-213	676.0	COG1132@1|root,COG1132@2|Bacteria,1ZSP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
ZZS3_k127_3913969_3	309801.trd_A0395	1.061e-117	402.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
ZZS3_k127_3913969_1	861299.J421_4169	2.36e-126	419.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS3_k127_3913969_5	266117.Rxyl_0106	7.353e-56	205.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,4CQ2N@84995|Rubrobacteria	84995|Rubrobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
ZZS3_k127_3913969_2	1379270.AUXF01000002_gene1768	8.176e-123	406.0	COG0379@1|root,COG0379@2|Bacteria,1ZT10@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
ZZS3_k127_3913969_6	1121272.KB903261_gene6474	6.379e-46	173.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4D9BT@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS3_k127_4017640_2	264732.Moth_2312	5.985e-241	779.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,42FDP@68295|Thermoanaerobacterales	186801|Clostridia	C	Formate dehydrogenase alpha subunit	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
ZZS3_k127_4017640_12	861299.J421_2615	1.15e-26	120.0	COG4123@1|root,COG4123@2|Bacteria,1ZTJ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4017640_8	1140.Synpcc7942_1989	6.495e-53	198.0	COG0053@1|root,COG0053@2|Bacteria,1G0RT@1117|Cyanobacteria,1GYAY@1129|Synechococcus	1117|Cyanobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
ZZS3_k127_4017640_4	861299.J421_2617	5.846e-140	457.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ZZS3_k127_4017640_9	1382306.JNIM01000001_gene2653	3.666e-36	143.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
ZZS3_k127_4017640_11	983917.RGE_41690	1.374e-32	138.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,1KKTT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
ZZS3_k127_4017640_7	861299.J421_2620	7.138e-66	243.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
ZZS3_k127_4017640_10	1379270.AUXF01000004_gene3215	2.612e-33	135.0	COG0816@1|root,COG0816@2|Bacteria,1ZTWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
ZZS3_k127_4017640_3	1379698.RBG1_1C00001G0312	2.083e-190	603.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
ZZS3_k127_4017640_6	379066.GAU_2430	4.128e-102	346.0	COG3437@1|root,COG3437@2|Bacteria,1ZSX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
ZZS3_k127_4017640_0	1232410.KI421418_gene2249	0.0	1339.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,43T2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ZZS3_k127_4017640_13	1296416.JACB01000006_gene395	3.495e-18	89.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1I44S@117743|Flavobacteriia,2YK14@290174|Aquimarina	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_4017640_5	404380.Gbem_2406	1.256e-139	474.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
ZZS3_k127_4017640_1	378806.STAUR_7575	0.0	1106.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2Z3GS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
ZZS3_k127_4186462_14	446465.Bfae_03760	3.987e-78	274.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4FC41@85020|Dermabacteraceae	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
ZZS3_k127_4186462_27	575615.HMPREF0670_01886	1.752e-16	85.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,2G0S4@200643|Bacteroidia	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_4186462_13	861299.J421_4163	7.353e-82	291.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS3_k127_4186462_12	379066.GAU_2572	5.244e-84	297.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
ZZS3_k127_4186462_0	1379270.AUXF01000001_gene2822	3.243e-310	1024.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
ZZS3_k127_4186462_15	1379698.RBG1_1C00001G0436	3.162e-63	228.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS3_k127_4186462_28	861299.J421_4159	1.548e-12	76.0	COG1555@1|root,COG1555@2|Bacteria,1ZV96@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
ZZS3_k127_4186462_29	867903.ThesuDRAFT_00669	2.344e-11	73.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WDDX@538999|Clostridiales incertae sedis	186801|Clostridia	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
ZZS3_k127_4186462_6	639282.DEFDS_1109	1.701e-194	622.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
ZZS3_k127_4186462_7	379066.GAU_2569	5.338e-188	595.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS3_k127_4186462_9	861299.J421_4156	3.581e-165	528.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
ZZS3_k127_4186462_24	404589.Anae109_4072	1.766e-29	128.0	293J8@1|root,2ZR19@2|Bacteria,1R6Y4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4186462_22	1173026.Glo7428_3455	3.941e-33	133.0	COG1846@1|root,COG1846@2|Bacteria,1G6FP@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
ZZS3_k127_4186462_2	1500893.JQNB01000001_gene2681	1.665e-237	745.0	COG1028@1|root,COG1028@2|Bacteria,1R4BM@1224|Proteobacteria,1SE2R@1236|Gammaproteobacteria,1X5FD@135614|Xanthomonadales	135614|Xanthomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS3_k127_4186462_1	1040987.AZUY01000037_gene2235	2.467e-258	810.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
ZZS3_k127_4186462_23	265072.Mfla_1450	4.738e-31	131.0	COG2010@1|root,COG2010@2|Bacteria,1RHET@1224|Proteobacteria,2W3EV@28216|Betaproteobacteria,2KP1A@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_4186462_16	1236959.BAMT01000014_gene2886	4.132e-61	225.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VQ5E@28216|Betaproteobacteria,2KP6C@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
ZZS3_k127_4186462_3	365046.Rta_06250	5.163e-230	743.0	COG0843@1|root,COG1845@1|root,COG0843@2|Bacteria,COG1845@2|Bacteria,1MU7S@1224|Proteobacteria,2VM0G@28216|Betaproteobacteria,4ABUI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298,ko:K15408	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
ZZS3_k127_4186462_32	639283.Snov_1017	0.0009052	47.0	2E5ZP@1|root,330P3@2|Bacteria,1MZC5@1224|Proteobacteria,2UBWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4186462_19	1121943.KB900010_gene2737	2.705e-36	141.0	COG2010@1|root,COG2010@2|Bacteria,1QVIB@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
ZZS3_k127_4186462_31	234267.Acid_0704	1.965e-06	59.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS3_k127_4186462_20	1379270.AUXF01000001_gene2224	1.554e-35	139.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS3_k127_4186462_8	404589.Anae109_1775	4.715e-178	578.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,42ZD0@68525|delta/epsilon subdivisions,2WU4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
ZZS3_k127_4186462_4	518766.Rmar_1401	1.514e-198	627.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1FJ4C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS3_k127_4186462_21	1379270.AUXF01000003_gene3372	9.536e-35	136.0	COG1188@1|root,COG1188@2|Bacteria,1ZTXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
ZZS3_k127_4186462_18	479434.Sthe_0894	2.684e-41	175.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
ZZS3_k127_4186462_10	1123508.JH636446_gene6369	1.375e-118	413.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_4186462_17	1121926.AXWO01000019_gene1914	2.825e-52	192.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
ZZS3_k127_4186462_25	404589.Anae109_2891	3.08e-24	104.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42V9P@68525|delta/epsilon subdivisions,2X5QW@28221|Deltaproteobacteria,2Z1ZE@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
ZZS3_k127_4186462_11	379066.GAU_2526	7.815e-116	395.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
ZZS3_k127_4186462_5	861299.J421_3987	5.829e-197	624.0	COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_4186462_30	861299.J421_3986	9.429e-07	53.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilE	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl
ZZS3_k127_4239957_1	379066.GAU_0793	7.332e-178	565.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
ZZS3_k127_4239957_2	1239962.C943_03877	3.523e-22	111.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
ZZS3_k127_4239957_0	868595.Desca_0006	7.615e-233	732.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
ZZS3_k127_424565_10	402777.KB235903_gene2226	7.612e-37	143.0	2EDZR@1|root,337UJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_424565_9	234267.Acid_7379	1.037e-38	164.0	2A08G@1|root,33ENC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_424565_11	867845.KI911784_gene617	8.518e-35	148.0	COG1216@1|root,COG1216@2|Bacteria,2GAH6@200795|Chloroflexi,377WE@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
ZZS3_k127_424565_7	1396141.BATP01000039_gene1244	3.405e-44	171.0	COG0500@1|root,COG0726@1|root,COG1215@1|root,COG0500@2|Bacteria,COG0726@2|Bacteria,COG1215@2|Bacteria,46WUT@74201|Verrucomicrobia,2IWQ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_424565_0	251229.Chro_2374	1.202e-165	540.0	COG1216@1|root,COG1216@2|Bacteria,1GQEZ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2
ZZS3_k127_424565_6	983917.RGE_10770	6.304e-59	220.0	COG0438@1|root,COG0438@2|Bacteria,1RF47@1224|Proteobacteria,2VZMK@28216|Betaproteobacteria,1KNCA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
ZZS3_k127_424565_8	696281.Desru_1554	2.722e-41	166.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_424565_14	319795.Dgeo_2504	6.289e-08	65.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	APH,Choline_kinase
ZZS3_k127_424565_1	221288.JH992901_gene4137	9.021e-138	449.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1JJE1@1189|Stigonemataceae	1117|Cyanobacteria	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
ZZS3_k127_424565_2	234267.Acid_4640	1.198e-95	325.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
ZZS3_k127_424565_12	526225.Gobs_0233	1.099e-22	114.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ZZS3_k127_424565_3	326424.FRAAL5056	1.605e-89	313.0	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4ESEF@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_424565_13	1089550.ATTH01000001_gene889	2.062e-21	106.0	COG1216@1|root,COG1216@2|Bacteria,4PND5@976|Bacteroidetes,1FKBH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_424565_5	1335760.ASTG01000016_gene104	2.482e-59	222.0	COG0438@1|root,COG0438@2|Bacteria,1RBYC@1224|Proteobacteria,2U6QI@28211|Alphaproteobacteria,2K978@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_424565_4	861299.J421_2443	2.745e-89	301.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
ZZS3_k127_4274601_11	379066.GAU_1731	3.749e-128	419.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
ZZS3_k127_4274601_14	379066.GAU_1730	4.427e-116	390.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_4274601_24	379066.GAU_1729	6.683e-72	252.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
ZZS3_k127_4274601_18	1379270.AUXF01000006_gene163	1.559e-100	339.0	COG0547@1|root,COG0547@2|Bacteria,1ZTDS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
ZZS3_k127_4274601_21	379066.GAU_1726	1.273e-77	265.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
ZZS3_k127_4274601_28	222534.KB893671_gene3315	3.681e-52	194.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4ERMN@85013|Frankiales	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
ZZS3_k127_4274601_40	760568.Desku_1853	5.966e-32	132.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
ZZS3_k127_4274601_4	379066.GAU_1723	3.177e-183	580.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_4274601_16	379066.GAU_1722	9.404e-107	366.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS3_k127_4274601_9	379066.GAU_1721	4.602e-137	451.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
ZZS3_k127_4274601_23	379066.GAU_1720	6.471e-72	251.0	COG0159@1|root,COG0159@2|Bacteria,1ZSYU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
ZZS3_k127_4274601_43	243231.GSU2942	3.626e-23	116.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Chemotaxis sensory transducer	mcp40H-19	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
ZZS3_k127_4274601_33	861299.J421_3360	1.007e-41	159.0	COG0801@1|root,COG1713@1|root,COG0801@2|Bacteria,COG1713@2|Bacteria,1ZTTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
ZZS3_k127_4274601_19	1121423.JONT01000026_gene890	3.086e-94	316.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
ZZS3_k127_4274601_20	479434.Sthe_0699	3.805e-84	287.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
ZZS3_k127_4274601_32	720554.Clocl_2124	9.53e-42	158.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,3WJM9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
ZZS3_k127_4274601_39	1379270.AUXF01000006_gene171	4.527e-32	136.0	COG1713@1|root,COG1713@2|Bacteria,1ZTTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
ZZS3_k127_4274601_45	665571.STHERM_c10310	4.026e-11	70.0	COG1316@1|root,COG1316@2|Bacteria,2J57I@203691|Spirochaetes	203691|Spirochaetes	K	PFAM Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
ZZS3_k127_4274601_17	861299.J421_4234	2.303e-105	359.0	COG2379@1|root,COG2379@2|Bacteria,1ZTSG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
ZZS3_k127_4274601_3	460265.Mnod_7112	5.252e-185	588.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,1JTFN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM aminotransferase class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ZZS3_k127_4274601_8	1408224.SAMCCGM7_c3346	1.086e-143	462.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,4BCRG@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
ZZS3_k127_4274601_5	1000565.METUNv1_00583	8.888e-183	579.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KV9X@206389|Rhodocyclales	28216|Betaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
ZZS3_k127_4274601_6	159450.NH14_09545	2.641e-150	483.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1K1FH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5,6.2.1.9	ko:K01902,ko:K08692	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
ZZS3_k127_4274601_13	243233.MCA1407	4.168e-117	397.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RMGZ@1236|Gammaproteobacteria,1XEC8@135618|Methylococcales	135618|Methylococcales	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ZZS3_k127_4274601_0	663610.JQKO01000011_gene3313	0.0	1141.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2TR6F@28211|Alphaproteobacteria,3NC0Z@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Phosphoenolpyruvate carboxylase	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
ZZS3_k127_4274601_12	861299.J421_3358	2.151e-122	402.0	COG0820@1|root,COG0820@2|Bacteria,1ZTAJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
ZZS3_k127_4274601_42	1265505.ATUG01000003_gene169	8.748e-26	112.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2MKBM@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
ZZS3_k127_4274601_1	379066.GAU_1715	3.173e-240	756.0	COG0173@1|root,COG0173@2|Bacteria,1ZTFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
ZZS3_k127_4274601_10	1379270.AUXF01000006_gene175	1.016e-129	421.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
ZZS3_k127_4274601_7	861299.J421_3354	3.548e-148	497.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
ZZS3_k127_4274601_38	379066.GAU_1713	1.702e-34	136.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
ZZS3_k127_4274601_29	926550.CLDAP_13200	1.576e-45	183.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
ZZS3_k127_4274601_35	1521187.JPIM01000011_gene2663	4.715e-41	169.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,3752J@32061|Chloroflexia	32061|Chloroflexia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
ZZS3_k127_4274601_15	1270196.JCKI01000004_gene882	1.099e-114	385.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
ZZS3_k127_4274601_2	861299.J421_1944	2.443e-212	673.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
ZZS3_k127_4274601_26	1267533.KB906736_gene1216	1.496e-55	197.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_4274601_41	204669.Acid345_2044	1.537e-28	119.0	COG0662@1|root,COG0662@2|Bacteria,3Y8RS@57723|Acidobacteria,2JNY9@204432|Acidobacteriia	204432|Acidobacteriia	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_4274601_25	1121957.ATVL01000007_gene2363	1.86e-67	251.0	COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,47KWV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
ZZS3_k127_4274601_34	1341181.FLJC2902T_14440	1.096e-41	157.0	COG3631@1|root,COG3631@2|Bacteria,4NTMZ@976|Bacteroidetes,1I61G@117743|Flavobacteriia,2NWYB@237|Flavobacterium	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
ZZS3_k127_4274601_31	1250005.PHEL85_2495	1.049e-42	168.0	COG4642@1|root,COG4642@2|Bacteria,4PKDJ@976|Bacteroidetes,1IJ8B@117743|Flavobacteriia	976|Bacteroidetes	S	MORN repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4274601_27	105422.BBPM01000048_gene1641	3.207e-53	190.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,2NIXH@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
ZZS3_k127_4274601_22	1266925.JHVX01000007_gene2418	2.496e-76	259.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VRJ0@28216|Betaproteobacteria,374MK@32003|Nitrosomonadales	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
ZZS3_k127_4274601_44	1396141.BATP01000018_gene1537	2.699e-21	100.0	2FI25@1|root,349V0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4274601_30	861299.J421_1503	1.611e-45	175.0	COG2318@1|root,COG2318@2|Bacteria,1ZU0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_4274601_36	1410620.SHLA_129c000050	3.371e-40	156.0	COG0640@1|root,COG0640@2|Bacteria,1RCIH@1224|Proteobacteria,2U6EZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_4274601_46	1379698.RBG1_1C00001G0757	1.313e-10	72.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
ZZS3_k127_4306978_6	269799.Gmet_1782	3.06e-102	338.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
ZZS3_k127_4306978_3	1379270.AUXF01000001_gene2086	2.085e-122	413.0	COG2274@1|root,COG2274@2|Bacteria,1ZSX6@142182|Gemmatimonadetes	2|Bacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
ZZS3_k127_4306978_24	32057.KB217478_gene1419	1.765e-07	61.0	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
ZZS3_k127_4306978_22	272134.KB731324_gene3070	6.648e-09	65.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HA4H@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
ZZS3_k127_4306978_14	392499.Swit_4548	2.361e-33	148.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2K6H5@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ZZS3_k127_4306978_9	1123242.JH636434_gene5497	2.952e-64	245.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS3_k127_4306978_12	861299.J421_1799	4.787e-46	191.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1ZT79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
ZZS3_k127_4306978_10	861299.J421_2385	1.19e-53	203.0	COG3712@1|root,COG3712@2|Bacteria,1ZV31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
ZZS3_k127_4306978_20	1408813.AYMG01000029_gene4714	2.72e-13	78.0	COG1595@1|root,COG1595@2|Bacteria,4NTI5@976|Bacteroidetes	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_4306978_19	379066.GAU_0393	2.225e-13	74.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
ZZS3_k127_4306978_21	880073.Calab_3325	1.377e-09	66.0	28ZRK@1|root,2ZMGF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4306978_5	1123377.AUIV01000003_gene1811	1.555e-112	376.0	COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,1RP0S@1236|Gammaproteobacteria,1X34Z@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	-	-	-	-	-	-	-	-	-	Glt_symporter
ZZS3_k127_4306978_23	1120951.AUBG01000010_gene1979	1.153e-08	59.0	2DMPS@1|root,32SXU@2|Bacteria,4NTIT@976|Bacteroidetes,1I41A@117743|Flavobacteriia	976|Bacteroidetes	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_4306978_0	1379698.RBG1_1C00001G0830	3.35e-198	638.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ZZS3_k127_4306978_17	502025.Hoch_4464	3.096e-30	122.0	COG1977@1|root,COG1977@2|Bacteria,1N4M4@1224|Proteobacteria,43BB7@68525|delta/epsilon subdivisions,2X6QD@28221|Deltaproteobacteria,2Z3C9@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
ZZS3_k127_4306978_1	502025.Hoch_4465	2.725e-153	492.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,432XE@68525|delta/epsilon subdivisions,2WYHS@28221|Deltaproteobacteria,2YU0E@29|Myxococcales	28221|Deltaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4306978_13	1366050.N234_20075	1.203e-43	163.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,1KDIQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
ZZS3_k127_4306978_26	1185876.BN8_06492	2.449e-06	57.0	COG5492@1|root,COG5492@2|Bacteria,4PPFX@976|Bacteroidetes,47YMG@768503|Cytophagia	976|Bacteroidetes	N	ZU5 domain	-	-	-	-	-	-	-	-	-	-	-	-	ZU5
ZZS3_k127_4306978_7	861299.J421_3723	8.238e-97	337.0	COG0457@1|root,COG2206@1|root,COG0457@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE6_C,DICT,GerE,HD,HD_5
ZZS3_k127_4306978_25	1068978.AMETH_5965	1.132e-06	60.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,Trans_reg_C
ZZS3_k127_4306978_4	861299.J421_0829	2.821e-117	392.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GAF,HTH_8,Sigma54_activat
ZZS3_k127_4306978_16	309807.SRU_1452	2.515e-31	133.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4306978_2	945713.IALB_3087	5.586e-131	429.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
ZZS3_k127_4306978_18	530564.Psta_3376	1.485e-27	128.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS3_k127_4306978_11	1191523.MROS_1828	4.495e-53	202.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS3_k127_4306978_8	1232410.KI421421_gene3684	1.294e-95	325.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,43UHD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS3_k127_4328652_5	404589.Anae109_1015	8.522e-154	493.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
ZZS3_k127_4328652_32	1449069.JMLO01000018_gene588	2.024e-06	59.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
ZZS3_k127_4328652_28	926560.KE387023_gene3760	2.46e-22	103.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Malectin
ZZS3_k127_4328652_20	886293.Sinac_3762	2.098e-56	208.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,2IZ1I@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
ZZS3_k127_4328652_19	861299.J421_1819	5.392e-72	258.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368,ko:K02638	ko00195,ko00910,ko01120,map00195,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Copper-bind,Cupredoxin_1
ZZS3_k127_4328652_30	485913.Krac_8476	2.02e-16	83.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
ZZS3_k127_4328652_21	861299.J421_4239	1.154e-48	182.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
ZZS3_k127_4328652_3	861299.J421_1971	2.163e-164	534.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
ZZS3_k127_4328652_16	1123248.KB893337_gene2570	1.972e-79	273.0	COG2146@1|root,COG4244@1|root,COG2146@2|Bacteria,COG4244@2|Bacteria,4NPHV@976|Bacteroidetes	976|Bacteroidetes	P	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
ZZS3_k127_4328652_31	1211114.ALIP01000056_gene2726	1.158e-14	77.0	2EKH8@1|root,33E79@2|Bacteria,1QBBW@1224|Proteobacteria,1T6WM@1236|Gammaproteobacteria,1X8B9@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4328652_17	861299.J421_0557	2.402e-77	269.0	2DBB1@1|root,2Z854@2|Bacteria	2|Bacteria	S	membrane	yxxB	-	-	-	-	-	-	-	-	-	-	-	DUF1206
ZZS3_k127_4328652_6	1379270.AUXF01000006_gene133	4.918e-151	486.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ZZS3_k127_4328652_18	886293.Sinac_3650	4.48e-76	264.0	COG2318@1|root,COG2318@2|Bacteria,2IZ34@203682|Planctomycetes	203682|Planctomycetes	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
ZZS3_k127_4328652_14	1382304.JNIL01000001_gene3207	2.218e-99	329.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
ZZS3_k127_4328652_9	1379270.AUXF01000003_gene3840	1.359e-118	398.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1ZTDZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
ZZS3_k127_4328652_11	861299.J421_3620	1.606e-100	335.0	COG0745@1|root,COG0745@2|Bacteria,1ZT8B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_4328652_10	861299.J421_3619	5.449e-110	372.0	COG5002@1|root,COG5002@2|Bacteria,1ZTF2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ZZS3_k127_4328652_22	861299.J421_3618	5.294e-47	178.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
ZZS3_k127_4328652_12	861299.J421_3617	1.617e-100	333.0	COG0811@1|root,COG0811@2|Bacteria,1ZTH1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
ZZS3_k127_4328652_24	861299.J421_3616	2.223e-38	148.0	COG0848@1|root,COG0848@2|Bacteria,1ZTTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
ZZS3_k127_4328652_26	379066.GAU_2008	5.457e-32	132.0	COG0848@1|root,COG0848@2|Bacteria,1ZTXP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
ZZS3_k127_4328652_4	575540.Isop_3575	6.753e-154	501.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS3_k127_4328652_27	570268.ANBB01000047_gene3971	3.444e-24	119.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria,4EJEV@85012|Streptosporangiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
ZZS3_k127_4328652_8	1379270.AUXF01000003_gene3853	2.35e-125	419.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
ZZS3_k127_4328652_23	1379270.AUXF01000003_gene3855	5.366e-42	158.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
ZZS3_k127_4328652_2	251221.35214024	1.633e-210	671.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
ZZS3_k127_4328652_15	1379270.AUXF01000003_gene3856	2.209e-81	290.0	COG1680@1|root,COG1680@2|Bacteria,1ZT58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_4328652_7	861299.J421_3604	7.33e-131	437.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
ZZS3_k127_4328652_13	1382356.JQMP01000003_gene1834	3.974e-100	340.0	COG3876@1|root,COG3876@2|Bacteria,2G655@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
ZZS3_k127_4328652_25	861299.J421_3602	2.389e-35	144.0	COG0558@1|root,COG0558@2|Bacteria,1ZTIP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ZZS3_k127_4328652_1	1121272.KB903250_gene2734	1.542e-214	678.0	COG1260@1|root,COG1260@2|Bacteria,2GJVN@201174|Actinobacteria	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
ZZS3_k127_4328652_29	861299.J421_3599	2.539e-20	93.0	2FD8C@1|root,345AC@2|Bacteria,1ZTXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4328652_0	1267535.KB906767_gene2605	0.0	1049.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
ZZS3_k127_4337795_4	1502850.FG91_04084	1.161e-28	116.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,2K4WC@204457|Sphingomonadales	204457|Sphingomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
ZZS3_k127_4337795_0	322710.Avin_20870	1.628e-159	519.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
ZZS3_k127_4337795_8	187303.BN69_0140	5.188e-07	54.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2U247@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_4337795_1	909663.KI867150_gene69	6.734e-59	213.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4337795_3	379066.GAU_1387	2.497e-53	205.0	COG3278@1|root,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4337795_5	937777.Deipe_0657	1.426e-24	108.0	2E8I5@1|root,332W5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4337795_7	948106.AWZT01000006_gene3158	1.355e-07	62.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,2VSSM@28216|Betaproteobacteria,1K2HQ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
ZZS3_k127_4337795_6	1382356.JQMP01000003_gene2516	2.045e-23	108.0	COG1595@1|root,COG1595@2|Bacteria,2G90X@200795|Chloroflexi,27Z65@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_4337795_2	1379698.RBG1_1C00001G0607	1.385e-54	203.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
ZZS3_k127_4404766_2	316067.Geob_2004	4.483e-55	208.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,42VG3@68525|delta/epsilon subdivisions,2WRB7@28221|Deltaproteobacteria,43VHN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4404766_1	861299.J421_3956	3.289e-58	206.0	COG0521@1|root,COG0521@2|Bacteria,1ZU2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
ZZS3_k127_4404766_0	861299.J421_6329	2.539e-85	297.0	COG1470@1|root,COG5184@1|root,COG1470@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	F5_F8_type_C,Flg_new,RCC1,RCC1_2
ZZS3_k127_4404766_3	1121013.P873_11380	3.593e-34	136.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1X6CE@135614|Xanthomonadales	135614|Xanthomonadales	J	endoribonuclease	yjgF	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
ZZS3_k127_4486041_13	114615.BRADO0005	7.39e-68	235.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,3JVEC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
ZZS3_k127_4486041_7	861299.J421_3181	9.181e-102	342.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
ZZS3_k127_4486041_19	379066.GAU_0945	6.61e-58	216.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
ZZS3_k127_4486041_5	1249627.D779_0071	4.13e-144	477.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
ZZS3_k127_4486041_2	861299.J421_3179	1.356e-156	508.0	COG0154@1|root,COG0154@2|Bacteria,1ZT24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ZZS3_k127_4486041_28	278197.PEPE_1370	3.302e-06	53.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
ZZS3_k127_4486041_1	861299.J421_3177	1.514e-221	712.0	COG0210@1|root,COG0210@2|Bacteria,1ZTD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ZZS3_k127_4486041_11	1379270.AUXF01000005_gene810	2.37e-80	281.0	COG5000@1|root,COG5000@2|Bacteria,1ZSKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ZZS3_k127_4486041_4	861299.J421_3175	1.754e-144	470.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
ZZS3_k127_4486041_25	379066.GAU_1542	5.02e-17	88.0	2FES0@1|root,346R1@2|Bacteria,1ZU3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4486041_29	390989.JOEG01000011_gene274	7.689e-06	53.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria,4DD3M@85008|Micromonosporales	201174|Actinobacteria	S	Roadblock lc7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
ZZS3_k127_4486041_9	1379270.AUXF01000005_gene805	2.949e-95	324.0	COG0836@1|root,COG0836@2|Bacteria,1ZT5Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS3_k127_4486041_15	1379270.AUXF01000005_gene804	4.205e-65	239.0	COG1208@1|root,COG1208@2|Bacteria,1ZSVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
ZZS3_k127_4486041_21	644282.Deba_0900	2.426e-46	180.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
ZZS3_k127_4486041_26	379066.GAU_1167	9.097e-16	85.0	2FCTB@1|root,344W9@2|Bacteria,1ZU4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4486041_17	1121377.KB906403_gene3108	1.3e-62	225.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS3_k127_4486041_0	861299.J421_3164	4.474e-286	885.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
ZZS3_k127_4486041_23	379066.GAU_1535	2.061e-33	132.0	COG0234@1|root,COG0234@2|Bacteria,1ZTZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
ZZS3_k127_4486041_27	1123368.AUIS01000024_gene944	1.858e-15	86.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,1S884@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
ZZS3_k127_4486041_30	1120936.KB907208_gene1207	8.08e-05	55.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4486041_24	742159.HMPREF0004_3597	1.721e-23	113.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,3T5FG@506|Alcaligenaceae	28216|Betaproteobacteria	M	NlpC P60 family protein	-	-	-	ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
ZZS3_k127_4486041_12	903818.KI912268_gene1569	1.491e-74	263.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.133,2.5.1.62	ko:K04040,ko:K20616	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
ZZS3_k127_4486041_16	604331.AUHY01000011_gene222	7.434e-63	226.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
ZZS3_k127_4486041_20	379066.GAU_1534	1.745e-48	188.0	COG0340@1|root,COG0340@2|Bacteria,1ZTQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
ZZS3_k127_4486041_10	1121035.AUCH01000006_gene765	1.893e-85	290.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
ZZS3_k127_4486041_6	379066.GAU_1532	5.801e-133	433.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1ZT2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_4486041_14	861299.J421_3156	1.782e-65	237.0	COG0324@1|root,COG0324@2|Bacteria,1ZTBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
ZZS3_k127_4486041_3	861299.J421_3155	3.691e-154	505.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ZZS3_k127_4486041_22	1379270.AUXF01000005_gene783	4.559e-44	184.0	COG4783@1|root,COG4783@2|Bacteria,1ZT36@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD,SH3_4
ZZS3_k127_4486041_18	861299.J421_3153	6.59e-62	237.0	COG2304@1|root,COG2304@2|Bacteria,1ZTCZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
ZZS3_k127_4486041_8	379066.GAU_1527	3.014e-100	338.0	COG2304@1|root,COG2304@2|Bacteria,1ZSVY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1194)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
ZZS3_k127_4500746_1	861299.J421_2090	1.494e-257	802.0	COG0719@1|root,COG0719@2|Bacteria,1ZSMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
ZZS3_k127_4500746_8	379066.GAU_3026	2.569e-37	156.0	COG2345@1|root,COG2345@2|Bacteria,1ZTKU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_4500746_9	1395513.P343_17755	1.123e-34	145.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HHMA@91061|Bacilli	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ZZS3_k127_4500746_3	379066.GAU_0096	1.34e-110	383.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
ZZS3_k127_4500746_7	1379270.AUXF01000001_gene2401	3.358e-45	164.0	COG1146@1|root,COG1146@2|Bacteria,1ZU19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
ZZS3_k127_4500746_6	330214.NIDE3554	1.268e-58	220.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
ZZS3_k127_4500746_11	861299.J421_2107	5.052e-20	104.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ysmA	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2
ZZS3_k127_4500746_2	861299.J421_2109	5.195e-111	370.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
ZZS3_k127_4500746_10	1150474.JQJI01000002_gene1102	3.249e-28	116.0	COG2151@1|root,COG2151@2|Bacteria,2GDA3@200918|Thermotogae	200918|Thermotogae	S	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
ZZS3_k127_4500746_4	861299.J421_2113	5.006e-79	278.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ZZS3_k127_4500746_13	269797.Mbar_A3214	3.759e-08	64.0	COG5549@1|root,arCOG04994@2157|Archaea	2157|Archaea	O	Peptidase M10A and M12B matrixin and adamalysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
ZZS3_k127_4500746_0	861299.J421_1151	4.979e-311	987.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
ZZS3_k127_4500746_5	379066.GAU_0009	2.372e-68	250.0	2DTII@1|root,33KI8@2|Bacteria,1ZT3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4500746_12	379066.GAU_0008	9.855e-10	60.0	COG0515@1|root,COG0515@2|Bacteria,1ZT9E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_4539731_20	266117.Rxyl_1978	9.691e-70	248.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4CQ8E@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
ZZS3_k127_4539731_14	1089550.ATTH01000001_gene258	8.921e-116	389.0	COG1232@1|root,COG1232@2|Bacteria,4NH1E@976|Bacteroidetes,1FIR6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
ZZS3_k127_4539731_10	357808.RoseRS_1753	4.036e-161	520.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,374V4@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_4539731_13	926560.KE387027_gene562	9.864e-126	411.0	COG0113@1|root,COG0113@2|Bacteria,1WINH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
ZZS3_k127_4539731_28	1122137.AQXF01000002_gene649	2.426e-45	182.0	COG1228@1|root,COG1228@2|Bacteria,1R86X@1224|Proteobacteria,2U400@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_4539731_26	1382306.JNIM01000001_gene3473	5.665e-46	183.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
ZZS3_k127_4539731_29	395495.Lcho_3770	4.116e-39	158.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria,1KMQI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_4539731_37	156889.Mmc1_3715	2.561e-22	100.0	COG2033@1|root,COG2033@2|Bacteria,1QVWP@1224|Proteobacteria,2TWVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
ZZS3_k127_4539731_36	1123368.AUIS01000007_gene2801	9.056e-23	104.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S4ZT@1236|Gammaproteobacteria,2NCUM@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,TAT_signal
ZZS3_k127_4539731_30	660470.Theba_0228	1.522e-35	156.0	COG4412@1|root,COG4412@2|Bacteria,2GDTB@200918|Thermotogae	200918|Thermotogae	M	TIGRFAM M6 family metalloprotease domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
ZZS3_k127_4539731_11	861299.J421_0795	5.385e-150	492.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	2|Bacteria	H	Beta-eliminating lyase	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ZZS3_k127_4539731_16	1144275.COCOR_04256	3.764e-106	363.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4539731_23	448385.sce7198	9.562e-54	207.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ZZS3_k127_4539731_33	861299.J421_0797	4.727e-32	138.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	dgkA	-	2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K00901,ko:K01096,ko:K19302	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02029,R02240,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2,PAP2_3
ZZS3_k127_4539731_35	1379270.AUXF01000002_gene1410	1.95e-25	115.0	COG3794@1|root,COG3794@2|Bacteria,1ZTTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
ZZS3_k127_4539731_31	861299.J421_0442	5.507e-35	139.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_4539731_22	861299.J421_3626	1.036e-54	213.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4539731_39	1379270.AUXF01000003_gene3825	1.559e-17	92.0	COG2010@1|root,COG2010@2|Bacteria,1ZTPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_4539731_34	1379270.AUXF01000003_gene3824	1.243e-29	127.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
ZZS3_k127_4539731_8	1379270.AUXF01000003_gene3823	2.684e-167	537.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
ZZS3_k127_4539731_2	861299.J421_3630	4.574e-250	806.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
ZZS3_k127_4539731_32	1232410.KI421425_gene1566	3.417e-33	135.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4539731_27	1379270.AUXF01000003_gene3817	1.465e-45	184.0	COG0565@1|root,COG0565@2|Bacteria,1ZT19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	SpoU rRNA Methylase family	-	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
ZZS3_k127_4539731_7	861299.J421_3743	9.708e-178	569.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS3_k127_4539731_17	379066.GAU_2702	2.785e-92	314.0	COG2084@1|root,COG2084@2|Bacteria,1ZT54@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
ZZS3_k127_4539731_25	1123371.ATXH01000008_gene246	1.815e-48	179.0	COG1528@1|root,COG1528@2|Bacteria,2GGRA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
ZZS3_k127_4539731_21	861299.J421_2076	2.657e-69	244.0	COG0555@1|root,COG0555@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	wtpB	-	-	ko:K15496	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	BPD_transp_1
ZZS3_k127_4539731_18	574087.Acear_1347	4.78e-83	287.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WABU@53433|Halanaerobiales	186801|Clostridia	P	ABC transporter	wtpC	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K15497	ko02010,map02010	M00189,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5,3.A.1.8	-	-	ABC_tran,TOBE,TOBE_2
ZZS3_k127_4539731_19	234267.Acid_0850	9.338e-73	267.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria	57723|Acidobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
ZZS3_k127_4539731_3	357808.RoseRS_2983	1.209e-222	699.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi,376YP@32061|Chloroflexia	32061|Chloroflexia	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
ZZS3_k127_4539731_6	262724.TT_C1950	7.869e-192	607.0	COG0004@1|root,COG0004@2|Bacteria,1WIFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
ZZS3_k127_4539731_24	300852.55771439	4.171e-52	186.0	COG0347@1|root,COG0347@2|Bacteria,1WJZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
ZZS3_k127_4539731_1	1173027.Mic7113_3436	5.952e-288	892.0	COG0129@1|root,COG0129@2|Bacteria,1G0KD@1117|Cyanobacteria,1H8V6@1150|Oscillatoriales	1117|Cyanobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ZZS3_k127_4539731_15	309807.SRU_2148	1.8e-108	365.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1FJU9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS3_k127_4539731_4	292459.STH2116	1.328e-216	682.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
ZZS3_k127_4539731_12	671143.DAMO_1363	5.572e-139	453.0	COG0059@1|root,COG0059@2|Bacteria,2NNKS@2323|unclassified Bacteria	2|Bacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iHN637.CLJU_RS07505,iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iIT341.HP0330,iJN746.PP_4678,iLF82_1304.LF82_1103,iLJ478.TM0550	IlvC,IlvN
ZZS3_k127_4539731_38	378753.KRH_10220	3.933e-18	98.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,1W8PT@1268|Micrococcaceae	201174|Actinobacteria	E	Acetolactate synthase, small subunit	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
ZZS3_k127_4539731_5	1382306.JNIM01000001_gene1241	1.804e-208	665.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi	200795|Chloroflexi	H	Thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ZZS3_k127_4539731_9	1121920.AUAU01000037_gene2735	2.543e-161	524.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
ZZS3_k127_4539731_0	309801.trd_1105	0.0	1526.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,27Z18@189775|Thermomicrobia	189775|Thermomicrobia	E	GXGXG motif	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
ZZS3_k127_4638250_2	1242864.D187_000036	1.54e-67	258.0	COG2267@1|root,COG2267@2|Bacteria,1R08U@1224|Proteobacteria,42XGE@68525|delta/epsilon subdivisions,2X8N8@28221|Deltaproteobacteria,2Z36G@29|Myxococcales	28221|Deltaproteobacteria	I	Pfam:DUF2305	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
ZZS3_k127_4638250_0	211165.AJLN01000100_gene4246	1.707e-155	520.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
ZZS3_k127_4638250_1	1380390.JIAT01000009_gene1598	1.2e-109	375.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4CTX9@84995|Rubrobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
ZZS3_k127_4638250_3	1394178.AWOO02000001_gene1210	6.837e-50	178.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4EGIG@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
ZZS3_k127_4644303_3	1042326.AZNV01000003_gene3997	2.715e-77	259.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,4B8Q9@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
ZZS3_k127_4644303_2	266835.14021842	2.599e-86	293.0	COG2844@1|root,COG2844@2|Bacteria,1QY64@1224|Proteobacteria,2TXHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
ZZS3_k127_4644303_0	1089545.KB913037_gene1597	0.0	1116.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4EE2H@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
ZZS3_k127_4644303_5	379066.GAU_3022	5.848e-40	151.0	COG1146@1|root,COG1146@2|Bacteria,1ZU19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
ZZS3_k127_4644303_6	351607.Acel_1033	9.226e-37	143.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
ZZS3_k127_4644303_7	390874.Tpet_0887	3.132e-30	128.0	COG1618@1|root,COG1618@2|Bacteria,2GEFD@200918|Thermotogae	200918|Thermotogae	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
ZZS3_k127_4644303_1	1385517.N800_11360	3.412e-139	452.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,1RSI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
ZZS3_k127_4644303_4	749222.Nitsa_0770	1.415e-47	180.0	COG1225@1|root,COG1225@2|Bacteria,1NZF4@1224|Proteobacteria,42ZRX@68525|delta/epsilon subdivisions,2YRRA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4683595_15	1192034.CAP_7436	1.432e-25	114.0	COG1670@1|root,COG1670@2|Bacteria,1NG0Z@1224|Proteobacteria	1224|Proteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ZZS3_k127_4683595_3	1382356.JQMP01000001_gene812	4.57e-106	355.0	COG1294@1|root,COG1294@2|Bacteria,2G6IA@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
ZZS3_k127_4683595_1	1382356.JQMP01000001_gene813	2.601e-166	540.0	COG1271@1|root,COG1271@2|Bacteria,2G63Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
ZZS3_k127_4683595_11	204669.Acid345_0808	1.511e-36	156.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_0808|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4683595_9	861299.J421_0777	3.313e-49	181.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
ZZS3_k127_4683595_2	323261.Noc_0468	6.421e-139	456.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,1WXGY@135613|Chromatiales	135613|Chromatiales	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
ZZS3_k127_4683595_13	349124.Hhal_0546	3.004e-28	115.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavin and coenzyme A sequestration protein dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
ZZS3_k127_4683595_6	886293.Sinac_4049	6.025e-64	225.0	COG0783@1|root,COG0783@2|Bacteria,2IZJP@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
ZZS3_k127_4683595_4	391625.PPSIR1_35832	1.785e-96	349.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_4683595_0	1123368.AUIS01000044_gene15	4.209e-184	585.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_4683595_12	1120973.AQXL01000126_gene2928	7.568e-29	129.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,4HEYB@91061|Bacilli,27AE6@186823|Alicyclobacillaceae	91061|Bacilli	S	Putative membrane peptidase family (DUF2324)	yhfC	-	-	-	-	-	-	-	-	-	-	-	DUF2324
ZZS3_k127_4683595_10	1123073.KB899244_gene449	3.208e-38	148.0	COG0251@1|root,COG0251@2|Bacteria,1N917@1224|Proteobacteria,1SZKC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	ko:K10013	ko02010,map02010	M00225	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	-	Ribonuc_L-PSP
ZZS3_k127_4683595_5	379066.GAU_3042	1.468e-66	234.0	COG1896@1|root,COG1896@2|Bacteria,1ZU77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
ZZS3_k127_4717280_2	861299.J421_1360	2.371e-71	255.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_4717280_0	1304865.JAGF01000001_gene3317	1.346e-159	513.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_4717280_3	1278073.MYSTI_05535	2.245e-47	182.0	COG3564@1|root,COG3564@2|Bacteria,1RGYH@1224|Proteobacteria,42TFG@68525|delta/epsilon subdivisions,2X52K@28221|Deltaproteobacteria,2Z00X@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF779)	-	-	-	ko:K09959	-	-	-	-	ko00000	-	-	-	DUF779
ZZS3_k127_4717280_1	379066.GAU_3007	1.906e-110	358.0	COG1012@1|root,COG1012@2|Bacteria,1ZT7A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
ZZS3_k127_4779108_12	861299.J421_1150	1.557e-08	57.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS3_k127_4779108_7	264732.Moth_1354	5.274e-25	112.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,42GRM@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K13531	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
ZZS3_k127_4779108_0	379066.GAU_0146	3.454e-202	660.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria,1ZU8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
ZZS3_k127_4779108_14	399741.Spro_2392	1.8e-05	56.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,4015A@613|Serratia	1236|Gammaproteobacteria	KT	Bacterial regulatory protein, Fis family	stc	-	-	ko:K02688,ko:K10941,ko:K11914,ko:K21405	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	HTH_8,PAS_8,Sigma54_activat
ZZS3_k127_4779108_13	945713.IALB_1953	7.684e-08	63.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS3_k127_4779108_15	861299.J421_4437	3.653e-05	54.0	COG4970@1|root,COG4970@2|Bacteria,1ZU5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Tfp pilus assembly protein FimT	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4779108_10	861299.J421_1142	5.358e-16	88.0	COG2207@1|root,COG2207@2|Bacteria,1ZTPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ZZS3_k127_4779108_11	391625.PPSIR1_34113	6.578e-12	74.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
ZZS3_k127_4779108_6	379066.GAU_0196	2.063e-33	139.0	COG0789@1|root,COG0789@2|Bacteria,1ZTHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
ZZS3_k127_4779108_4	521045.Kole_1143	1.284e-54	198.0	COG1704@1|root,COG1704@2|Bacteria,2GCV5@200918|Thermotogae	200918|Thermotogae	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS3_k127_4779108_5	42256.RradSPS_0124	9.705e-51	196.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
ZZS3_k127_4779108_8	648885.KB316282_gene467	2.961e-20	104.0	COG0745@1|root,COG3920@1|root,COG0745@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,1JT80@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Histidine kinase	fsrR	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,Response_reg
ZZS3_k127_4779108_2	518766.Rmar_2362	1.919e-83	304.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1FJVU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Sulfatase
ZZS3_k127_4779108_9	1304872.JAGC01000007_gene2258	1.31e-17	99.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WKB3@28221|Deltaproteobacteria,2M8UC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
ZZS3_k127_4779108_1	1379270.AUXF01000002_gene1474	1.171e-88	304.0	COG3437@1|root,COG3437@2|Bacteria,1ZTD3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
ZZS3_k127_4779108_3	521674.Plim_1988	1.666e-58	206.0	COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS3_k127_4846696_5	861299.J421_2891	2.923e-139	450.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
ZZS3_k127_4846696_19	765420.OSCT_2916	9.069e-27	121.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi,375XQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
ZZS3_k127_4846696_0	1379270.AUXF01000003_gene3560	8.304e-252	795.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
ZZS3_k127_4846696_6	861299.J421_2890	1.921e-134	438.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
ZZS3_k127_4846696_18	861299.J421_2889	2.289e-29	126.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
ZZS3_k127_4846696_8	861299.J421_2888	5.551e-117	394.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
ZZS3_k127_4846696_15	1379270.AUXF01000005_gene391	1.985e-45	172.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ZZS3_k127_4846696_9	1379270.AUXF01000005_gene390	1.566e-114	372.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
ZZS3_k127_4846696_14	379066.GAU_1115	1.711e-55	203.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
ZZS3_k127_4846696_22	1379270.AUXF01000005_gene388	1.236e-16	86.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4846696_11	861299.J421_2883	5.648e-76	259.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
ZZS3_k127_4846696_21	861299.J421_2882	3.025e-20	96.0	COG0718@1|root,COG0718@2|Bacteria,1ZU1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
ZZS3_k127_4846696_4	861299.J421_2881	8.078e-144	475.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
ZZS3_k127_4846696_23	401053.AciPR4_2460	1.615e-13	77.0	COG4319@1|root,COG4319@2|Bacteria,3Y5FP@57723|Acidobacteria,2JN7M@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
ZZS3_k127_4846696_16	861299.J421_2878	1.032e-37	156.0	COG1295@1|root,COG1295@2|Bacteria,1ZTHX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ZZS3_k127_4846696_24	316067.Geob_3490	0.0005941	48.0	COG4980@1|root,COG4980@2|Bacteria,1NEPD@1224|Proteobacteria,42WE2@68525|delta/epsilon subdivisions,2WRDT@28221|Deltaproteobacteria,43SRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
ZZS3_k127_4846696_2	379066.GAU_1107	5.628e-182	580.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
ZZS3_k127_4846696_7	861299.J421_2873	5.017e-130	430.0	COG0166@1|root,COG0166@2|Bacteria,1ZU5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
ZZS3_k127_4846696_10	1379270.AUXF01000005_gene378	2.315e-100	332.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
ZZS3_k127_4846696_3	379066.GAU_1104	2.947e-151	492.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
ZZS3_k127_4846696_20	118166.JH976537_gene107	3.394e-23	108.0	COG1225@1|root,COG1225@2|Bacteria,1G2SK@1117|Cyanobacteria,1H9D2@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM AhpC TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS3_k127_4846696_17	861299.J421_1716	1.624e-37	156.0	COG0526@1|root,COG0526@2|Bacteria,1ZTV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
ZZS3_k127_4846696_12	379066.GAU_3579	8.016e-67	235.0	COG4232@1|root,COG4232@2|Bacteria,1ZSQP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Cytochrome C biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbD
ZZS3_k127_4846696_1	1382359.JIAL01000001_gene88	5.503e-194	612.0	COG0821@1|root,COG0821@2|Bacteria,3Y2GU@57723|Acidobacteria,2JHND@204432|Acidobacteriia	204432|Acidobacteriia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
ZZS3_k127_4846696_13	401053.AciPR4_3127	1.627e-60	214.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS3_k127_4894936_1	700598.Niako_1685	1.004e-82	280.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_4894936_0	296591.Bpro_2461	3.1e-170	556.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,4ADN4@80864|Comamonadaceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
ZZS3_k127_499497_9	861299.J421_3846	1.368e-16	86.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
ZZS3_k127_499497_7	926560.KE387023_gene2468	6.993e-35	138.0	COG1285@1|root,COG1285@2|Bacteria,1WMQN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
ZZS3_k127_499497_1	379066.GAU_2228	5.063e-67	247.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1ZSX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
ZZS3_k127_499497_0	378806.STAUR_5485	4.901e-128	424.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,42M1Z@68525|delta/epsilon subdivisions,2WJYC@28221|Deltaproteobacteria,2YXXR@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
ZZS3_k127_499497_6	290397.Adeh_0216	4.574e-40	162.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,42RNT@68525|delta/epsilon subdivisions,2WNHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_499497_3	1218076.BAYB01000001_gene34	1.499e-44	168.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
ZZS3_k127_499497_5	1123261.AXDW01000007_gene2309	5.625e-42	166.0	COG2885@1|root,COG2885@2|Bacteria,1NUID@1224|Proteobacteria,1SNFQ@1236|Gammaproteobacteria,1X6KY@135614|Xanthomonadales	135614|Xanthomonadales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
ZZS3_k127_5011942_44	358823.DF19_01265	0.0002185	50.0	COG0454@1|root,COG0456@2|Bacteria,2IFMH@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ZZS3_k127_5011942_24	861299.J421_3625	2.028e-40	156.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
ZZS3_k127_5011942_7	1356852.N008_14430	8.718e-148	485.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,47MN0@768503|Cytophagia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
ZZS3_k127_5011942_29	208444.JNYY01000025_gene5958	4.718e-27	115.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria,4E5E3@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
ZZS3_k127_5011942_14	403833.Pmob_0379	1.294e-75	265.0	COG0725@1|root,COG0725@2|Bacteria,2GCV7@200918|Thermotogae	200918|Thermotogae	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K15495	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	SBP_bac_11
ZZS3_k127_5011942_1	1144342.PMI40_01760	1.559e-224	712.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,2WH7P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
ZZS3_k127_5011942_23	472759.Nhal_3515	9.139e-43	166.0	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,1RNF7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Transport Permease Protein	pedC	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
ZZS3_k127_5011942_18	477974.Daud_1126	6.674e-57	217.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,2611J@186807|Peptococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_5011942_9	1380390.JIAT01000010_gene4342	1.19e-126	414.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
ZZS3_k127_5011942_37	1382306.JNIM01000001_gene927	2e-14	76.0	2E4CK@1|root,32Z81@2|Bacteria	2|Bacteria	S	pyrroloquinoline quinone biosynthesis protein D	pqqD	GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
ZZS3_k127_5011942_11	246196.MSMEI_3635	2.788e-86	292.0	COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria	201174|Actinobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
ZZS3_k127_5011942_13	526225.Gobs_2453	7.384e-78	270.0	COG1235@1|root,COG1235@2|Bacteria,2HBMA@201174|Actinobacteria	201174|Actinobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
ZZS3_k127_5011942_4	671143.DAMO_2793	2.347e-187	595.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	atoC	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
ZZS3_k127_5011942_6	671143.DAMO_2794	6.37e-159	515.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	icfG	-	2.7.13.3,3.1.3.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02660,ko:K03406,ko:K05874,ko:K07315,ko:K10819,ko:K11525,ko:K11617	ko00230,ko02020,ko02025,ko02030,ko04113,ko04213,map00230,map02020,map02025,map02030,map04113,map04213	M00481,M00695,M00754	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044,ko03021	-	-	-	EAL,GGDEF,Guanylate_cyc,HAMP,HATPase_c,HisKA,MCPsignal,SpoIIE,dCache_1
ZZS3_k127_5011942_33	1198114.AciX9_3732	1.191e-21	98.0	COG0614@1|root,COG0614@2|Bacteria,3Y8G5@57723|Acidobacteria	57723|Acidobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
ZZS3_k127_5011942_8	861299.J421_4211	5.924e-143	462.0	COG0457@1|root,COG0457@2|Bacteria,1ZSYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
ZZS3_k127_5011942_3	861299.J421_4207	9.075e-210	683.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS3_k127_5011942_32	1265507.KB899636_gene1927	1.962e-22	109.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1Y3N3@135624|Aeromonadales	135624|Aeromonadales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS3_k127_5011942_39	751994.AGIG01000008_gene1119	1.296e-09	68.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1J656@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325	CDP-OH_P_transf
ZZS3_k127_5011942_31	997346.HMPREF9374_2893	2.616e-23	107.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HJHJ@91061|Bacilli,27BV2@186824|Thermoactinomycetaceae	91061|Bacilli	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
ZZS3_k127_5011942_36	861299.J421_4201	9.2e-15	77.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5011942_22	1379270.AUXF01000001_gene2790	5.191e-43	165.0	COG1651@1|root,COG1651@2|Bacteria,1ZTKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
ZZS3_k127_5011942_30	861299.J421_4261	1.339e-23	106.0	COG4243@1|root,COG4243@2|Bacteria,1ZTVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
ZZS3_k127_5011942_2	1144275.COCOR_07655	4.576e-221	703.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
ZZS3_k127_5011942_0	1382356.JQMP01000004_gene583	6.034e-291	905.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS3_k127_5011942_40	861299.J421_3455	3.929e-08	59.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
ZZS3_k127_5011942_34	67257.JODR01000019_gene4015	8.261e-21	96.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_5011942_19	926569.ANT_19410	4.523e-48	182.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
ZZS3_k127_5011942_17	861299.J421_4191	8.924e-61	216.0	COG2386@1|root,COG2386@2|Bacteria,1ZTJ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
ZZS3_k127_5011942_15	861299.J421_4190	1.919e-74	257.0	COG0755@1|root,COG0755@2|Bacteria,1ZTJG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
ZZS3_k127_5011942_16	485913.Krac_11442	7.568e-63	225.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
ZZS3_k127_5011942_5	861299.J421_4185	2.346e-177	564.0	COG0304@1|root,COG0304@2|Bacteria,1ZTE1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS3_k127_5011942_21	1379270.AUXF01000001_gene2802	8.408e-46	182.0	COG2867@1|root,COG2867@2|Bacteria,1ZTVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
ZZS3_k127_5011942_26	379066.GAU_2589	1.063e-37	153.0	COG0500@1|root,COG2226@2|Bacteria,1ZTP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_5011942_25	1379270.AUXF01000001_gene2804	1.178e-38	156.0	COG1853@1|root,COG1853@2|Bacteria,1ZTVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
ZZS3_k127_5011942_12	1379270.AUXF01000001_gene2805	2.613e-84	294.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
ZZS3_k127_5011942_27	292459.STH1011	1.581e-37	153.0	COG0170@1|root,COG1836@1|root,COG0170@2|Bacteria,COG1836@2|Bacteria,1V7I1@1239|Firmicutes,24GQ3@186801|Clostridia	186801|Clostridia	I	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
ZZS3_k127_5011942_41	713587.THITH_00795	2.292e-07	57.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
ZZS3_k127_5011942_20	1379270.AUXF01000001_gene2568	7.922e-46	172.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_5011942_28	861299.J421_4179	9.848e-30	126.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5011942_10	379066.GAU_2584	5.45e-111	371.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
ZZS3_k127_5011942_38	861299.J421_4463	2.463e-10	71.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_5094477_8	869210.Marky_0121	3.021e-33	130.0	COG0350@1|root,COG0350@2|Bacteria,1WMTI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	FL	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
ZZS3_k127_5094477_7	886293.Sinac_5288	1.029e-33	135.0	COG2166@1|root,COG2166@2|Bacteria,2J0TJ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Fe-S metabolism associated	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
ZZS3_k127_5094477_4	1123366.TH3_01355	6.238e-113	376.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2JPVN@204441|Rhodospirillales	204441|Rhodospirillales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
ZZS3_k127_5094477_3	1121904.ARBP01000009_gene4348	1.161e-115	387.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_5094477_2	1191523.MROS_0721	1.879e-134	439.0	COG1932@1|root,COG1932@2|Bacteria	2|Bacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ZZS3_k127_5094477_1	1035308.AQYY01000001_gene2783	9.804e-138	449.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
ZZS3_k127_5094477_0	452637.Oter_3628	2.464e-138	451.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
ZZS3_k127_5094477_5	28258.KP05_00390	5.658e-101	348.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transport	yehZ	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
ZZS3_k127_5094477_6	1110502.TMO_1664	9.378e-43	161.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,2TTMA@28211|Alphaproteobacteria,2JRKI@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
ZZS3_k127_5106800_21	379066.GAU_2152	6.814e-135	435.0	COG0481@1|root,COG0481@2|Bacteria,1ZTGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,LepA_C
ZZS3_k127_5106800_55	1242864.D187_004797	9.225e-71	252.0	COG0697@1|root,COG0697@2|Bacteria,1PIF4@1224|Proteobacteria,42UWY@68525|delta/epsilon subdivisions,2WQX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_5106800_58	1122621.ATZA01000017_gene3936	6.429e-65	243.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS3_k127_5106800_65	1517416.IDAT_09545	4.219e-57	218.0	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,2QF7N@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ZZS3_k127_5106800_95	1499967.BAYZ01000009_gene5344	5.062e-08	64.0	COG1470@1|root,COG2885@1|root,COG1470@2|Bacteria,COG2885@2|Bacteria,2NPWP@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF4384,DUF4625,OmpA,PEGA
ZZS3_k127_5106800_41	861299.J421_3749	2.329e-91	310.0	COG1721@1|root,COG1721@2|Bacteria,1ZT0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
ZZS3_k127_5106800_77	1125863.JAFN01000001_gene501	3.891e-28	132.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	BatA,CARDB,F5_F8_type_C,HemolysinCabind,Laminin_G_3,NIDO,VWA_2
ZZS3_k127_5106800_5	518766.Rmar_2754	1.275e-240	782.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1FIP1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
ZZS3_k127_5106800_63	861299.J421_3746	4.731e-58	221.0	COG0760@1|root,COG0760@2|Bacteria,1ZT5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
ZZS3_k127_5106800_36	861299.J421_3745	1.326e-98	341.0	COG0760@1|root,COG0760@2|Bacteria,1ZSU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
ZZS3_k127_5106800_42	861299.J421_3744	2.859e-89	306.0	COG1995@1|root,COG1995@2|Bacteria,1ZT2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
ZZS3_k127_5106800_69	926550.CLDAP_37680	6.691e-52	191.0	COG0040@1|root,COG0040@2|Bacteria	2|Bacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
ZZS3_k127_5106800_70	1209989.TepiRe1_0718	1.139e-50	193.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,42FV2@68295|Thermoanaerobacterales	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
ZZS3_k127_5106800_24	1379270.AUXF01000003_gene3384	9.373e-120	401.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
ZZS3_k127_5106800_26	1504822.CCNO01000015_gene545	1.091e-113	384.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iNJ661.Rv1599,iSB619.SA_RS14140,iUTI89_1310.UTI89_C2293,iYO844.BSU34910,ic_1306.c2547	Histidinol_dh
ZZS3_k127_5106800_56	631454.N177_1657	1.504e-70	250.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,1JNAG@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
ZZS3_k127_5106800_2	1379270.AUXF01000003_gene3703	1.365e-277	868.0	COG1217@1|root,COG1217@2|Bacteria,1ZT8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
ZZS3_k127_5106800_49	627192.SLG_37070	9.059e-81	281.0	2DTTJ@1|root,32UVW@2|Bacteria,1NGQC@1224|Proteobacteria,2UKGP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
ZZS3_k127_5106800_50	1144275.COCOR_06857	3.046e-80	276.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_5106800_43	861299.J421_0143	3.808e-88	311.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ZZS3_k127_5106800_11	861299.J421_1737	2.078e-179	570.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
ZZS3_k127_5106800_30	290397.Adeh_0386	2.47e-107	364.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ZZS3_k127_5106800_16	861299.J421_1826	4.301e-156	507.0	COG1858@1|root,COG1858@2|Bacteria,1ZV0F@142182|Gemmatimonadetes	2|Bacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
ZZS3_k127_5106800_12	1379270.AUXF01000004_gene2919	3.424e-172	575.0	COG0515@1|root,COG0515@2|Bacteria,1ZUF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_5106800_59	861299.J421_1730	3.162e-63	225.0	COG1595@1|root,COG1595@2|Bacteria,1ZUWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
ZZS3_k127_5106800_80	1123508.JH636443_gene4871	9.07e-26	112.0	COG4191@1|root,COG4191@2|Bacteria,2IZNS@203682|Planctomycetes	203682|Planctomycetes	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
ZZS3_k127_5106800_92	1101190.ARWB01000001_gene2999	1.528e-10	64.0	2EFZF@1|root,339RM@2|Bacteria,1Q79X@1224|Proteobacteria,2UWHC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_79	640511.BC1002_6138	1.026e-26	127.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VM3J@28216|Betaproteobacteria,1KHSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_4,PAS_9
ZZS3_k127_5106800_31	314345.SPV1_07676	3.855e-107	371.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_5106800_37	661478.OP10G_0669	6.208e-96	320.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ZZS3_k127_5106800_57	661478.OP10G_0668	1.087e-68	242.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
ZZS3_k127_5106800_3	234267.Acid_6465	1.068e-276	885.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
ZZS3_k127_5106800_23	118166.JH976538_gene5057	5.378e-121	420.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
ZZS3_k127_5106800_96	861299.J421_0441	9.028e-08	64.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
ZZS3_k127_5106800_73	861299.J421_0442	4.976e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_5106800_32	926550.CLDAP_34140	1.107e-106	373.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
ZZS3_k127_5106800_29	404380.Gbem_2069	2.395e-107	371.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG3852@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria,43CGS@68525|delta/epsilon subdivisions,2X7RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,Response_reg
ZZS3_k127_5106800_9	251229.Chro_3457	1.19e-206	662.0	COG1352@1|root,COG5000@1|root,COG1352@2|Bacteria,COG5000@2|Bacteria,1G1W9@1117|Cyanobacteria,3VJGQ@52604|Pleurocapsales	1117|Cyanobacteria	NT	SPTR MCP methyltransferase, CheR-type with PAS PAC sensor	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheR,CheR_N,PAS,PAS_4,PAS_9
ZZS3_k127_5106800_68	163908.KB235896_gene2192	9.606e-55	200.0	COG2201@1|root,COG2201@2|Bacteria,1G50Z@1117|Cyanobacteria,1HIJH@1161|Nostocales	1117|Cyanobacteria	NT	PFAM CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
ZZS3_k127_5106800_34	1173028.ANKO01000159_gene5200	9.444e-100	336.0	COG2201@1|root,COG2201@2|Bacteria,1G3H5@1117|Cyanobacteria,1HAH2@1150|Oscillatoriales	1117|Cyanobacteria	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
ZZS3_k127_5106800_10	861299.J421_3703	1.166e-186	589.0	COG3185@1|root,COG3185@2|Bacteria,1ZT62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
ZZS3_k127_5106800_6	861299.J421_3702	2.622e-228	710.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
ZZS3_k127_5106800_1	379066.GAU_2126	5.488e-278	887.0	COG0365@1|root,COG0365@2|Bacteria,1ZSSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
ZZS3_k127_5106800_67	251229.Chro_0773	1.338e-56	206.0	COG0454@1|root,COG0456@2|Bacteria,1GQNY@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_5106800_8	204669.Acid345_3931	4.985e-216	681.0	COG3033@1|root,COG3033@2|Bacteria,3Y3QK@57723|Acidobacteria	57723|Acidobacteria	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
ZZS3_k127_5106800_0	935840.JAEQ01000003_gene70	1.319e-279	872.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
ZZS3_k127_5106800_48	935840.JAEQ01000003_gene71	5.532e-82	285.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,43JJK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
ZZS3_k127_5106800_71	543728.Vapar_0698	2.795e-48	179.0	COG2010@1|root,COG2010@2|Bacteria,1RHET@1224|Proteobacteria,2W3EV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
ZZS3_k127_5106800_27	861299.J421_1791	3.452e-112	371.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1ZT3S@142182|Gemmatimonadetes	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
ZZS3_k127_5106800_4	1287116.X734_05520	5.716e-257	808.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
ZZS3_k127_5106800_72	543728.Vapar_0695	2.107e-44	178.0	COG1845@1|root,COG1845@2|Bacteria,1RG95@1224|Proteobacteria,2VS0Y@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
ZZS3_k127_5106800_100	667632.KB890220_gene2858	0.0003949	52.0	28XAU@1|root,2ZJ8T@2|Bacteria,1PBIU@1224|Proteobacteria,2W6AX@28216|Betaproteobacteria,1K8VW@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_39	234267.Acid_6905	5.959e-95	323.0	COG3336@1|root,COG3336@2|Bacteria,3Y6N7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
ZZS3_k127_5106800_33	861299.J421_6166	3.095e-104	351.0	COG0628@1|root,COG0628@2|Bacteria,1ZSY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS3_k127_5106800_14	63737.Npun_R0136	2.995e-160	516.0	COG1914@1|root,COG1914@2|Bacteria,1G91I@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
ZZS3_k127_5106800_76	63737.Npun_R0135	4.873e-29	119.0	COG1873@1|root,COG1873@2|Bacteria,1GEUB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_89	497965.Cyan7822_0542	5.276e-15	80.0	2EM7X@1|root,33EX1@2|Bacteria,1GEMJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_66	861299.J421_1795	4.786e-57	211.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K06212,ko:K21990,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.4	-	-	Form_Nir_trans
ZZS3_k127_5106800_75	596323.HMPREF0554_0751	9.135e-33	135.0	COG5403@1|root,COG5403@2|Bacteria,37B87@32066|Fusobacteria	32066|Fusobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
ZZS3_k127_5106800_46	234267.Acid_4707	6.595e-83	290.0	COG0697@1|root,COG0697@2|Bacteria,3Y570@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_5106800_90	680198.SCAB_8361	2.784e-14	81.0	COG0115@1|root,COG0115@2|Bacteria,2IAFA@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
ZZS3_k127_5106800_87	439235.Dalk_0895	2.035e-17	90.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,sCache_2
ZZS3_k127_5106800_86	935866.JAER01000001_gene2712	1.642e-18	100.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF11,DUF4347
ZZS3_k127_5106800_84	525904.Tter_2777	7.101e-21	105.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6
ZZS3_k127_5106800_97	1254432.SCE1572_45995	1.403e-06	61.0	COG1413@1|root,COG1413@2|Bacteria,1QAW1@1224|Proteobacteria,43E4E@68525|delta/epsilon subdivisions,2WZPH@28221|Deltaproteobacteria,2Z2H1@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS3_k127_5106800_45	1128421.JAGA01000002_gene11	1.561e-83	292.0	COG4277@1|root,COG4277@2|Bacteria	2|Bacteria	-	-	MA20_15955	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	HHH_3,Radical_SAM
ZZS3_k127_5106800_38	448385.sce6976	4.232e-95	339.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
ZZS3_k127_5106800_7	404589.Anae109_3731	2.704e-221	713.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
ZZS3_k127_5106800_64	1279009.ADICEAN_00839	3.805e-57	225.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos,ShlB
ZZS3_k127_5106800_40	1254432.SCE1572_37590	3.34e-94	326.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
ZZS3_k127_5106800_25	1254432.SCE1572_02795	2.271e-117	397.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS3_k127_5106800_53	861299.J421_1605	1.167e-73	254.0	COG4119@1|root,COG4119@2|Bacteria	2|Bacteria	L	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
ZZS3_k127_5106800_20	861299.J421_1663	4e-139	456.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
ZZS3_k127_5106800_47	1485544.JQKP01000001_gene1305	1.26e-82	282.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria,44WBP@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_5106800_83	379066.GAU_2139	1.389e-21	103.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Response_reg
ZZS3_k127_5106800_18	1379270.AUXF01000001_gene2850	3.756e-146	493.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	ASH,CARDB,F5_F8_type_C,PKD,PPC,Peptidase_C2,Peptidase_M66,Peptidase_S8,fn3
ZZS3_k127_5106800_82	317936.Nos7107_1630	6.809e-22	105.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Cu_amine_oxidN1
ZZS3_k127_5106800_54	1379270.AUXF01000003_gene3813	2.489e-73	257.0	COG1173@1|root,COG1173@2|Bacteria,1ZTI1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_5106800_52	1519464.HY22_02230	2.119e-75	265.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_5106800_22	861299.J421_3637	2.51e-134	443.0	COG0747@1|root,COG0747@2|Bacteria,1ZTAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_5106800_61	1128421.JAGA01000002_gene806	1.827e-60	223.0	COG2605@1|root,COG2605@2|Bacteria	1128421.JAGA01000002_gene806|-	G	GHMP kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_19	861299.J421_3636	1.875e-144	492.0	2AEF2@1|root,314A1@2|Bacteria,1ZSNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
ZZS3_k127_5106800_44	379066.GAU_2040	4.621e-85	297.0	COG0001@1|root,COG0001@2|Bacteria,1ZSWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_5106800_28	861299.J421_3633	3.079e-108	356.0	COG2159@1|root,COG2159@2|Bacteria,1ZSXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
ZZS3_k127_5106800_62	861299.J421_3632	2.814e-60	217.0	COG2159@1|root,COG2159@2|Bacteria,1ZTHS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_60	935845.JADQ01000007_gene1676	4.621e-61	226.0	COG0329@1|root,COG0329@2|Bacteria,1U034@1239|Firmicutes,4I9D8@91061|Bacilli,271D2@186822|Paenibacillaceae	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
ZZS3_k127_5106800_35	521045.Kole_0683	1.767e-99	340.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4,Fer4_21
ZZS3_k127_5106800_51	521045.Kole_0682	1.3e-77	274.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
ZZS3_k127_5106800_13	861299.J421_3641	1.149e-162	544.0	COG0383@1|root,COG0383@2|Bacteria,1ZT4Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38
ZZS3_k127_5106800_15	379066.GAU_3769	6.938e-160	515.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ZZS3_k127_5106800_74	926550.CLDAP_10560	1.942e-35	144.0	COG3346@1|root,COG3346@2|Bacteria,2G8X9@200795|Chloroflexi	200795|Chloroflexi	S	SURF1 family	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
ZZS3_k127_5106800_91	1379270.AUXF01000002_gene1173	8.28e-14	81.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
ZZS3_k127_5106800_81	861299.J421_2924	4.56e-25	122.0	COG4932@1|root,COG4932@2|Bacteria,1ZUFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	-
ZZS3_k127_5106800_85	530564.Psta_4082	6.678e-19	102.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,SdrD_B
ZZS3_k127_5106800_94	65393.PCC7424_5117	3.068e-10	72.0	COG1749@1|root,COG1749@2|Bacteria,1G2ZW@1117|Cyanobacteria	1117|Cyanobacteria	N	Ig domain protein group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,DUF4082
ZZS3_k127_5106800_101	1189619.pgond44_14433	0.0008513	51.0	COG2133@1|root,COG2374@1|root,COG2133@2|Bacteria,COG2374@2|Bacteria,4PPQZ@976|Bacteroidetes,1IKS9@117743|Flavobacteriia,4C338@83612|Psychroflexus	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5106800_88	471853.Bcav_2782	3.9e-16	92.0	COG1404@1|root,COG2911@1|root,COG4932@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,2GYXK@201174|Actinobacteria	201174|Actinobacteria	M	Invasin, domain 3	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Invasin_D3
ZZS3_k127_5106800_17	1254432.SCE1572_22505	1.101e-146	482.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS3_k127_5106800_78	861299.J421_3846	2.316e-27	115.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
ZZS3_k127_5190549_1	1192034.CAP_4860	2.789e-43	165.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YXMW@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG type nucleases (URI domain)	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	UVR
ZZS3_k127_5190549_2	379066.GAU_2436	5.771e-38	149.0	COG0622@1|root,COG0622@2|Bacteria,1ZTSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
ZZS3_k127_5190549_0	880073.Calab_3513	2.275e-85	297.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	pip	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Peptidase_S9
ZZS3_k127_5190549_3	1379270.AUXF01000003_gene3488	6.009e-22	96.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ZZS3_k127_5208967_63	379066.GAU_1452	2.311e-16	92.0	2F0K0@1|root,33TNP@2|Bacteria,1ZTJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_55	1262914.BN533_00043	1.841e-35	141.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4H5BU@909932|Negativicutes	909932|Negativicutes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
ZZS3_k127_5208967_9	1379270.AUXF01000005_gene704	3.808e-147	477.0	COG1015@1|root,COG1015@2|Bacteria,1ZTG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
ZZS3_k127_5208967_40	861299.J421_3093	1.778e-67	245.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
ZZS3_k127_5208967_33	861299.J421_3092	2.961e-75	261.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
ZZS3_k127_5208967_3	379066.GAU_1447	2.171e-181	577.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
ZZS3_k127_5208967_64	1463917.JODC01000034_gene8353	8.008e-15	88.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
ZZS3_k127_5208967_5	1379698.RBG1_1C00001G0402	3.387e-170	557.0	COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria	2|Bacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
ZZS3_k127_5208967_24	379066.GAU_1442	1.639e-93	316.0	COG0552@1|root,COG0552@2|Bacteria,1ZTBT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
ZZS3_k127_5208967_47	861299.J421_3082	4.26e-53	209.0	COG1572@1|root,COG1572@2|Bacteria,1ZSTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_46	1128421.JAGA01000002_gene1042	4.157e-55	205.0	COG0106@1|root,COG0106@2|Bacteria,2NPEY@2323|unclassified Bacteria	2|Bacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS3_k127_5208967_29	861299.J421_3081	2.321e-83	298.0	COG0739@1|root,COG0739@2|Bacteria,1ZSUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS3_k127_5208967_4	861299.J421_3080	1.046e-173	556.0	COG0206@1|root,COG0206@2|Bacteria,1ZSNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
ZZS3_k127_5208967_15	861299.J421_3079	6.895e-126	421.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
ZZS3_k127_5208967_53	861299.J421_3078	3.609e-38	159.0	COG1589@1|root,COG1589@2|Bacteria,1ZTRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
ZZS3_k127_5208967_18	861299.J421_3077	1.917e-120	404.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_5208967_27	379066.GAU_1428	3.793e-88	304.0	COG0707@1|root,COG0707@2|Bacteria,1ZSW5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
ZZS3_k127_5208967_34	330214.NIDE0760	1.862e-73	263.0	COG0772@1|root,COG0772@2|Bacteria,3J0M8@40117|Nitrospirae	40117|Nitrospirae	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
ZZS3_k127_5208967_13	861299.J421_3074	1.531e-129	431.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
ZZS3_k127_5208967_10	861299.J421_3073	4.464e-137	445.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
ZZS3_k127_5208967_26	861299.J421_3072	1.356e-88	314.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_5208967_8	861299.J421_3071	1.99e-148	484.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ZZS3_k127_5208967_16	861299.J421_3070	9.134e-124	421.0	COG0768@1|root,COG0768@2|Bacteria,1ZSYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
ZZS3_k127_5208967_70	861299.J421_3069	1.894e-06	53.0	29F5Y@1|root,3023N@2|Bacteria,1ZU6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_23	379066.GAU_1420	1.068e-93	318.0	COG0275@1|root,COG0275@2|Bacteria,1ZT4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
ZZS3_k127_5208967_58	861299.J421_3065	1.189e-32	138.0	2DUTE@1|root,33S5W@2|Bacteria,1ZSMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_32	1379270.AUXF01000005_gene678	8.459e-78	269.0	COG0457@1|root,COG0457@2|Bacteria,1ZTK5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
ZZS3_k127_5208967_60	665942.HMPREF1022_02247	1.059e-21	103.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria,2MB3S@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	CheW-like domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS3_k127_5208967_68	868595.Desca_1833	7.491e-07	59.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,2623N@186807|Peptococcaceae	186801|Clostridia	NT	PFAM CheW domain protein	CheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS3_k127_5208967_30	1379270.AUXF01000005_gene676	4.133e-80	279.0	COG2201@1|root,COG2201@2|Bacteria,1ZUFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
ZZS3_k127_5208967_57	1379270.AUXF01000005_gene675	1.347e-34	140.0	COG1871@1|root,COG1871@2|Bacteria,1ZV29@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
ZZS3_k127_5208967_38	861299.J421_3062	2.05e-68	241.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
ZZS3_k127_5208967_12	1379270.AUXF01000005_gene674	2.575e-130	434.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
ZZS3_k127_5208967_17	379066.GAU_1411	2.222e-121	417.0	COG0593@1|root,COG0593@2|Bacteria,1ZUFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA
ZZS3_k127_5208967_31	861299.J421_3059	2.381e-78	269.0	COG1100@1|root,COG1100@2|Bacteria,1ZTK3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
ZZS3_k127_5208967_67	1379698.RBG1_1C00001G1744	1.506e-07	63.0	COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
ZZS3_k127_5208967_69	357808.RoseRS_0773	1.684e-06	57.0	COG2018@1|root,COG2018@2|Bacteria,2G9R6@200795|Chloroflexi,375PX@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
ZZS3_k127_5208967_71	77586.LPERR02G13670.1	2.851e-05	55.0	COG3914@1|root,KOG4626@2759|Eukaryota,37RD4@33090|Viridiplantae,3G7FD@35493|Streptophyta,3KQHT@4447|Liliopsida,3I8JI@38820|Poales	35493|Streptophyta	GOT	Glycosyl transferase family 41	-	-	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,LEA_5,TPR_1,TPR_11,TPR_7,TPR_8
ZZS3_k127_5208967_54	1128421.JAGA01000002_gene21	1.893e-36	151.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
ZZS3_k127_5208967_22	1379270.AUXF01000005_gene670	1.194e-112	396.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
ZZS3_k127_5208967_43	861299.J421_3056	7.836e-61	216.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
ZZS3_k127_5208967_14	861299.J421_3055	4.775e-128	431.0	COG0643@1|root,COG0643@2|Bacteria,1ZT7R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	P2 response regulator binding domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
ZZS3_k127_5208967_42	379066.GAU_1405	7.143e-61	213.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ZZS3_k127_5208967_66	697303.Thewi_2215	1.334e-08	62.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,42F87@68295|Thermoanaerobacterales	186801|Clostridia	NT	SMART CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ZZS3_k127_5208967_28	379066.GAU_1403	4.629e-85	301.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ZZS3_k127_5208967_52	379066.GAU_1401	1.312e-41	164.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
ZZS3_k127_5208967_44	861299.J421_3049	1.016e-58	207.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
ZZS3_k127_5208967_0	861299.J421_3048	0.0	1074.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
ZZS3_k127_5208967_21	379066.GAU_1398	1.555e-113	372.0	COG0005@1|root,COG0005@2|Bacteria,1ZUII@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
ZZS3_k127_5208967_62	300852.55771946	4.947e-17	89.0	COG3599@1|root,COG3599@2|Bacteria,1WJUV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	PFAM DivIVA protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
ZZS3_k127_5208967_48	643562.Daes_0255	2.231e-51	192.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MB0W@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
ZZS3_k127_5208967_25	861299.J421_2988	2.488e-91	329.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_36	861299.J421_3043	2.132e-72	261.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
ZZS3_k127_5208967_1	861299.J421_3042	2.428e-266	834.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
ZZS3_k127_5208967_35	1379270.AUXF01000005_gene655	4.943e-73	253.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
ZZS3_k127_5208967_50	246197.MXAN_4360	2.416e-48	191.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
ZZS3_k127_5208967_20	1379270.AUXF01000001_gene2850	1.513e-115	408.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	ASH,CARDB,F5_F8_type_C,PKD,PPC,Peptidase_C2,Peptidase_M66,Peptidase_S8,fn3
ZZS3_k127_5208967_37	224911.27355053	2.003e-69	244.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,3JR3Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS3_k127_5208967_51	290397.Adeh_0987	4.249e-43	162.0	2B7KW@1|root,320RZ@2|Bacteria,1RFFB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_11	234267.Acid_5076	5.591e-131	425.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
ZZS3_k127_5208967_49	1340493.JNIF01000004_gene473	3.45e-49	182.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_61	1254432.SCE1572_21780	1.979e-18	91.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2YUC3@29|Myxococcales	28221|Deltaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
ZZS3_k127_5208967_65	861299.J421_3012	6.021e-13	73.0	COG2919@1|root,COG2919@2|Bacteria,1ZU6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Septum formation initiator	-	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
ZZS3_k127_5208967_2	861299.J421_3011	2.589e-187	595.0	COG0148@1|root,COG0148@2|Bacteria,1ZTAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
ZZS3_k127_5208967_41	861299.J421_3009	5.066e-62	226.0	COG0611@1|root,COG0611@2|Bacteria,1ZTIU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS3_k127_5208967_72	345073.VC395_1472	0.0001103	55.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1XW8K@135623|Vibrionales	135623|Vibrionales	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
ZZS3_k127_5208967_39	861299.J421_3008	4.715e-68	250.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1ZTAT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
ZZS3_k127_5208967_59	861299.J421_3007	9.232e-28	113.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_56	1379270.AUXF01000005_gene601	4.634e-35	141.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5208967_6	1089548.KI783301_gene3099	4.086e-165	535.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3WE62@539002|Bacillales incertae sedis	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
ZZS3_k127_5208967_45	1379270.AUXF01000005_gene599	4.388e-57	204.0	COG0698@1|root,COG0698@2|Bacteria,1ZUTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
ZZS3_k127_5208967_7	861299.J421_3004	6.678e-153	495.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
ZZS3_k127_5208967_19	1379270.AUXF01000005_gene596	1.677e-116	382.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
ZZS3_k127_5212126_14	1379270.AUXF01000003_gene3488	4.789e-64	226.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ZZS3_k127_5212126_9	861299.J421_3905	7.924e-93	317.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
ZZS3_k127_5212126_0	861299.J421_3906	7.736e-248	775.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
ZZS3_k127_5212126_12	861299.J421_3907	3.066e-71	248.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
ZZS3_k127_5212126_10	861299.J421_3908	1.445e-82	279.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_5212126_20	861299.J421_3909	7.059e-05	52.0	2F9A9@1|root,341MC@2|Bacteria,1ZU0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5212126_17	861299.J421_3910	5.952e-23	113.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ZZS3_k127_5212126_16	861299.J421_3911	3.125e-35	153.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
ZZS3_k127_5212126_15	1267535.KB906767_gene341	1.595e-47	179.0	28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
ZZS3_k127_5212126_13	861299.J421_3913	5.168e-66	235.0	COG1912@1|root,COG1912@2|Bacteria,1ZTIH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
ZZS3_k127_5212126_7	1379270.AUXF01000003_gene3479	7.573e-123	404.0	COG0489@1|root,COG0489@2|Bacteria,1ZSW7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
ZZS3_k127_5212126_19	99598.Cal7507_4954	4.112e-15	77.0	COG0694@1|root,COG0694@2|Bacteria,1G7UJ@1117|Cyanobacteria,1HP8I@1161|Nostocales	1117|Cyanobacteria	O	PFAM NifU-like domain	nifU	-	-	-	-	-	-	-	-	-	-	-	NifU
ZZS3_k127_5212126_8	861299.J421_3916	3.756e-94	320.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS3_k127_5212126_4	886293.Sinac_4878	7.87e-173	554.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS3_k127_5212126_3	1123008.KB905692_gene63	2.94e-177	569.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,2FPUV@200643|Bacteroidia,22WHW@171551|Porphyromonadaceae	976|Bacteroidetes	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
ZZS3_k127_5212126_1	1379270.AUXF01000003_gene3474	1.068e-240	751.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
ZZS3_k127_5212126_6	1123508.JH636440_gene2646	2.188e-130	441.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_5212126_2	861299.J421_1043	4.197e-181	593.0	COG0467@1|root,COG0467@2|Bacteria,1ZUWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
ZZS3_k127_5212126_5	204669.Acid345_3285	2.2e-159	518.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JIFD@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS3_k127_5212126_18	861299.J421_3920	9.024e-16	81.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5212126_11	861299.J421_3922	5.463e-75	258.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
ZZS3_k127_5240437_4	1379270.AUXF01000002_gene1717	6.368e-134	452.0	COG5001@1|root,COG5001@2|Bacteria,1ZT12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS
ZZS3_k127_5240437_20	926550.CLDAP_33370	6.021e-26	111.0	COG0500@1|root,COG2226@2|Bacteria,2G948@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
ZZS3_k127_5240437_15	937777.Deipe_2119	7.944e-45	167.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
ZZS3_k127_5240437_11	234267.Acid_5195	6.975e-65	225.0	2EHG8@1|root,33B84@2|Bacteria,3Y808@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5240437_14	1379270.AUXF01000002_gene1305	1.351e-50	186.0	COG4636@1|root,COG4636@2|Bacteria,1ZV4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ZZS3_k127_5240437_22	1038859.AXAU01000003_gene6191	4.872e-18	93.0	2FGTF@1|root,348NS@2|Bacteria,1P2M9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5240437_25	1173024.KI912148_gene3545	2.746e-07	53.0	COG2827@1|root,COG2827@2|Bacteria,1G9KB@1117|Cyanobacteria	1117|Cyanobacteria	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
ZZS3_k127_5240437_3	469383.Cwoe_1309	5.338e-159	515.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
ZZS3_k127_5240437_2	945713.IALB_0608	2.085e-168	561.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
ZZS3_k127_5240437_9	797302.Halru_2444	1.715e-76	269.0	arCOG05130@1|root,arCOG05130@2157|Archaea,2XZ27@28890|Euryarchaeota,23Y3Y@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5240437_0	861299.J421_0622	5.278e-231	724.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
ZZS3_k127_5240437_13	861299.J421_0621	9.698e-54	198.0	2AI77@1|root,318MJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5240437_19	1380370.JIBA01000018_gene463	6.758e-28	122.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ZZS3_k127_5240437_5	1123508.JH636445_gene6557	1.062e-122	423.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_5240437_10	1144275.COCOR_02148	3.833e-71	258.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_5240437_8	1382304.JNIL01000001_gene3204	1.501e-76	262.0	COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
ZZS3_k127_5240437_6	671143.DAMO_2906	9.196e-119	394.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,SdrD_B,TIG,fn3_3
ZZS3_k127_5240437_24	1449044.JMLE01000030_gene8	3.068e-10	64.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	3.2.2.10	ko:K06966,ko:K07089,ko:K07402	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF2318,XdhC_C,XdhC_CoxI,YHS
ZZS3_k127_5240437_1	1267535.KB906767_gene5147	2.042e-175	572.0	COG1793@1|root,COG1793@2|Bacteria,3Y3AP@57723|Acidobacteria,2JIGV@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
ZZS3_k127_5240437_7	861299.J421_6371	1.979e-110	389.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6371|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
ZZS3_k127_5240437_12	861299.J421_4544	1.365e-56	211.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_5240437_18	1144275.COCOR_01063	4.857e-33	135.0	COG0596@1|root,COG0596@2|Bacteria,1QVBQ@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5240437_21	935836.JAEL01000042_gene4929	2.773e-25	114.0	COG5516@1|root,COG5516@2|Bacteria,1V9PX@1239|Firmicutes,4HK9T@91061|Bacilli,1ZBYC@1386|Bacillus	91061|Bacilli	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
ZZS3_k127_5240437_16	861299.J421_3651	1.505e-39	154.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	yqjI	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	PadR
ZZS3_k127_5240437_17	379066.GAU_2992	1.318e-35	145.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ZZS3_k127_5245640_9	246197.MXAN_3891	7.696e-82	284.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YXT2@29|Myxococcales	28221|Deltaproteobacteria	E	Group II decarboxylase family protein	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,Pyridoxal_deC
ZZS3_k127_5245640_17	926550.CLDAP_07270	1.355e-34	136.0	2DT85@1|root,33J4K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5245640_16	324602.Caur_1959	8.808e-35	141.0	2E3MN@1|root,33PAQ@2|Bacteria,2G91W@200795|Chloroflexi,377MD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5245640_5	472759.Nhal_3311	8.129e-153	500.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
ZZS3_k127_5245640_11	1163408.UU9_08852	9.41e-77	280.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X3IK@135614|Xanthomonadales	135614|Xanthomonadales	CQ	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrome_CBB3
ZZS3_k127_5245640_13	330214.NIDE1563	3.478e-45	182.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	cpxA	-	2.7.13.3	ko:K02484,ko:K07640,ko:K07643,ko:K07645,ko:K07649,ko:K19609	ko01503,ko02020,ko02024,map01503,map02020,map02024	M00447,M00451,M00453,M00457,M00721,M00722,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,CpxA_peri,HAMP,HATPase_c,HK_sensor,HisKA
ZZS3_k127_5245640_18	443144.GM21_0227	2.358e-32	132.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,43SE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_5245640_4	861299.J421_1919	1.963e-164	524.0	COG2132@1|root,COG2132@2|Bacteria,1ZTWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_5245640_15	1144275.COCOR_04390	5.134e-41	160.0	COG0398@1|root,COG0398@2|Bacteria,1N99S@1224|Proteobacteria	1224|Proteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS3_k127_5245640_2	370438.PTH_1459	5.287e-197	649.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,260I9@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
ZZS3_k127_5245640_0	269799.Gmet_0770	5.777e-292	917.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,43SWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS3_k127_5245640_19	1140.Synpcc7942_1824	1.344e-16	85.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1H08Q@1129|Synechococcus	1117|Cyanobacteria	S	CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
ZZS3_k127_5245640_6	204669.Acid345_0206	1.149e-107	368.0	COG2989@1|root,COG2989@2|Bacteria,3Y2YW@57723|Acidobacteria,2JIFK@204432|Acidobacteriia	2|Bacteria	S	ErfK YbiS YcfS YnhG family protein	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
ZZS3_k127_5245640_10	511062.GU3_04920	5.796e-77	267.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1Y4YM@135624|Aeromonadales	135624|Aeromonadales	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
ZZS3_k127_5245640_1	502025.Hoch_0325	1.131e-226	726.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,42PQC@68525|delta/epsilon subdivisions,2WJ8K@28221|Deltaproteobacteria,2YY7H@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_5245640_8	502025.Hoch_0326	8.988e-95	328.0	COG0845@1|root,COG0845@2|Bacteria,1PZST@1224|Proteobacteria,42R2S@68525|delta/epsilon subdivisions,2WMVJ@28221|Deltaproteobacteria,2Z0BJ@29|Myxococcales	28221|Deltaproteobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
ZZS3_k127_5245640_14	215803.DB30_0119	8.84e-45	173.0	2CK59@1|root,32VV2@2|Bacteria,1P616@1224|Proteobacteria,4329Y@68525|delta/epsilon subdivisions,2X772@28221|Deltaproteobacteria,2YVDY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5245640_12	639030.JHVA01000001_gene3713	4.219e-61	218.0	COG2823@1|root,COG2823@2|Bacteria,3Y7T6@57723|Acidobacteria,2JN0K@204432|Acidobacteriia	204432|Acidobacteriia	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
ZZS3_k127_5245640_7	1379270.AUXF01000003_gene3657	3.85e-95	323.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
ZZS3_k127_5245640_3	596154.Alide2_2726	1.706e-188	601.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,4AB63@80864|Comamonadaceae	28216|Betaproteobacteria	F	thymidine phosphorylase	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
ZZS3_k127_5245640_20	1235457.C404_26130	2.797e-11	71.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2VJI6@28216|Betaproteobacteria,1K6IC@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
ZZS3_k127_5253583_6	861299.J421_3227	2.913e-113	368.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
ZZS3_k127_5253583_15	861299.J421_3226	2.769e-61	224.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
ZZS3_k127_5253583_17	861299.J421_3225	3.765e-44	168.0	COG2121@1|root,COG2121@2|Bacteria,1ZTU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
ZZS3_k127_5253583_13	671143.DAMO_1646	1.86e-73	269.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
ZZS3_k127_5253583_10	1379270.AUXF01000006_gene298	2.026e-93	322.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
ZZS3_k127_5253583_11	861299.J421_3222	4.638e-91	315.0	COG1043@1|root,COG1043@2|Bacteria,1ZT7T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
ZZS3_k127_5253583_3	379066.GAU_1588	7.769e-149	485.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
ZZS3_k127_5253583_9	861299.J421_3220	5.901e-95	322.0	COG1044@1|root,COG1044@2|Bacteria,1ZSRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
ZZS3_k127_5253583_19	1379270.AUXF01000006_gene302	7.915e-21	98.0	COG2825@1|root,COG2825@2|Bacteria,1ZU5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
ZZS3_k127_5253583_1	861299.J421_3218	7.865e-216	696.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
ZZS3_k127_5253583_0	886293.Sinac_6482	2.201e-307	967.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
ZZS3_k127_5253583_4	1379270.AUXF01000006_gene305	1.088e-132	432.0	COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
ZZS3_k127_5253583_22	699246.HMPREF0868_0470	1.449e-05	54.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
ZZS3_k127_5253583_12	861299.J421_3214	6.573e-83	286.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
ZZS3_k127_5253583_7	861299.J421_3213	2.059e-111	374.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
ZZS3_k127_5253583_2	1121430.JMLG01000037_gene147	1.563e-158	516.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
ZZS3_k127_5253583_5	861299.J421_3211	3.6e-131	428.0	COG1186@1|root,COG1186@2|Bacteria,1ZTE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ZZS3_k127_5253583_18	861299.J421_3210	8.209e-41	161.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
ZZS3_k127_5253583_8	379066.GAU_1576	1.759e-96	325.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ZZS3_k127_5253583_20	861299.J421_3206	5.438e-20	91.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
ZZS3_k127_5253583_14	1379270.AUXF01000006_gene315	1.099e-69	248.0	COG1159@1|root,COG1159@2|Bacteria,1ZUSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
ZZS3_k127_5253583_16	234267.Acid_1271	7.951e-56	213.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
ZZS3_k127_5253583_21	1122921.KB898189_gene724	7.176e-07	53.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5481775_8	1123368.AUIS01000029_gene1283	2.862e-36	139.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,2NCU3@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
ZZS3_k127_5481775_0	1379270.AUXF01000006_gene151	0.0	1061.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1ZU89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
ZZS3_k127_5481775_3	1379270.AUXF01000006_gene152	1.789e-164	535.0	COG0034@1|root,COG0034@2|Bacteria,1ZTD7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6
ZZS3_k127_5481775_1	1379270.AUXF01000006_gene153	6.091e-269	849.0	COG0046@1|root,COG0046@2|Bacteria,1ZT8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS3_k127_5481775_9	861299.J421_3379	4.888e-20	95.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
ZZS3_k127_5481775_5	379066.GAU_1736	5.539e-82	279.0	COG0047@1|root,COG0047@2|Bacteria,1ZTF8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
ZZS3_k127_5481775_10	861299.J421_3377	1.182e-19	91.0	COG1828@1|root,COG1828@2|Bacteria,1ZU3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
ZZS3_k127_5481775_7	379066.GAU_1734	2.277e-60	221.0	COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
ZZS3_k127_5481775_6	861299.J421_3375	1.164e-62	225.0	COG0688@1|root,COG0688@2|Bacteria,1ZU9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
ZZS3_k127_5481775_4	1040989.AWZU01000018_gene2780	1.4e-116	385.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TS0T@28211|Alphaproteobacteria,3JRJ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC2	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
ZZS3_k127_5481775_2	379066.GAU_1731	9.089e-168	541.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
ZZS3_k127_5502592_3	215803.DB30_7824	6.891e-08	64.0	COG2353@1|root,COG2353@2|Bacteria,1Q3RK@1224|Proteobacteria,439JF@68525|delta/epsilon subdivisions,2X4W2@28221|Deltaproteobacteria,2YZQD@29|Myxococcales	28221|Deltaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
ZZS3_k127_5502592_2	1379698.RBG1_1C00001G0797	4.706e-38	163.0	COG4191@1|root,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
ZZS3_k127_5502592_1	56780.SYN_01954	7.434e-59	228.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
ZZS3_k127_5502592_0	690850.Desaf_2891	2.066e-67	238.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MCTY@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ZZS3_k127_5509385_2	1128421.JAGA01000002_gene903	1.594e-93	319.0	COG0182@1|root,COG0182@2|Bacteria,2NNM7@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
ZZS3_k127_5509385_1	379066.GAU_0818	5.544e-178	576.0	COG0554@1|root,COG0554@2|Bacteria,1ZTX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
ZZS3_k127_5509385_4	861299.J421_2741	1.779e-47	175.0	COG2332@1|root,COG2332@2|Bacteria,1ZTNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
ZZS3_k127_5509385_0	1379270.AUXF01000004_gene3075	4.261e-258	811.0	COG1138@1|root,COG1138@2|Bacteria,1ZTBY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
ZZS3_k127_5509385_5	861299.J421_2743	1.363e-25	113.0	COG3088@1|root,COG3088@2|Bacteria,1ZTS7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
ZZS3_k127_5509385_6	1379270.AUXF01000004_gene3073	4.24e-24	112.0	29W2Z@1|root,30HMM@2|Bacteria,1ZTXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5509385_7	266117.Rxyl_0093	2.417e-08	62.0	COG0784@1|root,COG2202@1|root,COG4585@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HisKA_3,PAS_3,PAS_9,Response_reg
ZZS3_k127_5509385_3	314278.NB231_00265	3.797e-93	311.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria,1X0JC@135613|Chromatiales	135613|Chromatiales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
ZZS3_k127_5519213_6	379066.GAU_1710	1.188e-45	172.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
ZZS3_k127_5519213_0	331869.BAL199_17673	2.248e-160	508.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,2TTMH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
ZZS3_k127_5519213_4	1196031.ALEG01000028_gene4132	3.189e-56	208.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HF69@91061|Bacilli,1ZQ3B@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_5519213_3	378806.STAUR_7457	1.314e-73	252.0	COG3832@1|root,COG3832@2|Bacteria,1MZXG@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_5519213_5	378806.STAUR_7458	4.889e-46	168.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,43AM1@68525|delta/epsilon subdivisions,2X616@28221|Deltaproteobacteria,2Z388@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_5519213_1	1337936.IJ00_02250	3.143e-128	415.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
ZZS3_k127_5519213_2	861299.J421_1634	1.434e-86	299.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
ZZS3_k127_5776813_30	706587.Desti_2385	4.877e-16	81.0	COG0510@1|root,COG0510@2|Bacteria,1NUSY@1224|Proteobacteria,4309F@68525|delta/epsilon subdivisions,2WV5P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	thiamine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5776813_16	1123368.AUIS01000038_gene40	1.961e-54	195.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_9,Glycos_transf_2,Hydrolase_like
ZZS3_k127_5776813_2	448385.sce6792	6.376e-161	510.0	COG0451@1|root,COG0451@2|Bacteria,1Q4V9@1224|Proteobacteria,42YHQ@68525|delta/epsilon subdivisions,2WUA6@28221|Deltaproteobacteria,2YY4T@29|Myxococcales	28221|Deltaproteobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
ZZS3_k127_5776813_14	1123368.AUIS01000005_gene436	9.402e-57	206.0	COG0406@1|root,COG0406@2|Bacteria,1N5BK@1224|Proteobacteria,1T885@1236|Gammaproteobacteria,2NCFA@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ZZS3_k127_5776813_1	404589.Anae109_3226	1.545e-188	606.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2YXI2@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	msbA9	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ZZS3_k127_5776813_8	1121468.AUBR01000005_gene22	3.794e-82	287.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
ZZS3_k127_5776813_35	714083.JH370377_gene2501	3.531e-06	59.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4FKS8@85023|Microbacteriaceae	201174|Actinobacteria	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
ZZS3_k127_5776813_28	1392487.JIAD01000001_gene969	5.084e-17	85.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,25WUG@186806|Eubacteriaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ZZS3_k127_5776813_6	379066.GAU_0768	1.953e-83	285.0	COG1435@1|root,COG1435@2|Bacteria,1ZTB2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
ZZS3_k127_5776813_17	1379270.AUXF01000004_gene3113	5.232e-54	196.0	COG0237@1|root,COG0237@2|Bacteria,1ZTM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
ZZS3_k127_5776813_20	1379270.AUXF01000004_gene3114	1.952e-43	164.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
ZZS3_k127_5776813_0	861299.J421_2685	0.0	1294.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1ZSUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
ZZS3_k127_5776813_21	861299.J421_2684	7.137e-39	157.0	COG0095@1|root,COG0095@2|Bacteria,1ZTY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS3_k127_5776813_11	861299.J421_3721	9.946e-73	273.0	COG0747@1|root,COG0747@2|Bacteria,1ZUDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ZZS3_k127_5776813_12	1192868.CAIU01000008_gene1040	6.42e-66	237.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQJC@28211|Alphaproteobacteria,43GT6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_5776813_10	861299.J421_2681	3.159e-73	259.0	COG1173@1|root,COG1173@2|Bacteria,1ZTMP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ZZS3_k127_5776813_4	1379270.AUXF01000004_gene3120	8.032e-112	374.0	COG0444@1|root,COG0444@2|Bacteria,1ZSWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
ZZS3_k127_5776813_3	926561.KB900620_gene2915	4.616e-125	408.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ZZS3_k127_5776813_15	379066.GAU_0311	4.488e-56	205.0	COG1191@1|root,COG1191@2|Bacteria,1ZSY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
ZZS3_k127_5776813_9	1379270.AUXF01000002_gene1474	4.051e-75	267.0	COG3437@1|root,COG3437@2|Bacteria,1ZTD3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
ZZS3_k127_5776813_18	927677.ALVU02000001_gene1596	5.207e-53	189.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
ZZS3_k127_5776813_5	1173028.ANKO01000244_gene3949	1.958e-108	357.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales	1117|Cyanobacteria	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
ZZS3_k127_5776813_19	1122223.KB890700_gene1966	1.725e-50	181.0	COG0073@1|root,COG0073@2|Bacteria,1WK6S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Export-related chaperone CsaA	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
ZZS3_k127_5776813_34	1499967.BAYZ01000117_gene3342	3.688e-07	59.0	COG0739@1|root,COG0739@2|Bacteria,2NRWS@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Peptidase_M23
ZZS3_k127_5776813_7	1128421.JAGA01000003_gene3178	1.23e-82	286.0	COG2362@1|root,COG2362@2|Bacteria,2NPDW@2323|unclassified Bacteria	2|Bacteria	E	D-aminopeptidase	dppA	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	iYO844.BSU12920	Peptidase_M55
ZZS3_k127_5776813_24	1500893.JQNB01000001_gene3454	4.447e-26	113.0	COG4899@1|root,COG4899@2|Bacteria,1QD43@1224|Proteobacteria,1T8ZH@1236|Gammaproteobacteria,1XBFV@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
ZZS3_k127_5776813_33	338969.Rfer_0153	1.959e-08	63.0	COG3797@1|root,COG3797@2|Bacteria,1RG1D@1224|Proteobacteria,2VRF0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
ZZS3_k127_5776813_31	1196835.A458_03450	4.601e-15	81.0	2C1V6@1|root,2ZVAI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5776813_13	1385935.N836_00540	1.965e-62	221.0	COG2860@1|root,COG2860@2|Bacteria,1GD1U@1117|Cyanobacteria	1117|Cyanobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
ZZS3_k127_5776813_26	1122605.KB893626_gene2770	3.503e-19	91.0	2F60U@1|root,33YJ8@2|Bacteria,4P494@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
ZZS3_k127_5776813_29	1122605.KB893626_gene2771	1.26e-16	82.0	COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes,1IU8R@117747|Sphingobacteriia	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
ZZS3_k127_5776813_27	1122605.KB893648_gene3540	8.601e-19	92.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2
ZZS3_k127_5776813_22	1121920.AUAU01000005_gene976	1.574e-38	147.0	2E31H@1|root,32Y1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5776813_23	1380394.JADL01000001_gene2170	7.71e-33	132.0	COG0346@1|root,COG0346@2|Bacteria,1NFR3@1224|Proteobacteria,2UMIM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
ZZS3_k127_5783004_7	861299.J421_3995	3.048e-25	106.0	2DING@1|root,303QG@2|Bacteria,1ZV8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
ZZS3_k127_5783004_5	861299.J421_2221	7.453e-33	143.0	2ECQU@1|root,336NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PHP
ZZS3_k127_5783004_1	290397.Adeh_0005	1.197e-120	396.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS3_k127_5783004_12	314345.SPV1_03883	0.0003431	49.0	297U0@1|root,2ZV0P@2|Bacteria,1P6ZH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5783004_10	379066.GAU_2745	1.5e-08	60.0	2CA9X@1|root,2ZJY8@2|Bacteria,1ZU1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5783004_9	379066.GAU_0167	6.609e-18	86.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
ZZS3_k127_5783004_11	1033802.SSPSH_000620	1.358e-05	57.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,1SBRG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
ZZS3_k127_5783004_0	880073.Calab_2932	1.888e-137	459.0	COG0077@1|root,COG2876@1|root,COG0077@2|Bacteria,COG2876@2|Bacteria,2NNPG@2323|unclassified Bacteria	2|Bacteria	E	PFAM DAHP synthetase I KDSA	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	2.5.1.54,4.2.1.51,5.4.99.5	ko:K03856,ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R00691,R01373,R01715,R01826	RC00360,RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_2667	CM_2,PDT
ZZS3_k127_5783004_6	1267533.KB906740_gene378	5.01e-31	127.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
ZZS3_k127_5783004_8	1123073.KB899241_gene1794	4.669e-19	98.0	COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales	135614|Xanthomonadales	O	PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
ZZS3_k127_5783004_4	743721.Psesu_0513	4.044e-38	150.0	COG1595@1|root,COG1595@2|Bacteria,1QDHS@1224|Proteobacteria,1SS07@1236|Gammaproteobacteria,1X6DE@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_5783004_2	945713.IALB_0512	1.009e-112	376.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
ZZS3_k127_5783004_3	861299.J421_1277	2.602e-111	367.0	COG4294@1|root,COG4294@2|Bacteria	2|Bacteria	L	response to UV	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
ZZS3_k127_5842334_2	489825.LYNGBM3L_51530	1.424e-117	395.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
ZZS3_k127_5842334_4	886293.Sinac_2856	1.018e-23	106.0	29FX8@1|root,32K0S@2|Bacteria,2J157@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5842334_3	1122970.AUHC01000004_gene2341	1.447e-47	193.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2U3F9@28211|Alphaproteobacteria,2K2U7@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
ZZS3_k127_5842334_1	1380354.JIAN01000005_gene1630	3.253e-131	429.0	COG0753@1|root,COG0753@2|Bacteria,2I4NI@201174|Actinobacteria	201174|Actinobacteria	P	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5936230_1	861299.J421_3894	9.203e-138	448.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_5936230_0	379066.GAU_2427	4.741e-266	831.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
ZZS3_k127_5936230_8	1382359.JIAL01000001_gene1613	6.585e-29	121.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria,2JJWZ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ZZS3_k127_5936230_5	296591.Bpro_2639	1.629e-59	217.0	COG1917@1|root,COG1917@2|Bacteria,1RH0Y@1224|Proteobacteria,2VWWA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5936230_4	234267.Acid_7368	1.01e-77	270.0	COG2220@1|root,COG2220@2|Bacteria,3Y2TV@57723|Acidobacteria	57723|Acidobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS3_k127_5936230_7	1123508.JH636445_gene6821	1.737e-50	184.0	COG1490@1|root,COG1490@2|Bacteria,2IZJI@203682|Planctomycetes	203682|Planctomycetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
ZZS3_k127_5936230_6	861299.J421_3871	5.212e-53	198.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
ZZS3_k127_5936230_3	861299.J421_3868	5.65e-120	410.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1ZT7U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
ZZS3_k127_5936230_9	1123058.KB894227_gene49	3.06e-23	104.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1I44S@117743|Flavobacteriia	976|Bacteroidetes	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_5936230_2	56780.SYN_01947	1.605e-136	451.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2MQ88@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
ZZS3_k127_5984173_20	861299.J421_0824	9.521e-12	66.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	catD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
ZZS3_k127_5984173_3	861299.J421_0859	3.577e-134	437.0	COG0346@1|root,COG0346@2|Bacteria,1ZTUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_5984173_6	1128421.JAGA01000001_gene2190	2.305e-104	348.0	COG0346@1|root,COG0346@2|Bacteria,2NR6J@2323|unclassified Bacteria	2|Bacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_5984173_10	861299.J421_2172	1.076e-85	288.0	COG0400@1|root,COG0400@2|Bacteria,1ZTXT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
ZZS3_k127_5984173_12	1267534.KB906756_gene712	5.645e-57	207.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5984173_4	706587.Desti_0932	1.309e-132	437.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
ZZS3_k127_5984173_7	251229.Chro_1450	5.248e-101	341.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999,ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
ZZS3_k127_5984173_16	1121895.Q765_13945	5.306e-27	120.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1HYT4@117743|Flavobacteriia,2NTH0@237|Flavobacterium	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
ZZS3_k127_5984173_11	584708.Apau_2033	2.11e-79	280.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_5984173_19	314345.SPV1_10411	2.291e-19	94.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_5984173_5	1254432.SCE1572_02795	5.457e-122	411.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS3_k127_5984173_15	648996.Theam_1157	3.399e-37	148.0	COG0132@1|root,COG0132@2|Bacteria,2G468@200783|Aquificae	200783|Aquificae	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
ZZS3_k127_5984173_9	1379698.RBG1_1C00001G0798	9.29e-88	324.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
ZZS3_k127_5984173_13	479434.Sthe_0472	1.473e-53	196.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi,27YAF@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
ZZS3_k127_5984173_14	562970.Btus_1455	3.706e-45	166.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
ZZS3_k127_5984173_8	861299.J421_3824	1.197e-89	301.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
ZZS3_k127_5984173_17	861299.J421_3825	4.483e-24	108.0	COG0806@1|root,COG0806@2|Bacteria,1ZU43@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
ZZS3_k127_5984173_18	572547.Amico_0552	4.579e-23	105.0	COG0228@1|root,COG0228@2|Bacteria,3TBDH@508458|Synergistetes	508458|Synergistetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
ZZS3_k127_5984173_0	861299.J421_3827	2.839e-188	599.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
ZZS3_k127_5984173_1	861299.J421_5759	3.507e-148	497.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_5984173_2	861299.J421_3829	8.842e-136	443.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
ZZS3_k127_5990944_13	414684.RC1_1221	4.169e-78	265.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2JQMB@204441|Rhodospirillales	204441|Rhodospirillales	L	COG2818 3-methyladenine DNA glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
ZZS3_k127_5990944_8	1192034.CAP_4435	6.32e-97	327.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_5990944_23	1121918.ARWE01000001_gene2296	6.796e-51	198.0	COG0389@1|root,COG0389@2|Bacteria,1RBTJ@1224|Proteobacteria,42QY9@68525|delta/epsilon subdivisions,2WMTI@28221|Deltaproteobacteria,43S6H@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	impB/mucB/samB family	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
ZZS3_k127_5990944_24	1353531.AZNX01000002_gene4794	1.345e-48	177.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,2UD6F@28211|Alphaproteobacteria,4BF9Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	bleomycin resistance protein	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
ZZS3_k127_5990944_14	861299.J421_5976	5.396e-74	263.0	COG1533@1|root,COG1533@2|Bacteria,1ZUFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS3_k127_5990944_40	1408419.JHYG01000006_gene2643	3.428e-05	49.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2JQ7S@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
ZZS3_k127_5990944_37	292415.Tbd_2454	1.447e-25	121.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,2WBSA@28216|Betaproteobacteria,1KSGD@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
ZZS3_k127_5990944_21	558152.IQ37_11810	4.564e-61	214.0	2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,1I8KU@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_5990944_4	1123368.AUIS01000024_gene954	6.291e-148	482.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
ZZS3_k127_5990944_20	652103.Rpdx1_1192	9.028e-65	231.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,3K48K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
ZZS3_k127_5990944_35	379066.GAU_2648	6.149e-30	124.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
ZZS3_k127_5990944_9	163908.KB235896_gene3940	1.748e-91	312.0	COG2267@1|root,COG2267@2|Bacteria,1G2EN@1117|Cyanobacteria,1HM72@1161|Nostocales	1117|Cyanobacteria	I	PFAM Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ZZS3_k127_5990944_18	379066.GAU_3732	1.274e-68	251.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
ZZS3_k127_5990944_29	861299.J421_2069	4.087e-42	157.0	COG0234@1|root,COG0234@2|Bacteria,1ZU6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
ZZS3_k127_5990944_28	861299.J421_0057	7.454e-45	169.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
ZZS3_k127_5990944_17	861299.J421_1157	6.71e-69	240.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
ZZS3_k127_5990944_11	1382306.JNIM01000001_gene4037	2.277e-88	303.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
ZZS3_k127_5990944_1	1379270.AUXF01000002_gene1826	3.632e-260	814.0	COG0843@1|root,COG0843@2|Bacteria,1ZSMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
ZZS3_k127_5990944_19	861299.J421_2409	1.371e-68	240.0	COG1845@1|root,COG1845@2|Bacteria,1ZT8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
ZZS3_k127_5990944_38	861299.J421_2410	9.095e-14	77.0	2EKS3@1|root,33EFV@2|Bacteria,1ZTY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
ZZS3_k127_5990944_15	861299.J421_2411	8.749e-72	257.0	COG3336@1|root,COG3336@2|Bacteria,1ZT56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
ZZS3_k127_5990944_27	404589.Anae109_0402	1.587e-45	169.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,42UHB@68525|delta/epsilon subdivisions,2WQHM@28221|Deltaproteobacteria,2YVPY@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
ZZS3_k127_5990944_26	1233950.IW22_24410	1.067e-45	174.0	2AKCX@1|root,31B42@2|Bacteria,4P1TT@976|Bacteroidetes,1IHFI@117743|Flavobacteriia,3ZU5G@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_5990944_7	1379270.AUXF01000003_gene3643	4.043e-117	383.0	COG1028@1|root,COG1028@2|Bacteria,1ZT7P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_5990944_30	1192034.CAP_1263	9.649e-42	164.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,42SEY@68525|delta/epsilon subdivisions,2WPN4@28221|Deltaproteobacteria,2YV2J@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
ZZS3_k127_5990944_36	861299.J421_2528	1.48e-29	123.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1ZSVI@142182|Gemmatimonadetes	2|Bacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,MASE4,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1,dCache_2
ZZS3_k127_5990944_5	1379270.AUXF01000001_gene2028	2.118e-130	422.0	COG0623@1|root,COG0623@2|Bacteria,1ZTGW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_5990944_2	379066.GAU_2114	1.949e-208	678.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_5990944_12	1185876.BN8_05036	1.959e-85	297.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_5990944_16	518766.Rmar_0540	3.587e-69	242.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1FJCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
ZZS3_k127_5990944_6	479433.Caci_8801	4.95e-119	395.0	COG0520@1|root,COG0520@2|Bacteria,2H9MG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ZZS3_k127_5990944_32	926560.KE387023_gene2038	3.29e-39	153.0	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ZZS3_k127_5990944_22	483219.LILAB_02920	8.316e-55	206.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
ZZS3_k127_5990944_33	751945.Theos_0407	2.53e-38	148.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
ZZS3_k127_5990944_0	518766.Rmar_0089	0.0	1222.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
ZZS3_k127_5990944_31	748247.AZKH_3947	2.323e-39	152.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2VRA0@28216|Betaproteobacteria,2M02W@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
ZZS3_k127_5990944_10	706587.Desti_0852	4.656e-90	329.0	COG2203@1|root,COG4191@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,43BYI@68525|delta/epsilon subdivisions,2X79E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
ZZS3_k127_5990944_34	234267.Acid_3320	6.479e-33	149.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
ZZS3_k127_5990944_25	1094980.Mpsy_2813	4.39e-48	187.0	COG0628@1|root,arCOG02642@2157|Archaea,2XT00@28890|Euryarchaeota,2NAEQ@224756|Methanomicrobia	224756|Methanomicrobia	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ZZS3_k127_5990944_3	1144275.COCOR_03147	4.783e-180	574.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
ZZS3_k127_5990944_39	1210884.HG799472_gene14857	2.749e-13	73.0	COG0667@1|root,COG0667@2|Bacteria,2IX8H@203682|Planctomycetes	203682|Planctomycetes	C	oxidoreductases (related to aryl-alcohol	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_6156901_22	1089553.Tph_c02780	6.648e-110	367.0	COG0438@1|root,COG0707@1|root,COG0438@2|Bacteria,COG0707@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ZZS3_k127_6156901_30	192952.MM_0768	6.54e-69	246.0	arCOG14740@1|root,arCOG14740@2157|Archaea,2Y46U@28890|Euryarchaeota	28890|Euryarchaeota	S	TupA-like ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_TupA
ZZS3_k127_6156901_21	1173027.Mic7113_1861	4.128e-112	373.0	COG0438@1|root,COG0438@2|Bacteria,1G27U@1117|Cyanobacteria,1H99H@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_6156901_32	402777.KB235904_gene2812	7.711e-62	233.0	COG0500@1|root,COG2226@2|Bacteria,1G2V9@1117|Cyanobacteria,1HAFQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
ZZS3_k127_6156901_26	247490.KSU1_C0431	1.509e-103	358.0	COG2244@1|root,COG2244@2|Bacteria,2J1D3@203682|Planctomycetes	203682|Planctomycetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
ZZS3_k127_6156901_38	357804.Ping_0437	4.626e-24	115.0	COG4424@1|root,COG4424@2|Bacteria,1N2S4@1224|Proteobacteria,1SI6D@1236|Gammaproteobacteria,2QHX8@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
ZZS3_k127_6156901_28	118161.KB235922_gene223	2.677e-92	314.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3VJFW@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
ZZS3_k127_6156901_33	649638.Trad_2751	1.585e-58	214.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
ZZS3_k127_6156901_3	391625.PPSIR1_33429	2.026e-196	626.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,2YWBV@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
ZZS3_k127_6156901_35	118168.MC7420_7002	7.044e-47	181.0	COG3011@1|root,COG3011@2|Bacteria,1GBBP@1117|Cyanobacteria,1HDV0@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
ZZS3_k127_6156901_13	1236959.BAMT01000004_gene774	1.383e-146	471.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,2KKT8@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
ZZS3_k127_6156901_18	859657.RPSI07_2021	4.766e-126	410.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,1K08X@119060|Burkholderiaceae	28216|Betaproteobacteria	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
ZZS3_k127_6156901_17	1183438.GKIL_3877	4.065e-127	412.0	COG0555@1|root,COG0555@2|Bacteria,1FZVV@1117|Cyanobacteria	1117|Cyanobacteria	O	Sulfate ABC transporter, permease protein CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
ZZS3_k127_6156901_10	243231.GSU1346	1.869e-153	491.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,42N4E@68525|delta/epsilon subdivisions,2WUQU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfate ABC transporter, periplasmic sulfate-binding protein	cysP	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
ZZS3_k127_6156901_27	1278073.MYSTI_05277	4.301e-101	347.0	COG3746@1|root,COG3746@2|Bacteria,1N2GT@1224|Proteobacteria,42W61@68525|delta/epsilon subdivisions,2WRSI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
ZZS3_k127_6156901_36	316067.Geob_1650	3.105e-45	175.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,43ABU@68525|delta/epsilon subdivisions,2WVAV@28221|Deltaproteobacteria,43UYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ZZS3_k127_6156901_9	1121335.Clst_0173	2.536e-162	515.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3WJJK@541000|Ruminococcaceae	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
ZZS3_k127_6156901_31	861299.J421_6047	5.104e-66	229.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,DUF2061
ZZS3_k127_6156901_29	216594.MMAR_4258	8.918e-84	287.0	COG1218@1|root,COG1218@2|Bacteria,2INUC@201174|Actinobacteria	201174|Actinobacteria	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
ZZS3_k127_6156901_1	574087.Acear_2132	7.259e-252	790.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WBKH@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
ZZS3_k127_6156901_34	338963.Pcar_1464	2.124e-54	218.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WN1C@28221|Deltaproteobacteria,43S7E@69541|Desulfuromonadales	28221|Deltaproteobacteria	DM	Chain length determinant protein	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
ZZS3_k127_6156901_39	1163617.SCD_n02949	2.796e-15	84.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2VKB3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
ZZS3_k127_6156901_40	661478.OP10G_0951	4.698e-12	79.0	COG1520@1|root,COG2319@1|root,COG1520@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	KAP_NTPase,WD40
ZZS3_k127_6156901_19	665571.STHERM_c15680	4.284e-117	388.0	COG0438@1|root,COG0438@2|Bacteria,2J8DI@203691|Spirochaetes	203691|Spirochaetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_6156901_0	1173027.Mic7113_5255	4.403e-265	831.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ZZS3_k127_6156901_24	379066.GAU_0777	9.09e-104	348.0	COG0454@1|root,COG0454@2|Bacteria,1ZSVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_6156901_8	861299.J421_2697	2.217e-163	546.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
ZZS3_k127_6156901_25	861299.J421_2696	1.127e-103	349.0	COG0420@1|root,COG0420@2|Bacteria,1ZSPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
ZZS3_k127_6156901_2	1379270.AUXF01000004_gene3104	7.628e-250	787.0	COG0433@1|root,COG0433@2|Bacteria,1ZURZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_6156901_37	861299.J421_2693	9.75e-34	145.0	COG2380@1|root,COG2380@2|Bacteria,1ZUZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6156901_41	1172188.KB911824_gene3392	3.357e-10	66.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4FFSK@85021|Intrasporangiaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,TPR_12
ZZS3_k127_6156901_12	243231.GSU1815	2.133e-148	476.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	uxs	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS3_k127_6156901_5	1123368.AUIS01000005_gene419	4.104e-176	558.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,1SZKP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ZZS3_k127_6156901_11	448385.sce6772	2.339e-152	492.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,42NV5@68525|delta/epsilon subdivisions,2WM5C@28221|Deltaproteobacteria,2YYZF@29|Myxococcales	28221|Deltaproteobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ZZS3_k127_6156901_15	365046.Rta_16020	1.51e-132	430.0	COG1063@1|root,COG1063@2|Bacteria,1MUK8@1224|Proteobacteria,2W0EF@28216|Betaproteobacteria,4AGM5@80864|Comamonadaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_6156901_14	670292.JH26_26595	5.985e-135	443.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2TUGN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS3_k127_6156901_20	1123368.AUIS01000005_gene422	3.851e-116	387.0	COG0438@1|root,COG0438@2|Bacteria,1Q3IF@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_6156901_7	1123368.AUIS01000005_gene423	3.51e-165	530.0	COG4641@1|root,COG4641@2|Bacteria,1MY6E@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_transf_4
ZZS3_k127_6156901_4	1123368.AUIS01000005_gene424	8.411e-181	572.0	COG4641@1|root,COG4641@2|Bacteria,1MXSZ@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ZZS3_k127_6156901_6	1123368.AUIS01000005_gene446	7.996e-174	554.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	ykvP	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
ZZS3_k127_6156901_23	316067.Geob_3248	1.624e-107	354.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria	1224|Proteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
ZZS3_k127_6156901_16	1123368.AUIS01000001_gene1885	4.336e-129	430.0	COG0510@1|root,COG0510@2|Bacteria,1NUSY@1224|Proteobacteria	1224|Proteobacteria	M	thiamine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6245415_0	1479237.JMLY01000001_gene2005	2.051e-224	725.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
ZZS3_k127_6245415_8	379066.GAU_1913	1.495e-52	196.0	COG4464@1|root,COG4464@2|Bacteria,1ZTQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
ZZS3_k127_6245415_9	861299.J421_3519	8.308e-50	188.0	COG0279@1|root,COG0279@2|Bacteria,1ZTY5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
ZZS3_k127_6245415_5	861299.J421_3518	4.834e-76	271.0	COG1028@1|root,COG1028@2|Bacteria,1ZTJK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_6245415_6	861299.J421_3517	6.992e-75	263.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
ZZS3_k127_6245415_4	861299.J421_3513	1.303e-99	338.0	COG0617@1|root,COG0617@2|Bacteria,1ZSKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
ZZS3_k127_6245415_7	1379698.RBG1_1C00001G1352	1.901e-56	205.0	COG0428@1|root,COG0428@2|Bacteria,2NQ6J@2323|unclassified Bacteria	2|Bacteria	P	ZIP Zinc transporter	zupT	-	-	ko:K07238,ko:K11021,ko:K16267	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5	-	-	Zip
ZZS3_k127_6245415_1	861299.J421_3508	1.018e-190	604.0	COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
ZZS3_k127_6245415_12	379066.GAU_1908	2.214e-20	98.0	COG5608@1|root,COG5608@2|Bacteria,1ZTWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
ZZS3_k127_6245415_3	861299.J421_3506	4.034e-135	443.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
ZZS3_k127_6245415_11	1382304.JNIL01000001_gene1280	1.511e-39	162.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,2785H@186823|Alicyclobacillaceae	91061|Bacilli	C	Phosphoenolpyruvate phosphomutase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
ZZS3_k127_6245415_10	269800.Tfu_2464	1.148e-49	188.0	COG0500@1|root,COG2226@2|Bacteria,2IMHF@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
ZZS3_k127_6245415_2	861299.J421_2473	5.357e-186	586.0	COG0673@1|root,COG0673@2|Bacteria,1ZSQ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ZZS3_k127_6245415_13	317619.ANKN01000106_gene3618	6.435e-11	64.0	COG1088@1|root,COG1088@2|Bacteria,1G045@1117|Cyanobacteria,1MKTJ@1212|Prochloraceae	1117|Cyanobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS3_k127_6263213_0	861299.J421_5846	3.168e-272	855.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_6263213_7	861299.J421_0973	7.78e-77	261.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	yiiE	-	-	-	-	-	-	-	-	-	-	-	DUF1211
ZZS3_k127_6263213_4	1082933.MEA186_27600	5.477e-152	484.0	COG4271@1|root,COG4271@2|Bacteria,1R4Z7@1224|Proteobacteria	1224|Proteobacteria	K	nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like,cNMP_binding
ZZS3_k127_6263213_2	2074.JNYD01000003_gene3439	7.538e-223	697.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4E9Y4@85010|Pseudonocardiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
ZZS3_k127_6263213_10	1123319.AUBE01000007_gene3673	9.72e-38	150.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
ZZS3_k127_6263213_1	420324.KI912082_gene6957	6.67e-239	743.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,1JUZ2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
ZZS3_k127_6263213_8	172088.AUGA01000003_gene5734	6.038e-52	187.0	COG1917@1|root,COG1917@2|Bacteria,1RCXV@1224|Proteobacteria,2U6MY@28211|Alphaproteobacteria,3JYZJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_6263213_3	1267534.KB906759_gene1883	3.696e-185	586.0	COG1064@1|root,COG1064@2|Bacteria	2|Bacteria	P	alcohol dehydrogenase	adhC	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
ZZS3_k127_6263213_9	68223.JNZY01000008_gene2943	1.073e-50	189.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
ZZS3_k127_6263213_5	485913.Krac_0550	5.275e-95	316.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
ZZS3_k127_6263213_6	395961.Cyan7425_1172	3.865e-78	268.0	COG1733@1|root,COG1733@2|Bacteria,1GBX0@1117|Cyanobacteria	1117|Cyanobacteria	K	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
ZZS3_k127_6263213_11	469383.Cwoe_2408	3.039e-23	105.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
ZZS3_k127_6266321_6	379066.GAU_2504	9.905e-136	454.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6266321_4	861299.J421_1886	8.29e-141	458.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
ZZS3_k127_6266321_17	379066.GAU_2847	1.558e-54	205.0	2ARQH@1|root,31H1J@2|Bacteria,1ZUJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
ZZS3_k127_6266321_15	1144275.COCOR_02829	5.999e-58	214.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	yktD	GO:0002682,GO:0002684,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K16038	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09856	RC00003,RC02842	ko00000,ko00001,ko01000	-	-	-	LCM
ZZS3_k127_6266321_23	330214.NIDE4362	2.682e-34	138.0	COG1611@1|root,COG1611@2|Bacteria,3J0TX@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	-
ZZS3_k127_6266321_12	1173264.KI913949_gene41	2.235e-62	222.0	COG0726@1|root,COG0726@2|Bacteria,1G5ZR@1117|Cyanobacteria	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ZZS3_k127_6266321_27	748247.AZKH_3363	1.316e-15	78.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria,2W531@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
ZZS3_k127_6266321_8	861299.J421_5709	1.061e-85	311.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_16,Trans_reg_C
ZZS3_k127_6266321_26	1123389.ATXJ01000002_gene1641	1.97e-16	86.0	COG5339@1|root,COG5339@2|Bacteria,1WNF1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
ZZS3_k127_6266321_5	1379270.AUXF01000006_gene199	3.637e-136	452.0	COG0260@1|root,COG0260@2|Bacteria,1ZSPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
ZZS3_k127_6266321_28	1379270.AUXF01000006_gene200	4.022e-15	89.0	COG4206@1|root,COG4206@2|Bacteria,1ZT1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
ZZS3_k127_6266321_9	861299.J421_0787	8.159e-80	276.0	COG0631@1|root,COG0631@2|Bacteria,1ZSPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS3_k127_6266321_10	1237149.C900_05696	1.153e-66	253.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
ZZS3_k127_6266321_13	861299.J421_3322	7.804e-61	222.0	COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
ZZS3_k127_6266321_16	861299.J421_3321	3.744e-55	202.0	COG0194@1|root,COG0194@2|Bacteria,1ZTV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
ZZS3_k127_6266321_25	1379270.AUXF01000006_gene203	1.297e-16	81.0	28VAR@1|root,2ZHDJ@2|Bacteria,1ZU25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
ZZS3_k127_6266321_7	861299.J421_3319	8.168e-121	403.0	COG0452@1|root,COG0452@2|Bacteria,1ZV19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
ZZS3_k127_6266321_11	379066.GAU_1687	1.071e-62	228.0	COG1573@1|root,COG1573@2|Bacteria,1ZTG5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ZZS3_k127_6266321_0	1379270.AUXF01000006_gene205	4.345e-177	566.0	COG0305@1|root,COG0305@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
ZZS3_k127_6266321_1	861299.J421_3316	2.489e-176	563.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
ZZS3_k127_6266321_20	861299.J421_3315	1.833e-48	188.0	COG1211@1|root,COG1211@2|Bacteria,1ZSTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
ZZS3_k127_6266321_14	861299.J421_3314	7.592e-59	211.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
ZZS3_k127_6266321_21	379066.GAU_1682	7.908e-41	156.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
ZZS3_k127_6266321_22	1173028.ANKO01000227_gene1253	1.795e-39	160.0	COG0169@1|root,COG0169@2|Bacteria,1G0CS@1117|Cyanobacteria,1H8SN@1150|Oscillatoriales	1117|Cyanobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
ZZS3_k127_6266321_24	335543.Sfum_3894	2.988e-27	121.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2MRUJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
ZZS3_k127_6266321_3	379066.GAU_1679	1.063e-150	482.0	COG0057@1|root,COG0057@2|Bacteria,1ZSTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ZZS3_k127_6266321_2	861299.J421_3309	1.602e-155	501.0	COG0126@1|root,COG0126@2|Bacteria,1ZT1B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
ZZS3_k127_6266321_19	861299.J421_3308	5.785e-50	183.0	COG0149@1|root,COG0149@2|Bacteria,1ZSYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
ZZS3_k127_6268703_6	234267.Acid_0372	1.185e-157	512.0	COG3104@1|root,COG3104@2|Bacteria,3Y6W5@57723|Acidobacteria	57723|Acidobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
ZZS3_k127_6268703_41	1379270.AUXF01000004_gene3124	3.61e-19	95.0	2FDPQ@1|root,345QV@2|Bacteria,1ZU3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_29	543728.Vapar_3381	1.277e-49	185.0	COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,2VRYZ@28216|Betaproteobacteria,4ADYE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_18	479434.Sthe_0831	9.454e-82	277.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
ZZS3_k127_6268703_2	1173024.KI912151_gene2146	1.142e-191	608.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
ZZS3_k127_6268703_17	215803.DB30_1157	3.294e-83	284.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,439ZV@68525|delta/epsilon subdivisions,2X2Y1@28221|Deltaproteobacteria,2YWXH@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
ZZS3_k127_6268703_31	266117.Rxyl_1963	1.68e-49	188.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CQH3@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
ZZS3_k127_6268703_26	861299.J421_2675	3.899e-55	201.0	2ED0A@1|root,336X9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_16	357808.RoseRS_3026	1.791e-90	323.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
ZZS3_k127_6268703_28	1125863.JAFN01000001_gene535	3.315e-50	194.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_6268703_27	861299.J421_2674	2.176e-54	200.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
ZZS3_k127_6268703_32	379066.GAU_1207	3.846e-49	185.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
ZZS3_k127_6268703_13	861299.J421_2672	1.6e-110	366.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_45	861299.J421_2670	3.978e-06	51.0	296V5@1|root,2ZU41@2|Bacteria,1ZU78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_24	246197.MXAN_4231	9.576e-61	223.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
ZZS3_k127_6268703_42	316273.XCV2601	1.544e-15	87.0	COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
ZZS3_k127_6268703_23	1166018.FAES_5405	1.435e-61	227.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
ZZS3_k127_6268703_43	1120971.AUCA01000002_gene1490	1.019e-14	84.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,SoxE
ZZS3_k127_6268703_1	265072.Mfla_0490	4.822e-234	732.0	COG0477@1|root,COG2814@2|Bacteria,1QV32@1224|Proteobacteria,2VK3Z@28216|Betaproteobacteria,2KKFX@206350|Nitrosomonadales	206350|Nitrosomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_6268703_46	1122612.AUBA01000007_gene1020	9.598e-06	49.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,2TWNV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_6268703_4	667632.KB890164_gene1992	4.884e-173	562.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VMVP@28216|Betaproteobacteria,1KFG8@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
ZZS3_k127_6268703_33	395493.BegalDRAFT_3488	2.252e-45	180.0	COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,1S09X@1236|Gammaproteobacteria,46286@72273|Thiotrichales	72273|Thiotrichales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
ZZS3_k127_6268703_11	861299.J421_2669	4.389e-119	395.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
ZZS3_k127_6268703_12	1379270.AUXF01000004_gene3128	3.104e-114	378.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
ZZS3_k127_6268703_7	861299.J421_2667	1.229e-156	499.0	COG0022@1|root,COG0022@2|Bacteria,1ZTA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
ZZS3_k127_6268703_10	861299.J421_2666	8.05e-124	411.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_6268703_3	861299.J421_2662	5.861e-188	597.0	COG1249@1|root,COG1249@2|Bacteria,1ZT95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
ZZS3_k127_6268703_20	861299.J421_2661	9.978e-75	263.0	COG0321@1|root,COG0321@2|Bacteria,1ZTM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
ZZS3_k127_6268703_9	234267.Acid_0130	1.75e-129	428.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_6268703_19	1379270.AUXF01000004_gene3140	2.744e-80	281.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
ZZS3_k127_6268703_21	861299.J421_2657	2.304e-70	259.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
ZZS3_k127_6268703_22	266117.Rxyl_2116	1.792e-64	228.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
ZZS3_k127_6268703_0	1089553.Tph_c09340	1.336e-301	964.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS3_k127_6268703_8	379066.GAU_0736	1.906e-134	434.0	COG0825@1|root,COG0825@2|Bacteria,1ZSW6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
ZZS3_k127_6268703_15	861299.J421_2654	4.189e-97	328.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
ZZS3_k127_6268703_37	935567.JAES01000008_gene1989	3.145e-26	113.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_40	1123073.KB899243_gene729	2.366e-22	102.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,1SGZZ@1236|Gammaproteobacteria,1XC0C@135614|Xanthomonadales	135614|Xanthomonadales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
ZZS3_k127_6268703_5	379066.GAU_0734	3.83e-172	554.0	COG0143@1|root,COG0143@2|Bacteria,1ZTDB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (M)	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
ZZS3_k127_6268703_34	1242864.D187_008877	3.076e-44	173.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS3_k127_6268703_30	1487921.DP68_00775	1.377e-49	184.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,36E1V@31979|Clostridiaceae	186801|Clostridia	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ZZS3_k127_6268703_38	1340493.JNIF01000003_gene2938	1.197e-23	113.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6268703_35	861299.J421_2643	3.1e-39	157.0	COG1512@1|root,COG1512@2|Bacteria,1ZT1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
ZZS3_k127_6268703_36	383372.Rcas_3717	1.304e-36	149.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi,377EX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
ZZS3_k127_6268703_25	861299.J421_4004	2.098e-57	209.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS3_k127_6268703_14	861299.J421_2641	2.367e-103	353.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
ZZS3_k127_6268703_44	861299.J421_2636	1.466e-10	67.0	2FAWT@1|root,3433T@2|Bacteria,1ZTS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6471564_5	596154.Alide2_3373	5.694e-89	301.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2VJI6@28216|Betaproteobacteria,4AAH2@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
ZZS3_k127_6471564_0	1254432.SCE1572_36710	1.001e-245	768.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
ZZS3_k127_6471564_16	1227497.C491_01282	2.729e-33	141.0	COG4635@1|root,arCOG00524@2157|Archaea,2XWSS@28890|Euryarchaeota,23V70@183963|Halobacteria	183963|Halobacteria	C	COG4635 Flavodoxin	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
ZZS3_k127_6471564_6	404589.Anae109_3831	5.748e-85	293.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,42YGA@68525|delta/epsilon subdivisions,2X9TU@28221|Deltaproteobacteria,2Z21Y@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
ZZS3_k127_6471564_21	2850.Phatr48518	3.87e-07	56.0	COG0428@1|root,KOG2693@2759|Eukaryota	2759|Eukaryota	P	cellular zinc ion homeostasis	-	-	-	ko:K14714	ko04216,map04216	-	-	-	ko00000,ko00001,ko02000	2.A.5.4.15,2.A.5.4.8	-	-	Zip
ZZS3_k127_6471564_20	994479.GL877878_gene1177	5.444e-10	63.0	2B37N@1|root,31VVP@2|Bacteria,2GWAN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS3_k127_6471564_10	711393.AYRX01000083_gene4764	2.686e-49	183.0	2B37N@1|root,31VVP@2|Bacteria,2GWAN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
ZZS3_k127_6471564_12	1120954.ATXE01000001_gene1387	1.648e-40	155.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4DRK4@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
ZZS3_k127_6471564_7	479431.Namu_2462	2.798e-68	239.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4ES6H@85013|Frankiales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
ZZS3_k127_6471564_13	765420.OSCT_1598	3.018e-40	162.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
ZZS3_k127_6471564_17	246197.MXAN_5427	4.082e-19	93.0	COG1371@1|root,COG1371@2|Bacteria,1PXD3@1224|Proteobacteria,434G9@68525|delta/epsilon subdivisions,2WYTJ@28221|Deltaproteobacteria,2Z0KB@29|Myxococcales	28221|Deltaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
ZZS3_k127_6471564_1	246197.MXAN_5426	1.755e-168	544.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YZRQ@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
ZZS3_k127_6471564_14	335543.Sfum_4049	1.693e-38	150.0	COG1278@1|root,COG1544@1|root,COG1278@2|Bacteria,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,42TYD@68525|delta/epsilon subdivisions,2WQSG@28221|Deltaproteobacteria,2MQJ0@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
ZZS3_k127_6471564_11	1173028.ANKO01000158_gene4537	8.129e-42	160.0	COG1981@1|root,COG1981@2|Bacteria,1G18U@1117|Cyanobacteria,1H8D3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
ZZS3_k127_6471564_2	326427.Cagg_3368	5.42e-150	486.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi,377NT@32061|Chloroflexia	32061|Chloroflexia	H	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ZZS3_k127_6471564_19	861299.J421_1299	4.114e-17	92.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
ZZS3_k127_6471564_8	323261.Noc_2021	4.258e-66	248.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg
ZZS3_k127_6471564_4	1254432.SCE1572_36810	4.272e-98	329.0	COG0462@1|root,COG0462@2|Bacteria,1RCRN@1224|Proteobacteria,42QPH@68525|delta/epsilon subdivisions,2WMQV@28221|Deltaproteobacteria,2YU6H@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
ZZS3_k127_6471564_15	56107.Cylst_2967	5.987e-36	141.0	COG5502@1|root,COG5502@2|Bacteria,1G7AK@1117|Cyanobacteria,1HN9D@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
ZZS3_k127_6471564_9	1502851.FG93_03312	4.081e-58	211.0	COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,3JUQU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT,Pribosyltran
ZZS3_k127_6471564_3	1385517.N800_11360	3.533e-128	419.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,1RSI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
ZZS3_k127_6542337_2	234267.Acid_0349	9.538e-139	451.0	COG0438@1|root,COG1232@1|root,COG0438@2|Bacteria,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	tuaH	-	5.4.99.9	ko:K01854,ko:K07011	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,GLF,Glyco_trans_1_4,NAD_binding_8
ZZS3_k127_6542337_0	234267.Acid_0349	5.781e-228	716.0	COG0438@1|root,COG1232@1|root,COG0438@2|Bacteria,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	tuaH	-	5.4.99.9	ko:K01854,ko:K07011	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,GLF,Glyco_trans_1_4,NAD_binding_8
ZZS3_k127_6542337_1	1128421.JAGA01000003_gene2755	2.069e-155	502.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
ZZS3_k127_6542337_3	234267.Acid_0350	2.427e-131	429.0	COG2723@1|root,COG2723@2|Bacteria,3Y5XS@57723|Acidobacteria	57723|Acidobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6670893_16	379066.GAU_1894	4.8e-24	103.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ZZS3_k127_6670893_13	861299.J421_3464	7.135e-40	153.0	COG1610@1|root,COG1610@2|Bacteria,1ZTS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
ZZS3_k127_6670893_1	379066.GAU_1892	1.272e-157	532.0	COG1193@1|root,COG1193@2|Bacteria,1ZSWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
ZZS3_k127_6670893_5	518766.Rmar_0977	1.747e-86	310.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
ZZS3_k127_6670893_18	861299.J421_3461	8.596e-17	91.0	COG1579@1|root,COG1579@2|Bacteria,1ZU01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	-
ZZS3_k127_6670893_0	379066.GAU_1889	9.374e-160	523.0	COG0608@1|root,COG0608@2|Bacteria,1ZTGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ZZS3_k127_6670893_12	861299.J421_3458	1.228e-49	188.0	COG0742@1|root,COG0742@2|Bacteria,1ZTVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
ZZS3_k127_6670893_10	379066.GAU_1887	5.289e-60	214.0	COG0669@1|root,COG0669@2|Bacteria,1ZTTQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ZZS3_k127_6670893_4	1379270.AUXF01000006_gene74	9.792e-87	307.0	COG0280@1|root,COG0280@2|Bacteria,1ZT01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
ZZS3_k127_6670893_14	861299.J421_3455	1.43e-37	143.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
ZZS3_k127_6670893_17	756272.Plabr_3510	1.381e-21	100.0	COG2172@1|root,COG2172@2|Bacteria,2J0BZ@203682|Planctomycetes	203682|Planctomycetes	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
ZZS3_k127_6670893_3	861299.J421_3453	2.921e-105	366.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1ZSPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
ZZS3_k127_6670893_9	861299.J421_3452	7.924e-69	244.0	COG0030@1|root,COG0030@2|Bacteria,1ZT2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
ZZS3_k127_6670893_7	379066.GAU_1881	1.527e-70	244.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
ZZS3_k127_6670893_6	1168034.FH5T_12350	1.626e-76	272.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,2FRKB@200643|Bacteroidia	976|Bacteroidetes	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
ZZS3_k127_6670893_11	861299.J421_3450	9.84e-53	198.0	COG0847@1|root,COG0847@2|Bacteria,1ZTNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
ZZS3_k127_6670893_2	379066.GAU_1879	7.157e-107	357.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_6670893_8	379066.GAU_1878	1.064e-69	241.0	COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
ZZS3_k127_6670893_19	562970.Btus_2307	3.582e-15	79.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,278KV@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
ZZS3_k127_6670893_15	1307759.JOMJ01000003_gene2310	7.925e-26	108.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,2MBX1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
ZZS3_k127_6681027_21	861299.J421_3934	1.89e-32	126.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_6681027_30	981369.JQMJ01000003_gene7969	5.914e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,2NHZZ@228398|Streptacidiphilus	201174|Actinobacteria	K	ECF sigma factor	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_6681027_14	671143.DAMO_0102	5.593e-87	315.0	COG4772@1|root,COG4772@2|Bacteria,2NRIP@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
ZZS3_k127_6681027_16	365046.Rta_15000	2.208e-73	257.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2WFQP@28216|Betaproteobacteria,4ABHJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
ZZS3_k127_6681027_10	1379270.AUXF01000003_gene3456	1.796e-96	323.0	COG2086@1|root,COG2086@2|Bacteria,1ZT51@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
ZZS3_k127_6681027_4	861299.J421_3930	9.555e-122	407.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
ZZS3_k127_6681027_1	1242864.D187_010396	2.983e-178	575.0	COG0436@1|root,COG0436@2|Bacteria,1QHKS@1224|Proteobacteria,42Z0T@68525|delta/epsilon subdivisions,2WU4I@28221|Deltaproteobacteria,2YTVA@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
ZZS3_k127_6681027_28	1095769.CAHF01000022_gene214	1.034e-21	100.0	COG2020@1|root,COG2020@2|Bacteria,1PK67@1224|Proteobacteria,2WATQ@28216|Betaproteobacteria,4787Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6681027_0	1379698.RBG1_1C00001G0629	1.604e-214	679.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
ZZS3_k127_6681027_33	861299.J421_1152	2.353e-06	55.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
ZZS3_k127_6681027_32	561180.BIFGAL_04267	2.089e-07	64.0	COG0366@1|root,COG1404@1|root,COG5492@1|root,COG0366@2|Bacteria,COG1404@2|Bacteria,COG5492@2|Bacteria,2IAM2@201174|Actinobacteria,4CZYB@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial Ig-like domain 2	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CBM_25,SLH
ZZS3_k127_6681027_34	861299.J421_2463	7.653e-06	59.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,Big_3_5,ChW,He_PIG,LRR_5,Peptidase_S8,TIG
ZZS3_k127_6681027_22	1210884.HG799475_gene15276	8.843e-32	144.0	COG1572@1|root,COG2304@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.14.18.1,3.4.24.40	ko:K00505,ko:K01406,ko:K07004	ko00350,ko00950,ko00965,ko01100,ko01110,ko01503,ko04916,map00350,map00950,map00965,map01100,map01110,map01503,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,VCBS,VWA_2
ZZS3_k127_6681027_25	269799.Gmet_0933	3.318e-26	126.0	COG2304@1|root,COG2373@1|root,COG3391@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG3391@2|Bacteria,1QU09@1224|Proteobacteria	1224|Proteobacteria	M	regulator of chromosome condensation, RCC1	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Cadherin,He_PIG,RHS_repeat
ZZS3_k127_6681027_31	686340.Metal_3142	2.793e-17	97.0	COG0028@1|root,COG2911@1|root,COG0028@2|Bacteria,COG2911@2|Bacteria,1MZD7@1224|Proteobacteria,1T439@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6681027_17	861299.J421_2603	9.127e-67	230.0	COG0432@1|root,COG0432@2|Bacteria,1ZV8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
ZZS3_k127_6681027_7	204669.Acid345_2087	1.112e-105	350.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
ZZS3_k127_6681027_13	379066.GAU_1792	3.394e-88	299.0	COG0329@1|root,COG0329@2|Bacteria,1ZSM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ZZS3_k127_6681027_18	1340493.JNIF01000003_gene2769	5.697e-53	203.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
ZZS3_k127_6681027_6	204669.Acid345_2491	4.76e-106	359.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
ZZS3_k127_6681027_5	379066.GAU_1795	7.184e-109	373.0	COG0136@1|root,COG0136@2|Bacteria,1ZTBS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Semialdehyde dehydrogenase, NAD binding domain	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ZZS3_k127_6681027_15	204669.Acid345_1040	2.243e-85	294.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_6681027_2	861299.J421_1154	5.844e-177	569.0	COG2270@1|root,COG2270@2|Bacteria,1ZSZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
ZZS3_k127_6681027_11	1121015.N789_02130	6.926e-94	330.0	COG0457@1|root,COG0793@1|root,COG0457@2|Bacteria,COG0793@2|Bacteria,1PW54@1224|Proteobacteria,1SXHB@1236|Gammaproteobacteria,1X8XJ@135614|Xanthomonadales	135614|Xanthomonadales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6681027_12	316274.Haur_0016	9.972e-92	310.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
ZZS3_k127_6681027_8	861299.J421_4481	8.537e-103	341.0	COG0501@1|root,COG0501@2|Bacteria,1ZSNK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
ZZS3_k127_6681027_24	861299.J421_2998	1.01e-28	121.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
ZZS3_k127_6681027_9	485913.Krac_7853	7.864e-102	346.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
ZZS3_k127_6681027_27	56780.SYN_00289	2.441e-24	112.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,2MQKK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
ZZS3_k127_6681027_19	861299.J421_5587	9.215e-39	153.0	COG0746@1|root,COG0746@2|Bacteria,1ZU64@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ZZS3_k127_6681027_20	234267.Acid_6492	8.776e-33	132.0	COG1832@1|root,COG1832@2|Bacteria,3Y566@57723|Acidobacteria	57723|Acidobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
ZZS3_k127_6681027_23	1408422.JHYF01000009_gene2173	2.091e-30	132.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,36HJU@31979|Clostridiaceae	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
ZZS3_k127_6681027_26	861299.J421_3925	4.851e-26	113.0	COG0720@1|root,COG0720@2|Bacteria,1ZTRR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
ZZS3_k127_6681027_29	861299.J421_3923	1.856e-19	98.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6681027_3	861299.J421_3922	8.695e-130	422.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
ZZS3_k127_6863606_10	1120944.JONS01000060_gene274	9.31e-37	140.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4D574@85005|Actinomycetales	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
ZZS3_k127_6863606_4	1166018.FAES_2687	1.607e-113	381.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
ZZS3_k127_6863606_1	861299.J421_3598	4.379e-174	553.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
ZZS3_k127_6863606_0	861299.J421_3597	3.064e-175	559.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
ZZS3_k127_6863606_3	278963.ATWD01000001_gene3203	1.045e-126	422.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
ZZS3_k127_6863606_12	1379270.AUXF01000003_gene3865	2.831e-23	101.0	2FHQX@1|root,349IG@2|Bacteria,1ZU2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6863606_7	861299.J421_3592	2.588e-64	232.0	COG0613@1|root,COG0613@2|Bacteria,1ZTHM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
ZZS3_k127_6863606_16	283942.IL1461	0.0002477	48.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,2QFYF@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	Bacterial protein of unknown function (DUF899)	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS3_k127_6863606_15	1284352.AOIG01000009_gene1816	6.053e-07	55.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,26XH1@186822|Paenibacillaceae	91061|Bacilli	O	Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
ZZS3_k127_6863606_11	861299.J421_0461	6.014e-28	124.0	COG1028@1|root,COG1028@2|Bacteria,1ZTWE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_6863606_6	861299.J421_3591	1.411e-73	256.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
ZZS3_k127_6863606_9	379066.GAU_1988	3.025e-53	199.0	2AEWX@1|root,314UJ@2|Bacteria,1ZUPP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6863606_5	1305836.AXVE01000002_gene3278	5.954e-88	300.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26CZ6@186818|Planococcaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ZZS3_k127_6863606_8	1125863.JAFN01000001_gene1846	3.321e-54	198.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ZZS3_k127_6863606_2	379066.GAU_0686	8.986e-131	432.0	COG0438@1|root,COG0438@2|Bacteria,1ZUNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase Family 4	-	-	-	ko:K14335	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
ZZS3_k127_6863606_13	861299.J421_1604	4.184e-11	74.0	COG0392@1|root,COG0392@2|Bacteria,1ZSUQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS3_k127_6863606_14	1123322.KB904669_gene3548	2.097e-08	57.0	COG0662@1|root,COG0662@2|Bacteria,2IHNU@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_6949770_4	867903.ThesuDRAFT_00542	1.986e-127	411.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WCCR@538999|Clostridiales incertae sedis	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
ZZS3_k127_6949770_16	1236518.BAKP01000026_gene1675	1.231e-10	67.0	2DD50@1|root,2ZGIJ@2|Bacteria,4P8A2@976|Bacteroidetes,2FZIU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6949770_7	489825.LYNGBM3L_22540	1.33e-101	341.0	COG0615@1|root,COG0615@2|Bacteria,1G1YM@1117|Cyanobacteria,1HHMP@1150|Oscillatoriales	1117|Cyanobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
ZZS3_k127_6949770_11	1121939.L861_02505	8.966e-59	226.0	COG0367@1|root,COG0367@2|Bacteria,1P2JR@1224|Proteobacteria	1224|Proteobacteria	E	asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6949770_3	861299.J421_2757	9.594e-139	457.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
ZZS3_k127_6949770_10	869210.Marky_0415	1.259e-61	227.0	COG0668@1|root,COG0668@2|Bacteria,1WJII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
ZZS3_k127_6949770_5	1379270.AUXF01000004_gene3060	8.779e-118	389.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
ZZS3_k127_6949770_9	1379270.AUXF01000004_gene3061	8.136e-81	276.0	COG1842@1|root,COG1842@2|Bacteria,1ZT82@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
ZZS3_k127_6949770_12	861299.J421_2753	1.688e-38	153.0	2E9HN@1|root,333QR@2|Bacteria,1ZTU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6949770_1	1237149.C900_05550	6.706e-268	845.0	COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
ZZS3_k127_6949770_14	521098.Aaci_2380	9.172e-15	85.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
ZZS3_k127_6949770_0	861299.J421_2748	0.0	1417.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ZZS3_k127_6949770_15	756067.MicvaDRAFT_1602	2.207e-13	79.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
ZZS3_k127_6949770_17	592015.HMPREF1705_02157	2.753e-09	65.0	COG2110@1|root,COG2110@2|Bacteria,3TB5Z@508458|Synergistetes	508458|Synergistetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
ZZS3_k127_6949770_8	379066.GAU_0826	7.64e-100	340.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_6949770_2	1379270.AUXF01000004_gene3069	1.062e-152	505.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
ZZS3_k127_6949770_6	66429.JOFL01000012_gene3092	4.662e-109	362.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria	201174|Actinobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
ZZS3_k127_69721_27	682795.AciX8_1219	1.102e-68	238.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS3_k127_69721_18	1192034.CAP_6426	2.123e-90	306.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZAP@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
ZZS3_k127_69721_20	649638.Trad_1218	3.812e-84	295.0	COG4850@1|root,COG4850@2|Bacteria,1WMEC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
ZZS3_k127_69721_34	861299.J421_5665	7.028e-43	165.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_69721_36	640510.BC1001_5250	2.297e-39	154.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,1K202@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
ZZS3_k127_69721_43	1192124.LIG30_4165	3.052e-18	90.0	COG3794@1|root,COG3794@2|Bacteria,1MZHR@1224|Proteobacteria,2WFFZ@28216|Betaproteobacteria,1KI1J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
ZZS3_k127_69721_0	861299.J421_2847	0.0	1150.0	COG0209@1|root,COG0209@2|Bacteria,1ZSU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
ZZS3_k127_69721_29	886293.Sinac_5721	8.118e-56	204.0	COG0663@1|root,COG0663@2|Bacteria,2IZP3@203682|Planctomycetes	203682|Planctomycetes	S	isoleucine patch	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
ZZS3_k127_69721_28	861299.J421_2823	3.359e-64	244.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_69721_45	518766.Rmar_2301	4.765e-17	96.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_2301|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_69721_19	379066.GAU_0939	1.959e-88	318.0	COG0860@1|root,COG0860@2|Bacteria,1ZT6J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
ZZS3_k127_69721_16	1379270.AUXF01000004_gene2956	6.997e-94	321.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
ZZS3_k127_69721_17	706587.Desti_1505	1.38e-93	323.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
ZZS3_k127_69721_22	379066.GAU_0937	3.844e-83	294.0	COG1472@1|root,COG1472@2|Bacteria,1ZST8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3
ZZS3_k127_69721_15	861299.J421_2839	1.745e-94	323.0	COG2377@1|root,COG2377@2|Bacteria,1ZSZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
ZZS3_k127_69721_13	861299.J421_2838	4.435e-101	338.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
ZZS3_k127_69721_5	379066.GAU_0933	2.84e-176	570.0	COG0405@1|root,COG0405@2|Bacteria,1ZT0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
ZZS3_k127_69721_40	379066.GAU_0932	1.104e-21	104.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_69721_4	861299.J421_2834	2.045e-178	576.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
ZZS3_k127_69721_21	379066.GAU_0930	1.683e-83	284.0	COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
ZZS3_k127_69721_35	379066.GAU_0929	4.641e-42	164.0	COG0735@1|root,COG0735@2|Bacteria,1ZTN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ZZS3_k127_69721_7	215803.DB30_2054	1.01e-148	479.0	COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,2YYT4@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
ZZS3_k127_69721_11	583355.Caka_1487	7.102e-117	403.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_69721_31	861299.J421_0809	1.429e-53	192.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_69721_37	1340493.JNIF01000003_gene1493	1.022e-34	140.0	2E32R@1|root,32Y2Y@2|Bacteria,3Y5RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_69721_1	861299.J421_2825	4.716e-226	726.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
ZZS3_k127_69721_10	861299.J421_2824	4.359e-124	406.0	COG4948@1|root,COG4948@2|Bacteria,1ZSKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
ZZS3_k127_69721_23	861299.J421_2819	9.43e-82	283.0	COG0123@1|root,COG0123@2|Bacteria,1ZSKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
ZZS3_k127_69721_47	379066.GAU_0914	5.438e-07	57.0	2C3VP@1|root,2ZRAS@2|Bacteria,1ZU7P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_69721_41	861299.J421_2817	2.516e-20	94.0	2FC5K@1|root,3449E@2|Bacteria,1ZU4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_69721_24	1379270.AUXF01000002_gene1417	7.028e-78	274.0	COG3391@1|root,COG3391@2|Bacteria,1ZUF6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_69721_44	1123388.AQWU01000055_gene1501	9.447e-18	92.0	COG3824@1|root,COG3824@2|Bacteria,1WJSP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
ZZS3_k127_69721_2	379066.GAU_0909	9.782e-209	659.0	COG0423@1|root,COG0423@2|Bacteria,1ZT4P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
ZZS3_k127_69721_38	269799.Gmet_2816	6.947e-30	138.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
ZZS3_k127_69721_25	1379270.AUXF01000001_gene2066	5.09e-76	270.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
ZZS3_k127_69721_12	1379270.AUXF01000004_gene2993	7.185e-106	354.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
ZZS3_k127_69721_3	1379270.AUXF01000004_gene2994	2.375e-180	575.0	COG0104@1|root,COG0104@2|Bacteria,1ZSNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
ZZS3_k127_69721_9	1379270.AUXF01000004_gene3004	1.639e-124	408.0	COG2805@1|root,COG2805@2|Bacteria,1ZT2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
ZZS3_k127_69721_8	861299.J421_2799	5.86e-136	440.0	COG0180@1|root,COG0180@2|Bacteria,1ZT3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
ZZS3_k127_69721_26	1379270.AUXF01000004_gene3006	1.095e-68	246.0	COG0483@1|root,COG0483@2|Bacteria,1ZTQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ZZS3_k127_69721_46	1196323.ALKF01000144_gene1313	5.604e-10	68.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,4HI58@91061|Bacilli,26VIE@186822|Paenibacillaceae	91061|Bacilli	E	Formiminotransferase-cyclodeaminase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
ZZS3_k127_69721_14	861299.J421_2796	1.207e-98	328.0	COG0024@1|root,COG0024@2|Bacteria,1ZTC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
ZZS3_k127_69721_32	1379270.AUXF01000004_gene3011	4.243e-50	184.0	COG0563@1|root,COG0563@2|Bacteria,1ZTHC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
ZZS3_k127_69721_6	861299.J421_2794	3.046e-160	515.0	COG0201@1|root,COG0201@2|Bacteria,1ZSYZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
ZZS3_k127_69721_33	1379270.AUXF01000004_gene3013	1.116e-47	179.0	COG0200@1|root,COG0200@2|Bacteria,1ZTP0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
ZZS3_k127_69721_42	861299.J421_2792	2.046e-18	87.0	COG1841@1|root,COG1841@2|Bacteria,1ZU4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L30p/L7e	-	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
ZZS3_k127_69721_30	379066.GAU_0890	2.111e-54	193.0	COG0098@1|root,COG0098@2|Bacteria,1ZTHD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
ZZS3_k127_6982447_42	639283.Snov_4159	1.601e-28	119.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,2TTMA@28211|Alphaproteobacteria,3F0Z2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	ABC transporter	yehX	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
ZZS3_k127_6982447_17	661478.OP10G_1632	8.046e-73	256.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
ZZS3_k127_6982447_11	748247.AZKH_2968	4.624e-110	367.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
ZZS3_k127_6982447_15	1123237.Salmuc_00512	3.414e-96	330.0	COG1793@1|root,COG1793@2|Bacteria,1NTIR@1224|Proteobacteria,2VG1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
ZZS3_k127_6982447_41	1410620.SHLA_54c000050	2.035e-29	125.0	COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,2UC0X@28211|Alphaproteobacteria,4BFEB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Plasmid stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6982447_38	1408473.JHXO01000005_gene1511	7.534e-33	136.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,MerR_1
ZZS3_k127_6982447_6	469383.Cwoe_5866	4.829e-136	441.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
ZZS3_k127_6982447_47	1379270.AUXF01000003_gene3489	1.304e-06	60.0	294MB@1|root,2ZS0S@2|Bacteria,1ZU7M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6982447_9	1379270.AUXF01000002_gene1837	4.249e-114	378.0	COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Asparaginase	-	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
ZZS3_k127_6982447_48	1123277.KB893239_gene1240	4.834e-06	59.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
ZZS3_k127_6982447_29	861299.J421_3035	9.077e-48	176.0	COG0526@1|root,COG0526@2|Bacteria,1ZU4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
ZZS3_k127_6982447_5	861299.J421_2400	5.37e-144	466.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
ZZS3_k127_6982447_49	397278.JOJN01000015_gene3461	1.253e-05	56.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DPKW@85009|Propionibacteriales	201174|Actinobacteria	EU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
ZZS3_k127_6982447_14	313606.M23134_00391	1.349e-100	352.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47NMM@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
ZZS3_k127_6982447_23	661478.OP10G_2718	2.396e-56	208.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	AXE1,DLH
ZZS3_k127_6982447_26	861299.J421_1786	7.097e-54	201.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS3_k127_6982447_25	861299.J421_1786	1.69e-55	206.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
ZZS3_k127_6982447_18	1123508.JH636441_gene3316	3.256e-71	274.0	2E1DD@1|root,32WSP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6982447_13	1254432.SCE1572_47310	8.363e-102	342.0	COG1475@1|root,COG1475@2|Bacteria,1Q2AH@1224|Proteobacteria,437X8@68525|delta/epsilon subdivisions,2X9QN@28221|Deltaproteobacteria,2YUMN@29|Myxococcales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
ZZS3_k127_6982447_8	861299.J421_1230	2.536e-117	413.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1230|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
ZZS3_k127_6982447_36	378806.STAUR_0350	1.466e-33	134.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,4382M@68525|delta/epsilon subdivisions,2X3CP@28221|Deltaproteobacteria,2YVFV@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
ZZS3_k127_6982447_30	1192034.CAP_6020	4.264e-46	185.0	COG3832@1|root,COG3832@2|Bacteria,1RF9V@1224|Proteobacteria,4381A@68525|delta/epsilon subdivisions,2X9UT@28221|Deltaproteobacteria,2YV8A@29|Myxococcales	28221|Deltaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
ZZS3_k127_6982447_10	1254432.SCE1572_02795	2.936e-112	383.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ZZS3_k127_6982447_28	640511.BC1002_6116	1.893e-48	179.0	COG1853@1|root,COG1853@2|Bacteria,1PS6X@1224|Proteobacteria,2WA4Q@28216|Betaproteobacteria,1K77I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
ZZS3_k127_6982447_12	288000.BBta_7781	5.016e-102	341.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2U655@28211|Alphaproteobacteria,3K47Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
ZZS3_k127_6982447_51	1139996.OMQ_02373	8.066e-05	55.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,4HG39@91061|Bacilli,4AZVM@81852|Enterococcaceae	91061|Bacilli	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS3_k127_6982447_37	491915.Aflv_0680	3.302e-33	140.0	COG1876@1|root,COG1876@2|Bacteria,1V69M@1239|Firmicutes,4HI21@91061|Bacilli	91061|Bacilli	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	ycdD3	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,Peptidase_M15_4
ZZS3_k127_6982447_46	211165.AJLN01000066_gene4520	9.306e-10	69.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
ZZS3_k127_6982447_32	765911.Thivi_3403	2.238e-44	171.0	2E1BF@1|root,32WRB@2|Bacteria,1NAPP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6982447_35	313612.L8106_24545	5.958e-34	139.0	COG2032@1|root,COG2032@2|Bacteria,1G9Z6@1117|Cyanobacteria,1HD5U@1150|Oscillatoriales	1117|Cyanobacteria	P	Copper/zinc superoxide dismutase (SODC)	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
ZZS3_k127_6982447_22	472759.Nhal_3553	9.464e-58	212.0	COG2133@1|root,COG3386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
ZZS3_k127_6982447_1	861299.J421_4070	6.354e-243	765.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
ZZS3_k127_6982447_40	861299.J421_4072	5.739e-31	130.0	COG2010@1|root,COG2010@2|Bacteria,1ZU6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
ZZS3_k127_6982447_27	861299.J421_6034	1.139e-53	216.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,Guanylate_cyc,Trans_reg_C
ZZS3_k127_6982447_19	379066.GAU_0094	4.379e-67	259.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_6982447_44	383372.Rcas_0309	5.438e-19	91.0	2EJQK@1|root,33DFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6982447_31	1040983.AXAE01000028_gene3992	1.115e-45	177.0	2FBK1@1|root,343R7@2|Bacteria,1NY88@1224|Proteobacteria,2UTP6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_6982447_45	1218084.BBJK01000007_gene1070	8.709e-15	81.0	2AK9N@1|root,31B04@2|Bacteria,1PIBN@1224|Proteobacteria,2W6Z5@28216|Betaproteobacteria,1KDBZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
ZZS3_k127_6982447_39	756067.MicvaDRAFT_2703	2.469e-32	128.0	COG3153@1|root,COG3153@2|Bacteria,1G5GM@1117|Cyanobacteria,1HBEZ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
ZZS3_k127_6982447_34	1379270.AUXF01000007_gene862	4.231e-37	143.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
ZZS3_k127_6982447_0	1033738.CAEP01000080_gene567	7.382e-273	847.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,26EPU@186818|Planococcaceae	91061|Bacilli	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
ZZS3_k127_6982447_7	379066.GAU_3212	1.189e-128	427.0	COG0006@1|root,COG0006@2|Bacteria,1ZUGP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
ZZS3_k127_6982447_21	525904.Tter_0037	8.688e-59	220.0	COG0175@1|root,COG0175@2|Bacteria,2NPHM@2323|unclassified Bacteria	2|Bacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
ZZS3_k127_6982447_3	1382306.JNIM01000001_gene2462	3.166e-175	566.0	COG0155@1|root,COG0155@2|Bacteria,2G7ZA@200795|Chloroflexi	200795|Chloroflexi	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
ZZS3_k127_6982447_20	1304865.JAGF01000001_gene2025	6.765e-62	242.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4F0HX@85016|Cellulomonadaceae	201174|Actinobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cobA	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
ZZS3_k127_6982447_33	1234664.AMRO01000034_gene2267	2.936e-42	162.0	COG4538@1|root,COG4538@2|Bacteria,1V7Q1@1239|Firmicutes,4HJ77@91061|Bacilli,1WHB3@129337|Geobacillus	91061|Bacilli	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
ZZS3_k127_6982447_4	316067.Geob_0321	6.036e-159	515.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44,Glyco_hydro_cc,Laminin_G_3,PA14
ZZS3_k127_6982447_2	1379270.AUXF01000002_gene1363	1.815e-182	602.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_6982447_16	1337936.IJ00_23265	6.285e-77	274.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1HKGI@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
ZZS3_k127_6982447_24	861299.J421_3529	1.388e-55	208.0	COG0584@1|root,COG0584@2|Bacteria,1ZTMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS3_k127_7017557_1	861299.J421_4311	8.562e-72	273.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
ZZS3_k127_7017557_4	1286106.MPL1_02313	0.0003415	49.0	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
ZZS3_k127_7017557_3	1286106.MPL1_02313	5.486e-15	76.0	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
ZZS3_k127_7017557_0	861299.J421_1344	4.303e-92	305.0	COG0262@1|root,COG0262@2|Bacteria,1ZVA8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
ZZS3_k127_7017557_2	309807.SRU_0987	3.422e-23	102.0	COG1917@1|root,COG1917@2|Bacteria,4P9GY@976|Bacteroidetes,1FKCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ZZS3_k127_7067571_32	679926.Mpet_1268	7.432e-56	205.0	COG0647@1|root,arCOG04221@2157|Archaea,2XTCH@28890|Euryarchaeota	28890|Euryarchaeota	G	sugar phosphatases of the HAD superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
ZZS3_k127_7067571_41	1121920.AUAU01000004_gene598	3.718e-29	135.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
ZZS3_k127_7067571_35	926560.KE387023_gene3374	3.886e-49	180.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
ZZS3_k127_7067571_39	234267.Acid_1190	1.081e-36	147.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
ZZS3_k127_7067571_23	1500894.JQNN01000001_gene529	1.666e-75	272.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VZ36@28216|Betaproteobacteria,472UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
ZZS3_k127_7067571_7	929556.Solca_0522	1.149e-217	689.0	COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7067571_44	314278.NB231_16553	4.098e-26	123.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1WZVD@135613|Chromatiales	135613|Chromatiales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
ZZS3_k127_7067571_25	1123519.PSJM300_10640	3.298e-66	249.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1YZQQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
ZZS3_k127_7067571_0	243233.MCA2264	0.0	1198.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XDSC@135618|Methylococcales	135618|Methylococcales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
ZZS3_k127_7067571_31	1089549.AZUQ01000001_gene166	2.937e-58	210.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4EYD4@85014|Glycomycetales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
ZZS3_k127_7067571_19	861299.J421_4396	8.275e-104	344.0	arCOG09511@1|root,2Z9DH@2|Bacteria	2|Bacteria	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
ZZS3_k127_7067571_20	379066.GAU_2073	2.194e-92	314.0	COG0008@1|root,COG0008@2|Bacteria,1ZURR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
ZZS3_k127_7067571_26	1242864.D187_009656	4.114e-66	232.0	COG0652@1|root,COG0652@2|Bacteria,1PEZS@1224|Proteobacteria,435IG@68525|delta/epsilon subdivisions,2WZW4@28221|Deltaproteobacteria,2Z2VB@29|Myxococcales	28221|Deltaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
ZZS3_k127_7067571_11	861299.J421_3611	2.309e-156	507.0	COG1301@1|root,COG1301@2|Bacteria,1ZT91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
ZZS3_k127_7067571_17	1123248.KB893314_gene3296	4.637e-113	378.0	COG0176@1|root,COG0176@2|Bacteria,4NDWV@976|Bacteroidetes,1IRBI@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K00616,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
ZZS3_k127_7067571_5	518766.Rmar_0472	4.135e-253	801.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1FIXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
ZZS3_k127_7067571_38	251229.Chro_2396	2.217e-39	158.0	COG0607@1|root,COG0607@2|Bacteria,1G8N9@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ZZS3_k127_7067571_40	861299.J421_6331	8.248e-34	134.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
ZZS3_k127_7067571_3	1519464.HY22_13165	1.475e-319	1018.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,1FEWC@1090|Chlorobi	1090|Chlorobi	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
ZZS3_k127_7067571_53	66874.JOFS01000025_gene1286	4.671e-06	58.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
ZZS3_k127_7067571_13	246197.MXAN_7329	5.864e-137	462.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
ZZS3_k127_7067571_45	1123504.JQKD01000020_gene5637	3.21e-24	111.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2WGK0@28216|Betaproteobacteria,4ADYH@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
ZZS3_k127_7067571_9	379066.GAU_2857	4.696e-173	554.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
ZZS3_k127_7067571_6	1379270.AUXF01000001_gene2467	2.166e-225	724.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1ZT1A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
ZZS3_k127_7067571_33	82654.Pse7367_2890	8.167e-56	207.0	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,1H80J@1150|Oscillatoriales	1117|Cyanobacteria	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
ZZS3_k127_7067571_12	1379270.AUXF01000005_gene642	6.993e-148	495.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_7067571_42	861299.J421_0341	1.123e-28	125.0	COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ZZS3_k127_7067571_4	861299.J421_2650	5.052e-271	871.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_7067571_28	861299.J421_2648	1.551e-62	235.0	COG0521@1|root,COG0521@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like,SusD-like_2,SusD_RagB
ZZS3_k127_7067571_54	215803.DB30_3153	1.744e-05	56.0	28XFN@1|root,2ZJD7@2|Bacteria,1QSV2@1224|Proteobacteria,43E20@68525|delta/epsilon subdivisions,2X95Y@28221|Deltaproteobacteria,2Z23X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7067571_30	1121920.AUAU01000004_gene852	7.722e-61	231.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria	57723|Acidobacteria	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
ZZS3_k127_7067571_29	452637.Oter_2330	5.977e-61	228.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
ZZS3_k127_7067571_47	211165.AJLN01000087_gene2578	7.808e-12	70.0	COG3569@1|root,COG3569@2|Bacteria,1G2R6@1117|Cyanobacteria	1117|Cyanobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
ZZS3_k127_7067571_18	1183438.GKIL_3693	8.777e-112	378.0	COG3569@1|root,COG3569@2|Bacteria,1G2R6@1117|Cyanobacteria	1117|Cyanobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
ZZS3_k127_7067571_16	861299.J421_4533	4.249e-114	378.0	COG0506@1|root,COG0506@2|Bacteria,1ZT6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
ZZS3_k127_7067571_48	379066.GAU_2852	9.336e-11	72.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7067571_24	379066.GAU_2851	1.659e-70	249.0	COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
ZZS3_k127_7067571_36	1379270.AUXF01000001_gene2089	2.239e-45	166.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	ypjD	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	MazG
ZZS3_k127_7067571_27	592015.HMPREF1705_01539	4.038e-64	226.0	COG0693@1|root,COG0693@2|Bacteria,3TB17@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
ZZS3_k127_7067571_57	1330700.JQNC01000003_gene1007	0.0004561	52.0	2DVTT@1|root,33X4Y@2|Bacteria,1WKIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
ZZS3_k127_7067571_49	1379270.AUXF01000001_gene2507	7.143e-09	62.0	2FCBU@1|root,344FF@2|Bacteria,1ZU39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7067571_8	861299.J421_4478	2.524e-196	629.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
ZZS3_k127_7067571_56	1379698.RBG1_1C00001G0290	0.000307	45.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
ZZS3_k127_7067571_2	379066.GAU_2797	0.0	1028.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
ZZS3_k127_7067571_14	861299.J421_4449	1.212e-122	415.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_7067571_1	379066.GAU_2777	0.0	1039.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
ZZS3_k127_7067571_52	1209072.ALBT01000028_gene1213	3.76e-06	54.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1FGXU@10|Cellvibrio	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Hpt,Response_reg
ZZS3_k127_7067571_50	588932.JHOF01000018_gene1037	3.409e-08	63.0	COG1378@1|root,COG1378@2|Bacteria,1N9ZU@1224|Proteobacteria,2U7Z9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
ZZS3_k127_7067571_34	1379270.AUXF01000001_gene2561	1.104e-54	207.0	2EW3S@1|root,33PH0@2|Bacteria,1ZTQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7067571_15	1379270.AUXF01000003_gene3645	1.416e-120	407.0	COG2234@1|root,COG2234@2|Bacteria,1ZUHI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
ZZS3_k127_7067571_21	1382306.JNIM01000001_gene3763	2.623e-82	282.0	COG0300@1|root,COG0300@2|Bacteria,2G7XW@200795|Chloroflexi	200795|Chloroflexi	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_7067571_10	1382306.JNIM01000001_gene3764	1.648e-172	551.0	COG0277@1|root,COG0277@2|Bacteria,2G8B5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
ZZS3_k127_7067571_22	649638.Trad_2705	3.12e-82	283.0	COG0382@1|root,COG0546@1|root,COG0382@2|Bacteria,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,UbiA
ZZS3_k127_7067571_55	1382359.JIAL01000001_gene2720	0.0001711	54.0	COG1232@1|root,COG1232@2|Bacteria,3Y320@57723|Acidobacteria,2JHSJ@204432|Acidobacteriia	204432|Acidobacteriia	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
ZZS3_k127_7067571_37	402777.KB235903_gene2226	6.443e-43	171.0	2EDZR@1|root,337UJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7083579_21	204669.Acid345_2313	1.928e-08	64.0	2AZDP@1|root,31RMA@2|Bacteria,3Y4JB@57723|Acidobacteria,2JJ76@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
ZZS3_k127_7083579_3	379066.GAU_3744	9.271e-204	642.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
ZZS3_k127_7083579_15	1517416.IDAT_03410	2.349e-41	160.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,2QGJQ@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	MgtC family	mgtC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
ZZS3_k127_7083579_17	1144313.PMI10_00587	1.608e-34	141.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,2NVZM@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
ZZS3_k127_7083579_20	637389.Acaty_c2461	2.879e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,1Q9E2@1224|Proteobacteria,1TD5N@1236|Gammaproteobacteria,2NCC3@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
ZZS3_k127_7083579_10	379066.GAU_0376	2.363e-68	245.0	COG0845@1|root,COG0845@2|Bacteria,1ZUTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
ZZS3_k127_7083579_7	1379270.AUXF01000002_gene1712	1.011e-101	343.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_7083579_5	1379270.AUXF01000002_gene1713	3.843e-132	432.0	COG0842@1|root,COG0842@2|Bacteria,1ZTNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
ZZS3_k127_7083579_2	1210884.HG799463_gene10315	5.007e-243	770.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
ZZS3_k127_7083579_19	258533.BN977_04095	3.194e-30	123.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,2I5NY@201174|Actinobacteria,236BA@1762|Mycobacteriaceae	201174|Actinobacteria	KT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Guanylate_cyc,Response_reg
ZZS3_k127_7083579_16	1122218.KB893653_gene615	3.804e-35	145.0	COG0287@1|root,COG1187@1|root,COG0287@2|Bacteria,COG1187@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,1JR1J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM Prephenate dehydrogenase	tyrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
ZZS3_k127_7083579_6	1379270.AUXF01000006_gene108	1.287e-106	359.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1ZSNA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	cmk	-	2.5.1.19,2.7.4.25	ko:K00800,ko:K00945	ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230	M00022,M00052	R00158,R00512,R01665,R03460	RC00002,RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
ZZS3_k127_7083579_13	909613.UO65_0705	7.189e-44	169.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4E2KR@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
ZZS3_k127_7083579_0	379066.GAU_1789	1.555e-286	890.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
ZZS3_k127_7083579_1	1379270.AUXF01000006_gene112	2.222e-258	806.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
ZZS3_k127_7083579_4	290397.Adeh_0257	3.378e-140	465.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUGB@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.3.4.6,6.4.1.2	ko:K01941,ko:K01961	ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R00774,R04385	RC00040,RC00253,RC00367,RC00378	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS3_k127_7083579_9	1379270.AUXF01000006_gene114	9.005e-77	273.0	COG2265@1|root,COG2265@2|Bacteria,1ZSPC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
ZZS3_k127_7083579_18	379066.GAU_1780	2.995e-31	132.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
ZZS3_k127_7083579_11	1379270.AUXF01000006_gene117	2.894e-60	211.0	COG0102@1|root,COG0102@2|Bacteria,1ZTIS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
ZZS3_k127_7083579_12	1379270.AUXF01000006_gene118	9.372e-50	180.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
ZZS3_k127_7083579_8	1379270.AUXF01000006_gene119	1.239e-101	336.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
ZZS3_k127_7133930_9	379066.GAU_0585	1.818e-42	164.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ZZS3_k127_7133930_6	518766.Rmar_0192	3.827e-51	184.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
ZZS3_k127_7133930_3	861299.J421_2704	4.273e-79	270.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
ZZS3_k127_7133930_5	861299.J421_2705	9.6e-62	221.0	COG4221@1|root,COG4221@2|Bacteria,1ZTPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_7133930_13	935848.JAEN01000005_gene3738	9.628e-14	84.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2PUVF@265|Paracoccus	28211|Alphaproteobacteria	M	Peptidase family M23	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ZZS3_k127_7133930_10	861299.J421_2706	8.66e-20	97.0	2FCPE@1|root,344SN@2|Bacteria,1ZU2F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7133930_1	880073.Calab_3204	1.504e-160	524.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
ZZS3_k127_7133930_7	861299.J421_2711	3.037e-49	179.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
ZZS3_k127_7133930_8	861299.J421_2712	2.126e-46	175.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
ZZS3_k127_7133930_0	861299.J421_6044	0.0	1013.0	COG2192@1|root,COG2192@2|Bacteria,1ZUTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
ZZS3_k127_7133930_14	765913.ThidrDRAFT_4138	2.336e-12	74.0	COG2192@1|root,COG2192@2|Bacteria,1R3MX@1224|Proteobacteria,1T69R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7133930_12	861299.J421_6042	6.343e-15	76.0	2EGPU@1|root,31UHV@2|Bacteria,1ZV7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7133930_4	43989.cce_4083	3.159e-71	257.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,3KHHI@43988|Cyanothece	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
ZZS3_k127_7133930_15	68170.KL590470_gene11213	5.341e-09	68.0	COG3595@1|root,COG3595@2|Bacteria,2I8IR@201174|Actinobacteria,4E6FZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
ZZS3_k127_7133930_11	861299.J421_2713	4.446e-17	91.0	COG1719@1|root,COG1719@2|Bacteria,1ZU65@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7133930_2	379066.GAU_0790	4.462e-86	292.0	COG0272@1|root,COG0272@2|Bacteria,1ZT5Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
ZZS3_k127_7292701_4	935557.ATYB01000014_gene3340	2.94e-81	273.0	COG2746@1|root,COG2746@2|Bacteria,1NBKU@1224|Proteobacteria,2UKEP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
ZZS3_k127_7292701_8	1499968.TCA2_3513	1.189e-16	88.0	COG3829@1|root,COG3829@2|Bacteria,1VM08@1239|Firmicutes,4IU3X@91061|Bacilli,277IA@186822|Paenibacillaceae	91061|Bacilli	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7292701_7	1123368.AUIS01000013_gene813	3.059e-48	180.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria,2NDJ6@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
ZZS3_k127_7292701_2	861299.J421_3957	9.499e-127	415.0	COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
ZZS3_k127_7292701_1	861299.J421_3960	4.34e-138	450.0	COG0078@1|root,COG0078@2|Bacteria,1ZT4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS3_k127_7292701_6	861299.J421_1729	2.49e-66	246.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_7292701_3	861299.J421_1230	1.664e-92	337.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1230|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
ZZS3_k127_7292701_0	1379270.AUXF01000003_gene3408	1.637e-183	588.0	COG1220@1|root,COG1220@2|Bacteria,1ZSVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
ZZS3_k127_7292701_5	379066.GAU_2505	1.877e-74	255.0	COG5405@1|root,COG5405@2|Bacteria,1ZSVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
ZZS3_k127_7314585_2	1121013.P873_08950	4.549e-79	272.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
ZZS3_k127_7314585_1	861299.J421_4351	2.7e-101	351.0	COG0833@1|root,COG0833@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294,ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.2,2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
ZZS3_k127_7314585_0	234267.Acid_6439	3.004e-187	631.0	COG1752@1|root,COG1752@2|Bacteria,3Y6N9@57723|Acidobacteria	57723|Acidobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
ZZS3_k127_7314585_3	472759.Nhal_2847	2.556e-51	185.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria,1WWJ9@135613|Chromatiales	135613|Chromatiales	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
ZZS3_k127_7363415_1	105559.Nwat_2076	4.116e-21	97.0	2C85H@1|root,33H5Y@2|Bacteria,1NJ1W@1224|Proteobacteria,1SSCR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7363415_2	639030.JHVA01000001_gene3838	3.218e-16	88.0	2C4AD@1|root,337IV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7363415_0	639030.JHVA01000001_gene3837	4.694e-106	357.0	2C4AC@1|root,30014@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7367821_49	391008.Smal_0938	1.018e-33	130.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1SPFG@1236|Gammaproteobacteria,1X5R8@135614|Xanthomonadales	135614|Xanthomonadales	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
ZZS3_k127_7367821_26	1144275.COCOR_01063	7.295e-75	261.0	COG0596@1|root,COG0596@2|Bacteria,1QVBQ@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7367821_3	1232410.KI421413_gene663	1.032e-232	755.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,43SAV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ZZS3_k127_7367821_61	379066.GAU_1908	8.974e-05	52.0	COG5608@1|root,COG5608@2|Bacteria,1ZTWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
ZZS3_k127_7367821_13	861299.J421_2864	3.713e-115	391.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
ZZS3_k127_7367821_21	379066.GAU_0477	8.396e-88	299.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
ZZS3_k127_7367821_38	861299.J421_4427	9.238e-59	217.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim,DUF4432,DUF5107
ZZS3_k127_7367821_20	1210884.HG799463_gene9923	1.294e-88	298.0	COG1878@1|root,COG1878@2|Bacteria,2J1IQ@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
ZZS3_k127_7367821_7	861299.J421_4428	1.389e-161	518.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
ZZS3_k127_7367821_56	379066.GAU_3083	5.929e-14	83.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7367821_60	643562.Daes_1331	2.26e-05	53.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MAK8@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PAS modulated sigma54 specific transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
ZZS3_k127_7367821_44	313606.M23134_05224	5.112e-42	166.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ZZS3_k127_7367821_0	861299.J421_4433	0.0	1019.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7367821_1	518766.Rmar_0629	5.639e-256	824.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
ZZS3_k127_7367821_32	1380390.JIAT01000010_gene4322	2.588e-65	229.0	COG1795@1|root,COG1795@2|Bacteria	2|Bacteria	S	PFAM Formaldehyde-activating enzyme (Fae)	fae	-	4.2.1.147	ko:K10713	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R08058	RC01583,RC01795	ko00000,ko00001,ko01000	-	-	-	Fae
ZZS3_k127_7367821_23	420662.Mpe_A3259	1.162e-78	276.0	COG0373@1|root,COG0373@2|Bacteria,1MXX5@1224|Proteobacteria,2VK09@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methylene-tetrahydromethanopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Mpt_N
ZZS3_k127_7367821_35	1380390.JIAT01000010_gene4317	2.639e-61	227.0	COG2441@1|root,COG2441@2|Bacteria	2|Bacteria	C	CO2 hydration protein (ChpXY)	cupB	-	-	-	-	-	-	-	-	-	-	-	ChpXY
ZZS3_k127_7367821_27	671143.DAMO_0096	3.92e-74	263.0	COG2232@1|root,COG2232@2|Bacteria	2|Bacteria	V	ATP-grasp domain	-	-	3.5.4.27	ko:K01499,ko:K06913	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03464	RC01870	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
ZZS3_k127_7367821_31	1304874.JAFY01000002_gene382	3.468e-67	249.0	COG1029@1|root,COG1029@2|Bacteria,3TBWP@508458|Synergistetes	508458|Synergistetes	C	Molybdopterin oxidoreductase	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdopterin
ZZS3_k127_7367821_6	1380390.JIAT01000010_gene4326	2.343e-192	614.0	COG1229@1|root,COG1229@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase subunit A	fhcA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
ZZS3_k127_7367821_14	265072.Mfla_1664	6.466e-107	354.0	COG2037@1|root,COG2037@2|Bacteria,1MVSD@1224|Proteobacteria,2VJSP@28216|Betaproteobacteria,2KME8@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	-	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
ZZS3_k127_7367821_43	1380390.JIAT01000010_gene4328	1.296e-43	171.0	COG2218@1|root,COG2218@2|Bacteria	2|Bacteria	C	formylmethanofuran dehydrogenase activity	fhcC	GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
ZZS3_k127_7367821_16	1380390.JIAT01000010_gene4329	2.314e-101	339.0	COG3252@1|root,COG3252@2|Bacteria	2|Bacteria	H	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT	mch	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704	3.5.4.27	ko:K01499	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03464	RC01870	ko00000,ko00001,ko00002,ko01000	-	-	-	MCH
ZZS3_k127_7367821_54	880070.Cycma_0841	8.205e-17	90.0	COG3224@1|root,COG3224@2|Bacteria,4NT3E@976|Bacteroidetes,47VYH@768503|Cytophagia	976|Bacteroidetes	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
ZZS3_k127_7367821_55	641524.ADICYQ_4196	2.763e-16	88.0	COG3224@1|root,COG3224@2|Bacteria,4NT3E@976|Bacteroidetes,47VYH@768503|Cytophagia	976|Bacteroidetes	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
ZZS3_k127_7367821_19	1380390.JIAT01000010_gene4336	6.207e-90	308.0	COG0189@1|root,COG0189@2|Bacteria,2HXBM@201174|Actinobacteria	201174|Actinobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK,TrkA_C
ZZS3_k127_7367821_33	671143.DAMO_0463	1.227e-64	235.0	COG1767@1|root,COG1767@2|Bacteria	2|Bacteria	H	triphosphoribosyl-dephospho-CoA synthase activity	citG	-	2.4.2.52,2.7.7.61	ko:K05964,ko:K05966,ko:K13927,ko:K13930	ko02020,map02020	-	R09675,R10706	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG,CitX
ZZS3_k127_7367821_46	886293.Sinac_1233	3.546e-38	149.0	COG0720@1|root,COG0720@2|Bacteria,2IZMP@203682|Planctomycetes	203682|Planctomycetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
ZZS3_k127_7367821_48	1380390.JIAT01000010_gene4335	3.444e-36	151.0	COG1411@1|root,COG1411@2|Bacteria	2|Bacteria	C	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ZZS3_k127_7367821_36	1380390.JIAT01000010_gene4334	2.621e-60	221.0	COG1548@1|root,COG1548@2|Bacteria	2|Bacteria	GK	Hydantoinase/oxoprolinase	-	-	2.5.1.131	ko:K07072	ko00680,map00680	-	R11040	RC01372,RC03335	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_A
ZZS3_k127_7367821_51	1380390.JIAT01000010_gene4333	2.112e-32	136.0	COG2054@1|root,COG2054@2|Bacteria	2|Bacteria	-	-	-	-	1.13.11.81,2.7.4.31,4.1.2.25,5.1.99.8	ko:K01633,ko:K07144	ko00680,ko00790,ko01100,map00680,map00790,map01100	M00126,M00840	R03504,R11037,R11039,R11073	RC00002,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
ZZS3_k127_7367821_10	1454004.AW11_00304	1.62e-130	454.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,Response_reg
ZZS3_k127_7367821_45	1380390.JIAT01000010_gene4332	4.286e-39	155.0	COG1891@1|root,COG1891@2|Bacteria,2HKMX@201174|Actinobacteria	201174|Actinobacteria	S	lyase activity	-	-	4.2.3.153	ko:K09733	ko00680,map00680	-	R10935	RC03315	ko00000,ko00001,ko01000	-	-	-	4HFCP_synth
ZZS3_k127_7367821_24	472759.Nhal_1378	5.435e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
ZZS3_k127_7367821_42	671143.DAMO_2649	7.343e-47	171.0	COG2154@1|root,COG2154@2|Bacteria,2NQ7C@2323|unclassified Bacteria	2|Bacteria	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	3.5.4.33,4.2.1.96	ko:K01724,ko:K11991	ko00790,map00790	-	R04734,R10223	RC00477,RC01208	ko00000,ko00001,ko01000,ko03016,ko04147	-	-	-	Polyketide_cyc2,Pterin_4a
ZZS3_k127_7367821_8	1380390.JIAT01000010_gene4319	7.098e-154	500.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
ZZS3_k127_7367821_11	1123508.JH636447_gene7943	1.441e-128	427.0	COG0147@1|root,COG0147@2|Bacteria,2IXEN@203682|Planctomycetes	203682|Planctomycetes	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
ZZS3_k127_7367821_30	228410.NE0014	4.226e-70	244.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,371WE@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Glutamine amidotransferase class-I	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS3_k127_7367821_40	1380390.JIAT01000010_gene4330	8.792e-56	209.0	COG2457@1|root,COG2457@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF447)	-	-	-	ko:K09154	-	-	-	-	ko00000	-	-	-	DUF447
ZZS3_k127_7367821_25	1380390.JIAT01000010_gene4331	6.945e-76	269.0	COG1907@1|root,COG1907@2|Bacteria,2IGTW@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring glycosyl groups	-	-	2.4.2.54	ko:K06984	ko00790,map00790	-	R10337,R11102	-	ko00000,ko00001,ko01000	-	-	-	-
ZZS3_k127_7367821_4	595536.ADVE02000001_gene1885	1.02e-223	712.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,36XWG@31993|Methylocystaceae	28211|Alphaproteobacteria	G	PQQ-like domain	moxF	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
ZZS3_k127_7367821_29	1038866.KB902812_gene741	1.34e-71	253.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,3JVGF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
ZZS3_k127_7367821_57	1121939.L861_20725	5.257e-13	75.0	COG2010@1|root,COG2010@2|Bacteria,1RD7T@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c mono- and diheme variants	cycB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_7367821_47	1380394.JADL01000001_gene2398	1.084e-36	150.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U0C2@28211|Alphaproteobacteria,2JSP3@204441|Rhodospirillales	204441|Rhodospirillales	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
ZZS3_k127_7367821_18	926566.Terro_0376	1.728e-95	327.0	COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,3Y3TB@57723|Acidobacteria,2JKB3@204432|Acidobacteriia	204432|Acidobacteriia	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS3_k127_7367821_50	478741.JAFS01000001_gene2213	4.17e-33	135.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	ndh	-	1.6.99.3,1.8.5.2	ko:K03885,ko:K16937	ko00190,ko00920,ko01120,map00190,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxD,DoxX,Pyr_redox_2
ZZS3_k127_7367821_2	479434.Sthe_2440	4.524e-247	782.0	COG1505@1|root,COG1505@2|Bacteria,2GBNH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
ZZS3_k127_7367821_9	357808.RoseRS_1829	4.404e-141	456.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ZZS3_k127_7367821_59	1382304.JNIL01000001_gene2578	1.557e-08	57.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
ZZS3_k127_7367821_34	1415780.JPOG01000001_gene658	3.245e-63	235.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X5D2@135614|Xanthomonadales	135614|Xanthomonadales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
ZZS3_k127_7367821_58	1144305.PMI02_00488	1.429e-12	73.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,2K9V3@204457|Sphingomonadales	204457|Sphingomonadales	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH,PBP
ZZS3_k127_7367821_39	266117.Rxyl_0110	1.16e-58	213.0	COG2215@1|root,COG2215@2|Bacteria,2HRK4@201174|Actinobacteria,4CTM5@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7367821_5	401053.AciPR4_2014	1.297e-193	625.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
ZZS3_k127_7367821_37	224719.Abm4_1672	2.951e-60	214.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,23P0H@183925|Methanobacteria	183925|Methanobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ZZS3_k127_7367821_28	861299.J421_2433	1.068e-71	247.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
ZZS3_k127_7367821_17	864069.MicloDRAFT_00039570	3.422e-99	340.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2TUW3@28211|Alphaproteobacteria,1JRTP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
ZZS3_k127_7367821_41	378806.STAUR_2943	1.961e-53	205.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
ZZS3_k127_7367821_15	1379270.AUXF01000005_gene457	1.544e-104	349.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_7367821_22	215803.DB30_3562	1.823e-86	305.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42U6K@68525|delta/epsilon subdivisions,2WQ4K@28221|Deltaproteobacteria,2YZCG@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
ZZS3_k127_7367821_12	1278073.MYSTI_03750	5.984e-123	419.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_7367821_53	861299.J421_3995	5.858e-18	83.0	2DING@1|root,303QG@2|Bacteria,1ZV8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
ZZS3_k127_7368927_17	290397.Adeh_0180	5.091e-37	142.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WPB9@28221|Deltaproteobacteria,2Z2ZN@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
ZZS3_k127_7368927_20	521674.Plim_3975	5.878e-26	116.0	COG1385@1|root,COG1385@2|Bacteria,2IZRM@203682|Planctomycetes	203682|Planctomycetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
ZZS3_k127_7368927_12	861299.J421_3467	2.897e-47	184.0	COG2264@1|root,COG2264@2|Bacteria,1ZST2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
ZZS3_k127_7368927_3	861299.J421_3468	8.579e-135	438.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
ZZS3_k127_7368927_5	1379270.AUXF01000006_gene61	9.991e-117	385.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
ZZS3_k127_7368927_4	861299.J421_3470	1.281e-121	403.0	COG0635@1|root,COG0635@2|Bacteria,1ZSSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ZZS3_k127_7368927_8	243231.GSU2550	1.234e-68	246.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
ZZS3_k127_7368927_2	861299.J421_3472	7.004e-137	443.0	COG0536@1|root,COG0536@2|Bacteria,1ZSVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
ZZS3_k127_7368927_11	861299.J421_3473	4.272e-50	186.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
ZZS3_k127_7368927_27	1237149.C900_03963	1.268e-05	58.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
ZZS3_k127_7368927_6	861299.J421_3478	1.352e-105	356.0	COG2870@1|root,COG2870@2|Bacteria,1ZT0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
ZZS3_k127_7368927_19	367299.JOEE01000007_gene190	1.221e-33	151.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FHZF@85021|Intrasporangiaceae	201174|Actinobacteria	P	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PKD
ZZS3_k127_7368927_22	1288963.ADIS_1715	2.336e-19	104.0	COG0739@1|root,COG4932@1|root,COG0739@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K08642,ko:K20276,ko:K21471	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Gram_pos_anchor,Peptidase_M23
ZZS3_k127_7368927_15	1173024.KI912151_gene2103	9.195e-41	154.0	COG1145@1|root,32YX2@2|Bacteria,1GRAD@1117|Cyanobacteria	1117|Cyanobacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7368927_25	28229.ND2E_0283	2.25e-10	73.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2Q626@267889|Colwelliaceae	1236|Gammaproteobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD,Peptidase_S8
ZZS3_k127_7368927_18	479431.Namu_4457	2.172e-36	160.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ETCD@85013|Frankiales	201174|Actinobacteria	S	Laminin G domain	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
ZZS3_k127_7368927_7	518766.Rmar_0040	2.234e-98	330.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes	976|Bacteroidetes	J	Pfam Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
ZZS3_k127_7368927_24	391625.PPSIR1_21484	4.201e-18	88.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2YZ7J@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
ZZS3_k127_7368927_9	316274.Haur_0234	3.128e-62	228.0	COG0438@1|root,COG0438@2|Bacteria,2G7TE@200795|Chloroflexi,3750Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_7368927_14	926550.CLDAP_04560	1.476e-42	171.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_7368927_0	861299.J421_3479	1.589e-237	762.0	COG1596@1|root,COG1596@2|Bacteria,1ZUC0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
ZZS3_k127_7368927_16	861299.J421_0857	1.804e-39	163.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K16554,ko:K21473	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011,ko02000	8.A.3.1	-	-	GNVR,NLPC_P60,Peptidase_M23,Wzz
ZZS3_k127_7368927_26	1121406.JAEX01000016_gene1881	6.87e-10	70.0	COG0500@1|root,COG2226@2|Bacteria,1RF23@1224|Proteobacteria,42YRT@68525|delta/epsilon subdivisions,2WTIX@28221|Deltaproteobacteria,2MBVU@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Caenorhabditis protein of unknown function, DUF268	-	-	-	-	-	-	-	-	-	-	-	-	DUF268
ZZS3_k127_7368927_13	880072.Desac_1658	3.163e-45	177.0	COG4976@1|root,COG4976@2|Bacteria,1QZZ0@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ZZS3_k127_7368927_21	368408.Tpen_1717	8.462e-26	121.0	COG0438@1|root,arCOG01403@2157|Archaea,2XR0U@28889|Crenarchaeota	28889|Crenarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_7368927_10	1173025.GEI7407_2186	1.842e-60	228.0	COG2244@1|root,COG2244@2|Bacteria,1G3GP@1117|Cyanobacteria,1HAX2@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
ZZS3_k127_7368927_1	102232.GLO73106DRAFT_00033450	8.685e-148	473.0	COG2089@1|root,COG2089@2|Bacteria,1G78N@1117|Cyanobacteria	1117|Cyanobacteria	M	synthase	spsE	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
ZZS3_k127_7376993_1	1408254.T458_02370	7.3e-189	600.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,26SJC@186822|Paenibacillaceae	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
ZZS3_k127_7376993_4	861299.J421_3532	4.728e-47	178.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
ZZS3_k127_7376993_0	1379270.AUXF01000006_gene38	3.171e-207	670.0	COG1674@1|root,COG1674@2|Bacteria,1ZSPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
ZZS3_k127_7376993_5	861299.J421_3528	8.893e-25	111.0	COG0792@1|root,COG0792@2|Bacteria,1ZTWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
ZZS3_k127_7376993_2	1379270.AUXF01000006_gene42	2.421e-172	546.0	COG0468@1|root,COG0468@2|Bacteria,1ZT78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
ZZS3_k127_7376993_6	714313.LSA_10540	4.235e-08	62.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae	91061|Bacilli	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
ZZS3_k127_7376993_3	1267535.KB906767_gene5292	4.034e-85	288.0	COG0013@1|root,COG0013@2|Bacteria,3Y359@57723|Acidobacteria,2JIIR@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ZZS3_k127_7513337_1	861299.J421_3942	1.832e-126	413.0	COG1208@1|root,COG1208@2|Bacteria,1ZSYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ZZS3_k127_7513337_9	351160.RCIX363	1.379e-15	80.0	COG0662@1|root,COG1208@1|root,arCOG00663@2157|Archaea,arCOG03003@2157|Archaea,2XUID@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MannoseP_isomer,NTP_transferase
ZZS3_k127_7513337_5	1121920.AUAU01000007_gene513	8.223e-32	132.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	napG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
ZZS3_k127_7513337_2	1379270.AUXF01000003_gene3431	2.637e-125	439.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	2|Bacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS3_k127_7513337_6	497964.CfE428DRAFT_0787	7.44e-31	127.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
ZZS3_k127_7513337_7	379066.GAU_2487	3.984e-28	121.0	COG0712@1|root,COG0712@2|Bacteria,1ZTP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
ZZS3_k127_7513337_4	861299.J421_3945	2.004e-38	150.0	COG0711@1|root,COG0711@2|Bacteria,1ZTPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
ZZS3_k127_7513337_8	861299.J421_3946	6.706e-23	103.0	COG0636@1|root,COG0636@2|Bacteria,1ZU1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
ZZS3_k127_7513337_3	1379270.AUXF01000003_gene3427	2.885e-77	276.0	COG0356@1|root,COG0356@2|Bacteria,1ZSQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
ZZS3_k127_7513337_10	1379270.AUXF01000003_gene3425	1.054e-07	55.0	2DFBE@1|root,2ZR6K@2|Bacteria,1ZU7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
ZZS3_k127_7513337_0	861299.J421_3951	3.447e-129	421.0	COG0714@1|root,COG0714@2|Bacteria,1ZT5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
ZZS3_k127_7513337_12	1267535.KB906767_gene561	0.0003525	44.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
ZZS3_k127_7513337_11	1267535.KB906767_gene2627	9.213e-06	52.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
ZZS3_k127_7543501_0	861299.J421_1360	6.15e-139	459.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_7543501_1	1095769.CAHF01000006_gene1878	1.333e-29	135.0	COG3652@1|root,COG3652@2|Bacteria,1N6QU@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
ZZS3_k127_7543501_2	471854.Dfer_0268	1.097e-14	79.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
ZZS3_k127_7584382_3	1121406.JAEX01000001_gene84	4.996e-73	251.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2M9FP@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
ZZS3_k127_7584382_2	414684.RC1_3768	3.287e-96	327.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2U5PV@28211|Alphaproteobacteria,2JU2N@204441|Rhodospirillales	204441|Rhodospirillales	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
ZZS3_k127_7584382_0	1128421.JAGA01000003_gene3211	6.648e-201	637.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ZZS3_k127_7584382_1	489825.LYNGBM3L_52770	3.651e-108	356.0	COG1028@1|root,COG1028@2|Bacteria,1GBR3@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ZZS3_k127_7584382_4	1089551.KE386572_gene1281	1.734e-19	89.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2TRA6@28211|Alphaproteobacteria,4BQET@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	NeuB family	-	-	2.5.1.101,2.5.1.132,2.5.1.56,2.5.1.57	ko:K01654,ko:K05304,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,NeuB,SAF
ZZS3_k127_7603478_2	1192034.CAP_0301	4.14e-10	61.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,43B0B@68525|delta/epsilon subdivisions,2X6EF@28221|Deltaproteobacteria,2Z3AR@29|Myxococcales	28221|Deltaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ZZS3_k127_7603478_0	926550.CLDAP_18370	3.348e-131	424.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
ZZS3_k127_7603478_1	1131553.JIBI01000003_gene1710	2.637e-17	92.0	COG0223@1|root,COG0726@1|root,COG0223@2|Bacteria,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,372SU@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ZZS3_k127_7603478_6	861299.J421_5926	0.0004721	51.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
ZZS3_k127_7603478_4	316056.RPC_3315	8.115e-09	68.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,3JRHQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	MA20_36195	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
ZZS3_k127_7603478_5	247490.KSU1_C0982	4.669e-08	65.0	2E1K4@1|root,32WXM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7603478_3	102129.Lepto7375DRAFT_2940	5.114e-09	68.0	COG2232@1|root,COG2232@2|Bacteria,1G4QF@1117|Cyanobacteria	1117|Cyanobacteria	S	ATP-grasp fold domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7620452_5	457570.Nther_2188	2.844e-78	282.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ZZS3_k127_7620452_2	1254432.SCE1572_09415	6.32e-144	463.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
ZZS3_k127_7620452_13	85643.Tmz1t_3375	2.835e-05	52.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,2KUYQ@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg
ZZS3_k127_7620452_4	1254432.SCE1572_09420	9.93e-137	444.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,42SJI@68525|delta/epsilon subdivisions,2WPX2@28221|Deltaproteobacteria,2YV2D@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
ZZS3_k127_7620452_6	1125863.JAFN01000001_gene3143	5.433e-76	271.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2WKS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ZZS3_k127_7620452_11	159450.NH14_14850	3.57e-11	66.0	COG2879@1|root,COG2879@2|Bacteria,1N6TY@1224|Proteobacteria,2VW22@28216|Betaproteobacteria,1K9A1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
ZZS3_k127_7620452_0	861299.J421_3938	1.036e-288	902.0	COG1966@1|root,COG1966@2|Bacteria,1ZSWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
ZZS3_k127_7620452_8	1379698.RBG1_1C00001G0906	6.236e-58	215.0	COG1028@1|root,COG1028@2|Bacteria,2NP35@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_7620452_3	1379270.AUXF01000003_gene3443	1.727e-141	458.0	COG0473@1|root,COG0473@2|Bacteria,1ZTDX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ZZS3_k127_7620452_10	1123355.JHYO01000015_gene2017	3.378e-33	147.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2U2ZN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
ZZS3_k127_7620452_7	861299.J421_3936	2.858e-59	224.0	COG1409@1|root,COG1409@2|Bacteria,1ZTQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
ZZS3_k127_7620452_9	379066.GAU_2473	2.716e-45	172.0	2C421@1|root,33VAH@2|Bacteria,1ZTQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
ZZS3_k127_7620452_12	316279.Syncc9902_1656	3.528e-09	68.0	COG1266@1|root,COG1266@2|Bacteria,1G0ZJ@1117|Cyanobacteria,1GZ8P@1129|Synechococcus	1117|Cyanobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ZZS3_k127_7620452_1	861299.J421_3934	6.609e-170	541.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_7631135_38	1379270.AUXF01000002_gene1414	1.227e-22	104.0	COG0317@1|root,COG0317@2|Bacteria,1ZTKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
ZZS3_k127_7631135_17	379066.GAU_2757	4.037e-132	441.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	soxB	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4246,iECS88_1305.ECS88_4396,iLF82_1304.LF82_624	5_nucleotid_C,Metallophos
ZZS3_k127_7631135_28	1173025.GEI7407_3229	3.622e-37	156.0	COG2199@1|root,COG5000@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,COG5278@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales	1117|Cyanobacteria	T	GGDEF domain'	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9
ZZS3_k127_7631135_41	351607.Acel_1215	5.166e-15	83.0	COG5516@1|root,COG5516@2|Bacteria,2GKQZ@201174|Actinobacteria,4EWTU@85013|Frankiales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
ZZS3_k127_7631135_24	1379270.AUXF01000005_gene462	4.534e-82	295.0	COG0515@1|root,COG0515@2|Bacteria,1ZTB4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ZZS3_k127_7631135_30	861299.J421_1911	1.048e-30	124.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ZZS3_k127_7631135_33	1123229.AUBC01000001_gene1557	5.98e-25	108.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,3JZIK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
ZZS3_k127_7631135_5	861299.J421_3665	1.389e-240	757.0	COG1164@1|root,COG1164@2|Bacteria,1ZTDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
ZZS3_k127_7631135_34	997346.HMPREF9374_1821	6.292e-25	122.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,4IRFV@91061|Bacilli,27BU9@186824|Thermoactinomycetaceae	91061|Bacilli	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
ZZS3_k127_7631135_19	379066.GAU_0426	1.969e-107	361.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
ZZS3_k127_7631135_16	1329516.JPST01000003_gene1162	1.728e-134	449.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HA2U@91061|Bacilli,27CKY@186824|Thermoactinomycetaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
ZZS3_k127_7631135_25	1535287.JP74_11215	5.295e-79	276.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3N8FZ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	TOBE domain	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
ZZS3_k127_7631135_21	1174504.AJTN02000153_gene1010	4.014e-94	325.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4IQN0@91061|Bacilli,1ZRMA@1386|Bacillus	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
ZZS3_k127_7631135_12	861299.J421_0065	5.347e-144	491.0	COG2120@1|root,COG2120@2|Bacteria,1ZT6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
ZZS3_k127_7631135_39	861299.J421_2404	2.046e-22	110.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7631135_42	379066.GAU_0510	9.093e-13	75.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7631135_35	404589.Anae109_3805	7.699e-24	106.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
ZZS3_k127_7631135_22	861299.J421_2624	5.702e-94	319.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ZZS3_k127_7631135_7	1382359.JIAL01000001_gene96	5.614e-170	547.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria,2JM1F@204432|Acidobacteriia	204432|Acidobacteriia	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
ZZS3_k127_7631135_36	1156937.MFUM_390011	9.157e-24	104.0	COG3288@1|root,COG3288@2|Bacteria,46T7S@74201|Verrucomicrobia,37H24@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
ZZS3_k127_7631135_18	402777.KB235903_gene2188	8.063e-110	367.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
ZZS3_k127_7631135_47	1125699.HMPREF9194_01022	4.513e-08	66.0	COG1196@1|root,COG1196@2|Bacteria,2J663@203691|Spirochaetes	203691|Spirochaetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7631135_31	1121104.AQXH01000001_gene2067	6.779e-29	122.0	COG3216@1|root,COG3216@2|Bacteria	2|Bacteria	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
ZZS3_k127_7631135_2	379066.GAU_1367	5.128e-287	904.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1ZSSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
ZZS3_k127_7631135_26	1120965.AUBV01000008_gene1992	1.505e-60	222.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ZZS3_k127_7631135_8	861299.J421_1591	5.626e-162	527.0	COG0498@1|root,COG0498@2|Bacteria,1ZSVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_7631135_15	105559.Nwat_0941	3.282e-135	445.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RZ0N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
ZZS3_k127_7631135_32	1379270.AUXF01000001_gene2333	6.107e-27	114.0	COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
ZZS3_k127_7631135_29	552811.Dehly_1438	5.49e-35	138.0	2DNS7@1|root,32YWC@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
ZZS3_k127_7631135_4	1380394.JADL01000001_gene2789	4.771e-247	773.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
ZZS3_k127_7631135_0	1379270.AUXF01000005_gene635	4e-308	958.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
ZZS3_k127_7631135_6	379066.GAU_1365	2.976e-190	606.0	COG0297@1|root,COG0297@2|Bacteria,1ZUKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
ZZS3_k127_7631135_14	1303518.CCALI_02107	1.322e-137	457.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
ZZS3_k127_7631135_10	671143.DAMO_2883	3.528e-149	494.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
ZZS3_k127_7631135_49	1120970.AUBZ01000013_gene1833	0.0001077	51.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
ZZS3_k127_7631135_45	231434.JQJH01000001_gene1857	4.935e-12	76.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,1RG3J@1224|Proteobacteria,2U7QD@28211|Alphaproteobacteria,3NBV8@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
ZZS3_k127_7631135_13	357808.RoseRS_2741	2.643e-140	451.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi,375XY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
ZZS3_k127_7631135_11	357808.RoseRS_2742	1.282e-147	474.0	COG2957@1|root,COG2957@2|Bacteria,2GAHD@200795|Chloroflexi,37657@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
ZZS3_k127_7631135_23	246197.MXAN_4747	4.056e-92	323.0	COG3193@1|root,COG3193@2|Bacteria,1QX6Y@1224|Proteobacteria,43BZP@68525|delta/epsilon subdivisions,2X7AG@28221|Deltaproteobacteria,2YU0D@29|Myxococcales	28221|Deltaproteobacteria	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
ZZS3_k127_7631135_3	1297742.A176_02902	4.539e-268	858.0	COG4206@1|root,COG4206@2|Bacteria,1QXUW@1224|Proteobacteria,43C7J@68525|delta/epsilon subdivisions,2X7HV@28221|Deltaproteobacteria,2YU5W@29|Myxococcales	28221|Deltaproteobacteria	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
ZZS3_k127_7631135_20	518766.Rmar_1596	3.859e-94	318.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
ZZS3_k127_7631135_9	518766.Rmar_1595	2.685e-161	518.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
ZZS3_k127_7631135_1	518766.Rmar_1593	5.843e-301	941.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
ZZS3_k127_7631135_27	1379270.AUXF01000001_gene2634	2.161e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ZZS3_k127_7631135_40	861299.J421_4376	1.77e-15	85.0	2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7631135_37	861299.J421_4377	3.294e-23	114.0	COG3595@1|root,COG3595@2|Bacteria,1ZU53@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
ZZS3_k127_7873417_10	1499967.BAYZ01000073_gene2017	8.177e-06	57.0	COG1470@1|root,COG2885@1|root,COG1470@2|Bacteria,COG2885@2|Bacteria,2NPWP@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF4384,DUF4625,OmpA,PEGA
ZZS3_k127_7873417_9	28444.JODQ01000013_gene2919	3.469e-07	58.0	2DWH7@1|root,340B5@2|Bacteria,2IJBM@201174|Actinobacteria,4EPYY@85012|Streptosporangiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
ZZS3_k127_7873417_3	479434.Sthe_2325	1.115e-89	306.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ZZS3_k127_7873417_0	861299.J421_4355	9.212e-112	379.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7873417_5	861299.J421_4356	2.578e-77	270.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_7873417_4	861299.J421_4357	1.139e-80	295.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_7873417_7	861299.J421_4358	2.095e-62	224.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ZZS3_k127_7873417_8	257310.BB3383	1.929e-32	138.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2VJ64@28216|Betaproteobacteria,3T24A@506|Alcaligenaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
ZZS3_k127_7873417_6	1121920.AUAU01000013_gene1716	8.543e-71	264.0	COG4313@1|root,COG4313@2|Bacteria,3Y7K3@57723|Acidobacteria	57723|Acidobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7873417_1	926560.KE387028_gene161	3.6e-100	344.0	COG0428@1|root,COG0428@2|Bacteria,1WM75@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_7873417_2	266117.Rxyl_0083	2.931e-94	312.0	COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
ZZS3_k127_815376_3	861299.J421_4006	2.536e-93	321.0	COG3266@1|root,COG3266@2|Bacteria,1ZT0N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_815376_4	452637.Oter_3088	1.049e-76	262.0	COG3647@1|root,COG3647@2|Bacteria,46W76@74201|Verrucomicrobia,3K781@414999|Opitutae	414999|Opitutae	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
ZZS3_k127_815376_2	861299.J421_4331	3.545e-110	366.0	COG1234@1|root,COG1234@2|Bacteria,1ZTG7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
ZZS3_k127_815376_13	1349785.BAUG01000031_gene1812	2.576e-20	103.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
ZZS3_k127_815376_6	379066.GAU_0711	7.456e-71	254.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
ZZS3_k127_815376_8	1379270.AUXF01000001_gene2818	1.974e-58	213.0	COG0767@1|root,COG0767@2|Bacteria,1ZSUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
ZZS3_k127_815376_5	379066.GAU_0824	5.245e-75	273.0	COG1194@1|root,COG1194@2|Bacteria,1ZTNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
ZZS3_k127_815376_7	861299.J421_4103	3.858e-59	226.0	COG0515@1|root,COG5184@1|root,COG0515@2|Bacteria,COG5184@2|Bacteria,1ZUHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	DKLTZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RCC1
ZZS3_k127_815376_12	861299.J421_4333	8.162e-27	114.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
ZZS3_k127_815376_16	561175.KB894098_gene5255	9.73e-06	53.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,4EKB4@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ZZS3_k127_815376_14	875328.JDM601_1011	9.604e-19	97.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,23355@1762|Mycobacteriaceae	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
ZZS3_k127_815376_10	1379270.AUXF01000001_gene2675	1.114e-35	142.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
ZZS3_k127_815376_1	316274.Haur_4289	2.889e-209	666.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
ZZS3_k127_815376_11	861299.J421_2335	8.087e-30	123.0	COG0239@1|root,COG0239@2|Bacteria,1ZU3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
ZZS3_k127_815376_9	861299.J421_2336	1.456e-50	185.0	COG1993@1|root,COG1993@2|Bacteria	2|Bacteria	T	acr, cog1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
ZZS3_k127_815376_15	1123256.KB907925_gene1491	1.763e-14	79.0	COG3453@1|root,COG3453@2|Bacteria,1N919@1224|Proteobacteria,1SEMT@1236|Gammaproteobacteria,1X8A2@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
ZZS3_k127_815376_0	926549.KI421517_gene2964	2.123e-211	676.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
ZZS3_k127_81852_34	861299.J421_3227	2.958e-114	372.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
ZZS3_k127_81852_99	768066.HELO_2196	6.33e-29	121.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1XJ6M@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
ZZS3_k127_81852_79	1089550.ATTH01000001_gene1793	4.776e-48	181.0	COG0500@1|root,COG0500@2|Bacteria,4NFKM@976|Bacteroidetes,1FJ6K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
ZZS3_k127_81852_61	861299.J421_3229	2.369e-73	269.0	COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacillithiol biosynthesis BshC	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
ZZS3_k127_81852_11	234267.Acid_1531	2.188e-173	559.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
ZZS3_k127_81852_3	1379270.AUXF01000006_gene290	5.247e-219	695.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
ZZS3_k127_81852_55	861299.J421_3233	3.069e-80	283.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
ZZS3_k127_81852_104	861299.J421_2320	1.912e-22	111.0	COG4783@1|root,COG4783@2|Bacteria,1ZT4T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_21	1267535.KB906767_gene1182	7.606e-148	473.0	COG3186@1|root,COG3186@2|Bacteria,3Y3K5@57723|Acidobacteria,2JHN0@204432|Acidobacteriia	204432|Acidobacteriia	E	Biopterin-dependent aromatic amino acid hydroxylase	-	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
ZZS3_k127_81852_57	387093.SUN_1532	9.826e-77	267.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
ZZS3_k127_81852_35	251221.35214825	4.94e-111	385.0	COG2755@1|root,COG3055@1|root,COG2755@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,F5_F8_type_C,Flg_new,Kelch_6,Lipase_GDSL_2
ZZS3_k127_81852_39	1095769.CAHF01000010_gene1357	5.074e-104	348.0	COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,2VM6H@28216|Betaproteobacteria,475PA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ZZS3_k127_81852_23	1379270.AUXF01000006_gene287	4.536e-138	452.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
ZZS3_k127_81852_26	562970.Btus_1769	6.622e-134	441.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
ZZS3_k127_81852_87	861299.J421_3236	1.231e-42	164.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
ZZS3_k127_81852_42	404380.Gbem_0008	1.471e-99	340.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
ZZS3_k127_81852_82	861299.J421_3238	1.099e-45	169.0	COG0789@1|root,COG0789@2|Bacteria,1ZTSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
ZZS3_k127_81852_49	379066.GAU_1605	3.453e-90	303.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
ZZS3_k127_81852_66	1379270.AUXF01000006_gene281	4.744e-69	250.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
ZZS3_k127_81852_52	909663.KI867149_gene3387	1.043e-87	293.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MR44@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
ZZS3_k127_81852_111	397948.Cmaq_1977	2.477e-14	82.0	COG1254@1|root,arCOG01674@2157|Archaea,2XR8S@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
ZZS3_k127_81852_77	378806.STAUR_6057	3.814e-50	184.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2YY5P@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
ZZS3_k127_81852_115	866536.Belba_1153	3.085e-06	57.0	COG2956@1|root,COG2956@2|Bacteria,4PMKI@976|Bacteroidetes,47Y3R@768503|Cytophagia	976|Bacteroidetes	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_6,TPR_7,TPR_8
ZZS3_k127_81852_75	861299.J421_3244	9.933e-54	200.0	COG0253@1|root,COG0253@2|Bacteria,1ZU42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
ZZS3_k127_81852_36	1379698.RBG1_1C00001G0996	5.596e-109	357.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
ZZS3_k127_81852_58	1379698.RBG1_1C00001G0995	9.35e-76	282.0	COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
ZZS3_k127_81852_88	379066.GAU_1614	8.501e-40	160.0	COG0392@1|root,COG0392@2|Bacteria,1ZTX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ZZS3_k127_81852_108	1293048.CBMB010000003_gene863	2.55e-16	93.0	COG0726@1|root,arCOG02877@2157|Archaea,2XT5E@28890|Euryarchaeota,23SF0@183963|Halobacteria	183963|Halobacteria	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_93	192952.MM_2111	2.24e-33	134.0	COG0110@1|root,arCOG01848@2157|Archaea,2Y65M@28890|Euryarchaeota,2NAZ9@224756|Methanomicrobia	224756|Methanomicrobia	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
ZZS3_k127_81852_91	1382306.JNIM01000001_gene1504	1.388e-34	147.0	COG5653@1|root,COG5653@2|Bacteria,2G8SZ@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
ZZS3_k127_81852_69	379066.GAU_1615	4.686e-66	242.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_81852_94	379066.GAU_1615	1.125e-32	141.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_81852_41	861299.J421_3249	2.834e-100	352.0	COG0463@1|root,COG0463@2|Bacteria,1ZTEI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_81852_10	1379270.AUXF01000006_gene272	6.285e-180	585.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
ZZS3_k127_81852_32	861299.J421_3251	3.355e-120	400.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
ZZS3_k127_81852_97	379066.GAU_1619	3.407e-31	139.0	2F01D@1|root,33T57@2|Bacteria,1ZTGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_102	861299.J421_3253	1.205e-27	126.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
ZZS3_k127_81852_37	861299.J421_3254	3.198e-108	365.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
ZZS3_k127_81852_86	1379270.AUXF01000006_gene267	5.836e-45	173.0	COG1778@1|root,COG1778@2|Bacteria,1ZTTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
ZZS3_k127_81852_45	1379270.AUXF01000006_gene266	5.851e-95	321.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
ZZS3_k127_81852_1	861299.J421_3257	5.862e-261	814.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
ZZS3_k127_81852_64	861299.J421_3258	2.942e-71	248.0	COG1212@1|root,COG1212@2|Bacteria,1ZSRD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
ZZS3_k127_81852_63	429009.Adeg_1161	1.541e-71	246.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,42G1H@68295|Thermoanaerobacterales	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ZZS3_k127_81852_38	379066.GAU_0292	5.183e-105	346.0	COG1131@1|root,COG1131@2|Bacteria,1ZT45@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ZZS3_k127_81852_50	861299.J421_0236	6.97e-90	320.0	29YN3@1|root,30KHK@2|Bacteria,1ZT0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
ZZS3_k127_81852_31	861299.J421_3262	2.959e-122	400.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ZZS3_k127_81852_113	1348657.M622_05445	8.808e-08	65.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2VU5M@28216|Betaproteobacteria,2KYRQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
ZZS3_k127_81852_92	861299.J421_3263	2.17e-33	147.0	COG0586@1|root,COG0586@2|Bacteria,1ZTVI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
ZZS3_k127_81852_81	748280.NH8B_1083	5.751e-46	179.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,2KQVT@206351|Neisseriales	206351|Neisseriales	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
ZZS3_k127_81852_13	861299.J421_3265	1.135e-159	510.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
ZZS3_k127_81852_51	379066.GAU_1633	4.729e-88	299.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
ZZS3_k127_81852_15	1379270.AUXF01000006_gene256	3.396e-157	505.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
ZZS3_k127_81852_16	379066.GAU_1635	9.337e-156	503.0	COG0304@1|root,COG0304@2|Bacteria,1ZSPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ZZS3_k127_81852_103	861299.J421_3269	3.035e-27	112.0	COG0236@1|root,COG0236@2|Bacteria,1ZU0X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ZZS3_k127_81852_48	861299.J421_3270	3.647e-92	316.0	COG1028@1|root,COG1028@2|Bacteria,1ZT4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ZZS3_k127_81852_46	379066.GAU_1638	2.408e-94	323.0	COG0331@1|root,COG0331@2|Bacteria,1ZT40@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
ZZS3_k127_81852_29	861299.J421_3272	1.281e-126	413.0	COG0332@1|root,COG0332@2|Bacteria,1ZSP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ZZS3_k127_81852_43	861299.J421_3273	7.084e-99	333.0	COG0416@1|root,COG0416@2|Bacteria,1ZSN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
ZZS3_k127_81852_110	1120973.AQXL01000131_gene2116	8.051e-15	76.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,278KQ@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
ZZS3_k127_81852_101	861299.J421_3275	8.126e-28	118.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
ZZS3_k127_81852_76	379066.GAU_1643	1.871e-52	188.0	COG0105@1|root,COG0105@2|Bacteria,1ZTTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
ZZS3_k127_81852_25	379066.GAU_1645	8.339e-135	442.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
ZZS3_k127_81852_14	861299.J421_3279	5.506e-158	522.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
ZZS3_k127_81852_60	368407.Memar_0247	1.739e-73	258.0	COG0549@1|root,arCOG00863@2157|Archaea,2XTCB@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the carbamate kinase family	cpkA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ZZS3_k127_81852_96	118166.JH976537_gene2468	1.653e-31	143.0	COG1615@1|root,COG1615@2|Bacteria,1G05D@1117|Cyanobacteria,1H8E1@1150|Oscillatoriales	1117|Cyanobacteria	S	UPF0182 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0182
ZZS3_k127_81852_19	861299.J421_3281	8.547e-150	486.0	COG1109@1|root,COG1109@2|Bacteria,1ZSP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ZZS3_k127_81852_40	706587.Desti_2761	1.937e-101	353.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2MSIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
ZZS3_k127_81852_17	706587.Desti_2760	1.614e-155	509.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
ZZS3_k127_81852_2	861299.J421_3284	8.721e-228	724.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
ZZS3_k127_81852_98	861299.J421_3285	1.766e-29	128.0	COG0713@1|root,COG0713@2|Bacteria,1ZU00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
ZZS3_k127_81852_95	861299.J421_3286	6.802e-32	131.0	COG0839@1|root,COG0839@2|Bacteria,1ZTSA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
ZZS3_k127_81852_53	1379270.AUXF01000006_gene237	9.797e-82	279.0	COG1143@1|root,COG1143@2|Bacteria,1ZTHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
ZZS3_k127_81852_24	861299.J421_3288	4.424e-137	449.0	COG1005@1|root,COG1005@2|Bacteria,1ZTDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
ZZS3_k127_81852_9	861299.J421_3289	1.196e-183	588.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1ZTDW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
ZZS3_k127_81852_6	379066.GAU_1657	6.206e-199	630.0	COG1894@1|root,COG1894@2|Bacteria,1ZSQD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
ZZS3_k127_81852_59	1379270.AUXF01000006_gene233	5.841e-74	252.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
ZZS3_k127_81852_4	861299.J421_3292	1.205e-201	638.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
ZZS3_k127_81852_62	379066.GAU_1660	8.577e-72	247.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
ZZS3_k127_81852_47	861299.J421_3294	6.584e-94	313.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
ZZS3_k127_81852_89	1379270.AUXF01000006_gene229	4.447e-39	148.0	COG0838@1|root,COG0838@2|Bacteria,1ZTKK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
ZZS3_k127_81852_7	886293.Sinac_3438	1.392e-190	619.0	COG4122@1|root,COG4122@2|Bacteria,2IXSM@203682|Planctomycetes	203682|Planctomycetes	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_70	420324.KI911979_gene3245	2.774e-65	250.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_71	330214.NIDE3346	3.466e-65	233.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ZZS3_k127_81852_85	1082933.MEA186_09030	2.703e-45	174.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,2TX7N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
ZZS3_k127_81852_68	926569.ANT_11510	4.091e-67	250.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_117	429009.Adeg_1035	8.172e-05	47.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,24UMJ@186801|Clostridia,42HJV@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
ZZS3_k127_81852_116	429009.Adeg_1035	5.287e-05	50.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,24UMJ@186801|Clostridia,42HJV@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
ZZS3_k127_81852_109	296591.Bpro_2546	3.354e-16	86.0	COG4960@1|root,COG4960@2|Bacteria,1N7J0@1224|Proteobacteria,2VWBT@28216|Betaproteobacteria,4AFH6@80864|Comamonadaceae	28216|Betaproteobacteria	OU	Peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
ZZS3_k127_81852_114	1121422.AUMW01000024_gene247	1.706e-07	62.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,262QH@186807|Peptococcaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
ZZS3_k127_81852_80	234267.Acid_1409	2.324e-46	177.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
ZZS3_k127_81852_56	1267533.KB906738_gene2048	7.897e-80	285.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria,2JHJ6@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
ZZS3_k127_81852_112	641491.DND132_3035	2.46e-08	66.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
ZZS3_k127_81852_78	635013.TherJR_2810	3.954e-49	193.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,2616F@186807|Peptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
ZZS3_k127_81852_12	29581.BW37_01875	1.249e-166	536.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	U	type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
ZZS3_k127_81852_74	1158292.JPOE01000005_gene1225	1.104e-54	213.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2VJ80@28216|Betaproteobacteria,1KNGV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Type II secretion system (T2SS), protein F	tadB1	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
ZZS3_k127_81852_73	1215092.PA6_007_00130	1.303e-58	215.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1RTD3@1236|Gammaproteobacteria,1YGZH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein F	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
ZZS3_k127_81852_106	635013.TherJR_2806	4.813e-20	100.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,24QZ4@186801|Clostridia,2636A@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
ZZS3_k127_81852_27	1242864.D187_009124	6.335e-131	437.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
ZZS3_k127_81852_18	243231.GSU1815	6.905e-153	489.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	uxs	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ZZS3_k127_81852_44	861299.J421_3296	1.291e-97	321.0	COG0717@1|root,COG0717@2|Bacteria,1ZSN3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
ZZS3_k127_81852_5	861299.J421_1393	4.909e-200	645.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS3_k127_81852_8	518766.Rmar_0395	2.82e-187	606.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1FIJ4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
ZZS3_k127_81852_65	379066.GAU_0431	5.287e-70	257.0	COG5276@1|root,COG5276@2|Bacteria,1ZUNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
ZZS3_k127_81852_54	861299.J421_2036	4.412e-81	286.0	2EXQQ@1|root,33R07@2|Bacteria,1ZUK8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_81852_33	1128421.JAGA01000003_gene2922	3.262e-115	376.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
ZZS3_k127_81852_0	1267535.KB906767_gene402	0.0	1077.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria,2JIC4@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ZZS3_k127_81852_72	861299.J421_3300	1.251e-61	220.0	2CAZH@1|root,2Z7RU@2|Bacteria,1ZTQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
ZZS3_k127_81852_22	861299.J421_3301	2.184e-144	462.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
ZZS3_k127_81852_84	195250.CM001776_gene3084	2.678e-45	179.0	COG0219@1|root,COG0219@2|Bacteria,1G5TM@1117|Cyanobacteria,1H0BA@1129|Synechococcus	1117|Cyanobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
ZZS3_k127_81852_30	330214.NIDE1574	2.248e-123	406.0	COG2896@1|root,COG2896@2|Bacteria,3J0PB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
ZZS3_k127_81852_90	867903.ThesuDRAFT_00783	1.56e-38	150.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
ZZS3_k127_81852_83	861299.J421_3305	2.283e-45	167.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ZZS3_k127_81852_20	861299.J421_3306	9.952e-150	484.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
ZZS3_k127_81852_107	379066.GAU_1676	9.947e-18	88.0	COG1314@1|root,COG1314@2|Bacteria,1ZTZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
ZZS3_k127_81852_28	861299.J421_2550	3.499e-130	421.0	COG0266@1|root,COG0266@2|Bacteria,1ZUR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
ZZS3_k127_81852_67	1379270.AUXF01000006_gene214	1.958e-68	239.0	COG0149@1|root,COG0149@2|Bacteria,1ZSYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
ZZS3_k127_851621_46	1297617.JPJD01000021_gene1440	7.64e-21	99.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,269IV@186813|unclassified Clostridiales	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
ZZS3_k127_851621_6	861299.J421_3143	8.618e-188	603.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
ZZS3_k127_851621_9	861299.J421_3142	6.192e-163	520.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ZZS3_k127_851621_29	379066.GAU_1514	4.725e-68	235.0	COG2065@1|root,COG2065@2|Bacteria,1ZTHG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
ZZS3_k127_851621_17	861299.J421_0153	2.075e-118	398.0	COG4409@1|root,COG4409@2|Bacteria,1ZUI0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_851621_4	1255043.TVNIR_2748	2.014e-203	659.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,1T241@1236|Gammaproteobacteria,1X094@135613|Chromatiales	135613|Chromatiales	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
ZZS3_k127_851621_31	1000565.METUNv1_02913	3.701e-56	203.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KW1M@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
ZZS3_k127_851621_13	861299.J421_0076	3.276e-137	444.0	COG2041@1|root,COG2041@2|Bacteria,1ZTGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
ZZS3_k127_851621_57	622637.KE124774_gene2573	0.000737	48.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,36XJI@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
ZZS3_k127_851621_24	661478.OP10G_4235	3.777e-97	346.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Phosphodiest
ZZS3_k127_851621_25	1382359.JIAL01000001_gene1417	7.6e-92	319.0	COG0531@1|root,COG0531@2|Bacteria,3Y4PR@57723|Acidobacteria,2JJPB@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
ZZS3_k127_851621_10	1297742.A176_05941	4.43e-162	525.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ZZS3_k127_851621_1	518766.Rmar_2149	1.386e-271	856.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
ZZS3_k127_851621_19	1122622.ATWJ01000011_gene2286	5.028e-115	380.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4FFXK@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ZZS3_k127_851621_26	179408.Osc7112_2604	2.896e-87	299.0	COG1397@1|root,COG1397@2|Bacteria,1G30S@1117|Cyanobacteria,1HD71@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
ZZS3_k127_851621_41	1150626.PHAMO_30061	6.634e-32	134.0	COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,2TUD0@28211|Alphaproteobacteria,2JU7A@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
ZZS3_k127_851621_55	1550073.JROH01000009_gene1300	0.0001228	47.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
ZZS3_k127_851621_34	469383.Cwoe_5352	5.548e-44	167.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4CQ59@84995|Rubrobacteria	84995|Rubrobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
ZZS3_k127_851621_0	379066.GAU_1492	0.0	1163.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ZZS3_k127_851621_52	459349.CLOAM0172	2.416e-09	65.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
ZZS3_k127_851621_18	264732.Moth_2503	5.939e-118	414.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,42F9D@68295|Thermoanaerobacterales	186801|Clostridia	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
ZZS3_k127_851621_49	935948.KE386493_gene2419	2.189e-13	81.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,42GBN@68295|Thermoanaerobacterales	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
ZZS3_k127_851621_56	743721.Psesu_2020	0.000443	52.0	COG3391@1|root,COG3391@2|Bacteria,1R7H9@1224|Proteobacteria,1SGRP@1236|Gammaproteobacteria,1X57E@135614|Xanthomonadales	135614|Xanthomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
ZZS3_k127_851621_12	861299.J421_3134	9.975e-145	481.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
ZZS3_k127_851621_30	861299.J421_3133	3.633e-60	222.0	COG1120@1|root,COG1120@2|Bacteria,1ZTB9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
ZZS3_k127_851621_28	379066.GAU_0496	4.734e-69	248.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	2|Bacteria	P	FecCD transport family	btuC	-	3.6.3.34	ko:K02013,ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	FecCD
ZZS3_k127_851621_35	1379270.AUXF01000005_gene740	7.942e-42	166.0	COG0614@1|root,COG0614@2|Bacteria,1ZTIM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
ZZS3_k127_851621_40	379066.GAU_1486	1.417e-33	146.0	COG2010@1|root,COG2010@2|Bacteria,1ZT9T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_851621_33	1379270.AUXF01000005_gene738	4.012e-48	177.0	COG1259@1|root,COG1259@2|Bacteria,1ZTKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
ZZS3_k127_851621_7	886293.Sinac_1569	4.306e-178	569.0	COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes	203682|Planctomycetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
ZZS3_k127_851621_11	1125863.JAFN01000001_gene892	1.078e-147	501.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
ZZS3_k127_851621_21	1304284.L21TH_2295	7.679e-110	379.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
ZZS3_k127_851621_44	379066.GAU_1482	2.668e-23	106.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ZZS3_k127_851621_39	379066.GAU_1481	7.925e-34	143.0	COG3716@1|root,COG3716@2|Bacteria,1ZTJH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
ZZS3_k127_851621_45	861299.J421_3124	5.718e-23	112.0	COG3715@1|root,COG3715@2|Bacteria,1ZTVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
ZZS3_k127_851621_37	861299.J421_3123	3.517e-40	159.0	COG3444@1|root,COG3444@2|Bacteria,1ZTQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose subfamily IIB component	-	-	-	ko:K19507	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.19	-	-	PTSIIB_sorb
ZZS3_k127_851621_48	1379270.AUXF01000005_gene731	1.474e-16	84.0	COG2893@1|root,COG2893@2|Bacteria,1ZU41@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
ZZS3_k127_851621_16	379066.GAU_1477	7.887e-119	389.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
ZZS3_k127_851621_54	1111131.HMPREF1255_1391	1.786e-05	52.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4DQCT@85009|Propionibacteriales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
ZZS3_k127_851621_14	861299.J421_3119	1.63e-131	430.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ZZS3_k127_851621_43	861299.J421_3118	2.672e-26	116.0	COG0781@1|root,COG0781@2|Bacteria,1ZTRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
ZZS3_k127_851621_36	562970.Btus_1823	9.322e-41	155.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,279P7@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
ZZS3_k127_851621_5	861299.J421_3116	1.261e-190	601.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
ZZS3_k127_851621_32	861299.J421_3115	7.049e-51	188.0	COG0307@1|root,COG0307@2|Bacteria,1ZTQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
ZZS3_k127_851621_23	861299.J421_3114	4.301e-102	345.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
ZZS3_k127_851621_42	1379270.AUXF01000005_gene722	2.087e-27	125.0	2F30H@1|root,33VVT@2|Bacteria,1ZTRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_851621_22	861299.J421_3112	4.52e-105	357.0	COG0150@1|root,COG0150@2|Bacteria,1ZSQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ZZS3_k127_851621_20	861299.J421_3111	2.219e-113	376.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
ZZS3_k127_851621_3	1379270.AUXF01000005_gene719	7.747e-208	660.0	COG0018@1|root,COG0018@2|Bacteria,1ZT6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ZZS3_k127_851621_47	861299.J421_3109	9.116e-21	96.0	COG2331@1|root,COG2331@2|Bacteria,1ZU2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_851621_38	316067.Geob_3182	3.774e-38	152.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
ZZS3_k127_851621_2	861299.J421_3107	2.271e-220	698.0	COG1884@1|root,COG1884@2|Bacteria,1ZT5I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
ZZS3_k127_851621_15	945713.IALB_2637	4.631e-126	412.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
ZZS3_k127_851621_27	379066.GAU_1455	1.706e-82	302.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1ZSMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
ZZS3_k127_851621_50	1235793.C809_03126	8.959e-12	68.0	2DKBS@1|root,3094C@2|Bacteria,1U4EM@1239|Firmicutes,259F4@186801|Clostridia,27S9Z@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Late competence development protein ComFB	-	-	-	-	-	-	-	-	-	-	-	-	ComFB
ZZS3_k127_851621_8	861299.J421_3101	8.69e-169	541.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
ZZS3_k127_851621_51	767031.HMPREF9137_0082	1.001e-09	70.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,2FN33@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
ZZS3_k127_973304_4	861299.J421_1125	1.214e-116	379.0	COG0208@1|root,COG0208@2|Bacteria,1ZTAE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Fatty acid desaturase	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
ZZS3_k127_973304_9	1379270.AUXF01000004_gene3345	2.348e-38	150.0	COG0762@1|root,COG0762@2|Bacteria,1ZTUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
ZZS3_k127_973304_11	635013.TherJR_1860	2.625e-22	99.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
ZZS3_k127_973304_0	861299.J421_2471	0.0	1782.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1ZTEZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
ZZS3_k127_973304_1	379066.GAU_0558	3.603e-220	698.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
ZZS3_k127_973304_3	379066.GAU_0555	3.305e-161	516.0	COG1960@1|root,COG1960@2|Bacteria,1ZT6S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ZZS3_k127_973304_10	1234364.AMSF01000015_gene3322	4.15e-25	121.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1X310@135614|Xanthomonadales	135614|Xanthomonadales	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
ZZS3_k127_973304_12	1121405.dsmv_2300	3.268e-10	66.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ZZS3_k127_973304_5	1123057.P872_02555	5.455e-86	307.0	COG1404@1|root,COG1404@2|Bacteria,4NFFV@976|Bacteroidetes,47JYC@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ZZS3_k127_973304_2	1192034.CAP_8674	4.006e-206	667.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
ZZS3_k127_973304_7	42256.RradSPS_0204	1.677e-63	228.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
ZZS3_k127_973304_8	215803.DB30_4103	1.336e-45	173.0	COG0454@1|root,COG0456@2|Bacteria,1Q1ZZ@1224|Proteobacteria,42USA@68525|delta/epsilon subdivisions,2WQ2Q@28221|Deltaproteobacteria,2YVDC@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ZZS3_k127_973304_6	383372.Rcas_0232	2.165e-74	254.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
## 2942 queries scanned
## Total time (seconds): 239.68000531196594
## Rate: 12.27 q/s