## Sat Dec 13 17:09:19 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158188_bin.2.fa -m mmseqs --itype genome -o SRR25158188_bin.2 --output_dir /data/result/bins/wyx/egg/SRR25158188_bin.2 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158188_k127_1001792_5	1158606.I579_00975	1.299e-27	117.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,4B0J0@81852|Enterococcaceae	91061|Bacilli	S	Dak1_2	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158188_k127_1001792_6	1121946.AUAX01000007_gene2703	2.745e-20	101.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DEC1@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_1001792_1	1121472.AQWN01000002_gene2169	3.173e-52	201.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,261I8@186807|Peptococcaceae	186801|Clostridia	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158188_k127_1001792_0	1183438.GKIL_2112	8.491e-141	472.0	COG1200@1|root,COG1200@2|Bacteria,1G17H@1117|Cyanobacteria	1117|Cyanobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158188_k127_1001792_4	931627.MycrhDRAFT_6455	2.741e-29	126.0	COG1075@1|root,COG1075@2|Bacteria,2I3RN@201174|Actinobacteria,23FHD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158188_k127_1001792_3	469383.Cwoe_3700	2.523e-41	160.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158188_k127_1001792_2	469383.Cwoe_3699	2.086e-50	190.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158188_k127_1001792_7	1449976.KALB_5256	2.815e-19	99.0	2AS33@1|root,31HFS@2|Bacteria,2HSER@201174|Actinobacteria,4EDGH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1001792_8	1122939.ATUD01000004_gene3789	2.815e-16	78.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1002030_6	469383.Cwoe_3200	1.348e-94	317.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CPT1@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158188_k127_1002030_3	469383.Cwoe_3201	2.139e-138	459.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158188_k127_1002030_7	1380390.JIAT01000010_gene4854	5.623e-91	329.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CP5S@84995|Rubrobacteria	84995|Rubrobacteria	EF	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158188_k127_1002030_0	1125863.JAFN01000001_gene353	0.0	1104.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158188_k127_1002030_13	469383.Cwoe_3205	5.929e-44	171.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CTMJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
SRR25158188_k127_1002030_11	477974.Daud_1300	3.946e-53	206.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158188_k127_1002030_17	1380390.JIAT01000010_gene4851	1.872e-37	143.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1002030_12	1122939.ATUD01000005_gene2711	7.978e-49	183.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158188_k127_1002030_21	469383.Cwoe_3210	1.256e-23	109.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4CQGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158188_k127_1002030_8	867903.ThesuDRAFT_00338	5.923e-90	313.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WCE8@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158188_k127_1002030_5	1283283.ATXA01000003_gene1453	2.115e-101	340.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4ERGT@85013|Frankiales	201174|Actinobacteria	S	ATPase associated with various cellular activities	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158188_k127_1002030_20	43759.JNWK01000015_gene143	1.058e-25	122.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria	201174|Actinobacteria	J	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158188_k127_1002030_18	469383.Cwoe_3214	6.178e-37	161.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CQFZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158188_k127_1002030_25	929712.KI912613_gene3556	2.341e-13	76.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria,4CSUA@84995|Rubrobacteria	84995|Rubrobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1002030_14	1288484.APCS01000001_gene613	1.013e-43	163.0	COG1490@1|root,COG1490@2|Bacteria,1WJUX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158188_k127_1002030_22	929712.KI912613_gene3558	7.986e-22	102.0	COG0779@1|root,COG0779@2|Bacteria,2HPFT@201174|Actinobacteria,4CQU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158188_k127_1002030_2	469383.Cwoe_3219	9.123e-163	527.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158188_k127_1002030_26	706587.Desti_3723	5.829e-11	66.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
SRR25158188_k127_1002030_1	266117.Rxyl_1411	3.082e-214	683.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158188_k127_1002030_16	485913.Krac_9331	4.694e-39	152.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158188_k127_1002030_24	1476583.DEIPH_ctg003orf0003	1.601e-13	78.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158188_k127_1002030_23	204669.Acid345_4301	2.499e-19	93.0	COG1846@1|root,COG1846@2|Bacteria,3Y97P@57723|Acidobacteria,2JNFY@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158188_k127_1002030_27	234267.Acid_5182	1.173e-10	70.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158188_k127_1002030_4	1120971.AUCA01000009_gene2006	7.281e-129	424.0	COG0213@1|root,COG0295@1|root,COG0213@2|Bacteria,COG0295@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,278UM@186823|Alicyclobacillaceae	91061|Bacilli	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158188_k127_1002030_19	469383.Cwoe_3223	1.799e-26	112.0	COG0858@1|root,COG0858@2|Bacteria,2HPFC@201174|Actinobacteria,4CQTS@84995|Rubrobacteria	84995|Rubrobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158188_k127_1002030_9	469383.Cwoe_3224	8.314e-83	286.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158188_k127_1002030_15	191610.CATYP_04200	5.467e-42	165.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,22KXM@1653|Corynebacteriaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158188_k127_1002030_10	649831.L083_6798	1.799e-65	234.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4D8XR@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158188_k127_1002030_28	1172188.KB911827_gene4329	1.492e-06	58.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4FEK3@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_1006046_21	485916.Dtox_2364	1.426e-16	81.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,262DS@186807|Peptococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158188_k127_1006046_5	469383.Cwoe_3518	2.463e-93	318.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158188_k127_1006046_6	469383.Cwoe_3517	7.983e-86	297.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CQ0Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158188_k127_1006046_13	1283300.ATXB01000001_gene246	2.989e-53	197.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1XE51@135618|Methylococcales	135618|Methylococcales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158188_k127_1006046_4	1283299.AUKG01000002_gene4926	5.359e-94	318.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158188_k127_1006046_9	469383.Cwoe_3514	2.613e-64	227.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158188_k127_1006046_8	266117.Rxyl_1402	9.476e-72	250.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158188_k127_1006046_17	207559.Dde_1125	3.883e-31	132.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,2MHJR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158188_k127_1006046_15	1131730.BAVI_13049	1.013e-37	152.0	COG0491@1|root,COG0491@2|Bacteria,1TSU6@1239|Firmicutes,4HCB2@91061|Bacilli,1ZQUP@1386|Bacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_1006046_3	469383.Cwoe_3510	9.655e-103	346.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CPQ0@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158188_k127_1006046_14	1283299.AUKG01000002_gene4936	6.312e-42	177.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158188_k127_1006046_1	1122217.KB899574_gene2046	1.544e-119	394.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes	909932|Negativicutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158188_k127_1006046_0	469383.Cwoe_3494	1.07e-158	517.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158188_k127_1006046_24	1245475.ANAE01000079_gene3557	0.0001938	48.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,2GMWU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	GO:0001666,GO:0006082,GO:0006355,GO:0006629,GO:0006631,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016999,GO:0017144,GO:0019219,GO:0019222,GO:0019541,GO:0019679,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0036293,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0046459,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07110,ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
SRR25158188_k127_1006046_7	287986.DV20_37205	1.973e-82	293.0	COG1028@1|root,COG1028@2|Bacteria,2GWHQ@201174|Actinobacteria,4E2SN@85010|Pseudonocardiales	201174|Actinobacteria	IQ	short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158188_k127_1006046_11	1463926.JOCA01000002_gene5636	1.163e-61	229.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158188_k127_1006046_10	1463900.JOIX01000041_gene1984	3.868e-63	234.0	COG0302@1|root,COG0302@2|Bacteria,2H2JE@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase I	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydroI
SRR25158188_k127_1006046_16	937777.Deipe_2999	4.523e-36	146.0	COG0558@1|root,COG0558@2|Bacteria,1WIUS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SRR25158188_k127_1006046_2	526227.Mesil_2861	2.674e-119	398.0	COG0446@1|root,COG0446@2|Bacteria,1WM48@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C,Rieske
SRR25158188_k127_1006046_12	1380390.JIAT01000012_gene2898	4.646e-55	200.0	COG1595@1|root,COG1595@2|Bacteria,2IG3F@201174|Actinobacteria,4CT96@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1006046_20	1120934.KB894419_gene2081	3.568e-19	92.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4E5XU@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158188_k127_1006046_18	469383.Cwoe_0762	3.663e-30	128.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158188_k127_1006046_22	365044.Pnap_4548	1.126e-13	82.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2WEY0@28216|Betaproteobacteria,4AJBU@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
SRR25158188_k127_1021597_4	479431.Namu_4005	4.636e-12	74.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4ERRT@85013|Frankiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158188_k127_1021597_5	469371.Tbis_3289	1.362e-11	70.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4E3MR@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158188_k127_1021597_0	1380391.JIAS01000012_gene3972	4.865e-107	357.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,2JV02@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158188_k127_1021597_2	1112217.PPL19_01110	6.094e-61	219.0	COG0765@1|root,COG0765@2|Bacteria,1P3W6@1224|Proteobacteria,1SZ4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid ABC Transporter Permease	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158188_k127_1021597_3	330084.JNYZ01000009_gene6289	4.774e-36	147.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4DY10@85010|Pseudonocardiales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158188_k127_1021597_1	1206101.AZXC01000007_gene2590	8.443e-93	313.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158188_k127_1039426_3	1380390.JIAT01000009_gene542	9.865e-55	194.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CPMY@84995|Rubrobacteria	84995|Rubrobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158188_k127_1039426_2	42256.RradSPS_2112	9.156e-70	258.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_1039426_1	42256.RradSPS_2113	5.533e-71	265.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_1039426_0	42256.RradSPS_2114	2.666e-138	447.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158188_k127_1039426_6	1449346.JQMO01000003_gene3069	7.556e-06	53.0	2EMMT@1|root,33FA6@2|Bacteria,2I22G@201174|Actinobacteria,2M61F@2063|Kitasatospora	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158188_k127_1039426_4	1123024.AUII01000063_gene3178	1.059e-32	131.0	COG1846@1|root,COG1846@2|Bacteria,2INHB@201174|Actinobacteria,4E4N9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	HTH_27,MarR
SRR25158188_k127_1039426_5	1380390.JIAT01000009_gene545	9.122e-29	116.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158188_k127_1052778_6	100226.SCO6653	7.456e-32	128.0	COG0392@1|root,COG0392@2|Bacteria,2GP8H@201174|Actinobacteria	201174|Actinobacteria	H	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158188_k127_1052778_3	710686.Mycsm_01460	6.212e-88	299.0	COG2263@1|root,COG2263@2|Bacteria,2GNKR@201174|Actinobacteria	201174|Actinobacteria	J	DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_1052778_2	1386089.N865_02680	3.026e-107	360.0	COG0438@1|root,COG0438@2|Bacteria,2GYA2@201174|Actinobacteria,4FG9B@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_1052778_5	1123258.AQXZ01000018_gene744	5.626e-57	202.0	COG0720@1|root,COG0720@2|Bacteria,2II5D@201174|Actinobacteria	201174|Actinobacteria	H	6-pyruvoyl tetrahydropterin synthase	ptpS	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158188_k127_1052778_0	1386089.N865_02690	8.479e-151	483.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4FG3Z@85021|Intrasporangiaceae	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
SRR25158188_k127_1052778_7	1380346.JNIH01000042_gene5545	2.357e-27	119.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158188_k127_1052778_4	235985.BBPN01000008_gene4023	1.257e-81	276.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,2NJ2F@228398|Streptacidiphilus	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_1052778_1	981369.JQMJ01000004_gene4964	3.888e-127	412.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,2NKD9@228398|Streptacidiphilus	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158188_k127_106006_0	485913.Krac_6775	4.908e-155	494.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158188_k127_106006_3	880073.Calab_0272	1.702e-08	66.0	COG1649@1|root,COG3023@1|root,COG3391@1|root,COG4412@1|root,COG1649@2|Bacteria,COG3023@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.20,3.4.17.22,3.5.1.28	ko:K01187,ko:K01448,ko:K07752	ko00052,ko00500,ko01100,ko01503,map00052,map00500,map01100,map01503	M00727	R00028,R00801,R00802,R04112,R06087,R06088	RC00028,RC00049,RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	GH31	-	Amidase_2
SRR25158188_k127_106006_1	105425.BBPL01000074_gene3840	1.755e-61	216.0	COG2020@1|root,COG2020@2|Bacteria,2HUDA@201174|Actinobacteria,2NIQ9@228398|Streptacidiphilus	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158188_k127_106006_2	269799.Gmet_1919	2.618e-56	211.0	COG3437@1|root,COG3437@2|Bacteria,1RGGM@1224|Proteobacteria,42RTT@68525|delta/epsilon subdivisions,2WNA8@28221|Deltaproteobacteria,43TJF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response receiver-modulated cyclic diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
SRR25158188_k127_10681_1	929712.KI912613_gene2824	6.118e-64	228.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_10681_0	711393.AYRX01000010_gene2595	1.382e-233	737.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158188_k127_1074135_18	1122939.ATUD01000002_gene1242	6.088e-28	115.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CQHE@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158188_k127_1074135_0	1121380.JNIW01000026_gene279	5.061e-170	549.0	COG0277@1|root,COG0277@2|Bacteria,1WKVA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158188_k127_1074135_7	401526.TcarDRAFT_0978	1.206e-82	291.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H22D@909932|Negativicutes	909932|Negativicutes	G	fructose-1,6-bisphosphatase	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158188_k127_1074135_14	243230.DR_1514	7.222e-43	180.0	COG2074@1|root,COG2074@2|Bacteria,1WI2U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	2-phosphoglycerate kinase	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	ATP-cone
SRR25158188_k127_1074135_6	266117.Rxyl_1657	1.654e-86	305.0	COG2403@1|root,COG2403@2|Bacteria,2H3G5@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	-
SRR25158188_k127_1074135_4	266117.Rxyl_1658	3.953e-100	332.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158188_k127_1074135_3	1380390.JIAT01000016_gene5545	1.642e-104	353.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CQZ9@84995|Rubrobacteria	84995|Rubrobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158188_k127_1074135_13	1380390.JIAT01000016_gene5544	1.959e-43	166.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4CPW4@84995|Rubrobacteria	84995|Rubrobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158188_k127_1074135_16	309801.trd_A0384	2.482e-31	128.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi,27XU9@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158188_k127_1074135_11	929712.KI912613_gene4803	1.598e-47	178.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158188_k127_1074135_9	1128421.JAGA01000004_gene2555	1.177e-57	206.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15,2.7.7.42,2.7.7.89	ko:K00982,ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158188_k127_1074135_22	35754.JNYJ01000013_gene1079	0.0005502	47.0	2DRBI@1|root,33B4D@2|Bacteria,2HV33@201174|Actinobacteria,4DGKA@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1074135_12	997346.HMPREF9374_1966	4.203e-45	188.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,27C0N@186824|Thermoactinomycetaceae	91061|Bacilli	O	Subtilase family	vpr	GO:0005575,GO:0005576	3.4.21.110,3.4.21.96	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FIVAR,FlgD_ig,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5
SRR25158188_k127_1074135_1	469383.Cwoe_5282	2.3e-152	497.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158188_k127_1074135_5	1380390.JIAT01000007_gene5188	6.723e-93	334.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CPNK@84995|Rubrobacteria	84995|Rubrobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158188_k127_1074135_2	469383.Cwoe_3105	4.574e-117	385.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158188_k127_1074135_8	1380390.JIAT01000016_gene5642	1.681e-62	222.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQG8@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158188_k127_1074135_17	926550.CLDAP_06980	1.212e-29	124.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158188_k127_1074135_15	243230.DR_1710	2.097e-37	147.0	arCOG05253@1|root,31CTK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
SRR25158188_k127_1074135_10	1297742.A176_02012	4.456e-54	200.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2YWKM@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158188_k127_1074135_19	463191.SSEG_11130	3.174e-13	70.0	2EPJ6@1|root,33H5U@2|Bacteria,2IT42@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1077653_2	530564.Psta_4542	3.692e-22	97.0	COG0719@1|root,COG0719@2|Bacteria,2IY25@203682|Planctomycetes	203682|Planctomycetes	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158188_k127_1077653_3	485914.Hmuk_2625	0.000301	53.0	COG0695@1|root,arCOG02608@2157|Archaea,2XZBA@28890|Euryarchaeota,23WNV@183963|Halobacteria	183963|Halobacteria	O	COG0695 Glutaredoxin and related proteins	grx3	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
SRR25158188_k127_1077653_1	472759.Nhal_3675	3.127e-42	164.0	COG0500@1|root,COG0500@2|Bacteria,1R4KQ@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_1077653_0	243233.MCA1794	1.096e-245	770.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1XE4C@135618|Methylococcales	135618|Methylococcales	S	TIGRFAM ATP-binding cassette protein, ChvD family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158188_k127_1089574_1	469383.Cwoe_4527	1.698e-72	249.0	COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CR8U@84995|Rubrobacteria	84995|Rubrobacteria	G	BPG-independent PGAM N-terminus (iPGM_N)	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158188_k127_1089574_4	760568.Desku_0493	4.52e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_1089574_0	1283299.AUKG01000002_gene4126	3.659e-75	259.0	COG0639@1|root,COG0639@2|Bacteria,2HNQI@201174|Actinobacteria,4CPX1@84995|Rubrobacteria	84995|Rubrobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158188_k127_1089574_5	1122939.ATUD01000004_gene3699	5.611e-08	65.0	2AUAR@1|root,31JYD@2|Bacteria,2HNZF@201174|Actinobacteria,4CQ8Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1089574_3	469383.Cwoe_4519	1.048e-30	124.0	2AZMM@1|root,31RWC@2|Bacteria,2HTXT@201174|Actinobacteria,4CT9J@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
SRR25158188_k127_1089574_2	269084.syc0846_c	1.689e-57	219.0	COG1226@1|root,COG1226@2|Bacteria,1G0WK@1117|Cyanobacteria,1GYWE@1129|Synechococcus	1117|Cyanobacteria	P	potassium channel, VIC family protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158188_k127_1089574_6	1121035.AUCH01000006_gene630	1.658e-07	55.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KUXG@206389|Rhodocyclales	206389|Rhodocyclales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158188_k127_1094788_9	1380390.JIAT01000015_gene5716	8.671e-69	244.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158188_k127_1094788_5	645991.Sgly_3007	1.77e-100	342.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	degT1	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158188_k127_1094788_2	1380390.JIAT01000009_gene1705	2.95e-154	523.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4CP9E@84995|Rubrobacteria	84995|Rubrobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158188_k127_1094788_4	443218.AS9A_3744	8.08e-125	421.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,232S6@1762|Mycobacteriaceae	201174|Actinobacteria	L	DNA helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158188_k127_1094788_3	1380390.JIAT01000009_gene362	5.705e-131	441.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158188_k127_1094788_0	1380390.JIAT01000009_gene364	7.676e-244	767.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158188_k127_1094788_8	1380390.JIAT01000009_gene363	2.35e-70	245.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria	201174|Actinobacteria	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158188_k127_1094788_12	767817.Desgi_1949	1.47e-44	173.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158188_k127_1094788_11	463191.SSEG_09563	1.769e-52	201.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	tfdF	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158188_k127_1094788_6	1089550.ATTH01000001_gene1200	3.659e-88	298.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1FJ1X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158188_k127_1094788_7	469383.Cwoe_5533	1.255e-74	257.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4CQ9K@84995|Rubrobacteria	84995|Rubrobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158188_k127_1094788_10	525904.Tter_0038	1.722e-55	209.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158188_k127_1094788_1	469383.Cwoe_5535	1.072e-157	512.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4CRG2@84995|Rubrobacteria	84995|Rubrobacteria	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158188_k127_1094788_13	926549.KI421517_gene1992	1.202e-10	65.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
SRR25158188_k127_1101020_1	1095769.CAHF01000021_gene939	3.036e-73	255.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2VHA0@28216|Betaproteobacteria,477H5@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type sugar	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
SRR25158188_k127_1101020_0	290397.Adeh_3122	2.785e-90	317.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,43AKX@68525|delta/epsilon subdivisions,2X612@28221|Deltaproteobacteria,2Z33J@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158188_k127_1101020_2	1038859.AXAU01000018_gene6726	1.467e-41	171.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VFE8@28211|Alphaproteobacteria,3K63R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158188_k127_1102727_2	469383.Cwoe_4172	1.637e-81	276.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158188_k127_1102727_1	1123023.JIAI01000008_gene1501	1.252e-161	523.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4E0AT@85010|Pseudonocardiales	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
SRR25158188_k127_1102727_3	1298863.AUEP01000004_gene2264	5.868e-57	218.0	COG1832@1|root,COG1832@2|Bacteria,2HNAY@201174|Actinobacteria,4DVHA@85009|Propionibacteriales	201174|Actinobacteria	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
SRR25158188_k127_1102727_0	1298863.AUEP01000004_gene2263	1.828e-172	548.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DNVF@85009|Propionibacteriales	201174|Actinobacteria	E	O-acetylhomoserine	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158188_k127_1103987_2	1246626.BleG1_2540	9.646e-20	90.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
SRR25158188_k127_1103987_1	880072.Desac_0095	7.95e-140	453.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
SRR25158188_k127_1103987_0	981384.AEYW01000001_gene1562	4.82e-206	719.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
SRR25158188_k127_1110595_0	926550.CLDAP_20350	7.517e-93	324.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158188_k127_1110595_1	886293.Sinac_5284	5.347e-91	307.0	COG0396@1|root,COG0396@2|Bacteria,2IY5X@203682|Planctomycetes	203682|Planctomycetes	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158188_k127_1110595_4	1283299.AUKG01000001_gene1800	3.497e-11	68.0	COG1826@1|root,COG1826@2|Bacteria,2HRTJ@201174|Actinobacteria,4CTX0@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158188_k127_1110595_3	42256.RradSPS_1747	1.232e-35	145.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CP82@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158188_k127_1110595_2	574087.Acear_0510	1.076e-71	258.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3WB7T@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158188_k127_1117948_0	1464048.JNZS01000034_gene2628	3.352e-150	516.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158188_k127_1117948_6	1121430.JMLG01000002_gene1303	1.112e-15	84.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,262KE@186807|Peptococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158188_k127_1117948_3	1283299.AUKG01000001_gene1821	5.285e-47	174.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158188_k127_1117948_4	469383.Cwoe_5912	2.7e-30	126.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CQW6@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158188_k127_1117948_5	266117.Rxyl_0851	6.107e-29	128.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158188_k127_1117948_1	1254432.SCE1572_01045	3.469e-113	383.0	COG1222@1|root,COG1222@2|Bacteria,1R4U1@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,ClpS
SRR25158188_k127_1117948_2	635013.TherJR_2972	1.335e-77	270.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158188_k127_1118612_2	1380390.JIAT01000011_gene2341	2.837e-150	489.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4CPT3@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_1118612_3	1380390.JIAT01000011_gene2340	1.719e-113	387.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4CQE5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158188_k127_1118612_1	1380390.JIAT01000011_gene2339	3.442e-206	652.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4CPFN@84995|Rubrobacteria	84995|Rubrobacteria	C	ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158188_k127_1118612_4	518766.Rmar_2662	1.782e-98	336.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1FJ2X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158188_k127_1118612_5	1476876.JOJO01000003_gene5522	1.773e-94	323.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,SKI
SRR25158188_k127_1118612_0	1380390.JIAT01000011_gene2351	8.34e-264	822.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158188_k127_1124866_3	449447.MAE_04110	3.622e-07	52.0	COG1459@1|root,COG1459@2|Bacteria,1G164@1117|Cyanobacteria	1117|Cyanobacteria	U	bacterial type II secretion system protein F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158188_k127_1124866_2	370438.PTH_0557	3.096e-49	191.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia,261F2@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
SRR25158188_k127_1124866_1	1120934.KB894406_gene6070	8.447e-78	277.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,4E8PW@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_1124866_0	67373.JOBF01000013_gene4111	2.021e-106	353.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_1133469_0	469383.Cwoe_2195	6.241e-52	188.0	COG1309@1|root,COG1309@2|Bacteria,2GMNZ@201174|Actinobacteria,4CTR3@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158188_k127_1133469_1	65497.JODV01000013_gene2310	3.882e-41	169.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4DX5P@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158188_k127_1133469_2	1151122.AQYD01000007_gene1016	7.591e-23	112.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158188_k127_1140470_6	1380356.JNIK01000018_gene823	3.169e-26	123.0	COG0671@1|root,COG0671@2|Bacteria,2GVMI@201174|Actinobacteria	201174|Actinobacteria	I	phosphoesterase, PA-phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158188_k127_1140470_7	1038869.AXAN01000003_gene2825	5.931e-13	76.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,1K8TH@119060|Burkholderiaceae	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158188_k127_1140470_8	1380346.JNIH01000011_gene2742	3.789e-12	78.0	2DECE@1|root,2ZMCX@2|Bacteria,2GZS5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1140470_2	1449355.JQNR01000004_gene1668	6.395e-84	294.0	COG4280@1|root,COG4280@2|Bacteria,2GN58@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158188_k127_1140470_1	1463879.JOHP01000015_gene4482	2.668e-117	395.0	COG0477@1|root,COG2814@2|Bacteria,2I8TX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_1140470_5	1123320.KB889668_gene3322	3.3e-58	218.0	COG1277@1|root,COG1277@2|Bacteria,2GJ2R@201174|Actinobacteria	201174|Actinobacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158188_k127_1140470_0	1380347.JNII01000006_gene1624	3.222e-132	428.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4ESC8@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_1140470_4	670307.HYPDE_40378	9.698e-61	216.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2U7G6@28211|Alphaproteobacteria,3N8FM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158188_k127_1140470_3	1266914.ATUK01000003_gene1037	2.622e-65	225.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1WW2S@135613|Chromatiales	135613|Chromatiales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158188_k127_1140646_2	42256.RradSPS_0723	4.327e-85	292.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria,4CQFE@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase, class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158188_k127_1140646_0	469383.Cwoe_3561	1.668e-159	530.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CP5W@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158188_k127_1140646_3	1961.JOAK01000012_gene6100	1.013e-19	96.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158188_k127_1140646_1	1380390.JIAT01000010_gene4499	1.414e-110	368.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158188_k127_1140646_4	1380390.JIAT01000010_gene4501	1.493e-07	54.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CR4P@84995|Rubrobacteria	84995|Rubrobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158188_k127_1146781_0	644966.Tmar_0394	3.818e-229	720.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248QX@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158188_k127_1146781_8	2074.JNYD01000005_gene3269	3.28e-54	216.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4DXY4@85010|Pseudonocardiales	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158188_k127_1146781_9	1123023.JIAI01000016_gene3482	3.528e-39	166.0	COG4221@1|root,COG4221@2|Bacteria,2GQNJ@201174|Actinobacteria,4E2FN@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158188_k127_1146781_11	35754.JNYJ01000001_gene7311	1.246e-30	135.0	COG2050@1|root,COG2050@2|Bacteria,2HP0N@201174|Actinobacteria,4DKMF@85008|Micromonosporales	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158188_k127_1146781_10	378806.STAUR_1614	3.05e-37	155.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria,2YVI4@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_1146781_1	644966.Tmar_1329	1.339e-140	460.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,25BU2@186801|Clostridia,3WDV5@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_1146781_2	1111069.TCCBUS3UF1_860	1.539e-107	357.0	COG3173@1|root,COG3173@2|Bacteria,1WJ1R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158188_k127_1146781_12	1111069.TCCBUS3UF1_870	2.05e-15	91.0	2DRHM@1|root,33799@2|Bacteria,1WKGG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1146781_3	882083.SacmaDRAFT_2086	7.22e-98	328.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4E15A@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158188_k127_1146781_4	1122182.KB903814_gene3182	1.033e-81	287.0	COG1680@1|root,COG1680@2|Bacteria,2IG0Z@201174|Actinobacteria,4DDG9@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_1146781_5	1120936.KB907208_gene1218	2.184e-79	272.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4EN3G@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158188_k127_1146781_6	323097.Nham_0355	2.327e-71	259.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,3JSYB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter	MA20_18600	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158188_k127_1146781_7	1297863.APJF01000017_gene4397	3.536e-64	241.0	COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,2TVKT@28211|Alphaproteobacteria,3JSJG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_18605	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158188_k127_1159425_5	469383.Cwoe_5380	1.617e-64	233.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria,4CSXA@84995|Rubrobacteria	84995|Rubrobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158188_k127_1159425_3	469383.Cwoe_5381	5.156e-76	267.0	COG0745@1|root,COG0745@2|Bacteria,2IDQ0@201174|Actinobacteria,4CT58@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_1159425_1	929712.KI912613_gene1090	3.063e-111	373.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria,4CRZY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1159425_2	469383.Cwoe_4746	3.604e-110	369.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158188_k127_1159425_6	1380390.JIAT01000010_gene4220	1.065e-52	203.0	COG0515@1|root,COG0515@2|Bacteria,2HFRY@201174|Actinobacteria,4CRYK@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158188_k127_1159425_8	1122609.AUGT01000013_gene4123	3.68e-05	49.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4DP1A@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158188_k127_1159425_4	1192034.CAP_4742	2.638e-73	261.0	COG4403@1|root,COG4403@2|Bacteria,1PR3F@1224|Proteobacteria	1224|Proteobacteria	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158188_k127_1159425_0	1382306.JNIM01000001_gene2738	2.066e-113	373.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_1175063_4	351607.Acel_0553	9.036e-76	266.0	COG1175@1|root,COG1175@2|Bacteria,2GX5P@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17330	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR25158188_k127_1175063_2	390989.JOEG01000001_gene5408	2.091e-79	273.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4DBTC@85008|Micromonosporales	201174|Actinobacteria	G	ABC-type sugar transport system, permease component	dasC	-	-	ko:K17331	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR25158188_k127_1175063_3	1227454.C446_01021	5.733e-76	278.0	COG1874@1|root,arCOG04085@2157|Archaea,2XSU6@28890|Euryarchaeota,23UX4@183963|Halobacteria	183963|Halobacteria	G	COG1874 Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1175063_5	645465.ACUR01000242_gene6122	3.986e-72	266.0	COG2103@1|root,COG2103@2|Bacteria,2GN0K@201174|Actinobacteria	201174|Actinobacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158188_k127_1175063_1	1380390.JIAT01000009_gene1217	1.725e-80	300.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CRGD@84995|Rubrobacteria	84995|Rubrobacteria	G	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158188_k127_1175063_0	309801.trd_A0706	1.525e-89	309.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,27XY2@189775|Thermomicrobia	189775|Thermomicrobia	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158188_k127_119978_2	596152.DesU5LDRAFT_2310	1.097e-14	79.0	COG2199@1|root,COG3706@2|Bacteria,1RKZZ@1224|Proteobacteria,42T4R@68525|delta/epsilon subdivisions,2WPMG@28221|Deltaproteobacteria,2M8GV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158188_k127_119978_0	266117.Rxyl_1072	1.753e-93	322.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158188_k127_119978_1	867903.ThesuDRAFT_02358	1.366e-37	146.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3WDHP@538999|Clostridiales incertae sedis	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158188_k127_12064_0	1380390.JIAT01000009_gene365	2.239e-87	302.0	COG0438@1|root,COG0438@2|Bacteria,2HPUM@201174|Actinobacteria,4CR8J@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158188_k127_12064_1	1089545.KB913037_gene479	9.841e-26	112.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DYVZ@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_12064_2	1283299.AUKG01000002_gene4201	1.235e-09	61.0	COG1314@1|root,COG1314@2|Bacteria,2HP6M@201174|Actinobacteria,4CQIR@84995|Rubrobacteria	84995|Rubrobacteria	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
SRR25158188_k127_120741_0	1380390.JIAT01000009_gene1592	3.407e-46	186.0	COG2199@1|root,COG5000@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,2IA4H@201174|Actinobacteria,4CP5Q@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
SRR25158188_k127_120741_1	1380390.JIAT01000013_gene247	7.518e-41	159.0	COG0745@1|root,COG0745@2|Bacteria	1380390.JIAT01000013_gene247|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_120741_2	1279009.ADICEAN_00724	9.892e-05	51.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
SRR25158188_k127_12262_3	1105031.HMPREF1141_0814	1.243e-12	70.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,25B0S@186801|Clostridia,36WE2@31979|Clostridiaceae	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158188_k127_12262_2	338963.Pcar_0333	5.808e-38	153.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,42WFT@68525|delta/epsilon subdivisions,2WRC3@28221|Deltaproteobacteria,43V9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158188_k127_12262_1	1116232.AHBF01000116_gene4468	9.954e-51	196.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	ssuA_3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158188_k127_12262_0	882083.SacmaDRAFT_2713	2.17e-109	359.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,4E9GC@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158188_k127_1228004_1	1122939.ATUD01000019_gene1528	4.165e-159	512.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158188_k127_1228004_3	1379698.RBG1_1C00001G0815	6.468e-61	215.0	COG2316@1|root,COG2316@2|Bacteria,2NP8E@2323|unclassified Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
SRR25158188_k127_1228004_5	469383.Cwoe_1584	2.166e-58	218.0	COG0520@1|root,COG0520@2|Bacteria,2HP42@201174|Actinobacteria,4CQF7@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158188_k127_1228004_6	469383.Cwoe_0777	4.2e-12	79.0	COG3021@1|root,COG3021@2|Bacteria,2HQIN@201174|Actinobacteria,4CS44@84995|Rubrobacteria	84995|Rubrobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158188_k127_1228004_4	469383.Cwoe_0095	1.069e-60	231.0	COG0438@1|root,COG0438@2|Bacteria,2GNPG@201174|Actinobacteria,4CRMS@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRR25158188_k127_1228004_0	1370121.AUWS01000013_gene1114	9.43e-239	758.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,233ZU@1762|Mycobacteriaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158188_k127_1228004_2	223184.AS25_01770	1.67e-75	262.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,1WB3E@1268|Micrococcaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 15	wcoR	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158188_k127_1232619_0	42256.RradSPS_1883	1.698e-78	274.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CSXQ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158188_k127_1232619_3	1122611.KB903974_gene3005	6.8e-30	134.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4EI2N@85012|Streptosporangiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
SRR25158188_k127_1232619_1	1255043.TVNIR_3515	1.629e-42	163.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,1SEMI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158188_k127_1232619_2	1122939.ATUD01000002_gene1419	1.204e-37	146.0	COG3832@1|root,COG3832@2|Bacteria,2ISCU@201174|Actinobacteria,4CQ8K@84995|Rubrobacteria	84995|Rubrobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158188_k127_1232619_4	1380390.JIAT01000013_gene312	3.248e-28	117.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria,4CTKJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158188_k127_1233069_1	290400.Jann_3724	1.086e-44	172.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_11,Methyltransf_25
SRR25158188_k127_1233069_0	469383.Cwoe_1693	5.987e-81	275.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_1238860_4	1380390.JIAT01000011_gene2578	6.428e-75	256.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158188_k127_1238860_0	1304275.C41B8_09941	3.938e-148	487.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,1RQPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine putrescine ABC transporter substrate-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRR25158188_k127_1238860_1	1304275.C41B8_09936	7.421e-103	342.0	COG1176@1|root,COG1176@2|Bacteria,1NU6V@1224|Proteobacteria,1RZ7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter (Permease	ydcU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iEcSMS35_1347.EcSMS35_1732	BPD_transp_1
SRR25158188_k127_1238860_3	1417296.U879_02010	2.032e-93	330.0	COG1177@1|root,COG1177@2|Bacteria,1N3TB@1224|Proteobacteria,2U23R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type spermidine putrescine transport system, permease component II	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158188_k127_1238860_2	675635.Psed_6322	3.628e-95	312.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4E27Q@85010|Pseudonocardiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158188_k127_1258970_4	1380390.JIAT01000014_gene6082	1.32e-51	194.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158188_k127_1258970_6	471855.Shel_26690	1.718e-21	101.0	COG0736@1|root,COG0736@2|Bacteria,2HT7V@201174|Actinobacteria,4CVSA@84998|Coriobacteriia	84998|Coriobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158188_k127_1258970_3	1206101.AZXC01000010_gene211	5.666e-56	210.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158188_k127_1258970_5	1380390.JIAT01000009_gene510	2.194e-30	130.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4CQHQ@84995|Rubrobacteria	84995|Rubrobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158188_k127_1258970_0	196162.Noca_4966	2.726e-189	614.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158188_k127_1258970_1	498848.TaqDRAFT_3947	2.949e-179	581.0	COG0449@1|root,COG0449@2|Bacteria,1WIM6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158188_k127_1258970_2	471852.Tcur_4282	3.203e-89	305.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4EGXD@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158188_k127_1312370_1	526227.Mesil_1867	6.044e-117	383.0	COG0624@1|root,COG0624@2|Bacteria,1WKXT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
SRR25158188_k127_1312370_3	1380390.JIAT01000009_gene1171	9.152e-33	138.0	COG2315@1|root,COG2315@2|Bacteria,2IHRR@201174|Actinobacteria,4CT3I@84995|Rubrobacteria	84995|Rubrobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158188_k127_1312370_2	485913.Krac_11396	9.757e-108	360.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158188_k127_1312370_0	1048339.KB913029_gene1933	3.018e-161	527.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4ES1Y@85013|Frankiales	201174|Actinobacteria	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
SRR25158188_k127_1312370_4	1206726.BAFV01000069_gene4708	1.819e-24	106.0	COG0599@1|root,COG0599@2|Bacteria,2IPIY@201174|Actinobacteria,4G4UW@85025|Nocardiaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158188_k127_1317693_7	1463901.JOIY01000013_gene6029	2.178e-06	49.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158188_k127_1317693_4	1463901.JOIY01000013_gene6028	6.063e-16	81.0	2BDB4@1|root,326ZS@2|Bacteria,2HCK5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1317693_5	195522.BD01_0185	1.364e-12	78.0	COG0526@1|root,arCOG01218@2157|Archaea,2XY63@28890|Euryarchaeota,242P2@183968|Thermococci	183968|Thermococci	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_3
SRR25158188_k127_1317693_6	521045.Kole_0307	1.555e-11	66.0	COG3634@1|root,COG3634@2|Bacteria,2GCUK@200918|Thermotogae	200918|Thermotogae	O	Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SRR25158188_k127_1317693_2	1123073.KB899241_gene2109	9.305e-44	173.0	COG1879@1|root,COG2374@1|root,COG1879@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
SRR25158188_k127_1317693_1	469383.Cwoe_2930	2.244e-57	218.0	COG2159@1|root,COG2159@2|Bacteria,2HJ7X@201174|Actinobacteria,4CPK2@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158188_k127_1317693_3	1382306.JNIM01000001_gene1022	3.655e-38	161.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158188_k127_1317693_0	867903.ThesuDRAFT_01467	7.702e-139	467.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158188_k127_1345847_4	644283.Micau_5703	4.15e-11	64.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4DDT0@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158188_k127_1345847_1	1501230.ET33_10945	4.887e-101	336.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,26R8M@186822|Paenibacillaceae	91061|Bacilli	I	Dehydrogenase	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158188_k127_1345847_0	1283299.AUKG01000002_gene3840	4.469e-134	451.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPUT@84995|Rubrobacteria	84995|Rubrobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_1345847_3	1907.SGLAU_08990	4.971e-35	138.0	COG0454@1|root,COG0456@2|Bacteria,2IHUH@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,CM_2
SRR25158188_k127_1345847_2	1472418.BBJC01000004_gene2063	3.933e-46	181.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158188_k127_1352359_9	1448860.BBJO01000025_gene2971	5.22e-21	99.0	arCOG02998@1|root,arCOG02998@2157|Archaea,2XX29@28890|Euryarchaeota,23VR4@183963|Halobacteria	183963|Halobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_1352359_11	298654.FraEuI1c_5231	1.992e-08	66.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_1352359_4	55952.BU52_06340	5.473e-49	196.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR25158188_k127_1352359_3	469383.Cwoe_3908	2.352e-84	291.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4CSF8@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_1352359_2	1996.JOFO01000014_gene6705	6.849e-86	287.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria	201174|Actinobacteria	S	NAD(P)H-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
SRR25158188_k127_1352359_6	710111.FraQA3DRAFT_0125	1.834e-42	163.0	COG0586@1|root,COG0586@2|Bacteria,2HKKQ@201174|Actinobacteria,4EWF2@85013|Frankiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158188_k127_1352359_8	997346.HMPREF9374_3435	2.77e-26	115.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,27C7P@186824|Thermoactinomycetaceae	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158188_k127_1352359_7	1380390.JIAT01000009_gene1332	3.172e-36	149.0	COG1651@1|root,COG1651@2|Bacteria,2HP5M@201174|Actinobacteria,4CQHM@84995|Rubrobacteria	84995|Rubrobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158188_k127_1352359_0	247490.KSU1_C0355	5.808e-124	409.0	COG1322@1|root,COG1322@2|Bacteria,2J2TY@203682|Planctomycetes	203682|Planctomycetes	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158188_k127_1352359_5	1283299.AUKG01000002_gene3917	3.883e-47	184.0	COG1503@1|root,COG1503@2|Bacteria,2I8DT@201174|Actinobacteria,4CSF4@84995|Rubrobacteria	84995|Rubrobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1352359_1	525904.Tter_1226	8.012e-119	390.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158188_k127_1352359_10	1380390.JIAT01000010_gene4891	3.315e-13	72.0	COG3829@1|root,COG3829@2|Bacteria,2HQG0@201174|Actinobacteria,4CS14@84995|Rubrobacteria	84995|Rubrobacteria	KT	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1353832_5	1449346.JQMO01000003_gene2278	3.106e-42	170.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,2M0PV@2063|Kitasatospora	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158188_k127_1353832_2	390989.JOEG01000003_gene4602	7.739e-116	380.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DADZ@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158188_k127_1353832_0	2002.JOEQ01000031_gene1617	1.77e-237	742.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EH5D@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158188_k127_1353832_8	33876.JNXY01000023_gene5235	6.881e-10	72.0	2E08S@1|root,32VWE@2|Bacteria,2GSZQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1353832_3	219305.MCAG_03593	3.855e-89	320.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4DAUS@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158188_k127_1353832_7	469383.Cwoe_2856	9.716e-13	76.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CPUD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpC family	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158188_k127_1353832_4	227882.SAV_748	3.204e-68	252.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158188_k127_1353832_6	1120949.KB903294_gene4679	1.946e-17	94.0	COG2197@1|root,COG2197@2|Bacteria,2IKTN@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158188_k127_1353832_1	1122182.KB903833_gene5397	5.412e-124	415.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DA29@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158188_k127_1355505_0	1329516.JPST01000036_gene2998	8.699e-198	625.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,27B33@186824|Thermoactinomycetaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158188_k127_1355505_3	443255.SCLAV_3780	3.766e-13	71.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158188_k127_1355505_1	1089544.KB912942_gene1931	1.457e-63	230.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRR25158188_k127_1355505_2	1380390.JIAT01000010_gene4022	2.072e-39	150.0	COG0662@1|root,COG0662@2|Bacteria,2HRBD@201174|Actinobacteria,4CT8K@84995|Rubrobacteria	84995|Rubrobacteria	G	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1355505_4	479434.Sthe_3150	0.0001025	49.0	2ASQB@1|root,31I58@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384,HTH_17
SRR25158188_k127_1355505_5	644966.Tmar_0637	0.0005777	48.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,3WDTF@538999|Clostridiales incertae sedis	186801|Clostridia	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_1358728_2	1449044.JMLE01000028_gene264	6.266e-42	156.0	2DWY1@1|root,342G1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1358728_3	644283.Micau_6186	1.907e-40	164.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158188_k127_1358728_1	469383.Cwoe_2872	2.912e-172	567.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158188_k127_1358728_5	469383.Cwoe_2873	3.318e-31	130.0	COG0237@1|root,COG0237@2|Bacteria,2HG2S@201174|Actinobacteria,4CQK0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158188_k127_1358728_4	1380390.JIAT01000016_gene5587	1.914e-34	144.0	COG0741@1|root,COG0741@2|Bacteria,2GWDB@201174|Actinobacteria,4CQ5G@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158188_k127_1358728_7	40571.JOEA01000025_gene6083	4.768e-17	95.0	2AW22@1|root,31MWT@2|Bacteria,2IKWE@201174|Actinobacteria,4E4ND@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
SRR25158188_k127_1358728_0	469383.Cwoe_3280	4.407e-184	602.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158188_k127_1358728_6	1298863.AUEP01000015_gene1825	9.528e-31	124.0	COG0491@1|root,COG0491@2|Bacteria,2IA0M@201174|Actinobacteria,4DUQH@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_1363221_0	43354.JOIJ01000014_gene854	2.397e-19	97.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4DXYX@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158188_k127_1363221_2	266117.Rxyl_2561	3.552e-07	63.0	COG3119@1|root,COG3119@2|Bacteria,2HRVJ@201174|Actinobacteria,4CTZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1363221_1	266117.Rxyl_1094	3.028e-15	81.0	COG2331@1|root,COG2331@2|Bacteria,2HGE7@201174|Actinobacteria,4CQV7@84995|Rubrobacteria	84995|Rubrobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158188_k127_1363714_2	1162668.LFE_1689	3.85e-62	225.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K05568,ko:K12139	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158188_k127_1363714_1	178901.AmDm5_2242	2.66e-95	331.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2JPNK@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158188_k127_1363714_0	1283299.AUKG01000003_gene292	2.702e-97	336.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158188_k127_1363714_3	861208.AGROH133_06194	2.452e-10	69.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347
SRR25158188_k127_1370044_4	1246995.AFR_23180	1.188e-18	88.0	COG1396@1|root,COG1396@2|Bacteria,2GK0Q@201174|Actinobacteria,4D9RC@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158188_k127_1370044_2	1283299.AUKG01000002_gene5052	5.247e-49	180.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CRPE@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_1370044_3	1283283.ATXA01000003_gene1645	8.432e-37	150.0	2DW3A@1|root,33YCP@2|Bacteria,2GZ8M@201174|Actinobacteria,4EVKN@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158188_k127_1370044_0	1298867.AUES01000040_gene951	1.398e-114	397.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JTJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
SRR25158188_k127_1370044_1	215803.DB30_0399	3.748e-66	246.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158188_k127_1395246_0	1123322.KB904713_gene5176	0.0	1137.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158188_k127_1395246_4	1499968.TCA2_2476	5.225e-31	131.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,26T6D@186822|Paenibacillaceae	91061|Bacilli	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158188_k127_1395246_1	1380394.JADL01000009_gene3405	4.857e-71	252.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria	1224|Proteobacteria	L	5'-3' exonuclease	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158188_k127_1395246_2	479434.Sthe_0918	2.295e-64	241.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,27XTE@189775|Thermomicrobia	189775|Thermomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158188_k127_1395246_3	525904.Tter_1109	1.195e-39	156.0	COG2197@1|root,COG2197@2|Bacteria,2NR2Y@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,HATPase_c,HisKA_3,Response_reg
SRR25158188_k127_1395246_5	479434.Sthe_0156	4.341e-22	112.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158188_k127_1398591_1	469383.Cwoe_3622	4.432e-62	221.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CQ6T@84995|Rubrobacteria	84995|Rubrobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158188_k127_1398591_0	926561.KB900620_gene2875	6.003e-167	539.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WB4K@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158188_k127_140422_0	1123508.JH636444_gene5358	1.406e-187	597.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158188_k127_140422_1	1123320.KB889719_gene7303	6.513e-171	552.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_140422_3	1894.JOER01000047_gene1565	3.041e-75	264.0	2DBTH@1|root,2ZAYC@2|Bacteria,2I31W@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
SRR25158188_k127_140422_2	485913.Krac_5808	8.675e-103	345.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,LTD,PKD,Pro-kuma_activ,fn3
SRR25158188_k127_140422_5	1227457.C451_15403	7.118e-07	61.0	COG0208@1|root,arCOG03658@2157|Archaea,2XTN3@28890|Euryarchaeota,23U06@183963|Halobacteria	183963|Halobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRR25158188_k127_140422_4	266117.Rxyl_2620	8.503e-64	237.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CPA3@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,LPG_synthase_TM
SRR25158188_k127_140422_6	28258.KP05_04415	2.081e-05	56.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XHJ1@135619|Oceanospirillales	135619|Oceanospirillales	P	antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158188_k127_141324_1	926566.Terro_0151	3.145e-59	211.0	COG0508@1|root,COG0508@2|Bacteria,3Y6ID@57723|Acidobacteria,2JM10@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158188_k127_141324_5	926564.KI911760_gene4939	6.644e-28	118.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_141324_0	471852.Tcur_2624	8.254e-62	226.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4EFVN@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158188_k127_141324_3	1121946.AUAX01000002_gene104	6.799e-35	145.0	COG3593@1|root,COG3593@2|Bacteria,2GMN5@201174|Actinobacteria,4DEFR@85008|Micromonosporales	201174|Actinobacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_141324_2	324602.Caur_2835	1.576e-48	182.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158188_k127_141324_4	1380390.JIAT01000013_gene34	5.073e-28	124.0	2ASH4@1|root,31HXG@2|Bacteria,2HMFJ@201174|Actinobacteria,4CQBD@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_141324_6	749927.AMED_1086	1.105e-20	96.0	COG1309@1|root,COG1309@2|Bacteria,2GM0B@201174|Actinobacteria,4E5A8@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	bm3R1_3	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158188_k127_1417742_0	469383.Cwoe_5241	1.66e-251	789.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158188_k127_1426769_2	469383.Cwoe_1389	4.914e-10	62.0	2AXD0@1|root,31PCB@2|Bacteria,2HRSN@201174|Actinobacteria,4CTVR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1426769_1	1121423.JONT01000004_gene1585	1.14e-64	231.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,249R4@186801|Clostridia,260NY@186807|Peptococcaceae	186801|Clostridia	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158188_k127_1426769_0	1122611.KB904003_gene8071	2.437e-82	288.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4EH3S@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme	fadD2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158188_k127_1432250_6	1123023.JIAI01000006_gene93	4.635e-40	156.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4E1WD@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158188_k127_1432250_1	469383.Cwoe_5838	2.171e-151	507.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158188_k127_1432250_2	290397.Adeh_2624	2.958e-80	298.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158188_k127_1432250_8	1007103.AFHW01000082_gene1531	2.192e-21	106.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,26YJD@186822|Paenibacillaceae	91061|Bacilli	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158188_k127_1432250_5	1410634.JHVD01000001_gene1581	1.039e-42	171.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DNV9@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158188_k127_1432250_3	1128421.JAGA01000002_gene1503	1.867e-79	276.0	COG2145@1|root,COG2145@2|Bacteria,2NQTU@2323|unclassified Bacteria	2|Bacteria	H	Hydroxyethylthiazole kinase family	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
SRR25158188_k127_1432250_4	765177.Desmu_0544	1.008e-57	213.0	COG0351@1|root,arCOG00020@2157|Archaea,2XPQB@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM Phosphomethylpyrimidine kinase	thiDN	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K21219,ko:K21220	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
SRR25158188_k127_1432250_10	1206730.BAGA01000079_gene1270	7.919e-13	71.0	2E63U@1|root,31WKG@2|Bacteria,2HY3J@201174|Actinobacteria,4G428@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1432250_7	526227.Mesil_0060	6.704e-40	151.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158188_k127_1432250_0	469383.Cwoe_5571	9.668e-252	807.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4CPIU@84995|Rubrobacteria	84995|Rubrobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158188_k127_1432250_9	1192034.CAP_0198	9.382e-21	94.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158188_k127_143608_6	1033802.SSPSH_003704	0.00073	52.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
SRR25158188_k127_143608_5	1304275.C41B8_06532	0.0005058	53.0	COG2072@1|root,COG2072@2|Bacteria,1N6M9@1224|Proteobacteria,1SRAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRR25158188_k127_143608_3	1380390.JIAT01000009_gene1535	2.407e-116	390.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CRU9@84995|Rubrobacteria	84995|Rubrobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158188_k127_143608_0	1380390.JIAT01000009_gene1536	9.464e-168	543.0	COG1175@1|root,COG1175@2|Bacteria,2GKYS@201174|Actinobacteria,4CRVK@84995|Rubrobacteria	84995|Rubrobacteria	G	SdrD B-like domain	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1,SdrD_B
SRR25158188_k127_143608_2	1380390.JIAT01000009_gene1537	5.991e-140	458.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria,4CS8Q@84995|Rubrobacteria	84995|Rubrobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158188_k127_143608_1	1380390.JIAT01000009_gene1538	1.483e-163	525.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158188_k127_143608_4	1240349.ANGC01000024_gene3585	9.521e-12	66.0	2E5JX@1|root,330B5@2|Bacteria,2GRDA@201174|Actinobacteria,4G48J@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
SRR25158188_k127_1439940_11	1370125.AUWT01000023_gene5769	4.367e-18	87.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,23B9T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158188_k127_1439940_1	1380390.JIAT01000009_gene611	3.476e-66	232.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4CSI7@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158188_k127_1439940_7	1396418.BATQ01000141_gene3341	2.473e-24	108.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	yrkN	-	2.3.1.82	ko:K03826,ko:K03827,ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158188_k127_1439940_6	331869.BAL199_02244	5.001e-28	129.0	COG0454@1|root,COG0456@2|Bacteria,1RIBM@1224|Proteobacteria,2UBNA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158188_k127_1439940_3	2074.JNYD01000029_gene7166	2.084e-43	161.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158188_k127_1439940_8	1298863.AUEP01000011_gene610	4.162e-24	111.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158188_k127_1439940_2	1380346.JNIH01000037_gene3647	4.367e-49	187.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF4111
SRR25158188_k127_1439940_4	439497.RR11_1678	3.237e-42	167.0	COG0346@1|root,COG0346@2|Bacteria,1RIN7@1224|Proteobacteria,2UADI@28211|Alphaproteobacteria,4NCCT@97050|Ruegeria	28211|Alphaproteobacteria	C	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158188_k127_1439940_5	1122129.AUEF01000005_gene2291	6.063e-32	127.0	COG1359@1|root,COG1359@2|Bacteria,1VVKQ@1239|Firmicutes,4HWJS@91061|Bacilli,4H0R9@90964|Staphylococcaceae	91061|Bacilli	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1439940_0	1120950.KB892708_gene4350	2.665e-105	360.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4DRHA@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158188_k127_1439940_10	1202768.JROF01000001_gene1747	4.265e-19	94.0	COG2203@1|root,arCOG03567@1|root,arCOG06712@1|root,arCOG02369@2157|Archaea,arCOG03567@2157|Archaea,arCOG06712@2157|Archaea,2XUM1@28890|Euryarchaeota,23UN4@183963|Halobacteria	183963|Halobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MEDS,PAS_9
SRR25158188_k127_1439940_9	1122609.AUGT01000030_gene2543	8.909e-22	106.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2GM1B@201174|Actinobacteria,4DTFJ@85009|Propionibacteriales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158188_k127_1440244_4	604331.AUHY01000009_gene382	1.12e-19	89.0	COG0624@1|root,COG0624@2|Bacteria,1WKXT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
SRR25158188_k127_1440244_0	1460634.JCM19037_2383	2.288e-170	547.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli	91061|Bacilli	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158188_k127_1440244_3	390989.JOEG01000008_gene1429	9.067e-34	151.0	COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria,4DCUH@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
SRR25158188_k127_1440244_5	1380390.JIAT01000010_gene4366	2.751e-14	87.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,fn3
SRR25158188_k127_1440244_1	266117.Rxyl_2907	3.873e-114	383.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4CRIV@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158188_k127_1440244_2	479435.Kfla_6443	5.061e-53	190.0	COG2128@1|root,COG2128@2|Bacteria,2IG4S@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158188_k127_1448983_1	469383.Cwoe_3774	4.243e-85	302.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158188_k127_1448983_0	469383.Cwoe_3775	1.305e-118	406.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158188_k127_1448983_2	498761.HM1_2051	4.529e-59	208.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158188_k127_1456920_0	469383.Cwoe_5517	2.304e-145	466.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4CPD2@84995|Rubrobacteria	84995|Rubrobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158188_k127_1456920_1	867903.ThesuDRAFT_02195	2.72e-110	379.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes	1239|Firmicutes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158188_k127_1456920_3	1382304.JNIL01000001_gene1030	1.409e-10	74.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158188_k127_1456920_2	243230.DR_1131	2.942e-31	126.0	COG0276@1|root,COG0276@2|Bacteria,1WJEA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158188_k127_1479268_2	1380390.JIAT01000014_gene6067	1.899e-70	257.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CSHZ@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158188_k127_1479268_3	469383.Cwoe_1901	6.673e-53	213.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158188_k127_1479268_0	1380390.JIAT01000014_gene6065	2.868e-280	892.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CS3H@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRR25158188_k127_1479268_1	469383.Cwoe_1903	4.678e-72	257.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria	201174|Actinobacteria	C	I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158188_k127_1481593_4	1463857.JOFZ01000007_gene100	1.436e-05	49.0	COG0477@1|root,COG0477@2|Bacteria,2GJ9D@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_1481593_1	1206741.BAFX01000081_gene6255	6.95e-39	152.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,4FUCJ@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	acnR	GO:0000287,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21962	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158188_k127_1481593_2	1380390.JIAT01000010_gene4201	3.351e-18	92.0	2AUS7@1|root,31KF8@2|Bacteria,2HPA6@201174|Actinobacteria,4CQNH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158188_k127_1481593_3	1500306.JQLA01000014_gene1931	1.987e-17	94.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2TSJV@28211|Alphaproteobacteria,4B9X3@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Belongs to the RuBisCO large chain family	rbcL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
SRR25158188_k127_1481593_0	469383.Cwoe_1011	6.938e-88	295.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CPHV@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease NucS	-	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158188_k127_1481593_5	446470.Snas_4688	0.0002934	48.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_1509484_1	203119.Cthe_1079	5.725e-92	319.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,3WGIE@541000|Ruminococcaceae	186801|Clostridia	GJM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
SRR25158188_k127_1509484_3	1321775.HMPREF1980_00754	1.003e-22	113.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4D4I7@85005|Actinomycetales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158188_k127_1509484_0	266117.Rxyl_0584	3.09e-97	329.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4CPN7@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158188_k127_1509484_2	1380390.JIAT01000009_gene1043	6.416e-62	231.0	COG0662@1|root,COG0662@2|Bacteria,2GZ5U@201174|Actinobacteria,4CSXN@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_1514216_0	439235.Dalk_1526	4.234e-86	315.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158188_k127_1514216_1	1321782.HMPREF1986_01834	4.286e-11	63.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,2PRQZ@265975|Oribacterium	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158188_k127_1518739_0	1385519.N801_08280	8.056e-158	512.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FGIN@85021|Intrasporangiaceae	201174|Actinobacteria	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_1518739_2	1385519.N801_08285	5.251e-53	193.0	COG1309@1|root,COG1309@2|Bacteria,2IM68@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158188_k127_1518739_1	219305.MCAG_04009	2.373e-107	360.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria,4D9GQ@85008|Micromonosporales	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158188_k127_1518739_3	1394178.AWOO02000089_gene1096	1.866e-37	151.0	COG0596@1|root,COG0596@2|Bacteria,2I8EU@201174|Actinobacteria,4EQPH@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	lipV	GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575	-	ko:K19311	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158188_k127_1518739_4	1449346.JQMO01000003_gene3019	9.229e-11	64.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,2M0KK@2063|Kitasatospora	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158188_k127_1520670_2	269800.Tfu_0910	1.198e-127	420.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4EI1N@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_1520670_1	66869.JNXG01000019_gene1461	6.195e-143	461.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,41CFR@629295|Streptomyces griseus group	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_1520670_3	1122962.AULH01000001_gene1437	8.008e-113	380.0	COG1173@1|root,COG1173@2|Bacteria,1R4JX@1224|Proteobacteria,2U2MZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158188_k127_1520670_0	269800.Tfu_0913	1.147e-143	462.0	COG0444@1|root,COG0444@2|Bacteria,2IAWG@201174|Actinobacteria,4EIAY@85012|Streptosporangiales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_1520670_4	446468.Ndas_3653	2.331e-107	370.0	COG4608@1|root,COG4608@2|Bacteria,2IBD7@201174|Actinobacteria,4EH91@85012|Streptosporangiales	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_1530932_0	1283299.AUKG01000001_gene1343	1.912e-131	444.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4CR4Q@84995|Rubrobacteria	84995|Rubrobacteria	G	glycoside hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158188_k127_1530932_1	1120936.KB907211_gene293	9.478e-93	321.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4EGAT@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
SRR25158188_k127_1530932_2	452652.KSE_02340	6.256e-61	214.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
SRR25158188_k127_153552_8	525909.Afer_1707	2.135e-42	162.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CNMG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRR25158188_k127_153552_3	1121877.JQKF01000024_gene2409	2.887e-72	258.0	COG1622@1|root,COG1622@2|Bacteria,2HGN7@201174|Actinobacteria,4CNP4@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRR25158188_k127_153552_7	525909.Afer_1709	9.126e-43	165.0	arCOG07408@1|root,2ZWPP@2|Bacteria,2HGM2@201174|Actinobacteria,4CNJ3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_153552_4	66874.JOFS01000012_gene4867	1.26e-62	224.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_153552_6	1348663.KCH_12280	5.366e-55	208.0	COG0642@1|root,COG2205@2|Bacteria,2II4F@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158188_k127_153552_9	1382356.JQMP01000004_gene436	3.483e-42	177.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,27XSP@189775|Thermomicrobia	189775|Thermomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158188_k127_153552_0	469383.Cwoe_2859	4.634e-149	488.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CP72@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158188_k127_153552_10	1122609.AUGT01000012_gene4354	5.976e-37	160.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158188_k127_153552_1	644966.Tmar_1454	1.747e-101	342.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3WCZN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158188_k127_153552_5	913325.N799_06730	4.358e-59	222.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1X41Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158188_k127_153552_2	192875.XP_004363753.1	2.604e-91	316.0	COG0147@1|root,KOG1223@2759|Eukaryota,38FJ5@33154|Opisthokonta	33154|Opisthokonta	E	anthranilate synthase activity	TRP2	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158188_k127_153552_11	1109445.AGSX01000125_gene2471	9.202e-05	45.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,1S72Y@1236|Gammaproteobacteria,1Z47T@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
SRR25158188_k127_1538509_2	1079986.JH164842_gene5970	2.067e-61	235.0	COG2113@1|root,COG2113@2|Bacteria,2GP39@201174|Actinobacteria	201174|Actinobacteria	E	glycine betaine transport	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158188_k127_1538509_1	570268.ANBB01000055_gene4885	5.999e-130	440.0	COG4176@1|root,COG4176@2|Bacteria,2GKRF@201174|Actinobacteria,4EFZH@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	proW	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158188_k127_1538509_0	479432.Sros_1796	2.272e-135	439.0	COG4175@1|root,COG4175@2|Bacteria,2GJC0@201174|Actinobacteria,4EGWC@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158188_k127_1538509_3	467661.RKLH11_2198	4.395e-19	86.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	alh	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158188_k127_1543557_2	469383.Cwoe_3327	6.11e-40	170.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Laminin_G_3
SRR25158188_k127_1543557_3	467200.ACFA01000529_gene4292	3.626e-25	123.0	COG3391@1|root,COG3391@2|Bacteria,2GNC3@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1543557_0	2002.JOEQ01000001_gene4644	6.155e-71	256.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4EJ0G@85012|Streptosporangiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_1543557_1	469383.Cwoe_5241	2.161e-66	246.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158188_k127_1552551_2	1232410.KI421415_gene2955	9.813e-88	297.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,43RZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	elongation factor Tu domain 2 protein	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158188_k127_1552551_0	1307761.L21SP2_0748	4.692e-147	482.0	COG2939@1|root,COG2939@2|Bacteria	2|Bacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRR25158188_k127_1552551_3	429009.Adeg_1121	6.561e-28	117.0	COG1695@1|root,COG1695@2|Bacteria,1V7D3@1239|Firmicutes,24ME9@186801|Clostridia,42HAY@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158188_k127_1552551_4	1380390.JIAT01000010_gene4284	1.602e-16	88.0	2AT5U@1|root,31IN3@2|Bacteria,2HN2Z@201174|Actinobacteria,4CQH5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1552551_1	749927.AMED_5332	9.552e-98	330.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria,4E2YQ@85010|Pseudonocardiales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158188_k127_155804_4	1380390.JIAT01000009_gene1894	2.99e-47	180.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4CPIG@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158188_k127_155804_5	1169161.KB897721_gene4208	5.764e-38	156.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria	201174|Actinobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158188_k127_155804_2	471852.Tcur_4459	3.903e-82	281.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4EHTN@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158188_k127_155804_9	1089549.AZUQ01000001_gene2083	4.544e-10	72.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4EYA6@85014|Glycomycetales	201174|Actinobacteria	FL	AlkA N-terminal domain	alkA	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158188_k127_155804_7	1463887.KL589973_gene1371	2.098e-33	141.0	2CMWR@1|root,32SFR@2|Bacteria,2IHG8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_155804_3	479434.Sthe_2979	2.072e-70	247.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi,27YFG@189775|Thermomicrobia	189775|Thermomicrobia	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158188_k127_155804_1	235985.BBPN01000001_gene1080	8.767e-84	287.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NJ3P@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_155804_0	981369.JQMJ01000004_gene5277	1.787e-121	396.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NFPR@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158188_k127_155804_6	1123319.AUBE01000006_gene3333	2.677e-37	147.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158188_k127_1569756_1	1298863.AUEP01000004_gene2240	8.8e-101	336.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4DU8X@85009|Propionibacteriales	201174|Actinobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
SRR25158188_k127_1569756_0	1449976.KALB_2196	3.753e-136	444.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158188_k127_157020_0	266117.Rxyl_2016	0.0	1026.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158188_k127_157020_1	1452536.JARE01000048_gene918	4.514e-89	310.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4FM52@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158188_k127_157020_2	479434.Sthe_0699	7.403e-68	252.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158188_k127_157020_3	446471.Xcel_1643	4.478e-45	178.0	COG5495@1|root,COG5495@2|Bacteria,2IK43@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520
SRR25158188_k127_157020_4	1122138.AQUZ01000085_gene8800	2.045e-34	141.0	COG3629@1|root,COG3629@2|Bacteria,2GM4U@201174|Actinobacteria,4DUTC@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158188_k127_1586420_2	552811.Dehly_0600	2.149e-19	98.0	COG1295@1|root,COG1295@2|Bacteria,2G7DE@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158188_k127_1586420_0	1313304.CALK_0256	1.942e-35	144.0	COG0127@1|root,COG0127@2|Bacteria	2|Bacteria	F	nucleoside triphosphate catabolic process	rdgB	-	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Ham1p_like
SRR25158188_k127_1586420_1	266117.Rxyl_2934	2.066e-33	135.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158188_k127_1596852_2	1449355.JQNR01000003_gene936	3.675e-17	85.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria	201174|Actinobacteria	S	Metal-dependent hydrolases of the beta-lactamase superfamily III	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158188_k127_1596852_3	1121912.AUHD01000011_gene685	8.123e-05	52.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1HYXD@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRR25158188_k127_1596852_1	408672.NBCG_02651	1.48e-19	91.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158188_k127_1596852_0	1380356.JNIK01000015_gene2305	2.203e-34	138.0	COG3217@1|root,COG3217@2|Bacteria,2HU2E@201174|Actinobacteria,4EWKT@85013|Frankiales	201174|Actinobacteria	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158188_k127_159776_0	266117.Rxyl_1205	0.0	1442.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4CRPX@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SRR25158188_k127_159776_1	42256.RradSPS_0572	3.793e-80	276.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4CQM5@84995|Rubrobacteria	84995|Rubrobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRR25158188_k127_1597844_0	1283299.AUKG01000003_gene544	1.176e-288	904.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPC3@84995|Rubrobacteria	84995|Rubrobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158188_k127_1597844_2	469383.Cwoe_5832	7.981e-38	156.0	COG1877@1|root,COG1877@2|Bacteria,2HP2R@201174|Actinobacteria,4CQDQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158188_k127_1597844_1	1283299.AUKG01000002_gene5287	2.986e-43	162.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4CTA5@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158188_k127_1597844_3	555088.DealDRAFT_2852	4.499e-24	104.0	COG0076@1|root,COG0076@2|Bacteria,1TSK0@1239|Firmicutes,24A90@186801|Clostridia	186801|Clostridia	E	pyridoxal-dependent decarboxylase	ddc	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158188_k127_1618155_2	469383.Cwoe_3228	1.912e-34	136.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158188_k127_1618155_0	1120949.KB903328_gene8876	1.678e-89	317.0	COG0747@1|root,COG3391@1|root,COG3629@1|root,COG0747@2|Bacteria,COG3391@2|Bacteria,COG3629@2|Bacteria,2GJXH@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_1618155_3	1296990.H845_163	1.169e-30	140.0	COG0747@1|root,COG0747@2|Bacteria,1R6Z4@1224|Proteobacteria,2TUSS@28211|Alphaproteobacteria,2JPAA@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_1618155_1	502025.Hoch_2300	1.271e-75	262.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_1618228_2	469383.Cwoe_4586	5.634e-46	181.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CPSH@84995|Rubrobacteria	84995|Rubrobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158188_k127_1618228_1	42256.RradSPS_1558	6.992e-81	293.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CPHA@84995|Rubrobacteria	84995|Rubrobacteria	D	ATPases associated with a variety of cellular activities	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158188_k127_1618228_0	1380390.JIAT01000001_gene5131	4.213e-107	351.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158188_k127_1627481_2	469383.Cwoe_2142	4.065e-116	385.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4CSVS@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158188_k127_1627481_6	469383.Cwoe_4191	1.074e-28	119.0	COG2127@1|root,COG2127@2|Bacteria,2HPG0@201174|Actinobacteria,4CQUJ@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158188_k127_1627481_5	379066.GAU_3910	7.085e-31	137.0	COG3663@1|root,COG3663@2|Bacteria,1ZTNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158188_k127_1627481_0	469383.Cwoe_3480	3.836e-177	569.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158188_k127_1627481_1	469383.Cwoe_4177	6.077e-131	433.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_1627481_9	644966.Tmar_1853	3.825e-14	86.0	COG1309@1|root,COG1309@2|Bacteria,1V4AJ@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	betI1	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158188_k127_1627481_8	1298880.AUEV01000002_gene1752	2.754e-20	104.0	COG1396@1|root,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8
SRR25158188_k127_1627481_3	1051632.TPY_1209	3.329e-75	273.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia	186801|Clostridia	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH,Pkinase
SRR25158188_k127_1627481_4	1122939.ATUD01000005_gene2678	2.304e-51	191.0	COG4221@1|root,COG4221@2|Bacteria,2I5BD@201174|Actinobacteria,4CPN3@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158188_k127_1627481_7	1128421.JAGA01000002_gene1133	2.607e-26	109.0	COG0709@1|root,COG0709@2|Bacteria,2NNUD@2323|unclassified Bacteria	2|Bacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
SRR25158188_k127_1627621_2	1380390.JIAT01000010_gene4142	3.296e-61	222.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CPND@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158188_k127_1627621_1	1380390.JIAT01000010_gene4143	7.252e-88	303.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CPF5@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158188_k127_1627621_0	469383.Cwoe_3772	1.27e-89	310.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158188_k127_1627621_3	1283299.AUKG01000002_gene4620	1.486e-59	225.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CPQK@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158188_k127_1630379_3	1380390.JIAT01000010_gene4177	6.433e-19	93.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158188_k127_1630379_0	1068978.AMETH_3272	7.665e-39	148.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria,4EB5A@85010|Pseudonocardiales	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158188_k127_1630379_1	471852.Tcur_2353	2.824e-30	123.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_1630379_2	269799.Gmet_1295	1.378e-25	109.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,43S56@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158188_k127_1636598_1	1449126.JQKL01000017_gene2766	3.459e-82	282.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,267PJ@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_1636598_4	351160.RCIX1436	1.578e-05	56.0	COG0449@1|root,arCOG00057@2157|Archaea,2XTC0@28890|Euryarchaeota,2N92X@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158188_k127_1636598_3	416348.Hlac_2975	1.126e-10	72.0	arCOG08099@1|root,arCOG08099@2157|Archaea,2Y8AQ@28890|Euryarchaeota,2417K@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1636598_0	469383.Cwoe_3270	5.183e-135	444.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158188_k127_1636598_2	264732.Moth_0995	1.401e-14	76.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,42FTD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM CobB CobQ domain protein glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158188_k127_1649339_8	1122132.AQYH01000007_gene2078	4.421e-50	185.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158188_k127_1649339_5	367299.JOEE01000007_gene189	8.287e-65	232.0	COG0457@1|root,COG0457@2|Bacteria,2H5WR@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158188_k127_1649339_3	367299.JOEE01000003_gene2716	3.402e-111	383.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4FG8B@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158188_k127_1649339_9	365528.KB891274_gene2692	7.191e-50	198.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_1649339_2	926550.CLDAP_06280	2.887e-116	396.0	COG2141@1|root,COG3255@1|root,COG2141@2|Bacteria,COG3255@2|Bacteria,2G878@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158188_k127_1649339_10	1307759.JOMJ01000004_gene2508	2.357e-39	158.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,42XKF@68525|delta/epsilon subdivisions,2WT6J@28221|Deltaproteobacteria,2M8UX@213115|Desulfovibrionales	28221|Deltaproteobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158188_k127_1649339_13	298655.KI912266_gene990	0.0005626	51.0	2B9SB@1|root,32350@2|Bacteria,2H7QG@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158188_k127_1649339_4	469383.Cwoe_3717	6.412e-86	295.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_1649339_11	1283299.AUKG01000002_gene4673	4.993e-29	122.0	COG2197@1|root,COG2197@2|Bacteria,2I5RT@201174|Actinobacteria,4CST9@84995|Rubrobacteria	84995|Rubrobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158188_k127_1649339_0	1380390.JIAT01000009_gene460	1.39e-230	739.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CSH3@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158188_k127_1649339_1	1380390.JIAT01000010_gene3904	5.042e-217	696.0	COG2203@1|root,COG3447@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3447@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF4118,GAF,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158188_k127_1649339_6	755732.Fluta_2190	3.935e-61	217.0	COG2120@1|root,COG2120@2|Bacteria,4NN16@976|Bacteroidetes	976|Bacteroidetes	S	PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158188_k127_1649339_7	1380390.JIAT01000009_gene1700	1.796e-59	226.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158188_k127_1665956_1	1122604.JONR01000040_gene4069	3.69e-67	237.0	COG1502@1|root,COG1502@2|Bacteria,1R9CI@1224|Proteobacteria,1SJMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158188_k127_1665956_0	1120960.ATXG01000011_gene3561	6.301e-81	289.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria,4FQMK@85023|Microbacteriaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158188_k127_1665956_2	1380390.JIAT01000015_gene5734	3.357e-10	66.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Laminin_G_3,Phosphoesterase
SRR25158188_k127_1666839_10	1283299.AUKG01000004_gene1095	1.543e-06	59.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158188_k127_1666839_5	469383.Cwoe_2898	2.077e-28	125.0	COG1214@1|root,COG1214@2|Bacteria,2HP59@201174|Actinobacteria,4CQH7@84995|Rubrobacteria	84995|Rubrobacteria	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158188_k127_1666839_4	1122939.ATUD01000004_gene3702	8.507e-30	124.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158188_k127_1666839_7	1123504.JQKD01000020_gene5624	1.302e-20	102.0	COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,2VU5B@28216|Betaproteobacteria,4AEZ1@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158188_k127_1666839_2	1120950.KB892771_gene1312	3.613e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria,4DRJF@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_1666839_8	656024.FsymDg_0487	5.009e-10	69.0	2BH5R@1|root,32B6W@2|Bacteria,2GYG1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1666839_1	469383.Cwoe_2893	3.872e-64	233.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158188_k127_1666839_6	323261.Noc_2571	1.713e-23	108.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales	135613|Chromatiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158188_k127_1666839_9	330214.NIDE1855	1.351e-09	61.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158188_k127_1666839_3	1214242.B446_34775	2.751e-48	182.0	COG4291@1|root,COG4291@2|Bacteria,2GIW8@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRR25158188_k127_1666839_0	882083.SacmaDRAFT_2977	5.476e-96	326.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria,4E17H@85010|Pseudonocardiales	201174|Actinobacteria	V	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_1668613_1	765420.OSCT_2203	1.733e-40	164.0	COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158188_k127_1668613_0	1298863.AUEP01000001_gene949	8.535e-50	195.0	COG2385@1|root,COG2385@2|Bacteria,2I2J0@201174|Actinobacteria,4DQBJ@85009|Propionibacteriales	201174|Actinobacteria	D	PFAM Stage II sporulation D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SpoIID,VCBS
SRR25158188_k127_1668613_2	266117.Rxyl_1125	5.086e-18	87.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158188_k127_1707591_5	1283299.AUKG01000001_gene1901	5.14e-13	78.0	COG3307@1|root,COG3307@2|Bacteria,2HQNN@201174|Actinobacteria,4CS9D@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158188_k127_1707591_3	1382356.JQMP01000001_gene1020	1.356e-61	231.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158188_k127_1707591_0	1380390.JIAT01000014_gene6174	1.953e-106	360.0	COG0673@1|root,COG0673@2|Bacteria,2HPZE@201174|Actinobacteria,4CREW@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158188_k127_1707591_4	945713.IALB_2449	2.157e-55	198.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
SRR25158188_k127_1707591_1	404380.Gbem_1067	2.598e-94	323.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158188_k127_1707591_6	1179773.BN6_40940	1.492e-11	77.0	28J8U@1|root,33EE0@2|Bacteria,2GTXS@201174|Actinobacteria,4E270@85010|Pseudonocardiales	201174|Actinobacteria	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
SRR25158188_k127_1707591_2	861299.J421_3503	7.144e-71	252.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158188_k127_1707591_7	1211815.CBYP010000034_gene2129	2.568e-05	49.0	COG0438@1|root,COG0438@2|Bacteria,2GSQI@201174|Actinobacteria,4ES49@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_1715583_2	1399115.U719_05060	2.735e-54	200.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1U7NI@1239|Firmicutes,4HA3E@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_7,Response_reg
SRR25158188_k127_1715583_3	1156844.KB891799_gene1276	6.465e-05	48.0	28R4V@1|root,2ZDJ5@2|Bacteria,2IQ7D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1715583_1	469383.Cwoe_1903	1.93e-62	228.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria	201174|Actinobacteria	C	I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158188_k127_1715583_0	469383.Cwoe_1902	2.994e-84	286.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158188_k127_171813_1	1394178.AWOO02000026_gene5112	6.332e-68	239.0	COG0555@1|root,COG0555@2|Bacteria,2I4C5@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02018,ko:K15496	ko02010,map02010	M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
SRR25158188_k127_171813_0	525904.Tter_2326	1.175e-74	263.0	COG1613@1|root,COG1613@2|Bacteria,2NQGY@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	subI	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN678.sbpA	SBP_bac_11
SRR25158188_k127_171813_3	1278078.G419_02540	1.587e-42	159.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4G18A@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158188_k127_171813_2	1380390.JIAT01000010_gene4280	9.158e-57	209.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CSHN@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158188_k127_171813_4	518766.Rmar_0210	4.986e-40	153.0	COG1053@1|root,COG1053@2|Bacteria,4NHXK@976|Bacteroidetes,1FJ4E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158188_k127_1724228_0	1123388.AQWU01000073_gene1162	7.44e-136	448.0	COG0160@1|root,COG0160@2|Bacteria,1WIP2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158188_k127_1724228_2	446471.Xcel_3189	2.362e-81	275.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4F3FX@85017|Promicromonosporaceae	201174|Actinobacteria	F	2'-deoxycytidine 5'-triphosphate deaminase (DCD)	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158188_k127_1724228_3	1183438.GKIL_1022	1.136e-49	195.0	COG0702@1|root,COG0702@2|Bacteria,1GHPI@1117|Cyanobacteria	1117|Cyanobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRR25158188_k127_1724228_1	1303518.CCALI_00698	3.183e-84	289.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	adhC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158188_k127_1727469_2	1120950.KB892796_gene2257	5.175e-48	173.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4DSFS@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR25158188_k127_1727469_4	536019.Mesop_1308	1.852e-19	99.0	2EK0M@1|root,33DR5@2|Bacteria,1NKNS@1224|Proteobacteria,2UNJZ@28211|Alphaproteobacteria,43P8N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRR25158188_k127_1727469_5	926560.KE387023_gene2853	2.444e-15	79.0	COG1225@1|root,COG1225@2|Bacteria,1WKA8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158188_k127_1727469_0	1283299.AUKG01000003_gene594	1.042e-102	364.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4CPB8@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158188_k127_1727469_8	62928.azo0107	2.083e-09	68.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2VH6D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158188_k127_1727469_3	1198114.AciX9_2257	9.155e-34	142.0	COG0251@1|root,COG0251@2|Bacteria,3Y540@57723|Acidobacteria,2JJVI@204432|Acidobacteriia	204432|Acidobacteriia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158188_k127_1727469_1	1223523.H340_17126	1.538e-93	321.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_1727469_7	1385521.N803_02155	1.041e-11	72.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158188_k127_1727469_6	1120983.KB894574_gene1087	1.956e-14	74.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,1JP8P@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158188_k127_1740105_2	446470.Snas_3745	6.487e-40	156.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4EZP1@85014|Glycomycetales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_1740105_3	1146883.BLASA_0946	1.969e-34	140.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EVFA@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158188_k127_1740105_1	68219.JNXI01000002_gene4185	3.525e-53	202.0	COG5002@1|root,COG5002@2|Bacteria,2GP6S@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158188_k127_1740105_0	1463858.JOHR01000001_gene6561	7.472e-75	259.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_1740105_4	929712.KI912613_gene2019	1.914e-21	96.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	fdnI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158188_k127_1756384_5	1173028.ANKO01000112_gene4868	1.422e-29	123.0	2E7MG@1|root,3323C@2|Bacteria,1GCRI@1117|Cyanobacteria,1HFKH@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158188_k127_1756384_2	1173028.ANKO01000112_gene4869	7.952e-59	220.0	COG1493@1|root,COG1493@2|Bacteria,1GD1X@1117|Cyanobacteria,1HE2B@1150|Oscillatoriales	1117|Cyanobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1756384_4	395961.Cyan7425_3355	3.507e-34	147.0	COG1216@1|root,COG1216@2|Bacteria,1G2A7@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158188_k127_1756384_1	643473.KB235930_gene3900	5.92e-64	229.0	COG1216@1|root,COG1216@2|Bacteria,1G2VA@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2
SRR25158188_k127_1756384_3	696747.NIES39_D07050	1.277e-45	179.0	COG0451@1|root,COG0451@2|Bacteria,1G3P6@1117|Cyanobacteria,1HAGS@1150|Oscillatoriales	1117|Cyanobacteria	GM	Male sterility protein	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158188_k127_1756384_0	1380390.JIAT01000014_gene6297	1.178e-83	310.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4CSZF@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
SRR25158188_k127_1756384_6	643473.KB235930_gene3907	1.493e-19	105.0	2DECI@1|root,32U34@2|Bacteria	2|Bacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158188_k127_1756384_7	706439.HMPREF9057_00574	2.888e-08	68.0	28J8U@1|root,2Z93Z@2|Bacteria,2IDZ4@201174|Actinobacteria,4D3QP@85005|Actinomycetales	201174|Actinobacteria	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
SRR25158188_k127_1793696_2	1043493.BBLU01000010_gene212	2.635e-18	89.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158188_k127_1793696_1	562970.Btus_0101	2.066e-76	264.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,27805@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158188_k127_1793696_0	388051.AUFE01000036_gene4053	6.701e-77	276.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,2VJCW@28216|Betaproteobacteria,1K4DW@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158188_k127_1808120_0	351607.Acel_0552	8.184e-95	326.0	COG1653@1|root,COG1653@2|Bacteria,2GN08@201174|Actinobacteria,4ETH8@85013|Frankiales	201174|Actinobacteria	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
SRR25158188_k127_1808120_1	351607.Acel_0553	3.022e-82	285.0	COG1175@1|root,COG1175@2|Bacteria,2GX5P@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17330	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR25158188_k127_1808120_2	68570.DC74_7771	1.049e-78	286.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	dasC	-	-	ko:K17331	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
SRR25158188_k127_1808120_3	67315.JOBD01000012_gene455	5.856e-61	217.0	COG3525@1|root,COG3525@2|Bacteria,2H28J@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
SRR25158188_k127_1810514_3	469383.Cwoe_1919	7.843e-26	114.0	COG1765@1|root,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria,4CQ86@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158188_k127_1810514_1	1353537.TP2_04470	1.373e-32	130.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2XMWG@285107|Thioclava	28211|Alphaproteobacteria	O	Tetratricopeptide repeat	trxA2	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158188_k127_1810514_2	1048339.KB913029_gene2505	4.341e-32	137.0	COG0640@1|root,COG0640@2|Bacteria,2IRF0@201174|Actinobacteria,4EWG5@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158188_k127_1810514_0	1380390.JIAT01000009_gene649	6.708e-47	174.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158188_k127_181195_1	479434.Sthe_0838	2.237e-69	243.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158188_k127_181195_2	675635.Psed_3403	5.722e-30	137.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4DYYZ@85010|Pseudonocardiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158188_k127_181195_0	469383.Cwoe_5826	8.708e-80	275.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158188_k127_1820452_3	1283283.ATXA01000003_gene1367	4.63e-06	57.0	COG0392@1|root,COG0392@2|Bacteria,2HU1H@201174|Actinobacteria,4EWCT@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158188_k127_1820452_0	290397.Adeh_1060	3.813e-123	408.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,42R49@68525|delta/epsilon subdivisions,2WNEZ@28221|Deltaproteobacteria,2YU32@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158188_k127_1820452_1	1283299.AUKG01000001_gene1664	3.305e-56	220.0	COG1216@1|root,COG1216@2|Bacteria,2HU9H@201174|Actinobacteria,4CPRC@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158188_k127_1820452_2	1148.1652968	1.473e-26	124.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1H6W3@1142|Synechocystis	1117|Cyanobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg
SRR25158188_k127_182320_10	1120705.FG95_03684	2.355e-09	63.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2TSWT@28211|Alphaproteobacteria,2K2C6@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_182320_3	1232410.KI421424_gene1592	2.597e-68	249.0	COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158188_k127_182320_1	1380390.JIAT01000015_gene5807	3.582e-144	465.0	COG3185@1|root,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria	201174|Actinobacteria	E	4-hydroxyphenylpyruvate dioxygenase	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
SRR25158188_k127_182320_6	1007103.AFHW01000025_gene338	2.698e-41	173.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158188_k127_182320_2	1380390.JIAT01000014_gene6100	1.332e-118	396.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CPB0@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158188_k127_182320_9	1283299.AUKG01000002_gene4217	1.426e-20	98.0	COG0179@1|root,COG0179@2|Bacteria,2GMSJ@201174|Actinobacteria,4CRK3@84995|Rubrobacteria	84995|Rubrobacteria	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158188_k127_182320_5	285535.JOEY01000008_gene8736	1.414e-55	210.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158188_k127_182320_0	1380390.JIAT01000015_gene5806	7.78e-147	481.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria	201174|Actinobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158188_k127_182320_4	1380390.JIAT01000010_gene3874	1.27e-63	226.0	COG3832@1|root,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158188_k127_182320_7	997346.HMPREF9374_2024	8.947e-34	140.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,27BP3@186824|Thermoactinomycetaceae	91061|Bacilli	L	endonuclease III	yfjP	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158188_k127_182320_11	797209.ZOD2009_04437	2.765e-05	55.0	COG0454@1|root,arCOG00826@2157|Archaea,2XY8J@28890|Euryarchaeota,23W5E@183963|Halobacteria	183963|Halobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	pai1	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158188_k127_182320_8	765910.MARPU_01480	5.061e-27	123.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1WWWN@135613|Chromatiales	135613|Chromatiales	O	PFAM Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N_3
SRR25158188_k127_182320_12	1033806.HTIA_2527	0.0004641	51.0	COG2897@1|root,arCOG02019@2157|Archaea	2157|Archaea	P	COG2897 Rhodanese-related sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158188_k127_182365_0	469383.Cwoe_0843	1.194e-238	750.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158188_k127_182365_3	1183438.GKIL_2106	6.104e-43	171.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SRR25158188_k127_182365_2	1380390.JIAT01000009_gene377	1.81e-62	216.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4CQ6D@84995|Rubrobacteria	84995|Rubrobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158188_k127_182365_1	273068.TTE0544	3.59e-69	248.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158188_k127_182365_4	469383.Cwoe_0896	2.285e-21	110.0	COG0739@1|root,COG3409@1|root,COG0739@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,PG_binding_1,Peptidase_M23
SRR25158188_k127_182365_5	929712.KI912613_gene4307	1.972e-19	104.0	COG0741@1|root,COG0741@2|Bacteria,2IBV1@201174|Actinobacteria,4CR3Y@84995|Rubrobacteria	84995|Rubrobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR25158188_k127_1846547_1	1380390.JIAT01000009_gene1788	1.509e-271	858.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158188_k127_1846547_0	1380390.JIAT01000009_gene1787	2.595e-274	859.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CP85@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158188_k127_1872096_5	1227457.C451_18783	1.053e-41	158.0	COG4948@1|root,arCOG01168@2157|Archaea,2XUAK@28890|Euryarchaeota,23S9R@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158188_k127_1872096_1	1379270.AUXF01000004_gene3060	1.019e-88	306.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
SRR25158188_k127_1872096_6	469383.Cwoe_3196	5.797e-40	161.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4CQCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158188_k127_1872096_7	266117.Rxyl_0857	3.189e-08	58.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158188_k127_1872096_3	1128421.JAGA01000002_gene1198	1.597e-46	171.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K15945	ko01057,ko01130,map01057,map01130	-	R09330	RC00046	ko00000,ko00001	-	-	-	SnoaL,SnoaL_2
SRR25158188_k127_1872096_0	469383.Cwoe_3197	1.203e-104	349.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,4CRBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158188_k127_1872096_4	1123023.JIAI01000003_gene2728	3.524e-44	171.0	COG0030@1|root,COG0030@2|Bacteria,2H1TK@201174|Actinobacteria,4DXHF@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermE	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
SRR25158188_k127_1872096_2	469383.Cwoe_5326	1.54e-62	220.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria,4CPBH@84995|Rubrobacteria	84995|Rubrobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158188_k127_1889631_0	1179773.BN6_08500	2.684e-133	438.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_1889631_1	285535.JOEY01000060_gene9003	2.109e-69	239.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_1897138_1	101510.RHA1_ro05586	1.175e-42	162.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FZ9I@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
SRR25158188_k127_1897138_0	1298863.AUEP01000004_gene1990	3.172e-194	627.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4DPS5@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_1899580_5	1160721.RBI_I00187	1.208e-20	93.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3WGHS@541000|Ruminococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158188_k127_1899580_6	469383.Cwoe_5929	1.088e-19	98.0	2AWJ7@1|root,31NFU@2|Bacteria,2HR1C@201174|Actinobacteria,4CSVI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1899580_1	439235.Dalk_1526	7.014e-99	363.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158188_k127_1899580_3	1209989.TepiRe1_0041	6.61e-44	186.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,42FZA@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158188_k127_1899580_0	596152.DesU5LDRAFT_1994	8.214e-172	552.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2M9H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Carboxylyase-related protein	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158188_k127_1899580_4	1122939.ATUD01000013_gene913	6.582e-23	110.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria,4CQW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158188_k127_1899580_2	469383.Cwoe_5927	4.62e-81	279.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158188_k127_1899580_7	469383.Cwoe_5926	5.187e-16	82.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
SRR25158188_k127_1903859_7	686340.Metal_2474	5.15e-07	61.0	COG1721@1|root,COG1721@2|Bacteria,1R69F@1224|Proteobacteria,1S8QT@1236|Gammaproteobacteria,1XEZS@135618|Methylococcales	135618|Methylococcales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1903859_2	326427.Cagg_1592	8.465e-102	342.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158188_k127_1903859_6	1123258.AQXZ01000015_gene4527	1.339e-46	171.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_1903859_5	1417296.U879_02010	8.18e-84	295.0	COG1177@1|root,COG1177@2|Bacteria,1N3TB@1224|Proteobacteria,2U23R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type spermidine putrescine transport system, permease component II	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158188_k127_1903859_3	1304275.C41B8_09936	7.947e-101	336.0	COG1176@1|root,COG1176@2|Bacteria,1NU6V@1224|Proteobacteria,1RZ7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter (Permease	ydcU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iEcSMS35_1347.EcSMS35_1732	BPD_transp_1
SRR25158188_k127_1903859_0	1304275.C41B8_09941	6.361e-142	467.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,1RQPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine putrescine ABC transporter substrate-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRR25158188_k127_1903859_1	1380390.JIAT01000011_gene2578	9.486e-135	438.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158188_k127_1903859_4	1211115.ALIQ01000189_gene811	4.769e-86	292.0	COG0160@1|root,COG0160@2|Bacteria,1QY1E@1224|Proteobacteria,2TYR4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158188_k127_191191_1	981369.JQMJ01000004_gene4964	1.411e-65	226.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,2NKD9@228398|Streptacidiphilus	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158188_k127_191191_7	290397.Adeh_3812	1.343e-27	119.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,43AM1@68525|delta/epsilon subdivisions,2X616@28221|Deltaproteobacteria,2Z388@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158188_k127_191191_4	1123073.KB899242_gene1305	1.548e-43	170.0	COG5646@1|root,COG5646@2|Bacteria,1QB2A@1224|Proteobacteria,1T6JI@1236|Gammaproteobacteria,1X7N4@135614|Xanthomonadales	135614|Xanthomonadales	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158188_k127_191191_6	378806.STAUR_7457	1.87e-30	130.0	COG3832@1|root,COG3832@2|Bacteria,1MZXG@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158188_k127_191191_5	1121926.AXWO01000020_gene2035	5.313e-32	143.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4EYET@85014|Glycomycetales	201174|Actinobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158188_k127_191191_2	208444.JNYY01000022_gene3124	1.199e-57	213.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria,4E1ES@85010|Pseudonocardiales	201174|Actinobacteria	EH	aminodeoxychorismate synthase	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Chorismate_bind
SRR25158188_k127_191191_0	1289387.AUKW01000002_gene360	9.309e-121	400.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
SRR25158188_k127_191191_3	675635.Psed_3297	2.293e-45	167.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158188_k127_1916072_8	349163.Acry_1074	4.629e-12	68.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	cysP	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306,ko:K16331	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.4	-	-	PHO4
SRR25158188_k127_1916072_7	573061.Clocel_0311	3.83e-14	80.0	COG3409@1|root,COG3409@2|Bacteria,1UUY0@1239|Firmicutes,24C6K@186801|Clostridia,36FQZ@31979|Clostridiaceae	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,SH3_3
SRR25158188_k127_1916072_1	1173022.Cri9333_1867	5.362e-62	234.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HF9F@1150|Oscillatoriales	1117|Cyanobacteria	T	Domain of unknown function (DUF4118)	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,DUF4118,GAF_2,HATPase_c,HisKA,PAS_10,PAS_3,PAS_9,Response_reg
SRR25158188_k127_1916072_4	675635.Psed_2381	2.085e-42	175.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
SRR25158188_k127_1916072_2	631454.N177_0027	2.219e-55	201.0	COG3791@1|root,COG3791@2|Bacteria,1PSHU@1224|Proteobacteria,2VANI@28211|Alphaproteobacteria,1JQJ6@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158188_k127_1916072_5	1122939.ATUD01000001_gene148	5.561e-36	140.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158188_k127_1916072_6	285535.JOEY01000012_gene5633	1.341e-15	83.0	COG1670@1|root,COG1670@2|Bacteria,2IKXU@201174|Actinobacteria	201174|Actinobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_1916072_3	595537.Varpa_4304	4.066e-43	169.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,4A9YD@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_1916072_0	469383.Cwoe_0822	1.077e-154	501.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158188_k127_1937864_1	419610.Mext_1733	3.543e-58	222.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,1JRKB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM ABC transporter	tauB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158188_k127_1937864_2	1463855.JOHV01000020_gene3024	2.578e-55	204.0	COG0600@1|root,COG0600@2|Bacteria,2HDX7@201174|Actinobacteria	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158188_k127_1937864_0	926554.KI912637_gene3217	5.036e-65	225.0	COG0624@1|root,COG0624@2|Bacteria,1WKXT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
SRR25158188_k127_194028_4	1416759.AYMR01000003_gene3373	3.047e-38	147.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4FR84@85023|Microbacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_194028_1	330084.JNYZ01000005_gene928	4.643e-117	385.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,4DZ95@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_194028_3	1320556.AVBP01000030_gene140	2.257e-104	360.0	COG1173@1|root,COG1173@2|Bacteria,1NRWG@1224|Proteobacteria,2UPAF@28211|Alphaproteobacteria,43PKS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_194028_2	330084.JNYZ01000005_gene930	6.036e-112	385.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_194028_0	1123023.JIAI01000004_gene7859	1.685e-129	430.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4E9Z4@85010|Pseudonocardiales	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_194028_6	1463845.JOIG01000004_gene4321	3.666e-05	47.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria	201174|Actinobacteria	E	(mono)amine oxidase	aofH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158188_k127_194028_5	1045009.AFXQ01000007_gene2940	2.426e-23	109.0	COG1231@1|root,COG1231@2|Bacteria,2HTKA@201174|Actinobacteria,1WBN9@1268|Micrococcaceae	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158188_k127_1941608_6	1121346.KB899824_gene3017	1.597e-22	105.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,26USM@186822|Paenibacillaceae	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158188_k127_1941608_7	1122132.AQYH01000018_gene1111	4.721e-08	65.0	COG1539@1|root,COG1539@2|Bacteria,1RHII@1224|Proteobacteria,2U66Y@28211|Alphaproteobacteria,4BE81@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158188_k127_1941608_1	469383.Cwoe_1674	6.123e-86	295.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CPWZ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158188_k127_1941608_2	251221.35211202	3.609e-84	303.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
SRR25158188_k127_1941608_4	1122138.AQUZ01000047_gene100	3.206e-54	195.0	COG5485@1|root,COG5485@2|Bacteria,2HPCH@201174|Actinobacteria,4DSK3@85009|Propionibacteriales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158188_k127_1941608_5	1169152.AXVD01000010_gene4449	2.785e-40	156.0	COG3153@1|root,COG3153@2|Bacteria,2IKX0@201174|Actinobacteria,4G0F1@85025|Nocardiaceae	201174|Actinobacteria	Q	Acetyltransferase (GNAT) family	-	-	-	ko:K03824,ko:K09964	-	-	-	-	ko00000,ko01000	-	-	-	ACT_3,ACT_7,Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
SRR25158188_k127_1941608_0	1306406.ASHX01000001_gene882	2.192e-163	522.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158188_k127_1968896_5	1283299.AUKG01000002_gene5236	9.041e-33	131.0	COG3829@1|root,COG3829@2|Bacteria,2HQG0@201174|Actinobacteria,4CS14@84995|Rubrobacteria	84995|Rubrobacteria	KT	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_1968896_6	316067.Geob_1946	1.081e-24	108.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,43V55@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158188_k127_1968896_4	1122221.JHVI01000013_gene2767	9.081e-40	152.0	COG1993@1|root,COG1993@2|Bacteria,1WKB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SRR25158188_k127_1968896_2	1380390.JIAT01000013_gene64	2.668e-56	208.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158188_k127_1968896_3	525368.HMPREF0591_3953	1.481e-44	171.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,232JV@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_1968896_1	1195236.CTER_0531	1.882e-57	209.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158188_k127_1968896_0	1380390.JIAT01000014_gene6206	3.39e-169	571.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CPD7@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158188_k127_1970732_9	665956.HMPREF1032_02061	6.663e-95	319.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158188_k127_1970732_0	469383.Cwoe_3616	3.517e-172	578.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CP7V@84995|Rubrobacteria	84995|Rubrobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158188_k127_1970732_19	862751.SACTE_5223	9.018e-12	71.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158188_k127_1970732_22	479434.Sthe_0746	4.451e-05	51.0	COG0517@1|root,COG0517@2|Bacteria,2GBF7@200795|Chloroflexi,27ZA2@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized protein conserved in bacteria (DUF2171)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF2171
SRR25158188_k127_1970732_12	1240349.ANGC01000066_gene90	1.46e-78	274.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4FUP9@85025|Nocardiaceae	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158188_k127_1970732_3	1120971.AUCA01000034_gene3111	5.446e-119	390.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,2788A@186823|Alicyclobacillaceae	91061|Bacilli	C	Transketolase, pyrimidine binding domain	acoB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158188_k127_1970732_11	1237500.ANBA01000012_gene5151	1.182e-80	289.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4EN87@85012|Streptosporangiales	201174|Actinobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158188_k127_1970732_21	446469.Sked_16350	3.15e-05	50.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_1970732_16	42256.RradSPS_2294	2.71e-27	117.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158188_k127_1970732_8	935836.JAEL01000139_gene652	1.966e-101	346.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZCM1@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	acoL	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158188_k127_1970732_10	555088.DealDRAFT_0299	5.339e-94	321.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,42JMR@68298|Syntrophomonadaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158188_k127_1970732_18	479434.Sthe_0161	1.892e-23	114.0	COG2211@1|root,COG2211@2|Bacteria,2G6UD@200795|Chloroflexi,27XXJ@189775|Thermomicrobia	189775|Thermomicrobia	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158188_k127_1970732_5	1283299.AUKG01000002_gene3829	1.142e-105	353.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CQB3@84995|Rubrobacteria	84995|Rubrobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158188_k127_1970732_7	1121946.AUAX01000003_gene1395	8.334e-103	351.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DB0R@85008|Micromonosporales	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158188_k127_1970732_13	1128421.JAGA01000001_gene2030	2.674e-69	255.0	COG1524@1|root,COG1524@2|Bacteria,2NQ0M@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158188_k127_1970732_2	1150864.MILUP08_45186	1.274e-142	494.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158188_k127_1970732_14	1122609.AUGT01000021_gene1160	1.771e-54	198.0	COG1296@1|root,COG1296@2|Bacteria,2IJ35@201174|Actinobacteria,4DRRJ@85009|Propionibacteriales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158188_k127_1970732_20	1380390.JIAT01000010_gene4605	6.154e-11	73.0	2DT93@1|root,33J8Y@2|Bacteria,2HRXC@201174|Actinobacteria,4CU0G@84995|Rubrobacteria	84995|Rubrobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158188_k127_1970732_6	479434.Sthe_2134	2.295e-105	357.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158188_k127_1970732_15	1380390.JIAT01000001_gene5135	5.939e-29	132.0	COG3336@1|root,COG3336@2|Bacteria,2GSID@201174|Actinobacteria,4CRYT@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158188_k127_1970732_17	1283299.AUKG01000003_gene235	5.084e-25	117.0	COG3336@1|root,COG3336@2|Bacteria,2HPY7@201174|Actinobacteria,4CRDE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158188_k127_1970732_1	469383.Cwoe_0232	2.243e-151	492.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4CPRK@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_1970732_4	1380390.JIAT01000010_gene4343	3.515e-106	364.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158188_k127_1977449_3	1449976.KALB_2916	4.328e-48	195.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158188_k127_1977449_2	469383.Cwoe_5036	1.213e-75	257.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158188_k127_1977449_1	263358.VAB18032_27071	1.329e-145	515.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158188_k127_1977449_0	469383.Cwoe_5792	0.0	1027.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4CPU9@84995|Rubrobacteria	84995|Rubrobacteria	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158188_k127_1990667_3	682795.AciX8_2177	4.52e-43	167.0	COG0596@1|root,COG0596@2|Bacteria,3Y5W5@57723|Acidobacteria,2JKEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158188_k127_1990667_4	1463936.JOJI01000024_gene1240	5.134e-41	160.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158188_k127_1990667_0	926569.ANT_28320	0.0	1330.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158188_k127_1990667_1	1386089.N865_16800	1.627e-159	516.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRR25158188_k127_1990667_2	1122221.JHVI01000018_gene1488	1.151e-156	506.0	COG2723@1|root,COG2723@2|Bacteria,1WIBW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glycosyl hydrolase family 1	-	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
SRR25158188_k127_2018270_2	469383.Cwoe_3233	3.667e-40	161.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158188_k127_2018270_1	1380390.JIAT01000010_gene3592	4.152e-109	374.0	COG2199@1|root,COG3706@2|Bacteria,2I3N8@201174|Actinobacteria	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158188_k127_2018270_0	929712.KI912613_gene3571	3.09e-112	370.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CPRU@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158188_k127_2020818_7	2074.JNYD01000033_gene6367	4.778e-10	65.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2020818_1	1068978.AMETH_4230	8.063e-76	266.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4E882@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158188_k127_2020818_4	469383.Cwoe_5722	4.646e-33	133.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4CSVU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2020818_2	469383.Cwoe_1100	1.195e-67	232.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CQGA@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158188_k127_2020818_8	1125863.JAFN01000001_gene659	1.591e-09	68.0	COG2340@1|root,COG2730@1|root,COG2931@1|root,COG2340@2|Bacteria,COG2730@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	CAP,Calx-beta,Cellulase,Glyco_hydro_115,Glyco_hydro_67N
SRR25158188_k127_2020818_9	1449069.JMLO01000004_gene3716	7.562e-07	61.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4FVX4@85025|Nocardiaceae	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158188_k127_2020818_0	469383.Cwoe_5282	2.367e-162	525.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158188_k127_2020818_10	748247.AZKH_0707	0.0005209	50.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KUD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
SRR25158188_k127_2020818_3	1157708.KB907464_gene366	4.722e-64	225.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2VRIW@28216|Betaproteobacteria,4AECX@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158188_k127_2020818_5	479431.Namu_5022	4.247e-32	134.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4ET19@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158188_k127_2020818_6	1123023.JIAI01000002_gene5834	1.044e-27	113.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DZV3@85010|Pseudonocardiales	201174|Actinobacteria	EU	Dipeptidyl aminopeptidase acylaminoacyl peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158188_k127_2020928_0	326427.Cagg_3091	1.029e-98	333.0	COG0145@1|root,COG0145@2|Bacteria,2GAHE@200795|Chloroflexi,37658@32061|Chloroflexia	32061|Chloroflexia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158188_k127_2020928_1	1429046.RR21198_0138	2.536e-89	306.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4G8ME@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158188_k127_2020928_2	1394178.AWOO02000006_gene3436	1.158e-58	217.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158188_k127_2020928_3	1231391.AMZF01000092_gene35	2.278e-31	127.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VHRA@28216|Betaproteobacteria,3T37Q@506|Alcaligenaceae	28216|Betaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441,ko:K10562	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	ABC_tran
SRR25158188_k127_2022270_1	1283299.AUKG01000001_gene3505	1.248e-214	674.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4CQ88@84995|Rubrobacteria	84995|Rubrobacteria	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158188_k127_2022270_0	1283299.AUKG01000001_gene3504	4.734e-229	724.0	COG1288@1|root,COG1288@2|Bacteria,2HK5U@201174|Actinobacteria,4CRGE@84995|Rubrobacteria	84995|Rubrobacteria	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
SRR25158188_k127_2022270_2	1245471.PCA10_30630	9.735e-157	506.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158188_k127_2024693_7	1122939.ATUD01000007_gene2102	1.728e-43	165.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4CRWR@84995|Rubrobacteria	84995|Rubrobacteria	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158188_k127_2024693_4	1169152.AXVD01000003_gene4660	1.558e-66	243.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FUQS@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2024693_2	1003195.SCAT_4645	4.859e-138	466.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158188_k127_2024693_9	552811.Dehly_1509	1.137e-07	66.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi,34DAT@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158188_k127_2024693_1	469383.Cwoe_2908	3.966e-164	537.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2GJ75@201174|Actinobacteria,4CPFI@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
SRR25158188_k127_2024693_3	469383.Cwoe_2910	1.33e-97	342.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2HF4S@201174|Actinobacteria,4CPSY@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
SRR25158188_k127_2024693_8	1382356.JQMP01000004_gene330	1.47e-33	134.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,27YE9@189775|Thermomicrobia	189775|Thermomicrobia	C	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158188_k127_2024693_5	1380390.JIAT01000016_gene5498	7.812e-64	238.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CPKV@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158188_k127_2024693_0	1267535.KB906767_gene5499	7.934e-172	563.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,PQQ_2,PQQ_3
SRR25158188_k127_2024693_10	1121926.AXWO01000014_gene1832	0.0005154	49.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4EYWK@85014|Glycomycetales	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	hisE	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158188_k127_2024693_6	1151061.CAJY01000033_gene1912	1.219e-63	233.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158188_k127_2035552_1	1896.JOAU01000001_gene4305	9.48e-121	394.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158188_k127_2035552_2	469378.Ccur_07120	4.215e-32	140.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4CUY0@84998|Coriobacteriia	84998|Coriobacteriia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158188_k127_2035552_3	1287475.HMPREF1650_04880	3.837e-18	95.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,22NSG@1653|Corynebacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158188_k127_2035552_0	518766.Rmar_1231	2.126e-224	714.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1FIW6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
SRR25158188_k127_2035552_4	929712.KI912613_gene3009	2.626e-16	79.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158188_k127_2037122_6	1122939.ATUD01000004_gene3935	1.637e-78	270.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4CPTF@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158188_k127_2037122_0	713586.KB900536_gene50	9.056e-302	948.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158188_k127_2037122_1	1122939.ATUD01000004_gene3937	1.079e-219	703.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4CPMZ@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158188_k127_2037122_9	1304872.JAGC01000003_gene2391	8.754e-13	74.0	COG3613@1|root,COG3613@2|Bacteria,1MZSA@1224|Proteobacteria,42XC4@68525|delta/epsilon subdivisions,2WT4P@28221|Deltaproteobacteria,2MBRI@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
SRR25158188_k127_2037122_8	1463887.KL590036_gene3621	4.111e-42	163.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2037122_2	469383.Cwoe_0293	3.592e-95	321.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CPYK@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2037122_5	469383.Cwoe_0292	1.892e-79	288.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CRHZ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158188_k127_2037122_4	1283299.AUKG01000005_gene146	3.619e-82	296.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4CREI@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158188_k127_2037122_3	110319.CF8_3611	6.181e-91	304.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DP6U@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2037122_7	292459.STH749	3.805e-49	198.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158188_k127_2039511_10	1149133.ppKF707_5389	3.858e-28	119.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1YFHM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Conserved carboxylase domain	oadA	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_5346	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158188_k127_2039511_1	211114.JOEF01000003_gene3183	9.172e-117	386.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4E3AB@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_2039511_5	1329516.JPST01000065_gene1810	5.715e-61	223.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,27ATS@186824|Thermoactinomycetaceae	91061|Bacilli	J	Elongation factor P (EF-P) OB domain	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158188_k127_2039511_4	246194.CHY_1873	4.879e-74	263.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,42F13@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM peptidase M24	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158188_k127_2039511_7	929712.KI912613_gene3456	1.384e-42	160.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158188_k127_2039511_3	1380390.JIAT01000017_gene5275	1.409e-78	282.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158188_k127_2039511_2	1125863.JAFN01000001_gene2282	4.075e-108	361.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
SRR25158188_k127_2039511_9	1121430.JMLG01000021_gene1382	3.668e-30	130.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158188_k127_2039511_8	1380390.JIAT01000017_gene5302	1.396e-41	168.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158188_k127_2039511_11	469383.Cwoe_3035	1.733e-26	117.0	COG0816@1|root,COG0816@2|Bacteria,2HPE8@201174|Actinobacteria,4CQSC@84995|Rubrobacteria	84995|Rubrobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158188_k127_2039511_0	1283299.AUKG01000004_gene971	1.587e-209	695.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158188_k127_2039511_6	340099.Teth39_1138	1.643e-48	186.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,42F4N@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158188_k127_2039827_0	469383.Cwoe_1313	1.083e-234	739.0	COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria,4CR1F@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_2039827_9	929712.KI912613_gene3681	1.109e-12	73.0	COG2149@1|root,COG2149@2|Bacteria,2HTN4@201174|Actinobacteria,4CSZK@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158188_k127_2039827_3	1089552.KI911559_gene975	1.252e-76	263.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
SRR25158188_k127_2039827_4	525909.Afer_0701	9.401e-51	196.0	29BBV@1|root,2ZYA6@2|Bacteria,2ICWN@201174|Actinobacteria,4CNPC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
SRR25158188_k127_2039827_10	1122152.AUEI01000004_gene979	5.698e-10	70.0	COG4990@1|root,COG4990@2|Bacteria,1V7GB@1239|Firmicutes,4I28M@91061|Bacilli,3F5VT@33958|Lactobacillaceae	91061|Bacilli	G	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_C39_2,SH3_8,SLAP
SRR25158188_k127_2039827_5	1121877.JQKF01000013_gene272	1.142e-36	152.0	COG0500@1|root,COG2226@2|Bacteria,2HGMM@201174|Actinobacteria,4CNKY@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_2039827_7	525904.Tter_2127	2.702e-16	88.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158188_k127_2039827_6	357808.RoseRS_0609	1.633e-36	154.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,375JB@32061|Chloroflexia	32061|Chloroflexia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158188_k127_2039827_1	749414.SBI_02531	3.014e-97	344.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158188_k127_2039827_2	1155718.KB891883_gene5944	2.445e-77	266.0	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	tcsR4	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2055109_3	1380390.JIAT01000015_gene5878	1.859e-39	157.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria	201174|Actinobacteria	D	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158188_k127_2055109_2	285535.JOEY01000086_gene7178	6.309e-113	379.0	COG2267@1|root,COG2267@2|Bacteria,2IBIY@201174|Actinobacteria	201174|Actinobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158188_k127_2055109_6	1120953.AUBH01000001_gene585	2.334e-24	116.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158188_k127_2055109_1	1283299.AUKG01000001_gene2400	1.402e-119	414.0	COG4934@1|root,COG4934@2|Bacteria,2GMZ8@201174|Actinobacteria,4CR8X@84995|Rubrobacteria	84995|Rubrobacteria	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
SRR25158188_k127_2055109_4	28444.JODQ01000009_gene3811	2.004e-37	150.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4EFP1@85012|Streptosporangiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158188_k127_2055109_5	671065.MetMK1DRAFT_00029870	2.409e-28	120.0	COG0432@1|root,arCOG04214@2157|Archaea,2XQYP@28889|Crenarchaeota	28889|Crenarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158188_k127_2055109_0	1121272.KB903293_gene7408	2.934e-253	815.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4D9FU@85008|Micromonosporales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
SRR25158188_k127_2055181_5	1283283.ATXA01000014_gene3606	1.602e-05	57.0	2EW6V@1|root,33PJT@2|Bacteria,2H3RP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2055181_3	469383.Cwoe_1795	6.085e-35	143.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	ykuD	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
SRR25158188_k127_2055181_0	1157632.AQWQ01000001_gene6151	3.892e-98	328.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,TIG
SRR25158188_k127_2055181_2	1968.JOEV01000003_gene3206	4.383e-45	175.0	COG2203@1|root,COG2203@2|Bacteria,2I97I@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
SRR25158188_k127_2055181_1	1385519.N801_16125	6.315e-91	319.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158188_k127_2055181_4	390989.JOEG01000012_gene3325	3.283e-09	65.0	COG3404@1|root,COG3404@2|Bacteria,2IIRF@201174|Actinobacteria,4DG1Q@85008|Micromonosporales	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SRR25158188_k127_2086530_6	266117.Rxyl_0510	2.846e-51	183.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158188_k127_2086530_0	68570.DC74_4465	5.776e-150	485.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158188_k127_2086530_3	469383.Cwoe_5289	4.767e-72	256.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158188_k127_2086530_1	429009.Adeg_0882	9.682e-88	316.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,42EN4@68295|Thermoanaerobacterales	186801|Clostridia	E	homoserine dehydrogenase NAD-binding	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158188_k127_2086530_4	1121121.KB894300_gene1677	1.054e-65	249.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,26RAH@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06615,iYO844.BSU32250	PALP
SRR25158188_k127_2086530_7	584708.Apau_1718	3.893e-32	143.0	COG0083@1|root,COG0083@2|Bacteria,3T9RY@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158188_k127_2086530_9	414996.IL38_01730	5.574e-09	67.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158188_k127_2086530_10	575609.HMPREF0629_01387	3.302e-06	53.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,22HY2@1570339|Peptoniphilaceae	186801|Clostridia	S	cog cog1302	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158188_k127_2086530_8	765420.OSCT_0513	5.012e-25	119.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi,375MG@32061|Chloroflexia	32061|Chloroflexia	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158188_k127_2086530_2	436114.SYO3AOP1_0375	4.109e-77	271.0	COG2048@1|root,COG2048@2|Bacteria,2G3SY@200783|Aquificae	200783|Aquificae	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00241,ko:K03389	ko00020,ko00190,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00356,M00357,M00374,M00376,M00563,M00567	R02164,R04540,R11928,R11931,R11943,R11944	RC00011,RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
SRR25158188_k127_2086530_5	1131269.AQVV01000001_gene1358	3.377e-61	226.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158188_k127_2114086_5	1283287.KB822575_gene233	9.544e-16	90.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria,4DWX6@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16
SRR25158188_k127_2114086_3	1380386.JIAW01000011_gene3294	7.527e-35	137.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,23A1C@1762|Mycobacteriaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158188_k127_2114086_0	103733.JNYO01000043_gene5945	2.34e-131	453.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria,4DY9X@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158188_k127_2114086_2	273677.BW34_01169	6.018e-56	205.0	COG1335@1|root,COG1335@2|Bacteria,2I77A@201174|Actinobacteria,4FNC6@85023|Microbacteriaceae	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158188_k127_2114086_4	1392493.JIAB01000001_gene2589	2.098e-26	123.0	COG0584@1|root,COG0584@2|Bacteria,1UR2E@1239|Firmicutes,258VY@186801|Clostridia,27M9Z@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
SRR25158188_k127_2114086_1	28444.JODQ01000013_gene2906	2.778e-64	226.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EHMJ@85012|Streptosporangiales	201174|Actinobacteria	E	TOBE domain	-	-	-	ko:K02052,ko:K11084	ko02010,ko02024,map02010,map02024	M00193,M00302	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.5	-	-	ABC_tran,TOBE_2
SRR25158188_k127_2123273_0	525904.Tter_0881	1.101e-215	677.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158188_k127_2123273_2	981369.JQMJ01000004_gene1238	5.752e-63	226.0	COG0789@1|root,COG0789@2|Bacteria,2IC98@201174|Actinobacteria,2NGH2@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158188_k127_2123273_1	309801.trd_1505	3.823e-98	337.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158188_k127_2123273_4	3075.A0A087SDG8	5.363e-11	74.0	COG0449@1|root,KOG1268@2759|Eukaryota,37JZC@33090|Viridiplantae,34GRX@3041|Chlorophyta	3041|Chlorophyta	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158188_k127_2123273_3	709986.Deima_1485	2.65e-20	93.0	COG0520@1|root,COG0520@2|Bacteria,1WIPV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158188_k127_2141555_1	867903.ThesuDRAFT_01249	3.769e-87	316.0	COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,24AKC@186801|Clostridia	186801|Clostridia	C	Acetamidase formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
SRR25158188_k127_2141555_0	326427.Cagg_1321	1.177e-107	367.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158188_k127_2141555_2	700508.D174_16670	4.714e-69	246.0	COG1177@1|root,COG1177@2|Bacteria,2ISUW@201174|Actinobacteria,23AV2@1762|Mycobacteriaceae	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158188_k127_2141555_3	1268072.PSAB_20205	1.38e-11	67.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,26RH5@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158188_k127_2151247_4	498761.HM1_0315	4.412e-35	138.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158188_k127_2151247_1	292459.STH849	1.05e-66	243.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158188_k127_2151247_5	1397527.Q670_14800	7.743e-21	94.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1XM21@135619|Oceanospirillales	135619|Oceanospirillales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158188_k127_2151247_3	1380390.JIAT01000003_gene5463	7.95e-50	186.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158188_k127_2151247_0	1380390.JIAT01000009_gene767	1.015e-188	601.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CP9U@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158188_k127_2151247_2	446471.Xcel_3205	6.409e-64	228.0	COG1806@1|root,COG1806@2|Bacteria,2IDD1@201174|Actinobacteria,4F5EG@85017|Promicromonosporaceae	201174|Actinobacteria	S	Kinase/pyrophosphorylase	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
SRR25158188_k127_2153566_3	1206101.AZXC01000007_gene2590	5.62e-96	322.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158188_k127_2153566_1	1121861.KB899946_gene3939	2.72e-149	481.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,2JR9U@204441|Rhodospirillales	204441|Rhodospirillales	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158188_k127_2153566_8	77635.BISU_0216	2.266e-14	85.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4D1XS@85004|Bifidobacteriales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158188_k127_2153566_6	156978.CIMIT_09915	3.695e-27	119.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,22NV0@1653|Corynebacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158188_k127_2153566_0	928724.SacglDRAFT_02949	2.848e-272	855.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158188_k127_2153566_7	1121877.JQKF01000029_gene2101	2.692e-15	77.0	COG2608@1|root,COG2608@2|Bacteria,2GXF6@201174|Actinobacteria	201174|Actinobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR25158188_k127_2153566_4	1298863.AUEP01000006_gene3361	9.201e-56	198.0	COG2132@1|root,COG2132@2|Bacteria,2I386@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158188_k127_2153566_2	1380370.JIBA01000015_gene98	5.299e-125	433.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158188_k127_2153566_5	1380390.JIAT01000009_gene1429	8.174e-54	194.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4CRT3@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158188_k127_2154915_2	675635.Psed_1200	5.303e-76	265.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DZV3@85010|Pseudonocardiales	201174|Actinobacteria	EU	Dipeptidyl aminopeptidase acylaminoacyl peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158188_k127_2154915_3	266117.Rxyl_1538	9.382e-69	250.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CPX5@84995|Rubrobacteria	84995|Rubrobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158188_k127_2154915_1	469383.Cwoe_2648	2.214e-90	304.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158188_k127_2154915_0	555079.Toce_1766	1.737e-166	540.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158188_k127_2157053_1	404589.Anae109_2517	9.608e-53	191.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
SRR25158188_k127_2157053_0	1283299.AUKG01000001_gene1945	4.771e-136	463.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4CPQE@84995|Rubrobacteria	84995|Rubrobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158188_k127_2157053_2	909663.KI867150_gene2033	1.352e-09	70.0	COG0392@1|root,COG0392@2|Bacteria,1N7DR@1224|Proteobacteria,42N4R@68525|delta/epsilon subdivisions,2WS5Z@28221|Deltaproteobacteria,2MSHP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158188_k127_2159689_3	405948.SACE_3168	1.316e-47	175.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4E5A2@85010|Pseudonocardiales	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158188_k127_2159689_0	1464048.JNZS01000020_gene2226	1.818e-151	486.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria,4DBMB@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158188_k127_2159689_4	1370121.AUWS01000010_gene5938	6.928e-25	120.0	COG0589@1|root,COG0589@2|Bacteria,2GU2B@201174|Actinobacteria	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158188_k127_2159689_1	591158.SSMG_07476	5.155e-144	474.0	COG0531@1|root,COG0531@2|Bacteria,2GIWQ@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158188_k127_2159689_2	266117.Rxyl_3196	1.278e-115	381.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,4CPBS@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158188_k127_2172825_2	1380390.JIAT01000014_gene6094	2.183e-90	307.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158188_k127_2172825_0	1382356.JQMP01000003_gene1431	3.379e-224	705.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158188_k127_2172825_1	1114959.SZMC14600_18324	2.916e-135	441.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4DXUU@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158188_k127_2174629_13	1283299.AUKG01000001_gene2009	0.0006055	49.0	2BNEF@1|root,32H24@2|Bacteria,2HR3R@201174|Actinobacteria,4CSZ4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2174629_5	1380390.JIAT01000009_gene341	2.578e-73	256.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158188_k127_2174629_0	986075.CathTA2_2809	5.876e-209	660.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158188_k127_2174629_9	929712.KI912613_gene2878	2.781e-21	100.0	COG0712@1|root,COG0712@2|Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRR25158188_k127_2174629_8	469383.Cwoe_4622	1.315e-29	124.0	COG0711@1|root,COG0711@2|Bacteria,2HR5V@201174|Actinobacteria,4CT1D@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158188_k127_2174629_10	929712.KI912613_gene2876	3.178e-20	93.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158188_k127_2174629_7	469383.Cwoe_4624	2.005e-48	186.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CQG3@84995|Rubrobacteria	84995|Rubrobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158188_k127_2174629_6	136273.GY22_04940	5.135e-63	229.0	COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria,1WABF@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158188_k127_2174629_4	1380390.JIAT01000009_gene360	2.615e-84	293.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CQIN@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158188_k127_2174629_3	1381751.JAJB01000001_gene2879	9.47e-96	326.0	COG3214@1|root,COG3214@2|Bacteria,2HPNB@201174|Actinobacteria,4FB40@85019|Brevibacteriaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158188_k127_2174629_12	56110.Oscil6304_4950	1.281e-05	53.0	COG3453@1|root,COG3453@2|Bacteria,1G5H7@1117|Cyanobacteria,1HBVW@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
SRR25158188_k127_2174629_1	105422.BBPM01000097_gene5229	8.845e-163	548.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,2NH21@228398|Streptacidiphilus	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158188_k127_2174629_2	1304865.JAGF01000001_gene234	5.136e-114	377.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria	201174|Actinobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158188_k127_2174629_11	398512.JQKC01000002_gene1990	2.596e-17	81.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3WGYU@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158188_k127_2194076_0	1380390.JIAT01000013_gene145	2.653e-178	597.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158188_k127_2198713_3	1120950.KB892752_gene6157	4.384e-55	201.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DNWF@85009|Propionibacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158188_k127_2198713_5	717606.PaecuDRAFT_1416	1.219e-31	137.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,276F7@186822|Paenibacillaceae	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
SRR25158188_k127_2198713_2	469383.Cwoe_5239	2.945e-78	269.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CQXI@84995|Rubrobacteria	84995|Rubrobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRR25158188_k127_2198713_0	1283299.AUKG01000003_gene585	1.55e-175	570.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CPAA@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158188_k127_2198713_4	446470.Snas_5106	1.231e-34	153.0	COG3173@1|root,COG3173@2|Bacteria,2I4EA@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158188_k127_2198713_1	1121430.JMLG01000005_gene742	1.902e-129	429.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRR25158188_k127_2198713_8	1380390.JIAT01000009_gene717	0.0001969	49.0	COG2919@1|root,COG2919@2|Bacteria,2HRMQ@201174|Actinobacteria,4CTPQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158188_k127_2198713_6	1150864.MILUP08_40985	4.538e-26	119.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4DCTN@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158188_k127_2198713_7	1283299.AUKG01000003_gene587	2.14e-05	53.0	2AUU5@1|root,31KH9@2|Bacteria,2HPC7@201174|Actinobacteria,4CQQB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2201204_0	929712.KI912613_gene3423	4.003e-101	342.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158188_k127_2201204_4	1380390.JIAT01000017_gene5278	2.072e-07	61.0	2AVF2@1|root,31M71@2|Bacteria,2HPWF@201174|Actinobacteria,4CRB2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM
SRR25158188_k127_2201204_3	1380390.JIAT01000017_gene5279	8.777e-09	66.0	COG3166@1|root,COG3166@2|Bacteria,2HPHC@201174|Actinobacteria,4CQVM@84995|Rubrobacteria	84995|Rubrobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2201204_2	446469.Sked_17820	1.283e-27	127.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria	201174|Actinobacteria	NU	pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158188_k127_2201204_1	1380390.JIAT01000017_gene5297	6.943e-92	308.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158188_k127_220161_0	1283299.AUKG01000001_gene2451	5.651e-106	346.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_220161_3	526227.Mesil_3163	2.357e-53	197.0	COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158188_k127_220161_5	1122939.ATUD01000015_gene989	1.15e-43	165.0	COG0778@1|root,COG0778@2|Bacteria,2HRX2@201174|Actinobacteria,4CU07@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158188_k127_220161_7	266117.Rxyl_0142	1.46e-26	123.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4CQIW@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158188_k127_220161_6	1123023.JIAI01000003_gene2566	7.423e-32	133.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_220161_9	795666.MW7_2554	7.509e-15	87.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,1K1YA@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid	livK2	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158188_k127_220161_2	479432.Sros_6001	1.278e-82	285.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4EJ9U@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158188_k127_220161_4	1123499.KB908030_gene608	5.006e-44	183.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,2KPXB@206351|Neisseriales	206351|Neisseriales	E	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158188_k127_220161_1	869210.Marky_1015	2.378e-88	321.0	COG0411@1|root,COG0411@2|Bacteria,1WJG8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158188_k127_220161_8	327277.JHAL01000002_gene1076	4.636e-18	96.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158188_k127_2205310_7	1123269.NX02_27255	5.207e-05	56.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,2V1PT@28211|Alphaproteobacteria,2K8V0@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158188_k127_2205310_6	1460635.JCM19038_3652	2.199e-18	91.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158188_k127_2205310_0	469383.Cwoe_5909	1.46e-147	481.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4CPJV@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase, family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158188_k127_2205310_2	644282.Deba_0457	1.151e-41	160.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158188_k127_2205310_4	298655.KI912266_gene1786	1.803e-39	160.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4ESU1@85013|Frankiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
SRR25158188_k127_2205310_1	1121087.AUCK01000001_gene2990	1.695e-77	272.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,4HAGP@91061|Bacilli,1ZEGY@1386|Bacillus	91061|Bacilli	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158188_k127_2205310_3	693661.Arcve_1373	1.222e-40	157.0	COG1131@1|root,arCOG00194@2157|Archaea,2XXA3@28890|Euryarchaeota,2467K@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158188_k127_2205310_5	445975.COLSTE_02258	9.2e-31	136.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria,4CV8U@84998|Coriobacteriia	84998|Coriobacteriia	O	heme exporter protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158188_k127_2212694_1	1380390.JIAT01000010_gene4506	1.527e-111	369.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CPR4@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158188_k127_2212694_2	1187851.A33M_2337	6.707e-76	265.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,2U7N6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158188_k127_2212694_3	479431.Namu_0023	1.595e-32	140.0	2BG65@1|root,32A2Y@2|Bacteria,2IRVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2212694_4	1396418.BATQ01000171_gene2901	2.993e-20	91.0	COG0662@1|root,COG0662@2|Bacteria,46VA6@74201|Verrucomicrobia,2IVWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2212694_0	515635.Dtur_0594	1.344e-112	374.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158188_k127_2221970_0	1267535.KB906767_gene721	4.964e-58	218.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158188_k127_2221970_2	1267535.KB906767_gene722	1.292e-32	134.0	COG1006@1|root,COG1006@2|Bacteria	2|Bacteria	P	Multisubunit Na H antiporter MnhC subunit	mrpC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
SRR25158188_k127_2221970_1	1449353.JQMQ01000005_gene4674	1.072e-39	157.0	COG2111@1|root,COG2111@2|Bacteria,2GMI3@201174|Actinobacteria,2NG5B@228398|Streptacidiphilus	201174|Actinobacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	mrpB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
SRR25158188_k127_2221970_3	1463854.JOHT01000009_gene1504	4.244e-08	61.0	2DT50@1|root,33IQQ@2|Bacteria,2GRGN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040
SRR25158188_k127_2221970_4	1268635.Loa_01686	3.62e-06	54.0	290W6@1|root,2ZNI0@2|Bacteria	2|Bacteria	S	Na+/H+ antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
SRR25158188_k127_2237546_1	709797.CSIRO_1435	5.131e-42	158.0	COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,2TVKT@28211|Alphaproteobacteria,3JSJG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_18605	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158188_k127_2237546_0	1380394.JADL01000002_gene1158	1.428e-60	226.0	COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2TUBF@28211|Alphaproteobacteria,2JUXE@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158188_k127_2237546_2	1297865.APJD01000036_gene1466	4.597e-32	131.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2U207@28211|Alphaproteobacteria,3JXM6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158188_k127_2242870_1	1108045.GORHZ_137_00230	8.621e-38	162.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158188_k127_2242870_0	266117.Rxyl_2032	5.679e-43	178.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CPCG@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158188_k127_2242870_2	546271.Selsp_0309	0.0007338	47.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4H5GX@909932|Negativicutes	909932|Negativicutes	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158188_k127_2252140_2	314278.NB231_04660	2.828e-17	84.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria	1224|Proteobacteria	C	maturation	vhtD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158188_k127_2252140_5	318424.EU78_10630	7.628e-07	57.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,239ZW@1762|Mycobacteriaceae	201174|Actinobacteria	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158188_k127_2252140_1	351607.Acel_1022	4.002e-83	291.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_2252140_0	351607.Acel_1023	1.21e-90	319.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria,4EVHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2252140_4	469383.Cwoe_2970	2.461e-11	70.0	2EI38@1|root,33BUR@2|Bacteria,2GZ5N@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_226185_2	266117.Rxyl_1108	2.539e-68	247.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158188_k127_226185_0	1068978.AMETH_2302	2.358e-158	520.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4E06F@85010|Pseudonocardiales	201174|Actinobacteria	I	Phospholipase D Active site motif	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
SRR25158188_k127_226185_1	469383.Cwoe_5326	1.985e-71	257.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria,4CPBH@84995|Rubrobacteria	84995|Rubrobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158188_k127_226185_4	235985.BBPN01000012_gene6783	1.349e-11	72.0	COG1366@1|root,COG1366@2|Bacteria,2GT1D@201174|Actinobacteria,2NJ4J@228398|Streptacidiphilus	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158188_k127_226185_3	298655.KI912266_gene17	3.26e-62	226.0	COG1562@1|root,COG1562@2|Bacteria,2GNS9@201174|Actinobacteria,4EV51@85013|Frankiales	201174|Actinobacteria	I	PFAM Squalene phytoene synthase	hopE	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR25158188_k127_226185_5	1449976.KALB_4047	6.247e-11	66.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4E0VU@85010|Pseudonocardiales	201174|Actinobacteria	I	Squalene phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158188_k127_227556_0	1157490.EL26_03435	3.037e-145	473.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,277ZC@186823|Alicyclobacillaceae	91061|Bacilli	P	Ammonium Transporter Family	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158188_k127_227556_4	69279.BG36_00510	5.052e-51	188.0	COG1280@1|root,COG1280@2|Bacteria,1RBIQ@1224|Proteobacteria,2U7PS@28211|Alphaproteobacteria,43KVA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158188_k127_227556_5	234267.Acid_4614	9.346e-46	189.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	ywnH	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158188_k127_227556_3	469383.Cwoe_4474	2.633e-57	209.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	sseA2	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158188_k127_227556_1	118163.Ple7327_2930	6.42e-143	467.0	COG4992@1|root,COG4992@2|Bacteria,1G4MC@1117|Cyanobacteria,3VMJX@52604|Pleurocapsales	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158188_k127_227556_6	1120948.KB903247_gene4516	6.429e-42	161.0	COG2259@1|root,COG2259@2|Bacteria,2IQ5C@201174|Actinobacteria,4E7BI@85010|Pseudonocardiales	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158188_k127_227556_7	1120950.KB892827_gene641	4.659e-31	126.0	2DGHS@1|root,2ZW1B@2|Bacteria,2H7G7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_227556_2	1283299.AUKG01000001_gene1347	2.129e-82	282.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CRQ1@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158188_k127_2304682_1	397278.JOJN01000002_gene639	4.344e-106	347.0	COG5598@1|root,COG5598@2|Bacteria,2HSQ1@201174|Actinobacteria,4DU2E@85009|Propionibacteriales	201174|Actinobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
SRR25158188_k127_2304682_3	1150864.MILUP08_30098	4.339e-19	92.0	COG2905@1|root,COG2905@2|Bacteria,2HUC9@201174|Actinobacteria,4DE72@85008|Micromonosporales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158188_k127_2304682_0	1246995.AFR_16910	1.875e-212	669.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158188_k127_2304682_2	1306174.JODP01000001_gene5296	4.09e-68	236.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158188_k127_2307895_0	997346.HMPREF9374_3070	1.648e-148	481.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,27BMB@186824|Thermoactinomycetaceae	91061|Bacilli	F	Adenylosuccinate lyase C-terminus	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09895	ADSL_C,Lyase_1
SRR25158188_k127_2307895_1	713586.KB900536_gene1677	2.78e-100	338.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales	135613|Chromatiales	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158188_k127_2307895_4	1105367.CG50_11035	2.006e-14	85.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158188_k127_2307895_2	266117.Rxyl_0995	1.409e-71	248.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4CPW1@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158188_k127_2307895_3	1158292.JPOE01000005_gene1000	9.319e-48	177.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	cysP	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306,ko:K16331	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.4	-	-	PHO4
SRR25158188_k127_2314612_6	1463855.JOHV01000037_gene5854	8.751e-36	143.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR
SRR25158188_k127_2314612_7	411467.BACCAP_03552	6.179e-28	123.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,268S9@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158188_k127_2314612_5	469383.Cwoe_3255	8.228e-47	194.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CQW4@84995|Rubrobacteria	84995|Rubrobacteria	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158188_k127_2314612_2	1283299.AUKG01000002_gene5156	4.401e-150	486.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158188_k127_2314612_4	1380347.JNII01000009_gene2269	5.754e-83	281.0	arCOG10607@1|root,30Y0T@2|Bacteria,2I8NG@201174|Actinobacteria,4EWP8@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2314612_0	1380390.JIAT01000010_gene4809	8.429e-160	521.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CS83@84995|Rubrobacteria	84995|Rubrobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158188_k127_2314612_10	1232443.BAIA02000110_gene2584	1.982e-07	60.0	COG2137@1|root,COG2137@2|Bacteria,1VJ1E@1239|Firmicutes,24QUU@186801|Clostridia	186801|Clostridia	S	Modulates RecA activity	recX	-	-	-	-	-	-	-	-	-	-	-	RecX
SRR25158188_k127_2314612_1	1380390.JIAT01000010_gene4814	1.971e-151	486.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158188_k127_2314612_8	929712.KI912613_gene2255	1.355e-16	92.0	COG1514@1|root,COG1514@2|Bacteria,2HNKJ@201174|Actinobacteria,4CQT5@84995|Rubrobacteria	84995|Rubrobacteria	J	LigT like Phosphoesterase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158188_k127_2314612_3	1380356.JNIK01000006_gene1496	2.154e-87	310.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158188_k127_2314612_9	1089553.Tph_c11520	1.779e-16	88.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,42J4X@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158188_k127_2320006_0	555088.DealDRAFT_0872	1.66e-76	265.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158188_k127_2320006_1	768704.Desmer_3712	6.526e-68	239.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,261P1@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2334681_2	55952.BU52_32620	2.029e-85	292.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	appCC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158188_k127_2334681_0	1146883.BLASA_0481	6.968e-132	428.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4ETRM@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_2334681_1	471853.Bcav_2197	1.092e-130	441.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_2334681_3	929712.KI912613_gene2824	1.1e-26	113.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_2335024_1	1449976.KALB_216	2.677e-14	85.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E2KG@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_2335024_0	290399.Arth_0636	1.504e-115	375.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158188_k127_2339311_2	263358.VAB18032_06315	2.714e-08	61.0	COG0457@1|root,COG0457@2|Bacteria,2IHX2@201174|Actinobacteria,4DJR3@85008|Micromonosporales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2339311_1	1150864.MILUP08_44673	9.803e-90	303.0	COG3340@1|root,COG3340@2|Bacteria,2GMIV@201174|Actinobacteria,4D9N5@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158188_k127_2339311_0	1283299.AUKG01000001_gene2027	9.903e-225	714.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4CPU9@84995|Rubrobacteria	84995|Rubrobacteria	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158188_k127_235823_1	266117.Rxyl_2066	4.164e-46	178.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4CQDA@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158188_k127_235823_2	1303692.SFUL_601	2.958e-23	115.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria	201174|Actinobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_235823_0	36809.MAB_3909	1.331e-253	796.0	COG2373@1|root,COG2373@2|Bacteria,2H4M3@201174|Actinobacteria,236MB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Catalase
SRR25158188_k127_2382958_1	105420.BBPO01000032_gene6545	3.479e-26	109.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,2NFKX@228398|Streptacidiphilus	201174|Actinobacteria	J	Seryl-tRNA synthetase N-terminal domain	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158188_k127_2382958_2	1530186.JQEY01000001_gene893	4.838e-07	58.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158188_k127_2382958_0	216594.MMAR_0936	0.0	1219.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,23C6I@1762|Mycobacteriaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158188_k127_2402823_0	1128421.JAGA01000002_gene1751	1.693e-136	445.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158188_k127_2402823_5	867902.Ornrh_2110	7.503e-49	191.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158188_k127_2402823_3	1521187.JPIM01000074_gene2857	3.278e-68	242.0	COG0491@1|root,COG0491@2|Bacteria,2G6KC@200795|Chloroflexi,376B0@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_2402823_2	103733.JNYO01000030_gene1387	2.59e-68	248.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4E01T@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_2402823_6	1079986.JH164859_gene7691	4.802e-42	159.0	COG3467@1|root,COG3467@2|Bacteria,2IIWQ@201174|Actinobacteria	201174|Actinobacteria	S	F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158188_k127_2402823_4	1123321.KB905815_gene3406	1.844e-50	199.0	COG0223@1|root,COG0223@2|Bacteria,2IH1J@201174|Actinobacteria	201174|Actinobacteria	J	Formyl transferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158188_k127_2402823_1	1120972.AUMH01000009_gene459	3.559e-69	243.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,278V8@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158188_k127_2402823_8	446470.Snas_5846	0.0009174	44.0	COG0237@1|root,COG0237@2|Bacteria,2IDI7@201174|Actinobacteria	201174|Actinobacteria	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2422329_0	867903.ThesuDRAFT_01390	1.834e-138	452.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158188_k127_2422329_5	1089545.KB913037_gene7386	1.983e-13	79.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158188_k127_2422329_2	469383.Cwoe_2188	4.123e-65	235.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158188_k127_2422329_7	1382304.JNIL01000001_gene2578	4.682e-05	47.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158188_k127_2422329_6	436229.JOEH01000006_gene2938	1.006e-05	55.0	COG0664@1|root,COG0664@2|Bacteria,2ID3H@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158188_k127_2422329_1	330084.JNYZ01000008_gene6648	5.273e-131	442.0	COG1506@1|root,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DYU4@85010|Pseudonocardiales	201174|Actinobacteria	EV	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158188_k127_2422329_3	479434.Sthe_2570	4.06e-48	183.0	COG2151@1|root,COG2151@2|Bacteria,2G9PR@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158188_k127_2422329_4	745776.DGo_CA2891	1.472e-37	149.0	COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158188_k127_2424527_1	591167.Sfla_0017	3.346e-61	226.0	COG0477@1|root,COG2814@2|Bacteria,2I3AN@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_2424527_2	1380390.JIAT01000015_gene5878	1.57e-39	159.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria	201174|Actinobacteria	D	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158188_k127_2424527_4	105420.BBPO01000004_gene1436	1.019e-30	126.0	arCOG03092@1|root,32YMQ@2|Bacteria,2I3JS@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158188_k127_2424527_5	105420.BBPO01000004_gene1436	3.706e-30	123.0	arCOG03092@1|root,32YMQ@2|Bacteria,2I3JS@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158188_k127_2424527_8	1120950.KB892746_gene3526	1.085e-24	113.0	COG0154@1|root,COG0154@2|Bacteria,2GNCS@201174|Actinobacteria,4DS5R@85009|Propionibacteriales	201174|Actinobacteria	J	Gas vesicle synthesis protein GvpL/GvpF	gvpF	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158188_k127_2424527_12	1169161.KB897730_gene1044	2.633e-12	70.0	2E38Y@1|root,32Y8N@2|Bacteria	2|Bacteria	S	Gas vesicle protein G	gvpG	-	-	-	-	-	-	-	-	-	-	-	GvpG
SRR25158188_k127_2424527_10	446468.Ndas_2357	1.263e-14	83.0	arCOG04040@1|root,334QT@2|Bacteria,2GQNG@201174|Actinobacteria,4EKPW@85012|Streptosporangiales	201174|Actinobacteria	S	Gas vesicle synthesis protein GvpO	-	-	-	-	-	-	-	-	-	-	-	-	GvpO
SRR25158188_k127_2424527_7	1157640.AQWO01000011_gene3274	1.048e-26	117.0	2E5BC@1|root,3303G@2|Bacteria,2IR3J@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158188_k127_2424527_3	1380390.JIAT01000015_gene5872	1.389e-38	162.0	2DM5J@1|root,31T6B@2|Bacteria,2GMP8@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicle	gvpL2	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158188_k127_2424527_13	319225.Plut_0704	2.483e-11	69.0	2DRDP@1|root,33BB6@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpS1	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158188_k127_2424527_9	1380390.JIAT01000015_gene5870	2.28e-17	95.0	2CK1D@1|root,2ZAG7@2|Bacteria	2|Bacteria	S	Gas vesicle synthesis protein GvpL/GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158188_k127_2424527_6	1380390.JIAT01000015_gene5869	3.295e-27	120.0	arCOG06390@1|root,330IR@2|Bacteria,2IQAU@201174|Actinobacteria	201174|Actinobacteria	S	Gas vesicle	gvpK	-	-	-	-	-	-	-	-	-	-	-	GvpK
SRR25158188_k127_2424527_11	1227495.C487_14959	3.191e-13	76.0	arCOG02998@1|root,arCOG02998@2157|Archaea,2XX29@28890|Euryarchaeota,23VR4@183963|Halobacteria	183963|Halobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2424527_0	1489678.RDMS_02100	1.838e-139	456.0	COG1866@1|root,COG1866@2|Bacteria,1WIQ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158188_k127_2435513_3	397278.JOJN01000002_gene465	5.317e-31	135.0	COG3629@1|root,COG3629@2|Bacteria,2IP3I@201174|Actinobacteria	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Response_reg,Trans_reg_C
SRR25158188_k127_2435513_2	469383.Cwoe_2962	3.58e-33	134.0	COG4315@1|root,COG4315@2|Bacteria	2|Bacteria	P	Pfam Secreted repeat of	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158188_k127_2435513_0	345341.KUTG_09190	1.314e-142	466.0	28JCT@1|root,2Z97C@2|Bacteria,2H72Y@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2435513_4	146922.JOFU01000001_gene557	8.871e-30	128.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	azr	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158188_k127_2435513_1	1123023.JIAI01000003_gene2782	2.09e-51	190.0	COG2353@1|root,COG2353@2|Bacteria,2H5SM@201174|Actinobacteria	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158188_k127_2435513_5	469383.Cwoe_5357	4.932e-11	69.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4CQI6@84995|Rubrobacteria	84995|Rubrobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158188_k127_2440654_1	266117.Rxyl_2133	2.241e-91	306.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CPA2@84995|Rubrobacteria	84995|Rubrobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158188_k127_2440654_5	907348.TresaDRAFT_0918	3.894e-27	111.0	COG0361@1|root,COG0361@2|Bacteria,2J8JW@203691|Spirochaetes	203691|Spirochaetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158188_k127_2440654_6	469383.Cwoe_1363	1.497e-14	73.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158188_k127_2440654_4	868595.Desca_0237	1.01e-49	179.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,261QX@186807|Peptococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158188_k127_2440654_3	469383.Cwoe_1365	6.622e-64	222.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CPZ7@84995|Rubrobacteria	84995|Rubrobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158188_k127_2440654_2	1283299.AUKG01000001_gene2657	2.454e-89	300.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CQ5S@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158188_k127_2440654_0	469383.Cwoe_1366	5.917e-92	307.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158188_k127_2440998_6	526225.Gobs_1039	5.053e-24	102.0	COG2021@1|root,COG2021@2|Bacteria,2I3EQ@201174|Actinobacteria	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158188_k127_2440998_0	469383.Cwoe_4554	3.701e-96	327.0	COG3294@1|root,COG3294@2|Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158188_k127_2440998_5	469383.Cwoe_3402	3.966e-30	128.0	2B412@1|root,31WRB@2|Bacteria,2HY97@201174|Actinobacteria,4CQGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2440998_4	479434.Sthe_2063	1.238e-42	164.0	COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158188_k127_2440998_3	1380390.JIAT01000014_gene6280	1.742e-53	209.0	COG0500@1|root,COG2226@2|Bacteria,2HQDN@201174|Actinobacteria,4CRY5@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_2440998_2	1380390.JIAT01000017_gene5312	3.547e-64	231.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CPTU@84995|Rubrobacteria	84995|Rubrobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158188_k127_2440998_1	1051632.TPY_0095	4.776e-65	229.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,3WCEP@538999|Clostridiales incertae sedis	186801|Clostridia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158188_k127_2468529_1	196162.Noca_1686	5.885e-06	53.0	2BBSN@1|root,325AU@2|Bacteria,2HAF6@201174|Actinobacteria,4DW9U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2468529_2	1236976.JCM16418_1668	0.0001581	52.0	COG1409@1|root,COG2356@1|root,COG3420@1|root,COG1409@2|Bacteria,COG2356@2|Bacteria,COG3420@2|Bacteria,1VUKQ@1239|Firmicutes,4I6YF@91061|Bacilli,26VI8@186822|Paenibacillaceae	91061|Bacilli	P	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2468529_0	397278.JOJN01000003_gene1954	1.66e-21	101.0	COG0681@1|root,COG0681@2|Bacteria,2GX48@201174|Actinobacteria,4DTQ3@85009|Propionibacteriales	201174|Actinobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158188_k127_2494259_3	709986.Deima_1398	2.633e-13	73.0	COG0563@1|root,COG0563@2|Bacteria,1WMN6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2494259_4	196162.Noca_3424	0.0002637	53.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4DN0W@85009|Propionibacteriales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
SRR25158188_k127_2494259_1	700508.D174_19260	3.966e-39	162.0	COG0524@1|root,COG0524@2|Bacteria,2GP2R@201174|Actinobacteria,234MH@1762|Mycobacteriaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158188_k127_2494259_0	357808.RoseRS_2771	1.909e-89	316.0	COG1457@1|root,COG1457@2|Bacteria,2G9KC@200795|Chloroflexi,376PN@32061|Chloroflexia	32061|Chloroflexia	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
SRR25158188_k127_2494259_2	469383.Cwoe_3353	7.976e-25	114.0	2BN7C@1|root,32GUQ@2|Bacteria,2HRTT@201174|Actinobacteria,4CTX6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2495685_0	357808.RoseRS_3926	2.961e-78	286.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,377Z7@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158188_k127_2495685_1	105425.BBPL01000052_gene5734	1.847e-69	248.0	COG0388@1|root,COG0388@2|Bacteria,2GP6F@201174|Actinobacteria,2NF26@228398|Streptacidiphilus	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158188_k127_249837_0	196162.Noca_1678	2.689e-112	372.0	COG0558@1|root,COG0558@2|Bacteria,2I5BP@201174|Actinobacteria,4DPS9@85009|Propionibacteriales	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf,Sulfatase
SRR25158188_k127_249837_1	391037.Sare_2747	8.205e-89	304.0	COG0807@1|root,COG0807@2|Bacteria,2GNS4@201174|Actinobacteria,4DAAG@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N,GTP_cyclohydro2
SRR25158188_k127_249837_2	1298863.AUEP01000004_gene1933	4.894e-57	201.0	COG1985@1|root,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4DQ6V@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	ribG	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158188_k127_2521682_4	1463921.JODF01000002_gene3096	1.098e-101	365.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
SRR25158188_k127_2521682_1	1449976.KALB_3320	3.786e-171	550.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4DZR1@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
SRR25158188_k127_2521682_9	391625.PPSIR1_01192	0.0003381	48.0	2ANI1@1|root,31DGW@2|Bacteria,1QARK@1224|Proteobacteria,43E3E@68525|delta/epsilon subdivisions,2WZKG@28221|Deltaproteobacteria,2Z2BA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2521682_3	479434.Sthe_1415	2.748e-143	485.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,27Y17@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158188_k127_2521682_7	882.DVU_1051	1.554e-05	54.0	COG2332@1|root,COG2332@2|Bacteria,1PZFU@1224|Proteobacteria,42U7H@68525|delta/epsilon subdivisions,2WQ19@28221|Deltaproteobacteria,2MC51@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158188_k127_2521682_5	374847.Kcr_0075	6.845e-18	93.0	COG0648@1|root,arCOG01894@2157|Archaea	2157|Archaea	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158188_k127_2521682_2	469383.Cwoe_3174	1.746e-158	511.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158188_k127_2521682_6	1226994.AMZB01000127_gene3942	3.098e-16	91.0	COG0824@1|root,COG0824@2|Bacteria,1N4X2@1224|Proteobacteria,1SYCD@1236|Gammaproteobacteria,1YG72@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158188_k127_2521682_0	469383.Cwoe_3187	2.422e-217	687.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158188_k127_2521682_8	1121091.AUMP01000002_gene1934	6.179e-05	45.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158188_k127_2548509_0	1283299.AUKG01000001_gene3557	2.969e-176	573.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,2GKVH@201174|Actinobacteria,4CRRI@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3
SRR25158188_k127_2548509_1	864051.BurJ1DRAFT_3461	6.675e-18	91.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158188_k127_2550275_3	278963.ATWD01000001_gene3712	3.836e-12	74.0	COG1587@1|root,COG2203@1|root,COG1587@2|Bacteria,COG2203@2|Bacteria,3Y68Z@57723|Acidobacteria,2JK7D@204432|Acidobacteriia	204432|Acidobacteriia	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2,HEM4
SRR25158188_k127_2550275_1	345341.KUTG_01015	3.277e-85	295.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4ECUV@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Sodium calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158188_k127_2550275_0	1385518.N798_16405	4.217e-105	351.0	COG0664@1|root,COG0664@2|Bacteria,2ID3H@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158188_k127_2550275_2	929712.KI912613_gene3063	7.109e-55	194.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158188_k127_2556048_2	316274.Haur_0105	3.436e-113	372.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158188_k127_2556048_5	309801.trd_A0395	1.141e-76	282.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158188_k127_2556048_7	1111479.AXAR01000004_gene2056	5.321e-67	246.0	COG0154@1|root,COG0154@2|Bacteria,1TR9X@1239|Firmicutes,4HAYP@91061|Bacilli,27AQ0@186823|Alicyclobacillaceae	91061|Bacilli	J	Amidase	gatA3	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158188_k127_2556048_9	266117.Rxyl_0052	2.352e-17	96.0	COG3429@1|root,COG3429@2|Bacteria,2HYJH@201174|Actinobacteria,4CPZH@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158188_k127_2556048_0	1521187.JPIM01000002_gene3134	9.989e-171	560.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158188_k127_2556048_1	404589.Anae109_0596	1.48e-138	452.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	6-phosphogluconate dehydrogenase (decarboxylating)	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2620	6PGD,NAD_binding_2
SRR25158188_k127_2556048_4	314278.NB231_09548	1.912e-112	380.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRR25158188_k127_2556048_3	547163.BN979_02792	4.62e-113	377.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,236CP@1762|Mycobacteriaceae	201174|Actinobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158188_k127_2556048_8	926569.ANT_18070	1.151e-44	174.0	COG0698@1|root,COG0698@2|Bacteria,2G6SM@200795|Chloroflexi	200795|Chloroflexi	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158188_k127_2556048_6	1906.SFRA_05420	5.959e-71	243.0	COG0021@1|root,COG0021@2|Bacteria,2I36F@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the transketolase family	tkt3	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158188_k127_2575017_3	1120917.AQXM01000061_gene1850	7.501e-09	67.0	COG1670@1|root,COG1670@2|Bacteria,2IP23@201174|Actinobacteria,1W9IV@1268|Micrococcaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_2575017_2	1172180.KB911797_gene7994	1.693e-65	246.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria	201174|Actinobacteria	J	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158188_k127_2575017_0	266117.Rxyl_0406	2.702e-77	276.0	COG0842@1|root,COG0842@2|Bacteria,2GSKI@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_2575017_1	479434.Sthe_0693	7.573e-76	260.0	COG1131@1|root,COG1131@2|Bacteria,2G5YX@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_2575610_0	981369.JQMJ01000004_gene1339	4.57e-201	650.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,2NGX8@228398|Streptacidiphilus	201174|Actinobacteria	E	GMC oxidoreductase	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158188_k127_2575610_1	285514.JNWO01000007_gene3509	2.559e-78	278.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158188_k127_2575610_2	748247.AZKH_p0144	4.308e-70	240.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria	1224|Proteobacteria	H	trimethylamine methyltransferase	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
SRR25158188_k127_258837_3	28564.XP_002479549.1	1.045e-12	80.0	29CBJ@1|root,2RJF6@2759|Eukaryota,3A0CA@33154|Opisthokonta,3P1Z5@4751|Fungi,3QVY2@4890|Ascomycota,20H0Z@147545|Eurotiomycetes,3S8SQ@5042|Eurotiales	4751|Fungi	S	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
SRR25158188_k127_258837_1	1122182.KB903838_gene4184	4.88e-85	292.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,4DCXD@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_258837_0	1123023.JIAI01000010_gene8666	1.196e-114	385.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DYWA@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_258837_2	1348663.KCH_12330	2.275e-50	192.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,2M4YS@2063|Kitasatospora	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158188_k127_259593_2	1283299.AUKG01000005_gene41	7.618e-30	122.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158188_k127_259593_3	1380390.JIAT01000010_gene4817	7.43e-25	113.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SRR25158188_k127_259593_0	1048339.KB913029_gene2282	3.837e-62	233.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4EUF4@85013|Frankiales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158188_k127_259593_1	1123322.KB904702_gene158	2.319e-38	149.0	COG3402@1|root,COG3402@2|Bacteria,2IR88@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158188_k127_2597895_1	35754.JNYJ01000008_gene3192	2.46e-50	192.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DAC4@85008|Micromonosporales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158188_k127_2597895_2	868595.Desca_2306	5.54e-30	125.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2597895_0	383372.Rcas_4343	7.017e-64	240.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
SRR25158188_k127_2622121_2	477641.MODMU_4504	3.005e-74	267.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4ES21@85013|Frankiales	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158188_k127_2622121_3	1408418.JNJH01000067_gene754	2.04e-61	233.0	COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,2TUA3@28211|Alphaproteobacteria,2JSSN@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158188_k127_2622121_1	1367847.JCM7686_0188	2.149e-93	317.0	COG4132@1|root,COG4132@2|Bacteria,1NF20@1224|Proteobacteria,2U0S4@28211|Alphaproteobacteria,2PVG3@265|Paracoccus	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158188_k127_2622121_0	526227.Mesil_3326	4.006e-111	372.0	COG1840@1|root,COG1840@2|Bacteria,1WKAV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
SRR25158188_k127_26281_0	1128421.JAGA01000003_gene3158	2.003e-141	456.0	COG1260@1|root,COG1260@2|Bacteria,2NNVE@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158188_k127_26281_2	469383.Cwoe_0791	2.26e-38	155.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158188_k127_26281_4	863239.AFIZ01000013_gene1193	2.467e-25	122.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,22MM5@1653|Corynebacteriaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158188_k127_26281_1	1121952.ATXT01000014_gene1443	1.23e-137	447.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4FKNS@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158188_k127_26281_3	1370122.JHXQ01000002_gene2705	1.428e-31	126.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,4B80H@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158188_k127_265229_0	1122939.ATUD01000025_gene2546	1.543e-118	390.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158188_k127_265229_4	1380393.JHVP01000002_gene1698	0.0002776	49.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4ESMP@85013|Frankiales	201174|Actinobacteria	K	TIGRFAM cell envelope-related function transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158188_k127_265229_2	593907.Celgi_0313	7.183e-53	198.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4F26H@85016|Cellulomonadaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
SRR25158188_k127_265229_3	357808.RoseRS_3588	4.119e-37	155.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,37807@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA polymerase III, delta prime subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158188_k127_265229_1	929712.KI912613_gene2824	5.318e-74	261.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_2678664_10	1828.JOKB01000067_gene3590	2.859e-07	51.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4FU09@85025|Nocardiaceae	201174|Actinobacteria	C	FMN-dependent dehydrogenase	lldD2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
SRR25158188_k127_2678664_5	28444.JODQ01000007_gene6033	4.408e-63	235.0	COG1028@1|root,COG1028@2|Bacteria,2HP88@201174|Actinobacteria,4EPJZ@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158188_k127_2678664_0	28444.JODQ01000007_gene6032	4.911e-105	364.0	COG2124@1|root,COG2124@2|Bacteria,2HEJ4@201174|Actinobacteria,4ENWH@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158188_k127_2678664_6	1150864.MILUP08_30153	8.493e-44	177.0	COG1506@1|root,COG1506@2|Bacteria,2I3Z4@201174|Actinobacteria,4DCIS@85008|Micromonosporales	201174|Actinobacteria	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6,Peptidase_S9
SRR25158188_k127_2678664_8	1121929.KB898662_gene479	1.229e-29	129.0	COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HFT9@91061|Bacilli	91061|Bacilli	Q	isochorismatase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158188_k127_2678664_3	2002.JOEQ01000011_gene3864	1.536e-67	243.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158188_k127_2678664_4	1205683.CAKR01000020_gene3125	3.666e-63	230.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,1T0VK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	4.1.1.52	ko:K07045,ko:K22213	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_2
SRR25158188_k127_2678664_9	83219.PM02_05785	8.901e-27	125.0	COG1414@1|root,COG1414@2|Bacteria,1R5ZB@1224|Proteobacteria,2TUN3@28211|Alphaproteobacteria,3ZVIN@60136|Sulfitobacter	28211|Alphaproteobacteria	K	Bacterial transcriptional regulator	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158188_k127_2678664_2	1123320.KB889711_gene8513	1.313e-72	256.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158188_k127_2678664_1	28444.JODQ01000007_gene6037	1.171e-98	329.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EJBR@85012|Streptosporangiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158188_k127_2678664_7	1123023.JIAI01000001_gene7667	2.521e-31	140.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	MA20_23375	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45,SprT-like
SRR25158188_k127_2678664_11	2074.JNYD01000024_gene2841	9.839e-06	48.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4DYD1@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158188_k127_2688012_0	357808.RoseRS_3816	5.472e-37	154.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G87Y@200795|Chloroflexi,376D4@32061|Chloroflexia	32061|Chloroflexia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_8
SRR25158188_k127_2694821_5	1380390.JIAT01000011_gene2352	1.21e-17	83.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4CRKR@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158188_k127_2694821_0	1380390.JIAT01000011_gene2344	1.674e-222	698.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CR38@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158188_k127_2694821_2	477641.MODMU_1839	6.05e-82	281.0	2C3WA@1|root,2Z8P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2694821_4	351607.Acel_1463	2.589e-47	193.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4ET71@85013|Frankiales	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2694821_1	351607.Acel_0233	6.953e-111	371.0	COG3391@1|root,COG3391@2|Bacteria,2I1IX@201174|Actinobacteria,4EVVE@85013|Frankiales	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4114,Lactonase,Phage-tail_3
SRR25158188_k127_2694821_3	469383.Cwoe_2408	3.17e-80	274.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158188_k127_2698151_0	700508.D174_16660	3.937e-52	205.0	COG0687@1|root,COG0687@2|Bacteria,2HQAG@201174|Actinobacteria,236G3@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
SRR25158188_k127_2698151_1	1343740.M271_46725	6.431e-52	191.0	COG1396@1|root,COG1396@2|Bacteria,2GN2U@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158188_k127_2698151_2	1525715.IX54_04705	1.588e-46	170.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2UAPG@28211|Alphaproteobacteria,2PX1V@265|Paracoccus	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_2698151_3	1051632.TPY_1667	3.244e-14	76.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WCDK@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_2699016_2	330214.NIDE3081	3.019e-20	93.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158188_k127_2699016_1	1283299.AUKG01000001_gene1481	1.59e-94	319.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria,4CPC5@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158188_k127_2699016_0	591158.SSMG_02059	1.716e-147	481.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158188_k127_2708306_0	1380390.JIAT01000002_gene5986	3.597e-229	733.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CPR8@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158188_k127_2708306_5	1306990.BARG01000052_gene6122	5.559e-27	122.0	COG1802@1|root,COG1802@2|Bacteria,2GMI2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158188_k127_2708306_2	469371.Tbis_1139	2.293e-193	622.0	COG2225@1|root,COG2225@2|Bacteria,2GJGP@201174|Actinobacteria,4DY8N@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158188_k127_2708306_1	867903.ThesuDRAFT_01087	2.032e-204	644.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes	1239|Firmicutes	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158188_k127_2708306_3	1463885.KL578445_gene162	1.153e-44	169.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158188_k127_2708306_4	469383.Cwoe_2649	2.883e-35	136.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158188_k127_2721512_2	485914.Hmuk_0750	7.586e-82	279.0	arCOG06337@1|root,arCOG06337@2157|Archaea,2XTXK@28890|Euryarchaeota,23SF3@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2721512_6	1122939.ATUD01000001_gene585	4.571e-26	121.0	COG3837@1|root,COG3837@2|Bacteria,2HR5Z@201174|Actinobacteria,4CT1K@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2721512_4	1227487.C474_11246	6.347e-29	127.0	arCOG02998@1|root,arCOG02998@2157|Archaea,2XX29@28890|Euryarchaeota,23VR4@183963|Halobacteria	183963|Halobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2721512_0	1229780.BN381_80228	2.206e-163	523.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX43@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_2721512_1	1283299.AUKG01000001_gene2897	4.227e-141	458.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CRMB@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_2721512_8	1054213.HMPREF9946_00229	8.142e-21	98.0	COG0662@1|root,COG0662@2|Bacteria,1RHN1@1224|Proteobacteria,2U8E9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2721512_9	479431.Namu_1845	9.795e-18	89.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4ET44@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158188_k127_2721512_5	42256.RradSPS_2058	1.641e-27	117.0	COG0824@1|root,COG0824@2|Bacteria,2IINH@201174|Actinobacteria,4CQTD@84995|Rubrobacteria	84995|Rubrobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158188_k127_2721512_7	1123023.JIAI01000005_gene623	2.103e-25	122.0	COG5373@1|root,COG5373@2|Bacteria,2GJII@201174|Actinobacteria,4DYXP@85010|Pseudonocardiales	201174|Actinobacteria	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158188_k127_2721512_3	1121439.dsat_2409	4.047e-40	151.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42R4A@68525|delta/epsilon subdivisions,2WM9Z@28221|Deltaproteobacteria,2M9TM@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM Silent information regulator protein Sir2	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158188_k127_2721583_7	1449976.KALB_7029	1.057e-26	110.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria,4DXIP@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158188_k127_2721583_1	1120936.KB907221_gene2228	4.321e-101	341.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4EHKX@85012|Streptosporangiales	201174|Actinobacteria	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158188_k127_2721583_4	479433.Caci_8853	2.458e-70	263.0	COG1120@1|root,COG1120@2|Bacteria,2IA4F@201174|Actinobacteria	201174|Actinobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158188_k127_2721583_0	1463936.JOJI01000012_gene6355	3.292e-109	368.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158188_k127_2721583_5	1227487.C474_11526	1.296e-39	162.0	COG1058@1|root,arCOG00215@2157|Archaea,2XTUT@28890|Euryarchaeota,23SC7@183963|Halobacteria	183963|Halobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	cinA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158188_k127_2721583_6	43759.JNWK01000013_gene6440	2.709e-35	142.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158188_k127_2721583_3	1380390.JIAT01000010_gene4680	2.128e-72	255.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CRGJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158188_k127_2721583_2	266117.Rxyl_2871	4.878e-76	271.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
SRR25158188_k127_2723387_6	931277.C448_13506	4.622e-13	75.0	arCOG06337@1|root,arCOG06337@2157|Archaea,2XTXK@28890|Euryarchaeota,23SF3@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2723387_1	1068980.ARVW01000001_gene4698	8.944e-121	404.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158188_k127_2723387_4	1380390.JIAT01000011_gene2726	1.696e-42	163.0	COG1309@1|root,COG1309@2|Bacteria,2IEV2@201174|Actinobacteria,4CPWP@84995|Rubrobacteria	84995|Rubrobacteria	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
SRR25158188_k127_2723387_0	351607.Acel_1156	3.119e-128	416.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4ERTI@85013|Frankiales	201174|Actinobacteria	O	PFAM Band 7 protein	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158188_k127_2723387_5	471852.Tcur_4808	3.221e-30	124.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,4EJNJ@85012|Streptosporangiales	201174|Actinobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158188_k127_2723387_2	309801.trd_1267	2.511e-84	295.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158188_k127_2723387_3	42256.RradSPS_0262	9.967e-73	249.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4CPJF@84995|Rubrobacteria	84995|Rubrobacteria	O	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158188_k127_2724961_1	1382306.JNIM01000001_gene2570	1.627e-107	351.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158188_k127_2724961_4	1380390.JIAT01000009_gene1809	1.172e-30	136.0	COG5650@1|root,COG5650@2|Bacteria,2HYCN@201174|Actinobacteria,4CQKH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158188_k127_2724961_0	479434.Sthe_3502	4.093e-113	386.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	2|Bacteria	C	Proline dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158188_k127_2724961_6	1158604.I591_01861	3.255e-20	103.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,4AZV3@81852|Enterococcaceae	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158188_k127_2724961_2	331869.BAL199_29480	3.346e-61	225.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,4BQ41@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158188_k127_2724961_5	1050202.KB913024_gene2334	8.377e-29	120.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4091W@622450|Actinopolysporales	201174|Actinobacteria	P	Ferric uptake regulator family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158188_k127_2724961_3	1122604.JONR01000023_gene4137	2.687e-37	153.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	ko:K07238,ko:K11021	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.5	-	-	Zip
SRR25158188_k127_2724961_7	455632.SGR_3153	1.027e-08	65.0	COG0662@1|root,COG0662@2|Bacteria,2IQE7@201174|Actinobacteria,41AZG@629295|Streptomyces griseus group	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2731048_0	1379698.RBG1_1C00001G0474	2.675e-68	251.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158188_k127_2731048_2	1380390.JIAT01000010_gene4524	2.707e-49	188.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158188_k127_2731048_3	469383.Cwoe_3523	1.745e-47	177.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158188_k127_2731048_1	1380390.JIAT01000010_gene4526	2.392e-53	196.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158188_k127_2731048_7	1122939.ATUD01000019_gene1542	5.627e-12	69.0	COG0762@1|root,COG0762@2|Bacteria,2HR5Q@201174|Actinobacteria,4CT15@84995|Rubrobacteria	84995|Rubrobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158188_k127_2731048_8	882.DVU_1373	4.044e-10	68.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WPC4@28221|Deltaproteobacteria,2MBBV@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158188_k127_2731048_5	1269813.ATUL01000020_gene349	1.42e-17	85.0	COG1872@1|root,COG1872@2|Bacteria,1QKJ0@1224|Proteobacteria,1SDPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158188_k127_2731048_4	264732.Moth_0866	2.364e-19	94.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,42FT9@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM sporulation protein, yteA	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158188_k127_2731048_6	469383.Cwoe_3519	4.271e-17	91.0	COG0597@1|root,COG0597@2|Bacteria,2HP4E@201174|Actinobacteria,4CQFY@84995|Rubrobacteria	84995|Rubrobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158188_k127_273933_2	1279017.AQYJ01000028_gene2100	1.906e-36	147.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,465UW@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD,Peptidase_S8
SRR25158188_k127_273933_1	1380356.JNIK01000014_gene3482	8.08e-97	338.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158188_k127_273933_0	1449346.JQMO01000003_gene2483	5.977e-114	374.0	COG4934@1|root,COG4934@2|Bacteria,2GMZ8@201174|Actinobacteria,2M1WV@2063|Kitasatospora	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158188_k127_2749167_9	1184609.KILIM_019_00470	8.964e-09	59.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria	201174|Actinobacteria	I	phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158188_k127_2749167_6	405948.SACE_4329	1.655e-58	222.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria,4E1XZ@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM squalene-associated FAD-dependent desaturase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158188_k127_2749167_0	1348663.KCH_18050	2.149e-195	626.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,2M0Z1@2063|Kitasatospora	201174|Actinobacteria	I	Squalene-hopene cyclase N-terminal domain	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
SRR25158188_k127_2749167_3	575540.Isop_2284	2.629e-103	347.0	COG0535@1|root,COG0535@2|Bacteria,2IWZK@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
SRR25158188_k127_2749167_11	1054213.HMPREF9946_00165	5.54e-08	64.0	COG0775@1|root,COG0775@2|Bacteria,1PETT@1224|Proteobacteria,2TTTB@28211|Alphaproteobacteria,2JU46@204441|Rhodospirillales	204441|Rhodospirillales	F	Phosphorylase superfamily	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158188_k127_2749167_4	1137269.AZWL01000011_gene3202	3.783e-93	317.0	COG0142@1|root,COG0761@1|root,COG0142@2|Bacteria,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,polyprenyl_synt
SRR25158188_k127_2749167_10	517417.Cpar_1695	2.723e-08	62.0	COG0432@1|root,COG0432@2|Bacteria,1FE2S@1090|Chlorobi	1090|Chlorobi	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158188_k127_2749167_5	1463881.KL591002_gene4701	2.581e-75	267.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
SRR25158188_k127_2749167_1	1283299.AUKG01000001_gene1996	5.011e-135	447.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4CPP8@84995|Rubrobacteria	84995|Rubrobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158188_k127_2749167_7	235985.BBPN01000007_gene3429	1.545e-12	79.0	2FB55@1|root,343BG@2|Bacteria,2IKSK@201174|Actinobacteria,2NJ1W@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2749167_2	1206741.BAFX01000118_gene7358	1.821e-132	440.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FX8C@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_2749167_8	1123319.AUBE01000005_gene1	2.599e-11	66.0	COG0451@1|root,COG0451@2|Bacteria,2GJYY@201174|Actinobacteria	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158188_k127_2749829_0	469383.Cwoe_3241	1.618e-188	610.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158188_k127_2749829_1	1283299.AUKG01000002_gene3619	1.681e-87	323.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4CQBS@84995|Rubrobacteria	84995|Rubrobacteria	S	Basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158188_k127_2754173_0	1283299.AUKG01000004_gene1175	7.058e-231	753.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR25158188_k127_2754173_1	1121877.JQKF01000015_gene84	3.08e-23	115.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4CMV3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158188_k127_2754173_3	290399.Arth_0711	1.24e-09	69.0	2BEJ2@1|root,328AC@2|Bacteria,2IH3X@201174|Actinobacteria	201174|Actinobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158188_k127_2754173_4	194867.ALBQ01000025_gene1107	6.388e-09	61.0	2AF64@1|root,3154Z@2|Bacteria,1RJ9E@1224|Proteobacteria,2U9GE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRR25158188_k127_2781126_1	469383.Cwoe_3737	5.549e-36	155.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158188_k127_2781126_4	1121920.AUAU01000005_gene1012	2.291e-09	70.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04092,ko:K04093,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRR25158188_k127_2781126_0	869210.Marky_0686	9.992e-68	235.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158188_k127_2781126_3	134676.ACPL_4029	6.696e-13	76.0	COG0406@1|root,COG0406@2|Bacteria,2IJZ4@201174|Actinobacteria,4D8VC@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158188_k127_2781126_2	1159870.KB907784_gene1022	1.982e-13	75.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,3T49W@506|Alcaligenaceae	28216|Betaproteobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158188_k127_2794282_5	404589.Anae109_1572	5.16e-37	156.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,43AKP@68525|delta/epsilon subdivisions,2X60N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158188_k127_2794282_2	1380390.JIAT01000010_gene4655	2.84e-84	287.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4CU4B@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158188_k127_2794282_3	1380390.JIAT01000010_gene4654	1.474e-58	212.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4CQIG@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158188_k127_2794282_8	929712.KI912613_gene1901	3.172e-26	119.0	COG2452@1|root,COG3585@1|root,COG2452@2|Bacteria,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4CQRP@84995|Rubrobacteria	84995|Rubrobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,TOBE
SRR25158188_k127_2794282_10	5011.R4X8N9	2.981e-07	59.0	29V7Q@1|root,2RXKA@2759|Eukaryota,39TIT@33154|Opisthokonta,3NXZU@4751|Fungi,3QK9M@4890|Ascomycota	4751|Fungi	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158188_k127_2794282_9	1089544.KB912942_gene1530	7.199e-10	64.0	2C4YV@1|root,2ZPNJ@2|Bacteria,2GRAH@201174|Actinobacteria,4EBWF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158188_k127_2794282_4	1192034.CAP_8545	1.667e-39	159.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria,43AS2@68525|delta/epsilon subdivisions,2X666@28221|Deltaproteobacteria,2Z27D@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_2794282_7	1380390.JIAT01000016_gene5483	2.885e-28	119.0	COG0789@1|root,COG0789@2|Bacteria,2HR8S@201174|Actinobacteria,4CT53@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158188_k127_2794282_0	1343740.M271_48120	7.234e-244	768.0	COG0477@1|root,COG0477@2|Bacteria,2GJSC@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_2794282_1	469383.Cwoe_1582	6.548e-106	351.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158188_k127_2794282_6	1429046.RR21198_4556	8.107e-36	143.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4G1CN@85025|Nocardiaceae	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158188_k127_2794282_11	379066.GAU_2712	0.0005346	44.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158188_k127_280202_1	1122939.ATUD01000003_gene3581	7.878e-71	243.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158188_k127_280202_5	1122152.AUEI01000006_gene59	1.966e-31	129.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158188_k127_280202_2	1283299.AUKG01000001_gene2648	1.508e-66	235.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158188_k127_280202_6	1434325.AZQN01000006_gene3365	9.769e-11	66.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158188_k127_280202_4	469383.Cwoe_1359	1.303e-37	150.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158188_k127_280202_0	929712.KI912613_gene4926	7.788e-134	438.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158188_k127_280202_3	331869.BAL199_29650	2.415e-38	163.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,4BQBQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158188_k127_2822470_4	1408473.JHXO01000005_gene1511	4.625e-28	121.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,MerR_1
SRR25158188_k127_2822470_0	1122621.ATZA01000012_gene3116	5.574e-188	612.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158188_k127_2822470_3	555088.DealDRAFT_1118	4.743e-56	206.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,249R4@186801|Clostridia,42JJG@68298|Syntrophomonadaceae	186801|Clostridia	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158188_k127_2822470_5	1123319.AUBE01000012_gene6250	3.074e-07	56.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158188_k127_2822470_1	300852.55773149	2.255e-89	304.0	COG0825@1|root,COG0825@2|Bacteria,1WJ82@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158188_k127_2822470_2	289376.THEYE_A0559	5.755e-76	263.0	COG0777@1|root,COG0777@2|Bacteria,3J0CK@40117|Nitrospirae	40117|Nitrospirae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158188_k127_2834655_0	1297742.A176_01512	2.647e-115	385.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158188_k127_2834655_1	1386089.N865_11755	1.213e-62	237.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4FEFV@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158188_k127_2834655_3	1198452.Jab_1c09840	4.464e-24	115.0	COG1994@1|root,COG1994@2|Bacteria,1PM1Q@1224|Proteobacteria,2VM3E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2834655_2	479434.Sthe_0748	3.985e-49	183.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158188_k127_2834655_4	1382304.JNIL01000001_gene1692	9.59e-14	74.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,27A54@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158188_k127_2840875_4	1396141.BATP01000026_gene1004	8.862e-08	59.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,2ITH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Anthranilate synthase component I, N terminal region	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158188_k127_2840875_2	1220582.RRU01S_25_00080	2.128e-30	129.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,2UFGZ@28211|Alphaproteobacteria,4BETK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
SRR25158188_k127_2840875_1	469383.Cwoe_0999	1.315e-100	338.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158188_k127_2840875_0	867903.ThesuDRAFT_02295	3.516e-134	437.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158188_k127_2840875_3	68194.JNXR01000016_gene7408	2.126e-22	104.0	COG0596@1|root,COG0596@2|Bacteria,2IJXZ@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158188_k127_2843687_0	999549.KI421513_gene2108	2.93e-143	467.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,27ZH3@191028|Leisingera	28211|Alphaproteobacteria	E	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain	gdh	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N,Response_reg
SRR25158188_k127_2843687_5	43759.JNWK01000009_gene5043	2.698e-05	52.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158188_k127_2843687_2	469383.Cwoe_5209	7.097e-54	201.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CPJE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158188_k127_2843687_4	1229780.BN381_130143	7.485e-07	55.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2843687_3	1122939.ATUD01000006_gene1638	1.925e-21	96.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CQCQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158188_k127_2843687_1	1121946.AUAX01000028_gene5814	3.583e-83	280.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DMJF@85008|Micromonosporales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158188_k127_2845362_1	1283299.AUKG01000004_gene1037	2.299e-70	251.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CS7S@84995|Rubrobacteria	84995|Rubrobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158188_k127_2845362_0	1122939.ATUD01000004_gene3721	6.698e-137	449.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CPQ3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_2845362_2	469383.Cwoe_0507	2.627e-62	222.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4CR1Z@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
SRR25158188_k127_2866070_8	479434.Sthe_0227	8.291e-27	110.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158188_k127_2866070_10	1385520.N802_13100	6.438e-10	64.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	1.13.11.24	ko:K07155	-	-	-	-	ko00000,ko01000	-	-	-	Cupin_2
SRR25158188_k127_2866070_1	351607.Acel_0025	3.854e-84	291.0	COG3391@1|root,COG3391@2|Bacteria,2I1IX@201174|Actinobacteria,4EVVE@85013|Frankiales	2|Bacteria	S	amine dehydrogenase activity	zinT	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	-
SRR25158188_k127_2866070_4	469383.Cwoe_0770	6.621e-49	182.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4CQ70@84995|Rubrobacteria	84995|Rubrobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158188_k127_2866070_9	1283299.AUKG01000002_gene4285	1.477e-15	83.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2866070_2	469383.Cwoe_4251	4.089e-72	258.0	COG0389@1|root,COG0389@2|Bacteria,2HPPZ@201174|Actinobacteria,4CR2N@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS
SRR25158188_k127_2866070_6	497321.C664_03987	4.298e-31	128.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,2KWX7@206389|Rhodocyclales	206389|Rhodocyclales	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRR25158188_k127_2866070_7	469383.Cwoe_4791	7.679e-28	122.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158188_k127_2866070_5	696281.Desru_0384	6.239e-32	133.0	COG2045@1|root,COG2045@2|Bacteria,1V56I@1239|Firmicutes,248U8@186801|Clostridia,261K1@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158188_k127_2866070_3	105425.BBPL01000012_gene1992	6.64e-57	213.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,2NHMX@228398|Streptacidiphilus	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158188_k127_2866070_0	370438.PTH_0903	2.556e-108	358.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,260B9@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158188_k127_2872924_0	266117.Rxyl_1621	2.299e-117	386.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CPGC@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158188_k127_2872924_4	1283299.AUKG01000003_gene592	4.804e-20	98.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQR5@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158188_k127_2872924_5	243230.DR_1082	1.363e-09	64.0	COG1544@1|root,COG1544@2|Bacteria,1WJUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158188_k127_2872924_3	266117.Rxyl_1623	2.474e-28	122.0	COG1040@1|root,COG1040@2|Bacteria,2HP3J@201174|Actinobacteria,4CQES@84995|Rubrobacteria	84995|Rubrobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158188_k127_2872924_2	1128421.JAGA01000002_gene1689	4.673e-86	293.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158188_k127_2872924_1	644966.Tmar_2110	1.759e-96	325.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158188_k127_287422_0	644966.Tmar_0825	2.132e-188	608.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WCD0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158188_k127_2876060_6	469383.Cwoe_1348	0.0002405	44.0	COG0255@1|root,COG0255@2|Bacteria,2HPC6@201174|Actinobacteria,4CQQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158188_k127_2876060_5	1122939.ATUD01000003_gene3575	1.124e-22	108.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CQJP@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158188_k127_2876060_1	469383.Cwoe_1350	6.734e-57	201.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158188_k127_2876060_3	644966.Tmar_2284	2.032e-27	123.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WCKT@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158188_k127_2876060_0	469383.Cwoe_1352	1.309e-68	244.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158188_k127_2876060_4	1033730.CAHG01000004_gene11	1.788e-23	106.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4DRSA@85009|Propionibacteriales	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158188_k127_2876060_2	471852.Tcur_4307	4.754e-48	175.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4EINA@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158188_k127_287885_6	883078.HMPREF9695_04072	7.806e-17	88.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,3JS33@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	MA20_18615	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158188_k127_287885_0	266117.Rxyl_2540	2.267e-191	618.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158188_k127_287885_4	1172188.KB911834_gene4138	1.536e-47	178.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158188_k127_287885_2	287986.DV20_38995	1.459e-55	205.0	COG0454@1|root,COG0456@2|Bacteria,2I94M@201174|Actinobacteria,4E38V@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158188_k127_287885_3	1118054.CAGW01000056_gene2111	5.546e-49	184.0	COG2030@1|root,COG2030@2|Bacteria,1V3VC@1239|Firmicutes,4HH24@91061|Bacilli	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158188_k127_287885_5	483219.LILAB_24950	5.345e-17	96.0	COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,4351D@68525|delta/epsilon subdivisions,2X948@28221|Deltaproteobacteria,2Z1TW@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_287885_1	1123504.JQKD01000004_gene5050	1.394e-87	306.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJB3@28216|Betaproteobacteria,4ABMH@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158188_k127_2880469_2	591167.Sfla_3899	7.118e-23	113.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158188_k127_2880469_3	1341151.ASZU01000004_gene299	1.289e-19	101.0	COG3584@1|root,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,27AX9@186824|Thermoactinomycetaceae	91061|Bacilli	S	G5	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
SRR25158188_k127_2880469_1	1262449.CP6013_3053	4.425e-29	132.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1TRU2@1239|Firmicutes,24K7H@186801|Clostridia	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158188_k127_2880469_0	369723.Strop_2411	3.019e-68	238.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4D99Q@85008|Micromonosporales	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158188_k127_2880826_6	1144307.PMI04_03277	2.436e-09	59.0	COG2146@1|root,COG2146@2|Bacteria,1NFMH@1224|Proteobacteria,2UIGJ@28211|Alphaproteobacteria,2K782@204457|Sphingomonadales	204457|Sphingomonadales	P	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158188_k127_2880826_3	458817.Shal_3766	4.615e-38	158.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RWPM@1236|Gammaproteobacteria,2QCJF@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
SRR25158188_k127_2880826_0	526225.Gobs_0843	2.769e-91	316.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158188_k127_2880826_1	1108045.GORHZ_036_00070	3.528e-88	294.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158188_k127_2880826_2	469383.Cwoe_3007	1.783e-63	222.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,4CRW2@84995|Rubrobacteria	84995|Rubrobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158188_k127_2880826_5	1463920.JOGB01000002_gene3224	3.484e-15	81.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158188_k127_2880826_4	479434.Sthe_2553	7.219e-37	148.0	COG4122@1|root,COG4122@2|Bacteria,2G97D@200795|Chloroflexi,27Y9I@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158188_k127_2888344_4	204669.Acid345_3018	0.000455	49.0	COG0745@1|root,COG3852@1|root,COG0745@2|Bacteria,COG3852@2|Bacteria,3Y993@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158188_k127_2888344_1	469383.Cwoe_2661	8.038e-83	303.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158188_k127_2888344_3	105422.BBPM01000070_gene370	1.672e-07	61.0	COG0454@1|root,COG0456@2|Bacteria,2GKQU@201174|Actinobacteria,2NF7A@228398|Streptacidiphilus	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158188_k127_2888344_0	526227.Mesil_1872	4.994e-239	762.0	COG1012@1|root,COG1012@2|Bacteria,1WJFH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158188_k127_2888344_2	926560.KE387023_gene1157	5.443e-15	78.0	COG2128@1|root,COG2128@2|Bacteria,1WMFR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158188_k127_2895899_1	405948.SACE_3384	6.681e-29	118.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4E3WR@85010|Pseudonocardiales	201174|Actinobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588,ko:K16028,ko:K21189	ko00360,ko00940,ko00941,ko00945,ko01051,ko01052,ko01059,ko01100,ko01110,map00360,map00940,map00941,map00945,map01051,map01052,map01059,map01100,map01110	M00039,M00350,M00828	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158188_k127_2895899_0	469383.Cwoe_3295	6.642e-179	569.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158188_k127_2895899_2	67352.JODS01000027_gene2389	3.24e-22	103.0	2E5JX@1|root,330B5@2|Bacteria,2GRDA@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
SRR25158188_k127_2909267_16	1457250.BBMO01000002_gene2052	1.493e-28	121.0	COG2335@1|root,arCOG03335@2157|Archaea,2Y78U@28890|Euryarchaeota,240QQ@183963|Halobacteria	183963|Halobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158188_k127_2909267_9	926690.KE386573_gene2861	2.174e-73	263.0	COG0702@1|root,arCOG03015@2157|Archaea,2XT7V@28890|Euryarchaeota,23T9H@183963|Halobacteria	183963|Halobacteria	M	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158188_k127_2909267_3	469383.Cwoe_2865	7.095e-117	387.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158188_k127_2909267_15	367299.JOEE01000007_gene36	1.19e-29	127.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,4FHME@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2909267_1	1157640.AQWO01000010_gene2933	2.425e-145	480.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158188_k127_2909267_13	404589.Anae109_0807	8.487e-37	153.0	COG4276@1|root,COG4276@2|Bacteria,1N6EC@1224|Proteobacteria,42U3N@68525|delta/epsilon subdivisions,2WQTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158188_k127_2909267_12	1336243.JAEA01000013_gene3244	3.45e-37	149.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,1JTC0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158188_k127_2909267_7	543632.JOJL01000035_gene5070	6.818e-78	270.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158188_k127_2909267_8	1307761.L21SP2_2808	2.346e-77	267.0	COG3752@1|root,COG3752@2|Bacteria,2J9PV@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158188_k127_2909267_11	928724.SacglDRAFT_03587	7.723e-48	176.0	COG3476@1|root,COG3476@2|Bacteria,2IQA5@201174|Actinobacteria,4E5Q1@85010|Pseudonocardiales	201174|Actinobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRR25158188_k127_2909267_4	497964.CfE428DRAFT_5336	1.263e-109	368.0	COG2230@1|root,COG2230@2|Bacteria,46TH2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158188_k127_2909267_14	1121468.AUBR01000014_gene2235	1.043e-29	134.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,42GFG@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158188_k127_2909267_5	1238190.AMQY01000010_gene2373	1.578e-89	321.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XHND@135619|Oceanospirillales	135619|Oceanospirillales	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158188_k127_2909267_10	1336235.JAEG01000009_gene2788	4.517e-48	188.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,4B8ZM@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
SRR25158188_k127_2909267_2	1121946.AUAX01000055_gene3685	3.827e-118	391.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria,4DBYA@85008|Micromonosporales	201174|Actinobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
SRR25158188_k127_2909267_6	469383.Cwoe_4990	1.145e-84	290.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158188_k127_2909267_17	1449044.JMLE01000032_gene4547	1.33e-12	76.0	COG2267@1|root,COG2267@2|Bacteria,2I3AW@201174|Actinobacteria,1WBBU@1268|Micrococcaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Peptidase_S9
SRR25158188_k127_2909267_0	251221.35214398	1.567e-158	514.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158188_k127_2928057_4	269800.Tfu_2143	2.851e-25	108.0	COG1208@1|root,COG1208@2|Bacteria,2GMX6@201174|Actinobacteria,4ENQR@85012|Streptosporangiales	201174|Actinobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR25158188_k127_2928057_1	1192034.CAP_6496	7.761e-35	142.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_2928057_3	525904.Tter_2661	2.686e-29	129.0	COG2365@1|root,COG2365@2|Bacteria,2NRBJ@2323|unclassified Bacteria	2|Bacteria	T	Tyrosine phosphatase family	iphP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158188_k127_2928057_2	469383.Cwoe_4611	8.739e-31	124.0	COG0789@1|root,COG0789@2|Bacteria,2HU1U@201174|Actinobacteria,4CTFE@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158188_k127_2928057_0	926569.ANT_16170	1.726e-159	508.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158188_k127_2930180_10	1380390.JIAT01000010_gene4148	7.071e-24	104.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CPNI@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158188_k127_2930180_7	1123321.KB905818_gene4875	1.328e-78	278.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158188_k127_2930180_9	292459.STH1211	3.152e-48	195.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158188_k127_2930180_11	521095.Apar_0488	1.632e-09	69.0	COG1589@1|root,COG1589@2|Bacteria,2HUMN@201174|Actinobacteria,4CV4T@84998|Coriobacteriia	84998|Coriobacteriia	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158188_k127_2930180_1	266117.Rxyl_1489	2.57e-142	460.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158188_k127_2930180_4	1380390.JIAT01000010_gene4156	1.955e-107	360.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CP79@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158188_k127_2930180_8	1380390.JIAT01000010_gene4157	5.18e-50	180.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158188_k127_2930180_2	1380390.JIAT01000010_gene4158	6.334e-138	457.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CP8Z@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158188_k127_2930180_0	264732.Moth_1942	1.839e-183	599.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,42FHX@68295|Thermoanaerobacterales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	Aminotran_5,GDC-P
SRR25158188_k127_2930180_3	1380390.JIAT01000010_gene4168	1.249e-136	444.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CQ1M@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158188_k127_2930180_6	309801.trd_1884	2.305e-82	287.0	COG2008@1|root,COG2008@2|Bacteria,2G7UV@200795|Chloroflexi,27XVE@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158188_k127_2930180_5	263358.VAB18032_28346	1.82e-89	310.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4DBNC@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_2944293_2	42256.RradSPS_1558	7.32e-82	276.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CPHA@84995|Rubrobacteria	84995|Rubrobacteria	D	ATPases associated with a variety of cellular activities	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158188_k127_2944293_5	469383.Cwoe_4586	2.432e-36	150.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CPSH@84995|Rubrobacteria	84995|Rubrobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158188_k127_2944293_1	526225.Gobs_2285	8.628e-104	358.0	COG1204@1|root,COG1204@2|Bacteria	2|Bacteria	L	response to ionizing radiation	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	DEAD,HIRAN,Helicase_C,SUV3_C
SRR25158188_k127_2944293_4	42256.RradSPS_0796	8.83e-43	160.0	COG2050@1|root,COG2050@2|Bacteria,2IR9T@201174|Actinobacteria,4CTI0@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158188_k127_2944293_7	1202532.FF52_05395	3.374e-16	85.0	2DMKA@1|root,32S5N@2|Bacteria,4NVRN@976|Bacteroidetes,1I76C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPW
SRR25158188_k127_2944293_3	351607.Acel_1728	1.707e-51	190.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4ESH9@85013|Frankiales	201174|Actinobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158188_k127_2944293_0	1380370.JIBA01000012_gene3905	7.641e-255	799.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2944293_8	187272.Mlg_0063	1.771e-15	90.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158188_k127_2944293_9	1282664.H354_06786	0.0001792	48.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158188_k127_2944293_6	1146883.BLASA_1767	2.105e-17	89.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2948659_3	1122939.ATUD01000017_gene4040	7.424e-64	227.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CPQ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158188_k127_2948659_2	1283299.AUKG01000002_gene3856	4.042e-72	265.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CPAU@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158188_k127_2948659_0	1380390.JIAT01000009_gene374	5.551e-184	591.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
SRR25158188_k127_2948659_5	1120934.KB894446_gene3466	2.857e-58	212.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DZNW@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2948659_6	391037.Sare_4989	8.709e-58	219.0	COG0642@1|root,COG2205@2|Bacteria,2I53J@201174|Actinobacteria,4DMQB@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158188_k127_2948659_4	644966.Tmar_0092	3.96e-62	239.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
SRR25158188_k127_2948659_7	525909.Afer_1810	7.462e-27	121.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158188_k127_2948659_1	1380390.JIAT01000009_gene371	4.9e-83	284.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158188_k127_2957008_9	596154.Alide2_1834	3.812e-40	156.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJJD@28216|Betaproteobacteria,4ABX4@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158188_k127_2957008_4	479434.Sthe_0007	2.865e-92	314.0	COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi,27YV0@189775|Thermomicrobia	189775|Thermomicrobia	E	HMGL-like	-	-	4.1.3.46	ko:K18314	-	-	R10674	RC00502,RC01205	ko00000,ko01000	-	-	-	HMGL-like
SRR25158188_k127_2957008_1	1502851.FG93_05300	1.653e-144	484.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2VFAY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158188_k127_2957008_5	1380347.JNII01000008_gene4082	4.327e-81	278.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4ESYW@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158188_k127_2957008_3	1156844.KB891807_gene1628	4.895e-102	340.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158188_k127_2957008_6	644283.Micau_0964	1.921e-80	282.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4D9ZP@85008|Micromonosporales	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158188_k127_2957008_2	1380390.JIAT01000010_gene4484	7.448e-123	406.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158188_k127_2957008_0	351607.Acel_1287	2.544e-162	524.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4ERWH@85013|Frankiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158188_k127_2957008_8	469383.Cwoe_2602	5.233e-43	163.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4CTFY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158188_k127_2957008_7	1380390.JIAT01000010_gene4613	1.459e-62	223.0	COG0491@1|root,COG0491@2|Bacteria,2HNRR@201174|Actinobacteria,4CPZ8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_2960174_3	926564.KI911760_gene4939	4.762e-35	138.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_2960174_1	1386089.N865_01325	5.355e-101	351.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4FEN1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158188_k127_2960174_0	469383.Cwoe_0746	1.174e-125	410.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CPUE@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158188_k127_2960174_2	247490.KSU1_C1363	5.31e-94	323.0	COG1071@1|root,COG1071@2|Bacteria,2IXGM@203682|Planctomycetes	203682|Planctomycetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158188_k127_2962298_2	1380390.JIAT01000009_gene1442	2.417e-62	220.0	COG0559@1|root,COG0559@2|Bacteria,2GJM0@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158188_k127_2962298_1	1380390.JIAT01000009_gene1443	6.03e-103	352.0	COG0683@1|root,COG0683@2|Bacteria,2GJ2V@201174|Actinobacteria,4CTNJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158188_k127_2962298_0	298655.KI912266_gene2926	3.784e-172	553.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.67	ko:K21802	ko00627,ko01120,map00627,map01120	-	R05699	RC00075	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158188_k127_2962996_4	44060.JODL01000009_gene1828	2.769e-56	206.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158188_k127_2962996_1	469383.Cwoe_3731	1.153e-128	438.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CPBT@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158188_k127_2962996_7	74547.PMT_1998	7.104e-22	109.0	COG0204@1|root,COG0204@2|Bacteria,1G173@1117|Cyanobacteria,1MKSH@1212|Prochloraceae	1117|Cyanobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158188_k127_2962996_6	469378.Ccur_06850	2.095e-52	196.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CV84@84998|Coriobacteriia	84998|Coriobacteriia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158188_k127_2962996_3	1234364.AMSF01000039_gene8	1.658e-111	378.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1X36A@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158188_k127_2962996_0	1283299.AUKG01000002_gene4648	5.373e-129	420.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria,4CPFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158188_k127_2962996_2	1120971.AUCA01000021_gene1029	4.347e-114	377.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,2781H@186823|Alicyclobacillaceae	91061|Bacilli	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158188_k127_2962996_5	485913.Krac_11842	1.927e-52	198.0	28JU5@1|root,2Z9J8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158188_k127_2965838_5	469383.Cwoe_3688	1.021e-65	230.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158188_k127_2965838_6	1192034.CAP_4742	1.212e-60	223.0	COG4403@1|root,COG4403@2|Bacteria,1PR3F@1224|Proteobacteria	1224|Proteobacteria	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158188_k127_2965838_2	469383.Cwoe_5326	9.316e-100	344.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria,4CPBH@84995|Rubrobacteria	84995|Rubrobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158188_k127_2965838_4	469383.Cwoe_5326	9.672e-89	327.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria,4CPBH@84995|Rubrobacteria	84995|Rubrobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158188_k127_2965838_3	264732.Moth_0962	1.886e-89	304.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42ENW@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158188_k127_2965838_0	1144312.PMI09_04985	1.17e-200	661.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,SAM_1,SAM_2,TPR_12,TPR_4
SRR25158188_k127_2965838_1	868595.Desca_1100	3.494e-153	496.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2610F@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158188_k127_2969564_0	235985.BBPN01000057_gene7794	2.217e-130	425.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,2NFNP@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_2969564_2	1211815.CBYP010000014_gene3514	7.908e-74	265.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158188_k127_2969564_4	316278.SynRCC307_2405	5.096e-06	55.0	COG4803@1|root,COG4803@2|Bacteria,1G531@1117|Cyanobacteria,1GZS1@1129|Synechococcus	1117|Cyanobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158188_k127_2969564_3	1283299.AUKG01000001_gene2476	4.949e-31	127.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2969564_1	1380390.JIAT01000011_gene2299	1.485e-85	300.0	COG3025@1|root,COG3025@2|Bacteria,2IN8R@201174|Actinobacteria,4CSIW@84995|Rubrobacteria	84995|Rubrobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2969564_5	1380390.JIAT01000011_gene2288	3.223e-05	51.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Ppx-GppA
SRR25158188_k127_2980458_3	1283299.AUKG01000001_gene3152	1.085e-10	74.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4CQGR@84995|Rubrobacteria	84995|Rubrobacteria	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158188_k127_2980458_1	1382306.JNIM01000001_gene1035	8.217e-108	359.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158188_k127_2980458_2	1122939.ATUD01000002_gene1254	5.292e-19	93.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158188_k127_2980458_0	485913.Krac_6683	1.751e-152	494.0	COG0476@1|root,COG0476@2|Bacteria,2G5TN@200795|Chloroflexi	200795|Chloroflexi	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158188_k127_2982806_7	266117.Rxyl_0187	2.28e-16	85.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_2982806_2	909663.KI867150_gene68	2.157e-106	365.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MRH3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
SRR25158188_k127_2982806_4	929712.KI912613_gene1364	1.5e-84	302.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
SRR25158188_k127_2982806_6	1386089.N865_21015	5.653e-25	116.0	2D6K8@1|root,32TMG@2|Bacteria,2GR9V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_2982806_0	1380390.JIAT01000010_gene4890	5.902e-156	542.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158188_k127_2982806_8	887929.HMP0721_0235	3.091e-12	73.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,25WYU@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158188_k127_2982806_1	1382304.JNIL01000001_gene1065	7.771e-117	386.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,27827@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158188_k127_2982806_3	266117.Rxyl_1329	6.823e-94	317.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158188_k127_2982806_5	1408254.T458_14325	7.774e-47	181.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,4HC8D@91061|Bacilli,26QUR@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158188_k127_2994713_5	1392838.AWNM01000047_gene2045	1.038e-20	104.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,3T3NG@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158188_k127_2994713_1	469383.Cwoe_2668	2.548e-104	352.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CPMW@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158188_k127_2994713_4	469383.Cwoe_2665	6.016e-26	118.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CQPP@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158188_k127_2994713_6	469383.Cwoe_2664	1.119e-18	97.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CQJ4@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158188_k127_2994713_0	469383.Cwoe_2663	5.185e-168	561.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CPSJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158188_k127_2994713_2	1380390.JIAT01000002_gene5999	4.104e-91	315.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158188_k127_2994713_3	469383.Cwoe_2661	9.131e-75	267.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158188_k127_299710_2	1283299.AUKG01000002_gene4032	4.057e-65	234.0	COG0393@1|root,COG0393@2|Bacteria,2I9NA@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158188_k127_299710_0	1283299.AUKG01000002_gene4034	1.016e-144	463.0	COG0393@1|root,COG0393@2|Bacteria,2I9NA@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158188_k127_299710_1	1123267.JONN01000001_gene638	3.259e-129	421.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2K1KY@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158188_k127_299710_4	463191.SSEG_01935	3.833e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,2IKKR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_299710_3	929712.KI912613_gene831	4.87e-42	163.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria,4CQPT@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
SRR25158188_k127_3015796_4	1380390.JIAT01000010_gene3918	1.271e-71	257.0	COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158188_k127_3015796_10	765420.OSCT_2907	9.398e-07	60.0	COG2905@1|root,COG2905@2|Bacteria,2G9RT@200795|Chloroflexi,375Z7@32061|Chloroflexia	32061|Chloroflexia	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158188_k127_3015796_3	1179773.BN6_38060	2.857e-89	306.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4DYVV@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158188_k127_3015796_0	1380390.JIAT01000010_gene3879	0.0	1245.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CSGY@84995|Rubrobacteria	84995|Rubrobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158188_k127_3015796_6	1380390.JIAT01000010_gene3926	2.802e-48	183.0	2AWR3@1|root,31NN1@2|Bacteria,2HR71@201174|Actinobacteria,4CT2W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3015796_5	1283283.ATXA01000020_gene1321	2.644e-59	222.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4EX5F@85013|Frankiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_3015796_2	1122939.ATUD01000001_gene812	2.23e-109	373.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4CU6T@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158188_k127_3015796_9	1078020.KEK_23186	1.457e-11	71.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,2343K@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158188_k127_3015796_1	867903.ThesuDRAFT_00352	2.126e-233	763.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
SRR25158188_k127_3015796_8	331869.BAL199_10145	5.482e-21	97.0	COG1977@1|root,COG1977@2|Bacteria,1N0ZW@1224|Proteobacteria,2UCKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158188_k127_3015796_7	1121033.AUCF01000008_gene5705	1.982e-42	158.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2JRNW@204441|Rhodospirillales	204441|Rhodospirillales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3021170_1	1394178.AWOO02000037_gene9175	2.235e-12	73.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria,4EQV1@85012|Streptosporangiales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158188_k127_3021170_0	266117.Rxyl_0884	1.275e-13	76.0	COG0662@1|root,COG0662@2|Bacteria,2I5KR@201174|Actinobacteria,4CTK8@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_3036077_3	186497.PF0547	1.307e-170	546.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158188_k127_3036077_13	326427.Cagg_2230	2.553e-11	72.0	COG2905@1|root,COG2905@2|Bacteria,2G9RT@200795|Chloroflexi,375Z7@32061|Chloroflexia	32061|Chloroflexia	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158188_k127_3036077_1	266117.Rxyl_1110	4.878e-182	580.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158188_k127_3036077_5	525904.Tter_0805	9.281e-154	496.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158188_k127_3036077_2	706587.Desti_4338	1.207e-180	571.0	COG2502@1|root,COG2502@2|Bacteria,1MVWF@1224|Proteobacteria	1224|Proteobacteria	E	aspartate--ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA,tRNA-synt_2
SRR25158188_k127_3036077_4	106370.Francci3_4500	9.907e-166	529.0	COG0247@1|root,COG0247@2|Bacteria,2I3IR@201174|Actinobacteria,4EUJ2@85013|Frankiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRR25158188_k127_3036077_9	351607.Acel_1016	5.672e-58	207.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria,4EVPM@85013|Frankiales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158188_k127_3036077_8	35754.JNYJ01000042_gene1375	1.479e-80	277.0	COG0543@1|root,COG0543@2|Bacteria,2HXFY@201174|Actinobacteria,4DCVX@85008|Micromonosporales	201174|Actinobacteria	CH	Oxidoreductase NAD-binding domain	asrB	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158188_k127_3036077_6	222534.KB893729_gene5665	2.894e-117	390.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria,4EU21@85013|Frankiales	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
SRR25158188_k127_3036077_0	351607.Acel_1019	1.673e-195	618.0	COG3259@1|root,COG3259@2|Bacteria,2GQ33@201174|Actinobacteria,4EUTB@85013|Frankiales	201174|Actinobacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SRR25158188_k127_3036077_10	518766.Rmar_2591	4.893e-32	133.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hoxW	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158188_k127_3036077_14	469371.Tbis_3231	5.1e-05	49.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,4E764@85010|Pseudonocardiales	201174|Actinobacteria	O	HupF/HypC family	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158188_k127_3036077_7	351607.Acel_1022	3.414e-96	330.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_3036077_11	1312959.KI914686_gene2092	4.721e-25	111.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3043793_1	1380390.JIAT01000010_gene4831	9.907e-93	315.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158188_k127_3043793_3	1380390.JIAT01000010_gene4830	4.572e-51	191.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158188_k127_3043793_0	67257.JODR01000014_gene5801	9.487e-119	389.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158188_k127_3043793_2	469383.Cwoe_3264	8.691e-74	256.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,4CPPK@84995|Rubrobacteria	84995|Rubrobacteria	E	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158188_k127_3043793_4	66377.JOBH01000006_gene197	2.14e-43	173.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158188_k127_3044066_0	1123377.AUIV01000012_gene702	1.587e-145	477.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales	135614|Xanthomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158188_k127_3044066_1	469383.Cwoe_2903	4.63e-114	379.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158188_k127_3044066_2	42256.RradSPS_0987	8.814e-27	116.0	COG0297@1|root,COG0297@2|Bacteria,2I4BF@201174|Actinobacteria,4CU41@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158188_k127_3053575_7	266117.Rxyl_2723	2.366e-74	261.0	COG0243@1|root,COG0243@2|Bacteria,2GJ7X@201174|Actinobacteria,4CQ4D@84995|Rubrobacteria	84995|Rubrobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4
SRR25158188_k127_3053575_0	266117.Rxyl_2724	0.0	1217.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GJCK@201174|Actinobacteria,4CPFZ@84995|Rubrobacteria	84995|Rubrobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158188_k127_3053575_4	1394178.AWOO02000074_gene2229	4.511e-122	420.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4EHKG@85012|Streptosporangiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4
SRR25158188_k127_3053575_6	266117.Rxyl_2726	9.871e-81	295.0	COG3301@1|root,COG3301@2|Bacteria,2GJ4S@201174|Actinobacteria,4CQ3J@84995|Rubrobacteria	84995|Rubrobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158188_k127_3053575_5	479434.Sthe_0004	1.72e-116	387.0	COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi,27XTW@189775|Thermomicrobia	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158188_k127_3053575_1	351607.Acel_1394	0.0	1173.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158188_k127_3053575_3	1380390.JIAT01000010_gene3977	2.275e-159	530.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b	qcrB	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158188_k127_3053575_8	1380390.JIAT01000010_gene3976	1.161e-53	202.0	COG0723@1|root,COG0723@2|Bacteria,2HGHS@201174|Actinobacteria,4CTW3@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158188_k127_3053575_9	1380390.JIAT01000010_gene3975	1.488e-50	194.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158188_k127_3053575_10	1165094.RINTHH_7260	1.842e-14	88.0	COG1845@1|root,COG1845@2|Bacteria,1G02A@1117|Cyanobacteria,1HK9A@1161|Nostocales	1117|Cyanobacteria	C	PFAM cytochrome c oxidase, subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158188_k127_3053575_2	1038869.AXAN01000042_gene2834	4.21e-205	656.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VM0G@28216|Betaproteobacteria,1K22G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298,ko:K15408	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1,COX3
SRR25158188_k127_3053951_1	1429046.RR21198_1984	7.204e-128	420.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4G023@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158188_k127_3053951_0	1380390.JIAT01000011_gene2544	2.29e-148	480.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4CU64@84995|Rubrobacteria	84995|Rubrobacteria	I	Phospholipase D Active site motif	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
SRR25158188_k127_3065371_3	40571.JOEA01000018_gene7984	3.099e-87	298.0	COG1680@1|root,COG1680@2|Bacteria,2I2WV@201174|Actinobacteria,4E1FY@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_3065371_5	266940.Krad_2211	1.784e-60	215.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158188_k127_3065371_1	235985.BBPN01000048_gene8244	1.16e-137	452.0	COG1680@1|root,COG1680@2|Bacteria,2I2WV@201174|Actinobacteria,2NI41@228398|Streptacidiphilus	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158188_k127_3065371_2	390989.JOEG01000018_gene3579	9.118e-107	356.0	COG4608@1|root,COG4608@2|Bacteria,2HMST@201174|Actinobacteria,4DIG2@85008|Micromonosporales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_3065371_0	479432.Sros_5709	5.443e-203	659.0	COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,2GIXV@201174|Actinobacteria,4EFFP@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
SRR25158188_k127_3065371_4	330084.JNYZ01000005_gene823	5.046e-74	254.0	COG0601@1|root,COG0601@2|Bacteria,2GJFF@201174|Actinobacteria,4E1PK@85010|Pseudonocardiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_3119550_0	28444.JODQ01000018_gene7270	3.114e-281	875.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4EFQQ@85012|Streptosporangiales	201174|Actinobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158188_k127_3119550_3	1283299.AUKG01000001_gene2880	2.479e-45	169.0	2E2SC@1|root,32XUP@2|Bacteria,2IQXZ@201174|Actinobacteria	201174|Actinobacteria	S	Allene oxide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Allene_ox_cyc
SRR25158188_k127_3119550_1	710111.FraQA3DRAFT_3907	2.431e-149	480.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4ERDE@85013|Frankiales	201174|Actinobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158188_k127_3119550_2	1380346.JNIH01000010_gene2900	1.103e-71	258.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158188_k127_313132_5	208444.JNYY01000001_gene4738	3.308e-42	160.0	COG0601@1|root,COG0601@2|Bacteria,2GJFF@201174|Actinobacteria,4E1PK@85010|Pseudonocardiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_313132_2	1306174.JODP01000007_gene2520	2.396e-115	389.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_313132_0	479435.Kfla_4916	2.699e-212	670.0	COG1506@1|root,COG1680@1|root,COG1506@2|Bacteria,COG1680@2|Bacteria,2GMMM@201174|Actinobacteria,4DPKW@85009|Propionibacteriales	201174|Actinobacteria	EU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,PD40,Peptidase_S9
SRR25158188_k127_313132_3	479433.Caci_4254	3.266e-100	344.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158188_k127_313132_4	591158.SSMG_06587	1.238e-65	240.0	COG3375@1|root,COG3375@2|Bacteria,2I8MV@201174|Actinobacteria	201174|Actinobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_313132_1	479433.Caci_4256	1.035e-161	517.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158188_k127_3136587_4	1298863.AUEP01000019_gene3529	2.347e-18	91.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DT5X@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_3136587_1	266117.Rxyl_1532	1.026e-48	177.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CQFJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158188_k127_3136587_2	469383.Cwoe_2655	2.444e-41	159.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158188_k127_3136587_0	469383.Cwoe_2653	1.397e-67	244.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158188_k127_3136587_3	2074.JNYD01000006_gene1651	2.347e-21	100.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4DXKT@85010|Pseudonocardiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158188_k127_3143533_6	383372.Rcas_0555	3.58e-06	59.0	COG2152@1|root,COG2152@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158188_k127_3143533_2	1323361.JPOC01000017_gene2072	2.209e-39	156.0	COG0726@1|root,COG0726@2|Bacteria,2HFSE@201174|Actinobacteria,4G6KU@85025|Nocardiaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158188_k127_3143533_7	2002.JOEQ01000037_gene4264	9.603e-06	54.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158188_k127_3143533_8	1385935.N836_13325	0.0002285	53.0	COG3307@1|root,COG3307@2|Bacteria,1G15X@1117|Cyanobacteria,1H7X0@1150|Oscillatoriales	1117|Cyanobacteria	M	O-antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158188_k127_3143533_4	28072.Nos7524_0297	1.083e-34	149.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_3143533_5	1337093.MBE-LCI_3111	1.849e-29	132.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2UFEC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_3143533_3	469383.Cwoe_5300	1.18e-38	156.0	COG5017@1|root,COG5017@2|Bacteria	2|Bacteria	T	Glycosyltransferase family 28 C-terminal domain	pssE	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
SRR25158188_k127_3143533_1	525904.Tter_2795	5.773e-47	181.0	COG0438@1|root,COG0438@2|Bacteria,2NPSJ@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158188_k127_3143533_0	690850.Desaf_0734	3.82e-58	216.0	COG0438@1|root,COG0438@2|Bacteria,1PERD@1224|Proteobacteria,42VK8@68525|delta/epsilon subdivisions,2WSBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_3151443_1	1415166.NONO_c66400	1.93e-48	179.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4FWYC@85025|Nocardiaceae	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158188_k127_3151443_0	1048339.KB913029_gene4146	3.399e-138	465.0	COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria,4EURS@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158188_k127_315880_10	469383.Cwoe_0731	7.553e-49	190.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria	201174|Actinobacteria	CP	ABC-type Na efflux pump, permease	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158188_k127_315880_5	469383.Cwoe_0732	1.89e-84	295.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158188_k127_315880_15	479431.Namu_0122	1.595e-11	72.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4EUXE@85013|Frankiales	201174|Actinobacteria	E	Amino acid permease	gabP	-	-	ko:K03293,ko:K11735	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.4,2.A.3.1.5	-	iNJ661.Rv0522	AA_permease
SRR25158188_k127_315880_16	356851.JOAN01000008_gene2956	3.78e-10	71.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4DDIK@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158188_k127_315880_13	266117.Rxyl_1008	2.171e-28	128.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_315880_4	405948.SACE_3653	5.097e-90	308.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DZ7C@85010|Pseudonocardiales	201174|Actinobacteria	P	membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158188_k127_315880_6	1120985.AUMI01000004_gene1325	1.617e-73	258.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_315880_11	485913.Krac_1851	2.901e-45	188.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158188_k127_315880_12	1297742.A176_07382	4.116e-33	143.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158188_k127_315880_2	882083.SacmaDRAFT_3191	8.523e-127	421.0	2DBMB@1|root,2Z9Y8@2|Bacteria,2I4DG@201174|Actinobacteria,4EDSK@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158188_k127_315880_3	350058.Mvan_1084	1.888e-119	400.0	COG2267@1|root,COG2267@2|Bacteria,2I9JC@201174|Actinobacteria	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158188_k127_315880_14	1056816.JAFQ01000004_gene5382	1.366e-20	106.0	COG3467@1|root,COG3467@2|Bacteria,2I2V6@201174|Actinobacteria,4G2S1@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158188_k127_315880_9	479431.Namu_0372	3.168e-57	206.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158188_k127_315880_17	1172185.KB911523_gene3481	5.552e-10	71.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4FWS6@85025|Nocardiaceae	201174|Actinobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158188_k127_315880_1	1122132.AQYH01000020_gene46	4.823e-162	544.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR56@28211|Alphaproteobacteria,4B7DZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,HlyD_D23,Hydrolase
SRR25158188_k127_315880_0	469383.Cwoe_1723	6.601e-212	686.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CRWU@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPase (P-type)	-	-	3.6.3.8	ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158188_k127_315880_8	43354.JOIJ01000005_gene2243	8.204e-61	232.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SLT
SRR25158188_k127_315880_7	929712.KI912613_gene1267	6.469e-63	227.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CQD7@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158188_k127_3160668_0	443255.SCLAV_3445	6.613e-75	263.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158188_k127_3160668_1	1121468.AUBR01000010_gene2431	4.882e-35	141.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158188_k127_3162294_4	1133849.O3I_034795	3.073e-38	152.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria,4G31F@85025|Nocardiaceae	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158188_k127_3162294_0	1121468.AUBR01000029_gene1549	5.243e-174	565.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42F33@68295|Thermoanaerobacterales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158188_k127_3162294_2	1137271.AZUM01000001_gene1612	3.536e-72	263.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4E1CY@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158188_k127_3162294_1	543632.JOJL01000010_gene7177	7.227e-108	370.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158188_k127_3162294_3	1120948.KB903218_gene1920	6.589e-60	223.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DZK6@85010|Pseudonocardiales	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158188_k127_3162294_5	66377.JOBH01000006_gene197	3.137e-23	101.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158188_k127_3178356_3	469383.Cwoe_4686	2.759e-77	271.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CQ5A@84995|Rubrobacteria	84995|Rubrobacteria	H	molybdopterin binding domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158188_k127_3178356_5	42256.RradSPS_0023	2.568e-61	227.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158188_k127_3178356_1	1123511.KB905874_gene1	2.301e-104	370.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158188_k127_3178356_10	1283299.AUKG01000001_gene1834	4.509e-25	114.0	COG0668@1|root,COG0668@2|Bacteria,2GJ51@201174|Actinobacteria,4CRRK@84995|Rubrobacteria	84995|Rubrobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158188_k127_3178356_12	1158345.JNLL01000001_gene18	2.411e-21	100.0	COG4911@1|root,COG4911@2|Bacteria,2G57N@200783|Aquificae	200783|Aquificae	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158188_k127_3178356_16	485913.Krac_10615	2.999e-07	60.0	COG1266@1|root,COG1266@2|Bacteria,2G9H5@200795|Chloroflexi	200795|Chloroflexi	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158188_k127_3178356_6	469383.Cwoe_5941	6.478e-61	220.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158188_k127_3178356_4	469383.Cwoe_5942	1.297e-63	231.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CPD6@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158188_k127_3178356_2	1283299.AUKG01000001_gene1771	3.186e-81	283.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CQ24@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158188_k127_3178356_9	429009.Adeg_2147	5.97e-27	118.0	COG0357@1|root,COG0357@2|Bacteria,1W6WG@1239|Firmicutes,25MN8@186801|Clostridia,42IXD@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158188_k127_3178356_8	1408423.JHYA01000004_gene2228	1.145e-33	140.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4H41I@909932|Negativicutes	909932|Negativicutes	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158188_k127_3178356_7	1380390.JIAT01000009_gene1795	6.586e-50	189.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CPXT@84995|Rubrobacteria	84995|Rubrobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158188_k127_3178356_13	1283299.AUKG01000001_gene1765	4.227e-20	97.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4CQSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158188_k127_3178356_11	469383.Cwoe_5949	6.367e-23	102.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4CQCA@84995|Rubrobacteria	84995|Rubrobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158188_k127_3178356_14	1313172.YM304_42910	5.97e-10	64.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4CP4C@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158188_k127_3178356_0	1160707.AJIK01000044_gene1703	8.261e-146	476.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,26E4R@186818|Planococcaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158188_k127_3178356_15	266117.Rxyl_0002	1.658e-08	59.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158188_k127_3185273_5	269799.Gmet_0931	7.914e-21	103.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
SRR25158188_k127_3185273_4	266117.Rxyl_0283	1.883e-95	323.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158188_k127_3185273_2	543632.JOJL01000004_gene4329	8.506e-128	421.0	COG1940@1|root,COG1940@2|Bacteria,2GJ3W@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158188_k127_3185273_0	105425.BBPL01000003_gene6808	1.725e-182	589.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,2NFI0@228398|Streptacidiphilus	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_3185273_1	1380347.JNII01000005_gene3565	3.691e-130	423.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158188_k127_3185273_3	1463820.JOGW01000008_gene1444	1.841e-103	364.0	COG1173@1|root,COG1173@2|Bacteria,2IBS7@201174|Actinobacteria	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158188_k127_319074_6	1157635.KB892004_gene4558	3.46e-09	61.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158188_k127_319074_3	387631.Asulf_00881	2.571e-36	149.0	COG1014@1|root,COG1144@1|root,arCOG01603@2157|Archaea,arCOG01605@2157|Archaea,2XYDT@28890|Euryarchaeota	28890|Euryarchaeota	C	TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit	porC-2	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SRR25158188_k127_319074_2	1121468.AUBR01000064_gene940	3.203e-72	265.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,42EUF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158188_k127_319074_1	933262.AXAM01000011_gene1757	3.651e-74	265.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MJ2R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158188_k127_319074_5	330214.NIDE3895	1.944e-13	81.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	ymaD	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158188_k127_319074_0	300852.55772146	7.077e-131	426.0	COG0235@1|root,COG0235@2|Bacteria,1WID4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158188_k127_319074_4	645991.Sgly_1757	2.484e-20	107.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,261N2@186807|Peptococcaceae	186801|Clostridia	M	PFAM Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158188_k127_3192043_2	1283299.AUKG01000002_gene3680	3.428e-66	242.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4CPTF@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158188_k127_3192043_0	1380390.JIAT01000009_gene545	0.0	1029.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158188_k127_3192043_1	1380390.JIAT01000009_gene546	4.18e-87	291.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4CPJA@84995|Rubrobacteria	84995|Rubrobacteria	G	protein, probably involved in trehalose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158188_k127_3201328_6	1380390.JIAT01000001_gene5078	3.597e-09	65.0	COG1404@1|root,COG1404@2|Bacteria,2HFRU@201174|Actinobacteria,4CRQD@84995|Rubrobacteria	84995|Rubrobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158188_k127_3201328_3	1329516.JPST01000014_gene491	6.096e-62	220.0	COG1207@1|root,COG1207@2|Bacteria,1UIKN@1239|Firmicutes,4HC88@91061|Bacilli,27B78@186824|Thermoactinomycetaceae	91061|Bacilli	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158188_k127_3201328_2	1379698.RBG1_1C00001G1537	3.509e-78	286.0	COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,Hexapep,Hexapep_2
SRR25158188_k127_3201328_0	926569.ANT_31630	2.438e-142	466.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158188_k127_3201328_1	469383.Cwoe_5917	2.021e-101	341.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CTCM@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158188_k127_3201328_5	596154.Alide2_1292	2.929e-27	126.0	COG0438@1|root,COG0438@2|Bacteria,1R4V8@1224|Proteobacteria,2VNZK@28216|Betaproteobacteria,4ADAH@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
SRR25158188_k127_3201328_4	1123242.JH636434_gene4961	8.971e-28	129.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
SRR25158188_k127_3236469_8	1444309.JAQG01000025_gene3710	2.67e-29	121.0	COG2041@1|root,COG2041@2|Bacteria,1UMMR@1239|Firmicutes,4HF9N@91061|Bacilli,275MG@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158188_k127_3236469_9	1122939.ATUD01000012_gene3145	2.728e-28	126.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158188_k127_3236469_10	1380390.JIAT01000015_gene5664	5.848e-16	82.0	2AX10@1|root,31NZ1@2|Bacteria,2HRFE@201174|Actinobacteria,4CTE5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3236469_5	42256.RradSPS_1881	9.093e-66	235.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158188_k127_3236469_4	379066.GAU_3533	1.388e-103	351.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158188_k127_3236469_3	644966.Tmar_2129	1.436e-162	520.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158188_k127_3236469_1	1283299.AUKG01000001_gene3268	2.291e-193	614.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4CQX3@84995|Rubrobacteria	84995|Rubrobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR25158188_k127_3236469_7	1396418.BATQ01000117_gene4545	1.483e-29	128.0	COG0346@1|root,COG0346@2|Bacteria,46VWA@74201|Verrucomicrobia,2IVZP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_3236469_11	316067.Geob_0678	4.737e-15	81.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,42U5S@68525|delta/epsilon subdivisions,2WQRJ@28221|Deltaproteobacteria,43SQN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158188_k127_3236469_6	351607.Acel_0290	8.154e-41	157.0	COG1309@1|root,COG1309@2|Bacteria,2GYI1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158188_k127_3236469_2	1380390.JIAT01000009_gene817	1.758e-173	564.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRWB@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_3236469_0	1121946.AUAX01000040_gene5631	7.442e-209	666.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4D93Z@85008|Micromonosporales	201174|Actinobacteria	J	Elongation factor G, domain IV	tetP	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158188_k127_3240406_8	42256.RradSPS_0789	3.412e-10	61.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CQJ6@84995|Rubrobacteria	84995|Rubrobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158188_k127_3240406_6	1380390.JIAT01000009_gene727	5.203e-42	171.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CQ60@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158188_k127_3240406_4	463191.SSEG_07172	9.216e-75	267.0	COG0334@1|root,COG0334@2|Bacteria,2IHIC@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158188_k127_3240406_9	290340.AAur_3232	4.407e-05	50.0	COG4767@1|root,COG4767@2|Bacteria	2|Bacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158188_k127_3240406_2	1232436.CAPF01000089_gene285	9.308e-84	293.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CUC8@84998|Coriobacteriia	84998|Coriobacteriia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158188_k127_3240406_1	1121946.AUAX01000005_gene5339	1.427e-119	398.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4D8CT@85008|Micromonosporales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158188_k127_3240406_7	243231.GSU0660	8.705e-30	132.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158188_k127_3240406_5	469383.Cwoe_5257	2.222e-56	213.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158188_k127_3240406_3	469383.Cwoe_5258	6.065e-76	267.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CPR6@84995|Rubrobacteria	84995|Rubrobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158188_k127_3240406_0	1521187.JPIM01000016_gene3690	7.951e-220	689.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,37527@32061|Chloroflexia	32061|Chloroflexia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158188_k127_3249769_0	469383.Cwoe_1144	3.265e-207	664.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CSJJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158188_k127_3249769_2	1123023.JIAI01000011_gene8873	1.399e-29	130.0	COG2334@1|root,COG2334@2|Bacteria,2IGYG@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158188_k127_3249769_3	404589.Anae109_3016	6.129e-28	128.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158188_k127_3249769_1	1122609.AUGT01000029_gene2640	8.325e-125	401.0	COG0702@1|root,COG0702@2|Bacteria,2HVU1@201174|Actinobacteria,4DTYQ@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158188_k127_3249769_4	1140.Synpcc7942_0213	0.0001335	49.0	2DQ7P@1|root,33553@2|Bacteria,1GH5S@1117|Cyanobacteria,1H3C8@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3276378_6	1380390.JIAT01000014_gene6270	4.808e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_3276378_11	1321786.HMPREF1992_00078	1.868e-05	55.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4H52Z@909932|Negativicutes	909932|Negativicutes	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
SRR25158188_k127_3276378_8	693977.Deipr_0211	1.133e-47	180.0	COG0566@1|root,COG0566@2|Bacteria,1WIZZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158188_k127_3276378_0	1283299.AUKG01000001_gene3020	7.374e-119	395.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CP99@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158188_k127_3276378_5	266117.Rxyl_2174	1.541e-54	204.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158188_k127_3276378_9	593117.TGAM_0991	2.95e-37	158.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,242M3@183968|Thermococci	183968|Thermococci	S	gtp1 obg	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
SRR25158188_k127_3276378_1	1380390.JIAT01000009_gene488	5.357e-111	370.0	COG0300@1|root,COG0300@2|Bacteria,2GJ1R@201174|Actinobacteria,4CRHH@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158188_k127_3276378_2	469383.Cwoe_3526	3.592e-82	291.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158188_k127_3276378_3	1283299.AUKG01000004_gene1147	1.49e-73	254.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CQT2@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158188_k127_3276378_4	42256.RradSPS_2163	4.889e-55	199.0	COG0454@1|root,COG0456@2|Bacteria,2GK76@201174|Actinobacteria	201174|Actinobacteria	K	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158188_k127_3276378_7	264732.Moth_2486	4.168e-50	182.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,42FTZ@68295|Thermoanaerobacterales	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158188_k127_3276378_10	1172188.KB911830_gene3834	7.507e-14	72.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4FGMU@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158188_k127_3290549_3	469383.Cwoe_4380	1.599e-38	149.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CPJW@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158188_k127_3290549_2	1177594.MIC448_930014	3.87e-40	168.0	COG0683@1|root,COG0683@2|Bacteria,2I9D3@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158188_k127_3290549_5	1394178.AWOO02000015_gene7108	7.466e-35	145.0	COG1082@1|root,COG1082@2|Bacteria,2IEA7@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158188_k127_3290549_0	469383.Cwoe_2023	8.473e-43	165.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158188_k127_3290549_1	479434.Sthe_2618	3.704e-40	166.0	COG1834@1|root,COG1834@2|Bacteria,2G9XN@200795|Chloroflexi,27YVU@189775|Thermomicrobia	189775|Thermomicrobia	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158188_k127_3290549_4	1121028.ARQE01000007_gene3842	5.011e-36	141.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TVAM@28211|Alphaproteobacteria,2PKSE@255475|Aurantimonadaceae	28211|Alphaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158188_k127_3301031_6	478741.JAFS01000002_gene821	7.029e-53	197.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,37FV5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158188_k127_3301031_2	469383.Cwoe_2842	9.461e-98	330.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CP6H@84995|Rubrobacteria	84995|Rubrobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158188_k127_3301031_1	469383.Cwoe_2843	9.918e-111	369.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CP6R@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158188_k127_3301031_10	469383.Cwoe_2844	6.499e-32	141.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158188_k127_3301031_9	1298858.AUEL01000017_gene2704	1.289e-33	136.0	COG1917@1|root,COG1917@2|Bacteria,1N1ZP@1224|Proteobacteria,2UE27@28211|Alphaproteobacteria,43PMM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Ethanolamine utilisation protein EutQ	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_3301031_16	675806.VII_001225	2.078e-09	65.0	COG1695@1|root,COG1695@2|Bacteria,1RFWJ@1224|Proteobacteria,1SYA4@1236|Gammaproteobacteria,1Y2SP@135623|Vibrionales	135623|Vibrionales	K	Virulence activator alpha C-term	-	-	-	ko:K10917	ko02024,ko05111,map02024,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	PadR,Vir_act_alpha_C
SRR25158188_k127_3301031_4	1123229.AUBC01000025_gene4512	2.957e-66	248.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,3JTP7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158188_k127_3301031_14	710696.Intca_2139	3.423e-20	99.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4FHAI@85021|Intrasporangiaceae	201174|Actinobacteria	FG	Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158188_k127_3301031_11	986075.CathTA2_1818	2.927e-28	120.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli	91061|Bacilli	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158188_k127_3301031_12	561175.KB894093_gene4282	1.412e-25	120.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4EFGH@85012|Streptosporangiales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158188_k127_3301031_0	1380390.JIAT01000016_gene5627	3.227e-129	420.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158188_k127_3301031_15	1118060.CAGZ01000024_gene545	2.026e-14	78.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CVZI@84998|Coriobacteriia	84998|Coriobacteriia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158188_k127_3301031_5	350688.Clos_1249	3.727e-55	203.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,36DSP@31979|Clostridiaceae	186801|Clostridia	IM	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
SRR25158188_k127_3301031_8	1122927.KB895418_gene2866	1.896e-48	194.0	COG1011@1|root,COG1011@2|Bacteria,1V3M1@1239|Firmicutes,4IUEQ@91061|Bacilli,26XHU@186822|Paenibacillaceae	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158188_k127_3301031_7	543632.JOJL01000048_gene7295	3.592e-49	192.0	COG0500@1|root,COG2226@2|Bacteria,2IAGR@201174|Actinobacteria,4DIQB@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_3301031_13	702437.HMPREF9432_00440	1.632e-23	109.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes	1239|Firmicutes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158188_k127_3301031_3	469383.Cwoe_2851	1.643e-81	284.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158188_k127_3302932_2	1041930.Mtc_0823	1.74e-38	149.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,2N9UY@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158188_k127_3302932_3	1118059.CAHC01000017_gene531	1.601e-19	91.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3WCKQ@538999|Clostridiales incertae sedis	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158188_k127_3302932_1	292459.STH1244	1.634e-59	218.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
SRR25158188_k127_3302932_4	1123070.KB899250_gene475	5.779e-07	55.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	DUF823,DUF824,LysM,Peptidase_C39_2,TPR_1
SRR25158188_k127_3302932_0	1380390.JIAT01000014_gene6094	8.029e-64	224.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158188_k127_330915_2	469383.Cwoe_3490	4.057e-31	125.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158188_k127_330915_1	1380390.JIAT01000010_gene4569	2.431e-37	162.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4CQ8I@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158188_k127_330915_3	1122939.ATUD01000008_gene2537	2.139e-18	87.0	2AUU1@1|root,31KH5@2|Bacteria,2HPC3@201174|Actinobacteria,4CQQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_330915_0	469371.Tbis_1692	9.491e-128	430.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4E058@85010|Pseudonocardiales	201174|Actinobacteria	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158188_k127_3318368_1	1283299.AUKG01000002_gene5345	9.35e-83	286.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4CQYT@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158188_k127_3318368_0	1158050.KB895476_gene2688	1.837e-84	284.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,1W7QX@1268|Micrococcaceae	201174|Actinobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158188_k127_3323428_1	1283299.AUKG01000001_gene3557	2.674e-34	138.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,2GKVH@201174|Actinobacteria,4CRRI@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3
SRR25158188_k127_3323428_0	1048339.KB913029_gene4749	4.203e-127	424.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4ERYY@85013|Frankiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158188_k127_3323428_2	351607.Acel_1905	3.063e-31	134.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4ERVM@85013|Frankiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS
SRR25158188_k127_332675_2	684949.ATTJ01000001_gene886	4.68e-12	70.0	COG1247@1|root,COG1670@1|root,COG1247@2|Bacteria,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158188_k127_332675_1	1297570.MESS4_740038	1.609e-31	133.0	COG0454@1|root,COG0456@2|Bacteria,1R6DW@1224|Proteobacteria,2U3QR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158188_k127_332675_0	1313172.YM304_06550	9.115e-33	130.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158188_k127_3338601_3	243233.MCA2161	1.776e-47	186.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3338601_1	469383.Cwoe_2952	1.352e-85	298.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4CQ65@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_3338601_2	1122939.ATUD01000001_gene317	1.868e-79	291.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CS8K@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158188_k127_3338601_0	1463825.JNXC01000002_gene4437	1.348e-95	320.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4DYDG@85010|Pseudonocardiales	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR25158188_k127_3356208_13	1380390.JIAT01000009_gene2156	1.235e-25	108.0	COG3795@1|root,COG3795@2|Bacteria,2IMHE@201174|Actinobacteria,4CTAU@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158188_k127_3356208_1	330084.JNYZ01000029_gene9	1.873e-131	434.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4E9HU@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_3356208_12	44060.JODL01000013_gene3931	9.598e-31	129.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158188_k127_3356208_11	269797.Mbar_A2411	4.158e-39	150.0	COG1611@1|root,arCOG02431@2157|Archaea,2XXTK@28890|Euryarchaeota,2N9VX@224756|Methanomicrobia	224756|Methanomicrobia	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158188_k127_3356208_3	1380390.JIAT01000016_gene5630	4.136e-115	391.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CPW0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158188_k127_3356208_7	1394178.AWOO02000041_gene8777	2.16e-50	201.0	COG1670@1|root,COG1670@2|Bacteria,2IQW2@201174|Actinobacteria,4EJRW@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_3356208_0	469383.Cwoe_5866	1.04e-141	460.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR25158188_k127_3356208_8	1380390.JIAT01000009_gene1918	8.763e-50	192.0	COG3872@1|root,COG3872@2|Bacteria,2HQG9@201174|Actinobacteria,4CS1C@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158188_k127_3356208_4	469383.Cwoe_5867	7.362e-99	340.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4CRVV@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158188_k127_3356208_9	443218.AS9A_3070	2.478e-44	179.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria,234ZT@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158188_k127_3356208_2	246194.CHY_2201	1.89e-122	406.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158188_k127_3356208_10	1122247.C731_4973	3.161e-39	163.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,235P3@1762|Mycobacteriaceae	201174|Actinobacteria	S	Appr-1'-p processing enzyme	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158188_k127_3356208_5	562970.Btus_0192	7.498e-92	312.0	COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,2784I@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the arginase family	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158188_k127_3356208_6	485913.Krac_7548	2.637e-52	195.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158188_k127_3356208_14	300852.55773236	1.015e-16	89.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158188_k127_3362704_1	1229780.BN381_450053	1.147e-36	142.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,3UWD2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274,ko:K15408	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1,Cyt_c_ox_IV
SRR25158188_k127_3362704_0	869210.Marky_1960	5.797e-40	161.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1WIB3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
SRR25158188_k127_3362704_2	1122939.ATUD01000007_gene2049	1.797e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CPSW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_336953_3	469383.Cwoe_5514	3.524e-55	212.0	COG0642@1|root,COG3850@1|root,COG5278@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,COG5278@2|Bacteria,2INAK@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4
SRR25158188_k127_336953_1	469383.Cwoe_5381	3.196e-82	279.0	COG0745@1|root,COG0745@2|Bacteria,2IDQ0@201174|Actinobacteria,4CT58@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_336953_4	469383.Cwoe_2655	1.291e-29	125.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158188_k127_336953_2	266117.Rxyl_2308	6.51e-81	289.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158188_k127_3372161_1	1150864.MILUP08_41767	2.325e-77	267.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DAN2@85008|Micromonosporales	201174|Actinobacteria	G	Beta-glucosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158188_k127_3372161_4	1449347.JQLN01000007_gene1792	2.08e-07	63.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,2M4XJ@2063|Kitasatospora	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158188_k127_3372161_3	469383.Cwoe_1760	1.035e-30	126.0	2EN95@1|root,33FWY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3372161_2	1101188.KI912155_gene578	5.996e-43	168.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158188_k127_3372161_0	438753.AZC_4114	4.759e-89	307.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,3EXYV@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Domain of unknown function (DUF3459)	MA20_23410	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158188_k127_3373694_0	1380390.JIAT01000010_gene3468	5.607e-122	397.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4CPGK@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158188_k127_3373694_2	1123508.JH636440_gene2901	3.298e-30	126.0	COG0346@1|root,COG0346@2|Bacteria,2J081@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_3373694_1	1137271.AZUM01000008_gene2090	5.271e-75	263.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158188_k127_3376288_4	1283299.AUKG01000001_gene2719	0.0008576	48.0	2AWTN@1|root,31NQQ@2|Bacteria,2HR9K@201174|Actinobacteria,4CT69@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3376288_1	469383.Cwoe_0896	2.359e-21	108.0	COG0739@1|root,COG3409@1|root,COG0739@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,PG_binding_1,Peptidase_M23
SRR25158188_k127_3376288_0	1184607.AUCHE_05_05350	1.33e-43	177.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2IBV1@201174|Actinobacteria,4F7SC@85018|Dermatophilaceae	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR25158188_k127_3376288_2	1068980.ARVW01000001_gene6287	2.236e-08	61.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DZ55@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator, LuxR family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
SRR25158188_k127_3382587_0	1150864.MILUP08_46400	6.706e-126	415.0	COG0683@1|root,COG0683@2|Bacteria,2HU2Y@201174|Actinobacteria,4DAP5@85008|Micromonosporales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158188_k127_3382587_1	1045009.AFXQ01000011_gene445	9.61e-66	233.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,1W9SW@1268|Micrococcaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158188_k127_3387301_6	1120950.KB892757_gene6616	5.436e-47	180.0	COG0637@1|root,COG0637@2|Bacteria,2IQD3@201174|Actinobacteria,4DRPS@85009|Propionibacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158188_k127_3387301_1	266117.Rxyl_2410	1.395e-157	516.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158188_k127_3387301_0	42256.RradSPS_2485	4.465e-179	573.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158188_k127_3387301_4	572479.Hprae_1182	1.336e-81	282.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,24BFR@186801|Clostridia	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158188_k127_3387301_9	1385520.N802_10670	8.495e-05	50.0	COG3631@1|root,COG3631@2|Bacteria,2IIFS@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158188_k127_3387301_2	1210884.HG799462_gene8384	1.042e-114	383.0	COG2124@1|root,COG2124@2|Bacteria,2J1NM@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome P450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
SRR25158188_k127_3387301_3	1283299.AUKG01000003_gene687	6.822e-112	380.0	COG3276@1|root,COG3276@2|Bacteria,2GKF9@201174|Actinobacteria,4CPDU@84995|Rubrobacteria	84995|Rubrobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_3
SRR25158188_k127_3387301_5	208444.JNYY01000012_gene7798	2.303e-50	196.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria,4DZHR@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	phzM	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158188_k127_3387301_7	483219.LILAB_24505	3.232e-37	145.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158188_k127_3392731_1	886293.Sinac_5883	4.834e-171	551.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158188_k127_3392731_5	89187.ISM_03565	4.623e-31	138.0	COG0726@1|root,COG0726@2|Bacteria,1R6DC@1224|Proteobacteria	1224|Proteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3392731_2	469383.Cwoe_0093	2.298e-61	234.0	COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria,4CRDA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158188_k127_3392731_3	926554.KI912633_gene3670	1.251e-52	200.0	COG3919@1|root,COG3919@2|Bacteria	2|Bacteria	E	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C
SRR25158188_k127_3392731_8	871968.DESME_14475	2.038e-19	100.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia	186801|Clostridia	M	Group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_3392731_4	1121448.DGI_0090	3.635e-49	195.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2M8ME@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158188_k127_3392731_7	469383.Cwoe_5038	2.474e-25	119.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158188_k127_3392731_6	469383.Cwoe_5037	1.836e-27	120.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158188_k127_3392731_0	1380394.JADL01000008_gene3598	5.912e-205	652.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TSME@28211|Alphaproteobacteria,2JPWJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158188_k127_3395310_0	405948.SACE_3326	5.27e-254	795.0	COG0021@1|root,COG0021@2|Bacteria,2I36F@201174|Actinobacteria,4DZ6K@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the transketolase family	tkt3	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158188_k127_3395310_2	266117.Rxyl_1675	2.459e-90	323.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4CU2I@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158188_k127_3395310_10	1273538.G159_05945	0.0001861	55.0	COG1708@1|root,COG1708@2|Bacteria,1V16I@1239|Firmicutes,4IS0S@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
SRR25158188_k127_3395310_7	395965.Msil_2659	2.836e-20	98.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2TQPP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158188_k127_3395310_1	469383.Cwoe_4548	1.126e-203	652.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CPKI@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158188_k127_3395310_5	711393.AYRX01000008_gene4411	2.143e-35	147.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158188_k127_3395310_9	1463917.JODC01000034_gene8365	1.598e-05	56.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158188_k127_3395310_3	309799.DICTH_0982	8.067e-53	194.0	COG3707@1|root,COG3707@2|Bacteria	2|Bacteria	T	response regulator	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158188_k127_3395310_4	1157490.EL26_13680	1.74e-35	150.0	2DMXW@1|root,32UAS@2|Bacteria,1V8D1@1239|Firmicutes,4HIRE@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3395310_8	1206744.BAGL01000002_gene4232	1.567e-06	59.0	COG1051@1|root,COG1051@2|Bacteria,2GZEK@201174|Actinobacteria,4G98W@85025|Nocardiaceae	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158188_k127_3395310_6	401526.TcarDRAFT_0381	1.177e-27	123.0	COG3920@1|root,COG3920@2|Bacteria,1TRK3@1239|Firmicutes,4H25S@909932|Negativicutes	909932|Negativicutes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2
SRR25158188_k127_3409507_13	1128398.Curi_c16710	8.636e-37	152.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,267KW@186813|unclassified Clostridiales	186801|Clostridia	S	Dak2	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158188_k127_3409507_21	1033810.HLPCO_000082	2.774e-17	87.0	COG1302@1|root,COG1302@2|Bacteria,2NRIA@2323|unclassified Bacteria	2|Bacteria	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158188_k127_3409507_20	1283299.AUKG01000001_gene1286	6.702e-19	92.0	COG3837@1|root,COG3837@2|Bacteria	2|Bacteria	S	Cupin domain	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_3409507_19	469383.Cwoe_3704	2.13e-20	92.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4CQUE@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158188_k127_3409507_14	765914.ThisiDRAFT_1973	6.9e-35	143.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1WX65@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158188_k127_3409507_0	469383.Cwoe_3706	1.14e-179	580.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158188_k127_3409507_8	1283299.AUKG01000002_gene4693	3.957e-48	186.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4CQB8@84995|Rubrobacteria	84995|Rubrobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158188_k127_3409507_4	869210.Marky_1641	9.661e-74	259.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1WIP8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158188_k127_3409507_7	469383.Cwoe_3720	1.695e-53	211.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158188_k127_3409507_6	1380390.JIAT01000010_gene4191	6.885e-65	247.0	COG0144@1|root,COG0144@2|Bacteria,2GM21@201174|Actinobacteria,4CPIX@84995|Rubrobacteria	84995|Rubrobacteria	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158188_k127_3409507_16	457425.XNR_0660	1.915e-31	139.0	COG2518@1|root,COG2518@2|Bacteria,2I37N@201174|Actinobacteria	201174|Actinobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158188_k127_3409507_5	1122939.ATUD01000004_gene3768	4.078e-66	235.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CQ89@84995|Rubrobacteria	84995|Rubrobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158188_k127_3409507_12	1122939.ATUD01000009_gene2967	8.422e-37	154.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CQ1V@84995|Rubrobacteria	84995|Rubrobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158188_k127_3409507_22	1283299.AUKG01000002_gene3962	9.426e-17	92.0	2AWHW@1|root,31NEF@2|Bacteria,2HR0B@201174|Actinobacteria,4CSTX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3409507_11	1961.JOAK01000019_gene6924	2.672e-39	158.0	COG1670@1|root,COG1670@2|Bacteria,2IKZC@201174|Actinobacteria	201174|Actinobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158188_k127_3409507_10	1041146.ATZB01000006_gene2457	4.418e-43	166.0	COG3791@1|root,COG3791@2|Bacteria,1N1H2@1224|Proteobacteria,2VGCG@28211|Alphaproteobacteria,4BNIQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158188_k127_3409507_1	469383.Cwoe_3727	3.948e-146	494.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4CPGM@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158188_k127_3409507_9	68199.JNZO01000008_gene7629	1.78e-43	163.0	2CXR2@1|root,32T2F@2|Bacteria,2I2M0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3409507_18	1386089.N865_04685	9.045e-24	106.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4FHIN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158188_k127_3409507_15	795797.C497_09468	1.134e-31	130.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158188_k127_3409507_3	318424.EU78_28035	8.574e-88	302.0	COG0428@1|root,COG0428@2|Bacteria,2IBHZ@201174|Actinobacteria,238Q9@1762|Mycobacteriaceae	201174|Actinobacteria	P	Zinc permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158188_k127_3409507_17	1224164.B843_10290	5.63e-29	125.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,22M5J@1653|Corynebacteriaceae	201174|Actinobacteria	K	Mn-dependent transcriptional regulator	mntR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158188_k127_3409507_2	469383.Cwoe_3729	3.123e-90	302.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CPIK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158188_k127_3413726_1	1122939.ATUD01000007_gene2104	5.672e-118	393.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CR7R@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_3413726_8	1449346.JQMO01000003_gene5492	1.07e-19	95.0	COG1846@1|root,COG1846@2|Bacteria,2IKND@201174|Actinobacteria,2M3KF@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
SRR25158188_k127_3413726_2	748247.AZKH_0085	4.883e-105	383.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,2KVT4@206389|Rhodocyclales	206389|Rhodocyclales	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158188_k127_3413726_5	1380390.JIAT01000010_gene4431	4.357e-58	222.0	COG3629@1|root,COG3629@2|Bacteria,2GKKQ@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158188_k127_3413726_7	1267535.KB906767_gene5104	6.392e-26	122.0	COG1502@1|root,COG3266@1|root,COG1502@2|Bacteria,COG3266@2|Bacteria,3Y6X8@57723|Acidobacteria,2JKY1@204432|Acidobacteriia	204432|Acidobacteriia	I	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3413726_4	469383.Cwoe_3526	2.998e-76	272.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158188_k127_3413726_6	292459.STH749	6.065e-56	218.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158188_k127_3413726_3	105420.BBPO01000052_gene1824	6.105e-80	282.0	COG1940@1|root,COG1940@2|Bacteria,2IHJ4@201174|Actinobacteria,2NEXD@228398|Streptacidiphilus	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
SRR25158188_k127_3413726_0	1306174.JODP01000006_gene3306	2.955e-150	489.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria	201174|Actinobacteria	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
SRR25158188_k127_3413726_9	1120934.KB894427_gene1067	1.5e-08	67.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria,4E0TB@85010|Pseudonocardiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158188_k127_3423478_2	456442.Mboo_1206	5.54e-30	125.0	COG0576@1|root,arCOG04772@2157|Archaea,2XUCA@28890|Euryarchaeota,2NA0X@224756|Methanomicrobia	224756|Methanomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158188_k127_3423478_1	266117.Rxyl_0786	7.134e-102	344.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CPEG@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158188_k127_3423478_3	1122223.KB890696_gene254	5.154e-27	126.0	COG0789@1|root,COG0789@2|Bacteria,1WJ4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM MerR family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158188_k127_3423478_0	234267.Acid_0505	1.121e-282	883.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria	57723|Acidobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158188_k127_3425360_2	469383.Cwoe_4178	4.001e-68	244.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158188_k127_3425360_5	207954.MED92_12611	6.53e-23	115.0	COG1340@1|root,COG1340@2|Bacteria,1QVWN@1224|Proteobacteria,1T2KY@1236|Gammaproteobacteria,1XRT3@135619|Oceanospirillales	135619|Oceanospirillales	S	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158188_k127_3425360_6	55952.BU52_05095	3.53e-15	87.0	2DPU0@1|root,333DA@2|Bacteria,2IARZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3425360_4	384676.PSEEN4004	5.747e-26	118.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158188_k127_3425360_1	525904.Tter_0604	7.805e-74	268.0	COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria	2|Bacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283,ko:K08602	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	-
SRR25158188_k127_3425360_7	1051632.TPY_0775	4.015e-10	66.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_3425360_0	469383.Cwoe_3604	1.322e-102	360.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158188_k127_3425360_3	469383.Cwoe_0286	3.171e-48	190.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4CST8@84995|Rubrobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158188_k127_3425611_1	1120971.AUCA01000026_gene630	5.203e-69	244.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,277Y5@186823|Alicyclobacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158188_k127_3425611_2	243164.DET1348	1.527e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,34D3G@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158188_k127_3425611_3	1283299.AUKG01000001_gene1898	6.473e-32	143.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158188_k127_3425611_4	1463857.JOFZ01000017_gene2483	2.413e-18	97.0	2EDJR@1|root,337FI@2|Bacteria,2GIRI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3425611_0	1380390.JIAT01000009_gene1924	3.305e-159	516.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CRWP@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158188_k127_3436820_1	1380390.JIAT01000009_gene333	4.912e-27	126.0	COG1316@1|root,COG1316@2|Bacteria,2HPMP@201174|Actinobacteria,4CQZU@84995|Rubrobacteria	84995|Rubrobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158188_k127_3436820_0	219305.MCAG_05523	0.0	1678.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4DB0D@85008|Micromonosporales	201174|Actinobacteria	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158188_k127_3449043_15	1111479.AXAR01000002_gene1778	5.724e-05	46.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,27938@186823|Alicyclobacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158188_k127_3449043_3	469383.Cwoe_0018	1.771e-95	331.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158188_k127_3449043_5	760568.Desku_3098	1.202e-82	308.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,26106@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158188_k127_3449043_0	1380390.JIAT01000009_gene1776	3.112e-145	482.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158188_k127_3449043_4	469383.Cwoe_0016	2.001e-83	295.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CP9M@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158188_k127_3449043_2	469383.Cwoe_0015	2.57e-103	364.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158188_k127_3449043_7	469383.Cwoe_0014	7.456e-59	218.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158188_k127_3449043_13	266117.Rxyl_0025	2.477e-20	100.0	COG1716@1|root,COG1716@2|Bacteria,2HM1E@201174|Actinobacteria,4CQ7B@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158188_k127_3449043_6	1283299.AUKG01000001_gene1751	6.658e-62	230.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158188_k127_3449043_8	1283299.AUKG01000001_gene1752	1.287e-53	216.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CR9T@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158188_k127_3449043_12	469383.Cwoe_0009	3.684e-26	113.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4CS7C@84995|Rubrobacteria	84995|Rubrobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158188_k127_3449043_9	469383.Cwoe_0007	1.393e-52	190.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CQBX@84995|Rubrobacteria	84995|Rubrobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158188_k127_3449043_14	1122247.C731_3954	2.758e-15	85.0	COG2968@1|root,COG2968@2|Bacteria,2GM1U@201174|Actinobacteria,235EY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF541)	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158188_k127_3449043_10	981369.JQMJ01000004_gene5276	1.626e-31	133.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NJ3P@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158188_k127_3449043_1	469383.Cwoe_4559	5.059e-105	349.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4CRVP@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_3449043_11	469371.Tbis_2951	8.797e-28	113.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4DZTV@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158188_k127_3450253_5	469383.Cwoe_3789	1.608e-21	96.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CS4E@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_3450253_2	1273125.Rrhod_4250	1.27e-45	177.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4G0II@85025|Nocardiaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158188_k127_3450253_4	1380390.JIAT01000014_gene6036	8.546e-25	109.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4CSB0@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_3450253_1	69042.WH5701_09119	3.248e-67	248.0	COG0524@1|root,COG0524@2|Bacteria,1GBJ2@1117|Cyanobacteria,1GYYZ@1129|Synechococcus	1117|Cyanobacteria	G	pfkB family carbohydrate kinase	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158188_k127_3450253_6	1192034.CAP_8672	9.202e-20	97.0	COG2905@1|root,COG3202@1|root,COG2905@2|Bacteria,COG3202@2|Bacteria,1RERN@1224|Proteobacteria	1224|Proteobacteria	T	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158188_k127_3450253_3	1444309.JAQG01000057_gene4902	3.439e-33	135.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,26WUX@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158188_k127_3450253_0	469383.Cwoe_3777	1.107e-106	357.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CPWG@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158188_k127_3452252_5	471852.Tcur_2331	8.181e-14	74.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EH24@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158188_k127_3452252_1	1048339.KB913029_gene1098	2.78e-119	386.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4EUJK@85013|Frankiales	201174|Actinobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158188_k127_3452252_0	266117.Rxyl_2783	5.742e-145	479.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRR25158188_k127_3452252_4	929712.KI912613_gene3075	7.001e-41	157.0	COG3791@1|root,COG3791@2|Bacteria,2HP2J@201174|Actinobacteria,4CQDM@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158188_k127_3452252_3	1380390.JIAT01000011_gene2476	1.516e-46	170.0	COG0025@1|root,COG0025@2|Bacteria,2I2S7@201174|Actinobacteria,4CT3S@84995|Rubrobacteria	84995|Rubrobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158188_k127_3452252_2	469383.Cwoe_0653	3.29e-66	234.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,2GK62@201174|Actinobacteria,4CR6R@84995|Rubrobacteria	84995|Rubrobacteria	OT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158188_k127_3460578_2	1380390.JIAT01000009_gene2137	9.239e-91	317.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158188_k127_3460578_4	661478.OP10G_2366	1.062e-30	136.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ycgJ_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158188_k127_3460578_1	266117.Rxyl_1276	1.264e-142	462.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158188_k127_3460578_6	446470.Snas_0647	3.143e-25	112.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,4EYZI@85014|Glycomycetales	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158188_k127_3460578_0	316274.Haur_4207	9.7e-175	566.0	COG4770@1|root,COG4770@2|Bacteria,2GBIE@200795|Chloroflexi,3753Q@32061|Chloroflexia	32061|Chloroflexia	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158188_k127_3460578_5	1033740.CAEW01000008_gene1950	2.761e-28	121.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,26DG0@186818|Planococcaceae	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06365	CDP-OH_P_transf
SRR25158188_k127_3460578_3	1380390.JIAT01000016_gene5629	2.478e-42	173.0	COG0791@1|root,COG0791@2|Bacteria,2HPJC@201174|Actinobacteria,4CQWT@84995|Rubrobacteria	84995|Rubrobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158188_k127_3461031_6	1463845.JOIG01000006_gene1090	0.00048	51.0	COG3064@1|root,COG3064@2|Bacteria,2GMVG@201174|Actinobacteria	201174|Actinobacteria	M	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3461031_1	2002.JOEQ01000013_gene5523	8.135e-76	268.0	COG3214@1|root,COG3214@2|Bacteria,2HPNA@201174|Actinobacteria,4EHIJ@85012|Streptosporangiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158188_k127_3461031_0	471856.Jden_1347	9.64e-150	494.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158188_k127_3461031_2	42256.RradSPS_0852	1.826e-43	172.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4CQAS@84995|Rubrobacteria	84995|Rubrobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158188_k127_3461031_4	545243.BAEV01000147_gene392	7.676e-26	123.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,25BQU@186801|Clostridia,36K9C@31979|Clostridiaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158188_k127_3461031_3	1122939.ATUD01000002_gene1403	6.309e-38	161.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158188_k127_3461031_5	590998.Celf_2661	5.879e-08	59.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158188_k127_346834_0	509191.AEDB02000063_gene446	1.523e-138	451.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158188_k127_346834_4	1150399.AQYK01000002_gene2186	2.464e-07	62.0	2DPEM@1|root,331S3@2|Bacteria,2H0N7@201174|Actinobacteria,4FQGE@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158188_k127_346834_1	246969.TAM4_1127	2.502e-120	396.0	COG0714@1|root,arCOG00434@2157|Archaea,2XSZU@28890|Euryarchaeota,24353@183968|Thermococci	183968|Thermococci	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158188_k127_346834_3	1120950.KB892753_gene6092	2.657e-55	218.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria,4DQW5@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158188_k127_346834_5	1155718.KB891911_gene1308	4.417e-07	61.0	2EFF7@1|root,33981@2|Bacteria,2IFB2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_346834_2	1169161.KB897736_gene5342	2.341e-72	257.0	2A05M@1|root,30N8E@2|Bacteria,2ICIN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
SRR25158188_k127_346834_7	1231185.BAMP01000125_gene935	0.0009522	42.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,43JTJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158188_k127_348005_1	1283299.AUKG01000001_gene1867	3.163e-73	261.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4CPVH@84995|Rubrobacteria	84995|Rubrobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158188_k127_348005_5	1122223.KB890688_gene1419	9.275e-15	83.0	COG1587@1|root,COG1587@2|Bacteria,1WJ3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRR25158188_k127_348005_2	1121346.KB899811_gene1587	3.656e-59	216.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,26RBP@186822|Paenibacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158188_k127_348005_0	644966.Tmar_1263	3.512e-84	303.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158188_k127_348005_4	1232410.KI421412_gene412	1.877e-20	102.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158188_k127_348005_3	469383.Cwoe_5876	6.685e-43	168.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CSM2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158188_k127_348005_6	1283299.AUKG01000001_gene1874	2.033e-13	72.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria,4CQ9M@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158188_k127_3484298_1	1463856.JOHY01000001_gene433	1.126e-69	256.0	COG2508@1|root,COG2508@2|Bacteria,2GJWJ@201174|Actinobacteria	201174|Actinobacteria	QT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158188_k127_3484298_2	330084.JNYZ01000015_gene5954	1.388e-64	236.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria	201174|Actinobacteria	E	Dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158188_k127_3484298_3	1283299.AUKG01000001_gene1262	1.385e-49	184.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_3484298_0	469383.Cwoe_1782	6.887e-72	252.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4CPNS@84995|Rubrobacteria	84995|Rubrobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158188_k127_3484298_4	1380390.JIAT01000014_gene6231	2.202e-14	76.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria,4CQ51@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3496013_7	1051632.TPY_1473	1.414e-66	243.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR25158188_k127_3496013_4	1123023.JIAI01000001_gene6922	2.02e-86	293.0	COG3342@1|root,COG3342@2|Bacteria,2HWBG@201174|Actinobacteria,4E7BZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
SRR25158188_k127_3496013_19	146922.JOFU01000020_gene2499	0.0005605	51.0	COG0662@1|root,COG0662@2|Bacteria,2ICZ9@201174|Actinobacteria	201174|Actinobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_3496013_17	1041146.ATZB01000002_gene5091	5.534e-06	57.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaF2	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158188_k127_3496013_10	1283299.AUKG01000003_gene247	3.562e-42	162.0	2FHCG@1|root,3496S@2|Bacteria,2H7A4@201174|Actinobacteria,4CQPX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158188_k127_3496013_18	1380394.JADL01000014_gene204	9.226e-06	56.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,2JQ09@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.338	ko:K16844	ko00270,ko01120,map00270,map01120	-	R07137	RC00031	ko00000,ko00001,ko01000	-	-	-	Ldh_2
SRR25158188_k127_3496013_8	685727.REQ_05350	2.317e-56	205.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4FTZ0@85025|Nocardiaceae	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158188_k127_3496013_2	58123.JOFJ01000015_gene4532	8.444e-106	357.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4EHYM@85012|Streptosporangiales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158188_k127_3496013_0	1380356.JNIK01000014_gene3356	1.518e-228	725.0	COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158188_k127_3496013_14	446465.Bfae_08820	1.035e-22	103.0	2EJ8W@1|root,33D03@2|Bacteria,2GW9I@201174|Actinobacteria,4FDYS@85020|Dermabacteraceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1660
SRR25158188_k127_3496013_16	1449346.JQMO01000003_gene2919	1.802e-09	70.0	COG3291@1|root,COG3291@2|Bacteria,2H2CR@201174|Actinobacteria,2M467@2063|Kitasatospora	201174|Actinobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3496013_15	1283299.AUKG01000002_gene4757	1.444e-19	103.0	COG4733@1|root,COG4733@2|Bacteria,2I7QH@201174|Actinobacteria,4CS4B@84995|Rubrobacteria	84995|Rubrobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3496013_3	1283299.AUKG01000002_gene4555	3.687e-101	334.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158188_k127_3496013_1	525904.Tter_2101	2.452e-138	453.0	COG0741@1|root,COG3023@1|root,COG0741@2|Bacteria,COG3023@2|Bacteria,2NQTN@2323|unclassified Bacteria	2|Bacteria	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SLT,VCBS
SRR25158188_k127_3496013_9	1283299.AUKG01000001_gene1985	3.151e-51	191.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158188_k127_3496013_5	1283299.AUKG01000001_gene3257	5.089e-68	244.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4CS23@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158188_k127_3496013_6	469383.Cwoe_5827	1.151e-67	243.0	COG3481@1|root,COG3481@2|Bacteria,2HPRJ@201174|Actinobacteria,4CR4T@84995|Rubrobacteria	84995|Rubrobacteria	S	OB-fold nucleic acid binding domain	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
SRR25158188_k127_3496013_12	36809.MAB_0415	4.444e-29	132.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,233AP@1762|Mycobacteriaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_3496013_11	351607.Acel_1794	4.278e-42	157.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4ET2T@85013|Frankiales	201174|Actinobacteria	T	low molecular weight	arsC	-	1.20.4.1,2.8.4.2	ko:K03325,ko:K03741,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	LMWPc
SRR25158188_k127_3496013_13	591167.Sfla_6188	7.342e-27	112.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158188_k127_3505581_3	765420.OSCT_0145	4.171e-52	186.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,374XT@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158188_k127_3505581_5	1070774.J07HN4v3_00340	8.223e-11	66.0	arCOG08975@1|root,arCOG08975@2157|Archaea,2Y04U@28890|Euryarchaeota,23Y2M@183963|Halobacteria	183963|Halobacteria	S	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158188_k127_3505581_1	469383.Cwoe_2902	1.601e-79	273.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
SRR25158188_k127_3505581_2	1283299.AUKG01000001_gene3214	7.054e-64	237.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2H432@201174|Actinobacteria,4CR80@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_3505581_6	1123269.NX02_09445	7.808e-10	70.0	COG0392@1|root,COG0392@2|Bacteria,1R468@1224|Proteobacteria,2U0QT@28211|Alphaproteobacteria,2K65B@204457|Sphingomonadales	204457|Sphingomonadales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158188_k127_3505581_4	219305.MCAG_00765	5.106e-22	104.0	2C8AY@1|root,331RE@2|Bacteria,2HPG4@201174|Actinobacteria,4DFMS@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3505581_0	469383.Cwoe_2903	8.36e-117	387.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158188_k127_3508545_2	1157637.KB892135_gene3404	2.245e-125	406.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158188_k127_3508545_1	1382356.JQMP01000003_gene2056	5.956e-134	443.0	COG1653@1|root,COG1653@2|Bacteria,2G6WT@200795|Chloroflexi,27Z46@189775|Thermomicrobia	189775|Thermomicrobia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10236	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	SBP_bac_1
SRR25158188_k127_3508545_3	479434.Sthe_1812	6.583e-111	366.0	COG1175@1|root,COG1175@2|Bacteria,2G8HC@200795|Chloroflexi,27YT8@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10237	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	BPD_transp_1
SRR25158188_k127_3508545_4	1382356.JQMP01000003_gene2058	1.325e-102	347.0	COG0395@1|root,COG0395@2|Bacteria,2G6M8@200795|Chloroflexi,27Z03@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10238	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	BPD_transp_1
SRR25158188_k127_3508545_0	1380390.JIAT01000009_gene1538	5.667e-166	530.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158188_k127_3508545_5	1283299.AUKG01000004_gene1071	2.471e-30	123.0	2AWAN@1|root,31N67@2|Bacteria,2HQU1@201174|Actinobacteria,4CSYP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3508658_1	479434.Sthe_2397	2.35e-28	129.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158188_k127_3508658_0	467200.ACFA01000003_gene1759	9.63e-83	278.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158188_k127_3509775_3	196162.Noca_4642	0.0002323	46.0	28THW@1|root,2ZFRR@2|Bacteria,2GQMQ@201174|Actinobacteria,4DW1X@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3509775_0	298655.KI912266_gene2771	6.735e-66	241.0	28KBH@1|root,2Z9YH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3509775_1	690850.Desaf_2499	1.705e-52	206.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158188_k127_3509775_2	1122611.KB903941_gene2267	3.201e-33	136.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4EIRS@85012|Streptosporangiales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158188_k127_3511183_2	469383.Cwoe_4248	8.112e-39	152.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158188_k127_3511183_1	235985.BBPN01000032_gene221	6.895e-84	317.0	COG0739@1|root,COG4934@1|root,COG0739@2|Bacteria,COG4934@2|Bacteria,2H5BC@201174|Actinobacteria,2NFF9@228398|Streptacidiphilus	201174|Actinobacteria	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
SRR25158188_k127_3511183_3	1416759.AYMR01000007_gene697	1.206e-36	162.0	COG3391@1|root,COG3468@1|root,COG4870@1|root,COG4932@1|root,COG3391@2|Bacteria,COG3468@2|Bacteria,COG4870@2|Bacteria,COG4932@2|Bacteria,2HCJX@201174|Actinobacteria,4FTDJ@85023|Microbacteriaceae	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158188_k127_3511183_0	1394178.AWOO02000009_gene4251	1.96e-93	316.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4EGAQ@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	wcoR	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158188_k127_3511937_2	266779.Meso_0693	1.975e-20	92.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,43JTJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158188_k127_3511937_3	1403819.BATR01000086_gene2522	3.077e-20	101.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yhhY	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158188_k127_3511937_0	469383.Cwoe_4666	5.363e-110	372.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158188_k127_3511937_1	1380390.JIAT01000009_gene1522	1.672e-35	156.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4CRDF@84995|Rubrobacteria	84995|Rubrobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3513853_5	471852.Tcur_2105	3.841e-64	222.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4EG5S@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158188_k127_3513853_7	1380390.JIAT01000013_gene34	2.655e-51	188.0	2ASH4@1|root,31HXG@2|Bacteria,2HMFJ@201174|Actinobacteria,4CQBD@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_3513853_14	983917.RGE_40480	0.0004406	51.0	28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,2VKW4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR25158188_k127_3513853_6	266117.Rxyl_1317	5.119e-58	221.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CQEG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158188_k127_3513853_3	42256.RradSPS_1294	2.748e-83	283.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158188_k127_3513853_13	1122223.KB890701_gene2173	1.251e-15	91.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	ycf48	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
SRR25158188_k127_3513853_8	469383.Cwoe_3179	1.285e-42	161.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CQCR@84995|Rubrobacteria	84995|Rubrobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158188_k127_3513853_9	469383.Cwoe_3180	1.351e-37	150.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CQA9@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158188_k127_3513853_1	1304880.JAGB01000002_gene1856	6.66e-119	400.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158188_k127_3513853_12	1449048.JQKU01000005_gene4604	2.522e-17	85.0	COG0237@1|root,COG0237@2|Bacteria,2IIS6@201174|Actinobacteria,239DW@1762|Mycobacteriaceae	201174|Actinobacteria	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
SRR25158188_k127_3513853_11	1306174.JODP01000006_gene3796	1.65e-30	135.0	2A71N@1|root,30VX0@2|Bacteria,2H0K2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3513853_10	929712.KI912613_gene3321	3.592e-34	136.0	2AW02@1|root,31MUH@2|Bacteria,2HQH7@201174|Actinobacteria,4CS2A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3513853_2	1304874.JAFY01000002_gene787	5.208e-112	374.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	cefD	-	5.1.1.17	ko:K04127,ko:K11325,ko:K21174	ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130	M00673,M00825	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158188_k127_3513853_0	1268072.PSAB_18140	7.349e-130	437.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
SRR25158188_k127_3513853_4	469383.Cwoe_3187	1.574e-76	263.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158188_k127_3525457_0	479432.Sros_7481	4.681e-266	834.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4EGA4@85012|Streptosporangiales	201174|Actinobacteria	OP	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158188_k127_3525457_1	1380390.JIAT01000009_gene340	3.258e-209	659.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CP9Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158188_k127_3525882_5	1283299.AUKG01000002_gene3794	2.72e-24	106.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_3525882_2	590998.Celf_1110	8.386e-32	138.0	COG0572@1|root,COG0572@2|Bacteria,2GMCP@201174|Actinobacteria	201174|Actinobacteria	F	PFAM AIG2 family protein	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158188_k127_3525882_1	471852.Tcur_3068	7.521e-59	226.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4EHYE@85012|Streptosporangiales	201174|Actinobacteria	L	GIY-YIG type nucleases (URI domain)	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158188_k127_3525882_4	1122609.AUGT01000005_gene1614	4.597e-27	119.0	COG0791@1|root,COG0791@2|Bacteria,2IFT3@201174|Actinobacteria,4DRZD@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	NLPC_P60
SRR25158188_k127_3525882_0	1150599.MPHLEI_07282	1.743e-95	341.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,2370B@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_3525882_3	1209984.BN978_03765	1.151e-28	123.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,2370B@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_3528329_3	42256.RradSPS_0866	1.896e-107	358.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4CP76@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158188_k127_3528329_16	1219084.AP014508_gene1372	0.0001924	55.0	COG2804@1|root,COG2804@2|Bacteria,2GCDW@200918|Thermotogae	200918|Thermotogae	NU	PFAM type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158188_k127_3528329_4	1401067.HMPREF0872_02250	3.36e-104	365.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158188_k127_3528329_8	1283283.ATXA01000021_gene2872	1.056e-62	223.0	COG0412@1|root,COG0412@2|Bacteria,2HTVD@201174|Actinobacteria,4EUUV@85013|Frankiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158188_k127_3528329_6	1179773.BN6_38450	5.677e-86	287.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria,4E2WN@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158188_k127_3528329_11	1122182.KB903823_gene1353	1.079e-40	158.0	COG3795@1|root,COG3795@2|Bacteria,2IKXM@201174|Actinobacteria,4DE0G@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158188_k127_3528329_1	266117.Rxyl_2718	1.657e-246	775.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,4CPGT@84995|Rubrobacteria	84995|Rubrobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158188_k127_3528329_2	882083.SacmaDRAFT_1089	9.326e-143	465.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4E201@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158188_k127_3528329_0	266117.Rxyl_2720	0.0	1146.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4CU1R@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
SRR25158188_k127_3528329_13	469378.Ccur_09700	5.824e-20	89.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CWGB@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158188_k127_3528329_15	264732.Moth_2474	9.923e-07	55.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158188_k127_3528329_7	1380390.JIAT01000011_gene2554	1.493e-71	248.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158188_k127_3528329_9	1380390.JIAT01000011_gene2555	1.988e-62	216.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4CQ3Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158188_k127_3528329_5	469383.Cwoe_1324	5.145e-99	336.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158188_k127_3528329_12	345219.Bcoa_1176	2.54e-29	127.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158188_k127_3528329_10	1040989.AWZU01000014_gene4558	4.46e-41	154.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,3JYT4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158188_k127_3528329_14	1121468.AUBR01000065_gene960	1.277e-09	61.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,42ETP@68295|Thermoanaerobacterales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158188_k127_3532490_0	1150864.MILUP08_42994	5.855e-121	396.0	COG0798@1|root,COG0798@2|Bacteria,2GJ4H@201174|Actinobacteria,4DAP2@85008|Micromonosporales	201174|Actinobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
SRR25158188_k127_3532490_3	290397.Adeh_1024	1.828e-32	130.0	COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,42VTU@68525|delta/epsilon subdivisions,2WRGJ@28221|Deltaproteobacteria,2YVHK@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158188_k127_3532490_5	1173024.KI912149_gene5846	3.709e-14	79.0	COG0640@1|root,COG0640@2|Bacteria,1G7VI@1117|Cyanobacteria,1JM9G@1189|Stigonemataceae	1117|Cyanobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158188_k127_3532490_1	1032480.MLP_37580	5.193e-95	319.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DNPK@85009|Propionibacteriales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158188_k127_3532490_4	408672.NBCG_04239	2.137e-28	118.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4DRUV@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158188_k127_3532490_6	631362.Thi970DRAFT_04574	2.06e-05	56.0	COG1433@1|root,COG1433@2|Bacteria,1N8RP@1224|Proteobacteria,1SIA9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
SRR25158188_k127_3532490_2	685778.AORL01000015_gene2449	3.033e-81	273.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,2K5JQ@204457|Sphingomonadales	204457|Sphingomonadales	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158188_k127_3533947_4	309798.COPRO5265_0834	7.463e-46	173.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,42GF5@68295|Thermoanaerobacterales	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158188_k127_3533947_6	1123229.AUBC01000001_gene1531	5.836e-18	88.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,2TW0S@28211|Alphaproteobacteria,3K703@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158188_k127_3533947_7	1380393.JHVP01000005_gene3682	1.009e-09	69.0	COG1295@1|root,COG1295@2|Bacteria,2H11D@201174|Actinobacteria,4EW55@85013|Frankiales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158188_k127_3533947_3	1157637.KB892095_gene2796	2.035e-50	203.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158188_k127_3533947_1	105420.BBPO01000009_gene2170	2.819e-101	345.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,2NHG4@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_3533947_0	1121272.KB903249_gene2121	1.912e-110	372.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,4DCCG@85008|Micromonosporales	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_3533947_5	1237500.ANBA01000007_gene2922	1.691e-28	123.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4EI7R@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158188_k127_3533947_2	861299.J421_3474	5.321e-53	196.0	COG4448@1|root,COG4448@2|Bacteria,1ZTG2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158188_k127_3535931_0	1192034.CAP_1613	1.622e-150	489.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2YU0Z@29|Myxococcales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158188_k127_3535931_1	1207063.P24_06501	1.075e-56	204.0	COG4106@1|root,COG4106@2|Bacteria,1N21Y@1224|Proteobacteria,2UES4@28211|Alphaproteobacteria,2JX3B@204441|Rhodospirillales	204441|Rhodospirillales	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_3547901_5	471855.Shel_10080	1.005e-40	154.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CUK9@84998|Coriobacteriia	84998|Coriobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158188_k127_3547901_4	469383.Cwoe_3689	3.914e-48	184.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CPZ4@84995|Rubrobacteria	84995|Rubrobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158188_k127_3547901_9	42256.RradSPS_1388	1.449e-23	102.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158188_k127_3547901_1	525904.Tter_0052	3.791e-77	273.0	COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158188_k127_3547901_10	1304885.AUEY01000008_gene2068	1.821e-19	89.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,2MMB1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158188_k127_3547901_6	909613.UO65_4805	2.441e-40	157.0	COG0454@1|root,COG0456@2|Bacteria,2GKQU@201174|Actinobacteria,4E5CF@85010|Pseudonocardiales	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158188_k127_3547901_7	469383.Cwoe_3693	1.262e-30	134.0	COG1399@1|root,COG1399@2|Bacteria,2HQSM@201174|Actinobacteria,4CSGR@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158188_k127_3547901_2	1379270.AUXF01000007_gene926	5.146e-59	217.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_3547901_0	345341.KUTG_00776	1.388e-77	270.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158188_k127_3547901_8	561175.KB894093_gene2945	1.898e-28	129.0	COG1695@1|root,COG1695@2|Bacteria,2GRHC@201174|Actinobacteria,4EK15@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR25158188_k127_3547901_11	1160718.SU9_15247	2.059e-05	54.0	2CJ9E@1|root,2ZKS1@2|Bacteria,2H1G0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3547901_3	929712.KI912613_gene4214	1.429e-53	192.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3563424_1	926550.CLDAP_37690	1.183e-21	104.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158188_k127_3563424_0	330214.NIDE3016	1.45e-75	263.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158188_k127_3563424_2	1038858.AXBA01000009_gene572	3.499e-07	59.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria	1224|Proteobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	exoQ	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
SRR25158188_k127_358992_6	405566.lhv_2029	8.111e-08	53.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae	91061|Bacilli	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09895	ADSL_C,Lyase_1
SRR25158188_k127_358992_5	1283283.ATXA01000004_gene4337	9.419e-09	67.0	2BY2H@1|root,32R2G@2|Bacteria,2H4RJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_358992_4	1380390.JIAT01000009_gene1491	1.677e-46	171.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CQ7C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158188_k127_358992_0	1122609.AUGT01000028_gene2668	7.276e-115	385.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4DN4W@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158188_k127_358992_8	1120934.KB894420_gene2293	0.0002529	52.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4E2J8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_358992_2	1283299.AUKG01000001_gene2912	9.7e-83	286.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158188_k127_358992_7	426716.JOAJ01000001_gene1656	1.665e-07	62.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4FXYC@85025|Nocardiaceae	201174|Actinobacteria	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158188_k127_358992_3	1122622.ATWJ01000009_gene3377	1.537e-50	188.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4FE9T@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158188_k127_358992_1	222534.KB893714_gene1636	2.202e-102	341.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4ERUX@85013|Frankiales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158188_k127_3596209_2	1298863.AUEP01000009_gene197	0.0001543	52.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DNY6@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158188_k127_3596209_1	1280673.AUJJ01000010_gene2440	9.921e-13	78.0	COG1102@1|root,COG1102@2|Bacteria,1V30Q@1239|Firmicutes,24G07@186801|Clostridia,4BYWR@830|Butyrivibrio	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
SRR25158188_k127_3596209_0	1040989.AWZU01000035_gene1745	1.103e-15	79.0	COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2TSKK@28211|Alphaproteobacteria,3JRJT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	MA20_21430	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158188_k127_3599460_0	1283283.ATXA01000001_gene977	2.951e-147	477.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4ES0F@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158188_k127_3599460_1	1216932.CM240_0533	3.974e-05	51.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,36KFP@31979|Clostridiaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158188_k127_3620844_0	1380390.JIAT01000011_gene2343	1.727e-275	864.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158188_k127_3620844_8	370438.PTH_1098	2.189e-05	53.0	COG1434@1|root,COG1434@2|Bacteria,1VB45@1239|Firmicutes,24RV0@186801|Clostridia,262UT@186807|Peptococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158188_k127_3620844_3	768704.Desmer_4317	8.928e-41	166.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia,261RR@186807|Peptococcaceae	186801|Clostridia	S	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158188_k127_3620844_5	469383.Cwoe_1499	2.903e-18	96.0	COG1714@1|root,COG1714@2|Bacteria,2HRTA@201174|Actinobacteria,4CTWR@84995|Rubrobacteria	84995|Rubrobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158188_k127_3620844_6	367299.JOEE01000001_gene1916	4.065e-17	94.0	2CEFP@1|root,2ZGIZ@2|Bacteria,2GT06@201174|Actinobacteria,4FJJE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3620844_1	929712.KI912613_gene1690	1.276e-130	432.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,4CR3I@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158188_k127_3620844_2	929712.KI912613_gene1691	6.744e-74	256.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4CT1X@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_3620844_4	1210045.ALNP01000012_gene1528	4.313e-32	126.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ggt1	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158188_k127_3629569_0	693986.MOC_5081	1.222e-100	350.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,1JTFZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_7,PAS_8
SRR25158188_k127_3629569_1	1459636.NTE_03327	8.603e-08	61.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3629569_2	1183438.GKIL_1366	1.605e-05	57.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	ASH,Cadherin-like,DUF1573,TIG,VWA
SRR25158188_k127_3629569_3	715226.ABI_16890	6.615e-05	51.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,2KGMB@204458|Caulobacterales	204458|Caulobacterales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158188_k127_3634770_2	1380390.JIAT01000009_gene2024	2.007e-07	58.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
SRR25158188_k127_3634770_1	1123023.JIAI01000020_gene2094	1.192e-77	274.0	COG0387@1|root,COG0387@2|Bacteria,2IA57@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium calcium exchanger	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158188_k127_3634770_0	1380390.JIAT01000010_gene4014	1.909e-91	306.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158188_k127_3638130_0	1128421.JAGA01000002_gene1815	1.425e-94	320.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158188_k127_3638130_1	1380390.JIAT01000011_gene2625	2.396e-51	198.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CQ4E@84995|Rubrobacteria	84995|Rubrobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158188_k127_3638130_2	469383.Cwoe_2525	7.019e-47	173.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_3644337_2	1384057.CD33_18565	2.355e-72	252.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,3IW8J@400634|Lysinibacillus	91061|Bacilli	S	YmdB-like protein	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
SRR25158188_k127_3644337_0	1380390.JIAT01000009_gene1808	9.694e-108	375.0	2AU3I@1|root,31JPZ@2|Bacteria,2H277@201174|Actinobacteria,4CQ2S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3644337_5	1122939.ATUD01000013_gene903	1.5e-32	138.0	COG2246@1|root,COG2246@2|Bacteria,2HR1U@201174|Actinobacteria,4CSWB@84995|Rubrobacteria	84995|Rubrobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158188_k127_3644337_4	1122197.ATWI01000008_gene2792	3.392e-52	194.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158188_k127_3644337_1	469383.Cwoe_5938	3.917e-77	281.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158188_k127_3644337_7	1123024.AUII01000027_gene2636	1.347e-07	57.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.8,1.8.1.9	ko:K00384,ko:K03671,ko:K03672	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158188_k127_3644337_3	469383.Cwoe_2193	2.483e-61	218.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158188_k127_3645842_1	1283283.ATXA01000013_gene3489	4.089e-130	426.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	Beta_helix
SRR25158188_k127_3645842_7	1205680.CAKO01000010_gene3860	1.477e-46	181.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TUT7@28211|Alphaproteobacteria,2JQQI@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158188_k127_3645842_4	504474.cu1440	2.046e-63	226.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,22JPX@1653|Corynebacteriaceae	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_3645842_5	266117.Rxyl_0379	5.865e-60	228.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	201174|Actinobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	mtrB	-	2.7.13.3	ko:K02484,ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_8,Response_reg
SRR25158188_k127_3645842_6	469383.Cwoe_5804	6.324e-56	205.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4CT3E@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158188_k127_3645842_10	1122939.ATUD01000017_gene4008	2.203e-10	72.0	2ATZV@1|root,31JJQ@2|Bacteria,2HNRB@201174|Actinobacteria,4CPYQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3645842_11	1236902.ANAS01000004_gene3696	1.064e-09	69.0	2BY2H@1|root,32R2G@2|Bacteria,2H4RJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3645842_0	1380390.JIAT01000009_gene2065	1.532e-159	518.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRC3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_3645842_3	1283299.AUKG01000002_gene3805	9.604e-107	353.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CPVA@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158188_k127_3645842_2	469383.Cwoe_4667	5.531e-124	414.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CRHI@84995|Rubrobacteria	84995|Rubrobacteria	D	Tubulin/FtsZ family, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C,Tubulin
SRR25158188_k127_3645842_9	1463854.JOHT01000014_gene4987	1.282e-15	89.0	COG0778@1|root,COG0778@2|Bacteria,2IPN9@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158188_k127_3645842_8	1157634.KB912955_gene5235	1.741e-19	94.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3649106_2	56780.SYN_01129	1.382e-26	111.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WJEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	JM	PFAM Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
SRR25158188_k127_3649106_0	357808.RoseRS_4076	5.954e-54	202.0	COG0451@1|root,COG0451@2|Bacteria,2GBGX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158188_k127_3649106_3	1121028.ARQE01000008_gene2431	0.0003873	51.0	COG0438@1|root,COG1216@1|root,COG3754@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3754@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_41,Glycos_transf_2
SRR25158188_k127_3649106_1	983917.RGE_04390	1.779e-35	147.0	COG0463@1|root,COG0463@2|Bacteria,1QZZ4@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158188_k127_3653215_0	1380390.JIAT01000011_gene2623	1.298e-111	372.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CPFU@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158188_k127_3653215_3	266117.Rxyl_2310	2.048e-45	173.0	COG0546@1|root,COG0546@2|Bacteria,2I9FC@201174|Actinobacteria,4CTYC@84995|Rubrobacteria	84995|Rubrobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158188_k127_3653215_1	266117.Rxyl_0070	3.621e-109	381.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158188_k127_3653215_5	1410625.JHWK01000004_gene787	1.157e-41	162.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,27IG7@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158188_k127_3653215_2	1380390.JIAT01000010_gene3711	1.215e-57	204.0	COG1633@1|root,COG1633@2|Bacteria,2IEYT@201174|Actinobacteria,4CQ9W@84995|Rubrobacteria	201174|Actinobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3653215_6	1125863.JAFN01000001_gene3323	4.656e-39	148.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158188_k127_3653215_4	1380390.JIAT01000011_gene2615	3.925e-43	161.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158188_k127_3674274_2	867845.KI911784_gene3231	1.556e-53	191.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,37527@32061|Chloroflexia	32061|Chloroflexia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158188_k127_3674274_4	1123368.AUIS01000016_gene2538	1.818e-06	59.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DM	COG0739 Membrane proteins related to metalloendopeptidases	nlpD	GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944	-	ko:K06194,ko:K12943	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
SRR25158188_k127_3674274_0	1283299.AUKG01000003_gene556	1.869e-66	256.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158188_k127_3674274_1	929712.KI912613_gene2658	1.153e-60	221.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158188_k127_3674274_3	58123.JOFJ01000002_gene2586	6.817e-29	129.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4EIUY@85012|Streptosporangiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158188_k127_368015_3	1303518.CCALI_01127	9.727e-46	175.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
SRR25158188_k127_368015_1	1242864.D187_007083	2.138e-88	300.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria	1224|Proteobacteria	IQ	Short-chain dehydrogenase reductase, SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158188_k127_368015_0	309801.trd_1049	4.145e-127	438.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SRR25158188_k127_368015_2	1283299.AUKG01000001_gene3082	1.261e-82	288.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158188_k127_368015_4	1134413.ANNK01000159_gene3626	3.721e-06	53.0	2A61F@1|root,30UTS@2|Bacteria,1UB8J@1239|Firmicutes,4IMMA@91061|Bacilli,1ZKEM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3687692_2	644966.Tmar_0646	3.439e-53	207.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,25BFP@186801|Clostridia	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158188_k127_3687692_1	749927.AMED_7935	1.432e-53	195.0	COG0500@1|root,COG2226@2|Bacteria,2IPTP@201174|Actinobacteria,4EAQM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158188_k127_3687692_3	519442.Huta_0481	1.707e-50	198.0	COG3919@1|root,arCOG06897@2157|Archaea,2XVV0@28890|Euryarchaeota	28890|Euryarchaeota	S	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATPgrasp_Ter
SRR25158188_k127_3687692_5	211114.JOEF01000001_gene7194	4.696e-28	117.0	COG1586@1|root,COG1586@2|Bacteria,2IKJD@201174|Actinobacteria,4EDG7@85010|Pseudonocardiales	201174|Actinobacteria	E	S-adenosylmethionine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	AdoMet_dc,PP-binding
SRR25158188_k127_3687692_0	446470.Snas_1462	2.659e-66	240.0	COG1568@1|root,COG1568@2|Bacteria,2GY7U@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function DUF43	-	-	2.5.1.128	ko:K07057	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,DUF43
SRR25158188_k127_3687692_4	263358.VAB18032_00985	5.085e-38	145.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4D9RZ@85008|Micromonosporales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158188_k127_3699685_1	1120949.KB903295_gene2225	2.213e-96	332.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D96C@85008|Micromonosporales	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,GerE,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR25158188_k127_3699685_2	266117.Rxyl_0884	5.76e-65	228.0	COG0662@1|root,COG0662@2|Bacteria,2I5KR@201174|Actinobacteria,4CTK8@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_3699685_3	994479.GL877879_gene5873	1.251e-05	57.0	2CG61@1|root,33W7P@2|Bacteria,2IRYJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_3699685_0	1121472.AQWN01000005_gene2381	3.187e-184	598.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,261CF@186807|Peptococcaceae	186801|Clostridia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158188_k127_3741461_1	1379698.RBG1_1C00001G0299	2.92e-62	217.0	COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria	2|Bacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	LysM,Sod_Fe_C,Sod_Fe_N
SRR25158188_k127_3741461_2	861299.J421_3236	6.878e-36	150.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158188_k127_3741461_0	1283299.AUKG01000001_gene2450	4.268e-91	317.0	COG1469@1|root,COG1469@2|Bacteria,2HPYB@201174|Actinobacteria,4CRDI@84995|Rubrobacteria	84995|Rubrobacteria	S	Type I GTP cyclohydrolase folE2	-	-	-	-	-	-	-	-	-	-	-	-	GCHY-1
SRR25158188_k127_3741461_3	1089455.MOPEL_022_00130	3.413e-15	82.0	COG0642@1|root,COG2205@2|Bacteria,2GMB9@201174|Actinobacteria,4F7FV@85018|Dermatophilaceae	201174|Actinobacteria	T	PAS domain	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158188_k127_3753610_2	469383.Cwoe_3490	3.502e-54	199.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158188_k127_3753610_1	469383.Cwoe_3489	5.677e-59	211.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CQ53@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158188_k127_3753610_0	929712.KI912613_gene2824	1.009e-97	331.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_385957_1	326427.Cagg_1046	1.038e-128	420.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi,3751Y@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD1	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158188_k127_385957_3	1094715.CM001373_gene439	4.239e-30	136.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1JCT5@118969|Legionellales	118969|Legionellales	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158188_k127_385957_0	101510.RHA1_ro05914	1.938e-131	437.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4FXA1@85025|Nocardiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158188_k127_385957_2	1122939.ATUD01000010_gene2927	1.967e-88	300.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4CR3F@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158188_k127_390505_2	1120972.AUMH01000008_gene2086	1.888e-06	50.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,PQQ_2
SRR25158188_k127_390505_1	1385520.N802_13100	6.438e-10	64.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	1.13.11.24	ko:K07155	-	-	-	-	ko00000,ko01000	-	-	-	Cupin_2
SRR25158188_k127_390505_0	1122939.ATUD01000007_gene1992	7.785e-250	789.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158188_k127_392969_2	1123389.ATXJ01000002_gene1478	3.886e-164	542.0	COG0173@1|root,COG0173@2|Bacteria,1WIEA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158188_k127_392969_6	1121468.AUBR01000003_gene627	7.213e-106	357.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,42FQT@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158188_k127_392969_8	1122939.ATUD01000005_gene2595	6e-50	192.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4CQ06@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158188_k127_392969_13	1283299.AUKG01000001_gene2463	1.005e-19	93.0	COG1917@1|root,COG1917@2|Bacteria,2HN4T@201174|Actinobacteria,4CQJ2@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_392969_4	266117.Rxyl_0585	1.64e-145	473.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4CQ30@84995|Rubrobacteria	84995|Rubrobacteria	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	-	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158188_k127_392969_0	562970.Btus_0928	3.745e-246	771.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,2782U@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158188_k127_392969_3	1183438.GKIL_2511	6.667e-163	527.0	COG2986@1|root,COG2986@2|Bacteria,1G3FJ@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	4.3.1.24,4.3.1.3	ko:K01745,ko:K10775	ko00340,ko00360,ko00940,ko01100,ko01110,map00340,map00360,map00940,map01100,map01110	M00039,M00045,M00137,M00350	R00697,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158188_k127_392969_7	1380390.JIAT01000017_gene5312	4.623e-61	223.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CPTU@84995|Rubrobacteria	84995|Rubrobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158188_k127_392969_10	886293.Sinac_0498	2.301e-35	149.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung	-	3.2.2.27	ko:K03648,ko:K21929	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
SRR25158188_k127_392969_9	28444.JODQ01000006_gene545	1.072e-41	160.0	COG2227@1|root,COG2227@2|Bacteria,2GTJX@201174|Actinobacteria,4EJSA@85012|Streptosporangiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158188_k127_392969_5	42256.RradSPS_2180	4.66e-143	474.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_392969_1	469383.Cwoe_2921	2.211e-185	606.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPT4@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_392969_11	1178537.BA1_11689	3.048e-21	107.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus	91061|Bacilli	O	Peptidase M48	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158188_k127_392969_12	1463864.JOGO01000025_gene2857	5.923e-20	103.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158188_k127_398512_1	469383.Cwoe_0653	1.845e-111	376.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,2GK62@201174|Actinobacteria,4CR6R@84995|Rubrobacteria	84995|Rubrobacteria	OT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158188_k127_398512_4	323261.Noc_2767	2.351e-35	141.0	COG0346@1|root,COG0346@2|Bacteria,1RIUN@1224|Proteobacteria,1S8F7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	fosB2	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_398512_2	1297569.MESS2_1300041	1.683e-81	277.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,2TSPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158188_k127_398512_0	1278078.G419_15262	9.394e-195	629.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4FUE4@85025|Nocardiaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158188_k127_398512_6	469383.Cwoe_4556	2.372e-27	123.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158188_k127_398512_7	1108045.GORHZ_179_00120	2.926e-15	81.0	COG0406@1|root,COG1051@1|root,COG0406@2|Bacteria,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria,4GBRT@85026|Gordoniaceae	201174|Actinobacteria	FG	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158188_k127_398512_5	1122939.ATUD01000016_gene1833	3.235e-29	133.0	COG1051@1|root,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158188_k127_398512_3	1449976.KALB_3642	1.987e-54	208.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158188_k127_408701_2	1380390.JIAT01000011_gene2820	1.385e-44	167.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158188_k127_408701_1	656519.Halsa_1723	6.932e-47	180.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,25CN4@186801|Clostridia,3WB2H@53433|Halanaerobiales	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158188_k127_408701_0	42256.RradSPS_2243	8.927e-79	271.0	COG0813@1|root,COG0813@2|Bacteria,2GNT6@201174|Actinobacteria,4CU45@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158188_k127_408701_4	1122611.KB903987_gene3983	2.733e-31	136.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4EFMK@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158188_k127_408701_3	469383.Cwoe_1671	3.555e-37	151.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CQ9P@84995|Rubrobacteria	84995|Rubrobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR25158188_k127_409955_3	469383.Cwoe_1144	7.051e-23	99.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CSJJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158188_k127_409955_2	390989.JOEG01000025_gene95	5.201e-37	147.0	COG1357@1|root,COG1357@2|Bacteria,2I8N2@201174|Actinobacteria,4DCTJ@85008|Micromonosporales	201174|Actinobacteria	S	Pentapeptide repeat protein	mfpA	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158188_k127_409955_4	1283283.ATXA01000003_gene1645	0.0002764	51.0	2DW3A@1|root,33YCP@2|Bacteria,2GZ8M@201174|Actinobacteria,4EVKN@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158188_k127_409955_1	479434.Sthe_3345	3.488e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YF3@189775|Thermomicrobia	189775|Thermomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_409955_0	1341151.ASZU01000004_gene647	7.168e-86	287.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,27B5G@186824|Thermoactinomycetaceae	91061|Bacilli	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158188_k127_430754_2	1449355.JQNR01000003_gene286	2.297e-39	156.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria	201174|Actinobacteria	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158188_k127_430754_0	235985.BBPN01000040_gene354	6.883e-178	569.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158188_k127_430754_1	1101188.KI912155_gene1695	3.471e-48	195.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158188_k127_433010_8	1283299.AUKG01000001_gene3173	6.259e-19	88.0	2B6US@1|root,31NY4@2|Bacteria,2HRF0@201174|Actinobacteria,4CREA@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_433010_0	469383.Cwoe_5785	4.915e-128	433.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158188_k127_433010_7	1297570.MESS4_740027	1.914e-21	96.0	COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2TQN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158188_k127_433010_4	926569.ANT_11780	1.94e-44	182.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158188_k127_433010_2	555079.Toce_1469	5.067e-53	203.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia,42EME@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SRR25158188_k127_433010_1	797209.ZOD2009_03090	2.39e-86	296.0	COG0604@1|root,arCOG01458@2157|Archaea,2XU0Q@28890|Euryarchaeota,23SPC@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158188_k127_433010_5	1380390.JIAT01000011_gene2542	1.694e-39	160.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_433010_9	68170.KL590477_gene2551	1.995e-13	82.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4E7FF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_433010_3	1188256.BASI01000005_gene1609	9.388e-53	197.0	2AP53@1|root,31E6R@2|Bacteria,1Q6T5@1224|Proteobacteria,2TVR4@28211|Alphaproteobacteria,3FE4P@34008|Rhodovulum	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_433010_6	1172181.KB911708_gene8107	1.087e-38	154.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria	201174|Actinobacteria	P	nitric oxide dioxygenase activity	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158188_k127_440914_0	330084.JNYZ01000005_gene927	2.284e-113	380.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4E0AJ@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158188_k127_440914_2	1470593.BW43_00700	3.476e-60	219.0	COG1619@1|root,COG1619@2|Bacteria,1RDGY@1224|Proteobacteria,1T05T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	peptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158188_k127_440914_1	1122609.AUGT01000009_gene3335	7.236e-109	362.0	COG0123@1|root,COG0123@2|Bacteria,2I8UK@201174|Actinobacteria,4DU14@85009|Propionibacteriales	201174|Actinobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158188_k127_440914_3	1298863.AUEP01000008_gene1264	9.958e-33	132.0	COG3191@1|root,COG3191@2|Bacteria,2H89D@201174|Actinobacteria,4DRX9@85009|Propionibacteriales	201174|Actinobacteria	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158188_k127_457114_10	1449976.KALB_7073	7.494e-05	46.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4E06U@85010|Pseudonocardiales	201174|Actinobacteria	F	pfam nudix	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158188_k127_457114_2	469383.Cwoe_1859	5.772e-126	419.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4CPRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Glucose inhibited division protein A	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158188_k127_457114_9	391735.Veis_0027	4.046e-32	140.0	295PK@1|root,2ZT0Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_457114_3	479434.Sthe_0863	9.934e-121	406.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,27Z0R@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158188_k127_457114_5	1283299.AUKG01000002_gene3622	6.377e-112	377.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4CPYV@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158188_k127_457114_4	1380390.JIAT01000009_gene596	4.76e-119	400.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4CQAB@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158188_k127_457114_1	1380390.JIAT01000009_gene597	1.169e-183	593.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4CPFE@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158188_k127_457114_6	1380390.JIAT01000009_gene598	1.553e-55	207.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4CQBS@84995|Rubrobacteria	84995|Rubrobacteria	S	Basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158188_k127_457114_0	1380390.JIAT01000010_gene4818	7.832e-197	637.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158188_k127_457114_8	521098.Aaci_0840	2.23e-36	153.0	COG3885@1|root,COG3885@2|Bacteria,1TUKQ@1239|Firmicutes,4HJ5V@91061|Bacilli	91061|Bacilli	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
SRR25158188_k127_457114_7	405948.SACE_1231	3.834e-53	194.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4E1GE@85010|Pseudonocardiales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	ybeK	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158188_k127_457508_2	479433.Caci_7350	5.16e-61	220.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria	201174|Actinobacteria	G	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158188_k127_457508_0	105425.BBPL01000003_gene6812	1.878e-137	453.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,2NENA@228398|Streptacidiphilus	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_457508_1	105425.BBPL01000003_gene6811	4.68e-132	433.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,2NHBH@228398|Streptacidiphilus	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158188_k127_475556_0	1229780.BN381_430008	6.148e-141	461.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158188_k127_475556_1	1150399.AQYK01000001_gene2086	1.758e-46	180.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria,4FQNV@85023|Microbacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158188_k127_475556_3	768671.ThimaDRAFT_0325	7.555e-11	72.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1WYN6@135613|Chromatiales	135613|Chromatiales	K	SMART cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158188_k127_475556_2	43354.JOIJ01000026_gene3312	7.416e-44	166.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4E0W6@85010|Pseudonocardiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158188_k127_476330_0	266117.Rxyl_1165	5.511e-53	191.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158188_k127_487297_8	309801.trd_1240	5.953e-12	66.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,27XYD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158188_k127_487297_3	1283299.AUKG01000004_gene1239	1.736e-34	143.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4CQW7@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158188_k127_487297_5	35754.JNYJ01000061_gene2378	4.643e-24	117.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DAIV@85008|Micromonosporales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158188_k127_487297_6	191610.CATYP_08025	5.715e-21	105.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,22K21@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158188_k127_487297_9	1283299.AUKG01000004_gene1236	1.568e-09	70.0	COG0268@1|root,COG0268@2|Bacteria,2HRKP@201174|Actinobacteria,4CTNG@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S20	-	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158188_k127_487297_1	1380390.JIAT01000016_gene5645	1.094e-129	441.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158188_k127_487297_0	469383.Cwoe_2838	2.967e-262	822.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CP62@84995|Rubrobacteria	84995|Rubrobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158188_k127_487297_7	68199.JNZO01000022_gene4502	1.294e-19	91.0	COG3813@1|root,COG3813@2|Bacteria,2GRIY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
SRR25158188_k127_487297_4	1210884.HG799463_gene9985	5.257e-31	129.0	COG0635@1|root,COG0635@2|Bacteria,2IWR5@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158188_k127_50418_6	266117.Rxyl_2444	9.976e-43	173.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158188_k127_50418_7	234267.Acid_6517	5.451e-28	122.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria	57723|Acidobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_50418_2	882086.SacxiDRAFT_4082	7.569e-121	398.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria,4DZ90@85010|Pseudonocardiales	201174|Actinobacteria	Q	Fumarylacetoacetase	FAH	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158188_k127_50418_3	1278307.KB907020_gene889	2.967e-103	358.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_9
SRR25158188_k127_50418_5	1183438.GKIL_2106	2.847e-49	191.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SRR25158188_k127_50418_1	105425.BBPL01000022_gene974	1.045e-154	533.0	COG1404@1|root,COG1404@2|Bacteria,2GKJR@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
SRR25158188_k127_50418_0	68194.JNXR01000016_gene7310	5.563e-270	841.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158188_k127_50418_4	1380390.JIAT01000010_gene4131	7.773e-73	260.0	COG0477@1|root,COG2814@2|Bacteria,2HQMP@201174|Actinobacteria,4CS79@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_530680_0	1380390.JIAT01000013_gene145	9.444e-149	495.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158188_k127_530680_1	388413.ALPR1_05140	2.428e-72	257.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158188_k127_530680_2	1120966.AUBU01000014_gene596	5.836e-18	88.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
SRR25158188_k127_530680_3	1380390.JIAT01000013_gene145	0.0002198	49.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158188_k127_538946_3	1157943.KB892705_gene3895	4.596e-08	56.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,233H1@1762|Mycobacteriaceae	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158188_k127_538946_1	469383.Cwoe_1687	2.065e-63	223.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CPVJ@84995|Rubrobacteria	84995|Rubrobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158188_k127_538946_0	1380390.JIAT01000011_gene2865	7.857e-116	387.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4CPEN@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA integrity scanning protein DisA	-	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH_2
SRR25158188_k127_538946_2	469383.Cwoe_1685	4.576e-28	117.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CP8Q@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
SRR25158188_k127_543567_1	937777.Deipe_0187	3.314e-120	392.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158188_k127_543567_8	1089553.Tph_c16130	1.583e-32	145.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158188_k127_543567_3	469383.Cwoe_3087	1.597e-88	304.0	COG2195@1|root,COG2195@2|Bacteria,2HPTW@201174|Actinobacteria,4CR7V@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158188_k127_543567_0	1121430.JMLG01000002_gene1257	2.949e-227	715.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,260W1@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
SRR25158188_k127_543567_9	1122998.AUHZ01000020_gene1708	0.0008026	49.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158188_k127_543567_2	1122939.ATUD01000005_gene2648	4.139e-90	319.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CPSV@84995|Rubrobacteria	84995|Rubrobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158188_k127_543567_5	1283299.AUKG01000002_gene5315	3.532e-46	177.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158188_k127_543567_4	926550.CLDAP_02240	2.328e-70	249.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158188_k127_543567_7	66874.JOFS01000006_gene4336	1.013e-40	161.0	COG1708@1|root,COG1708@2|Bacteria,2I1CC@201174|Actinobacteria	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158188_k127_543567_6	1283299.AUKG01000002_gene5321	7.175e-46	173.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158188_k127_573048_15	469383.Cwoe_5392	1.063e-11	75.0	COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_573048_4	1380390.JIAT01000010_gene4351	3.318e-65	252.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRR25158188_k127_573048_8	525904.Tter_2070	7.223e-36	143.0	COG0586@1|root,COG0586@2|Bacteria,2NQ0I@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR25158188_k127_573048_1	1283299.AUKG01000002_gene4576	2.579e-127	416.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CPAE@84995|Rubrobacteria	84995|Rubrobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158188_k127_573048_12	485918.Cpin_6490	3.711e-27	119.0	COG3288@1|root,COG3288@2|Bacteria,4NT78@976|Bacteroidetes,1ITS9@117747|Sphingobacteriia	976|Bacteroidetes	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158188_k127_573048_0	1283299.AUKG01000002_gene4578	2.151e-147	487.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CPKR@84995|Rubrobacteria	84995|Rubrobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158188_k127_573048_10	1123023.JIAI01000003_gene3072	1.422e-31	142.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158188_k127_573048_5	555088.DealDRAFT_2393	8.053e-62	230.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,42JU0@68298|Syntrophomonadaceae	186801|Clostridia	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158188_k127_573048_2	1382356.JQMP01000001_gene1035	1.126e-125	418.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158188_k127_573048_13	1122939.ATUD01000001_gene585	1.016e-23	106.0	COG3837@1|root,COG3837@2|Bacteria,2HR5Z@201174|Actinobacteria,4CT1K@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_573048_9	469383.Cwoe_3626	3.617e-35	140.0	COG3837@1|root,COG3837@2|Bacteria,2HR5Z@201174|Actinobacteria,4CT1K@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_573048_3	370438.PTH_1123	1.163e-108	364.0	COG0863@1|root,COG0863@2|Bacteria,1UZ5E@1239|Firmicutes,24F8E@186801|Clostridia	186801|Clostridia	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158188_k127_573048_14	1089551.KE386572_gene1469	1.341e-13	79.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,4BQT4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Uncharacterised protein family UPF0102	MA20_24645	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158188_k127_573048_6	1283299.AUKG01000002_gene4754	5.379e-57	206.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CQ01@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158188_k127_573048_7	1283299.AUKG01000002_gene4752	8.067e-53	194.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CQ3H@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158188_k127_573048_11	1121468.AUBR01000050_gene2015	2.07e-29	130.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158188_k127_573048_16	1536770.R50345_18995	1.97e-10	61.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158188_k127_60108_4	1380390.JIAT01000014_gene6206	5.291e-43	175.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CPD7@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158188_k127_60108_1	1283299.AUKG01000001_gene3087	7.547e-108	384.0	COG3857@1|root,COG3857@2|Bacteria,2HNUC@201174|Actinobacteria,4CQ2I@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158188_k127_60108_2	1502852.FG94_01154	4.204e-71	258.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,475FS@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158188_k127_60108_0	562970.Btus_2543	7.446e-159	508.0	COG0473@1|root,COG0473@2|Bacteria,1UJAS@1239|Firmicutes,4HCZN@91061|Bacilli,2787J@186823|Alicyclobacillaceae	91061|Bacilli	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
SRR25158188_k127_60108_3	246194.CHY_1969	4.72e-44	167.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42GDE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,PAS_9,PocR
SRR25158188_k127_61597_0	525904.Tter_0058	9.329e-159	512.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158188_k127_61597_3	667014.Thein_0523	6.974e-21	96.0	COG0721@1|root,COG0721@2|Bacteria,2GI03@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158188_k127_61597_2	293826.Amet_1627	1.955e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,36MMP@31979|Clostridiaceae	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158188_k127_61597_1	1218075.BAYA01000001_gene363	3.589e-91	308.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,1JZNK@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158188_k127_61597_4	42345.XP_008799136.1	5.216e-05	52.0	COG1257@1|root,KOG2480@2759|Eukaryota,37MBQ@33090|Viridiplantae,3G7H8@35493|Streptophyta,3KS5Q@4447|Liliopsida	35493|Streptophyta	I	A reductase	HMG2	GO:0003674,GO:0003824,GO:0004420,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005777,GO:0005778,GO:0005783,GO:0005789,GO:0006629,GO:0006694,GO:0006720,GO:0006721,GO:0006722,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0009058,GO:0009526,GO:0009536,GO:0009987,GO:0012505,GO:0016020,GO:0016104,GO:0016114,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0031090,GO:0031903,GO:0031966,GO:0031967,GO:0031975,GO:0031984,GO:0042170,GO:0042175,GO:0042282,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044435,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0055114,GO:0071704,GO:0098588,GO:0098805,GO:0098827,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
SRR25158188_k127_647305_2	1121472.AQWN01000005_gene2382	1.647e-71	261.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,260BC@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_4
SRR25158188_k127_647305_5	253839.SSNG_00411	1.936e-32	130.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158188_k127_647305_0	469383.Cwoe_5528	5.462e-240	756.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158188_k127_647305_1	1120983.KB894570_gene1248	1.529e-88	311.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TWH9@28211|Alphaproteobacteria,1JPSN@119043|Rhodobiaceae	28211|Alphaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158188_k127_647305_3	287986.DV20_33355	1.788e-69	246.0	COG0626@1|root,COG0626@2|Bacteria,2GMD8@201174|Actinobacteria,4DY14@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158188_k127_647305_7	1232683.ADIMK_0007	4.053e-16	93.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,467K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158188_k127_647305_4	717605.Theco_2820	1.245e-39	151.0	COG2315@1|root,COG2315@2|Bacteria,1VYE4@1239|Firmicutes,4HXF5@91061|Bacilli	91061|Bacilli	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158188_k127_647305_6	469383.Cwoe_1693	1.573e-27	114.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_656723_2	929712.KI912613_gene2019	2.499e-36	156.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	fdnI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158188_k127_656723_1	929712.KI912613_gene2018	5.883e-74	255.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria	201174|Actinobacteria	M	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158188_k127_656723_0	42256.RradSPS_2748	3.153e-98	325.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CPC2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158188_k127_663099_2	316274.Haur_1203	3.536e-75	261.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158188_k127_663099_0	1040983.AXAE01000011_gene3080	1.814e-109	361.0	COG0596@1|root,COG0596@2|Bacteria,1QU30@1224|Proteobacteria,2TSNY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the peptidase S33 family	pip2	-	3.5.1.101	ko:K18457	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158188_k127_663099_3	1121468.AUBR01000050_gene2015	7.61e-29	124.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158188_k127_663099_1	997346.HMPREF9374_0831	2.459e-88	301.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,27CSU@186824|Thermoactinomycetaceae	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158188_k127_694673_2	1400520.LFAB_03260	2.686e-23	99.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158188_k127_694673_6	1122994.AUFR01000031_gene605	0.0008576	48.0	COG3402@1|root,COG3402@2|Bacteria,2I2JX@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158188_k127_694673_1	1128421.JAGA01000002_gene1281	2.44e-26	121.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158188_k127_694673_0	1187851.A33M_2641	8.299e-33	137.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2VC8E@28211|Alphaproteobacteria,3FEC9@34008|Rhodovulum	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158188_k127_694673_3	1380390.JIAT01000009_gene1954	1.314e-16	82.0	2A6PH@1|root,30VHE@2|Bacteria,2HRXZ@201174|Actinobacteria,4CU19@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_694673_5	1380390.JIAT01000009_gene1954	1.584e-07	60.0	2A6PH@1|root,30VHE@2|Bacteria,2HRXZ@201174|Actinobacteria,4CU19@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_694673_4	469383.Cwoe_0969	2.596e-08	62.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	LTD,PhoD,PhoD_N,SdiA-regulated,VPEP
SRR25158188_k127_699992_4	1163408.UU9_08852	5.101e-78	277.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X3IK@135614|Xanthomonadales	135614|Xanthomonadales	CQ	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrome_CBB3
SRR25158188_k127_699992_2	436114.SYO3AOP1_0794	5.687e-100	340.0	COG2171@1|root,COG2171@2|Bacteria,2G3KV@200783|Aquificae	200783|Aquificae	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158188_k127_699992_1	1380390.JIAT01000010_gene4797	2.031e-120	396.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158188_k127_699992_3	1380390.JIAT01000010_gene4796	3.874e-82	292.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CP61@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158188_k127_699992_0	469383.Cwoe_3259	9.891e-136	460.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CPXQ@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158188_k127_699992_6	929712.KI912613_gene3614	7.824e-45	183.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158188_k127_699992_8	526218.Sterm_1184	1.036e-11	76.0	COG1051@1|root,COG1051@2|Bacteria,37ASE@32066|Fusobacteria	32066|Fusobacteria	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158188_k127_699992_7	743525.TSC_c04750	4.517e-27	128.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1WKRH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	COGs COG3593 ATP-dependent endonuclease of the OLD family	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
SRR25158188_k127_699992_5	469383.Cwoe_3272	4.55e-67	235.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CPRV@84995|Rubrobacteria	84995|Rubrobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158188_k127_723926_0	330084.JNYZ01000015_gene6047	2.824e-124	407.0	COG1529@1|root,COG1529@2|Bacteria,2I8D1@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde oxidase xanthine dehydrogenase, a b hammerhead	-	-	1.3.99.8	ko:K16877	ko00365,ko01120,map00365,map01120	-	R02987	RC01856	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158188_k127_723926_9	1408418.JNJH01000011_gene3636	2.524e-08	66.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,2JSQF@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158188_k127_723926_2	246196.MSMEI_2056	1.153e-67	249.0	COG2141@1|root,COG2141@2|Bacteria,2GJ04@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158188_k127_723926_8	479431.Namu_4940	3.714e-15	80.0	COG0607@1|root,COG0607@2|Bacteria,2IKTC@201174|Actinobacteria,4ET2W@85013|Frankiales	201174|Actinobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158188_k127_723926_3	246196.MSMEI_2053	4.647e-52	210.0	COG0624@1|root,COG0624@2|Bacteria,2I9Y6@201174|Actinobacteria,23ER8@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158188_k127_723926_7	471853.Bcav_3453	1.644e-30	125.0	2EI6P@1|root,33BY0@2|Bacteria,2H6KP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_723926_1	285535.JOEY01000003_gene10500	4.894e-122	403.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158188_k127_723926_4	479434.Sthe_2391	1.807e-40	156.0	COG3467@1|root,COG3467@2|Bacteria,2G94U@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158188_k127_723926_5	1200792.AKYF01000009_gene3195	1.032e-38	160.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,26QQG@186822|Paenibacillaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158188_k127_723926_6	436308.Nmar_1070	6.808e-32	130.0	COG0119@1|root,arCOG02092@2157|Archaea,41SBX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158188_k127_735065_0	880073.Calab_1841	1.649e-84	293.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158188_k127_735065_1	44056.XP_009037550.1	1.01e-57	219.0	COG4992@1|root,KOG1401@2759|Eukaryota	2759|Eukaryota	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3,PRK
SRR25158188_k127_735065_3	999541.bgla_2g04880	9.385e-17	89.0	COG0500@1|root,COG2226@2|Bacteria,1QTSY@1224|Proteobacteria,2VWQB@28216|Betaproteobacteria,1K6XB@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158188_k127_735065_2	1120973.AQXL01000129_gene2446	1.811e-40	153.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,27AT7@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158188_k127_772086_8	926560.KE387023_gene2382	7.957e-18	85.0	COG0604@1|root,COG0604@2|Bacteria,1WM0U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158188_k127_772086_3	1133849.O3I_037875	1.261e-52	192.0	COG1309@1|root,COG1309@2|Bacteria,2HH54@201174|Actinobacteria,4G3S3@85025|Nocardiaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158188_k127_772086_5	1283299.AUKG01000001_gene3197	1.667e-39	159.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158188_k127_772086_2	469383.Cwoe_1881	1.642e-64	225.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158188_k127_772086_7	452863.Achl_3197	2.404e-20	97.0	COG1573@1|root,COG1573@2|Bacteria,2GRPK@201174|Actinobacteria	201174|Actinobacteria	L	uracil-dna glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158188_k127_772086_0	1122182.KB903833_gene5401	1.455e-120	428.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158188_k127_772086_4	211114.JOEF01000043_gene6101	4.629e-46	173.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4E2QV@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158188_k127_772086_6	1392488.JHZY01000002_gene552	2.068e-21	102.0	2DRSE@1|root,33CV2@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4304)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4304
SRR25158188_k127_772086_1	264732.Moth_2105	2.332e-92	305.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,42EXT@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158188_k127_808606_2	1380390.JIAT01000015_gene5734	2.275e-20	99.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Laminin_G_3,Phosphoesterase
SRR25158188_k127_808606_1	67315.JOBD01000018_gene7295	7.478e-27	116.0	2AYDD@1|root,31QGA@2|Bacteria,2IS2F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158188_k127_808606_0	1122611.KB903996_gene7457	4.846e-219	685.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4ENHD@85012|Streptosporangiales	201174|Actinobacteria	E	GMC oxidoreductase	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158188_k127_809096_0	1380390.JIAT01000001_gene5111	7.461e-89	317.0	COG1164@1|root,COG1164@2|Bacteria,2IGPX@201174|Actinobacteria,4CPUP@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158188_k127_809096_2	1382306.JNIM01000001_gene4040	6.16e-22	108.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158188_k127_809096_1	431943.CKL_3785	3.126e-26	122.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,36FW2@31979|Clostridiaceae	186801|Clostridia	M	NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
SRR25158188_k127_809096_4	1157637.KB892122_gene458	2.671e-15	83.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158188_k127_809096_3	1283299.AUKG01000003_gene542	3.35e-16	82.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4CPRF@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158188_k127_809870_4	649831.L083_4054	1.654e-10	67.0	2FF2Y@1|root,34717@2|Bacteria,2GTPB@201174|Actinobacteria,4DFKD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_809870_1	1382306.JNIM01000001_gene2629	3.884e-183	583.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158188_k127_809870_2	2074.JNYD01000013_gene6814	1.861e-44	169.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158188_k127_809870_3	110319.CF8_3624	3.766e-19	100.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4DQMV@85009|Propionibacteriales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158188_k127_809870_0	1120949.KB903294_gene4103	2.966e-213	674.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4DDNS@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_814370_1	471853.Bcav_3012	4.134e-66	237.0	COG1073@1|root,COG1073@2|Bacteria,2IA0F@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158188_k127_814370_3	1380356.JNIK01000015_gene2514	2.066e-36	149.0	COG3103@1|root,COG5479@1|root,COG4991@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4EX5K@85013|Frankiales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SRR25158188_k127_814370_0	861299.J421_0831	4.977e-87	301.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158188_k127_814370_2	467200.ACFA01000913_gene3395	5.489e-56	204.0	COG1804@1|root,COG1804@2|Bacteria,2GMW8@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158188_k127_81775_0	1128421.JAGA01000002_gene261	1.709e-49	186.0	COG1319@1|root,COG1319@2|Bacteria,2NQUQ@2323|unclassified Bacteria	2|Bacteria	C	CO dehydrogenase flavoprotein C-terminal domain	yagS	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158188_k127_81775_3	1380390.JIAT01000017_gene5363	1.231e-19	102.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4CQMI@84995|Rubrobacteria	84995|Rubrobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158188_k127_81775_1	1033730.CAHG01000012_gene2301	1.35e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DMYC@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158188_k127_81775_4	1224746.B932_0761	1.32e-05	49.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria	1224|Proteobacteria	P	heavy metal transport detoxification protein	merP	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR25158188_k127_81775_2	1569209.BBPH01000129_gene650	1.369e-35	149.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,2PV8I@265|Paracoccus	28211|Alphaproteobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158188_k127_823555_2	1122613.ATUP01000001_gene1897	3.765e-07	61.0	COG3396@1|root,COG3396@2|Bacteria,1QYPN@1224|Proteobacteria,2TXUS@28211|Alphaproteobacteria,44152@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Long-chain fatty aldehyde decarbonylase	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158188_k127_823555_1	661478.OP10G_0321	8.413e-47	175.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ykkB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158188_k127_823555_0	1051632.TPY_0167	2.706e-96	324.0	COG1257@1|root,COG1257@2|Bacteria,1VWYW@1239|Firmicutes	1239|Firmicutes	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
SRR25158188_k127_856299_3	469383.Cwoe_0746	1.144e-49	194.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CPUE@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158188_k127_856299_2	765420.OSCT_2090	8.059e-96	327.0	COG1071@1|root,COG1071@2|Bacteria,2G6HY@200795|Chloroflexi,3754C@32061|Chloroflexia	32061|Chloroflexia	C	PFAM dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158188_k127_856299_0	656024.FsymDg_4011	5.385e-125	416.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4ESZR@85013|Frankiales	201174|Actinobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158188_k127_856299_8	931627.MycrhDRAFT_0324	7.904e-23	109.0	COG0627@1|root,COG0627@2|Bacteria,2GKNS@201174|Actinobacteria,232HG@1762|Mycobacteriaceae	201174|Actinobacteria	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158188_k127_856299_9	535289.Dtpsy_3145	3.865e-05	49.0	COG3064@1|root,COG3064@2|Bacteria,1R56Q@1224|Proteobacteria,2VHQR@28216|Betaproteobacteria,4AARQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_856299_5	1283299.AUKG01000001_gene2455	8.855e-34	140.0	2ASH4@1|root,31HXG@2|Bacteria,2HMFJ@201174|Actinobacteria,4CQBD@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_856299_4	929712.KI912613_gene970	2.121e-40	155.0	COG2411@1|root,COG2411@2|Bacteria,2HNQQ@201174|Actinobacteria,4CPX9@84995|Rubrobacteria	84995|Rubrobacteria	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158188_k127_856299_1	1380390.JIAT01000010_gene4553	5.288e-105	359.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4CPB1@84995|Rubrobacteria	84995|Rubrobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158188_k127_856299_6	1242864.D187_001773	1.814e-33	134.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158188_k127_856299_7	1235279.C772_02619	5.802e-32	128.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,26FQN@186818|Planococcaceae	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158188_k127_860842_5	1449346.JQMO01000003_gene2191	1.082e-11	68.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_860842_1	1306990.BARG01000036_gene4276	8.455e-64	225.0	COG2085@1|root,COG2085@2|Bacteria,2GP3E@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158188_k127_860842_0	479434.Sthe_2024	4.034e-164	528.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158188_k127_860842_2	446470.Snas_5888	2.49e-49	198.0	KOG2391@1|root,3279X@2|Bacteria,2I3V8@201174|Actinobacteria,4EYRC@85014|Glycomycetales	201174|Actinobacteria	O	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_860842_4	1183438.GKIL_2197	2.476e-16	81.0	COG5007@1|root,COG5007@2|Bacteria,1GRBE@1117|Cyanobacteria	1117|Cyanobacteria	K	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
SRR25158188_k127_860842_3	469383.Cwoe_1610	1.526e-17	93.0	COG0278@1|root,COG0278@2|Bacteria,2HR8V@201174|Actinobacteria,4CT56@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRR25158188_k127_873556_10	1196323.ALKF01000183_gene5351	7.025e-21	100.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158188_k127_873556_4	1463841.JOIR01000028_gene395	1.023e-37	164.0	COG2208@1|root,COG3829@1|root,COG2208@2|Bacteria,COG3829@2|Bacteria,2IA25@201174|Actinobacteria	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,PAS,PAS_4,PAS_8,PAS_9,SpoIIE
SRR25158188_k127_873556_8	1121918.ARWE01000001_gene620	1.982e-24	115.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,42S95@68525|delta/epsilon subdivisions,2WNPS@28221|Deltaproteobacteria,43SFI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
SRR25158188_k127_873556_9	268407.PWYN_25260	3.824e-23	108.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HI6P@91061|Bacilli,26SZE@186822|Paenibacillaceae	91061|Bacilli	CO	Alkyl hydroperoxide reductase	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158188_k127_873556_7	937777.Deipe_0801	6.336e-27	123.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158188_k127_873556_11	469383.Cwoe_4516	3.185e-16	87.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CT29@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158188_k127_873556_5	1380390.JIAT01000015_gene5703	6.108e-36	152.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CQ2F@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158188_k127_873556_12	710696.Intca_2705	7.124e-11	66.0	COG1547@1|root,COG1547@2|Bacteria,2IHUS@201174|Actinobacteria,4FH6W@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158188_k127_873556_6	1401064.HMPREF2129_02205	1.31e-28	117.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,22N7C@1653|Corynebacteriaceae	201174|Actinobacteria	C	ferredoxin	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158188_k127_873556_2	266117.Rxyl_1348	7.22e-45	180.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158188_k127_873556_1	266117.Rxyl_1349	8.548e-61	222.0	COG1053@1|root,COG1053@2|Bacteria,2ICBE@201174|Actinobacteria,4CSY4@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
SRR25158188_k127_873556_13	357808.RoseRS_3762	2.019e-10	73.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi,3752U@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158188_k127_873556_3	66373.JOFQ01000018_gene1151	4.671e-44	175.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158188_k127_873556_0	65497.JODV01000014_gene3315	1.734e-74	261.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4DXBF@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158188_k127_888336_0	1283299.AUKG01000003_gene500	6.188e-113	384.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158188_k127_888336_2	118005.AWNK01000007_gene706	1.431e-18	91.0	COG0718@1|root,COG0718@2|Bacteria	2|Bacteria	S	YbaB/EbfC DNA-binding family	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158188_k127_888336_1	266117.Rxyl_0510	1.324e-44	164.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158188_k127_901761_3	266117.Rxyl_0772	4.637e-48	174.0	COG2129@1|root,COG2129@2|Bacteria,2IJW1@201174|Actinobacteria,4CQ37@84995|Rubrobacteria	84995|Rubrobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_901761_0	266117.Rxyl_0773	1.066e-210	667.0	COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158188_k127_901761_1	1122611.KB904029_gene5414	2.764e-161	545.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4EFY3@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158188_k127_901761_2	1283299.AUKG01000002_gene4310	1.9e-103	341.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4CPSG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158188_k127_911682_4	760568.Desku_1548	5.684e-11	74.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia,2609W@186807|Peptococcaceae	186801|Clostridia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158188_k127_911682_2	1121439.dsat_1072	5.479e-40	160.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,2M954@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158188_k127_911682_0	292459.STH817	6.147e-115	381.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158188_k127_911682_1	469383.Cwoe_5924	9.221e-60	221.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158188_k127_911682_3	469383.Cwoe_5925	1.076e-23	102.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158188_k127_912569_6	263358.VAB18032_07050	9.063e-33	139.0	COG1960@1|root,COG1960@2|Bacteria,2IJ5B@201174|Actinobacteria,4DDBY@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
SRR25158188_k127_912569_1	1121272.KB903249_gene1730	1.329e-125	412.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4D8GI@85008|Micromonosporales	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_912569_2	1033734.CAET01000016_gene4097	1.747e-100	347.0	COG3340@1|root,COG3340@2|Bacteria,1UYTJ@1239|Firmicutes,4HFAT@91061|Bacilli,1ZD52@1386|Bacillus	91061|Bacilli	E	Peptidase family S51	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158188_k127_912569_4	1385521.N803_04745	9.005e-56	208.0	COG0697@1|root,COG0697@2|Bacteria,2I9T9@201174|Actinobacteria,4FFPR@85021|Intrasporangiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158188_k127_912569_5	235985.BBPN01000033_gene91	1.994e-34	149.0	COG1520@1|root,COG4934@1|root,COG1520@2|Bacteria,COG4934@2|Bacteria,2IAHP@201174|Actinobacteria	201174|Actinobacteria	O	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FG-GAP,VCBS
SRR25158188_k127_912569_3	997346.HMPREF9374_0374	2.893e-88	306.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,27BFR@186824|Thermoactinomycetaceae	91061|Bacilli	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158188_k127_912569_0	1380390.JIAT01000016_gene5650	2.719e-243	769.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158188_k127_912569_7	710111.FraQA3DRAFT_0543	0.0002356	43.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4ES6C@85013|Frankiales	201174|Actinobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158188_k127_927829_2	1463901.JOIY01000013_gene6029	2.02e-75	266.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158188_k127_927829_0	469383.Cwoe_0936	2.332e-100	340.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CSW8@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158188_k127_927829_1	525904.Tter_0881	3.671e-82	281.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158188_k127_940091_4	1329516.JPST01000030_gene2903	3.489e-37	149.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,27BD9@186824|Thermoactinomycetaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158188_k127_940091_2	1380394.JADL01000004_gene6007	1.382e-138	446.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,2JQGU@204441|Rhodospirillales	204441|Rhodospirillales	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158188_k127_940091_1	1380394.JADL01000004_gene6008	1.629e-166	541.0	COG0824@1|root,COG1250@1|root,COG0824@2|Bacteria,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,2JQTT@204441|Rhodospirillales	204441|Rhodospirillales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,4HBT_2
SRR25158188_k127_940091_0	235985.BBPN01000005_gene2851	8.299e-183	597.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,2NHDP@228398|Streptacidiphilus	201174|Actinobacteria	C	ATP-grasp domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158188_k127_940091_3	1380391.JIAS01000013_gene3519	6.162e-69	240.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JQQC@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158188_k127_960140_1	67356.KL575607_gene9041	1.006e-73	258.0	COG0451@1|root,COG0451@2|Bacteria,2GJYY@201174|Actinobacteria	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158188_k127_960140_0	234267.Acid_2875	9.509e-113	381.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158188_k127_960140_4	743719.PaelaDRAFT_3720	1.154e-10	74.0	COG1572@1|root,COG1572@2|Bacteria,1U2J3@1239|Firmicutes,4IC6K@91061|Bacilli,27274@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
SRR25158188_k127_960140_3	575540.Isop_0030	6.317e-11	70.0	COG1595@1|root,COG1595@2|Bacteria,2J0H3@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158188_k127_960140_2	68219.JNXI01000017_gene7338	3.216e-16	82.0	2DCTV@1|root,2ZFB5@2|Bacteria,2GMNC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_961428_3	926560.KE387023_gene1448	6.595e-09	69.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1WM5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
SRR25158188_k127_961428_1	994479.GL877879_gene5895	1.528e-115	387.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DZDW@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158188_k127_961428_0	479434.Sthe_0337	2.12e-276	883.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158188_k127_961428_2	1120983.KB894574_gene1087	7.349e-25	106.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,1JP8P@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158188_k127_966545_0	1128421.JAGA01000001_gene2422	1.923e-45	169.0	COG1522@1|root,COG2146@1|root,COG3253@1|root,COG1522@2|Bacteria,COG2146@2|Bacteria,COG3253@2|Bacteria,2NQGU@2323|unclassified Bacteria	2|Bacteria	K	AsnC-type helix-turn-helix domain	MA20_05845	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Chlor_dismutase,HTH_AsnC-type,Rieske
SRR25158188_k127_966545_1	946483.Cenrod_0250	1.465e-35	152.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158188_k127_969279_0	926560.KE387027_gene713	2.66e-163	535.0	COG2303@1|root,COG2303@2|Bacteria,1WMTM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158188_k127_969279_2	1283299.AUKG01000002_gene3909	2.421e-28	124.0	COG3336@1|root,COG3336@2|Bacteria,2GSID@201174|Actinobacteria,4CRYT@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158188_k127_969279_1	1123504.JQKD01000002_gene3972	3.83e-38	147.0	COG2323@1|root,COG2323@2|Bacteria,1RATW@1224|Proteobacteria,2VQMU@28216|Betaproteobacteria,4ADSQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158188_k127_969279_3	1380390.JIAT01000013_gene83	2.132e-25	112.0	2A3C5@1|root,30RUG@2|Bacteria,2HQZV@201174|Actinobacteria,4CSTF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_970257_10	469383.Cwoe_1819	1.022e-12	80.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158188_k127_970257_11	1120948.KB903224_gene366	5.574e-11	72.0	2AVNR@1|root,31MFR@2|Bacteria,2HBMC@201174|Actinobacteria	1120948.KB903224_gene366|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_970257_8	469383.Cwoe_0760	1.576e-24	114.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158188_k127_970257_0	1157634.KB912988_gene4521	2.508e-223	701.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158188_k127_970257_4	1429046.RR21198_1984	8.411e-151	488.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4G023@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158188_k127_970257_12	469383.Cwoe_1530	1.062e-09	68.0	COG1280@1|root,COG1280@2|Bacteria,2HRC6@201174|Actinobacteria	201174|Actinobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158188_k127_970257_9	298655.KI912266_gene3221	1.135e-22	106.0	COG2093@1|root,COG2093@2|Bacteria	2|Bacteria	K	Spt4/RpoE2 zinc finger	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	DZR,Ion_trans,Ion_trans_2,PP2C_2
SRR25158188_k127_970257_1	1172179.AUKV01000016_gene2208	2.933e-210	666.0	COG0477@1|root,COG2814@2|Bacteria,2I7MG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_970257_2	1380370.JIBA01000013_gene1327	5.254e-179	572.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4FG51@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158188_k127_970257_7	1380390.JIAT01000011_gene2324	2.069e-85	296.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4CTG0@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158188_k127_970257_14	1121406.JAEX01000012_gene659	0.0006514	49.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria,2M8PP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS,PAS_4,PAS_9,dCache_1
SRR25158188_k127_970257_13	1003195.SCAT_2275	7.5e-09	64.0	COG2197@1|root,COG2197@2|Bacteria,2GQH1@201174|Actinobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158188_k127_970257_5	1380390.JIAT01000013_gene160	7.827e-113	374.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4CTID@84995|Rubrobacteria	84995|Rubrobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtC	-	-	-	-	-	-	-	-	-	-	-	GATase_4
SRR25158188_k127_970257_3	1283299.AUKG01000001_gene3510	1.633e-152	495.0	COG0531@1|root,COG0531@2|Bacteria,2IDWU@201174|Actinobacteria	201174|Actinobacteria	E	Amino acid permease	potE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158188_k127_970257_6	981369.JQMJ01000004_gene2819	2.637e-92	310.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,2NFNP@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_972288_5	383372.Rcas_1160	1.654e-91	303.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158188_k127_972288_9	1035191.HMPREF0185_01934	8.293e-11	72.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158188_k127_972288_3	469383.Cwoe_0789	3.856e-100	347.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158188_k127_972288_10	426117.M446_1570	3.742e-08	61.0	COG1670@1|root,COG1670@2|Bacteria,1RF8W@1224|Proteobacteria,2U707@28211|Alphaproteobacteria,1JVHX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158188_k127_972288_7	1380390.JIAT01000009_gene1527	1.849e-58	213.0	COG1573@1|root,COG1573@2|Bacteria,2HNTA@201174|Actinobacteria,4CQ1J@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158188_k127_972288_1	469383.Cwoe_0782	8.528e-127	425.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CRR6@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158188_k127_972288_8	1123371.ATXH01000015_gene1652	7.075e-27	114.0	COG0432@1|root,COG0432@2|Bacteria,2GHVM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158188_k127_972288_4	1041930.Mtc_1965	1.541e-91	323.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
SRR25158188_k127_972288_11	1121091.AUMP01000006_gene4105	4.156e-05	46.0	2DTBP@1|root,33JKJ@2|Bacteria,1VKDH@1239|Firmicutes,4I0AV@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_972288_0	1283299.AUKG01000004_gene1030	1.256e-208	674.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_972288_2	479434.Sthe_1187	9.754e-114	393.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,27Z0P@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158188_k127_972288_6	477974.Daud_0538	1.918e-77	291.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DC@186807|Peptococcaceae	186801|Clostridia	T	Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,PAS,PocR,SBP_bac_3
SRR25158188_k127_979756_1	1122939.ATUD01000005_gene2585	1.643e-55	202.0	2DKYI@1|root,30WMB@2|Bacteria,2I81T@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRR25158188_k127_979756_3	1283299.AUKG01000001_gene2158	1.594e-09	65.0	2B8TX@1|root,32240@2|Bacteria,2HRST@201174|Actinobacteria,4CTW1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_979756_0	525909.Afer_0855	1.431e-88	311.0	COG1376@1|root,COG1376@2|Bacteria,2GWPY@201174|Actinobacteria,4CNN9@84992|Acidimicrobiia	84992|Acidimicrobiia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158188_k127_979756_2	1123248.KB893386_gene1929	1.949e-20	100.0	COG3467@1|root,COG3467@2|Bacteria,4NQFR@976|Bacteroidetes,1ITPB@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158188_k127_982717_2	1380390.JIAT01000009_gene1592	4.957e-68	254.0	COG2199@1|root,COG5000@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,2IA4H@201174|Actinobacteria,4CP5Q@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
SRR25158188_k127_982717_0	309801.trd_0562	9.455e-279	885.0	COG0567@1|root,COG0567@2|Bacteria,2G638@200795|Chloroflexi,27XYT@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158188_k127_982717_1	1380390.JIAT01000010_gene4759	2.271e-100	338.0	COG0568@1|root,COG0568@2|Bacteria,2HGMA@201174|Actinobacteria,4CR9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 factor, region 1.2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158188_k127_98631_3	266117.Rxyl_0771	4.023e-54	216.0	arCOG06048@1|root,31EJQ@2|Bacteria,2GPSC@201174|Actinobacteria,4CQDB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_98631_1	1121428.DESHY_40191___1	3.146e-207	658.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,2601Q@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158188_k127_98631_4	68194.JNXR01000010_gene5401	1.286e-53	195.0	COG1802@1|root,COG1802@2|Bacteria,2HS3R@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158188_k127_98631_0	321955.AAGP01000017_gene2194	0.0	1113.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4FAN4@85019|Brevibacteriaceae	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158188_k127_98631_2	1448860.BBJO01000014_gene1236	1.433e-74	258.0	COG2086@1|root,arCOG00446@2157|Archaea,2XW02@28890|Euryarchaeota,23TZ0@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein, beta subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158188_k127_98631_5	634497.HAH_5184	4.404e-18	90.0	COG2025@1|root,arCOG00447@2157|Archaea,2XUIS@28890|Euryarchaeota,23T9A@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158188_k127_987109_11	1382306.JNIM01000001_gene2893	7.223e-12	70.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158188_k127_987109_8	1382304.JNIL01000001_gene1297	2.426e-46	180.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158188_k127_987109_10	604331.AUHY01000041_gene506	3.141e-27	125.0	COG0601@1|root,COG0601@2|Bacteria,1WMC0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158188_k127_987109_5	1123023.JIAI01000001_gene7084	2.493e-61	231.0	COG2211@1|root,COG2211@2|Bacteria,2I2UY@201174|Actinobacteria,4EDUM@85010|Pseudonocardiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158188_k127_987109_4	1283299.AUKG01000002_gene5224	3.974e-91	312.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158188_k127_987109_7	572547.Amico_1849	1.813e-51	189.0	COG0537@1|root,COG0537@2|Bacteria,3TB29@508458|Synergistetes	508458|Synergistetes	FG	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158188_k127_987109_6	1150399.AQYK01000001_gene17	1.274e-57	209.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158188_k127_987109_12	1120945.ATUW01000005_gene623	0.0002127	46.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158188_k127_987109_0	1033802.SSPSH_001085	2.408e-140	456.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the class I fructose-bisphosphate aldolase family	alf1	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR25158188_k127_987109_3	710687.KI912270_gene6221	2.251e-91	325.0	COG2040@1|root,COG2040@2|Bacteria,2HS78@201174|Actinobacteria,23AW7@1762|Mycobacteriaceae	201174|Actinobacteria	E	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
SRR25158188_k127_987109_9	1380390.JIAT01000013_gene34	6.326e-42	171.0	2ASH4@1|root,31HXG@2|Bacteria,2HMFJ@201174|Actinobacteria,4CQBD@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158188_k127_987109_2	365528.KB891208_gene2965	1.932e-128	421.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4ES1D@85013|Frankiales	201174|Actinobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158188_k127_987109_1	1380390.JIAT01000015_gene5702	4.269e-131	433.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CP8V@84995|Rubrobacteria	84995|Rubrobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158188_k127_995670_5	562970.Btus_1437	1.059e-34	152.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,2787H@186823|Alicyclobacillaceae	91061|Bacilli	T	Belongs to the peptidase S16 family	-	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158188_k127_995670_4	1089545.KB913037_gene2549	1.096e-67	241.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4E5SR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158188_k127_995670_6	756272.Plabr_4475	7.992e-29	119.0	COG0780@1|root,COG0780@2|Bacteria,2J07W@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158188_k127_995670_1	309801.trd_0921	8.286e-122	397.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,27XRY@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158188_k127_995670_0	1382306.JNIM01000001_gene1290	1.509e-158	512.0	COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi	200795|Chloroflexi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158188_k127_995670_3	644966.Tmar_1145	4.008e-71	255.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WD2S@538999|Clostridiales incertae sedis	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158188_k127_995670_7	1411123.JQNH01000001_gene876	1.245e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,1PU46@1224|Proteobacteria,2UF7Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158188_k127_995670_2	469383.Cwoe_4911	1.865e-88	297.0	COG1118@1|root,COG1118@2|Bacteria,2I3KJ@201174|Actinobacteria,4CPG0@84995|Rubrobacteria	84995|Rubrobacteria	P	TOBE-like domain	-	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE,TOBE_3
## 2410 queries scanned
## Total time (seconds): 5.366498708724976
## Rate: 449.08 q/s