## Wed Feb 18 20:01:02 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158249_bin.17.fa -m mmseqs --output SRR25158249_bin.17 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158249_bin.17 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158249_k127_1001167_2	319795.Dgeo_2136	3.481e-07	59.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1WIX8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM competence damage-inducible protein CinA N-terminal domain	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158249_k127_1001167_0	1385521.N803_09835	2.511e-44	169.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4FFBU@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158249_k127_1001167_1	309801.trd_0526	7.363e-25	107.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158249_k127_1009824_4	868595.Desca_2647	6.459e-53	198.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,261MH@186807|Peptococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158249_k127_1009824_0	1120973.AQXL01000111_gene924	2.834e-173	584.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli,2799W@186823|Alicyclobacillaceae	91061|Bacilli	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158249_k127_1009824_1	1511.CLOST_2132	2.34e-118	391.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25QD5@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158249_k127_1009824_3	309801.trd_0165	1.635e-67	241.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,27XQ4@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158249_k127_1009824_2	298654.FraEuI1c_7105	3.156e-84	306.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4ERIK@85013|Frankiales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158249_k127_1009824_5	882082.SaccyDRAFT_0892	1.979e-27	114.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4DZVK@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR25158249_k127_1009935_1	397278.JOJN01000006_gene1095	0.0002199	50.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4DRMV@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158249_k127_1020846_2	926550.CLDAP_30590	1.573e-11	67.0	COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi	200795|Chloroflexi	H	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158249_k127_1020846_0	1382356.JQMP01000001_gene871	2.152e-114	384.0	COG0447@1|root,COG0447@2|Bacteria,2G66W@200795|Chloroflexi,27Y0G@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158249_k127_1020846_1	383372.Rcas_1310	5.552e-46	172.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,3782T@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158249_k127_1036507_1	55952.BU52_07540	3.771e-43	167.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_1036507_0	1227495.C487_00905	2.801e-60	223.0	COG1404@1|root,COG3979@1|root,arCOG00702@2157|Archaea,arCOG07581@2157|Archaea,2XSZR@28890|Euryarchaeota,23U34@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
SRR25158249_k127_1041282_4	640081.Dsui_1002	5.238e-07	58.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,2WEH2@28216|Betaproteobacteria,2KUPJ@206389|Rhodocyclales	206389|Rhodocyclales	S	BAAT Acyl-CoA thioester hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158249_k127_1041282_0	1120948.KB903217_gene1070	1.282e-106	361.0	COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,4EF6C@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158249_k127_1041282_5	1123261.AXDW01000001_gene1243	0.0002703	51.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,1S3YJ@1236|Gammaproteobacteria,1X6S3@135614|Xanthomonadales	135614|Xanthomonadales	K	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_1041282_6	1381123.AYOD01000015_gene2367	0.0005938	52.0	COG0454@1|root,COG0456@2|Bacteria,1N7DW@1224|Proteobacteria,2VERR@28211|Alphaproteobacteria,43I4V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_1041282_3	1223523.H340_14456	7.191e-08	64.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158249_k127_1041282_1	1380393.JHVP01000001_gene2456	5.1e-35	148.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25,Methyltransf_31
SRR25158249_k127_1041282_2	1128421.JAGA01000002_gene1044	1.341e-30	126.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_1043525_1	1172188.KB911825_gene3706	7.94e-22	99.0	2CEFP@1|root,2ZGIZ@2|Bacteria,2GT06@201174|Actinobacteria,4FJJE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1043525_0	525904.Tter_1713	2.923e-50	194.0	COG1680@1|root,COG1680@2|Bacteria,2NRI6@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158249_k127_1065496_2	65497.JODV01000006_gene940	1.583e-08	59.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4E08Y@85010|Pseudonocardiales	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158249_k127_1065496_0	1128421.JAGA01000003_gene2970	3.456e-134	438.0	COG0498@1|root,COG0498@2|Bacteria,2NP4T@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0546,iSB619.SA_RS06615,iYO844.BSU32250	PALP
SRR25158249_k127_1065496_1	635013.TherJR_2113	1.251e-36	158.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
SRR25158249_k127_1071222_2	1208919.CDSE_0739	5.334e-08	55.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,1KPQW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158249_k127_1071222_0	383372.Rcas_1491	4.844e-81	282.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,375EH@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158249_k127_1071222_1	211114.JOEF01000009_gene1706	7.476e-11	74.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158249_k127_1096748_0	1156919.QWC_24887	1.271e-98	327.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VMEA@28216|Betaproteobacteria,3T23W@506|Alcaligenaceae	28216|Betaproteobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	ydaF_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158249_k127_1096748_1	479434.Sthe_3071	8.673e-70	251.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_1096748_2	1082933.MEA186_23816	7.916e-12	74.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
SRR25158249_k127_1102589_1	1173027.Mic7113_4330	2.589e-29	120.0	2EZ26@1|root,33S8M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1102589_0	266117.Rxyl_3202	3.774e-139	451.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158249_k127_1109341_0	479434.Sthe_0805	1.376e-177	564.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,27Y57@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158249_k127_1109341_1	326427.Cagg_0660	3.898e-94	324.0	COG4586@1|root,COG4586@2|Bacteria,2G88B@200795|Chloroflexi,376NY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_1131020_0	754252.PFREUD_08290	2.08e-107	355.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DPJ3@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158249_k127_1131020_1	926569.ANT_20410	3.549e-65	236.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_1131020_2	479435.Kfla_7040	3.532e-62	237.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4DR1B@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158249_k127_1132090_1	1210046.B277_03655	3.037e-55	205.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2HXQA@201174|Actinobacteria,4FHIS@85021|Intrasporangiaceae	201174|Actinobacteria	K	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158249_k127_1132090_0	47763.JNZA01000035_gene2538	2.299e-79	283.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158249_k127_1152240_3	1122132.AQYH01000016_gene2877	2.279e-50	184.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,4B7K7@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Nucleoside	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158249_k127_1152240_2	1313172.YM304_29460	4.229e-56	208.0	COG5012@1|root,COG5012@2|Bacteria,2GKAY@201174|Actinobacteria	201174|Actinobacteria	S	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158249_k127_1152240_0	543632.JOJL01000035_gene5071	4.795e-91	308.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1152240_1	926550.CLDAP_25210	1.214e-87	297.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158249_k127_115382_0	1121423.JONT01000011_gene259	1.362e-48	196.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_115382_1	1254432.SCE1572_11880	6.616e-26	117.0	COG0500@1|root,COG5653@1|root,COG2226@2|Bacteria,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,42VU5@68525|delta/epsilon subdivisions,2WSGU@28221|Deltaproteobacteria,2YXKC@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158249_k127_1161395_5	1032480.MLP_04500	2.291e-69	244.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4DPE4@85009|Propionibacteriales	201174|Actinobacteria	E	glycine cleavage T protein (aminomethyl transferase)	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158249_k127_1161395_2	1183438.GKIL_0560	1.956e-103	355.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158249_k127_1161395_3	1380390.JIAT01000010_gene4234	2.84e-99	334.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4CS9P@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158249_k127_1161395_1	1463825.JNXC01000023_gene4894	2.736e-116	384.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158249_k127_1161395_4	101510.RHA1_ro02950	1.081e-76	286.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4FX2S@85025|Nocardiaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158249_k127_1161395_6	383372.Rcas_2834	4.183e-50	181.0	COG4154@1|root,COG4154@2|Bacteria	2|Bacteria	G	fucose binding	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
SRR25158249_k127_1161395_0	1380356.JNIK01000017_gene3020	1.277e-136	451.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158249_k127_1161395_7	158500.BV97_04496	8.677e-35	135.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TS0V@28211|Alphaproteobacteria,2KEFP@204457|Sphingomonadales	204457|Sphingomonadales	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158249_k127_1174206_1	1408438.JADD01000005_gene1207	7.846e-27	119.0	COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,27DUS@186827|Aerococcaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158249_k127_1174206_0	479434.Sthe_2722	1.147e-27	127.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158249_k127_1174206_2	471853.Bcav_1553	2.233e-16	85.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158249_k127_1174206_3	765420.OSCT_0974	3.237e-08	57.0	COG0484@1|root,COG0526@1|root,COG0484@2|Bacteria,COG0526@2|Bacteria,2G737@200795|Chloroflexi,375V3@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DnaJ
SRR25158249_k127_1182573_1	1203605.HMPREF1531_01519	5.328e-31	123.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4DNN5@85009|Propionibacteriales	201174|Actinobacteria	O	Cytochrome C assembly protein	resC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158249_k127_1182573_2	1380347.JNII01000008_gene4382	4.128e-09	64.0	COG4961@1|root,COG4961@2|Bacteria,2IS3K@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158249_k127_1182573_0	1101188.KI912157_gene73	4.855e-46	180.0	COG4655@1|root,COG4655@2|Bacteria	2|Bacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
SRR25158249_k127_1192336_3	512565.AMIS_62810	0.0002622	49.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4D9VM@85008|Micromonosporales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158249_k127_1192336_2	871963.Desdi_2527	4.118e-47	180.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,261I9@186807|Peptococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158249_k127_1192336_1	1158318.ATXC01000001_gene573	8.977e-70	260.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158249_k127_1192336_0	292459.STH3140	1.508e-83	303.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia	186801|Clostridia	J	elongation factor g	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158249_k127_119371_2	485913.Krac_7776	0.000828	50.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158249_k127_119371_0	926550.CLDAP_41140	5.818e-72	254.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158249_k127_119371_1	574087.Acear_1609	1.449e-07	55.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WBE9@53433|Halanaerobiales	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158249_k127_1196025_0	1380390.JIAT01000001_gene5076	5.622e-86	299.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CRQW@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158249_k127_1196025_1	1236902.ANAS01000042_gene2249	1.134e-66	235.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4EH9J@85012|Streptosporangiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	-	-	-	-	-	-	-	-	-	-	-	-	DUF1989,FAO_M,GCV_T,GCV_T_C
SRR25158249_k127_1198596_1	485913.Krac_6107	1.564e-68	235.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158249_k127_1198596_0	1382356.JQMP01000003_gene2254	0.0	1347.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,27Y0B@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158249_k127_1199486_4	42256.RradSPS_2494	1.902e-09	67.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158249_k127_1199486_2	1521187.JPIM01000004_gene3042	7.131e-93	325.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158249_k127_1199486_0	1184607.AUCHE_05_04270	0.0	1563.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158249_k127_1199486_1	1297742.A176_06066	2.162e-180	571.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,42RN7@68525|delta/epsilon subdivisions,2WNNX@28221|Deltaproteobacteria,2Z317@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.14,1.2.1.46	ko:K00008,ko:K00148,ko:K18369	ko00040,ko00051,ko00625,ko00640,ko00680,ko01100,ko01120,ko01200,map00040,map00051,map00625,map00640,map00680,map01100,map01120,map01200	M00014	R00604,R00875,R01896,R10703	RC00085,RC00102,RC00188,RC00545	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158249_k127_1199486_3	1125863.JAFN01000001_gene2044	1.657e-43	161.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
SRR25158249_k127_1203868_0	945713.IALB_0421	3.443e-90	308.0	COG1294@1|root,COG1294@2|Bacteria	2|Bacteria	C	oxidative phosphorylation	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120	Cyt_bd_oxida_II
SRR25158249_k127_1203868_1	945713.IALB_0420	6.523e-35	140.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158249_k127_1208506_3	1380346.JNIH01000060_gene954	0.0003623	53.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158249_k127_1208506_2	710111.FraQA3DRAFT_5722	5.361e-50	189.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4ES8E@85013|Frankiales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158249_k127_1208506_1	469383.Cwoe_4700	4.317e-114	379.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPP6@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158249_k127_1208506_0	1051632.TPY_3590	1.533e-150	494.0	COG0247@1|root,COG0479@1|root,COG2181@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158249_k127_1220909_0	1192034.CAP_7842	6.242e-39	155.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158249_k127_1220909_1	224308.BSU35210	4.032e-34	148.0	COG0477@1|root,COG2814@2|Bacteria,1U4EP@1239|Firmicutes,4HAZC@91061|Bacilli,1ZC4J@1386|Bacillus	91061|Bacilli	P	-transporter	yvkA	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158249_k127_1229518_8	312284.A20C1_09434	1.722e-54	194.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria	201174|Actinobacteria	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158249_k127_1229518_5	312284.A20C1_09439	1.075e-86	301.0	COG2971@1|root,COG2971@2|Bacteria	2|Bacteria	G	N-acetylglucosamine kinase activity	gspK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931	2.7.1.8	ko:K18676	ko00520,ko01100,map00520,map01100	-	R01961	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	BcrAD_BadFG
SRR25158249_k127_1229518_6	1713.JOFV01000009_gene381	5.864e-84	285.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria	201174|Actinobacteria	S	protein containing SIS (Sugar isomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158249_k127_1229518_1	312284.A20C1_09449	1.286e-175	561.0	COG3525@1|root,COG3525@2|Bacteria,2GM4H@201174|Actinobacteria	201174|Actinobacteria	G	beta-N-acetylglucosaminidase	-	-	3.2.1.35	ko:K01197	ko00531,ko01100,map00531,map01100	M00076,M00077	R07824,R07825,R10905	-	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	-	-	F5_F8_type_C,FIVAR,Glyco_hydro_20b,NAGidase
SRR25158249_k127_1229518_0	312284.A20C1_09454	7.714e-188	604.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158249_k127_1229518_4	1227352.C173_07182	2.247e-99	336.0	COG1175@1|root,COG1175@2|Bacteria,1TTCE@1239|Firmicutes,4IQMV@91061|Bacilli,276GK@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158249_k127_1229518_2	312284.A20C1_09464	1.134e-126	418.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10202	ko02010,map02010	M00205,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.18	-	-	BPD_transp_1
SRR25158249_k127_1229518_3	745776.DGo_CA2873	4.648e-118	394.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	cmr	-	2.7.4.9	ko:K00943,ko:K08217,ko:K18833	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.2,2.A.1.21.22	-	-	MFS_1,MFS_3
SRR25158249_k127_1229518_11	255470.cbdbB6	5.145e-14	80.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.4.21.88	ko:K01356,ko:K22299	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03000,ko03400	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_S24
SRR25158249_k127_1229518_7	208444.JNYY01000001_gene4967	7.832e-63	229.0	COG5649@1|root,COG5649@2|Bacteria,2IHVG@201174|Actinobacteria,4E7I7@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158249_k127_1229518_9	479432.Sros_0222	2.779e-46	181.0	COG1670@1|root,COG1670@2|Bacteria,2H4AD@201174|Actinobacteria,4EJIU@85012|Streptosporangiales	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1229518_13	292459.STH3155	2.989e-05	55.0	COG4454@1|root,COG4454@2|Bacteria,1U5BP@1239|Firmicutes,257DV@186801|Clostridia	186801|Clostridia	P	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158249_k127_1229518_12	1317124.DW2_09876	1.65e-06	57.0	COG1309@1|root,COG1309@2|Bacteria,1RING@1224|Proteobacteria,2VFGJ@28211|Alphaproteobacteria,2XP3I@285107|Thioclava	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158249_k127_1230364_2	1304865.JAGF01000001_gene21	5.778e-06	50.0	2DBV7@1|root,2ZB9P@2|Bacteria,2GTSP@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158249_k127_1230364_0	219305.MCAG_00811	8.121e-59	207.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria,4DERE@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_1230364_1	219305.MCAG_00213	6.258e-18	85.0	2C1XE@1|root,301BZ@2|Bacteria,2IGAE@201174|Actinobacteria,4DCZU@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1256850_0	1045009.AFXQ01000015_gene2462	6.468e-115	383.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,1W80J@1268|Micrococcaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158249_k127_1256850_1	1089552.KI911559_gene1300	3.902e-47	176.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,2TUNH@28211|Alphaproteobacteria,2JRQ5@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158249_k127_1259419_3	880072.Desac_0381	2.162e-14	78.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,43BI6@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158249_k127_1259419_0	644966.Tmar_0951	7.876e-145	471.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158249_k127_1259419_2	1382356.JQMP01000003_gene2333	3.361e-20	100.0	COG0511@1|root,COG0511@2|Bacteria,2G94M@200795|Chloroflexi,27YJ8@189775|Thermomicrobia	189775|Thermomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158249_k127_1259419_1	309801.trd_1623	1.264e-36	150.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi,27XWK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158249_k127_1259857_0	552811.Dehly_1213	2.892e-38	158.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1259857_1	765420.OSCT_2937	0.00054	51.0	2EHBQ@1|root,33B3J@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158249_k127_1263833_0	526227.Mesil_0256	1.493e-75	265.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
SRR25158249_k127_1263833_2	243164.DET1620	4.891e-27	126.0	COG1277@1|root,COG1277@2|Bacteria,2GAJV@200795|Chloroflexi,34CKA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158249_k127_1263833_1	1497679.EP56_00185	1.934e-43	167.0	COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,26IQQ@186820|Listeriaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	yxlF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158249_k127_1289071_0	1382356.JQMP01000001_gene1192	0.0	1143.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,27XND@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158249_k127_1289071_1	709986.Deima_2140	2.484e-39	165.0	COG5495@1|root,COG5495@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158249_k127_1289071_2	28042.GU90_14215	3.178e-17	88.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4E30H@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158249_k127_1301168_0	485913.Krac_5051	5.267e-11	73.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158249_k127_1318904_1	326427.Cagg_3406	8.311e-10	70.0	COG0526@1|root,COG0526@2|Bacteria,2GACV@200795|Chloroflexi,375FU@32061|Chloroflexia	32061|Chloroflexia	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
SRR25158249_k127_1318904_0	196367.JNFG01000202_gene2410	1.369e-52	192.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_1341100_0	479434.Sthe_1559	4.015e-07	63.0	COG3299@1|root,COG3299@2|Bacteria,2GA9P@200795|Chloroflexi,27YCN@189775|Thermomicrobia	189775|Thermomicrobia	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1344048_1	479434.Sthe_2399	2.023e-78	272.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,27XQF@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158249_k127_1344048_2	1268303.RHODMAR_4651	1.411e-28	119.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4G2IE@85025|Nocardiaceae	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158249_k127_1344048_3	157783.LK03_13700	8.062e-06	55.0	COG4454@1|root,COG4454@2|Bacteria,1N7A1@1224|Proteobacteria	1224|Proteobacteria	P	Copper-binding protein	cusF	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158249_k127_1344048_0	543632.JOJL01000026_gene2371	1.101e-85	306.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DCE9@85008|Micromonosporales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158249_k127_1354892_5	1128421.JAGA01000001_gene2184	1.359e-22	113.0	COG1082@1|root,COG1082@2|Bacteria,2NQSY@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	iolE	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158249_k127_1354892_2	525904.Tter_2265	4.067e-112	372.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158249_k127_1354892_4	103733.JNYO01000014_gene3806	8.597e-47	173.0	COG1670@1|root,COG1670@2|Bacteria,2II7F@201174|Actinobacteria,4E3ZH@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_1354892_0	1283283.ATXA01000001_gene364	3.371e-140	456.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4ESDF@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158249_k127_1354892_1	479434.Sthe_2371	4.649e-117	383.0	COG2189@1|root,COG2189@2|Bacteria,2G5WR@200795|Chloroflexi	200795|Chloroflexi	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158249_k127_1354892_3	525368.HMPREF0591_0450	1.009e-66	231.0	COG4405@1|root,COG4405@2|Bacteria,2IFEU@201174|Actinobacteria,23F81@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_1354892_6	1396141.BATP01000059_gene2444	1.156e-18	90.0	2FF51@1|root,34735@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1366171_2	269796.Rru_A3354	2.82e-36	153.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,2JS6Z@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158249_k127_1366171_1	1382356.JQMP01000004_gene319	6.679e-116	392.0	COG3653@1|root,COG3653@2|Bacteria,2G86A@200795|Chloroflexi,27ZD5@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158249_k127_1366171_0	1382356.JQMP01000003_gene2236	1.568e-158	530.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158249_k127_1366171_3	1487953.JMKF01000062_gene4785	1.375e-09	70.0	2EZ26@1|root,33S8M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1371167_0	1235796.C815_01739	1.459e-115	392.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes	1239|Firmicutes	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158249_k127_1395293_2	1121362.A605_09560	1.118e-05	59.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,22KGG@1653|Corynebacteriaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRR25158249_k127_1395293_1	794903.OPIT5_22495	8.835e-06	60.0	COG3307@1|root,COG3307@2|Bacteria,46YCP@74201|Verrucomicrobia,3K9BC@414999|Opitutae	414999|Opitutae	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158249_k127_1395293_0	1320556.AVBP01000022_gene2004	9.448e-07	51.0	COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,2TSBS@28211|Alphaproteobacteria,43NYR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Glycosyl transferase WecB/TagA/CpsF family	MA20_06090	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRR25158249_k127_1397298_0	981384.AEYW01000001_gene1562	1.55e-101	365.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
SRR25158249_k127_1401879_1	66373.JOFQ01000017_gene1377	1.713e-25	119.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria	201174|Actinobacteria	M	Lipid A biosynthesis	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158249_k127_1401879_2	351607.Acel_1354	7.62e-24	115.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4ESDA@85013|Frankiales	201174|Actinobacteria	M	lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158249_k127_1401879_0	479434.Sthe_1716	6.755e-187	591.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia	189775|Thermomicrobia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158249_k127_1406237_8	266117.Rxyl_0427	1.214e-26	114.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,4CTJ6@84995|Rubrobacteria	84995|Rubrobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158249_k127_1406237_3	1298863.AUEP01000005_gene2467	3.034e-75	260.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria,4DV4X@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158249_k127_1406237_5	1120959.ATXF01000005_gene1353	9.434e-53	194.0	2BVHU@1|root,32QW6@2|Bacteria,2HRWT@201174|Actinobacteria	201174|Actinobacteria	S	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158249_k127_1406237_0	255470.cbdbA765	5.126e-170	548.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,34D2R@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158249_k127_1406237_7	1380356.JNIK01000015_gene2546	5.091e-32	136.0	2BPDR@1|root,32I5V@2|Bacteria,2H6IS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1406237_9	1283299.AUKG01000002_gene3940	8.069e-20	104.0	COG3266@1|root,COG3266@2|Bacteria,2GW3B@201174|Actinobacteria,4CSAK@84995|Rubrobacteria	84995|Rubrobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1406237_2	926560.KE387027_gene1021	3.904e-88	314.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1406237_1	172088.AUGA01000019_gene1981	6.174e-151	496.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,3JVT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
SRR25158249_k127_1406237_6	1142394.PSMK_17130	4.403e-37	155.0	COG1018@1|root,COG1018@2|Bacteria,2IXKZ@203682|Planctomycetes	203682|Planctomycetes	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	NAD_binding_1
SRR25158249_k127_1406237_4	324602.Caur_2963	2.358e-66	235.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,376J5@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158249_k127_1413077_1	926569.ANT_30900	2.027e-49	179.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158249_k127_1413077_0	926569.ANT_01400	1.044e-139	454.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158249_k127_1427907_0	1370121.AUWS01000033_gene4232	2.548e-155	509.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,234CE@1762|Mycobacteriaceae	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158249_k127_1434522_3	1380391.JIAS01000003_gene1907	7.77e-26	112.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria,2JZCC@204441|Rhodospirillales	204441|Rhodospirillales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158249_k127_1434522_0	105420.BBPO01000005_gene2881	1.3e-56	211.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,2NHGX@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	allR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158249_k127_1434522_2	935866.JAER01000017_gene4353	5.135e-27	129.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,DUF11,Laminin_G_3,Malectin
SRR25158249_k127_1434522_1	1121948.AUAC01000006_gene518	2.234e-46	192.0	COG1361@1|root,COG2885@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SRR25158249_k127_1442910_0	935548.KI912159_gene1669	7.119e-106	353.0	COG1172@1|root,COG1172@2|Bacteria,1MVKQ@1224|Proteobacteria,2TTT3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158249_k127_1442910_1	1082933.MEA186_20774	1.774e-103	361.0	COG1172@1|root,COG1172@2|Bacteria,1PRXF@1224|Proteobacteria,2TV5I@28211|Alphaproteobacteria,43RE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158249_k127_1442910_2	357808.RoseRS_2512	7.914e-67	252.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi,375NG@32061|Chloroflexia	32061|Chloroflexia	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158249_k127_1442910_3	35754.JNYJ01000031_gene6985	5.367e-57	208.0	COG2188@1|root,COG2188@2|Bacteria,2IK3E@201174|Actinobacteria,4DDPG@85008|Micromonosporales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158249_k127_1442910_4	502025.Hoch_1477	6.083e-43	171.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,430VJ@68525|delta/epsilon subdivisions,2WVQI@28221|Deltaproteobacteria,2Z0VP@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158249_k127_1461039_2	290397.Adeh_2624	5.627e-55	199.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158249_k127_1461039_5	596324.TREVI0001_0477	5.105e-21	110.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
SRR25158249_k127_1461039_4	880073.Calab_0133	1.507e-31	145.0	COG0860@1|root,COG1361@1|root,COG3858@1|root,COG0860@2|Bacteria,COG1361@2|Bacteria,COG3858@2|Bacteria,2NQII@2323|unclassified Bacteria	2|Bacteria	M	Glyco_18	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K20276	ko00550,ko01100,ko01502,ko01503,ko02020,ko02024,map00550,map01100,map01502,map01503,map02020,map02024	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_2,Cu_amine_oxidN1,GBS_Bsp-like,Glyco_hydro_18,Glyco_hydro_25,Peptidase_C39_2,SH3_5,VanY,YSIRK_signal
SRR25158249_k127_1461039_3	1128421.JAGA01000002_gene1831	6.747e-40	166.0	COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	1.1.1.133,5.1.3.13,5.1.3.26	ko:K00067,ko:K01790,ko:K19997	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_1929,iEcHS_1320.EcHS_A2180,iJN678.rfbD	RmlD_sub_bind
SRR25158249_k127_1461039_0	479434.Sthe_0968	1.542e-111	378.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,27XGB@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158249_k127_1461039_1	309807.SRU_0589	9.832e-60	216.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1FJDI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	MobA-like NTP transferase domain	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158249_k127_1467030_0	269799.Gmet_1217	4.207e-50	187.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,43U1Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158249_k127_1467030_1	926569.ANT_11700	1.663e-24	106.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158249_k127_1478623_1	743718.Isova_2798	1.776e-19	99.0	COG0308@1|root,COG0308@2|Bacteria,2ID1N@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1478623_0	367299.JOEE01000001_gene1484	1.208e-24	116.0	COG0308@1|root,COG0308@2|Bacteria,2ID1N@201174|Actinobacteria,4FIRF@85021|Intrasporangiaceae	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1480150_1	221360.RS9917_07265	2.383e-09	68.0	COG0484@1|root,COG0484@2|Bacteria,1G2FB@1117|Cyanobacteria,1GZUP@1129|Synechococcus	1117|Cyanobacteria	O	Molecular chaperone	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
SRR25158249_k127_1480150_0	373903.Hore_01750	2.197e-47	182.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,24CUE@186801|Clostridia,3WBDN@53433|Halanaerobiales	186801|Clostridia	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158249_k127_1481281_5	324602.Caur_1536	2.792e-97	332.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,2G64W@200795|Chloroflexi,376VC@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase
SRR25158249_k127_1481281_4	1464048.JNZS01000004_gene1368	2.702e-119	392.0	COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,4DAZ2@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158249_k127_1481281_0	1150864.MILUP08_40857	2.886e-189	604.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4D8NC@85008|Micromonosporales	201174|Actinobacteria	G	N-terminal of TM subunit in PBP-dependent ABC transporters	malF	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,TM_PBP2_N
SRR25158249_k127_1481281_3	644283.Micau_0769	4.441e-131	431.0	COG2182@1|root,COG2182@2|Bacteria,2HU1V@201174|Actinobacteria,4DAF2@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
SRR25158249_k127_1481281_6	383372.Rcas_1849	5.069e-82	287.0	COG1609@1|root,COG1609@2|Bacteria,2GAIK@200795|Chloroflexi,377B5@32061|Chloroflexia	32061|Chloroflexia	K	periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
SRR25158249_k127_1481281_10	525904.Tter_1129	4.966e-15	86.0	COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_Tnp_IS630
SRR25158249_k127_1481281_7	9371.XP_004704422.1	4.783e-59	223.0	COG0179@1|root,KOG1535@2759|Eukaryota,38DXI@33154|Opisthokonta,3BCS8@33208|Metazoa,3CYTW@33213|Bilateria,486N8@7711|Chordata,493BZ@7742|Vertebrata,3JAYE@40674|Mammalia,34T44@311790|Afrotheria	33208|Metazoa	Q	Fumarylacetoacetate hydrolase domain-containing protein	FAHD2A	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158249_k127_1481281_1	497964.CfE428DRAFT_4081	2.614e-161	514.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158249_k127_1481281_2	997346.HMPREF9374_0644	3.682e-145	487.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,27B3G@186824|Thermoactinomycetaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158249_k127_1481281_8	1303518.CCALI_02006	4.116e-39	158.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
SRR25158249_k127_1481281_9	935839.JAGJ01000032_gene34	6.405e-32	143.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4F3AS@85017|Promicromonosporaceae	201174|Actinobacteria	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158249_k127_148223_1	1380393.JHVP01000015_gene4189	9.087e-110	364.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4EUG0@85013|Frankiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_148223_2	656024.FsymDg_4270	1.218e-101	337.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4EUMB@85013|Frankiales	201174|Actinobacteria	C	Cysteine-rich domain	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158249_k127_148223_0	1123320.KB889719_gene7287	3.94e-203	655.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria	201174|Actinobacteria	C	Iron-sulfur cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158249_k127_148223_6	1463857.JOFZ01000016_gene1117	1.879e-54	215.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158249_k127_148223_7	351160.RRC323	4.954e-15	84.0	COG0589@1|root,arCOG02053@2157|Archaea,2XZV8@28890|Euryarchaeota	2157|Archaea	T	Universal stress protein family	uspA-5	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158249_k127_148223_4	479434.Sthe_2605	2.614e-63	227.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia	189775|Thermomicrobia	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158249_k127_148223_3	1003195.SCAT_5044	4.721e-83	298.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158249_k127_148223_8	1121940.AUDZ01000006_gene297	4.664e-12	71.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,1XMFT@135619|Oceanospirillales	135619|Oceanospirillales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158249_k127_148223_5	479434.Sthe_1941	1.848e-60	216.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_1484565_3	1392501.JIAC01000001_gene574	2.238e-17	87.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4H222@909932|Negativicutes	909932|Negativicutes	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158249_k127_1484565_1	926550.CLDAP_03710	8.181e-62	224.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158249_k127_1484565_0	1385515.N791_06190	1.204e-156	516.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1X44Q@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158249_k127_1484565_4	479434.Sthe_1250	2.913e-09	62.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia	189775|Thermomicrobia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158249_k127_1484565_2	479434.Sthe_1249	4.166e-21	98.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158249_k127_1486006_0	208439.AJAP_24810	3.167e-81	277.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4DZ5Q@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158249_k127_1486006_1	661478.OP10G_4092	1.65e-49	183.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
SRR25158249_k127_1486006_2	926564.KI911726_gene2108	2.613e-48	175.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4F47A@85017|Promicromonosporaceae	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
SRR25158249_k127_1488374_0	1192034.CAP_8329	2.401e-155	505.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWPS@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158249_k127_1488374_1	926550.CLDAP_19560	3.328e-25	110.0	2EB0S@1|root,3351M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1488374_2	84531.JMTZ01000038_gene3637	0.000144	50.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RZ3X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein and some similarities with VgrG protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SRR25158249_k127_1489669_1	196162.Noca_4614	4.527e-39	156.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DN3F@85009|Propionibacteriales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_1489669_2	1192034.CAP_0198	5.939e-34	135.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158249_k127_1489669_0	390989.JOEG01000013_gene2562	1.744e-92	309.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158249_k127_1495965_1	1123322.KB904652_gene584	3.887e-34	150.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158249_k127_1495965_0	323848.Nmul_A2657	7.597e-159	511.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,371QX@32003|Nitrosomonadales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158249_k127_1495965_2	1463887.KL590019_gene8034	7.749e-34	151.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158249_k127_1504909_1	316274.Haur_0438	1.441e-34	141.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158249_k127_1504909_2	479434.Sthe_0715	4.215e-27	117.0	COG0576@1|root,COG0576@2|Bacteria,2G6WR@200795|Chloroflexi,27YDX@189775|Thermomicrobia	189775|Thermomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158249_k127_1504909_0	1382306.JNIM01000001_gene1384	1.313e-73	251.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158249_k127_151374_1	591158.SSMG_08050	9.427e-32	129.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158249_k127_151374_2	224325.AF_1672	4.976e-11	74.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
SRR25158249_k127_151374_0	338963.Pcar_2954	1.7e-85	299.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,43U7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
SRR25158249_k127_1522419_4	1227484.C471_12936	5.145e-21	104.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158249_k127_1522419_2	1536774.H70357_27195	3.245e-34	146.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158249_k127_1522419_0	67315.JOBD01000003_gene6000	2.679e-125	423.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria	201174|Actinobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
SRR25158249_k127_1522419_1	661478.OP10G_2723	6.485e-72	248.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SRR25158249_k127_1539349_6	1123253.AUBD01000007_gene610	1.661e-12	75.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1X3WW@135614|Xanthomonadales	135614|Xanthomonadales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158249_k127_1539349_7	1123258.AQXZ01000017_gene3865	3.197e-07	60.0	COG1714@1|root,COG1714@2|Bacteria,2GS9U@201174|Actinobacteria,4G38W@85025|Nocardiaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158249_k127_1539349_5	1146883.BLASA_0888	8.896e-15	83.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria,4EW8F@85013|Frankiales	201174|Actinobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158249_k127_1539349_1	525904.Tter_1351	3.454e-94	327.0	COG0075@1|root,COG0075@2|Bacteria,2NP52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	dhsS	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.sll1559,iSB619.SA_RS08700	Aminotran_5
SRR25158249_k127_1539349_0	1128421.JAGA01000001_gene2412	2.24e-146	481.0	COG1052@1|root,COG1052@2|Bacteria,2NS44@2323|unclassified Bacteria	2|Bacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158249_k127_1539349_2	95619.PM1_0223520	1.214e-23	112.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1SAR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158249_k127_1539349_3	479434.Sthe_1588	2.898e-20	101.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,27XNH@189775|Thermomicrobia	189775|Thermomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158249_k127_1550400_0	634956.Geoth_0173	4.274e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1WETT@129337|Geobacillus	91061|Bacilli	K	binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_1550400_1	529818.AMSG_10909T0	1.366e-22	108.0	KOG0379@1|root,KOG0379@2759|Eukaryota	2759|Eukaryota	P	nitrile biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_3,Kelch_4
SRR25158249_k127_1550508_1	593907.Celgi_3028	1.342e-83	291.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4F2AT@85016|Cellulomonadaceae	201174|Actinobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158249_k127_1550508_0	263358.VAB18032_27071	4.465e-112	403.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158249_k127_1550508_2	469383.Cwoe_5925	2.379e-54	204.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158249_k127_1550508_3	1382356.JQMP01000001_gene867	7.566e-30	134.0	COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158249_k127_1557435_1	1382306.JNIM01000001_gene4140	1.404e-72	276.0	COG0240@1|root,COG0240@2|Bacteria,2G5W5@200795|Chloroflexi	200795|Chloroflexi	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158249_k127_1557435_0	525904.Tter_1758	2.408e-141	465.0	COG1160@1|root,COG1160@2|Bacteria,2NNTW@2323|unclassified Bacteria	2|Bacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.399,1.1.1.95	ko:K00058,ko:K03977	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147	-	-	-	KH_dom-like,MMR_HSR1
SRR25158249_k127_1557435_2	635013.TherJR_1590	3.455e-10	64.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158249_k127_1575794_0	382464.ABSI01000013_gene1570	3.388e-71	258.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
SRR25158249_k127_1575794_2	1229909.NSED_04975	1.921e-14	86.0	COG1361@1|root,arCOG04500@1|root,arCOG02079@2157|Archaea,arCOG04500@2157|Archaea	2157|Archaea	O	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CARDB,NosD,S_layer_C
SRR25158249_k127_1575794_1	1030157.AFMP01000062_gene3609	6.748e-17	94.0	COG3210@1|root,COG3210@2|Bacteria,1NC4M@1224|Proteobacteria	1224|Proteobacteria	U	Protein of unknown function (DUF642)	-	-	-	-	-	-	-	-	-	-	-	-	DUF642
SRR25158249_k127_1600720_0	2045.KR76_03035	1.689e-61	224.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4DMXU@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_1600720_1	266117.Rxyl_0847	3.901e-18	96.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	84995|Rubrobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158249_k127_1601919_2	696369.KI912183_gene1155	6.512e-42	163.0	COG0530@1|root,COG0530@2|Bacteria,1UQT7@1239|Firmicutes,258JC@186801|Clostridia,260UA@186807|Peptococcaceae	186801|Clostridia	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158249_k127_1601919_1	525904.Tter_0782	1.841e-96	338.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158249_k127_1601919_3	479434.Sthe_2302	1.007e-39	169.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158249_k127_1601919_0	479434.Sthe_0337	3.833e-214	682.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158249_k127_1615531_0	644966.Tmar_0135	1.389e-95	331.0	COG0617@1|root,COG2254@1|root,COG0617@2|Bacteria,COG2254@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WCIJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158249_k127_1615531_2	741091.Rahaq_2154	0.0003245	49.0	COG0457@1|root,COG3118@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,1MVB8@1224|Proteobacteria,1RPSN@1236|Gammaproteobacteria,3FH6E@34037|Rahnella	1236|Gammaproteobacteria	O	cellulose synthase	bcsC	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_8
SRR25158249_k127_1615531_1	575606.HMPREF0525_00817	1.757e-81	281.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158249_k127_1617845_1	926569.ANT_31630	4.111e-72	249.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158249_k127_1617845_0	42256.RradSPS_1174	1.366e-139	471.0	COG1216@1|root,COG4122@1|root,COG4641@1|root,COG1216@2|Bacteria,COG4122@2|Bacteria,COG4641@2|Bacteria,2IT06@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158249_k127_1640889_0	1462527.CCDM010000001_gene1792	1.962e-203	654.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,23JPU@182709|Oceanobacillus	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158249_k127_1640889_1	309801.trd_1375	1.903e-121	400.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,27Y4E@189775|Thermomicrobia	189775|Thermomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158249_k127_1640889_2	1048834.TC41_2846	8.954e-06	52.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,27856@186823|Alicyclobacillaceae	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158249_k127_1644307_0	552811.Dehly_0558	2.953e-54	207.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158249_k127_1644307_1	479434.Sthe_0719	9.167e-46	187.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,27XPY@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SRR25158249_k127_1644307_2	340099.Teth39_1999	1.66e-16	87.0	COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,24DRC@186801|Clostridia,42FSZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158249_k127_1656482_2	755732.Fluta_1970	5.266e-05	52.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158249_k127_1656482_0	237368.SCABRO_01998	3.021e-144	484.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158249_k127_1656482_1	269799.Gmet_3344	6.416e-32	134.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43TW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158249_k127_1657587_2	1121035.AUCH01000003_gene1204	0.000447	42.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,2KUCM@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158249_k127_1657587_1	1123371.ATXH01000011_gene69	1.504e-23	111.0	COG2165@1|root,COG2165@2|Bacteria,2GI1E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158249_k127_1657587_0	1121035.AUCH01000003_gene1203	2.601e-56	205.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,2VR8U@28216|Betaproteobacteria,2KWCN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158249_k127_1660553_3	2002.JOEQ01000012_gene5654	2.85e-43	173.0	COG1418@1|root,COG1418@2|Bacteria,2GJPC@201174|Actinobacteria,4EKKH@85012|Streptosporangiales	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158249_k127_1660553_2	593750.Metfor_0971	7.714e-55	206.0	COG1707@1|root,arCOG00813@2157|Archaea,2XT8A@28890|Euryarchaeota,2NAE8@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM amino acid-binding ACT domain protein	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
SRR25158249_k127_1660553_4	1128421.JAGA01000003_gene3418	1.274e-31	130.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_1660553_5	1267535.KB906767_gene4017	9.291e-30	130.0	COG1393@1|root,COG1393@2|Bacteria,3Y7VT@57723|Acidobacteria	57723|Acidobacteria	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
SRR25158249_k127_1660553_1	298655.KI912266_gene2297	5.17e-63	243.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,4EVB8@85013|Frankiales	201174|Actinobacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SRR25158249_k127_1660553_0	357808.RoseRS_4048	3.624e-81	284.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi,376GG@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158249_k127_1662897_0	981384.AEYW01000018_gene3284	7.437e-207	674.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,4NCZM@97050|Ruegeria	28211|Alphaproteobacteria	L	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
SRR25158249_k127_1662897_1	67352.JODS01000011_gene4330	9.389e-34	138.0	COG0477@1|root,COG0477@2|Bacteria,2IIAH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
SRR25158249_k127_1676575_0	1380390.JIAT01000009_gene1863	3.213e-46	175.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	84995|Rubrobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_1676575_1	1048339.KB913029_gene582	1.421e-07	63.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria,4EVJ0@85013|Frankiales	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158249_k127_1679280_2	1229203.KI301992_gene278	2.103e-19	96.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_1679280_0	880073.Calab_0629	1.299e-95	329.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158249_k127_1679280_1	1128421.JAGA01000003_gene3002	1.458e-54	212.0	COG0074@1|root,COG0074@2|Bacteria,2NNZD@2323|unclassified Bacteria	2|Bacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158249_k127_1688906_1	649638.Trad_0936	7.065e-63	231.0	COG1520@1|root,COG1520@2|Bacteria,1WKKN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,SBBP
SRR25158249_k127_1688906_0	1032480.MLP_14770	3.006e-80	276.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4DP1Z@85009|Propionibacteriales	201174|Actinobacteria	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158249_k127_1688906_2	1274.HX89_07620	1.108e-13	77.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,1ZVM0@145357|Dermacoccaceae	201174|Actinobacteria	D	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158249_k127_1694272_1	1382306.JNIM01000001_gene2830	5.485e-25	113.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
SRR25158249_k127_1694272_0	1128421.JAGA01000002_gene1247	9.373e-75	282.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158249_k127_1696163_3	1267533.KB906734_gene3770	5.527e-85	293.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158249_k127_1696163_4	644282.Deba_0535	5.3e-63	243.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158249_k127_1696163_2	485913.Krac_11275	3.331e-88	304.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158249_k127_1696163_1	479435.Kfla_6423	1.346e-123	427.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DNF3@85009|Propionibacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158249_k127_1696163_0	1382306.JNIM01000001_gene774	1.116e-242	761.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158249_k127_1701468_0	485913.Krac_6715	6.513e-97	336.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158249_k127_1702410_2	292459.STH1807	3.495e-93	325.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,24ASU@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
SRR25158249_k127_1702410_3	330214.NIDE3965	2.575e-58	207.0	COG0041@1|root,COG0041@2|Bacteria,3J0P8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158249_k127_1702410_4	292459.STH2026	6.494e-39	153.0	COG1051@1|root,COG1051@2|Bacteria,1V466@1239|Firmicutes,24PBY@186801|Clostridia	186801|Clostridia	F	PFAM NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
SRR25158249_k127_1702410_0	309801.trd_1825	6.72e-151	499.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,27XTS@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158249_k127_1702410_1	1035308.AQYY01000001_gene2445	1.148e-101	349.0	COG1226@1|root,COG1226@2|Bacteria,1V2CY@1239|Firmicutes,24DT6@186801|Clostridia,260Z7@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158249_k127_1702410_5	2002.JOEQ01000023_gene1257	8.583e-17	81.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4EH8P@85012|Streptosporangiales	201174|Actinobacteria	GK	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158249_k127_1707172_1	1174528.JH992898_gene3715	4.551e-44	175.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1JJMP@1189|Stigonemataceae	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158249_k127_1707172_0	383372.Rcas_1960	3.671e-48	196.0	COG0477@1|root,COG2814@2|Bacteria,2G7PR@200795|Chloroflexi,3780D@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_1707172_2	593117.TGAM_0991	8.82e-12	72.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,242M3@183968|Thermococci	183968|Thermococci	S	gtp1 obg	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
SRR25158249_k127_1721749_0	65497.JODV01000007_gene361	7.787e-113	396.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DYKC@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158249_k127_1723439_0	571166.KI421509_gene2039	1.509e-91	308.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158249_k127_1723439_3	671065.MetMK1DRAFT_00005750	2.64e-05	51.0	COG2002@1|root,arCOG00816@2157|Archaea,2XSIJ@28889|Crenarchaeota	28889|Crenarchaeota	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158249_k127_1723439_2	767817.Desgi_2255	4.312e-10	69.0	COG1848@1|root,COG1848@2|Bacteria,1VM3M@1239|Firmicutes,24NDX@186801|Clostridia,2679M@186807|Peptococcaceae	186801|Clostridia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158249_k127_1723439_1	28444.JODQ01000007_gene5411	5.25e-91	310.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158249_k127_1742568_1	469383.Cwoe_4904	1.112e-64	244.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CRYP@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158249_k127_1742568_0	298655.KI912266_gene3133	6.442e-126	411.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4ERGM@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158249_k127_1745948_0	981384.AEYW01000014_gene241	3.705e-91	309.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria,4NAR4@97050|Ruegeria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	xylF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158249_k127_1745948_1	1122182.KB903814_gene3524	5.664e-30	124.0	COG1940@1|root,COG1940@2|Bacteria,2GPEI@201174|Actinobacteria,4DAH2@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158249_k127_175156_0	1306174.JODP01000004_gene978	5.388e-245	793.0	COG2909@1|root,COG2909@2|Bacteria,2IBVA@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_175156_4	134676.ACPL_6880	1.034e-39	157.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria,4DFDP@85008|Micromonosporales	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158249_k127_175156_1	1306174.JODP01000004_gene978	7.455e-157	532.0	COG2909@1|root,COG2909@2|Bacteria,2IBVA@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_175156_2	357808.RoseRS_2189	7.313e-112	372.0	COG0673@1|root,COG0673@2|Bacteria,2G5VJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158249_k127_175156_3	1280390.CBQR020000149_gene3856	2.193e-107	354.0	COG4813@1|root,COG4813@2|Bacteria,1TPZ1@1239|Firmicutes,4HARS@91061|Bacilli,26S59@186822|Paenibacillaceae	91061|Bacilli	G	Trehalose utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
SRR25158249_k127_175156_5	1313172.YM304_11140	6.936e-37	149.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158249_k127_1766982_0	1196323.ALKF01000144_gene1309	0.0005178	53.0	COG1621@1|root,COG2374@1|root,COG3225@1|root,COG1621@2|Bacteria,COG2374@2|Bacteria,COG3225@2|Bacteria,1VE4R@1239|Firmicutes,4HV48@91061|Bacilli,27727@186822|Paenibacillaceae	91061|Bacilli	G	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,DUF5011,Glyco_hydro_59,Metallophos,NAGPA,Pur_ac_phosph_N,SLH
SRR25158249_k127_1806579_3	743718.Isova_2381	3.077e-18	99.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4F5BW@85017|Promicromonosporaceae	201174|Actinobacteria	P	Adenylylsulphate kinase	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158249_k127_1806579_1	743718.Isova_2380	2.815e-110	366.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4F5AZ@85017|Promicromonosporaceae	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158249_k127_1806579_2	743718.Isova_2379	3.239e-101	338.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,4F5K6@85017|Promicromonosporaceae	201174|Actinobacteria	P	Inositol monophosphatase family	cysQ	GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0008934,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019637,GO:0019693,GO:0030145,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050308,GO:0050427,GO:0050897,GO:0052745,GO:0052834,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158249_k127_1806579_0	743718.Isova_2378	2.579e-137	458.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4F41N@85017|Promicromonosporaceae	201174|Actinobacteria	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158249_k127_1813271_1	1380390.JIAT01000011_gene2608	1.428e-75	261.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158249_k127_1813271_4	1027292.HMPREF9372_2352	4.528e-63	226.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,26EI8@186818|Planococcaceae	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158249_k127_1813271_3	935948.KE386495_gene1490	6.848e-69	250.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,42F6V@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158249_k127_1813271_7	880072.Desac_1433	1.2e-32	130.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MQKC@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158249_k127_1813271_8	1496688.ER33_06490	2.089e-11	68.0	COG0257@1|root,COG0257@2|Bacteria,1GAEI@1117|Cyanobacteria,22T6J@167375|Cyanobium	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158249_k127_1813271_6	1449126.JQKL01000050_gene2698	3.208e-54	193.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,26987@186813|unclassified Clostridiales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158249_k127_1813271_5	1382306.JNIM01000001_gene3523	5.476e-57	200.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158249_k127_1813271_2	1382304.JNIL01000001_gene1939	1.353e-71	252.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,2782H@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158249_k127_1813271_0	485913.Krac_12501	1.358e-75	264.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158249_k127_1815258_3	1128421.JAGA01000004_gene2614	3.922e-10	72.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1815258_1	525904.Tter_0025	3.61e-59	221.0	COG1195@1|root,COG1195@2|Bacteria,2NPEJ@2323|unclassified Bacteria	2|Bacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629,ko:K07459	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158249_k127_1815258_0	525904.Tter_0993	7.327e-104	351.0	COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria	2|Bacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158249_k127_1815258_2	525904.Tter_0001	8.876e-49	179.0	COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158249_k127_1816239_0	309801.trd_0370	1.737e-139	464.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	189775|Thermomicrobia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158249_k127_1819655_1	1002340.AFCF01000065_gene28	1.133e-25	111.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158249_k127_1819655_0	1254432.SCE1572_09945	7.272e-93	333.0	COG5555@1|root,COG5555@2|Bacteria,1QX82@1224|Proteobacteria,43CYG@68525|delta/epsilon subdivisions,2X86M@28221|Deltaproteobacteria,2Z3M6@29|Myxococcales	28221|Deltaproteobacteria	N	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
SRR25158249_k127_1821458_1	469383.Cwoe_3631	1.173e-47	174.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158249_k127_1821458_0	35754.JNYJ01000037_gene4695	2.349e-153	490.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158249_k127_1824798_2	1229780.BN381_80027	9.695e-37	147.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,3UWVY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158249_k127_1824798_4	926569.ANT_18000	9.285e-13	72.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158249_k127_1824798_3	926550.CLDAP_23690	5.475e-25	111.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158249_k127_1824798_6	237368.SCABRO_00546	0.0001502	50.0	COG2442@1|root,COG2442@2|Bacteria,2J4DY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158249_k127_1824798_0	685727.REQ_13040	3.172e-78	284.0	COG4805@1|root,COG4805@2|Bacteria,2GJQT@201174|Actinobacteria,4FVD1@85025|Nocardiaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1824798_1	531844.FIC_01252	1.414e-46	174.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,1I213@117743|Flavobacteriia	976|Bacteroidetes	S	Bacteriocin-protection protein	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158249_k127_1824798_5	1268622.AVS7_01110	6.143e-07	52.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,4ACMK@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158249_k127_1840424_1	644966.Tmar_0273	1.64e-62	235.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WCQ8@538999|Clostridiales incertae sedis	186801|Clostridia	H	PFAM Mur ligase family, glutamate ligase domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158249_k127_1840424_0	1382356.JQMP01000003_gene1503	8.854e-79	282.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,27XJT@189775|Thermomicrobia	189775|Thermomicrobia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158249_k127_1840424_3	477974.Daud_0096	5.196e-29	124.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262W6@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158249_k127_1840424_2	1173027.Mic7113_5556	2.127e-61	230.0	COG0265@1|root,COG0265@2|Bacteria,1G17C@1117|Cyanobacteria,1H723@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	hhoA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158249_k127_1843467_1	644966.Tmar_1210	4.912e-08	64.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,3WDPT@538999|Clostridiales incertae sedis	186801|Clostridia	U	TIGRFAM Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158249_k127_1843467_0	367299.JOEE01000003_gene2973	3.217e-36	158.0	COG4655@1|root,COG4655@2|Bacteria,2IAR7@201174|Actinobacteria	201174|Actinobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158249_k127_1843467_2	857293.CAAU_2344	5.449e-05	52.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,36MCG@31979|Clostridiaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158249_k127_1852005_4	356851.JOAN01000032_gene2810	7.973e-36	146.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria,4D9FS@85008|Micromonosporales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158249_k127_1852005_0	391037.Sare_4168	8.807e-118	400.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria,4D8V1@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_1852005_5	1894.JOER01000016_gene5540	1.607e-34	149.0	COG1277@1|root,COG1277@2|Bacteria,2GKKP@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158249_k127_1852005_1	58123.JOFJ01000024_gene3460	6.536e-117	385.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4EIF9@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_1852005_3	1229780.BN381_80233	1.086e-83	297.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
SRR25158249_k127_1852005_2	234621.RER_33580	1.414e-106	351.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4FUIQ@85025|Nocardiaceae	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158249_k127_1869737_2	765420.OSCT_2335	7.47e-05	47.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,376RN@32061|Chloroflexia	32061|Chloroflexia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158249_k127_1869737_0	760568.Desku_1293	8.236e-68	250.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,260IY@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158249_k127_1869737_1	370438.PTH_2212	4.044e-32	132.0	COG2110@1|root,COG2755@1|root,COG2110@2|Bacteria,COG2755@2|Bacteria,1VDE2@1239|Firmicutes,24N6X@186801|Clostridia,262J2@186807|Peptococcaceae	186801|Clostridia	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158249_k127_1874516_2	1303518.CCALI_01542	1.244e-33	142.0	COG0497@1|root,COG0497@2|Bacteria	2|Bacteria	L	DNA recombination	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03631,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
SRR25158249_k127_1874516_1	552811.Dehly_0367	1.046e-42	175.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi,34CNH@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158249_k127_1874516_0	1128421.JAGA01000002_gene1553	5.743e-66	233.0	COG1189@1|root,COG1189@2|Bacteria,2NPHR@2323|unclassified Bacteria	2|Bacteria	J	FtsJ-like methyltransferase	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158249_k127_1877294_1	1382306.JNIM01000001_gene3777	1.59e-74	269.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158249_k127_1877294_0	1382356.JQMP01000003_gene2113	1.931e-105	346.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158249_k127_1885284_2	1123503.KB908059_gene239	6.61e-10	61.0	COG4496@1|root,COG4496@2|Bacteria,1N87R@1224|Proteobacteria,2UGB7@28211|Alphaproteobacteria,2KJ3H@204458|Caulobacterales	204458|Caulobacterales	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
SRR25158249_k127_1885284_1	661478.OP10G_4355	7.477e-50	187.0	COG0106@1|root,COG0106@2|Bacteria	2|Bacteria	E	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0033554,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0050896,GO:0051716,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0850,iSDY_1059.SDY_2217	His_biosynth
SRR25158249_k127_1885284_0	1303518.CCALI_02875	1.368e-137	452.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158249_k127_1886021_4	1122132.AQYH01000010_gene3770	3.296e-07	57.0	COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,2U7GQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4332)	MA20_15755	-	-	-	-	-	-	-	-	-	-	-	DUF4332
SRR25158249_k127_1886021_3	1479623.JHEL01000012_gene1888	1.223e-08	65.0	COG4478@1|root,COG4478@2|Bacteria,2IFW4@201174|Actinobacteria,4FS2J@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
SRR25158249_k127_1886021_2	309801.trd_1718	7.702e-44	179.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158249_k127_1886021_0	1210045.ALNP01000008_gene4596	9.601e-85	297.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria	201174|Actinobacteria	H	Molybdenum cofactor synthesis domain protein	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158249_k127_1886021_1	1121124.JNIX01000013_gene1547	2.528e-44	177.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2KGJZ@204458|Caulobacterales	204458|Caulobacterales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158249_k127_1888207_3	436229.JOEH01000004_gene124	1.246e-29	126.0	COG0640@1|root,COG0640@2|Bacteria,2GUG4@201174|Actinobacteria,2NIN4@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158249_k127_1888207_0	926550.CLDAP_40500	1.33e-67	243.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158249_k127_1888207_1	1121377.KB906402_gene3334	5.617e-61	237.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,Guanylate_cyc,NB-ARC,TPR_12
SRR25158249_k127_1888207_2	1394178.AWOO02000010_gene4222	1.357e-51	188.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4EPAK@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158249_k127_1888207_4	553973.CLOHYLEM_06986	0.0003341	44.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,220M1@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR25158249_k127_1888433_0	1137268.AZXF01000010_gene2751	8.237e-84	289.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4EHAT@85012|Streptosporangiales	201174|Actinobacteria	L	RecG wedge domain	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158249_k127_1888433_3	445972.ANACOL_00441	2.313e-27	128.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WJC4@541000|Ruminococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158249_k127_1888433_1	796942.HMPREF9623_00282	9.843e-44	177.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158249_k127_1888433_4	1382306.JNIM01000001_gene3738	5.236e-22	103.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1888433_5	1122609.AUGT01000022_gene617	1.465e-16	93.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4DQUU@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158249_k127_1888433_6	926561.KB900622_gene603	1.112e-14	80.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WBZP@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158249_k127_1888433_2	913865.DOT_3510	4.024e-33	137.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158249_k127_1894658_3	1071073.KI530537_gene1320	7.188e-22	99.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus	91061|Bacilli	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158249_k127_1894658_0	926569.ANT_12940	6.264e-70	257.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158249_k127_1894658_2	1089548.KI783301_gene2887	5.523e-35	145.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,3WFE2@539002|Bacillales incertae sedis	91061|Bacilli	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158249_k127_1894658_1	1123311.KB904470_gene1233	1.401e-59	210.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158249_k127_189621_1	383372.Rcas_2004	2.88e-63	233.0	COG2378@1|root,COG2378@2|Bacteria,2G6Z2@200795|Chloroflexi,375E1@32061|Chloroflexia	32061|Chloroflexia	K	Helix-turn-helix type 11 domain protein	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
SRR25158249_k127_189621_2	258594.RPA4208	9.597e-06	57.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,2UFSP@28211|Alphaproteobacteria,3JVHE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cysteine-rich secretory protein family	MA20_18185	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158249_k127_189621_0	330214.NIDE3049	3.236e-83	288.0	COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae	40117|Nitrospirae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158249_k127_190877_0	1382356.JQMP01000003_gene2146	3.647e-114	382.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SRR25158249_k127_190877_1	1437824.BN940_01611	6.522e-07	62.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria,3T3P4@506|Alcaligenaceae	28216|Betaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158249_k127_1927797_5	696747.NIES39_L00950	0.0003516	49.0	COG1950@1|root,COG1950@2|Bacteria,1G7RB@1117|Cyanobacteria,1HC6H@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158249_k127_1927797_3	394.NGR_c00790	6.056e-17	90.0	COG4803@1|root,COG4803@2|Bacteria,1RC5W@1224|Proteobacteria,2U6VR@28211|Alphaproteobacteria,4BC8Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158249_k127_1927797_2	1196324.A374_04909	5.915e-28	117.0	COG1670@1|root,COG1670@2|Bacteria,1UWX1@1239|Firmicutes,4HT0S@91061|Bacilli	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_1927797_4	1246995.AFR_27135	3.378e-11	70.0	COG1670@1|root,COG1670@2|Bacteria,2IIWF@201174|Actinobacteria,4DJ5S@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128,2.3.1.82	ko:K00663,ko:K03790	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158249_k127_1927797_0	671143.DAMO_2637	9.514e-90	316.0	COG0402@1|root,COG0402@2|Bacteria,2NPE6@2323|unclassified Bacteria	2|Bacteria	F	Amidohydrolase family	guaD	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3170,iECED1_1282.ECED1_3343,iECIAI1_1343.ECIAI1_3003,iECSE_1348.ECSE_3147	Amidohydro_1
SRR25158249_k127_1927797_1	1463856.JOHY01000034_gene2355	1.819e-33	138.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158249_k127_1936787_0	868864.Dester_1396	5.848e-40	151.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158249_k127_1936787_2	1121106.JQKB01000059_gene4749	2.868e-21	108.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_1936787_1	370438.PTH_2747	5.618e-29	121.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,25ZZ9@186807|Peptococcaceae	186801|Clostridia	D	TIGRFAM Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158249_k127_1943920_1	1382306.JNIM01000001_gene684	5.3e-31	124.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158249_k127_1943920_0	1382306.JNIM01000001_gene2555	1.747e-123	409.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158249_k127_1945547_0	234267.Acid_5780	2.887e-74	275.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
SRR25158249_k127_1945547_1	457429.ABJI02000796_gene4439	4.12e-11	76.0	COG2909@1|root,COG2909@2|Bacteria,2ING5@201174|Actinobacteria	201174|Actinobacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1945847_1	264732.Moth_0828	1.955e-07	62.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42FXX@68295|Thermoanaerobacterales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9
SRR25158249_k127_1945847_0	552398.HMPREF0866_01412	3.535e-61	218.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3WIDV@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_19509_2	926569.ANT_05580	2.258e-41	159.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158249_k127_19509_3	1234364.AMSF01000032_gene3383	2.485e-18	95.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,1S9KM@1236|Gammaproteobacteria,1X7M1@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158249_k127_19509_1	204669.Acid345_1271	4.891e-124	416.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158249_k127_19509_0	204669.Acid345_1270	5.38e-150	480.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158249_k127_1951157_0	309799.DICTH_1915	5.699e-73	265.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldE2	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158249_k127_1951157_1	309799.DICTH_1914	5.82e-43	159.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158249_k127_1952985_2	1340493.JNIF01000003_gene4562	4.175e-40	149.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158249_k127_1952985_0	1128421.JAGA01000002_gene1557	2.325e-67	236.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158249_k127_1952985_3	469371.Tbis_0248	1.06e-05	58.0	2E8P5@1|root,3330B@2|Bacteria,2GRP1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1952985_1	525909.Afer_1990	1.79e-50	195.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CNDB@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158249_k127_1952985_4	1120949.KB903321_gene2682	0.0001137	51.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DAXE@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158249_k127_1953770_0	484770.UFO1_4407	9.006e-78	270.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,4H2FM@909932|Negativicutes	909932|Negativicutes	E	Glutamate formiminotransferase	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158249_k127_1953770_1	477641.MODMU_4291	2.348e-65	231.0	COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria,4EXF3@85013|Frankiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158249_k127_1954370_1	1476583.DEIPH_ctg032orf0002	5.419e-09	57.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_1954370_0	358823.DF19_20485	5.731e-72	248.0	COG1063@1|root,COG1063@2|Bacteria,2GNXK@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158249_k127_1956420_0	1242864.D187_000069	6.464e-69	248.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YZXT@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158249_k127_1956420_1	311424.DhcVS_307	7.591e-07	59.0	2A4G3@1|root,30T26@2|Bacteria,2GAY4@200795|Chloroflexi,34DJS@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_1963486_2	477974.Daud_1638	2.273e-55	212.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158249_k127_1963486_1	1128421.JAGA01000003_gene3523	1.01e-63	246.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158249_k127_1963486_0	357808.RoseRS_2419	1.429e-92	320.0	COG1131@1|root,COG1131@2|Bacteria,2GAQH@200795|Chloroflexi,3753M@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158249_k127_1963486_3	697281.Mahau_1544	2.618e-29	129.0	COG1668@1|root,COG1668@2|Bacteria,1UIA3@1239|Firmicutes,25EF1@186801|Clostridia	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158249_k127_1984552_0	1341151.ASZU01000003_gene2589	1.171e-80	293.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,27AXW@186824|Thermoactinomycetaceae	91061|Bacilli	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
SRR25158249_k127_1984552_1	911045.PSE_2196	4.19e-58	213.0	COG0765@1|root,COG0765@2|Bacteria,1QXFC@1224|Proteobacteria,2TV20@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158249_k127_1984552_2	321327.CYA_0685	7.608e-55	203.0	COG0834@1|root,COG0834@2|Bacteria,1GJVF@1117|Cyanobacteria,1H1U5@1129|Synechococcus	1117|Cyanobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRR25158249_k127_1990753_1	1254432.SCE1572_22460	4.031e-130	434.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2YU99@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158249_k127_1990753_2	643648.Slip_2161	1.311e-46	180.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,42JXR@68298|Syntrophomonadaceae	186801|Clostridia	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158249_k127_1990753_0	316274.Haur_4449	1.03e-181	586.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,3751J@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158249_k127_2002424_0	525904.Tter_1187	4.468e-60	216.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2NP05@2323|unclassified Bacteria	2|Bacteria	H	Methylenetetrahydrofolate reductase	yitJ	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
SRR25158249_k127_2002424_1	1445613.JALM01000009_gene898	9.758e-47	177.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4DYM2@85010|Pseudonocardiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158249_k127_2004629_3	485913.Krac_2861	1.812e-16	89.0	COG3884@1|root,COG3884@2|Bacteria	2|Bacteria	I	thiolester hydrolase activity	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
SRR25158249_k127_2004629_0	287986.DV20_23450	5.345e-153	507.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4E1ST@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158249_k127_2004629_2	552811.Dehly_1111	5.846e-73	266.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,34CT3@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HisKA_7TM
SRR25158249_k127_2004629_1	290397.Adeh_3709	5.016e-77	273.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_2015433_1	926550.CLDAP_02330	6.872e-112	370.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158249_k127_2015433_0	103733.JNYO01000020_gene1908	2.829e-157	508.0	COG1231@1|root,COG1231@2|Bacteria,2GMV0@201174|Actinobacteria,4DZ53@85010|Pseudonocardiales	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158249_k127_2015846_0	1313172.YM304_20690	3.263e-24	104.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158249_k127_2015846_1	926560.KE387023_gene1206	4.513e-15	81.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158249_k127_2022964_1	471852.Tcur_0300	2.647e-60	212.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4EGDA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158249_k127_2022964_0	1173028.ANKO01000106_gene363	8.546e-96	329.0	COG0150@1|root,COG0150@2|Bacteria,1G1WY@1117|Cyanobacteria,1H8GW@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158249_k127_2023922_1	675635.Psed_0413	1.536e-31	132.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158249_k127_2023922_0	1535287.JP74_09390	1.804e-107	359.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria,3N7PV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF58	MA20_44650	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158249_k127_2023922_2	1283283.ATXA01000008_gene3000	0.0004857	43.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4ERGM@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158249_k127_2042424_1	383372.Rcas_0979	2.749e-73	254.0	COG4770@1|root,COG4770@2|Bacteria,2GBIE@200795|Chloroflexi,374S0@32061|Chloroflexia	32061|Chloroflexia	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158249_k127_2042424_0	485913.Krac_12092	5.656e-228	718.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158249_k127_2042424_2	1032480.MLP_17510	3.255e-68	243.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DP0V@85009|Propionibacteriales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158249_k127_2042796_1	935948.KE386494_gene514	6.722e-74	271.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,42FRP@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM penicillin-binding protein transpeptidase	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158249_k127_2042796_0	479434.Sthe_1162	6.378e-102	349.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,27Y4C@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158249_k127_2042796_2	485913.Krac_11253	9.469e-22	104.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158249_k127_2042796_3	383372.Rcas_2061	2.589e-20	102.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158249_k127_2043401_0	1382306.JNIM01000001_gene2652	5.923e-54	201.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158249_k127_2043401_2	1449346.JQMO01000003_gene5757	2.857e-23	106.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,2M3I2@2063|Kitasatospora	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158249_k127_2043401_1	1120948.KB903240_gene3977	1.357e-51	188.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4DZ8F@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
SRR25158249_k127_2045976_1	1121035.AUCH01000014_gene2415	1.339e-12	79.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,2KV5D@206389|Rhodocyclales	206389|Rhodocyclales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
SRR25158249_k127_2045976_0	1298863.AUEP01000014_gene1605	1.557e-38	155.0	COG2335@1|root,COG2335@2|Bacteria,2IHKV@201174|Actinobacteria,4DUY2@85009|Propionibacteriales	201174|Actinobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158249_k127_2052746_1	1278073.MYSTI_02672	4.512e-117	401.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2YX1N@29|Myxococcales	28221|Deltaproteobacteria	U	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158249_k127_2052746_6	266940.Krad_3531	1.071e-20	108.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158249_k127_2052746_4	1869.MB27_01265	1.444e-44	178.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yflN	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158249_k127_2052746_5	246200.SPO3350	9.167e-21	95.0	COG3795@1|root,COG3795@2|Bacteria,1RJJG@1224|Proteobacteria,2UCR2@28211|Alphaproteobacteria,4NCMU@97050|Ruegeria	28211|Alphaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158249_k127_2052746_0	926569.ANT_13670	6.433e-228	718.0	COG1069@1|root,COG1069@2|Bacteria,2G8AT@200795|Chloroflexi	200795|Chloroflexi	C	FGGY family of carbohydrate kinases, N-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_2052746_3	935845.JADQ01000001_gene1128	1.662e-79	283.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,26SKE@186822|Paenibacillaceae	91061|Bacilli	G	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source	araD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158249_k127_2052746_2	479432.Sros_6217	1.825e-110	361.0	COG2160@1|root,COG2160@2|Bacteria,2GJNB@201174|Actinobacteria,4EGQ7@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
SRR25158249_k127_2060180_2	1297742.A176_05550	4.207e-06	49.0	COG0251@1|root,COG0251@2|Bacteria,1RES6@1224|Proteobacteria,435VN@68525|delta/epsilon subdivisions,2X0B9@28221|Deltaproteobacteria,2Z1FV@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158249_k127_2060180_1	477228.YO5_20161	6.674e-29	129.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1RZYJ@1236|Gammaproteobacteria,1Z1P4@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158249_k127_2060180_0	1382356.JQMP01000004_gene581	3.186e-48	181.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158249_k127_2066441_3	1123288.SOV_1c10020	1.441e-35	141.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H3KI@909932|Negativicutes	909932|Negativicutes	M	Belongs to the EPSP synthase family. MurA subfamily	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158249_k127_2066441_0	1382356.JQMP01000003_gene1994	1.528e-139	451.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158249_k127_2066441_2	525904.Tter_0400	8.891e-37	148.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158249_k127_2066441_1	1521187.JPIM01000017_gene348	4.191e-58	223.0	COG0392@1|root,COG0392@2|Bacteria,2G6NX@200795|Chloroflexi,3765H@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158249_k127_2068053_3	469383.Cwoe_3809	1.592e-43	162.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CT75@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158249_k127_2068053_7	512565.AMIS_59390	2e-14	81.0	arCOG05230@1|root,33GXI@2|Bacteria,2ICB0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2068053_2	525904.Tter_0762	5.314e-50	194.0	COG0177@1|root,COG0177@2|Bacteria,2NP8N@2323|unclassified Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158249_k127_2068053_4	1121472.AQWN01000007_gene1099	4.893e-33	134.0	COG3744@1|root,COG3744@2|Bacteria,1V6HT@1239|Firmicutes,24JWY@186801|Clostridia,265AS@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158249_k127_2068053_6	760568.Desku_0561	2.951e-15	79.0	COG4118@1|root,COG4118@2|Bacteria,1VHN9@1239|Firmicutes,24SB0@186801|Clostridia,265UK@186807|Peptococcaceae	186801|Clostridia	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158249_k127_2068053_1	401526.TcarDRAFT_0360	2.984e-81	294.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4H2JX@909932|Negativicutes	909932|Negativicutes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158249_k127_2068053_0	1128421.JAGA01000003_gene2709	3.416e-138	469.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
SRR25158249_k127_2068053_5	644282.Deba_1058	2.092e-23	107.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR25158249_k127_2072424_0	1120950.KB892771_gene1287	1.079e-71	249.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4DPZ7@85009|Propionibacteriales	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRR25158249_k127_2072424_3	675635.Psed_0313	3.504e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4E4PD@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158249_k127_2072424_1	469371.Tbis_1015	2.242e-51	191.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4E53R@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158249_k127_2072424_4	1120934.KB894423_gene2695	5.339e-44	162.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4E4JT@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158249_k127_2072424_2	1041522.MCOL_V208365	2.677e-51	192.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,234JA@1762|Mycobacteriaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158249_k127_2072424_5	1283299.AUKG01000001_gene1526	8.284e-33	131.0	COG0454@1|root,COG0456@2|Bacteria,2IAC7@201174|Actinobacteria,4CSRP@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SRR25158249_k127_208792_0	1121451.DESAM_22960	4.496e-28	127.0	COG0697@1|root,COG0697@2|Bacteria,1NS7A@1224|Proteobacteria,42MCJ@68525|delta/epsilon subdivisions,2WKQ4@28221|Deltaproteobacteria,2M94E@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158249_k127_2091767_0	1121468.AUBR01000002_gene638	4.013e-106	361.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
SRR25158249_k127_2100619_2	561175.KB894095_gene2266	4.475e-09	63.0	COG2215@1|root,COG2215@2|Bacteria,2H0S3@201174|Actinobacteria,4EG4B@85012|Streptosporangiales	201174|Actinobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRR25158249_k127_2100619_0	448385.sce7282	1.018e-32	145.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce7282|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2100619_1	543632.JOJL01000019_gene10072	2.45e-31	136.0	28KIP@1|root,2ZA3U@2|Bacteria,2I3VC@201174|Actinobacteria,4DDVQ@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158249_k127_2104888_0	1123023.JIAI01000020_gene2106	1.37e-211	672.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158249_k127_2104888_1	1123023.JIAI01000020_gene2107	7.369e-127	428.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria,4DXFK@85010|Pseudonocardiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
SRR25158249_k127_2104888_2	886293.Sinac_4483	6.969e-82	291.0	COG1526@1|root,COG1526@2|Bacteria,2IZ61@203682|Planctomycetes	203682|Planctomycetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158249_k127_2104888_3	1121324.CLIT_2c03230	2.905e-56	206.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SRR25158249_k127_2104888_4	33876.JNXY01000020_gene4470	2.203e-07	60.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4DJQN@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158249_k127_2105254_2	290397.Adeh_1650	7.719e-17	88.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2YVFW@29|Myxococcales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158249_k127_2105254_1	572477.Alvin_1890	4.184e-23	108.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1WYUG@135613|Chromatiales	135613|Chromatiales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158249_k127_2105254_3	1089552.KI911559_gene2370	1.036e-10	71.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,2JT9S@204441|Rhodospirillales	204441|Rhodospirillales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158249_k127_2105254_4	1151126.AQYI01000007_gene2163	3.141e-06	53.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria,4FPDP@85023|Microbacteriaceae	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158249_k127_2105254_0	485913.Krac_8684	5.331e-27	115.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158249_k127_2113763_0	765420.OSCT_2063	7.295e-87	304.0	COG1169@1|root,COG1169@2|Bacteria,2G5RQ@200795|Chloroflexi,375P4@32061|Chloroflexia	32061|Chloroflexia	HQ	TIGRFAM isochorismate synthase	-	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158249_k127_2113763_1	479434.Sthe_3024	4.707e-85	297.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158249_k127_2132459_2	1133850.SHJG_2407	3.975e-60	220.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria	201174|Actinobacteria	O	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158249_k127_2132459_1	1385519.N801_08575	6.103e-67	235.0	28RC2@1|root,2ZDRH@2|Bacteria,2GNI9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SRR25158249_k127_2132459_0	345341.KUTG_07888	1.383e-221	700.0	COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria,4E0BB@85010|Pseudonocardiales	201174|Actinobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158249_k127_2132459_4	489825.LYNGBM3L_04030	5.309e-23	104.0	2DB76@1|root,2Z7JZ@2|Bacteria,1GRAE@1117|Cyanobacteria,1HIB6@1150|Oscillatoriales	1117|Cyanobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR25158249_k127_2132459_3	479431.Namu_1901	4.53e-56	201.0	arCOG11412@1|root,31S84@2|Bacteria,2IHRW@201174|Actinobacteria,4ET6M@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2132459_5	1463825.JNXC01000023_gene4949	1.04e-17	83.0	arCOG11411@1|root,33A8Q@2|Bacteria,2GRHE@201174|Actinobacteria,4E81R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2144073_1	35754.JNYJ01000038_gene5070	1.169e-39	155.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,4DCCG@85008|Micromonosporales	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158249_k127_2144073_0	292459.STH3193	1.903e-268	834.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158249_k127_2150366_0	1280949.HAD_05105	3.826e-76	280.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158249_k127_2150366_1	1032480.MLP_35330	4.902e-33	141.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria,4DT6M@85009|Propionibacteriales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158249_k127_2167092_1	471853.Bcav_1557	1.013e-15	92.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158249_k127_2167092_0	1122611.KB903948_gene6718	2.205e-112	401.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158249_k127_216938_0	316274.Haur_3105	6.135e-118	393.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	scpD	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
SRR25158249_k127_216938_1	1242864.D187_005844	1.149e-16	87.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YYMR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158249_k127_2181344_0	211165.AJLN01000037_gene1958	6.622e-197	629.0	COG1866@1|root,COG1866@2|Bacteria,1G1KI@1117|Cyanobacteria,1JJE3@1189|Stigonemataceae	1117|Cyanobacteria	C	Phosphoenolpyruvate carboxykinase	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158249_k127_2181344_1	644282.Deba_1366	2.238e-120	420.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158249_k127_2204080_1	926550.CLDAP_25340	1.557e-31	140.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158249_k127_2204080_2	574087.Acear_1595	9.095e-27	117.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WAT9@53433|Halanaerobiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158249_k127_2204080_0	1121428.DESHY_80091___1	2.542e-107	356.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158249_k127_2204143_0	1265313.HRUBRA_01008	2.244e-41	170.0	COG1957@1|root,COG5042@1|root,COG1957@2|Bacteria,COG5042@2|Bacteria,1MUIW@1224|Proteobacteria,1RSCY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the IUNH family	rihA	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598	IU_nuc_hydro
SRR25158249_k127_2204143_1	1128421.JAGA01000002_gene1198	2.763e-13	70.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K15945	ko01057,ko01130,map01057,map01130	-	R09330	RC00046	ko00000,ko00001	-	-	-	SnoaL,SnoaL_2
SRR25158249_k127_220785_3	1123226.KB899282_gene3032	2.801e-16	93.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,26VDG@186822|Paenibacillaceae	91061|Bacilli	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158249_k127_220785_1	1048339.KB913029_gene1655	2.317e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4ESTA@85013|Frankiales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_220785_6	1235802.C823_02934	0.0001347	52.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,24QWH@186801|Clostridia,25XRF@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
SRR25158249_k127_220785_2	552398.HMPREF0866_02379	4.197e-21	100.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WIW4@541000|Ruminococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_220785_4	316274.Haur_0977	6.651e-15	88.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158249_k127_220785_0	1128421.JAGA01000003_gene2742	3.533e-59	213.0	COG1309@1|root,COG1309@2|Bacteria,2NRTD@2323|unclassified Bacteria	2|Bacteria	K	YsiA-like protein, C-terminal region	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TetR_C_4,TetR_N
SRR25158249_k127_220785_5	479434.Sthe_3025	4.334e-12	75.0	COG1169@1|root,COG1169@2|Bacteria,2GADW@200795|Chloroflexi,27Y2P@189775|Thermomicrobia	189775|Thermomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158249_k127_2216472_2	1521187.JPIM01000025_gene1131	0.0002825	54.0	COG3103@1|root,COG3103@2|Bacteria,2G7IJ@200795|Chloroflexi,377Y8@32061|Chloroflexia	32061|Chloroflexia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158249_k127_2216472_1	1196323.ALKF01000197_gene2249	2.605e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,4IQ93@91061|Bacilli,27695@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_2216472_0	316274.Haur_4470	1.389e-21	104.0	COG3404@1|root,COG3404@2|Bacteria,2G70J@200795|Chloroflexi,375J7@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SRR25158249_k127_222474_1	1174528.JH992893_gene5976	1.477e-35	140.0	COG1023@1|root,COG1023@2|Bacteria,1G07T@1117|Cyanobacteria,1JMU3@1189|Stigonemataceae	1117|Cyanobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158249_k127_222474_0	926560.KE387023_gene2328	5.877e-126	410.0	COG3458@1|root,COG3458@2|Bacteria,1WKVT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
SRR25158249_k127_2241633_1	1210045.ALNP01000002_gene3975	1.593e-10	73.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,Guanylate_cyc,Trans_reg_C
SRR25158249_k127_2241633_2	35754.JNYJ01000003_gene6404	4.508e-07	61.0	2F3MR@1|root,33WEW@2|Bacteria,2IMZP@201174|Actinobacteria,4DE76@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2241633_0	994479.GL877878_gene2041	3.777e-120	400.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158249_k127_2255800_4	743718.Isova_2381	8.757e-24	102.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4F5BW@85017|Promicromonosporaceae	201174|Actinobacteria	P	Adenylylsulphate kinase	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158249_k127_2255800_3	1214101.BN159_5700	3.469e-70	258.0	290E5@1|root,2ZN3G@2|Bacteria,2IH3T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2255800_0	285535.JOEY01000013_gene4600	1.15e-77	278.0	290E5@1|root,2ZN3G@2|Bacteria,2IH3T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2255800_2	1137269.AZWL01000021_gene3345	5.405e-73	262.0	2DRBV@1|root,33B5H@2|Bacteria,2I4C9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2255800_1	1463881.KL591006_gene2448	9.957e-75	266.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158249_k127_2255800_5	1448389.BAVQ01000013_gene4022	1.224e-21	104.0	2BF47@1|root,328WE@2|Bacteria,2IM74@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
SRR25158249_k127_2255800_6	1423807.BACO01000019_gene621	4.605e-09	60.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae	91061|Bacilli	O	assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158249_k127_2257294_5	456442.Mboo_0642	7.784e-38	154.0	arCOG08211@1|root,arCOG08211@2157|Archaea,2XW85@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2257294_9	469383.Cwoe_2966	1.757e-09	61.0	COG4118@1|root,COG4118@2|Bacteria,2HRUG@201174|Actinobacteria,4CTXW@84995|Rubrobacteria	84995|Rubrobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158249_k127_2257294_10	1123389.ATXJ01000032_gene1672	4.741e-08	59.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158249_k127_2257294_6	1463825.JNXC01000001_gene5419	1.486e-37	146.0	2CBYE@1|root,32RUB@2|Bacteria,2IM4Q@201174|Actinobacteria,4E5ER@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2257294_7	1449976.KALB_2203	4.783e-28	114.0	COG1476@1|root,COG1476@2|Bacteria,2GQIU@201174|Actinobacteria,4E5YC@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRR25158249_k127_2257294_3	219305.MCAG_00811	9.841e-58	207.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria,4DERE@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_2257294_2	1120949.KB903311_gene793	1.145e-91	318.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158249_k127_2257294_8	1403313.AXBR01000010_gene1079	2.932e-19	96.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZIEP@1386|Bacillus	91061|Bacilli	I	COG0671 Membrane-associated phospholipid phosphatase	pgpB3	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158249_k127_2257294_4	882083.SacmaDRAFT_2080	2.348e-57	215.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF2505
SRR25158249_k127_2257294_0	1502851.FG93_01170	4.462e-116	377.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2U0RG@28211|Alphaproteobacteria,3JUIU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158249_k127_2257294_1	66874.JOFS01000035_gene607	5.209e-115	392.0	COG4292@1|root,COG4292@2|Bacteria,2IC48@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158249_k127_2274770_1	1172179.AUKV01000001_gene1337	1.477e-77	269.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158249_k127_2274770_0	158787.BSCA_2456	1.533e-206	669.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4D0EY@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 36 C-terminal domain	agaB3	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
SRR25158249_k127_2275131_2	1128421.JAGA01000002_gene272	4.394e-31	134.0	COG0340@1|root,COG0340@2|Bacteria,2NPG2@2323|unclassified Bacteria	2|Bacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158249_k127_2275131_0	311424.DhcVS_1515	2.32e-131	443.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,34CW8@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
SRR25158249_k127_2275131_3	485918.Cpin_4776	0.0003014	51.0	COG1396@1|root,COG1396@2|Bacteria,4NU6M@976|Bacteroidetes,1IYV9@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158249_k127_2275131_1	1120950.KB892742_gene3009	4.532e-67	239.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria,4DQY9@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158249_k127_2285813_0	926550.CLDAP_24290	9.2e-102	353.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158249_k127_2291886_0	309801.trd_0619	1.638e-44	170.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158249_k127_2291886_1	1379698.RBG1_1C00001G0503	5.481e-14	84.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
SRR25158249_k127_2326254_1	316274.Haur_4100	1.034e-99	357.0	COG0044@1|root,COG0044@2|Bacteria,2G640@200795|Chloroflexi,3755Y@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158249_k127_2326254_0	357808.RoseRS_2863	8.779e-106	357.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,376MF@32061|Chloroflexia	32061|Chloroflexia	F	PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158249_k127_2326254_2	526227.Mesil_1879	3.376e-70	243.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158249_k127_2326254_4	411467.BACCAP_02400	5.197e-05	56.0	COG5662@1|root,COG5662@2|Bacteria,1VHF3@1239|Firmicutes,24SVU@186801|Clostridia,269PP@186813|unclassified Clostridiales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158249_k127_2326254_3	479434.Sthe_2174	1.464e-19	97.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_2329377_0	1523503.JPMY01000045_gene83	2.555e-55	216.0	COG0747@1|root,COG3210@1|root,COG4932@1|root,COG0747@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,1T32K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	HemY domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin_3,Calx-beta,DUF4347,He_PIG,OmpA_membrane
SRR25158249_k127_2329377_1	626887.J057_17665	1.83e-10	74.0	COG3637@1|root,COG4547@1|root,COG4932@1|root,COG3637@2|Bacteria,COG4547@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,1T4AQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SRR25158249_k127_23306_0	326427.Cagg_2663	4.645e-28	113.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158249_k127_2337925_3	1006000.GKAS_02144	0.0002789	50.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044424,GO:0044444,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
SRR25158249_k127_2337925_0	290397.Adeh_2624	1.118e-73	257.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158249_k127_2337925_2	1120944.JONS01000001_gene2032	0.0001244	55.0	COG0438@1|root,COG0438@2|Bacteria,2HF09@201174|Actinobacteria,4D40P@85005|Actinomycetales	201174|Actinobacteria	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158249_k127_2337925_1	1286171.EAL2_c07660	5.547e-49	193.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,25VD7@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158249_k127_2338104_0	1313172.YM304_30950	1.455e-177	563.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4CMVZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158249_k127_2338104_2	1343740.M271_12685	2.071e-25	113.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158249_k127_2338104_1	1385521.N803_02155	3.01e-32	141.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158249_k127_2346515_0	1128421.JAGA01000002_gene1211	1.234e-115	381.0	COG0714@1|root,COG0714@2|Bacteria,2NQNN@2323|unclassified Bacteria	2|Bacteria	S	AAA domain (dynein-related subfamily)	coxD	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158249_k127_2346515_1	479434.Sthe_1402	2.056e-15	86.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia	189775|Thermomicrobia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158249_k127_2360980_0	420324.KI912037_gene2409	3.532e-39	148.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,1JS1S@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
SRR25158249_k127_2360980_2	331113.SNE_A18580	5.891e-19	92.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
SRR25158249_k127_2368832_1	1210884.HG799466_gene12571	1.325e-66	231.0	COG1053@1|root,COG1053@2|Bacteria,2IX3A@203682|Planctomycetes	203682|Planctomycetes	C	succinate dehydrogenase or fumarate reductase, flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158249_k127_2368832_2	1267534.KB906759_gene1791	6.117e-57	220.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2368832_0	644966.Tmar_1163	5.059e-148	474.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WD6G@538999|Clostridiales incertae sedis	186801|Clostridia	CE	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158249_k127_2398909_1	313606.M23134_00969	6.35e-23	108.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158249_k127_2398909_0	1283299.AUKG01000002_gene5269	3.83e-40	171.0	COG2199@1|root,COG3706@2|Bacteria,2HFS4@201174|Actinobacteria,4CRDM@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158249_k127_2400048_0	316274.Haur_2119	2.538e-135	439.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,376BP@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158249_k127_2400048_1	316274.Haur_2118	4.921e-105	351.0	COG1172@1|root,COG1172@2|Bacteria,2G6A4@200795|Chloroflexi,377ZT@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158249_k127_2400048_2	1122918.KB907252_gene2868	6.286e-93	331.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,4HEDJ@91061|Bacilli,26QGR@186822|Paenibacillaceae	91061|Bacilli	G	Membrane component of a	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158249_k127_2400048_3	1463821.JOGR01000007_gene353	2.093e-30	136.0	COG2160@1|root,COG2160@2|Bacteria,2GJNB@201174|Actinobacteria,4EYTE@85014|Glycomycetales	201174|Actinobacteria	G	L-arabinose isomerase	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
SRR25158249_k127_2406513_0	485913.Krac_9213	4.006e-88	310.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158249_k127_2406513_1	1280686.AUKE01000011_gene1689	2.35e-30	122.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,4BZNY@830|Butyrivibrio	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158249_k127_2408963_1	518766.Rmar_1671	1.253e-121	398.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,1FJSZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158249_k127_2408963_4	298655.KI912266_gene5433	1.433e-15	88.0	COG0454@1|root,COG0456@2|Bacteria,2GVT5@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158249_k127_2408963_0	1386089.N865_16750	9.626e-132	436.0	COG3191@1|root,COG3191@2|Bacteria,2H89D@201174|Actinobacteria,4FGPH@85021|Intrasporangiaceae	201174|Actinobacteria	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158249_k127_2408963_2	1123242.JH636435_gene2205	7.976e-95	344.0	COG0147@1|root,COG0147@2|Bacteria,2IXEN@203682|Planctomycetes	203682|Planctomycetes	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158249_k127_2408963_3	1089551.KE386572_gene51	2.535e-47	183.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2U9QU@28211|Alphaproteobacteria,4BS4N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158249_k127_2409365_1	370438.PTH_1210	6.656e-36	147.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,260PK@186807|Peptococcaceae	186801|Clostridia	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158249_k127_2409365_0	324602.Caur_0610	2.374e-65	235.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi,375E5@32061|Chloroflexia	32061|Chloroflexia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158249_k127_2418349_0	1120950.KB892707_gene4945	1.814e-61	224.0	COG1123@1|root,COG4172@2|Bacteria,2H2BQ@201174|Actinobacteria,4DWHF@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158249_k127_2418349_2	1246995.AFR_08050	2.534e-44	169.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4D9S6@85008|Micromonosporales	201174|Actinobacteria	S	ABC-type cobalt transport system, permease component	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
SRR25158249_k127_2418349_1	1313172.YM304_33770	1.737e-59	220.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158249_k127_2418349_3	477641.MODMU_1556	5.787e-24	106.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158249_k127_2420762_1	1380356.JNIK01000001_gene2211	1.58e-25	122.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4ES7C@85013|Frankiales	201174|Actinobacteria	S	ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158249_k127_2420762_0	457425.XNR_4370	1.501e-26	119.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158249_k127_2424749_1	404589.Anae109_1137	3.815e-06	50.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158249_k127_2424749_0	243231.GSU0686	1.388e-96	331.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158249_k127_24364_0	105420.BBPO01000031_gene6590	6.091e-65	232.0	COG0789@1|root,COG0789@2|Bacteria,2IC98@201174|Actinobacteria,2NGH2@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158249_k127_24364_1	485913.Krac_6694	2.424e-49	189.0	COG2141@1|root,COG2141@2|Bacteria,2G7V7@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_2462951_4	1394178.AWOO02000021_gene7297	6.023e-07	54.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158249_k127_2462951_2	1380356.JNIK01000015_gene2499	6.05e-15	86.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158249_k127_2462951_0	909663.KI867150_gene2803	6.94e-246	791.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MR2C@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158249_k127_2462951_1	290399.Arth_0897	7.594e-57	213.0	COG0662@1|root,COG0662@2|Bacteria,2IKT6@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158249_k127_2462951_3	1150864.MILUP08_41973	1.422e-07	54.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4DIRB@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_2465622_1	448385.sce3024	8.996e-26	110.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158249_k127_2465622_0	263358.VAB18032_24655	1.156e-149	487.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4D9XT@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158249_k127_2466813_0	562970.Btus_1243	1.158e-63	225.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158249_k127_2466813_2	1304865.JAGF01000001_gene435	3.16e-05	56.0	2DPD0@1|root,331J4@2|Bacteria,2IFZU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2466813_1	882083.SacmaDRAFT_1556	6.491e-17	91.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4E1IN@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158249_k127_2470525_1	378806.STAUR_4811	1.951e-30	122.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2YX5K@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158249_k127_2470525_0	1345023.M467_15135	5.479e-123	409.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3WEAV@539002|Bacillales incertae sedis	91061|Bacilli	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158249_k127_247222_10	1206725.BAFU01000247_gene2562	0.000122	53.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4FWXB@85025|Nocardiaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158249_k127_247222_2	1463885.KL578354_gene8815	2.978e-69	263.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_247222_4	644966.Tmar_1235	1.305e-54	212.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,3WDKV@538999|Clostridiales incertae sedis	186801|Clostridia	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158249_k127_247222_3	526226.Gbro_3585	3.078e-55	200.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4GE40@85026|Gordoniaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158249_k127_247222_7	1121015.N789_09825	1.588e-30	128.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1X701@135614|Xanthomonadales	135614|Xanthomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158249_k127_247222_11	1499968.TCA2_2790	0.0009897	48.0	COG1396@1|root,COG1396@2|Bacteria,1UYX5@1239|Firmicutes,4HF70@91061|Bacilli,26QGI@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K20342,ko:K20391	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3
SRR25158249_k127_247222_9	1121272.KB903250_gene2773	4.657e-10	72.0	COG1396@1|root,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria,4DDKY@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8
SRR25158249_k127_247222_1	357808.RoseRS_1948	6.086e-74	280.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,374XI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158249_k127_247222_5	1226325.HMPREF1548_02544	4.609e-54	206.0	COG1470@1|root,COG1470@2|Bacteria,1TZ9A@1239|Firmicutes,24C4A@186801|Clostridia	186801|Clostridia	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
SRR25158249_k127_247222_0	1209989.TepiRe1_2708	2.107e-83	306.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,42ENV@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
SRR25158249_k127_247222_6	1226325.HMPREF1548_02542	1.981e-52	200.0	COG1277@1|root,COG1277@2|Bacteria,1TQM9@1239|Firmicutes,249MZ@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158249_k127_247222_8	1151118.KB895792_gene1977	7.355e-12	74.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,1W8AY@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158249_k127_2487456_3	1396141.BATP01000059_gene2444	7.889e-13	75.0	2FF51@1|root,34735@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2487456_0	1121946.AUAX01000022_gene3879	1.372e-117	395.0	COG3325@1|root,COG3325@2|Bacteria,2I2ZC@201174|Actinobacteria,4DBW0@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolases family 18	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_4_9,Glyco_hydro_18
SRR25158249_k127_2487456_2	1121272.KB903250_gene2722	1.379e-18	96.0	2E4RI@1|root,32ZK2@2|Bacteria,2HWWC@201174|Actinobacteria,4DKJ2@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2487456_1	1155718.KB891962_gene199	3.657e-31	128.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria	201174|Actinobacteria	S	deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_2487456_4	1122622.ATWJ01000002_gene800	3.441e-10	64.0	COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158249_k127_2504356_1	398580.Dshi_0830	5.648e-33	136.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2TSBX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158249_k127_2504356_0	485913.Krac_12095	1.014e-68	247.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158249_k127_2506409_2	1306174.JODP01000008_gene2840	4.321e-16	93.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria	201174|Actinobacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158249_k127_2506409_1	1146883.BLASA_1727	2.079e-26	126.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4ESP8@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR25158249_k127_2506409_0	1121924.ATWH01000002_gene3774	2.367e-80	291.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria,4FQMK@85023|Microbacteriaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158249_k127_2568610_0	448385.sce7448	3.254e-73	254.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria,2YWGV@29|Myxococcales	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158249_k127_2568610_1	1313172.YM304_17800	1.012e-24	113.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158249_k127_2582012_2	469383.Cwoe_5333	2.76e-29	130.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4CRCB@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_2582012_0	1382306.JNIM01000001_gene4190	1.644e-91	325.0	COG0863@1|root,COG0863@2|Bacteria,2G650@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158249_k127_2582012_1	1382356.JQMP01000003_gene2461	3.007e-67	243.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158249_k127_2584292_1	215803.DB30_8503	1.598e-78	271.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2YXMX@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
SRR25158249_k127_2584292_0	477641.MODMU_3675	9.503e-107	356.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4EWJ1@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158249_k127_2584292_2	1457250.BBMO01000002_gene2647	9.445e-33	143.0	arCOG12670@1|root,arCOG12670@2157|Archaea,2XXAX@28890|Euryarchaeota,23VWQ@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2586302_2	1232410.KI421426_gene1434	1.471e-42	169.0	COG0642@1|root,COG2205@2|Bacteria,1QX6W@1224|Proteobacteria,42ZK5@68525|delta/epsilon subdivisions,2WUSH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158249_k127_2586302_1	1179773.BN6_71490	2.834e-58	212.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DZ76@85010|Pseudonocardiales	201174|Actinobacteria	T	Member of the two-component regulatory system kdpD kdpE involved in the regulation of the kdp operon	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_2586302_3	298654.FraEuI1c_1562	5.305e-20	100.0	COG2093@1|root,COG2093@2|Bacteria	2|Bacteria	K	Spt4/RpoE2 zinc finger	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	DZR,Ion_trans,Ion_trans_2,PP2C_2
SRR25158249_k127_2586302_0	608538.HTH_1418	1.172e-61	221.0	COG0498@1|root,COG0498@2|Bacteria,2G4SE@200783|Aquificae	200783|Aquificae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC_1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158249_k127_2588460_1	686340.Metal_2132	4.044e-104	364.0	COG2373@1|root,COG3209@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,1QV7E@1224|Proteobacteria,1T3HZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	TIGRFAM Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2588460_5	1123239.KB898626_gene760	1.397e-08	59.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158249_k127_2588460_2	324602.Caur_3047	3.31e-32	138.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,376W7@32061|Chloroflexia	32061|Chloroflexia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158249_k127_2588460_6	908340.HMPREF9406_4273	2.033e-05	57.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,36MIS@31979|Clostridiaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158249_k127_2588460_4	1089550.ATTH01000001_gene1811	1.633e-16	87.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1FJDB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	ATP synthase F(0) sector subunit b	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158249_k127_2588460_3	309801.trd_1231	7.971e-25	111.0	COG0712@1|root,COG0712@2|Bacteria,2G78B@200795|Chloroflexi,27YHC@189775|Thermomicrobia	189775|Thermomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158249_k127_2588460_0	765420.OSCT_1158	4.444e-171	544.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi,3759S@32061|Chloroflexia	32061|Chloroflexia	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158249_k127_2594124_0	1254432.SCE1572_47340	4.556e-118	400.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158249_k127_2594124_1	525909.Afer_1639	7.11e-19	98.0	COG3340@1|root,COG3340@2|Bacteria,2HH0B@201174|Actinobacteria,4CP0Q@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158249_k127_2611115_0	1123023.JIAI01000010_gene8623	9.825e-60	215.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria,4E1XU@85010|Pseudonocardiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	proZ	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158249_k127_2611115_1	290398.Csal_1701	3.039e-52	198.0	COG1732@1|root,COG1732@2|Bacteria,1P0VE@1224|Proteobacteria	1224|Proteobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	-	-	-	-	-	-	-	-	-	OpuAC
SRR25158249_k127_2611115_2	309801.trd_0490	2.975e-09	66.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,27Y04@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158249_k127_2611713_4	452637.Oter_3666	7.206e-19	89.0	COG1488@1|root,COG1488@2|Bacteria,46SAG@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158249_k127_2611713_2	1120950.KB892770_gene1397	3.923e-48	189.0	COG0619@1|root,COG0619@2|Bacteria,2IFFR@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158249_k127_2611713_1	1120950.KB892770_gene1396	4.748e-68	256.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria	201174|Actinobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
SRR25158249_k127_2611713_0	1120950.KB892770_gene1395	4.085e-73	255.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria	201174|Actinobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158249_k127_2611713_3	1120950.KB892770_gene1394	1.03e-20	96.0	COG3275@1|root,COG3275@2|Bacteria,2IK2P@201174|Actinobacteria	201174|Actinobacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
SRR25158249_k127_2619712_8	926550.CLDAP_19570	3.617e-07	58.0	2EV6B@1|root,33NM4@2|Bacteria,2G7I5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2619712_5	368407.Memar_2420	5.348e-14	82.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2619712_1	266940.Krad_0365	8.778e-74	269.0	COG3391@1|root,COG3391@2|Bacteria,2I3GE@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2619712_0	446470.Snas_0581	1.577e-87	309.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4EY4J@85014|Glycomycetales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158249_k127_2619712_3	469383.Cwoe_0731	3.262e-52	204.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria	201174|Actinobacteria	CP	ABC-type Na efflux pump, permease	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158249_k127_2619712_2	1449126.JQKL01000016_gene2860	2.928e-73	252.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia	186801|Clostridia	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158249_k127_2619712_7	35754.JNYJ01000020_gene197	6.78e-12	77.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DHBN@85008|Micromonosporales	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158249_k127_2619712_6	685727.REQ_44890	2.963e-13	77.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4FUY8@85025|Nocardiaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158249_k127_2619712_4	1121472.AQWN01000009_gene331	6.468e-27	126.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,262A8@186807|Peptococcaceae	186801|Clostridia	D	SpoIID LytB domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
SRR25158249_k127_2619712_9	479435.Kfla_0797	0.0006089	44.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria	201174|Actinobacteria	S	Involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158249_k127_2622633_2	1122622.ATWJ01000015_gene609	5.379e-50	192.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4FEZM@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158249_k127_2622633_1	219305.MCAG_02550	1.017e-69	258.0	COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria,4DC78@85008|Micromonosporales	201174|Actinobacteria	S	Cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158249_k127_2622633_3	1385517.N800_04515	5.315e-14	85.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,Reprolysin_4,VPEP
SRR25158249_k127_2622633_0	1121403.AUCV01000006_gene428	4.357e-121	407.0	2DBF7@1|root,2Z8X0@2|Bacteria,1QXU4@1224|Proteobacteria,42YFE@68525|delta/epsilon subdivisions,2WTQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
SRR25158249_k127_2635125_1	1172188.KB911820_gene2389	3.602e-55	205.0	COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria,4FH1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158249_k127_2635125_0	512565.AMIS_66800	3.649e-136	456.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DCFG@85008|Micromonosporales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158249_k127_2638035_0	1394178.AWOO02000048_gene6370	8.701e-84	284.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4EIGV@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_2638035_1	479434.Sthe_2500	9.507e-80	278.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia	189775|Thermomicrobia	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158249_k127_2638035_2	1128421.JAGA01000001_gene2350	3.35e-28	122.0	COG1920@1|root,COG1920@2|Bacteria,2NRSN@2323|unclassified Bacteria	2|Bacteria	H	Guanylyl transferase CofC like	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158249_k127_2638035_3	309801.trd_A0706	1.154e-26	112.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,27XY2@189775|Thermomicrobia	189775|Thermomicrobia	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158249_k127_2641104_3	33876.JNXY01000029_gene2662	7.115e-24	102.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4D8QU@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_2641104_1	33876.JNXY01000029_gene2661	5.152e-126	422.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158249_k127_2641104_2	1380390.JIAT01000009_gene408	1.7e-32	139.0	COG0697@1|root,COG0697@2|Bacteria,2GMPU@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158249_k127_2641104_0	485913.Krac_5061	6.616e-141	456.0	COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_2650487_1	479431.Namu_1891	2.615e-57	203.0	COG2197@1|root,COG2197@2|Bacteria,2GNUE@201174|Actinobacteria,4EVX9@85013|Frankiales	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158249_k127_2650487_2	1120949.KB903317_gene1744	9.367e-56	216.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	BsuPI,LysM,PG_binding_1,Peptidase_M15_4
SRR25158249_k127_2650487_3	208439.AJAP_23045	4.047e-46	181.0	COG2885@1|root,COG2885@2|Bacteria,2I4PT@201174|Actinobacteria,4E0BD@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158249_k127_2650487_4	543632.JOJL01000042_gene4456	2.96e-29	134.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	BsuPI,LysM,PG_binding_1,Peptidase_M15_4
SRR25158249_k127_2650487_0	1343740.M271_05185	1.119e-172	556.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria	201174|Actinobacteria	O	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158249_k127_2656689_0	292459.STH1417	2.064e-83	284.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia	186801|Clostridia	E	PFAM DAHP synthetase I	aroF1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158249_k127_2656689_1	367299.JOEE01000004_gene1085	1.902e-17	87.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin,Lipoprotein_15
SRR25158249_k127_2660725_0	981384.AEYW01000018_gene3284	7.2e-71	254.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,4NCZM@97050|Ruegeria	28211|Alphaproteobacteria	L	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
SRR25158249_k127_2660725_1	1242864.D187_010427	2.874e-55	212.0	2E458@1|root,32Z1A@2|Bacteria,1PAGT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2660848_4	1219049.SP5_004_00120	4.031e-18	88.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2TUJQ@28211|Alphaproteobacteria,2K0FC@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2660848_5	324602.Caur_0509	3.729e-17	93.0	COG1430@1|root,COG1430@2|Bacteria,2GAEN@200795|Chloroflexi,375TZ@32061|Chloroflexia	32061|Chloroflexia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158249_k127_2660848_2	479434.Sthe_0521	3.305e-70	252.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,27XSY@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158249_k127_2660848_3	479434.Sthe_0520	1.104e-63	233.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,27XX2@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158249_k127_2660848_0	479434.Sthe_0519	1.727e-203	642.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158249_k127_2660848_1	316274.Haur_4612	8.388e-101	344.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158249_k127_2660848_6	309801.trd_1013	1.503e-10	72.0	COG3745@1|root,COG3745@2|Bacteria,2G7H3@200795|Chloroflexi,27XF4@189775|Thermomicrobia	189775|Thermomicrobia	U	SAF	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158249_k127_2660848_7	1121423.JONT01000021_gene58	5.78e-07	54.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,24UMJ@186801|Clostridia	186801|Clostridia	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158249_k127_2660848_9	370438.PTH_1445	5.509e-06	50.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,259NT@186801|Clostridia,263C9@186807|Peptococcaceae	186801|Clostridia	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158249_k127_2660848_8	370438.PTH_1445	3.911e-06	50.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,259NT@186801|Clostridia,263C9@186807|Peptococcaceae	186801|Clostridia	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158249_k127_26609_2	562970.Btus_0711	1.825e-107	355.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,27881@186823|Alicyclobacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158249_k127_26609_7	1128421.JAGA01000002_gene1099	1.879e-36	146.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158249_k127_26609_5	401526.TcarDRAFT_1875	2.57e-58	226.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158249_k127_26609_3	933115.GPDM_10360	1.122e-75	267.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,26EWK@186818|Planococcaceae	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158249_k127_26609_4	443144.GM21_1592	5.18e-68	242.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158249_k127_26609_0	867903.ThesuDRAFT_01077	1.187e-115	394.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WCYH@538999|Clostridiales incertae sedis	186801|Clostridia	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158249_k127_26609_1	511051.CSE_11670	2.258e-112	390.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppF	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678	3.6.3.24	ko:K02031,ko:K02032,ko:K10823,ko:K10824,ko:K12372,ko:K13892	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00324,M00348,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAPECO1_1312.APECO1_362,iEC042_1314.EC042_1615,iEC042_1314.EC042_3846,iECABU_c1320.ECABU_c39820,iECED1_1282.ECED1_4219,iECH74115_1262.ECH74115_2095,iECOK1_1307.ECOK1_1402,iECS88_1305.ECS88_1315,iECSP_1301.ECSP_1968,iECUMN_1333.ECUMN_1737,iECW_1372.ECW_m1611,iECs_1301.ECs2087,iEKO11_1354.EKO11_2337,iPC815.YPO3999,iSF_1195.SF3575,iSFxv_1172.SFxv_3897,iS_1188.S4195,iUMN146_1321.UM146_10835,iUTI89_1310.UTI89_C1445,iWFL_1372.ECW_m1611,iZ_1308.Z2227,ic_1306.c4355	ABC_tran,oligo_HPY
SRR25158249_k127_26609_6	765420.OSCT_0207	1.919e-47	182.0	COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158249_k127_2669485_0	525904.Tter_0763	4.345e-51	205.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158249_k127_2669485_1	644966.Tmar_0200	6.601e-10	72.0	29Y0M@1|root,30JTI@2|Bacteria,1VEVD@1239|Firmicutes,24QVV@186801|Clostridia,3WDJ2@538999|Clostridiales incertae sedis	186801|Clostridia	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158249_k127_2678899_1	1379270.AUXF01000007_gene919	5.215e-24	106.0	COG5587@1|root,COG5587@2|Bacteria,1ZTH8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158249_k127_2678899_2	153721.MYP_3548	2.807e-14	85.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,47QYP@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
SRR25158249_k127_2678899_0	1297742.A176_02530	1.121e-28	119.0	COG3759@1|root,COG3759@2|Bacteria,1Q699@1224|Proteobacteria,432NU@68525|delta/epsilon subdivisions,2WXI7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
SRR25158249_k127_2683690_1	479434.Sthe_2602	1.048e-28	124.0	COG1670@1|root,COG1670@2|Bacteria,2G8SC@200795|Chloroflexi,27YIG@189775|Thermomicrobia	189775|Thermomicrobia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_2683690_0	1158050.KB895452_gene556	2.305e-83	284.0	COG1028@1|root,COG1028@2|Bacteria,2GWHQ@201174|Actinobacteria,1WBND@1268|Micrococcaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158249_k127_2683690_3	1040989.AWZU01000021_gene2149	3.287e-10	68.0	COG3794@1|root,COG3794@2|Bacteria,1RGHH@1224|Proteobacteria,2UMFA@28211|Alphaproteobacteria,3K47H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158249_k127_2683690_2	160799.PBOR_12065	1.884e-21	98.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158249_k127_2706590_1	443255.SCLAV_4708	2.691e-64	229.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158249_k127_2706590_0	861299.J421_0915	6.006e-104	356.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158249_k127_2706590_2	65497.JODV01000003_gene4715	1.673e-14	81.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E3X3@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158249_k127_2731891_1	326427.Cagg_1607	1.27e-52	192.0	COG1666@1|root,COG1666@2|Bacteria,2G6TD@200795|Chloroflexi,375J1@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158249_k127_2731891_0	298655.KI912266_gene5156	1.709e-56	213.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4ERUC@85013|Frankiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158249_k127_2741695_3	1521187.JPIM01000060_gene2905	1.89e-66	243.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158249_k127_2741695_1	543632.JOJL01000010_gene7177	1.353e-70	265.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158249_k127_2741695_2	314230.DSM3645_15870	5.531e-70	246.0	COG0566@1|root,COG0566@2|Bacteria,2IZJR@203682|Planctomycetes	203682|Planctomycetes	H	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158249_k127_2741695_4	314230.DSM3645_15875	8.837e-57	209.0	COG1092@1|root,COG1092@2|Bacteria,2J2ZW@203682|Planctomycetes	203682|Planctomycetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR25158249_k127_2741695_0	644966.Tmar_0825	1.96e-182	591.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WCD0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158249_k127_2741695_5	1035308.AQYY01000001_gene1338	1.314e-54	213.0	COG0457@1|root,COG0457@2|Bacteria	1035308.AQYY01000001_gene1338|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2750384_1	485913.Krac_12501	1.37e-53	194.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158249_k127_2750384_5	871963.Desdi_0464	9.575e-32	127.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,2621E@186807|Peptococcaceae	186801|Clostridia	J	PFAM ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158249_k127_2750384_4	1121090.KB894720_gene1914	5.132e-44	170.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158249_k127_2750384_2	443254.Marpi_1669	3.878e-48	187.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158249_k127_2750384_3	867903.ThesuDRAFT_00593	6.685e-48	179.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WD8E@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158249_k127_2750384_0	1128421.JAGA01000003_gene3154	4.699e-96	324.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158249_k127_2751727_3	861450.HMPREF0080_00230	7.333e-67	232.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H38B@909932|Negativicutes	909932|Negativicutes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158249_k127_2751727_5	479435.Kfla_1126	7.606e-31	131.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2751727_2	1380394.JADL01000026_gene4730	1.279e-71	253.0	COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,2TUCY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158249_k127_2751727_1	1158338.JNLJ01000001_gene371	3.852e-121	402.0	COG0136@1|root,COG0136@2|Bacteria,2G3QW@200783|Aquificae	200783|Aquificae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158249_k127_2751727_4	525904.Tter_0795	7.471e-56	214.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158249_k127_2751727_0	1382304.JNIL01000001_gene550	1.605e-193	618.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,277WB@186823|Alicyclobacillaceae	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158249_k127_2751727_6	324602.Caur_1228	6.71e-07	59.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,3753X@32061|Chloroflexia	32061|Chloroflexia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158249_k127_2759522_0	356851.JOAN01000018_gene5617	1.042e-62	226.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4DDRS@85008|Micromonosporales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158249_k127_2759522_1	446470.Snas_4064	8.276e-59	220.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4F0C7@85014|Glycomycetales	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_2769835_0	266117.Rxyl_1779	1.482e-59	220.0	COG4529@1|root,COG4529@2|Bacteria,2GNX3@201174|Actinobacteria,4CR8M@84995|Rubrobacteria	84995|Rubrobacteria	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRR25158249_k127_2769835_1	1032480.MLP_12400	4.06e-26	109.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4DQCE@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158249_k127_277128_1	936589.HMPREF1521_0240	1.106e-68	241.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4H35I@909932|Negativicutes	909932|Negativicutes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158249_k127_277128_0	1147.D082_04050	4.981e-93	319.0	COG0528@1|root,COG0528@2|Bacteria,1G0CR@1117|Cyanobacteria,1H56X@1142|Synechocystis	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158249_k127_277128_2	158189.SpiBuddy_1216	2.629e-28	128.0	COG0233@1|root,COG0233@2|Bacteria,2J6PZ@203691|Spirochaetes	203691|Spirochaetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158249_k127_277577_3	1121272.KB903249_gene1629	3.944e-59	212.0	COG1309@1|root,COG1309@2|Bacteria,2IHGM@201174|Actinobacteria,4DD7T@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158249_k127_277577_4	1121272.KB903283_gene4946	1.196e-26	113.0	2CIH2@1|root,32QT5@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158249_k127_277577_0	1380390.JIAT01000013_gene123	2.155e-88	304.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158249_k127_277577_2	1380390.JIAT01000013_gene123	5.14e-68	248.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158249_k127_277577_1	935839.JAGJ01000005_gene2701	8.206e-70	245.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158249_k127_2776390_0	290397.Adeh_3062	1.11e-54	208.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158249_k127_2776390_1	502025.Hoch_2176	6.404e-31	135.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2778943_0	1123321.KB905818_gene4883	5.661e-105	357.0	COG1028@1|root,COG1211@1|root,COG1028@2|Bacteria,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	1.1.1.405,2.7.7.40,2.7.7.60	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R01525,R02921,R05633	RC00002,RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
SRR25158249_k127_2778943_1	445971.ANASTE_01152	2.364e-74	265.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glyphos_transf
SRR25158249_k127_2779017_0	316274.Haur_4823	1.659e-74	260.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158249_k127_2779017_1	861299.J421_3610	4.436e-31	131.0	COG0662@1|root,COG0662@2|Bacteria,1ZTKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158249_k127_2779017_2	243164.DET0018	1.449e-23	102.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi,34DFF@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2786772_2	479434.Sthe_0954	5.059e-18	90.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158249_k127_2786772_0	696281.Desru_2974	6.344e-40	155.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,262K4@186807|Peptococcaceae	186801|Clostridia	S	PFAM peptidase	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158249_k127_2786772_3	1382306.JNIM01000001_gene3902	1.639e-11	72.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2786772_1	324602.Caur_3228	1.032e-21	109.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi,375MQ@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158249_k127_2786772_4	383372.Rcas_4453	1.576e-06	59.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,375NU@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158249_k127_2793234_2	240015.ACP_2221	1.766e-19	98.0	COG0533@1|root,COG0533@2|Bacteria,3Y2PN@57723|Acidobacteria,2JHJ0@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158249_k127_2793234_0	401526.TcarDRAFT_0379	7.279e-40	160.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4H4WN@909932|Negativicutes	909932|Negativicutes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158249_k127_2793234_3	1120985.AUMI01000017_gene2700	3.392e-15	87.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158249_k127_2793234_1	360911.EAT1b_2084	4.556e-31	127.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3WETQ@539002|Bacillales incertae sedis	91061|Bacilli	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158249_k127_2794835_4	1318628.MARLIPOL_16944	2.74e-07	55.0	COG1196@1|root,COG1196@2|Bacteria,1QU97@1224|Proteobacteria,1T3AS@1236|Gammaproteobacteria,467TR@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG0419 ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
SRR25158249_k127_2794835_1	269799.Gmet_1223	9.057e-32	141.0	COG0420@1|root,COG0420@2|Bacteria,1MXMJ@1224|Proteobacteria,42Q5U@68525|delta/epsilon subdivisions,2WINF@28221|Deltaproteobacteria,43SKW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Calcineurin-like phosphoesterase	sbcD-1	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158249_k127_2794835_2	1121422.AUMW01000025_gene349	1.824e-30	124.0	COG1278@1|root,COG1278@2|Bacteria,1VWWT@1239|Firmicutes,251UG@186801|Clostridia,265GV@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158249_k127_2794835_3	1121946.AUAX01000019_gene7777	2.02e-29	130.0	COG3340@1|root,COG3340@2|Bacteria,2ISWE@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158249_k127_2794835_0	929712.KI912613_gene3955	2.476e-63	237.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4CQ34@84995|Rubrobacteria	84995|Rubrobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158249_k127_2798733_1	1122939.ATUD01000004_gene3844	4.485e-47	175.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158249_k127_2798733_0	479432.Sros_1323	9.103e-131	435.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4EHTY@85012|Streptosporangiales	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158249_k127_2816854_5	1123367.C666_12815	5.273e-30	127.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales	206389|Rhodocyclales	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158249_k127_2816854_4	1158050.KB895456_gene1947	5.361e-67	251.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,1W86W@1268|Micrococcaceae	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158249_k127_2816854_0	1121024.AUCD01000028_gene1324	9.049e-166	536.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,27FKR@186828|Carnobacteriaceae	91061|Bacilli	S	ATPases associated with a variety of cellular activities	mglA	-	3.6.3.17	ko:K02056,ko:K06400	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158249_k127_2816854_2	926569.ANT_27900	2.289e-76	282.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158249_k127_2816854_1	1380354.JIAN01000008_gene3501	3.34e-86	301.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4F0KC@85016|Cellulomonadaceae	201174|Actinobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158249_k127_2816854_3	253839.SSNG_06419	5.037e-67	256.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria	201174|Actinobacteria	F	nucleoside hydrolase	ybeK	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158249_k127_2816854_6	199310.c0735	3.797e-21	95.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,1RSCY@1236|Gammaproteobacteria,3XN0M@561|Escherichia	1236|Gammaproteobacteria	F	Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively	rihA	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598	IU_nuc_hydro
SRR25158249_k127_2816957_0	264732.Moth_1139	2.667e-56	206.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,42FMF@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158249_k127_2816957_1	926569.ANT_14000	3.989e-24	110.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
SRR25158249_k127_2823890_2	1968.JOEV01000003_gene3296	1.009e-25	109.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria	201174|Actinobacteria	S	protein containing SIS (Sugar isomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158249_k127_2823890_1	1082933.MEA186_20789	1.204e-115	385.0	COG1879@1|root,COG1879@2|Bacteria,1MUEI@1224|Proteobacteria,2TZUI@28211|Alphaproteobacteria,43IRR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158249_k127_2823890_0	1297569.MESS2_1340010	1.683e-203	647.0	COG1129@1|root,COG1129@2|Bacteria,1R8D8@1224|Proteobacteria,2U4HH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158249_k127_2834628_0	1242864.D187_003500	5.998e-31	137.0	COG0642@1|root,COG2205@2|Bacteria	1242864.D187_003500|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2834628_1	1476583.DEIPH_ctg103orf0058	4.052e-19	102.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR25158249_k127_2834628_2	1107311.Q767_07625	0.000154	49.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1HWZN@117743|Flavobacteriia,2NTR9@237|Flavobacterium	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158249_k127_2840872_2	710696.Intca_2118	1.906e-30	128.0	COG2267@1|root,COG2267@2|Bacteria,2IAIJ@201174|Actinobacteria,4FEVQ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158249_k127_2840872_0	309799.DICTH_1516	4.728e-110	364.0	COG1210@1|root,COG1210@2|Bacteria	2|Bacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
SRR25158249_k127_2840872_1	1382356.JQMP01000003_gene1359	2.117e-87	313.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158249_k127_2841585_0	218284.CCDN010000001_gene555	5.939e-87	301.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus	91061|Bacilli	L	COG1796 DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158249_k127_2841585_1	357808.RoseRS_1879	2.552e-38	155.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi,375HW@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2
SRR25158249_k127_2843840_1	1340493.JNIF01000004_gene1019	2.895e-15	76.0	COG0821@1|root,COG0821@2|Bacteria,3Y2GU@57723|Acidobacteria	57723|Acidobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158249_k127_2843840_0	264732.Moth_1047	2.002e-106	361.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,42EQU@68295|Thermoanaerobacterales	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158249_k127_2867187_1	765420.OSCT_1966	1.163e-44	166.0	COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158249_k127_2867187_0	357808.RoseRS_1889	1.784e-67	243.0	COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158249_k127_2867187_2	357808.RoseRS_1890	6.628e-36	154.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158249_k127_2884310_0	401526.TcarDRAFT_2083	1.762e-123	401.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158249_k127_2884310_2	981384.AEYW01000014_gene116	1.151e-67	243.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,4NB9U@97050|Ruegeria	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158249_k127_2884310_1	981384.AEYW01000014_gene117	9.102e-83	290.0	COG1176@1|root,COG1176@2|Bacteria,1P34V@1224|Proteobacteria,2U1N8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component I	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158249_k127_2884310_3	670487.Ocepr_0988	6.276e-57	214.0	COG0687@1|root,COG0687@2|Bacteria,1WIQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
SRR25158249_k127_2884310_4	1121272.KB903292_gene3846	6.8e-06	53.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DCE9@85008|Micromonosporales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158249_k127_288552_4	649831.L083_3555	2.758e-54	198.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4DIRB@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_288552_1	1120949.KB903305_gene7196	1.143e-191	610.0	COG1653@1|root,COG1653@2|Bacteria,2GNYN@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
SRR25158249_k127_288552_2	1120949.KB903305_gene7197	9.588e-119	389.0	COG1175@1|root,COG1175@2|Bacteria,2GMJG@201174|Actinobacteria,4D8HW@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
SRR25158249_k127_288552_3	1120949.KB903305_gene7198	1.954e-113	388.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4D953@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158249_k127_288552_0	1120949.KB903305_gene7199	2.298e-206	657.0	COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria	201174|Actinobacteria	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
SRR25158249_k127_2888361_0	379066.GAU_1792	7.211e-73	269.0	COG0329@1|root,COG0329@2|Bacteria,1ZSM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158249_k127_2888361_1	861299.J421_3425	1.215e-20	101.0	COG0289@1|root,COG0289@2|Bacteria,1ZTHH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158249_k127_2895972_3	1501230.ET33_25475	2.667e-46	182.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,26RV6@186822|Paenibacillaceae	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158249_k127_2895972_1	1382356.JQMP01000004_gene472	2.229e-89	328.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,27XZI@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158249_k127_2895972_2	525904.Tter_1614	3.423e-76	278.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
SRR25158249_k127_2895972_0	479434.Sthe_1998	4.113e-102	342.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158249_k127_291010_0	525904.Tter_0063	3.332e-212	680.0	COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158249_k127_291010_1	525904.Tter_0064	5.635e-78	271.0	COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
SRR25158249_k127_291010_2	485913.Krac_8502	5.773e-52	187.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158249_k127_2912403_1	314271.RB2654_04471	3.455e-08	59.0	COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
SRR25158249_k127_2912403_0	525904.Tter_0881	2.198e-224	704.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158249_k127_2912506_0	1123269.NX02_01130	4.716e-139	453.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,2VFCV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C
SRR25158249_k127_2912506_1	29306.JOBE01000051_gene6709	4.071e-101	353.0	COG1752@1|root,COG1752@2|Bacteria,2IPBH@201174|Actinobacteria	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158249_k127_2912506_2	1144312.PMI09_06032	1.007e-26	115.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158249_k127_2925367_1	1229780.BN381_220038	1.178e-09	65.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
SRR25158249_k127_2932120_1	526225.Gobs_1484	1.343e-30	137.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria,4ERMU@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158249_k127_2932120_0	1211815.CBYP010000018_gene2836	1.795e-94	327.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4ESB1@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_2932120_2	349519.LCK_01683	3.782e-18	87.0	COG0580@1|root,COG0580@2|Bacteria,1UZX3@1239|Firmicutes,4HA8I@91061|Bacilli,4AWSA@81850|Leuconostocaceae	91061|Bacilli	U	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158249_k127_2934282_0	867903.ThesuDRAFT_00195	3.908e-221	702.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,25EG8@186801|Clostridia,3WDQS@538999|Clostridiales incertae sedis	186801|Clostridia	KL	PFAM Helicase conserved C-terminal domain	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158249_k127_2942277_1	452652.KSE_14040	6.342e-15	85.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,2M430@2063|Kitasatospora	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158249_k127_2942277_0	1009370.ALO_19932	8.091e-26	119.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4H2TB@909932|Negativicutes	909932|Negativicutes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158249_k127_2950150_4	1131730.BAVI_19419	1.632e-39	149.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,1ZDCS@1386|Bacillus	91061|Bacilli	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158249_k127_2950150_2	1487953.JMKF01000045_gene2754	1.304e-51	190.0	COG0745@1|root,COG0745@2|Bacteria,1FZWD@1117|Cyanobacteria,1HA1B@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_2950150_3	1200792.AKYF01000006_gene1406	2.608e-50	198.0	COG5002@1|root,COG5002@2|Bacteria,1TS5K@1239|Firmicutes,4H9Y1@91061|Bacilli,277BU@186822|Paenibacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	ciaH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K14982	ko02020,ko02024,map02020,map02024	M00521	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158249_k127_2950150_1	37919.EP51_03085	5.024e-69	249.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4G1XB@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2950150_0	479434.Sthe_0935	2.798e-100	341.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,27XJV@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158249_k127_2950150_5	446465.Bfae_14770	1.177e-12	72.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4FBU4@85020|Dermabacteraceae	201174|Actinobacteria	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158249_k127_295041_2	1232410.KI421420_gene3186	2.799e-57	210.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2X5VM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_295041_1	1232410.KI421420_gene3185	1.213e-59	223.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,439YG@68525|delta/epsilon subdivisions,2WUBB@28221|Deltaproteobacteria,43UAD@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158249_k127_295041_3	909613.UO65_1809	1.402e-16	88.0	COG1672@1|root,COG1672@2|Bacteria,2IGAA@201174|Actinobacteria,4E466@85010|Pseudonocardiales	201174|Actinobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158249_k127_295041_0	935948.KE386494_gene334	4.55e-165	537.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,42FMZ@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158249_k127_2956989_3	562970.Btus_2659	5.738e-32	134.0	COG4097@1|root,COG4097@2|Bacteria,1VAMR@1239|Firmicutes,4HKN3@91061|Bacilli,278P1@186823|Alicyclobacillaceae	91061|Bacilli	P	Ferric reductase like transmembrane component	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158249_k127_2956989_2	266117.Rxyl_1141	5.009e-58	213.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158249_k127_2956989_5	309801.trd_A0182	1.2e-23	115.0	COG0735@1|root,COG0735@2|Bacteria,2G74Y@200795|Chloroflexi,27YIH@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158249_k127_2956989_0	479434.Sthe_2975	1.456e-76	273.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,27XKB@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC 3 transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158249_k127_2956989_1	479434.Sthe_2976	1.696e-76	267.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,27XH6@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158249_k127_2956989_4	1382356.JQMP01000003_gene1647	4.361e-25	113.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158249_k127_2957919_0	1345697.M493_13375	3.154e-93	329.0	COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1WE5V@129337|Geobacillus	91061|Bacilli	L	Single-strand DNA-specific exonuclease, C terminal domain	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
SRR25158249_k127_2957919_1	309801.trd_0649	1.07e-21	97.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158249_k127_2960368_2	1382306.JNIM01000001_gene2450	2.62e-10	65.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158249_k127_2960368_0	1382306.JNIM01000001_gene2451	4.105e-67	242.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi	200795|Chloroflexi	O	YHS domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158249_k127_2960368_1	518766.Rmar_2766	6.122e-67	229.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158249_k127_2977128_0	309801.trd_0274	1.455e-48	194.0	COG5438@1|root,COG5438@2|Bacteria	2|Bacteria	S	YibE/F-like protein	yibE	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158249_k127_2980366_1	1214101.BN159_2363	2.265e-11	74.0	COG0451@1|root,COG0451@2|Bacteria,2GKZX@201174|Actinobacteria	201174|Actinobacteria	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158249_k127_2980366_0	768671.ThimaDRAFT_3482	1.165e-78	286.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_2981535_1	1229780.BN381_220038	3.158e-12	72.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
SRR25158249_k127_2981535_0	1242864.D187_000827	1.934e-258	866.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2X5HN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158249_k127_2990380_2	644968.DFW101_1162	2.537e-22	102.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2M7YQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158249_k127_2990380_0	1120960.ATXG01000013_gene3522	5.103e-68	248.0	COG0604@1|root,COG0604@2|Bacteria,2I8SZ@201174|Actinobacteria,4FPGS@85023|Microbacteriaceae	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_2990380_1	471853.Bcav_0494	5.314e-39	148.0	COG1695@1|root,COG1695@2|Bacteria,2IQ51@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158249_k127_2991827_0	1121017.AUFG01000002_gene2742	7.442e-67	239.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria,4FF7A@85021|Intrasporangiaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158249_k127_2991827_2	869210.Marky_1369	1.662e-47	178.0	COG2151@1|root,COG2151@2|Bacteria,1WJW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158249_k127_2991827_1	869210.Marky_1368	7.023e-57	209.0	COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158249_k127_2991827_4	869210.Marky_1367	8.05e-18	91.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR25158249_k127_2991827_3	869210.Marky_1366	2.829e-22	97.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158249_k127_2998260_2	457429.ABJI02000385_gene4491	2.946e-16	92.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158249_k127_2998260_0	935557.ATYB01000010_gene228	5.042e-95	338.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,2TX1P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158249_k127_2998260_1	1380356.JNIK01000017_gene2986	4.075e-19	95.0	COG1309@1|root,COG1309@2|Bacteria,2GNQ6@201174|Actinobacteria,4EVPV@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158249_k127_2999946_0	573370.DMR_28000	4.749e-42	170.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,2M90Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158249_k127_2999946_1	1313172.YM304_04030	9.716e-19	94.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158249_k127_2999946_2	1356854.N007_11050	9.429e-05	51.0	2EUC9@1|root,33MUN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3006933_2	479434.Sthe_2502	1.01e-10	66.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158249_k127_3006933_0	309801.trd_1481	2.465e-56	214.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,27Y5S@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158249_k127_3006933_1	1123388.AQWU01000068_gene992	5.604e-30	130.0	COG0357@1|root,COG0357@2|Bacteria,1WIYE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158249_k127_3019687_1	563192.HMPREF0179_00664	4.132e-79	276.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42N64@68525|delta/epsilon subdivisions,2WJ73@28221|Deltaproteobacteria,2M7RI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158249_k127_3019687_0	1382306.JNIM01000001_gene1701	1.223e-80	295.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158249_k127_3019687_2	1157640.AQWO01000009_gene746	4.452e-20	96.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158249_k127_3035506_1	1035308.AQYY01000002_gene31	1.676e-21	97.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158249_k127_3035506_0	1382356.JQMP01000004_gene63	1.412e-104	365.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158249_k127_3036757_0	479434.Sthe_1003	5.993e-183	585.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158249_k127_3036757_1	1329516.JPST01000014_gene547	8.448e-13	68.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,27AYA@186824|Thermoactinomycetaceae	91061|Bacilli	G	Transaldolase/Fructose-6-phosphate aldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158249_k127_3038956_0	1128421.JAGA01000002_gene158	9.995e-126	416.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	MA20_20675	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158249_k127_3038956_1	765420.OSCT_0207	4.928e-20	105.0	COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158249_k127_3039235_1	1463861.JNXE01000033_gene2763	4.62e-08	64.0	COG0463@1|root,COG1216@1|root,COG1887@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,COG1887@2|Bacteria,2GM0T@201174|Actinobacteria	201174|Actinobacteria	M	CDP-glycerol poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
SRR25158249_k127_3039235_0	42256.RradSPS_1174	2.798e-98	335.0	COG1216@1|root,COG4122@1|root,COG4641@1|root,COG1216@2|Bacteria,COG4122@2|Bacteria,COG4641@2|Bacteria,2IT06@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158249_k127_3043624_0	1089545.KB913037_gene523	1.11e-40	175.0	COG4585@1|root,COG5002@1|root,COG4585@2|Bacteria,COG5002@2|Bacteria,2IAG1@201174|Actinobacteria,4DXP6@85010|Pseudonocardiales	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR25158249_k127_3043624_1	1120950.KB892767_gene5157	1.237e-11	79.0	COG2203@1|root,COG2508@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria,4DPRW@85009|Propionibacteriales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_30
SRR25158249_k127_3053470_0	436229.JOEH01000006_gene2694	4.512e-128	414.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,2NFPS@228398|Streptacidiphilus	201174|Actinobacteria	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158249_k127_3053470_1	471853.Bcav_2611	1.932e-92	319.0	COG2978@1|root,COG2978@2|Bacteria,2GN45@201174|Actinobacteria	201174|Actinobacteria	H	transporter	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
SRR25158249_k127_3074287_0	105422.BBPM01000097_gene5229	8.437e-97	334.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,2NH21@228398|Streptacidiphilus	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158249_k127_3074287_1	1236902.ANAS01000004_gene3774	2.135e-06	52.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4EGMJ@85012|Streptosporangiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158249_k127_3074310_3	309801.trd_0965	4.546e-42	160.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158249_k127_3074310_5	1235794.C811_00991	7.938e-34	142.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CVMS@84998|Coriobacteriia	84998|Coriobacteriia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158249_k127_3074310_8	397290.C810_00314	1.714e-11	68.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,27PMP@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158249_k127_3074310_1	373903.Hore_01340	3.977e-59	215.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WAKQ@53433|Halanaerobiales	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158249_k127_3074310_4	1463821.JOGR01000003_gene788	1.257e-38	148.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4EYS7@85014|Glycomycetales	201174|Actinobacteria	J	Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158249_k127_3074310_0	593907.Celgi_0831	2.541e-70	242.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4F206@85016|Cellulomonadaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158249_k127_3074310_2	1408254.T458_24820	1.312e-42	162.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,26WQU@186822|Paenibacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158249_k127_3074310_6	335543.Sfum_1568	6.205e-22	98.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2MS3E@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158249_k127_3074310_7	525904.Tter_0727	1.149e-14	73.0	COG0094@1|root,COG0094@2|Bacteria,2NP65@2323|unclassified Bacteria	2|Bacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158249_k127_3075093_0	1121946.AUAX01000015_gene6097	2.724e-36	154.0	COG1470@1|root,COG1470@2|Bacteria,2H4ZH@201174|Actinobacteria,4DDR7@85008|Micromonosporales	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158249_k127_3075093_3	1380346.JNIH01000011_gene2740	3.568e-09	70.0	2BZJQ@1|root,334P7@2|Bacteria,2I8YZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158249_k127_3075093_1	1242864.D187_006577	5.136e-18	98.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158249_k127_3075093_2	1172186.KB911470_gene3168	7.296e-17	86.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2I348@201174|Actinobacteria,2384I@1762|Mycobacteriaceae	201174|Actinobacteria	KT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158249_k127_3075197_1	561175.KB894096_gene733	2.742e-33	137.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4EGJA@85012|Streptosporangiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158249_k127_3075197_2	698769.JFBD01000005_gene2929	1.466e-13	80.0	COG4758@1|root,COG4758@2|Bacteria,1VE20@1239|Firmicutes	1239|Firmicutes	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
SRR25158249_k127_3075197_0	1298863.AUEP01000008_gene1247	4.182e-126	413.0	COG0404@1|root,COG0404@2|Bacteria,2I8C4@201174|Actinobacteria,4DTFF@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1989,GCV_T,GCV_T_C
SRR25158249_k127_3087098_0	926560.KE387023_gene2049	4.233e-30	123.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRR25158249_k127_3091814_0	525263.HMPREF0298_0307	4.865e-106	356.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,22JYB@1653|Corynebacteriaceae	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158249_k127_3091814_1	525904.Tter_1099	2.769e-49	190.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_310370_1	211114.JOEF01000023_gene5698	7.617e-26	123.0	COG1309@1|root,COG1309@2|Bacteria,2IFH9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158249_k127_310370_0	37919.EP51_00195	1.233e-78	284.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria,4FYKD@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	sppF	-	1.14.13.200	ko:K14672,ko:K15972	ko01057,ko01130,map01057,map01130	M00783	R06704,R10954	RC02681	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	FAD_binding_3
SRR25158249_k127_3128873_0	552811.Dehly_1121	5.588e-79	274.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,34CPV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158249_k127_3128873_1	272123.Anacy_5591	3.078e-64	243.0	COG1364@1|root,COG1364@2|Bacteria,1G1H7@1117|Cyanobacteria,1HIDX@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argJ	ArgJ
SRR25158249_k127_3128873_2	106370.Francci3_3173	7.777e-26	116.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4ERTB@85013|Frankiales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158249_k127_3146251_3	383372.Rcas_2758	0.0008289	53.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methionine synthase, vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158249_k127_3146251_1	1128421.JAGA01000002_gene1027	4.128e-27	125.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158249_k127_3146251_0	118166.JH976537_gene4842	4.288e-54	201.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HAGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158249_k127_3146251_2	67257.JODR01000006_gene2639	3.408e-05	53.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158249_k127_315126_1	530564.Psta_0808	1.636e-25	111.0	COG0517@1|root,COG0517@2|Bacteria,2J0MQ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158249_k127_315126_0	1306990.BARG01000102_gene9631	1.313e-101	348.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158249_k127_3178332_1	867903.ThesuDRAFT_02351	2.473e-69	248.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WCNC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158249_k127_3178332_2	1382306.JNIM01000001_gene3651	1.102e-58	214.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158249_k127_3178332_0	1173028.ANKO01000190_gene422	1.861e-106	363.0	COG0128@1|root,COG0128@2|Bacteria,1G1F9@1117|Cyanobacteria,1H72W@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158249_k127_3178332_3	1382304.JNIL01000001_gene427	8.652e-11	64.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,2781M@186823|Alicyclobacillaceae	91061|Bacilli	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158249_k127_3178629_3	68570.DC74_7348	1.957e-19	97.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08166	-	-	-	-	ko00000,ko02000	2.A.1.3.10	-	-	MFS_1
SRR25158249_k127_3178629_0	1120792.JAFV01000001_gene1090	2.646e-132	442.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,36XF8@31993|Methylocystaceae	28211|Alphaproteobacteria	J	tRNA synthetases class I (C) catalytic domain	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158249_k127_3178629_1	290397.Adeh_1315	1.829e-44	172.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2YUWH@29|Myxococcales	28221|Deltaproteobacteria	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158249_k127_3178629_2	1429046.RR21198_0712	2.322e-39	160.0	COG1808@1|root,COG1808@2|Bacteria,2HHA9@201174|Actinobacteria,4FWG3@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158249_k127_3192655_0	525904.Tter_0079	2.341e-80	285.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	6.3.2.2	ko:K01919,ko:K03072,ko:K12257	ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070	M00118,M00335	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	GshA,SecD_SecF,Sec_GG
SRR25158249_k127_3192655_1	1382356.JQMP01000003_gene2165	4.031e-58	217.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158249_k127_3192935_3	525904.Tter_0130	2.324e-31	134.0	COG1470@1|root,COG1470@2|Bacteria,2NR3G@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158249_k127_3192935_1	592026.GCWU0000282_000060	1.241e-62	226.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_3192935_2	646529.Desaci_4419	7.731e-41	162.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,262W8@186807|Peptococcaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR25158249_k127_3192935_5	1123354.AUDR01000014_gene927	7.685e-08	65.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,1KRNP@119069|Hydrogenophilales	119069|Hydrogenophilales	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
SRR25158249_k127_3192935_6	756272.Plabr_1203	0.000138	55.0	COG0760@1|root,COG0760@2|Bacteria,2J034@203682|Planctomycetes	203682|Planctomycetes	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
SRR25158249_k127_3192935_0	292459.STH3231	1.324e-71	259.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia	186801|Clostridia	K	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRR25158249_k127_3192935_4	411467.BACCAP_04643	4.604e-14	77.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,267NV@186813|unclassified Clostridiales	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
SRR25158249_k127_3196498_0	1125863.JAFN01000001_gene559	3.281e-204	651.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158249_k127_3201782_2	411467.BACCAP_03473	2.596e-17	81.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158249_k127_3201782_0	1382306.JNIM01000001_gene3761	1.16e-50	200.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158249_k127_3201782_1	497964.CfE428DRAFT_4166	8.018e-31	129.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158249_k127_3203412_7	324602.Caur_2208	3.871e-27	114.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,3755C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158249_k127_3203412_4	326427.Cagg_2916	3.347e-86	295.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158249_k127_3203412_5	405948.SACE_1590	1.221e-61	233.0	COG2971@1|root,COG2971@2|Bacteria,2GKNB@201174|Actinobacteria,4E0TB@85010|Pseudonocardiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158249_k127_3203412_8	649639.Bcell_0810	4.124e-25	114.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,4HAQI@91061|Bacilli,1ZBYP@1386|Bacillus	91061|Bacilli	G	deacetylase	pdaA	GO:0005575,GO:0016020	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158249_k127_3203412_1	926550.CLDAP_13290	9.069e-128	418.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158249_k127_3203412_2	926550.CLDAP_13300	3.031e-119	391.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
SRR25158249_k127_3203412_3	926550.CLDAP_13310	2.536e-118	407.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158249_k127_3203412_6	1227261.HMPREF0043_00480	7.619e-59	214.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4D51Y@85005|Actinomycetales	201174|Actinobacteria	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158249_k127_3203412_0	285535.JOEY01000056_gene6770	1.243e-133	433.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria	201174|Actinobacteria	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
SRR25158249_k127_3203691_3	1521187.JPIM01000150_gene460	1.494e-29	122.0	COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi,377BT@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158249_k127_3203691_1	526227.Mesil_1567	2.791e-64	230.0	COG1177@1|root,COG1177@2|Bacteria,1WI58@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type spermidine putrescine transport system, permease component II	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158249_k127_3203691_0	479434.Sthe_1277	8.446e-72	253.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi,27XNS@189775|Thermomicrobia	189775|Thermomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158249_k127_3203691_2	1499967.BAYZ01000026_gene1563	1.788e-62	227.0	COG0687@1|root,COG0687@2|Bacteria,2NPSD@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158249_k127_3205297_2	1137268.AZXF01000005_gene3168	2.993e-24	104.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4EH9B@85012|Streptosporangiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158249_k127_3205297_1	324602.Caur_2890	1.71e-67	244.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi,376P6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158249_k127_3205297_0	326427.Cagg_3388	1.13e-108	362.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158249_k127_3205297_3	290397.Adeh_2985	8.607e-09	63.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.64	ko:K00852,ko:K19517	ko00030,ko00562,ko01100,map00030,map00562,map01100	-	R01051,R02750,R07279	RC00002,RC00017,RC00078	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158249_k127_3214338_2	395961.Cyan7425_0602	4.308e-10	70.0	COG5295@1|root,COG5295@2|Bacteria,1GF95@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
SRR25158249_k127_3214338_0	861299.J421_5675	2.077e-90	302.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158249_k127_3214338_1	390989.JOEG01000004_gene3918	7.272e-13	77.0	2F707@1|root,33ZG0@2|Bacteria,2IMY5@201174|Actinobacteria,4DF88@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3230621_3	525904.Tter_0716	3.667e-45	168.0	COG0088@1|root,COG0088@2|Bacteria,2NPF3@2323|unclassified Bacteria	2|Bacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02926,ko:K16193	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158249_k127_3230621_6	2423.NA23_0208195	6.651e-12	75.0	COG0089@1|root,COG0089@2|Bacteria,2GDJ8@200918|Thermotogae	200918|Thermotogae	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158249_k127_3230621_0	1121472.AQWN01000002_gene2043	5.704e-117	388.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,260NI@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158249_k127_3230621_4	525904.Tter_0719	9.924e-41	151.0	COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158249_k127_3230621_5	644966.Tmar_2290	2.591e-28	120.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WCKJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158249_k127_3230621_1	1341151.ASZU01000021_gene1299	5.897e-74	257.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,27BGQ@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal protein S3, C-terminal domain	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158249_k127_3230621_2	1382304.JNIL01000001_gene1958	7.46e-50	184.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,278B2@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158249_k127_3231040_3	1122221.JHVI01000006_gene2396	3.706e-24	105.0	COG4112@1|root,COG4112@2|Bacteria,1WMU8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158249_k127_3231040_1	309801.trd_1267	3.888e-70	255.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158249_k127_3231040_0	926569.ANT_29010	7.318e-91	309.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158249_k127_3231040_2	326427.Cagg_0842	1.32e-52	199.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
SRR25158249_k127_3234083_2	1312959.KI914673_gene3349	0.0001612	50.0	COG3794@1|root,COG3794@2|Bacteria,2GS7W@201174|Actinobacteria	201174|Actinobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158249_k127_3234083_0	536227.CcarbDRAFT_4777	1.438e-72	252.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR25158249_k127_3234083_1	1048339.KB913029_gene1655	7.65e-24	108.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4ESTA@85013|Frankiales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_3237125_0	485913.Krac_10277	3.64e-32	129.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158249_k127_3237125_1	877420.ATVW01000019_gene24	1.387e-06	61.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,27K7J@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158249_k127_3237125_2	1121405.dsmv_0998	5.968e-06	55.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria,2MK90@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158249_k127_3252679_0	401526.TcarDRAFT_1254	2.856e-100	336.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158249_k127_3252679_2	326427.Cagg_1724	1.739e-72	258.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia	32061|Chloroflexia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158249_k127_3252679_1	1121430.JMLG01000001_gene2276	9.435e-85	305.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25ZY0@186807|Peptococcaceae	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158249_k127_3252679_3	682795.AciX8_4439	9.575e-41	153.0	COG0537@1|root,COG0537@2|Bacteria,3Y542@57723|Acidobacteria,2JJT8@204432|Acidobacteriia	204432|Acidobacteriia	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158249_k127_3252679_4	35754.JNYJ01000002_gene6888	7.062e-30	126.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4D99Q@85008|Micromonosporales	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158249_k127_3258948_2	383372.Rcas_0257	2.642e-25	121.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,3764J@32061|Chloroflexia	32061|Chloroflexia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158249_k127_3258948_0	479434.Sthe_0414	1.228e-103	361.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia	189775|Thermomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158249_k127_3258948_1	68223.JNZY01000043_gene6041	5.357e-50	179.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158249_k127_3260948_4	633148.Tagg_0923	1.873e-09	65.0	COG1983@1|root,arCOG03456@2157|Archaea	2157|Archaea	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR25158249_k127_3260948_5	555088.DealDRAFT_2728	6.41e-07	61.0	COG4758@1|root,COG4758@2|Bacteria,1UITP@1239|Firmicutes,24NAQ@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
SRR25158249_k127_3260948_0	369723.Strop_3972	8.416e-49	182.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4DC3H@85008|Micromonosporales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158249_k127_3260948_2	56107.Cylst_3878	9.427e-22	104.0	COG0204@1|root,COG0204@2|Bacteria,1G1AK@1117|Cyanobacteria,1HMFN@1161|Nostocales	1117|Cyanobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158249_k127_3260948_3	465541.ATCJ01000005_gene6953	1.512e-18	97.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria	201174|Actinobacteria	H	Pfam UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158249_k127_3260948_1	1028800.RG540_CH40330	2.542e-42	169.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,4B7NP@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158249_k127_3260948_6	706434.HMPREF9429_00128	6.381e-05	46.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H331@909932|Negativicutes	909932|Negativicutes	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158249_k127_3278446_1	316274.Haur_4475	2.583e-75	261.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,374YX@32061|Chloroflexia	32061|Chloroflexia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158249_k127_3278446_0	357808.RoseRS_0794	6.11e-114	390.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi,375DT@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158249_k127_328399_4	690585.JNNU01000008_gene3594	3.397e-24	105.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158249_k127_328399_6	1121918.ARWE01000001_gene3170	7.224e-11	75.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SRR25158249_k127_328399_2	390989.JOEG01000026_gene1548	2.811e-32	134.0	COG1670@1|root,COG1670@2|Bacteria,2GMDB@201174|Actinobacteria,4DAZM@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_328399_5	402626.Rpic_2309	1.571e-14	80.0	2EMWV@1|root,33FJ4@2|Bacteria,1NI97@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_328399_0	1128421.JAGA01000003_gene2793	2.822e-46	171.0	COG2236@1|root,COG2236@2|Bacteria	2|Bacteria	F	xanthine phosphoribosyltransferase activity	gpt	GO:0000310,GO:0003674,GO:0003824,GO:0004422,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0032265,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22	ko:K00769,ko:K07101	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iSbBS512_1146.SbBS512_E0235	Pribosyltran
SRR25158249_k127_328399_1	365528.KB891225_gene1191	8.689e-40	154.0	2EQ60@1|root,33HSB@2|Bacteria,2GPNC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_328399_3	298655.KI912266_gene3516	1.633e-26	119.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	marR5	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRR25158249_k127_3289708_0	525904.Tter_0028	3.043e-91	312.0	COG1351@1|root,COG1351@2|Bacteria,2NQ7P@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158249_k127_3289708_1	717605.Theco_1937	9.895e-84	287.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158249_k127_3299208_3	1218075.BAYA01000012_gene3659	0.0002383	48.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1K707@119060|Burkholderiaceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158249_k127_3299208_0	300852.55773149	1.665e-89	308.0	COG0825@1|root,COG0825@2|Bacteria,1WJ82@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158249_k127_3299208_1	338963.Pcar_0737	9.614e-89	304.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,43S80@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158249_k127_3299208_2	469383.Cwoe_1762	8.502e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,2HG39@201174|Actinobacteria,4CP8K@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_3324928_2	118163.Ple7327_4530	8.468e-09	60.0	COG0784@1|root,COG2202@1|root,COG3852@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,3VHZD@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
SRR25158249_k127_3324928_3	1323361.JPOC01000037_gene4170	0.0002651	49.0	COG2867@1|root,COG2867@2|Bacteria,2IEZI@201174|Actinobacteria,4G3A6@85025|Nocardiaceae	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158249_k127_3324928_1	1463825.JNXC01000023_gene4897	3.974e-97	327.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4DYI7@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158249_k127_3324928_0	696747.NIES39_C00970	1.01e-99	349.0	COG0513@1|root,COG0513@2|Bacteria,1G0VD@1117|Cyanobacteria,1H785@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032574,GO:0032575,GO:0033592,GO:0034057,GO:0034458,GO:0034459,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158249_k127_3335520_2	1382356.JQMP01000003_gene2497	3.615e-33	139.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,27XW5@189775|Thermomicrobia	189775|Thermomicrobia	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158249_k127_3335520_1	1265503.KB905165_gene1265	1.325e-186	594.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	iECO26_1355.ECO26_5036,iPC815.YPO4038	-
SRR25158249_k127_3335520_0	926569.ANT_24910	1.718e-198	629.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_3366886_3	663278.Ethha_0427	2.089e-05	57.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158249_k127_3366886_2	926550.CLDAP_23120	1.533e-38	164.0	COG1349@1|root,COG1349@2|Bacteria,2G6FT@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158249_k127_3366886_0	926569.ANT_03990	1.471e-80	283.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi	200795|Chloroflexi	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	lacD	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158249_k127_3366886_1	1463820.JOGW01000008_gene1735	6.322e-59	217.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria	201174|Actinobacteria	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158249_k127_3369164_2	525904.Tter_1028	4.162e-52	195.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314,ko:K02316,ko:K17680	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DnaB_C,Toprim_2,Toprim_N,zf-CHC2
SRR25158249_k127_3369164_0	525904.Tter_0214	5.283e-146	478.0	COG0624@1|root,COG0624@2|Bacteria,2NQM8@2323|unclassified Bacteria	2|Bacteria	E	Peptidase dimerisation domain	dapE	-	3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158249_k127_3369164_1	1382356.JQMP01000003_gene2325	5.403e-71	246.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,27XT6@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SRR25158249_k127_3369966_3	1120959.ATXF01000009_gene752	1.01e-19	92.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4FS0V@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158249_k127_3369966_0	1125971.ASJB01000069_gene391	1.016e-108	367.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DZF1@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158249_k127_3369966_2	1464048.JNZS01000002_gene344	3.05e-67	236.0	COG0842@1|root,COG0842@2|Bacteria,2GJ2G@201174|Actinobacteria,4DDT9@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158249_k127_3369966_1	345341.KUTG_07330	5.217e-99	327.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXBN@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_3381692_0	255470.cbdbA738	1.668e-199	638.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi,34CNJ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158249_k127_3381692_1	1157490.EL26_18425	1.812e-34	142.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli	91061|Bacilli	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158249_k127_3389997_1	292459.STH1934	6.352e-11	68.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158249_k127_3389997_0	926569.ANT_02530	5.958e-50	194.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158249_k127_3392968_0	1507.HMPREF0262_02629	6.53e-56	201.0	COG1957@1|root,COG1957@2|Bacteria,1VUDG@1239|Firmicutes,250GA@186801|Clostridia,36RQ9@31979|Clostridiaceae	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
SRR25158249_k127_3392968_1	1128421.JAGA01000002_gene1633	2.942e-31	132.0	arCOG08811@1|root,32UTS@2|Bacteria,2NR80@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3392968_2	1157637.KB892093_gene6721	1.082e-13	82.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158249_k127_3396911_3	1499967.BAYZ01000013_gene6452	2.015e-75	265.0	COG2227@1|root,COG2227@2|Bacteria,2NRF7@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158249_k127_3396911_0	680198.SCAB_12451	2.578e-150	488.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria	201174|Actinobacteria	F	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158249_k127_3396911_2	351607.Acel_1045	7.796e-77	270.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4EWCI@85013|Frankiales	201174|Actinobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158249_k127_3396911_1	1172188.KB911828_gene4081	1.553e-112	368.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4FIX9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158249_k127_3400580_0	189426.PODO_03220	4.539e-33	147.0	COG5650@1|root,COG5650@2|Bacteria,1UIQG@1239|Firmicutes,4ISQB@91061|Bacilli,2776M@186822|Paenibacillaceae	91061|Bacilli	S	Pfam:DUF2029	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PIG-U
SRR25158249_k127_3400580_1	1192034.CAP_6141	1.232e-10	73.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3407052_1	399739.Pmen_1735	1.268e-23	103.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1YF5S@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_2673	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158249_k127_3407052_0	1382306.JNIM01000001_gene1379	5.698e-70	249.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158249_k127_340770_0	298655.KI912266_gene6560	7.151e-117	386.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4EUWY@85013|Frankiales	201174|Actinobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158249_k127_340770_3	1382356.JQMP01000003_gene2347	4.214e-27	123.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,27Y5W@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158249_k127_340770_2	1449126.JQKL01000003_gene1792	1.901e-38	159.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia	186801|Clostridia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
SRR25158249_k127_340770_1	266117.Rxyl_1602	3.721e-59	225.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158249_k127_3421361_0	479434.Sthe_3017	2.789e-50	194.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,27YF9@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158249_k127_3421361_1	1395513.P343_09025	2.197e-13	78.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,26PES@186821|Sporolactobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158249_k127_3447313_2	1470593.BW43_05368	4.603e-18	88.0	COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,1S8B3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	protocatechuate 3,4-dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158249_k127_3447313_1	1411123.JQNH01000001_gene2070	7.704e-108	365.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protocatechuate 3,4-dioxygenase, beta subunit'	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRR25158249_k127_3447313_0	1144319.PMI16_04573	2.219e-110	359.0	COG2057@1|root,COG2057@2|Bacteria,1MWW1@1224|Proteobacteria,2VIBE@28216|Betaproteobacteria,473D5@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Coenzyme A transferase	pcaJ	-	2.8.3.6	ko:K01032	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158249_k127_3460264_0	66377.JOBH01000031_gene4502	6.675e-193	615.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158249_k127_3478781_1	718252.FP2_30260	6.732e-16	85.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WJZN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158249_k127_3478781_0	380749.HY04AAS1_1012	6.781e-103	346.0	COG0532@1|root,COG0532@2|Bacteria,2G3W1@200783|Aquificae	200783|Aquificae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158249_k127_3486827_2	706433.HMPREF9430_01074	6.257e-23	102.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,3VPJM@526524|Erysipelotrichia	526524|Erysipelotrichia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	-	-	-	-	-	-	-	-	-	-	Indigoidine_A
SRR25158249_k127_3486827_0	1128421.JAGA01000003_gene3395	1.305e-99	337.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158249_k127_3486827_1	926569.ANT_06950	3.597e-75	263.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158249_k127_3486827_3	926569.ANT_06940	6.005e-13	81.0	COG0842@1|root,COG0842@2|Bacteria,2G8MV@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158249_k127_3487382_2	555088.DealDRAFT_0941	3.776e-21	101.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158249_k127_3487382_1	1304875.JAFZ01000001_gene1078	2.633e-29	130.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158249_k127_3487382_0	1128421.JAGA01000003_gene2953	1.297e-37	155.0	COG0366@1|root,COG0366@2|Bacteria,2NQQN@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158249_k127_3489353_1	765420.OSCT_1709	3.774e-05	56.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi,375CV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3489353_0	1303518.CCALI_01483	2.489e-05	53.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.5	ko:K00848,ko:K00851,ko:K00854	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
SRR25158249_k127_3491301_0	106370.Francci3_2946	2.579e-112	372.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4ERQN@85013|Frankiales	201174|Actinobacteria	C	PFAM alanine dehydrogenase PNT domain protein	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158249_k127_3491301_1	1137269.AZWL01000002_gene6540	1.652e-35	146.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria	201174|Actinobacteria	C	NADP transhydrogenase	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158249_k127_3491301_2	106370.Francci3_2948	7.11e-32	137.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4ERWF@85013|Frankiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158249_k127_3494396_0	1172188.KB911821_gene1806	1.219e-245	773.0	COG1452@1|root,COG1452@2|Bacteria,2GNM6@201174|Actinobacteria,4FF8Z@85021|Intrasporangiaceae	201174|Actinobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRR25158249_k127_3495119_0	420246.GTNG_2709	1.392e-117	393.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1WEHU@129337|Geobacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158249_k127_3505733_1	420324.KI912052_gene6123	9.981e-41	157.0	COG0500@1|root,COG0500@2|Bacteria,1RCP3@1224|Proteobacteria,2TXSH@28211|Alphaproteobacteria,1JT07@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3505733_0	1382306.JNIM01000001_gene535	3.307e-52	193.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158249_k127_3522026_0	743718.Isova_2798	9.437e-56	215.0	COG0308@1|root,COG0308@2|Bacteria,2ID1N@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3522026_1	1894.JOER01000095_gene6	3.248e-15	81.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158249_k127_3535148_2	1521187.JPIM01000101_gene3500	1.72e-13	84.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,37570@32061|Chloroflexia	32061|Chloroflexia	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158249_k127_3535148_1	357808.RoseRS_3160	2.911e-59	221.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158249_k127_3535148_0	383372.Rcas_0210	1.175e-135	440.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158249_k127_3554641_2	1122622.ATWJ01000012_gene992	6.494e-39	153.0	COG3896@1|root,COG3896@2|Bacteria,2IFF0@201174|Actinobacteria	201174|Actinobacteria	V	chloramphenicol	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
SRR25158249_k127_3554641_1	867845.KI911784_gene3657	5.577e-74	257.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158249_k127_3554641_0	1120950.KB892770_gene1376	4.567e-88	310.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4DNBF@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158249_k127_3554641_3	290397.Adeh_1832	2.09e-11	65.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,2YV7A@29|Myxococcales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158249_k127_3569063_1	525904.Tter_1872	4.666e-152	490.0	COG1239@1|root,COG1239@2|Bacteria,2NQQG@2323|unclassified Bacteria	2|Bacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
SRR25158249_k127_3569063_0	479434.Sthe_3486	1.331e-195	632.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3569063_2	379066.GAU_1107	3.464e-118	392.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158249_k127_3570268_2	356851.JOAN01000033_gene1823	6.118e-80	285.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4DB92@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158249_k127_3570268_1	263358.VAB18032_20120	1.366e-83	289.0	COG0745@1|root,COG0745@2|Bacteria,2GJRR@201174|Actinobacteria,4DCMD@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_3570268_3	357808.RoseRS_0308	1.772e-17	96.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,377H1@32061|Chloroflexia	32061|Chloroflexia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158249_k127_3570268_0	986075.CathTA2_2343	5.204e-146	473.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158249_k127_3574116_2	1382306.JNIM01000001_gene1633	1.443e-64	230.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_3574116_3	419947.MRA_3732	1.475e-40	154.0	COG1848@1|root,COG1848@2|Bacteria,2IPKR@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158249_k127_3574116_5	862967.SIR_1169	1.124e-08	63.0	2DPVQ@1|root,333KH@2|Bacteria,1VJVD@1239|Firmicutes,4I10J@91061|Bacilli	91061|Bacilli	S	zinc-ribbon family	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_15
SRR25158249_k127_3574116_0	298655.KI912266_gene1982	5.151e-152	489.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4ERS8@85013|Frankiales	201174|Actinobacteria	E	aminotransferase class I and II	-	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K10907,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158249_k127_3574116_4	1487953.JMKF01000095_gene5150	4.197e-16	79.0	COG0745@1|root,COG2909@1|root,COG0745@2|Bacteria,COG2909@2|Bacteria,1G39U@1117|Cyanobacteria,1HG05@1150|Oscillatoriales	1117|Cyanobacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3574116_1	196490.AUEZ01000013_gene4734	2.751e-146	482.0	COG0745@1|root,COG2909@1|root,COG0745@2|Bacteria,COG2909@2|Bacteria,1N5KV@1224|Proteobacteria,2U9X6@28211|Alphaproteobacteria,3K38Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158249_k127_358862_2	1274374.CBLK010000083_gene3786	2.954e-73	251.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4HAQY@91061|Bacilli,26UJE@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158249_k127_358862_1	1195236.CTER_2825	7.437e-81	283.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3WH9G@541000|Ruminococcaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
SRR25158249_k127_358862_0	926550.CLDAP_27330	8.508e-97	327.0	COG1609@1|root,COG1609@2|Bacteria,2G6BD@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158249_k127_358862_5	383372.Rcas_4129	4.796e-15	89.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158249_k127_358862_4	1121423.JONT01000010_gene1803	1.695e-20	100.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,262RC@186807|Peptococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158249_k127_358862_3	935866.JAER01000021_gene829	3.072e-47	184.0	COG2133@1|root,COG2133@2|Bacteria,2HUAS@201174|Actinobacteria,4DSK7@85009|Propionibacteriales	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_358862_6	1245471.PCA10_30640	1.899e-14	75.0	COG3025@1|root,COG3025@2|Bacteria	2|Bacteria	S	triphosphatase activity	ygiF	-	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
SRR25158249_k127_3596168_0	1463861.JNXE01000002_gene6296	8.646e-153	492.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158249_k127_3597907_0	1306174.JODP01000006_gene3483	3.844e-87	317.0	COG3899@1|root,COG5001@1|root,COG3899@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_8,PAS_9
SRR25158249_k127_3600137_3	103733.JNYO01000001_gene190	6.107e-06	49.0	COG1409@1|root,COG1409@2|Bacteria,2GIT1@201174|Actinobacteria,4E0S4@85010|Pseudonocardiales	201174|Actinobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158249_k127_3600137_0	1122611.KB904029_gene5414	4.957e-304	953.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4EFY3@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158249_k127_3600137_2	465541.ATCJ01000005_gene5253	1.356e-62	228.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria	201174|Actinobacteria	G	inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158249_k127_3600137_1	1382356.JQMP01000004_gene326	6.174e-83	284.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,27XJH@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158249_k127_3603381_0	1169161.KB897725_gene1732	8.635e-92	314.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158249_k127_3603381_1	1089455.MOPEL_074_00830	1.077e-24	114.0	COG1333@1|root,COG1333@2|Bacteria,2I0CQ@201174|Actinobacteria,4F61R@85018|Dermatophilaceae	201174|Actinobacteria	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
SRR25158249_k127_3612718_1	1075090.GOAMR_19_00480	2.285e-25	119.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4GBZS@85026|Gordoniaceae	201174|Actinobacteria	T	Universal stress protein family	uspA1	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158249_k127_3612718_0	290397.Adeh_0965	1.854e-125	409.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
SRR25158249_k127_3614126_0	298654.FraEuI1c_1072	1.038e-16	81.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4ESKU@85013|Frankiales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158249_k127_3614126_1	196367.JNFG01000024_gene8110	1e-08	68.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,1JZPI@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158249_k127_3614985_4	388399.SSE37_01495	0.0006487	51.0	COG1396@1|root,COG1396@2|Bacteria,1N8D1@1224|Proteobacteria,2UA7K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158249_k127_3614985_3	561175.KB894093_gene3244	3.198e-10	72.0	COG1277@1|root,COG1277@2|Bacteria,2GM0N@201174|Actinobacteria,4EHCP@85012|Streptosporangiales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158249_k127_3614985_0	1089545.KB913037_gene2054	1.173e-54	203.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4DZCH@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_3614985_2	485913.Krac_3333	1.104e-24	120.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_4,PAS_9
SRR25158249_k127_3614985_1	479433.Caci_8900	1.043e-29	134.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158249_k127_3626284_1	383372.Rcas_3982	3.576e-05	52.0	COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158249_k127_3626284_0	1380356.JNIK01000014_gene3482	2.376e-82	296.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158249_k127_3628293_1	1118054.CAGW01000048_gene1617	1.185e-17	87.0	COG0454@1|root,COG0456@2|Bacteria,1V40T@1239|Firmicutes,4HI2H@91061|Bacilli,26YNM@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_3628293_2	56780.SYN_02280	2.081e-17	90.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,43B7B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158249_k127_3628293_0	861299.J421_3175	1.806e-133	436.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158249_k127_3629643_2	1382356.JQMP01000003_gene2578	2.529e-13	80.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158249_k127_3629643_1	264732.Moth_1028	4.437e-68	243.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42HMW@68295|Thermoanaerobacterales	186801|Clostridia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158249_k127_3629643_0	765912.Thimo_1256	5.338e-90	310.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
SRR25158249_k127_3655329_3	1408423.JHYA01000014_gene339	3.189e-13	80.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4H3B5@909932|Negativicutes	909932|Negativicutes	E	family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158249_k127_3655329_0	1382306.JNIM01000001_gene664	2.728e-121	409.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1e
SRR25158249_k127_3655329_2	1382306.JNIM01000001_gene1358	1.497e-30	134.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158249_k127_3655329_1	1298863.AUEP01000009_gene171	8.542e-51	183.0	2DB71@1|root,2Z7JE@2|Bacteria,2I2SN@201174|Actinobacteria	201174|Actinobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158249_k127_366133_1	1267535.KB906767_gene3861	1.091e-21	102.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
SRR25158249_k127_366133_2	69781.S8B8U9	0.0003381	48.0	2E1K8@1|root,2S8X0@2759|Eukaryota,3A88T@33154|Opisthokonta,3P7TG@4751|Fungi,3QYHF@4890|Ascomycota,20IB8@147545|Eurotiomycetes,3S9FY@5042|Eurotiales	4751|Fungi	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRR25158249_k127_366133_0	42256.RradSPS_2843	2.283e-64	232.0	COG0346@1|root,COG0346@2|Bacteria,2H18J@201174|Actinobacteria	201174|Actinobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3664972_0	562970.Btus_0196	6.869e-55	205.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,2781N@186823|Alicyclobacillaceae	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158249_k127_3664972_1	1095750.HMPREF9970_0609	5.604e-05	53.0	COG4856@1|root,COG4856@2|Bacteria,1UY6U@1239|Firmicutes,25CGJ@186801|Clostridia,1HUVN@1164882|Lachnoanaerobaculum	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158249_k127_3667282_1	1463853.JOHW01000013_gene3774	5.827e-86	321.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria	201174|Actinobacteria	E	Acetylornithine deacetylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158249_k127_3667282_2	309801.trd_1282	7.482e-61	227.0	COG1834@1|root,COG1834@2|Bacteria,2G7QT@200795|Chloroflexi,27YZU@189775|Thermomicrobia	189775|Thermomicrobia	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158249_k127_3667282_0	526227.Mesil_2489	5.773e-102	350.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158249_k127_3670872_3	292459.STH2564	4.74e-13	77.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
SRR25158249_k127_3670872_0	42256.RradSPS_0432	6.576e-86	306.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4CQ6X@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_3670872_2	1279038.KB907347_gene3155	4.927e-17	94.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,2JTRF@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRR25158249_k127_3670872_1	309801.trd_0409	2.047e-26	118.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,27Z5W@189775|Thermomicrobia	189775|Thermomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158249_k127_3693735_0	926569.ANT_05580	3.71e-36	152.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158249_k127_3693735_1	1283299.AUKG01000001_gene1783	9.213e-23	111.0	COG0628@1|root,COG0628@2|Bacteria,2HGG6@201174|Actinobacteria,4CQ8P@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158249_k127_3698125_1	1121468.AUBR01000033_gene1208	6.838e-18	96.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,42EU1@68295|Thermoanaerobacterales	186801|Clostridia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158249_k127_3698125_0	351348.Maqu_0815	1.114e-19	101.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,464IT@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158249_k127_3698125_2	867903.ThesuDRAFT_02026	4.202e-09	59.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WCR7@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158249_k127_3731806_0	298653.Franean1_3187	9.528e-191	609.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158249_k127_373979_4	479432.Sros_9352	2.84e-11	66.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4EGKS@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,DUF2808,SBP_bac_3
SRR25158249_k127_373979_0	390989.JOEG01000009_gene924	1.586e-102	342.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DAT6@85008|Micromonosporales	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158249_k127_373979_3	584708.Apau_2184	3.872e-31	132.0	COG2071@1|root,COG2071@2|Bacteria,3TB4C@508458|Synergistetes	508458|Synergistetes	S	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158249_k127_373979_2	644966.Tmar_0739	7.088e-33	149.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
SRR25158249_k127_373979_1	525904.Tter_0442	1.851e-37	164.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,PilZ,Response_reg
SRR25158249_k127_3801025_3	1123258.AQXZ01000017_gene3815	5.203e-29	122.0	COG1819@1|root,COG1819@2|Bacteria,2GKKY@201174|Actinobacteria,4G3IR@85025|Nocardiaceae	201174|Actinobacteria	CG	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase	-	-	-	ko:K15929	ko01057,ko01130,map01057,map01130	-	R06670	RC00171	ko00000,ko00001,ko01000	-	GT1	-	DUF1205,UDPGT
SRR25158249_k127_3801025_0	1031288.AXAA01000005_gene2057	1.059e-126	423.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,36E7R@31979|Clostridiaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158249_k127_3801025_4	324602.Caur_0310	4.664e-12	71.0	2A4D2@1|root,30SYV@2|Bacteria,2G7DH@200795|Chloroflexi,377NP@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158249_k127_3801025_1	1449351.RISW2_15235	3.72e-115	383.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,4KMCS@93682|Roseivivax	28211|Alphaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158249_k127_3801025_2	266117.Rxyl_1423	1.776e-37	145.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158249_k127_3803871_1	1121946.AUAX01000011_gene4124	3.419e-77	272.0	COG1879@1|root,COG1879@2|Bacteria,2I43Z@201174|Actinobacteria,4DB0T@85008|Micromonosporales	201174|Actinobacteria	G	ABC-type sugar transport system, periplasmic component	rhaS	-	-	ko:K02058,ko:K10559	ko02010,map02010	M00220,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.9	-	-	Peripla_BP_4
SRR25158249_k127_3803871_0	1382306.JNIM01000001_gene25	2.43e-104	351.0	COG1172@1|root,COG1172@2|Bacteria,2G6DF@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
SRR25158249_k127_3812103_1	457570.Nther_2188	1.261e-71	266.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158249_k127_3812103_0	552811.Dehly_1315	1.647e-97	336.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi,34CXV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Beta-eliminating lyase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158249_k127_3812103_3	272952.HpaP804666	1.068e-12	80.0	2CP2U@1|root,2QZM8@2759|Eukaryota,3QABV@4776|Peronosporales	4776|Peronosporales	S	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158249_k127_3812103_2	765420.OSCT_2672	1.237e-35	152.0	COG0628@1|root,COG0628@2|Bacteria,2G712@200795|Chloroflexi,375FE@32061|Chloroflexia	32061|Chloroflexia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158249_k127_3815747_0	1382306.JNIM01000001_gene3339	1.02e-200	637.0	COG0129@1|root,COG0129@2|Bacteria,2G67Z@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158249_k127_3819464_2	1123269.NX02_06095	1.239e-12	70.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria,2K0E1@204457|Sphingomonadales	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158249_k127_3819464_1	375286.mma_3209	1.361e-28	123.0	COG3495@1|root,COG3495@2|Bacteria,1RFBI@1224|Proteobacteria,2VRJ9@28216|Betaproteobacteria,477HV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
SRR25158249_k127_3819464_0	97096.XP_007790920.1	2.892e-149	494.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158249_k127_3824379_2	591158.SSMG_04656	1.568e-07	54.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria	201174|Actinobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158249_k127_3824379_0	1382356.JQMP01000004_gene506	5.2e-84	304.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158249_k127_3824379_1	1032480.MLP_07960	8.155e-12	78.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158249_k127_3826761_0	479435.Kfla_2107	3.802e-211	697.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2IAS1@201174|Actinobacteria,4DWMF@85009|Propionibacteriales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
SRR25158249_k127_3826761_3	1085623.GNIT_3166	3.751e-05	55.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,466GU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158249_k127_3826761_2	292459.STH174	1.98e-25	111.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR25158249_k127_3826761_1	477641.MODMU_4593	1.886e-36	143.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158249_k127_3832867_1	869210.Marky_1332	1.992e-38	150.0	COG3842@1|root,COG3842@2|Bacteria,1WIB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158249_k127_3832867_0	429009.Adeg_0447	8.143e-39	156.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158249_k127_3832867_2	1449976.KALB_801	1.079e-12	75.0	COG0457@1|root,COG0457@2|Bacteria,2I3MN@201174|Actinobacteria,4E4BA@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158249_k127_3835648_4	926556.Echvi_1086	0.0004156	47.0	2DT41@1|root,33IK2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3835648_2	1254432.SCE1572_09945	6.316e-85	312.0	COG5555@1|root,COG5555@2|Bacteria,1QX82@1224|Proteobacteria,43CYG@68525|delta/epsilon subdivisions,2X86M@28221|Deltaproteobacteria,2Z3M6@29|Myxococcales	28221|Deltaproteobacteria	N	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
SRR25158249_k127_3835648_1	1459636.NTE_00699	1.014e-88	315.0	COG3391@1|root,arCOG02562@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,FG-GAP_2
SRR25158249_k127_3835648_0	484770.UFO1_1284	1.022e-230	726.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes	909932|Negativicutes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158249_k127_3835648_3	485913.Krac_8967	2.163e-35	141.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158249_k127_3845020_2	1382306.JNIM01000001_gene3765	1.792e-32	135.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158249_k127_3845020_1	1278073.MYSTI_07208	1.377e-49	184.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158249_k127_3845020_0	1382356.JQMP01000003_gene2153	9.933e-54	200.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XV7@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158249_k127_3850219_0	485913.Krac_11273	1.025e-145	466.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
SRR25158249_k127_3850219_1	326427.Cagg_1437	2.305e-57	218.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3757Z@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158249_k127_3851745_3	1048339.KB913029_gene1655	1.586e-18	94.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4ESTA@85013|Frankiales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_3851745_2	1457250.BBMO01000002_gene2439	1.915e-23	115.0	COG1305@1|root,arCOG02169@2157|Archaea,2XU51@28890|Euryarchaeota,23SBW@183963|Halobacteria	183963|Halobacteria	E	COG1305 Transglutaminase-like enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158249_k127_3851745_1	479434.Sthe_3033	1.438e-45	179.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158249_k127_3851745_0	1906.SFRA_31355	1.447e-130	436.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158249_k127_3851745_4	1132855.KB913035_gene158	3.42e-13	71.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VQJU@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158249_k127_3852129_6	1050202.KB913024_gene1841	4.809e-13	71.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,407P2@622450|Actinopolysporales	201174|Actinobacteria	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158249_k127_3852129_1	326427.Cagg_1997	1.491e-116	401.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi,376PG@32061|Chloroflexia	32061|Chloroflexia	GM	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158249_k127_3852129_8	1122138.AQUZ01000007_gene3134	9.226e-08	61.0	COG4767@1|root,COG4767@2|Bacteria,2IRNR@201174|Actinobacteria	201174|Actinobacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158249_k127_3852129_3	926560.KE387023_gene2070	3.487e-38	158.0	COG0463@1|root,COG0463@2|Bacteria,1WNH4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158249_k127_3852129_9	1158292.JPOE01000002_gene1483	7.216e-05	55.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2VQVJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	2-epimerase	-	-	3.2.1.183,3.2.1.184,5.1.3.14	ko:K01791,ko:K08068,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158249_k127_3852129_4	1184609.KILIM_001_00380	1.399e-34	141.0	COG2120@1|root,COG2120@2|Bacteria,2GTU6@201174|Actinobacteria	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3852129_0	864702.OsccyDRAFT_3398	1.516e-185	595.0	COG0028@1|root,COG0028@2|Bacteria,1G0KQ@1117|Cyanobacteria,1H8HU@1150|Oscillatoriales	1117|Cyanobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158249_k127_3852129_5	416348.Hlac_0128	8.277e-17	89.0	COG0681@1|root,arCOG01739@2157|Archaea,2XX34@28890|Euryarchaeota,23VYJ@183963|Halobacteria	183963|Halobacteria	U	COG0681 Signal peptidase I	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158249_k127_3852129_7	1304865.JAGF01000001_gene800	1.699e-11	73.0	2ET2U@1|root,33KKZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M73
SRR25158249_k127_3852129_2	1268622.AVS7_04106	1.627e-88	319.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,4ACFB@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158249_k127_3880711_0	357808.RoseRS_1455	2.324e-100	339.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,374W3@32061|Chloroflexia	32061|Chloroflexia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158249_k127_3880711_2	1380347.JNII01000011_gene909	4.041e-57	221.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4ESDU@85013|Frankiales	201174|Actinobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158249_k127_3880711_1	1038858.AXBA01000001_gene3229	1.942e-93	319.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3EYYC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158249_k127_390201_1	272134.KB731324_gene4425	8.421e-08	55.0	COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,1H7R9@1150|Oscillatoriales	2|Bacteria	S	COGs COG1432 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158249_k127_390201_0	1382306.JNIM01000001_gene1703	1.848e-47	181.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158249_k127_3909638_5	509635.N824_09425	0.0007204	44.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1IRW6@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158249_k127_3909638_3	66875.JODY01000041_gene1908	2.453e-66	235.0	COG0384@1|root,COG0384@2|Bacteria,2GMX1@201174|Actinobacteria	201174|Actinobacteria	S	Phenazine biosynthesis PhzC PhzF protein	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158249_k127_3909638_4	591167.Sfla_2940	7.266e-07	57.0	COG2208@1|root,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,PAS_4,SpoIIE
SRR25158249_k127_3909638_0	247639.MGP2080_02481	4.348e-124	410.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JBXZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158249_k127_3909638_1	1122609.AUGT01000009_gene3341	2.301e-96	334.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4DRYR@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158249_k127_3909638_2	1122609.AUGT01000009_gene3347	3.128e-96	340.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4DPH8@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158249_k127_3920624_11	235985.BBPN01000030_gene2017	1.503e-42	181.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,2NHGH@228398|Streptacidiphilus	201174|Actinobacteria	F	Glutamine amidotransferase domain	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158249_k127_3920624_0	469371.Tbis_3339	3.542e-197	652.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DXHH@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158249_k127_3920624_9	266117.Rxyl_0995	2.653e-70	251.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4CPW1@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158249_k127_3920624_14	1033730.CAHG01000008_gene3086	2.981e-13	81.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158249_k127_3920624_6	1380390.JIAT01000009_gene1486	1.427e-103	349.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CPBJ@84995|Rubrobacteria	84995|Rubrobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158249_k127_3920624_1	477974.Daud_1634	7.481e-140	462.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158249_k127_3920624_4	391165.GbCGDNIH1_2297	4.412e-107	362.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2JPEF@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158249_k127_3920624_2	644966.Tmar_2349	5.429e-137	455.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WCYT@538999|Clostridiales incertae sedis	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158249_k127_3920624_15	1449065.JMLL01000002_gene3800	4.044e-06	51.0	COG0665@1|root,COG0665@2|Bacteria,1PHYQ@1224|Proteobacteria,2VE6H@28211|Alphaproteobacteria,43Q6K@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158249_k127_3920624_7	1317124.DW2_03834	1.382e-94	334.0	COG4213@1|root,COG4213@2|Bacteria,1R4J2@1224|Proteobacteria,2TUHF@28211|Alphaproteobacteria,2XKYD@285107|Thioclava	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158249_k127_3920624_5	1417296.U879_18800	4.642e-104	346.0	COG1129@1|root,COG4214@1|root,COG1129@2|Bacteria,COG4214@2|Bacteria,1P3ZB@1224|Proteobacteria,2VET1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K02056,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran,BPD_transp_2
SRR25158249_k127_3920624_3	1101188.KI912155_gene3650	5.61e-125	414.0	COG1129@1|root,COG4214@1|root,COG1129@2|Bacteria,COG4214@2|Bacteria,2GJDV@201174|Actinobacteria,1W8CQ@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR25158249_k127_3920624_12	926569.ANT_22420	3.461e-25	113.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158249_k127_3920624_10	411684.HPDFL43_20412	2.029e-60	220.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,43H9M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158249_k127_3920624_8	926569.ANT_07770	2.864e-80	283.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158249_k127_3920624_13	671143.DAMO_2425	5.088e-21	97.0	COG0388@1|root,COG0388@2|Bacteria,2NQD8@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158249_k127_3921494_1	926550.CLDAP_13740	2.222e-05	56.0	2DRD4@1|root,33B9X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_3921494_0	1211115.ALIQ01000018_gene2131	1.087e-09	69.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,3NADE@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158249_k127_3921494_2	1048339.KB913029_gene3826	6.612e-05	46.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4ES6D@85013|Frankiales	201174|Actinobacteria	C	PFAM Aldehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158249_k127_3929817_1	1122138.AQUZ01000018_gene7522	1.347e-140	452.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4DV19@85009|Propionibacteriales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1,3.5.5.7	ko:K01501,ko:K01502	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05358,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC01336,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158249_k127_3929817_3	66373.JOFQ01000011_gene7028	7.142e-07	59.0	COG2337@1|root,COG2337@2|Bacteria,2IM6R@201174|Actinobacteria	201174|Actinobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158249_k127_3929817_0	479434.Sthe_1229	9.291e-157	515.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158249_k127_3929817_2	479434.Sthe_1230	3.215e-23	100.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158249_k127_3941875_3	479434.Sthe_2301	9.335e-21	103.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158249_k127_3941875_2	103733.JNYO01000042_gene6098	4.313e-35	145.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,2GMB5@201174|Actinobacteria,4E0F0@85010|Pseudonocardiales	201174|Actinobacteria	T	PNKP adenylyltransferase domain, ligase domain	prpA	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
SRR25158249_k127_3941875_0	443218.AS9A_3886	7.72e-107	359.0	COG0715@1|root,COG0715@2|Bacteria,2GK7X@201174|Actinobacteria,235U4@1762|Mycobacteriaceae	201174|Actinobacteria	P	NMT1-like family	ssuA3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158249_k127_3941875_1	1205910.B005_3987	6.144e-95	324.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EGCG@85012|Streptosporangiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ssuB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158249_k127_394895_0	1128421.JAGA01000002_gene991	1.519e-148	489.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158249_k127_394895_1	471857.Svir_31300	2.066e-30	128.0	COG1670@1|root,COG1670@2|Bacteria,2IKXU@201174|Actinobacteria,4E52E@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_3957655_1	1205680.CAKO01000006_gene3331	2.422e-82	292.0	COG5482@1|root,COG5482@2|Bacteria,1MWIN@1224|Proteobacteria,2TS4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	MA20_28540	-	-	-	-	-	-	-	-	-	-	-	DUF2161
SRR25158249_k127_3957655_5	1040983.AXAE01000001_gene2913	5.854e-42	174.0	COG0395@1|root,COG0395@2|Bacteria,1QHIK@1224|Proteobacteria,2U2IY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158249_k127_3957655_4	926560.KE387025_gene4108	9.301e-50	189.0	COG1175@1|root,COG1175@2|Bacteria,1WJI2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158249_k127_3957655_7	556261.HMPREF0240_00119	2.886e-21	108.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158249_k127_3957655_0	1304865.JAGF01000001_gene433	0.0	1086.0	COG2909@1|root,COG2909@2|Bacteria,2IBFJ@201174|Actinobacteria,4F2IF@85016|Cellulomonadaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,Pkinase
SRR25158249_k127_3957655_6	1304865.JAGF01000001_gene432	1.154e-25	109.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158249_k127_3957655_2	526225.Gobs_4221	4.634e-65	231.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria,4EV4D@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158249_k127_3957655_8	483219.LILAB_25035	4.519e-05	48.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria	1224|Proteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158249_k127_3969298_0	555088.DealDRAFT_1048	8.831e-230	732.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42JPA@68298|Syntrophomonadaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158249_k127_3969298_2	1382356.JQMP01000003_gene2419	5.136e-20	94.0	COG0789@1|root,COG0789@2|Bacteria,2G72X@200795|Chloroflexi,27YHN@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158249_k127_3969298_1	498211.CJA_1292	7.066e-33	142.0	COG2374@1|root,COG3391@1|root,COG5184@1|root,COG2374@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	mtsC	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD,Reprolysin_4,SLH,TSP_3
SRR25158249_k127_3990934_3	1268622.AVS7_01840	3.619e-14	83.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2VH62@28216|Betaproteobacteria,4AA9K@80864|Comamonadaceae	28216|Betaproteobacteria	T	osmosensitive K channel	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR25158249_k127_3990934_0	1380370.JIBA01000015_gene171	1.706e-106	353.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FIR9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_3990934_1	446466.Cfla_1494	4.152e-50	184.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158249_k127_3990934_2	1136417.AZWE01000010_gene2893	1.077e-33	145.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,2IA4H@201174|Actinobacteria,4D9U5@85008|Micromonosporales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HAMP
SRR25158249_k127_3992275_7	1380347.JNII01000007_gene178	5.643e-32	138.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158249_k127_3992275_2	1496688.ER33_12665	6.008e-121	403.0	COG0516@1|root,COG0516@2|Bacteria,1G1MX@1117|Cyanobacteria,22S1T@167375|Cyanobium	1117|Cyanobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158249_k127_3992275_1	1049564.TevJSym_ac01750	1.261e-127	414.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158249_k127_3992275_9	246200.SPO0803	1.629e-09	67.0	COG0494@1|root,COG0494@2|Bacteria,1RKVK@1224|Proteobacteria,2UE2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158249_k127_3992275_0	1123320.KB889698_gene9323	5.809e-172	572.0	COG2133@1|root,COG3055@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,GSDH,Laminin_G_3,Malectin,PKD
SRR25158249_k127_3992275_3	525904.Tter_0599	3.051e-70	250.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158249_k127_3992275_6	479434.Sthe_0949	3.338e-33	133.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YHY@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
SRR25158249_k127_3992275_8	1278073.MYSTI_03456	1.731e-24	119.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SRR25158249_k127_3992275_10	345341.KUTG_00304	5.767e-09	68.0	COG5343@1|root,COG5343@2|Bacteria,2HM9H@201174|Actinobacteria,4E3TB@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158249_k127_3992275_5	1382356.JQMP01000003_gene1500	1.742e-43	166.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27Z8H@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_3992275_4	644283.Micau_0453	1.207e-51	191.0	COG0125@1|root,COG2211@1|root,COG0125@2|Bacteria,COG2211@2|Bacteria,2GNTI@201174|Actinobacteria,4DA19@85008|Micromonosporales	201174|Actinobacteria	FG	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR25158249_k127_3998495_2	644966.Tmar_2288	4.563e-26	108.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WCGY@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158249_k127_3998495_5	1121456.ATVA01000011_gene1627	4.035e-06	51.0	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria,2MD3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158249_k127_3998495_3	632335.Calkr_1751	1.007e-25	117.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42GX3@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158249_k127_3998495_1	525904.Tter_0725	4.68e-52	193.0	COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158249_k127_3998495_4	1384065.JAGS01000001_gene2434	7.198e-21	104.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WJBH@541000|Ruminococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158249_k127_3998495_0	525904.Tter_0727	2.799e-77	270.0	COG0094@1|root,COG0094@2|Bacteria,2NP65@2323|unclassified Bacteria	2|Bacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158249_k127_400188_2	1382303.JPOM01000001_gene841	3.24e-23	113.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2KF2U@204458|Caulobacterales	204458|Caulobacterales	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158249_k127_400188_0	391625.PPSIR1_10405	1.038e-78	278.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2YWS8@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158249_k127_400188_1	1122138.AQUZ01000015_gene6845	4.574e-73	262.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4DVK7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158249_k127_4006786_0	439292.Bsel_1091	2.48e-46	183.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,26PGG@186821|Sporolactobacillaceae	91061|Bacilli	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158249_k127_4006786_3	1463825.JNXC01000071_gene3282	4.531e-05	56.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4E4IM@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158249_k127_4006786_2	42256.RradSPS_2525	1.47e-28	126.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158249_k127_4006786_1	1157637.KB892124_gene709	1.791e-29	124.0	COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria	201174|Actinobacteria	K	asnC family	lrp_3	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158249_k127_4011729_3	324602.Caur_2164	3.866e-12	77.0	COG3409@1|root,COG3409@2|Bacteria,2G8YJ@200795|Chloroflexi,377VF@32061|Chloroflexia	32061|Chloroflexia	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158249_k127_4011729_2	1380390.JIAT01000010_gene4578	7.719e-17	88.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CQFM@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
SRR25158249_k127_4011729_1	1283299.AUKG01000002_gene3791	6.591e-17	93.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158249_k127_4011729_0	1968.JOEV01000048_gene3460	4.766e-78	277.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4013957_6	235985.BBPN01000007_gene3323	8.558e-05	54.0	COG0477@1|root,COG0477@2|Bacteria,2GJ7J@201174|Actinobacteria,2NED8@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158249_k127_4013957_0	1229780.BN381_130137	6.88e-68	241.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158249_k127_4013957_3	1122622.ATWJ01000002_gene795	1.936e-32	132.0	COG1733@1|root,COG1733@2|Bacteria,2IRHS@201174|Actinobacteria,4FI6I@85021|Intrasporangiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158249_k127_4013957_4	1301100.HG529329_gene4450	1.35e-15	91.0	COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae	186801|Clostridia	F	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	kamD	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
SRR25158249_k127_4013957_2	867903.ThesuDRAFT_00783	1.595e-43	173.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158249_k127_4013957_1	1051632.TPY_1473	4.61e-60	215.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR25158249_k127_4039060_3	1380346.JNIH01000011_gene2740	3.448e-08	65.0	2BZJQ@1|root,334P7@2|Bacteria,2I8YZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158249_k127_4039060_2	1210045.ALNP01000003_gene4439	7.461e-15	89.0	COG0823@1|root,COG2304@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PD40,VWA
SRR25158249_k127_4039060_1	357808.RoseRS_0010	1.438e-58	228.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158249_k127_4039060_0	287986.DV20_29645	3.428e-76	272.0	COG1470@1|root,COG1470@2|Bacteria,2H4ZH@201174|Actinobacteria,4E24A@85010|Pseudonocardiales	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158249_k127_4039060_4	67352.JODS01000001_gene366	2.512e-07	58.0	COG2197@1|root,COG2197@2|Bacteria,2GNUE@201174|Actinobacteria	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158249_k127_404425_0	66373.JOFQ01000024_gene4657	3.731e-90	308.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158249_k127_404425_1	1501230.ET33_07475	1.277e-24	118.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,26STR@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158249_k127_404425_3	680198.SCAB_12001	1.096e-05	55.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,FixH
SRR25158249_k127_404425_2	1150599.MPHLEI_19504	6.051e-12	77.0	arCOG02771@1|root,2Z9GP@2|Bacteria,2I467@201174|Actinobacteria,232XR@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4046972_0	266117.Rxyl_2946	3.055e-70	257.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158249_k127_4054133_1	604331.AUHY01000040_gene76	1.297e-17	91.0	COG2720@1|root,COG2720@2|Bacteria,1WM1R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158249_k127_4054133_0	1245471.PCA10_30630	2.011e-118	387.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158249_k127_4061814_0	710421.Mycch_0438	7.348e-125	437.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,232BD@1762|Mycobacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_4063559_1	1128421.JAGA01000002_gene1381	1.026e-91	322.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
SRR25158249_k127_4063559_0	405948.SACE_2136	5.695e-140	452.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4E2ES@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14,1.3.5.2	ko:K00254,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158249_k127_4063559_3	356851.JOAN01000015_gene2693	1.653e-20	106.0	COG0454@1|root,COG0456@2|Bacteria,2I41B@201174|Actinobacteria,4DCVF@85008|Micromonosporales	201174|Actinobacteria	K	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_4063559_2	1449976.KALB_7718	2.296e-36	150.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4E0XA@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_4066668_0	446462.Amir_3077	1.867e-149	484.0	COG1012@1|root,COG1012@2|Bacteria,2HF1C@201174|Actinobacteria,4EA29@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158249_k127_4066668_1	1123251.ATWM01000004_gene1975	2.613e-45	168.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4FFF5@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22,4.1.1.64	ko:K00596,ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158249_k127_408443_2	635013.TherJR_2810	5.129e-35	149.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,2616F@186807|Peptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158249_k127_408443_5	1449126.JQKL01000020_gene3365	7.397e-18	98.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158249_k127_408443_3	1304275.C41B8_04471	2.953e-30	125.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158249_k127_408443_4	525904.Tter_0780	4.602e-25	106.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400	-	-	-	Ribosomal_S18
SRR25158249_k127_408443_0	794903.OPIT5_15890	1.559e-55	205.0	COG0730@1|root,COG0730@2|Bacteria,46V52@74201|Verrucomicrobia,3K9AP@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158249_k127_408443_1	264732.Moth_0818	6.481e-41	164.0	COG0530@1|root,COG0530@2|Bacteria,1UE3Y@1239|Firmicutes,25IY9@186801|Clostridia,42F30@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158249_k127_4089563_3	398578.Daci_0478	1.478e-12	73.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,2VUJS@28216|Betaproteobacteria,4AE22@80864|Comamonadaceae	28216|Betaproteobacteria	K	Cd(II) Pb(II)-responsive transcriptional regulator	cadR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158249_k127_4089563_0	1246459.KB898374_gene3976	5.862e-46	182.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158249_k127_4089563_1	1476583.DEIPH_ctg040orf0015	2.639e-33	133.0	2DNXR@1|root,32ZPP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158249_k127_4089563_2	1089547.KB913013_gene3281	5.867e-26	109.0	COG2044@1|root,COG2044@2|Bacteria,4NNYE@976|Bacteroidetes,47PVV@768503|Cytophagia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158249_k127_4094474_1	1177154.Y5S_01155	2.094e-21	104.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K20973	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
SRR25158249_k127_4094474_0	106370.Francci3_3546	2.987e-225	704.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4ERMR@85013|Frankiales	201174|Actinobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158249_k127_4094603_2	525904.Tter_0792	1.937e-64	226.0	COG0503@1|root,COG0503@2|Bacteria,2NPGX@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	PRTase_2,Pribosyltran,TRSP
SRR25158249_k127_4094603_0	298653.Franean1_1216	8.054e-92	320.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4EUMC@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_4094603_3	383372.Rcas_4176	7.662e-61	218.0	COG0500@1|root,COG2226@2|Bacteria,2GBRI@200795|Chloroflexi,3769K@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158249_k127_4094603_1	1122927.KB895419_gene2297	1.61e-77	267.0	COG0666@1|root,COG0666@2|Bacteria,1V2DE@1239|Firmicutes,4HGU4@91061|Bacilli,26WR5@186822|Paenibacillaceae	91061|Bacilli	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4
SRR25158249_k127_4094603_4	58344.JOEL01000013_gene6626	4.15e-15	76.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_4105917_1	682795.AciX8_4391	9.275e-10	64.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158249_k127_4105917_0	67352.JODS01000070_gene2256	3.79e-23	112.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158249_k127_4121466_0	880526.KE386488_gene1366	3.854e-28	119.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,2FRGC@200643|Bacteroidia	976|Bacteroidetes	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158249_k127_4121466_1	1380347.JNII01000006_gene1629	5.59e-20	101.0	COG0477@1|root,COG2814@2|Bacteria,2HF67@201174|Actinobacteria,4EWG3@85013|Frankiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158249_k127_4136762_0	1304874.JAFY01000002_gene133	7.678e-91	324.0	COG0444@1|root,COG0444@2|Bacteria,3TAUN@508458|Synergistetes	508458|Synergistetes	EP	ABC transporter	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
SRR25158249_k127_4136762_1	266835.14025830	2.201e-89	311.0	COG1173@1|root,COG1173@2|Bacteria,1NRWG@1224|Proteobacteria,2UPAF@28211|Alphaproteobacteria,43PKS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158249_k127_4136762_2	266835.14025829	4.041e-53	190.0	COG0601@1|root,COG0601@2|Bacteria,1R6RG@1224|Proteobacteria,2U10E@28211|Alphaproteobacteria,43R3C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158249_k127_4154832_0	1211114.ALIP01000113_gene866	7.174e-150	487.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1X3MQ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158249_k127_4164624_1	357808.RoseRS_3827	1.448e-106	347.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi,3767V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K15052	ko00720,ko01200,map00720,map01200	M00376	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158249_k127_4164624_0	1045855.DSC_02185	1.064e-142	462.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1X2ZC@135614|Xanthomonadales	135614|Xanthomonadales	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158249_k127_4166495_1	1122223.KB890696_gene92	2.874e-44	181.0	COG0494@1|root,COG0494@2|Bacteria,1WIME@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158249_k127_4166495_2	867903.ThesuDRAFT_02179	1.121e-28	128.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WDJP@538999|Clostridiales incertae sedis	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
SRR25158249_k127_4166495_0	349124.Hhal_1500	4.182e-122	419.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X0IX@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158249_k127_4166495_3	1408424.JHYI01000023_gene4243	1.013e-11	76.0	COG5061@1|root,COG5061@2|Bacteria,1VF12@1239|Firmicutes,4HQ46@91061|Bacilli,1ZD53@1386|Bacillus	91061|Bacilli	OU	Protein of unknown function (DUF3307)	satE	-	-	-	-	-	-	-	-	-	-	-	DUF3307
SRR25158249_k127_4166495_4	1227261.HMPREF0043_01134	3.788e-08	63.0	COG2522@1|root,COG2522@2|Bacteria,2IP64@201174|Actinobacteria,4D6D2@85005|Actinomycetales	201174|Actinobacteria	O	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	SatD
SRR25158249_k127_4168509_4	429009.Adeg_1035	0.0004035	45.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,24UMJ@186801|Clostridia,42HJV@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158249_k127_4168509_2	1521187.JPIM01000065_gene1267	7.707e-31	137.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi,3752U@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158249_k127_4168509_0	479434.Sthe_1615	1.796e-74	258.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158249_k127_4168509_1	867903.ThesuDRAFT_00030	1.64e-37	163.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,3WDR4@538999|Clostridiales incertae sedis	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158249_k127_4168509_3	765420.OSCT_2587	8.218e-06	58.0	COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia	32061|Chloroflexia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4169751_2	1449049.JONW01000005_gene1431	4.285e-10	65.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,2KFF7@204458|Caulobacterales	204458|Caulobacterales	L	A G-specific adenine glycosylase	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX_4
SRR25158249_k127_4169751_1	444157.Tneu_1126	1.757e-28	125.0	COG0063@1|root,arCOG00018@2157|Archaea,2XPXN@28889|Crenarchaeota	28889|Crenarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158249_k127_4169751_0	1068978.AMETH_3739	8.658e-127	425.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4DYGV@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158249_k127_4169751_3	1336245.JAGO01000017_gene1119	2.979e-07	63.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XHG3@135619|Oceanospirillales	135619|Oceanospirillales	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_4174531_2	1150864.MILUP08_43948	1.553e-46	189.0	COG2072@1|root,COG2072@2|Bacteria,2GNGX@201174|Actinobacteria,4DAXR@85008|Micromonosporales	201174|Actinobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
SRR25158249_k127_4174531_4	1166018.FAES_4235	3.822e-14	78.0	COG1413@1|root,COG2905@1|root,COG1413@2|Bacteria,COG2905@2|Bacteria,4PKPI@976|Bacteroidetes,47YF3@768503|Cytophagia	976|Bacteroidetes	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
SRR25158249_k127_4174531_3	926569.ANT_10990	1.765e-23	105.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158249_k127_4174531_0	1380347.JNII01000006_gene1592	1.227e-134	462.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158249_k127_4174531_1	1396418.BATQ01000184_gene2632	9.136e-127	442.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158249_k127_4174531_5	485913.Krac_3704	1.426e-10	68.0	COG0477@1|root,COG2814@2|Bacteria,2G77Q@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_4179972_7	357808.RoseRS_3953	1.492e-11	74.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,SLH
SRR25158249_k127_4179972_2	1382306.JNIM01000001_gene1527	6.002e-91	321.0	COG0642@1|root,COG2205@2|Bacteria,2G601@200795|Chloroflexi	200795|Chloroflexi	T	Osmosensitive K+ channel His kinase sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	KdpD,Usp
SRR25158249_k127_4179972_3	1123257.AUFV01000003_gene1035	1.08e-55	201.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,1S2B0@1236|Gammaproteobacteria,1X6DA@135614|Xanthomonadales	135614|Xanthomonadales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRR25158249_k127_4179972_0	1382356.JQMP01000003_gene1965	3.435e-255	806.0	COG2216@1|root,COG2216@2|Bacteria,2G64Q@200795|Chloroflexi	200795|Chloroflexi	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
SRR25158249_k127_4179972_1	595536.ADVE02000001_gene2591	5.311e-199	634.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,2TSIJ@28211|Alphaproteobacteria,36X2M@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Potassium-transporting ATPase A subunit	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158249_k127_4179972_5	1382356.JQMP01000003_gene1961	4.694e-16	87.0	COG0745@1|root,COG0745@2|Bacteria,2G9SH@200795|Chloroflexi	200795|Chloroflexi	T	SPTR D1CGX5 Response regulator receiver protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158249_k127_4179972_4	595536.ADVE02000001_gene3365	6.172e-54	201.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,36Y5H@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_4179972_6	349521.HCH_00065	1.245e-11	66.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,1T1PS@1236|Gammaproteobacteria,1XIBR@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158249_k127_4190010_0	929556.Solca_0050	2.218e-30	135.0	COG1470@1|root,COG3209@1|root,COG4932@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia	976|Bacteroidetes	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
SRR25158249_k127_4190010_1	864051.BurJ1DRAFT_3700	1.222e-08	67.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
SRR25158249_k127_4192653_3	401526.TcarDRAFT_1987	9.353e-16	91.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes	909932|Negativicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
SRR25158249_k127_4192653_1	404589.Anae109_2816	2.326e-50	191.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158249_k127_4192653_2	1278078.G419_02540	2.593e-45	168.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4G18A@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158249_k127_4192653_0	479432.Sros_9278	4.769e-81	275.0	COG0600@1|root,COG0600@2|Bacteria,2GIWG@201174|Actinobacteria,4EI0V@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	ssuC3	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158249_k127_4202476_10	1470593.BW43_04591	2.025e-19	90.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033744,GO:0036456,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114,GO:0071704,GO:1901564	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	iECSE_1348.ECSE_4525	PMSR
SRR25158249_k127_4202476_8	525904.Tter_2860	5.723e-61	214.0	COG0346@1|root,COG0346@2|Bacteria,2NR21@2323|unclassified Bacteria	2|Bacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4,IU_nuc_hydro
SRR25158249_k127_4202476_1	1122138.AQUZ01000008_gene3768	1.188e-115	373.0	2A0U6@1|root,30NYZ@2|Bacteria,2H2K1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YecM
SRR25158249_k127_4202476_5	1122132.AQYH01000016_gene2877	1.581e-86	295.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,4B7K7@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Nucleoside	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158249_k127_4202476_0	1121377.KB906400_gene1321	1.164e-142	467.0	COG2723@1|root,COG2723@2|Bacteria,1WIBW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glycosyl hydrolase family 1	-	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
SRR25158249_k127_4202476_2	324602.Caur_1110	4.586e-110	379.0	COG1472@1|root,COG1472@2|Bacteria,2G8JU@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158249_k127_4202476_3	316274.Haur_1178	4.125e-101	350.0	COG0395@1|root,COG0395@2|Bacteria,2G82A@200795|Chloroflexi,375TC@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158249_k127_4202476_6	91464.S7335_2794	2.249e-81	291.0	COG1175@1|root,COG1175@2|Bacteria,1G3BG@1117|Cyanobacteria,1H03Q@1129|Synechococcus	1117|Cyanobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158249_k127_4202476_4	316274.Haur_1180	5.256e-98	340.0	COG1653@1|root,COG1653@2|Bacteria,2G8AR@200795|Chloroflexi,376NE@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158249_k127_4202476_9	926550.CLDAP_35960	1.212e-48	194.0	COG1940@1|root,COG1940@2|Bacteria,2G6H1@200795|Chloroflexi	200795|Chloroflexi	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158249_k127_4202476_7	316274.Haur_1182	1.372e-78	274.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi,375G6@32061|Chloroflexia	32061|Chloroflexia	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
SRR25158249_k127_4219245_4	292459.STH1897	5.622e-27	120.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Put_Phosphatase
SRR25158249_k127_4219245_5	105422.BBPM01000059_gene722	1.528e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,2NHED@228398|Streptacidiphilus	201174|Actinobacteria	K	ECF sigma factor	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_4219245_10	246197.MXAN_5756	2.811e-11	76.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158249_k127_4219245_1	313589.JNB_13288	1.686e-82	287.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	LysM,PD40
SRR25158249_k127_4219245_3	479434.Sthe_0069	6.723e-68	237.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Nitroreductase
SRR25158249_k127_4219245_7	562970.Btus_2417	8.089e-21	99.0	COG1595@1|root,COG1595@2|Bacteria,1VFMV@1239|Firmicutes,4HPMS@91061|Bacilli,27A8M@186823|Alicyclobacillaceae	91061|Bacilli	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_4219245_6	379066.GAU_0527	9.598e-22	102.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_4219245_2	313589.JNB_13288	4.173e-77	276.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	LysM,PD40
SRR25158249_k127_4219245_9	1283299.AUKG01000001_gene2156	5.159e-15	83.0	COG1595@1|root,COG1595@2|Bacteria,2HQ92@201174|Actinobacteria,4CRT0@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_4219245_11	953739.SVEN_7420	1.692e-06	60.0	COG3055@1|root,COG3055@2|Bacteria,2I91M@201174|Actinobacteria	201174|Actinobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
SRR25158249_k127_4219245_0	1128421.JAGA01000002_gene468	8.44e-246	770.0	COG0504@1|root,COG0504@2|Bacteria,2NNVG@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377	CTP_synth_N,GATase
SRR25158249_k127_4223099_3	266117.Rxyl_0792	2.311e-13	83.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria	201174|Actinobacteria	V	Methicillin resistance protein	femX	-	2.3.2.10	ko:K05363,ko:K18354	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	R08779	RC00055,RC00096	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	FemAB
SRR25158249_k127_4223099_1	1232436.CAPF01000004_gene233	1.137e-38	168.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CVFS@84998|Coriobacteriia	84998|Coriobacteriia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRR25158249_k127_4223099_0	1382356.JQMP01000003_gene2578	1.644e-69	258.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158249_k127_4223099_2	264732.Moth_1028	5.141e-28	114.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42HMW@68295|Thermoanaerobacterales	186801|Clostridia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158249_k127_4237722_1	1288826.MSNKSG1_05471	2.707e-68	234.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,465MD@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG1070 Sugar (pentulose and hexulose) kinases	ygcE	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_4237722_0	1386089.N865_05445	6.163e-103	342.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4FF6H@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158249_k127_4242362_1	485913.Krac_4116	1.157e-123	418.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi	2|Bacteria	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158249_k127_4242362_2	1120950.KB892796_gene2259	2.171e-32	142.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158249_k127_4242362_0	397278.JOJN01000008_gene2467	1.562e-167	544.0	COG0154@1|root,COG0154@2|Bacteria,2GSDB@201174|Actinobacteria,4DPCU@85009|Propionibacteriales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158249_k127_4242362_3	477641.MODMU_0504	1.307e-27	114.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4EUCM@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4245990_0	309801.trd_1240	1.329e-191	611.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,27XYD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158249_k127_4250210_0	368407.Memar_0638	9.238e-57	210.0	COG0648@1|root,arCOG01894@2157|Archaea,2XV5I@28890|Euryarchaeota	28890|Euryarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158249_k127_4250210_3	1380393.JHVP01000002_gene1562	2.185e-21	103.0	COG3860@1|root,COG3860@2|Bacteria,2IQEK@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20
SRR25158249_k127_4250210_2	574087.Acear_0275	8.887e-35	140.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3WAMR@53433|Halanaerobiales	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158249_k127_425155_1	561175.KB894103_gene1290	2.858e-59	218.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158249_k127_425155_0	1206101.AZXC01000001_gene4379	2.185e-95	337.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
SRR25158249_k127_4253577_5	1118060.CAGZ01000015_gene1780	6.02e-09	57.0	COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4CW9M@84998|Coriobacteriia	84998|Coriobacteriia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158249_k127_4253577_4	1444309.JAQG01000004_gene3592	4.189e-23	106.0	COG2318@1|root,COG2318@2|Bacteria,1VW3T@1239|Firmicutes,4HWQI@91061|Bacilli,26Y17@186822|Paenibacillaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158249_k127_4253577_0	1401064.HMPREF2129_07175	8.539e-104	356.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,22JU8@1653|Corynebacteriaceae	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158249_k127_4253577_1	1380763.BG53_00385	2.702e-92	319.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,26UYF@186822|Paenibacillaceae	91061|Bacilli	S	Transporter associated domain	hlyX	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158249_k127_4253577_2	1041930.Mtc_0877	1.281e-76	270.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2N97R@224756|Methanomicrobia	224756|Methanomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158249_k127_4253577_3	479434.Sthe_0953	2.064e-36	146.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,27YAT@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158249_k127_4258230_1	765420.OSCT_1250	2.194e-27	121.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi,375QN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158249_k127_4258230_0	649831.L083_3685	2.853e-82	281.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4D9B7@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS,PAS_4
SRR25158249_k127_4265591_1	469383.Cwoe_3714	8.061e-42	157.0	COG1487@1|root,COG1487@2|Bacteria,2IGMY@201174|Actinobacteria,4CT46@84995|Rubrobacteria	84995|Rubrobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158249_k127_4265591_0	237368.SCABRO_01228	8.493e-100	338.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1b
SRR25158249_k127_4265591_2	1380390.JIAT01000009_gene2228	8.475e-30	126.0	COG2258@1|root,COG2258@2|Bacteria,2GRBQ@201174|Actinobacteria,4CQID@84995|Rubrobacteria	84995|Rubrobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158249_k127_4273158_2	101510.RHA1_ro05363	1.544e-16	81.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4G39U@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR25158249_k127_4273158_1	1121924.ATWH01000010_gene946	4.347e-55	198.0	COG1670@1|root,COG1670@2|Bacteria,2IFM4@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_4273158_0	1040989.AWZU01000125_gene3972	3.409e-249	777.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3JTRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158249_k127_4273158_3	684949.ATTJ01000002_gene299	2.283e-05	49.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158249_k127_4282800_1	446470.Snas_5055	3.189e-90	308.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4F0CB@85014|Glycomycetales	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158249_k127_4282800_0	1463854.JOHT01000015_gene5347	5.271e-108	360.0	COG0667@1|root,COG0667@2|Bacteria,2GKW7@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SRR25158249_k127_4282800_2	1123322.KB904658_gene1265	3.673e-88	323.0	COG3618@1|root,COG3618@2|Bacteria,2GM2D@201174|Actinobacteria	201174|Actinobacteria	C	amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158249_k127_4282800_4	1449976.KALB_4150	1.612e-15	84.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria,4E4YD@85010|Pseudonocardiales	201174|Actinobacteria	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158249_k127_4282800_3	344747.PM8797T_02814	1.459e-30	132.0	COG0479@1|root,COG0479@2|Bacteria,2IWTB@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRR25158249_k127_4294984_1	1380393.JHVP01000009_gene1343	2.565e-73	252.0	COG1506@1|root,COG1506@2|Bacteria,2GNG5@201174|Actinobacteria,4ES4B@85013|Frankiales	201174|Actinobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158249_k127_4294984_0	526225.Gobs_1542	1.728e-90	306.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4ERDH@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158249_k127_4307727_4	272558.10175099	1.135e-24	105.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158249_k127_4307727_3	1385510.N781_12315	3.561e-39	149.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,2YAG5@289201|Pontibacillus	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158249_k127_4307727_0	2002.JOEQ01000008_gene1129	1.475e-117	397.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4EIXN@85012|Streptosporangiales	201174|Actinobacteria	S	Phenazine biosynthesis-like protein	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158249_k127_4307727_2	395961.Cyan7425_1166	2.247e-58	221.0	COG0164@1|root,COG0164@2|Bacteria,1G507@1117|Cyanobacteria,3KHNX@43988|Cyanothece	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158249_k127_4307727_5	448385.sce2912	4.335e-11	68.0	COG0792@1|root,COG0792@2|Bacteria,1Q8YJ@1224|Proteobacteria,43AAG@68525|delta/epsilon subdivisions,2X233@28221|Deltaproteobacteria,2Z2KT@29|Myxococcales	28221|Deltaproteobacteria	J	nuclease activity	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158249_k127_4307727_1	525904.Tter_1520	3.196e-89	306.0	COG0052@1|root,COG0052@2|Bacteria,2NP4M@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158249_k127_4307727_6	1125863.JAFN01000001_gene969	0.0002896	45.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158249_k127_4350765_4	1120797.KB908273_gene2293	5.819e-39	149.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,234CE@1762|Mycobacteriaceae	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158249_k127_4350765_0	1121918.ARWE01000001_gene385	9.931e-162	525.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158249_k127_4350765_2	1463855.JOHV01000020_gene3024	1.271e-51	196.0	COG0600@1|root,COG0600@2|Bacteria,2HDX7@201174|Actinobacteria	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158249_k127_4350765_1	649638.Trad_0922	2.139e-91	323.0	COG1116@1|root,COG1116@2|Bacteria,1WM71@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158249_k127_4350765_3	1122175.ATXU01000011_gene1641	6.442e-46	187.0	COG0600@1|root,COG0600@2|Bacteria,2IFIB@201174|Actinobacteria,4FNJP@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158249_k127_4353704_1	1384054.N790_07795	2.66e-66	242.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1X42C@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158249_k127_4353704_2	1174684.EBMC1_13181	1.202e-41	161.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,2K3VV@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158249_k127_4353704_4	557598.LHK_01840	0.0003895	51.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KPE8@206351|Neisseriales	206351|Neisseriales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158249_k127_4353704_0	1379270.AUXF01000003_gene3787	2.569e-69	247.0	COG0008@1|root,COG0008@2|Bacteria,1ZURR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
SRR25158249_k127_4353704_3	146922.JOFU01000005_gene7084	3.9e-11	66.0	2A543@1|root,30TSR@2|Bacteria,2I8HY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_435877_1	867903.ThesuDRAFT_00368	2.184e-31	127.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,3WCEP@538999|Clostridiales incertae sedis	186801|Clostridia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158249_k127_435877_0	264732.Moth_0719	4.25e-56	203.0	COG0586@1|root,COG0586@2|Bacteria,1V62W@1239|Firmicutes,25B64@186801|Clostridia	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158249_k127_435877_2	765910.MARPU_08415	6.469e-22	102.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1SAR4@1236|Gammaproteobacteria,1X0DQ@135613|Chromatiales	135613|Chromatiales	G	Phosphoglycerate mutase family	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158249_k127_4365575_3	357808.RoseRS_0293	1.166e-29	134.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158249_k127_4365575_0	1254432.SCE1572_08545	2.273e-46	189.0	COG1247@1|root,COG1247@2|Bacteria,1RGU8@1224|Proteobacteria,43B5R@68525|delta/epsilon subdivisions,2X6JB@28221|Deltaproteobacteria,2YVMN@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158249_k127_4365575_2	1382306.JNIM01000001_gene2482	1.111e-33	148.0	COG3662@1|root,COG3662@2|Bacteria,2G8VS@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158249_k127_4365575_1	1906.SFRA_07595	3.901e-46	177.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria	201174|Actinobacteria	S	BioY protein	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158249_k127_4365575_4	1394178.AWOO02000080_gene2095	2.615e-28	131.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158249_k127_4369656_9	1120934.KB894448_gene3042	5.032e-18	87.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4DX8Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158249_k127_4369656_5	351607.Acel_0571	1.111e-51	203.0	COG1028@1|root,COG1028@2|Bacteria,2GQBK@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158249_k127_4369656_6	29306.JOBE01000022_gene527	8.204e-26	124.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria	201174|Actinobacteria	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158249_k127_4369656_2	1380390.JIAT01000010_gene4692	2.138e-136	464.0	COG1053@1|root,COG1053@2|Bacteria,2HD4N@201174|Actinobacteria	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
SRR25158249_k127_4369656_3	1968.JOEV01000003_gene3298	3.43e-81	300.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
SRR25158249_k127_4369656_7	477641.MODMU_2470	1.028e-23	107.0	COG1113@1|root,COG1113@2|Bacteria,2GRKY@201174|Actinobacteria,4EWX2@85013|Frankiales	201174|Actinobacteria	E	amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4369656_0	189425.PGRAT_30985	6.095e-314	994.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,26TAI@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	2.4.1.64,5.4.2.6	ko:K01838,ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SRR25158249_k127_4369656_1	330214.NIDE1067	1.698e-193	628.0	2DBJW@1|root,2Z9P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4369656_8	929712.KI912613_gene4710	1.346e-19	100.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158249_k127_4369656_4	292564.Cyagr_0723	4.519e-69	241.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria,22SBE@167375|Cyanobium	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158249_k127_4379087_1	264731.PRU_0891	1.004e-11	75.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,2FN9H@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158249_k127_4379087_0	867903.ThesuDRAFT_02331	2.823e-116	389.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WCZC@538999|Clostridiales incertae sedis	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158249_k127_4379087_2	292459.STH193	0.0001077	50.0	COG4856@1|root,COG4856@2|Bacteria	2|Bacteria	O	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158249_k127_4381672_2	1869.MB27_42030	1.166e-10	72.0	2DPD0@1|root,331J4@2|Bacteria,2IFZU@201174|Actinobacteria,4DCU1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4381672_0	1382306.JNIM01000001_gene3725	5.734e-33	134.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi	200795|Chloroflexi	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158249_k127_4381672_3	1131812.JQMS01000001_gene1392	2.801e-09	62.0	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1I534@117743|Flavobacteriia,2NXJZ@237|Flavobacterium	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158249_k127_4381672_1	1279017.AQYJ01000028_gene2297	2.692e-18	94.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AB4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG2909 ATP-dependent transcriptional regulator	malT	GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158249_k127_4382523_0	485913.Krac_12535	4.694e-272	848.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158249_k127_4394304_0	765420.OSCT_1250	4.134e-28	123.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi,375QN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158249_k127_4394304_1	1400520.LFAB_03235	3.966e-19	100.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae	91061|Bacilli	EGP	transporter	blt	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1
SRR25158249_k127_4397045_0	1120950.KB892813_gene7108	6.27e-72	263.0	2F3NN@1|root,33WFN@2|Bacteria,2IPYP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4397045_2	383372.Rcas_2388	3.98e-49	197.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi,374SS@32061|Chloroflexia	32061|Chloroflexia	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158249_k127_4397045_1	926569.ANT_07490	8.069e-59	216.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158249_k127_4397045_3	1122175.ATXU01000011_gene1626	1.544e-16	81.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FMND@85023|Microbacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158249_k127_4429784_3	351607.Acel_0576	3.95e-65	230.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria	201174|Actinobacteria	S	protein containing SIS (Sugar isomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158249_k127_4429784_1	1150399.AQYK01000001_gene896	3.16e-111	374.0	COG0673@1|root,COG0673@2|Bacteria,2IH5W@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158249_k127_4429784_2	926560.KE387023_gene1711	1.321e-86	292.0	COG0274@1|root,COG0274@2|Bacteria,1WMRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	DeoC/LacD family aldolase	-	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158249_k127_4429784_0	1297569.MESS2_1340012	6.081e-149	481.0	COG1082@1|root,COG1082@2|Bacteria,1PKSR@1224|Proteobacteria,2U1RX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158249_k127_4429784_4	351607.Acel_0581	3.478e-19	89.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4EVFT@85013|Frankiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158249_k127_4441235_0	1380347.JNII01000005_gene2789	3.468e-68	244.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158249_k127_4441235_1	448385.sce0251	4.725e-63	228.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2YWS8@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158249_k127_4445898_1	935948.KE386494_gene461	9.222e-99	344.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,42FU6@68295|Thermoanaerobacterales	186801|Clostridia	F	Amidohydrolase family	hydA	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1,Urease_alpha
SRR25158249_k127_4445898_2	479434.Sthe_2907	1.626e-39	154.0	COG2164@1|root,COG2164@2|Bacteria,2G8JQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
SRR25158249_k127_4445898_8	298654.FraEuI1c_5884	6.792e-17	84.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4ET7Y@85013|Frankiales	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158249_k127_4445898_9	78898.MVEG_10759T0	1.612e-16	87.0	2CI4P@1|root,2S48Z@2759|Eukaryota,3A1KV@33154|Opisthokonta,3Q1A9@4751|Fungi,1GUKU@112252|Fungi incertae sedis	4751|Fungi	S	OHCU decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox
SRR25158249_k127_4445898_7	515635.Dtur_0211	2.809e-20	104.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019,ko:K13292	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158249_k127_4445898_3	1395513.P343_14660	3.692e-39	153.0	COG1279@1|root,COG1279@2|Bacteria,1UII1@1239|Firmicutes,4ISII@91061|Bacilli	91061|Bacilli	S	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158249_k127_4445898_4	926550.CLDAP_04280	1.294e-28	130.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158249_k127_4445898_5	1035308.AQYY01000002_gene342	2.13e-24	117.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158249_k127_4445898_6	926550.CLDAP_04260	5.622e-22	100.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158249_k127_4445898_10	383372.Rcas_1424	1.981e-11	72.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,375ZH@32061|Chloroflexia	32061|Chloroflexia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158249_k127_4445898_11	742723.HMPREF9477_01585	9.068e-10	67.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,27QHB@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158249_k127_4445898_0	525904.Tter_0001	1.343e-134	441.0	COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158249_k127_4467696_1	936573.HMPREF1147_2010	2.235e-69	259.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4H27E@909932|Negativicutes	909932|Negativicutes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158249_k127_4467696_0	1128421.JAGA01000002_gene200	1.412e-108	375.0	COG1461@1|root,COG1461@2|Bacteria,2NPHY@2323|unclassified Bacteria	2|Bacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158249_k127_4467696_3	867903.ThesuDRAFT_00324	0.0009234	48.0	COG1302@1|root,COG1302@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158249_k127_4467696_2	1380367.JIBC01000003_gene3903	1.066e-19	89.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2U79I@28211|Alphaproteobacteria,3ZXHY@60136|Sulfitobacter	28211|Alphaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158249_k127_4472311_2	1121380.JNIW01000033_gene3728	2.421e-20	93.0	COG0626@1|root,COG0626@2|Bacteria,1WJNP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Cys Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158249_k127_4472311_3	926554.KI912654_gene4457	7.366e-09	68.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.218	ko:K10710	-	-	R08124	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
SRR25158249_k127_4472311_0	1173025.GEI7407_3639	8.813e-128	426.0	COG0064@1|root,COG0064@2|Bacteria,1G0H0@1117|Cyanobacteria,1H7I7@1150|Oscillatoriales	1117|Cyanobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158249_k127_4473036_1	398511.BpOF4_11115	4.912e-07	59.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158249_k127_4473036_0	326427.Cagg_0517	1.015e-09	62.0	COG0789@1|root,COG0789@2|Bacteria,2GBIN@200795|Chloroflexi,375XH@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158249_k127_4505868_0	926560.KE387023_gene1701	3.003e-108	360.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158249_k127_4505868_2	926560.KE387023_gene1701	4.529e-13	75.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158249_k127_4505868_1	981384.AEYW01000001_gene1564	2.361e-43	166.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1PYP4@1224|Proteobacteria,2TVEP@28211|Alphaproteobacteria,4NCYJ@97050|Ruegeria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
SRR25158249_k127_4506080_1	1304865.JAGF01000001_gene3605	3.215e-16	91.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4F0K7@85016|Cellulomonadaceae	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158249_k127_4506080_2	1297742.A176_00544	1.531e-06	59.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,4320V@68525|delta/epsilon subdivisions,2WW8U@28221|Deltaproteobacteria,2YW2I@29|Myxococcales	28221|Deltaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C
SRR25158249_k127_4506080_0	1206730.BAGA01000034_gene3735	2.078e-92	330.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4FU2Y@85025|Nocardiaceae	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158249_k127_4513862_1	383372.Rcas_2041	4.561e-27	118.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,377DW@32061|Chloroflexia	32061|Chloroflexia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158249_k127_4513862_0	760568.Desku_3352	1.239e-113	374.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,2618F@186807|Peptococcaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_4539740_0	82654.Pse7367_0992	8.022e-30	128.0	COG4106@1|root,COG4106@2|Bacteria,1GQ61@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158249_k127_4539740_1	1242864.D187_008094	4.561e-18	87.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria,2YUYZ@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158249_k127_4554293_0	1265310.CCBD010000050_gene1996	2.609e-83	308.0	COG2114@1|root,COG2197@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRR25158249_k127_4554293_1	65093.PCC7418_3466	2.196e-13	71.0	COG4118@1|root,COG4118@2|Bacteria,1G8Z1@1117|Cyanobacteria	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158249_k127_4574069_1	321327.CYA_1925	3.46e-126	434.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1GYDR@1129|Synechococcus	1117|Cyanobacteria	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158249_k127_4574069_0	926569.ANT_16170	1.387e-175	559.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158249_k127_4574069_3	68260.JOAY01000024_gene1073	4.676e-23	114.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158249_k127_4574069_2	670487.Ocepr_2189	2.794e-37	156.0	COG0182@1|root,COG0182@2|Bacteria,1WI3U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158249_k127_458552_1	298655.KI912266_gene30	1.438e-138	447.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158249_k127_458552_2	485913.Krac_11396	8.267e-108	361.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_458552_0	1229780.BN381_110006	2.541e-228	720.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_458552_3	1907.SGLAU_27095	1.181e-70	243.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria	201174|Actinobacteria	F	Dihydropyrimidinase	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158249_k127_4589880_2	547559.Nmag_0507	4.381e-66	236.0	COG2820@1|root,arCOG01324@2157|Archaea,2XSWN@28890|Euryarchaeota,23SKE@183963|Halobacteria	183963|Halobacteria	F	Uridine phosphorylase	udp2	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158249_k127_4589880_3	1459636.NTE_03059	3.887e-14	72.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4589880_0	1382306.JNIM01000001_gene4155	1.015e-152	496.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158249_k127_4589880_1	370438.PTH_2722	2.786e-143	465.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158249_k127_4619253_2	864702.OsccyDRAFT_1314	8.576e-70	240.0	COG4122@1|root,COG4122@2|Bacteria,1G2Y6@1117|Cyanobacteria,1H74J@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158249_k127_4619253_1	326427.Cagg_1100	2.726e-75	261.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158249_k127_4619253_0	429009.Adeg_0526	4.592e-129	429.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158249_k127_4619253_3	521098.Aaci_2086	4.389e-32	140.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HG88@91061|Bacilli	91061|Bacilli	K	domain protein	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158249_k127_4622668_1	446470.Snas_5106	1.899e-37	156.0	COG3173@1|root,COG3173@2|Bacteria,2I4EA@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158249_k127_4622668_0	1121019.AUMN01000004_gene1517	3.29e-59	213.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,1WB4T@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158249_k127_4623293_0	309801.trd_0212	1.249e-284	902.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,27XRT@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158249_k127_4632614_0	675635.Psed_0414	4.394e-79	279.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158249_k127_4632614_1	987059.RBXJA2T_01620	4.22e-33	136.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,1KKCR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158249_k127_4647656_1	1206744.BAGL01000013_gene6045	1.967e-28	121.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158249_k127_4647656_0	1320556.AVBP01000012_gene3572	1.853e-119	400.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
SRR25158249_k127_4647656_2	35754.JNYJ01000020_gene289	8.145e-14	72.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158249_k127_4652147_2	1120954.ATXE01000001_gene1926	6.298e-16	81.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2I8T8@201174|Actinobacteria,4DS8V@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158249_k127_4652147_1	313589.JNB_13118	7.089e-69	249.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4FFUC@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158249_k127_4652147_3	1125971.ASJB01000028_gene7905	8.687e-15	81.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4E0YC@85010|Pseudonocardiales	201174|Actinobacteria	E	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158249_k127_4652147_0	465541.ATCJ01000005_gene6770	4.657e-107	361.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria	201174|Actinobacteria	S	amine oxidase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,DUF1365
SRR25158249_k127_4652147_4	588932.JHOF01000018_gene1381	5.78e-07	56.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2KGJK@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
SRR25158249_k127_466245_1	446469.Sked_04810	1.83e-51	202.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158249_k127_466245_0	766499.C357_13977	9.701e-205	650.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158249_k127_4670991_1	1463825.JNXC01000002_gene4506	1.135e-08	68.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DX8K@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,TPR_12
SRR25158249_k127_4670991_0	479434.Sthe_2024	4.797e-24	105.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158249_k127_4674902_3	243231.GSU1970	4.289e-27	111.0	COG2089@1|root,COG2089@2|Bacteria,1N3PZ@1224|Proteobacteria,43A02@68525|delta/epsilon subdivisions,2X267@28221|Deltaproteobacteria,43V56@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NeuB family	neuB	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
SRR25158249_k127_4674902_0	243231.GSU1969	1.391e-230	721.0	28II9@1|root,2Z8JC@2|Bacteria,1NSFW@1224|Proteobacteria,42PTJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4674902_2	243231.GSU1968	6.107e-136	462.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,43TN9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158249_k127_4674902_1	243231.GSU1966	8.209e-196	621.0	COG4310@1|root,COG4310@2|Bacteria,1NDWT@1224|Proteobacteria,42PN9@68525|delta/epsilon subdivisions,2WPQV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47,Peptidase_M28
SRR25158249_k127_4700081_3	1382356.JQMP01000003_gene2395	1.631e-85	297.0	COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi,27YRR@189775|Thermomicrobia	189775|Thermomicrobia	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158249_k127_4700081_0	1463917.JODC01000032_gene9050	3.283e-199	629.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158249_k127_4700081_2	926550.CLDAP_34330	2.44e-118	396.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
SRR25158249_k127_4700081_1	926550.CLDAP_34320	4.387e-187	602.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158249_k127_4700081_4	1380390.JIAT01000010_gene3321	4.916e-67	238.0	COG1414@1|root,COG1414@2|Bacteria,2HGKG@201174|Actinobacteria,4CTN3@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158249_k127_4705022_1	298655.KI912267_gene7267	1.68e-13	71.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158249_k127_4705022_2	1453503.AU05_04935	4.681e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,1N1F5@1224|Proteobacteria,1SAR2@1236|Gammaproteobacteria,1YJTW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	ECF sigma factor	hasI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_4705022_0	570268.ANBB01000050_gene4000	1.14e-44	185.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria,4EG63@85012|Streptosporangiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_4724521_0	1298863.AUEP01000009_gene171	1.728e-119	391.0	2DB71@1|root,2Z7JE@2|Bacteria,2I2SN@201174|Actinobacteria	201174|Actinobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158249_k127_4724521_1	1283287.KB822583_gene2850	1.791e-79	275.0	COG3025@1|root,COG3025@2|Bacteria,2IN8R@201174|Actinobacteria	201174|Actinobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
SRR25158249_k127_4724521_2	1245471.PCA10_30630	4.718e-60	210.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158249_k127_4725250_4	1125971.ASJB01000057_gene5222	5.914e-15	78.0	COG1277@1|root,COG1277@2|Bacteria,2IING@201174|Actinobacteria,4E5D6@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
SRR25158249_k127_4725250_1	479434.Sthe_3439	1.085e-56	212.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	200795|Chloroflexi	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158249_k127_4725250_2	1385935.N836_14195	7.131e-49	190.0	COG0697@1|root,COG0697@2|Bacteria,1G44U@1117|Cyanobacteria,1HEQG@1150|Oscillatoriales	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158249_k127_4725250_0	526225.Gobs_3779	1.521e-68	244.0	COG0329@1|root,COG0329@2|Bacteria,2IBEF@201174|Actinobacteria	201174|Actinobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158249_k127_4725250_5	258533.BN977_00605	3.285e-06	60.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,234US@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA_3
SRR25158249_k127_4725250_3	455632.SGR_1294	1.543e-29	125.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,417QA@629295|Streptomyces griseus group	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	hrrA2	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158249_k127_4758454_3	1307759.JOMJ01000004_gene2508	6.636e-17	87.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,42XKF@68525|delta/epsilon subdivisions,2WT6J@28221|Deltaproteobacteria,2M8UX@213115|Desulfovibrionales	28221|Deltaproteobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158249_k127_4758454_1	323850.Shew_1642	1.936e-34	152.0	COG1361@1|root,COG1361@2|Bacteria,1R6R8@1224|Proteobacteria,1RZFS@1236|Gammaproteobacteria,2Q9ZJ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
SRR25158249_k127_4758454_2	1274374.CBLK010000009_gene4394	2.093e-18	100.0	COG3397@1|root,COG3469@1|root,COG3397@2|Bacteria,COG3469@2|Bacteria,1TT45@1239|Firmicutes,4HEJN@91061|Bacilli,26TIE@186822|Paenibacillaceae	91061|Bacilli	G	PFAM chitin-binding domain 3 protein	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10,fn3
SRR25158249_k127_4758454_4	864051.BurJ1DRAFT_0446	0.0002307	51.0	COG1476@1|root,COG1476@2|Bacteria,1NPDH@1224|Proteobacteria,2VX05@28216|Betaproteobacteria	28216|Betaproteobacteria	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158249_k127_4758454_0	1286631.X805_11440	2.591e-39	149.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1KJDB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158249_k127_4761865_0	653386.HMPREF0975_02362	2.414e-153	501.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4D3J5@85005|Actinomycetales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158249_k127_4762939_1	1254432.SCE1572_09945	2.68e-82	291.0	COG5555@1|root,COG5555@2|Bacteria,1QX82@1224|Proteobacteria,43CYG@68525|delta/epsilon subdivisions,2X86M@28221|Deltaproteobacteria,2Z3M6@29|Myxococcales	28221|Deltaproteobacteria	N	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
SRR25158249_k127_4762939_0	926569.ANT_02010	1.079e-83	288.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158249_k127_4762939_2	43354.JOIJ01000011_gene2685	1.14e-18	87.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4E1AK@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	catI	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158249_k127_4764422_0	469378.Ccur_12740	1.037e-50	187.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CV13@84998|Coriobacteriia	84998|Coriobacteriia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158249_k127_4764422_1	641491.DND132_0153	1.776e-17	95.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2M7XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158249_k127_4774459_0	1123023.JIAI01000047_gene9255	1.344e-159	522.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4EA8G@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158249_k127_4774459_2	593750.Metfor_0988	1.169e-47	184.0	COG1226@1|root,arCOG01964@2157|Archaea,2Y19J@28890|Euryarchaeota,2NADN@224756|Methanomicrobia	224756|Methanomicrobia	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158249_k127_4774459_1	269797.Mbar_A2518	2.361e-151	500.0	arCOG02806@1|root,arCOG02806@2157|Archaea,2XVAW@28890|Euryarchaeota,2NA80@224756|Methanomicrobia	224756|Methanomicrobia	P	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
SRR25158249_k127_4774459_3	525904.Tter_1320	1.708e-31	127.0	COG0555@1|root,COG0555@2|Bacteria,2NPSC@2323|unclassified Bacteria	2|Bacteria	O	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158249_k127_4778699_1	404589.Anae109_2130	1.973e-110	372.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158249_k127_4778699_0	1408419.JHYG01000010_gene2462	5.103e-121	422.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JQQC@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158249_k127_4778699_2	1169154.KB897789_gene342	5.573e-83	287.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158249_k127_4778699_3	1464048.JNZS01000051_gene2371	3.467e-73	262.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4D8TN@85008|Micromonosporales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158249_k127_4782502_1	264732.Moth_1943	7.88e-64	226.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,42EUH@68295|Thermoanaerobacterales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158249_k127_4782502_2	1120972.AUMH01000010_gene366	1.11e-43	162.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,279UB@186823|Alicyclobacillaceae	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158249_k127_4782502_0	103733.JNYO01000013_gene4275	1.933e-120	402.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DXZ6@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158249_k127_4782502_3	330084.JNYZ01000013_gene5824	3.357e-18	87.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4E30H@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158249_k127_4792959_0	562970.Btus_2199	1.072e-78	279.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,27838@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
SRR25158249_k127_4792959_2	1120971.AUCA01000021_gene1057	5.1e-21	102.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,278CQ@186823|Alicyclobacillaceae	91061|Bacilli	K	Regulates arginine biosynthesis genes	argR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158249_k127_4792959_1	1342299.Z947_3935	1.057e-25	112.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,3ZVHK@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158249_k127_4812111_0	525904.Tter_0081	2.131e-71	244.0	COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria	2|Bacteria	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158249_k127_4812111_1	1211815.CBYP010000060_gene3122	1.77e-59	215.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4EU19@85013|Frankiales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158249_k127_4812111_3	498761.HM1_0300	5.382e-29	124.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158249_k127_4812111_2	1380390.JIAT01000016_gene5623	1.221e-39	161.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CRTE@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158249_k127_4816666_2	452863.Achl_1114	1.969e-12	79.0	2AFVV@1|root,33H4H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4816666_1	358396.C445_05253	1.809e-23	111.0	arCOG06802@1|root,arCOG06802@2157|Archaea,2XVYT@28890|Euryarchaeota,23TZE@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4816666_0	351607.Acel_0523	2.218e-44	163.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4ESWT@85013|Frankiales	201174|Actinobacteria	S	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRR25158249_k127_4818813_0	1380347.JNII01000007_gene178	4.468e-93	323.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158249_k127_4818813_2	1121272.KB903256_gene5661	6.143e-08	59.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,4DG1X@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4818813_1	335541.Swol_1784	9.557e-63	225.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,42JPM@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158249_k127_4819682_1	1382356.JQMP01000003_gene1959	7.135e-72	261.0	COG0642@1|root,COG2205@2|Bacteria,2GAAW@200795|Chloroflexi,27Z8B@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158249_k127_4819682_2	765911.Thivi_2384	1.122e-29	136.0	COG3187@1|root,COG3187@2|Bacteria,1NGG1@1224|Proteobacteria,1S7JT@1236|Gammaproteobacteria,1WYQQ@135613|Chromatiales	135613|Chromatiales	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
SRR25158249_k127_4819682_0	2002.JOEQ01000001_gene4684	1.55e-143	466.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4EFWX@85012|Streptosporangiales	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	xyoA	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158249_k127_4827313_1	1120950.KB892770_gene1394	1.398e-34	140.0	COG3275@1|root,COG3275@2|Bacteria,2IK2P@201174|Actinobacteria	201174|Actinobacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
SRR25158249_k127_4827313_0	1121272.KB903252_gene1184	1.62e-176	563.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4D931@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158249_k127_4838828_1	649638.Trad_2054	4.156e-80	276.0	COG0438@1|root,COG0438@2|Bacteria,1WJBK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_4838828_2	649638.Trad_2054	1.164e-75	267.0	COG0438@1|root,COG0438@2|Bacteria,1WJBK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_4838828_0	401526.TcarDRAFT_0731	1.137e-132	431.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,4H3TT@909932|Negativicutes	909932|Negativicutes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158249_k127_4838828_3	926569.ANT_27040	1.438e-29	120.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	ycdQ	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
SRR25158249_k127_484201_0	1172179.AUKV01000005_gene5743	1.079e-40	158.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158249_k127_484201_2	1123392.AQWL01000001_gene1481	1.929e-06	56.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2W90N@28216|Betaproteobacteria,1KRZ3@119069|Hydrogenophilales	119069|Hydrogenophilales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
SRR25158249_k127_484201_1	13690.CP98_04528	4.988e-17	89.0	COG0500@1|root,COG0726@1|root,COG1215@1|root,COG0500@2|Bacteria,COG0726@2|Bacteria,COG1215@2|Bacteria,1RIMV@1224|Proteobacteria,2TW81@28211|Alphaproteobacteria,2KECZ@204457|Sphingomonadales	204457|Sphingomonadales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	NodS
SRR25158249_k127_4858660_0	1133850.SHJG_2419	7.455e-140	454.0	COG3299@1|root,COG3299@2|Bacteria,2GM5C@201174|Actinobacteria	201174|Actinobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158249_k127_4858660_2	146922.JOFU01000064_gene40	7.968e-56	202.0	COG3628@1|root,COG3628@2|Bacteria,2IFJ6@201174|Actinobacteria	201174|Actinobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SRR25158249_k127_4858660_1	1209984.BN978_05089	2.833e-112	382.0	COG3501@1|root,COG3501@2|Bacteria,2GP13@201174|Actinobacteria,237XK@1762|Mycobacteriaceae	201174|Actinobacteria	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SRR25158249_k127_4858660_3	1869.MB27_02345	3.867e-37	149.0	COG1652@1|root,COG1652@2|Bacteria,2IAAU@201174|Actinobacteria,4DERJ@85008|Micromonosporales	201174|Actinobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158249_k127_4858660_4	479431.Namu_1904	1.502e-28	120.0	2CCBI@1|root,32RVA@2|Bacteria,2IFX8@201174|Actinobacteria,4EW4C@85013|Frankiales	201174|Actinobacteria	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR25158249_k127_4858660_5	680198.SCAB_27651	1.344e-05	57.0	2DFCX@1|root,2ZRD6@2|Bacteria,2GRS1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4859380_1	1380350.JIAP01000018_gene175	3.837e-74	257.0	COG0006@1|root,COG0006@2|Bacteria,1N8DW@1224|Proteobacteria,2U2SF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158249_k127_4859380_0	1082931.KKY_3572	4.784e-174	563.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria,2U0PC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158249_k127_4859380_2	452637.Oter_0338	4.349e-21	95.0	COG0673@1|root,COG0673@2|Bacteria,46TZD@74201|Verrucomicrobia,3K7GN@414999|Opitutae	2|Bacteria	C	PFAM oxidoreductase domain protein	socC	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158249_k127_4905973_1	1449976.KALB_6351	2.608e-15	75.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158249_k127_4905973_0	379066.GAU_2901	9.512e-25	111.0	COG0125@1|root,COG0125@2|Bacteria,1ZUCV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR25158249_k127_4905973_2	1209984.BN978_03406	7.472e-14	80.0	COG1680@1|root,COG1680@2|Bacteria,2HSHT@201174|Actinobacteria,23C7B@1762|Mycobacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158249_k127_4907584_2	1869.MB27_09315	2.7e-30	126.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4DBBD@85008|Micromonosporales	201174|Actinobacteria	S	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158249_k127_4907584_1	498848.TaqDRAFT_3709	6.585e-31	130.0	COG0316@1|root,COG0316@2|Bacteria,1WKA9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the HesB IscA family	hesB	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158249_k127_4907584_0	562970.Btus_1243	6.029e-164	526.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158249_k127_4923818_0	1394178.AWOO02000016_gene6843	1.265e-66	235.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4EFVN@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158249_k127_4941821_1	1128421.JAGA01000004_gene2593	4.194e-37	144.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158249_k127_4941821_0	1476583.DEIPH_ctg021orf0067	1.442e-85	292.0	COG0183@1|root,COG0183@2|Bacteria,1WID7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158249_k127_4959167_1	234267.Acid_1859	9.06e-14	76.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria	57723|Acidobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158249_k127_4959167_0	273068.TTE2389	3.588e-212	674.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158249_k127_4965760_0	316274.Haur_0301	5.949e-179	581.0	COG4354@1|root,COG4354@2|Bacteria,2G79X@200795|Chloroflexi	200795|Chloroflexi	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
SRR25158249_k127_4965760_2	195250.CM001776_gene772	1.936e-57	213.0	2D20V@1|root,32TBV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
SRR25158249_k127_4965760_1	316274.Haur_4591	5.95e-102	338.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158249_k127_4970441_3	445971.ANASTE_00222	4.975e-83	286.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.46,2.7.8.47	ko:K18704,ko:K21592	-	-	R11613,R11614,R11621	-	ko00000,ko01000	-	-	-	Glyphos_transf
SRR25158249_k127_4970441_1	1385935.N836_04540	1.056e-90	311.0	COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,1H8UU@1150|Oscillatoriales	1117|Cyanobacteria	I	NAD binding domain of 6-phosphogluconate dehydrogenase	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158249_k127_4970441_0	1340493.JNIF01000003_gene2134	1.414e-140	459.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158249_k127_4970441_6	1198114.AciX9_1361	8.897e-26	123.0	COG0590@1|root,COG0590@2|Bacteria,3Y4KB@57723|Acidobacteria,2JJC6@204432|Acidobacteriia	204432|Acidobacteriia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	DUF3175,MafB19-deam
SRR25158249_k127_4970441_5	1449058.JQKT01000007_gene1628	8.882e-48	175.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,4FQ8Z@85023|Microbacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158249_k127_4970441_2	765420.OSCT_0825	2.667e-86	314.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi,37532@32061|Chloroflexia	32061|Chloroflexia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158249_k127_4970441_7	1232410.KI421424_gene1852	1.447e-25	112.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,43SPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158249_k127_4970441_4	1382356.JQMP01000003_gene2082	2.097e-72	250.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158249_k127_4970441_9	1347369.CCAD010000071_gene3617	4.046e-05	47.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes,4IMUS@91061|Bacilli,1ZKVY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4970441_8	1382230.ASAP_2763	2.603e-15	78.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_4977197_1	1352941.M877_07265	1.088e-61	218.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158249_k127_4977197_0	324602.Caur_1078	5.403e-104	358.0	COG1653@1|root,COG1653@2|Bacteria,2G7RQ@200795|Chloroflexi,377M8@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
SRR25158249_k127_4977197_2	926550.CLDAP_13300	7.25e-52	192.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
SRR25158249_k127_4996802_1	1303692.SFUL_1921	9.561e-114	387.0	COG0477@1|root,COG1846@1|root,COG0477@2|Bacteria,COG1846@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_4996802_3	1051501.AYTL01000029_gene1572	2.86e-09	66.0	COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4HYD5@91061|Bacilli,1ZD03@1386|Bacillus	91061|Bacilli	K	transcriptional	yfiV	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158249_k127_4996802_2	1150864.MILUP08_45432	1.42e-74	261.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4D9KK@85008|Micromonosporales	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158249_k127_4996802_0	383372.Rcas_3398	1.416e-184	598.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,375CH@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158249_k127_5002299_0	1051632.TPY_3740	2.37e-33	141.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158249_k127_5012537_1	321332.CYB_1473	2.366e-42	159.0	COG0652@1|root,COG0652@2|Bacteria,1G5BD@1117|Cyanobacteria,1H0AB@1129|Synechococcus	1117|Cyanobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rot	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158249_k127_5012537_0	391037.Sare_0879	3.072e-107	355.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4D8NB@85008|Micromonosporales	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158249_k127_5018902_0	1349820.M707_18920	1.092e-75	266.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,1W7RC@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158249_k127_5018902_1	309801.trd_0069	3.543e-45	169.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi,27YBF@189775|Thermomicrobia	189775|Thermomicrobia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158249_k127_5024535_0	580332.Slit_2416	1.977e-74	259.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
SRR25158249_k127_5024535_1	1175306.GWL_41810	6.14e-56	205.0	COG0583@1|root,COG0583@2|Bacteria,1MV0E@1224|Proteobacteria,2VM44@28216|Betaproteobacteria,475XE@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158249_k127_5057988_0	1121472.AQWN01000007_gene1144	3.322e-67	235.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158249_k127_5057988_1	485913.Krac_8438	2.208e-37	156.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158249_k127_5076149_2	1121382.JQKG01000021_gene1904	1.977e-12	67.0	arCOG06733@1|root,313GU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5076149_0	298655.KI912267_gene7766	1.442e-78	269.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
SRR25158249_k127_5076149_1	351607.Acel_1472	1.812e-28	122.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158249_k127_5081805_7	1226322.HMPREF1545_03701	3.117e-11	63.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158249_k127_5081805_6	1211815.CBYP010000046_gene954	1.308e-17	85.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4ETBC@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158249_k127_5081805_8	160799.PBOR_32935	2.544e-06	52.0	COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,26ZXQ@186822|Paenibacillaceae	91061|Bacilli	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158249_k127_5081805_1	1382306.JNIM01000001_gene88	3.68e-74	257.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158249_k127_5081805_2	309801.trd_0681	1.045e-56	202.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi,27Y72@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158249_k127_5081805_0	264732.Moth_2471	1.43e-90	313.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158249_k127_5081805_5	867903.ThesuDRAFT_00549	7.002e-23	107.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WCJV@538999|Clostridiales incertae sedis	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158249_k127_5081805_4	891968.Anamo_0206	2.438e-38	151.0	COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes	508458|Synergistetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158249_k127_5081805_3	1194165.CAJF01000023_gene3158	2.069e-55	203.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158249_k127_5088723_0	469383.Cwoe_3190	8.33e-121	400.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158249_k127_5088723_3	292459.STH1529	2.799e-18	92.0	COG1595@1|root,COG1595@2|Bacteria,1VFRW@1239|Firmicutes,24U3P@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_5088723_1	370438.PTH_2363	7.494e-63	235.0	COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,24AHG@186801|Clostridia,2659C@186807|Peptococcaceae	186801|Clostridia	S	Acyl-CoA thioester hydrolase/BAAT N-terminal region	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Bile_Hydr_Trans,DLH
SRR25158249_k127_5088723_2	1121123.AUAO01000002_gene479	8.487e-24	108.0	COG1595@1|root,COG1595@2|Bacteria,1PBHM@1224|Proteobacteria,2UB0K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_5088723_4	1382306.JNIM01000001_gene1121	7.494e-07	62.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G7SH@200795|Chloroflexi	200795|Chloroflexi	EU	SPTR D1C8R1 Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158249_k127_5092031_0	1121013.P873_13165	2.779e-180	575.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1X3P1@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
SRR25158249_k127_5092031_3	1298863.AUEP01000005_gene2687	1.455e-17	93.0	2C4JJ@1|root,32RE3@2|Bacteria,2IKF1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158249_k127_5092031_2	679926.Mpet_0265	7.348e-37	152.0	COG1226@1|root,arCOG01964@2157|Archaea,2Y19J@28890|Euryarchaeota,2NADN@224756|Methanomicrobia	224756|Methanomicrobia	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158249_k127_5092031_1	1283287.KB822579_gene2187	2.105e-37	149.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4DNSA@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158249_k127_5098427_1	1125863.JAFN01000001_gene765	8.305e-83	291.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158249_k127_5098427_0	562970.Btus_1451	6.945e-146	475.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,2785M@186823|Alicyclobacillaceae	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158249_k127_5115335_0	1128421.JAGA01000002_gene1840	1.669e-74	266.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22,MFS_1
SRR25158249_k127_5115335_2	1126627.BAWE01000004_gene4445	1.853e-11	78.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2U1BI@28211|Alphaproteobacteria,3JVY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
SRR25158249_k127_5115335_4	1250006.JHZZ01000001_gene144	1.162e-06	62.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4NJCR@976|Bacteroidetes,1HZA7@117743|Flavobacteriia,3VW2A@52959|Polaribacter	976|Bacteroidetes	M	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SdrD_B
SRR25158249_k127_5115335_3	1304875.JAFZ01000001_gene1599	9.629e-07	57.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158249_k127_5115335_1	1121861.KB899910_gene746	1.255e-26	110.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2JP95@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158249_k127_5128743_0	1128421.JAGA01000003_gene2953	3.271e-74	267.0	COG0366@1|root,COG0366@2|Bacteria,2NQQN@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158249_k127_5128743_1	452637.Oter_4531	8.522e-15	78.0	COG4805@1|root,COG4805@2|Bacteria,46T5D@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158249_k127_51307_0	2342.SOPEG_3264	7.072e-60	217.0	COG0546@1|root,COG0546@2|Bacteria,1QUR1@1224|Proteobacteria	1224|Proteobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	Hydrolase
SRR25158249_k127_51307_1	867845.KI911784_gene2853	3.647e-31	138.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
SRR25158249_k127_5156833_4	1236959.BAMT01000002_gene2128	6.735e-22	97.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,2KKDP@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158249_k127_5156833_1	867903.ThesuDRAFT_00685	6.078e-59	220.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158249_k127_5156833_5	1206725.BAFU01000044_gene2047	6.489e-08	65.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4FVIV@85025|Nocardiaceae	201174|Actinobacteria	M	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158249_k127_5156833_3	1392502.JNIO01000008_gene2910	6.671e-27	113.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,4H4TQ@909932|Negativicutes	909932|Negativicutes	S	Protein of unknown function (DUF1290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158249_k127_5156833_0	1382306.JNIM01000001_gene41	2.161e-126	416.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158249_k127_5156833_2	1463920.JOGB01000016_gene5501	7.634e-35	136.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158249_k127_5159326_3	1048339.KB913029_gene3545	2.599e-58	207.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4ES21@85013|Frankiales	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158249_k127_5159326_0	1394178.AWOO02000028_gene5316	3.221e-130	429.0	COG0687@1|root,COG0687@2|Bacteria,2I10F@201174|Actinobacteria,4EJAK@85012|Streptosporangiales	2|Bacteria	E	Bacterial extracellular solute-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRR25158249_k127_5159326_1	1380390.JIAT01000011_gene2576	1.741e-96	329.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4CSJC@84995|Rubrobacteria	84995|Rubrobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158249_k127_5159326_2	1380390.JIAT01000011_gene2575	1.231e-91	309.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4CQ2P@84995|Rubrobacteria	201174|Actinobacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158249_k127_5159326_5	1380347.JNII01000005_gene3708	2.747e-14	78.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4ET38@85013|Frankiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158249_k127_5159326_4	446462.Amir_0405	4.199e-38	152.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158249_k127_5162256_4	370438.PTH_1859	7.895e-15	85.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,261EW@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158249_k127_5162256_3	1121472.AQWN01000005_gene2392	6.394e-54	205.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,260TT@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158249_k127_5162256_1	138119.DSY2908	1.425e-78	288.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158249_k127_5162256_2	1121468.AUBR01000006_gene362	5.151e-68	251.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158249_k127_5162256_0	1382356.JQMP01000004_gene471	2.968e-80	276.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158249_k127_5169242_2	485913.Krac_8940	1.522e-06	55.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRR25158249_k127_5169242_0	1382356.JQMP01000003_gene1892	2.37e-89	310.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_5169242_1	1122915.AUGY01000013_gene2877	1.139e-33	149.0	COG4346@1|root,COG5650@1|root,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4ISHD@91061|Bacilli,26SCF@186822|Paenibacillaceae	91061|Bacilli	O	Glycosyl transferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	F5_F8_type_C,GT87,PMT,PMT_2,PMT_4TMC
SRR25158249_k127_517041_0	1120949.KB903296_gene9351	2.214e-129	437.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DH81@85008|Micromonosporales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,PA,Peptidase_S8,SLH,fn3_5
SRR25158249_k127_5180474_0	1828.JOKB01000013_gene3866	1.146e-127	418.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4G5PW@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158249_k127_5180474_2	383372.Rcas_3558	6.858e-42	169.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,375ST@32061|Chloroflexia	32061|Chloroflexia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158249_k127_5180474_1	1136417.AZWE01000041_gene180	2.814e-42	170.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4DBZV@85008|Micromonosporales	201174|Actinobacteria	P	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158249_k127_5189610_2	1246459.KB898353_gene347	4.392e-63	235.0	COG1345@1|root,COG2931@1|root,COG2982@1|root,COG3209@1|root,COG3210@1|root,COG5295@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BB16@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,DUF4347,HCBP_related,He_PIG,HemolysinCabind,Metallophos,P_proprotein,Peptidase_S8
SRR25158249_k127_5189610_0	697281.Mahau_2191	3.666e-248	800.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F44@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158249_k127_5189610_1	697281.Mahau_2190	2.453e-225	720.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,42FRT@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158249_k127_5189610_4	1122939.ATUD01000011_gene2179	7.13e-10	68.0	COG1846@1|root,COG1846@2|Bacteria,2IHYF@201174|Actinobacteria,4CQVQ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158249_k127_5189610_3	68170.KL590533_gene5261	9.832e-42	158.0	COG0842@1|root,COG0842@2|Bacteria,2I0HP@201174|Actinobacteria,4E1P2@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158249_k127_5203224_3	290397.Adeh_3387	2.64e-07	60.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2YVHS@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158249_k127_5203224_0	661478.OP10G_0129	2.89e-135	439.0	COG0005@1|root,COG0005@2|Bacteria	2|Bacteria	F	purine-nucleoside phosphorylase activity	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158249_k127_5203224_2	1382356.JQMP01000001_gene793	1.146e-15	85.0	COG3576@1|root,COG3576@2|Bacteria,2GA9W@200795|Chloroflexi,27YJR@189775|Thermomicrobia	189775|Thermomicrobia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158249_k127_5203224_1	1120950.KB892763_gene5533	2.258e-54	198.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DQPN@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_5215706_1	67315.JOBD01000046_gene818	9.906e-20	93.0	COG2197@1|root,COG2197@2|Bacteria,2GN8F@201174|Actinobacteria	201174|Actinobacteria	K	bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158249_k127_5215706_0	1122611.KB904032_gene5423	1.011e-161	520.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4EPW9@85012|Streptosporangiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
SRR25158249_k127_5224268_1	404380.Gbem_0872	6.196e-15	76.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,43U8A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158249_k127_5224268_0	1449126.JQKL01000003_gene1735	2.063e-92	323.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,26805@186813|unclassified Clostridiales	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158249_k127_5226142_0	591001.Acfer_1350	3.835e-120	392.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4H32E@909932|Negativicutes	909932|Negativicutes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158249_k127_5226142_1	497964.CfE428DRAFT_4032	1.168e-06	59.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yprA	-	3.4.11.19	ko:K01266,ko:K07052	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abi
SRR25158249_k127_5230172_1	1121106.JQKB01000022_gene3702	3.63e-54	203.0	COG0402@1|root,COG0402@2|Bacteria,1MVMR@1224|Proteobacteria,2U0AM@28211|Alphaproteobacteria,2JRJS@204441|Rhodospirillales	204441|Rhodospirillales	F	Amidohydrolase family	-	-	3.5.2.18	ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158249_k127_5230172_0	1297570.MESS4_360163	9.591e-61	222.0	28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,2TTW0@28211|Alphaproteobacteria,43MWI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Amino acid synthesis	MA20_26545	-	-	-	-	-	-	-	-	-	-	-	AA_synth
SRR25158249_k127_5230172_2	675635.Psed_6676	1.719e-15	81.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DXS2@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_5234_7	76636.JOEC01000001_gene252	8.916e-17	95.0	COG0454@1|root,COG0456@2|Bacteria,2I9GA@201174|Actinobacteria,4FN8E@85023|Microbacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_5234_1	1297865.APJD01000003_gene6065	4.06e-99	335.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2TR5R@28211|Alphaproteobacteria,3K3ZY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	RsgA GTPase	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158249_k127_5234_3	1128421.JAGA01000003_gene3553	3.159e-83	284.0	COG0842@1|root,COG0842@2|Bacteria,2NQR6@2323|unclassified Bacteria	2|Bacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158249_k127_5234_2	1128421.JAGA01000003_gene3545	1.147e-90	311.0	COG1131@1|root,COG1131@2|Bacteria,2NQB3@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_5234_8	1121946.AUAX01000036_gene1923	9.372e-06	58.0	2DPD0@1|root,331J4@2|Bacteria,2IFZU@201174|Actinobacteria,4DCU1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5234_6	1121924.ATWH01000002_gene3696	9.511e-36	143.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria,4FNS3@85023|Microbacteriaceae	201174|Actinobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158249_k127_5234_4	1713.JOFV01000018_gene170	2.809e-42	162.0	2E4HJ@1|root,32ZCP@2|Bacteria,2IIYC@201174|Actinobacteria,4F2Y6@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5234_5	1336243.JAEA01000001_gene1662	1.919e-36	142.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2U9DU@28211|Alphaproteobacteria,1JVSX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158249_k127_5234_0	1382356.JQMP01000001_gene835	4.243e-108	355.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRR25158249_k127_5266023_0	867903.ThesuDRAFT_00843	4.677e-21	99.0	COG1276@1|root,COG2010@1|root,COG1276@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	copC	-	-	ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	AhpC-TSA,CopC,CopD,Cytochrome_CBB3
SRR25158249_k127_5266023_1	626418.bglu_2g14940	3.275e-07	61.0	COG2372@1|root,COG2372@2|Bacteria,1N8SS@1224|Proteobacteria,2VXMG@28216|Betaproteobacteria,1K8IC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Copper resistance protein	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
SRR25158249_k127_5294293_0	1123320.KB889713_gene8085	4.266e-46	171.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158249_k127_5294293_3	926550.CLDAP_32530	7.363e-25	110.0	COG3576@1|root,COG3576@2|Bacteria,2GA9W@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158249_k127_5294293_2	926550.CLDAP_32530	3.903e-26	115.0	COG3576@1|root,COG3576@2|Bacteria,2GA9W@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158249_k127_5294293_1	1298863.AUEP01000001_gene1008	4.537e-42	166.0	COG3420@1|root,COG3420@2|Bacteria,2GXS5@201174|Actinobacteria	201174|Actinobacteria	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5335264_4	309801.trd_0102	3.354e-32	138.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,27XZ8@189775|Thermomicrobia	189775|Thermomicrobia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158249_k127_5335264_3	179408.Osc7112_2123	1.056e-41	169.0	COG2931@1|root,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria,1H8AY@1150|Oscillatoriales	1117|Cyanobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF11,DUF4347,FG-GAP,He_PIG,HemolysinCabind,VCBS
SRR25158249_k127_5335264_0	309799.DICTH_1642	1.207e-73	272.0	COG1609@1|root,COG2199@1|root,COG2203@1|root,COG2206@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG_3	-	-	ko:K02103,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Peripla_BP_3
SRR25158249_k127_5335264_5	35754.JNYJ01000009_gene1932	5.22e-24	108.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4DJEC@85008|Micromonosporales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158249_k127_5335264_7	1121272.KB903261_gene6196	4.618e-10	73.0	COG0726@1|root,COG3386@1|root,COG0726@2|Bacteria,COG3386@2|Bacteria,2GNF1@201174|Actinobacteria,4DBWD@85008|Micromonosporales	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5335264_2	1123057.P872_21170	4.134e-42	161.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	tauX	-	-	ko:K07255,ko:K21700	ko00430,map00430	-	R01685	RC00062	ko00000,ko00001,ko01000	-	-	-	SnoaL_2
SRR25158249_k127_5335264_1	512565.AMIS_43030	2.545e-50	183.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4DE4P@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158249_k127_5335264_6	484770.UFO1_1182	3.37e-16	83.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_5361073_0	1380354.JIAN01000008_gene3518	6.924e-123	401.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria	201174|Actinobacteria	P	Iron permease FTR1	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1,Peptidase_M75
SRR25158249_k127_5361073_1	593907.Celgi_2504	3.394e-117	383.0	COG2822@1|root,COG2822@2|Bacteria,2GJPY@201174|Actinobacteria	201174|Actinobacteria	P	periplasmic lipoprotein involved in iron transport	efeO	-	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Cupredoxin_1,Peptidase_M75
SRR25158249_k127_5384993_0	479434.Sthe_1273	8.658e-124	412.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158249_k127_5384993_1	383372.Rcas_4069	5.21e-84	295.0	COG0793@1|root,COG0793@2|Bacteria,2G6A8@200795|Chloroflexi,376NS@32061|Chloroflexia	32061|Chloroflexia	M	PFAM PDZ DHR GLGF domain protein	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158249_k127_5384993_2	871963.Desdi_0917	4.887e-27	117.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,262HD@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158249_k127_5384993_3	331113.SNE_A18580	1.419e-18	88.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
SRR25158249_k127_5391732_0	1394178.AWOO02000034_gene8339	6.95e-86	317.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4EG63@85012|Streptosporangiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,TPR_12
SRR25158249_k127_5391732_1	469383.Cwoe_5333	1.403e-21	97.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4CRCB@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_5407398_2	1382356.JQMP01000004_gene418	3.284e-19	91.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158249_k127_5407398_1	765420.OSCT_1025	2.149e-35	149.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,3772Y@32061|Chloroflexia	32061|Chloroflexia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158249_k127_5407398_0	330214.NIDE3962	3.344e-51	191.0	COG0705@1|root,COG0705@2|Bacteria,3J16E@40117|Nitrospirae	40117|Nitrospirae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158249_k127_5408624_2	314225.ELI_09190	3.384e-10	66.0	COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2UFVP@28211|Alphaproteobacteria,2K4QR@204457|Sphingomonadales	204457|Sphingomonadales	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
SRR25158249_k127_5408624_3	68570.DC74_5157	2.83e-05	51.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158249_k127_5408624_1	710686.Mycsm_05883	7.071e-11	74.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,2329A@1762|Mycobacteriaceae	201174|Actinobacteria	P	Arsenical pump membrane protein	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
SRR25158249_k127_5408624_0	1380347.JNII01000005_gene3108	3.266e-38	149.0	COG1917@1|root,COG2114@1|root,COG1917@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158249_k127_5417378_2	1463920.JOGB01000001_gene3481	2.939e-28	115.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_5417378_1	284031.JNXD01000030_gene2640	4.934e-172	546.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria	201174|Actinobacteria	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158249_k127_5417378_3	644548.SCNU_01830	5.232e-28	124.0	2BF47@1|root,328WE@2|Bacteria,2IM74@201174|Actinobacteria,4GEAZ@85026|Gordoniaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
SRR25158249_k127_5417378_0	1385518.N798_12185	1.934e-262	820.0	COG0296@1|root,COG0296@2|Bacteria,2IA2H@201174|Actinobacteria,4FEKD@85021|Intrasporangiaceae	201174|Actinobacteria	G	1,4-alpha-glucan branching enzyme	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158249_k127_5417981_1	411467.BACCAP_02332	2.353e-45	175.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,267NT@186813|unclassified Clostridiales	186801|Clostridia	J	Psort location Cytoplasmic, score	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158249_k127_5417981_0	316274.Haur_4220	1.445e-62	223.0	COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia	32061|Chloroflexia	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158249_k127_5417981_2	1173264.KI913949_gene1308	2.828e-34	143.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158249_k127_5417981_3	1192034.CAP_8545	1.539e-30	132.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria,43AS2@68525|delta/epsilon subdivisions,2X666@28221|Deltaproteobacteria,2Z27D@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158249_k127_5422261_1	1128427.KB904821_gene767	0.0007487	45.0	COG1950@1|root,COG1950@2|Bacteria,1G6Q0@1117|Cyanobacteria,1HBU1@1150|Oscillatoriales	1117|Cyanobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158249_k127_5422261_0	1385517.N800_06160	8.84e-92	321.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158249_k127_5430242_16	1033802.SSPSH_002618	1.462e-07	62.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158249_k127_5430242_15	649638.Trad_0737	4.324e-11	75.0	COG3307@1|root,COG3307@2|Bacteria,1WNB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158249_k127_5430242_6	926550.CLDAP_36300	1.574e-75	288.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi	200795|Chloroflexi	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5430242_4	316274.Haur_4278	8.702e-82	282.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158249_k127_5430242_11	1254432.SCE1572_33010	6.489e-40	162.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2YY5H@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_5430242_9	1090318.ATTI01000001_gene329	2.525e-49	190.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K23Q@204457|Sphingomonadales	204457|Sphingomonadales	M	NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158249_k127_5430242_13	1370125.AUWT01000029_gene548	4.207e-27	127.0	COG0673@1|root,COG0673@2|Bacteria,2HFC4@201174|Actinobacteria,23BIK@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158249_k127_5430242_8	1121920.AUAU01000019_gene2560	1.276e-52	193.0	COG2148@1|root,COG2148@2|Bacteria,3Y4VZ@57723|Acidobacteria	57723|Acidobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158249_k127_5430242_2	156889.Mmc1_2166	1.929e-94	321.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158249_k127_5430242_1	880073.Calab_2793	4.911e-121	400.0	COG0399@1|root,COG0399@2|Bacteria,2NNND@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158249_k127_5430242_14	1250278.JQNQ01000001_gene1100	1.072e-18	98.0	COG1216@1|root,COG1216@2|Bacteria,4NI78@976|Bacteroidetes,1HXTP@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158249_k127_5430242_5	266940.Krad_3896	2.718e-79	290.0	COG1132@1|root,COG1132@2|Bacteria,2HXAQ@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158249_k127_5430242_7	243231.GSU1973	1.205e-69	243.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,42RVS@68525|delta/epsilon subdivisions,2WQYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158249_k127_5430242_10	1268237.G114_10585	3.672e-41	174.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,1Y5S9@135624|Aeromonadales	135624|Aeromonadales	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SRR25158249_k127_5430242_0	243231.GSU1970	5.489e-149	494.0	COG2089@1|root,COG2089@2|Bacteria,1N3PZ@1224|Proteobacteria,43A02@68525|delta/epsilon subdivisions,2X267@28221|Deltaproteobacteria,43V56@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NeuB family	neuB	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
SRR25158249_k127_5430242_12	243231.GSU1969	1.084e-39	149.0	28II9@1|root,2Z8JC@2|Bacteria,1NSFW@1224|Proteobacteria,42PTJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_5435465_2	1078085.HMPREF1210_03455	1.088e-34	153.0	2DBV7@1|root,2ZB9P@2|Bacteria,1UBN2@1239|Firmicutes,4HEYF@91061|Bacilli,26GJQ@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158249_k127_5435465_0	40571.JOEA01000010_gene2860	1.232e-85	287.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4E1BA@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158249_k127_5435465_1	35754.JNYJ01000001_gene7151	5.375e-49	181.0	COG3832@1|root,COG3832@2|Bacteria,2HQ66@201174|Actinobacteria,4DFVF@85008|Micromonosporales	201174|Actinobacteria	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158249_k127_544614_1	1123251.ATWM01000004_gene1974	1.855e-40	154.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FE6A@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
SRR25158249_k127_544614_2	926550.CLDAP_23770	1.829e-30	136.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158249_k127_544614_0	525904.Tter_2280	4.991e-73	259.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158249_k127_5463723_0	1121272.KB903290_gene4608	1.133e-124	403.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4D8NI@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158249_k127_5469664_0	1197706.AKKK01000001_gene1794	2.615e-84	293.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria	201174|Actinobacteria	E	Alanine racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158249_k127_5469664_1	1380390.JIAT01000013_gene6	8.223e-62	237.0	COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4CTKV@84995|Rubrobacteria	84995|Rubrobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158249_k127_5479102_0	521045.Kole_0242	7.174e-181	586.0	COG0058@1|root,COG0058@2|Bacteria,2GCCY@200918|Thermotogae	200918|Thermotogae	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158249_k127_5479102_1	278963.ATWD01000002_gene693	5.88e-27	119.0	COG0297@1|root,COG0297@2|Bacteria,3Y3IH@57723|Acidobacteria,2JHNU@204432|Acidobacteriia	204432|Acidobacteriia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158249_k127_5479379_1	1123354.AUDR01000014_gene947	5.768e-10	67.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,1KRR5@119069|Hydrogenophilales	119069|Hydrogenophilales	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158249_k127_5479379_0	1267535.KB906767_gene844	1.443e-91	321.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria,2JHUM@204432|Acidobacteriia	204432|Acidobacteriia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158249_k127_5486415_0	479434.Sthe_3265	1.694e-43	179.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi,27XHU@189775|Thermomicrobia	189775|Thermomicrobia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158249_k127_5486415_1	290397.Adeh_1232	1.752e-21	99.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158249_k127_5494551_2	509635.N824_13785	6.381e-87	295.0	COG1830@1|root,COG1830@2|Bacteria,4P0GF@976|Bacteroidetes	976|Bacteroidetes	G	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158249_k127_5494551_0	1081644.IMCC13023_04150	1.678e-117	398.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158249_k127_5494551_3	1160718.SU9_29181	5.918e-85	298.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158249_k127_5494551_4	1122939.ATUD01000002_gene1478	1.057e-71	259.0	COG1070@1|root,COG1070@2|Bacteria,2IE7F@201174|Actinobacteria	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158249_k127_5494551_1	134676.ACPL_3867	2.331e-87	297.0	COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4DGZX@85008|Micromonosporales	201174|Actinobacteria	G	2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
SRR25158249_k127_5502588_0	479432.Sros_9352	7.485e-82	280.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4EGKS@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,DUF2808,SBP_bac_3
SRR25158249_k127_5502588_1	1894.JOER01000008_gene701	2.29e-78	273.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria	201174|Actinobacteria	ET	ABC transporter substrate-binding protein	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
SRR25158249_k127_5502588_2	1394178.AWOO02000025_gene5013	2.67e-67	240.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4EFY5@85012|Streptosporangiales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158249_k127_5553777_1	525904.Tter_0032	2.609e-76	265.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158249_k127_5553777_0	357808.RoseRS_3857	4.989e-101	343.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	32061|Chloroflexia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158249_k127_600506_0	1121428.DESHY_50042___1	2.827e-125	422.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158249_k127_600506_1	1463920.JOGB01000016_gene5501	2.336e-51	185.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158249_k127_608694_5	446462.Amir_2198	5.986e-21	93.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4DXYE@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158249_k127_608694_3	909613.UO65_3257	6.82e-39	156.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4DYVY@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM cytochrome c oxidase subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158249_k127_608694_8	1449347.JQLN01000004_gene7164	5.439e-06	58.0	COG3794@1|root,COG3794@2|Bacteria,2GS7W@201174|Actinobacteria	201174|Actinobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158249_k127_608694_4	926554.KI912660_gene2385	4.487e-31	128.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158249_k127_608694_0	309801.trd_1149	2.639e-84	297.0	COG1131@1|root,COG1131@2|Bacteria,2G7SA@200795|Chloroflexi,27XY4@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_608694_2	106370.Francci3_1654	4.512e-54	205.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158249_k127_608694_1	526225.Gobs_3384	1.402e-80	275.0	COG0235@1|root,COG0235@2|Bacteria,2HGGU@201174|Actinobacteria,4EWNJ@85013|Frankiales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158249_k127_608694_7	1385518.N798_01320	2.955e-09	68.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,4FEJ3@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR25158249_k127_608694_6	869210.Marky_0019	4.133e-20	102.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1WJBI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
SRR25158249_k127_612775_0	671143.DAMO_2896	9.407e-182	591.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158249_k127_614125_0	357808.RoseRS_2549	1.273e-91	318.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158249_k127_614125_1	246197.MXAN_1407	3.597e-58	206.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,42Q5H@68525|delta/epsilon subdivisions,2WKW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158249_k127_621046_0	1128421.JAGA01000002_gene1692	5.021e-100	331.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158249_k127_621046_1	1128421.JAGA01000002_gene1691	2.807e-92	313.0	COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158249_k127_621046_3	1278073.MYSTI_02482	2.808e-06	57.0	COG1595@1|root,COG1595@2|Bacteria,1R44W@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158249_k127_621046_2	479432.Sros_8401	9.134e-10	71.0	COG3147@1|root,COG3147@2|Bacteria,2ID4R@201174|Actinobacteria,4EHHH@85012|Streptosporangiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_622625_1	1170562.Cal6303_1069	2.364e-72	256.0	COG0474@1|root,COG0474@2|Bacteria,1G3BZ@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158249_k127_622625_2	1089545.KB913037_gene6541	4.809e-22	109.0	COG0346@1|root,COG0346@2|Bacteria,2IQJB@201174|Actinobacteria,4E611@85010|Pseudonocardiales	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158249_k127_622625_0	479434.Sthe_1235	2.795e-146	473.0	COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi,27XJE@189775|Thermomicrobia	189775|Thermomicrobia	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158249_k127_624464_0	479434.Sthe_2483	2.056e-70	250.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi,27XNY@189775|Thermomicrobia	189775|Thermomicrobia	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158249_k127_624464_1	1128421.JAGA01000002_gene426	7.484e-18	96.0	COG1917@1|root,COG1917@2|Bacteria,2NRCD@2323|unclassified Bacteria	2|Bacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158249_k127_629962_1	1382306.JNIM01000001_gene1633	2.516e-38	151.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158249_k127_629962_2	1459636.NTE_00536	3.655e-25	111.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158249_k127_629962_0	543632.JOJL01000020_gene558	2.576e-42	178.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158249_k127_629962_3	886293.Sinac_7034	5.343e-23	115.0	COG4625@1|root,COG4625@2|Bacteria,2J0EF@203682|Planctomycetes	2|Bacteria	S	Bacterial Ig-like domain (group 3)	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,Big_3_5,Cadherin-like,Calx-beta,DUF4347,He_PIG,PATR,TIG,fn3
SRR25158249_k127_635139_0	324602.Caur_1844	1.088e-219	701.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158249_k127_635139_4	1122182.KB903836_gene5077	3.683e-05	53.0	2E9SA@1|root,333YF@2|Bacteria,2GS00@201174|Actinobacteria,4DKQJ@85008|Micromonosporales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_635139_2	1031288.AXAA01000045_gene2167	5.63e-29	125.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,36KFX@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158249_k127_635139_3	1123024.AUII01000052_gene3908	9.071e-18	86.0	COG0640@1|root,COG0640@2|Bacteria,2IKPW@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158249_k127_635139_1	760568.Desku_0156	5.501e-65	235.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,2615A@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
SRR25158249_k127_637739_1	1380390.JIAT01000009_gene904	7.468e-56	222.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria,4CSEW@84995|Rubrobacteria	84995|Rubrobacteria	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158249_k127_637739_0	1254432.SCE1572_13050	5.6e-150	488.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158249_k127_660844_1	1395587.P364_0129145	4.186e-52	194.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158249_k127_660844_3	525904.Tter_0247	1.855e-18	101.0	COG3794@1|root,COG3794@2|Bacteria,2NRPQ@2323|unclassified Bacteria	2|Bacteria	C	blue (type 1) copper	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
SRR25158249_k127_660844_4	1041522.MCOL_V226532	0.0004367	49.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria,239AT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158249_k127_660844_2	1114959.SZMC14600_18404	3.184e-42	165.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4DYE1@85010|Pseudonocardiales	201174|Actinobacteria	P	Zn-dependent hydrolase, glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158249_k127_667900_2	1122223.KB890697_gene1033	7.311e-07	57.0	COG2720@1|root,COG2720@2|Bacteria,1WM1R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158249_k127_667900_1	1416759.AYMR01000007_gene650	1.785e-22	109.0	COG1361@1|root,COG5184@1|root,COG1361@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF11,He_PIG,P_proprotein,Peptidase_S8,SdrD_B
SRR25158249_k127_667900_0	670307.HYPDE_26888	1.394e-27	124.0	COG3210@1|root,COG5295@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,COG5492@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,FG-GAP_2,Glug,Haemagg_act
SRR25158249_k127_688_1	1157635.KB892004_gene4599	7.374e-26	117.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158249_k127_688_0	479434.Sthe_0989	7.948e-47	181.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	189775|Thermomicrobia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158249_k127_694276_0	498761.HM1_3029	1.095e-147	489.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158249_k127_703576_0	525904.Tter_1355	5.404e-75	278.0	COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria	2|Bacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158249_k127_707282_4	649349.Lbys_3228	1.181e-10	75.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,47KWS@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158249_k127_707282_1	1449063.JMLS01000022_gene6439	4.09e-79	284.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,4HC8R@91061|Bacilli,26T6C@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158249_k127_707282_0	562970.Btus_3228	1.378e-101	353.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4HA4Y@91061|Bacilli,278U3@186823|Alicyclobacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158249_k127_707282_3	357808.RoseRS_3676	5.939e-24	112.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi,375IZ@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158249_k127_707282_2	1123511.KB905842_gene1663	9.045e-34	132.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4H438@909932|Negativicutes	909932|Negativicutes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158249_k127_707770_0	1120949.KB903357_gene4802	2.343e-100	349.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4D8Q0@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_719734_1	479434.Sthe_0796	1.885e-27	121.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158249_k127_719734_0	479434.Sthe_1621	0.0	1281.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
SRR25158249_k127_719734_3	926550.CLDAP_25850	6.484e-15	80.0	2ERYI@1|root,33JHP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_719734_2	1410670.JHXF01000019_gene56	4.138e-22	102.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,3WKUR@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158249_k127_720037_6	543632.JOJL01000027_gene2821	3.938e-29	124.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4D9RD@85008|Micromonosporales	201174|Actinobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158249_k127_720037_4	1382356.JQMP01000003_gene1686	2.179e-111	380.0	COG0395@1|root,COG0395@2|Bacteria,2G8BX@200795|Chloroflexi,27Z7I@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
SRR25158249_k127_720037_1	1382356.JQMP01000003_gene1685	3.197e-126	412.0	COG1175@1|root,COG1175@2|Bacteria,2G6P7@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10118,ko:K17316	ko02010,map02010	M00196,M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	BPD_transp_1
SRR25158249_k127_720037_0	1382356.JQMP01000003_gene1684	8.141e-159	514.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158249_k127_720037_5	219305.MCAG_01950	1.331e-95	321.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4D96U@85008|Micromonosporales	201174|Actinobacteria	K	DeoR C terminal sensor domain	glpR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158249_k127_720037_2	661478.OP10G_1601	4.631e-124	413.0	COG1085@1|root,COG1085@2|Bacteria	2|Bacteria	C	galactose-1-phosphate uridylyltransferase	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
SRR25158249_k127_720037_3	876269.ARWA01000001_gene538	8.403e-122	401.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,3NAMK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158249_k127_722122_2	309801.trd_0264	1.377e-61	219.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	189775|Thermomicrobia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158249_k127_722122_0	561175.KB894095_gene2595	1.691e-120	399.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4EIC0@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158249_k127_722122_1	43354.JOIJ01000007_gene1492	5.049e-92	312.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4DZST@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
SRR25158249_k127_766256_2	589865.DaAHT2_2275	1.771e-05	57.0	2F3VZ@1|root,33WN6@2|Bacteria,1NWQ8@1224|Proteobacteria,42ZX2@68525|delta/epsilon subdivisions,2WV88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_766256_1	1089551.KE386572_gene1955	1.574e-52	206.0	COG3119@1|root,COG3119@2|Bacteria,1MYHH@1224|Proteobacteria,2UA67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158249_k127_766256_0	861299.J421_6055	9.617e-146	476.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	2.1.1.242,2.1.1.303,2.1.1.319	ko:K11434,ko:K15984,ko:K20421	ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922	M00830	R10963,R11216,R11217,R11219	RC00003,RC00392,RC02120,RC03388,RC03390	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	-	-	-	DOT1,Methyltransf_21,Methyltransf_25
SRR25158249_k127_769252_1	1380393.JHVP01000015_gene4188	3.448e-151	484.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria,4ETTI@85013|Frankiales	201174|Actinobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	rhaD	-	1.1.1.1,1.1.1.140,4.1.2.19	ko:K00001,ko:K00068,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R05607,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short,adh_short_C2
SRR25158249_k127_769252_0	67356.KL575637_gene5356	5.072e-205	645.0	COG4952@1|root,COG4952@2|Bacteria,2GK1Z@201174|Actinobacteria	201174|Actinobacteria	M	Isomerase	rhaI	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,RhaA
SRR25158249_k127_769252_3	926550.CLDAP_34840	1.428e-52	196.0	COG1349@1|root,COG1349@2|Bacteria,2G8SX@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158249_k127_769252_2	1121946.AUAX01000011_gene4121	2.952e-82	294.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4DAQF@85008|Micromonosporales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	rbsA	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
SRR25158249_k127_792432_0	885272.JonanDRAFT_0108	1.409e-88	300.0	COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158249_k127_792432_1	469383.Cwoe_5333	3.769e-60	226.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4CRCB@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_805635_0	471223.GWCH70_3007	2.923e-81	278.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,1WF5G@129337|Geobacillus	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158249_k127_805635_2	479434.Sthe_1433	2.508e-39	161.0	COG1434@1|root,COG1434@2|Bacteria,2G996@200795|Chloroflexi,27YFA@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158249_k127_805635_1	1125973.JNLC01000013_gene4048	3.147e-41	163.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,3JU9H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158249_k127_813836_3	1463917.JODC01000007_gene7462	1.167e-45	175.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158249_k127_813836_2	330084.JNYZ01000005_gene1195	1.023e-59	231.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158249_k127_813836_1	351607.Acel_1049	1.207e-94	322.0	COG1172@1|root,COG1172@2|Bacteria,2IAFE@201174|Actinobacteria,4EX5P@85013|Frankiales	201174|Actinobacteria	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158249_k127_813836_0	351607.Acel_1050	2.169e-150	494.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4ESBS@85013|Frankiales	201174|Actinobacteria	P	PFAM ABC transporter	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158249_k127_813836_4	351607.Acel_1051	5.364e-24	104.0	COG1879@1|root,COG1879@2|Bacteria,2IB5Z@201174|Actinobacteria	201174|Actinobacteria	G	ABC-type sugar transport system periplasmic component-like protein	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158249_k127_815717_0	1382356.JQMP01000001_gene1166	4.26e-99	332.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi,27Y2F@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158249_k127_815717_1	1120950.KB892771_gene1287	4.905e-37	147.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4DPZ7@85009|Propionibacteriales	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRR25158249_k127_815747_0	1128421.JAGA01000002_gene906	1.839e-222	714.0	COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158249_k127_817658_0	1411123.JQNH01000001_gene3595	8.634e-72	255.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2TQQK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158249_k127_822077_2	351607.Acel_0525	5.34e-24	109.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EWZZ@85013|Frankiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158249_k127_822077_4	1380394.JADL01000011_gene3902	5.56e-16	81.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2UF3C@28211|Alphaproteobacteria,2JU9S@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158249_k127_822077_1	710696.Intca_2822	8.729e-47	177.0	COG2210@1|root,COG2210@2|Bacteria,2IGW8@201174|Actinobacteria	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158249_k127_822077_3	565033.GACE_0532	2.073e-20	101.0	COG0425@1|root,arCOG02062@2157|Archaea,2XZUG@28890|Euryarchaeota,246G4@183980|Archaeoglobi	183980|Archaeoglobi	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR25158249_k127_822077_0	1521187.JPIM01000137_gene2066	2.072e-113	377.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158249_k127_829851_0	1385518.N798_12125	4.144e-62	216.0	2AKGE@1|root,30DHP@2|Bacteria,2I885@201174|Actinobacteria,4FH35@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_829851_1	1380390.JIAT01000011_gene2542	3.987e-38	153.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158249_k127_829851_2	1089551.KE386572_gene4403	1.125e-34	137.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,4BPCB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	HMGL-like	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158249_k127_830532_0	944481.JAFP01000001_gene1185	2.67e-12	72.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2M7EG@213113|Desulfurellales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158249_k127_830532_1	1122221.JHVI01000002_gene804	1.212e-07	63.0	COG1295@1|root,COG1295@2|Bacteria,1WIGF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158249_k127_834759_2	1380370.JIBA01000018_gene537	6.958e-13	70.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158249_k127_834759_3	1370120.AUWR01000106_gene1732	1.248e-05	53.0	COG3427@1|root,COG3427@2|Bacteria,2IJF7@201174|Actinobacteria,238SI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158249_k127_834759_1	656024.FsymDg_3445	7.434e-39	154.0	COG1409@1|root,COG2365@1|root,COG1409@2|Bacteria,COG2365@2|Bacteria,2HKQQ@201174|Actinobacteria,4EVHD@85013|Frankiales	201174|Actinobacteria	T	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR25158249_k127_834759_0	309801.trd_1336	1.415e-57	219.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158249_k127_835701_0	1410653.JHVC01000009_gene2838	2.732e-34	137.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,36E2C@31979|Clostridiaceae	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158249_k127_835701_1	1229780.BN381_330096	3.236e-22	105.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,3UWSX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158249_k127_858375_3	710696.Intca_0272	3.901e-43	166.0	COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria,4FJWF@85021|Intrasporangiaceae	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158249_k127_858375_4	292459.STH2963	1.943e-29	124.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia	186801|Clostridia	K	domain protein	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
SRR25158249_k127_858375_0	1192034.CAP_6745	7.012e-85	297.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	-	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
SRR25158249_k127_858375_5	1121382.JQKG01000020_gene1208	3.072e-25	115.0	COG1028@1|root,COG1028@2|Bacteria	1121382.JQKG01000020_gene1208|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_858375_1	66429.JOFL01000006_gene1888	2.006e-59	218.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158249_k127_858375_2	448385.sce8130	1.483e-54	198.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158249_k127_866092_2	292459.STH1026	4.597e-24	105.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158249_k127_866092_0	1463856.JOHY01000013_gene6158	1.839e-63	240.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,TIG
SRR25158249_k127_866092_1	1303692.SFUL_2322	3.631e-26	119.0	COG2203@1|root,COG2203@2|Bacteria,2I97I@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
SRR25158249_k127_866092_3	485913.Krac_8232	9.138e-12	73.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158249_k127_868940_2	926569.ANT_28600	1.049e-88	300.0	COG1653@1|root,COG1653@2|Bacteria,2G72Y@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1
SRR25158249_k127_868940_0	40571.JOEA01000014_gene1590	1.114e-100	336.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4DZ1C@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
SRR25158249_k127_868940_3	543632.JOJL01000006_gene9698	1.341e-41	166.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D9IN@85008|Micromonosporales	201174|Actinobacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158249_k127_868940_1	1304880.JAGB01000001_gene616	6.554e-99	344.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158249_k127_88122_2	391735.Veis_0544	4.506e-05	51.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,2VMMY@28216|Betaproteobacteria,4AB83@80864|Comamonadaceae	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	frk	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158249_k127_88122_1	292459.STH1622	1.012e-37	162.0	COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,1TQQU@1239|Firmicutes	1239|Firmicutes	L	Exonuclease	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
SRR25158249_k127_88122_0	867903.ThesuDRAFT_00195	5.791e-47	175.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,25EG8@186801|Clostridia,3WDQS@538999|Clostridiales incertae sedis	186801|Clostridia	KL	PFAM Helicase conserved C-terminal domain	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158249_k127_88273_0	1380390.JIAT01000009_gene1628	2.571e-39	167.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158249_k127_886541_1	1134912.AJTV01000049_gene3635	5.986e-10	61.0	2DPU9@1|root,333E7@2|Bacteria,1N6Y7@1224|Proteobacteria,2UHW4@28211|Alphaproteobacteria,3711A@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	ko:K22014	-	-	-	-	ko00000	-	-	-	-
SRR25158249_k127_886541_0	479434.Sthe_3070	4.127e-130	431.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158249_k127_889632_0	1125863.JAFN01000001_gene2048	3.628e-58	213.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm-2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158249_k127_926493_2	525904.Tter_1481	2.284e-20	98.0	COG2265@1|root,COG2265@2|Bacteria,2NRDB@2323|unclassified Bacteria	2|Bacteria	J	Methyltransferase domain	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31
SRR25158249_k127_926493_1	460265.Mnod_1757	7.053e-24	110.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,1JUR5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158249_k127_926493_0	525904.Tter_2236	3.56e-53	197.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158249_k127_932513_2	1246474.ANBE01000026_gene1822	4.025e-10	65.0	COG0596@1|root,COG0596@2|Bacteria,2H5NQ@201174|Actinobacteria	201174|Actinobacteria	Q	Alpha/beta hydrolase family	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Isochorismatase
SRR25158249_k127_932513_0	266117.Rxyl_1027	2.218e-25	110.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158249_k127_932513_1	208439.AJAP_22175	3.016e-15	79.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158249_k127_932658_2	1274524.BSONL12_11766	1.448e-05	49.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZBY4@1386|Bacillus	91061|Bacilli	S	hydrolases of the HAD superfamily	ykrA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
SRR25158249_k127_932658_1	685778.AORL01000021_gene1255	5.55e-36	147.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,2K1JS@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158249_k127_932658_0	1356854.N007_08805	4.767e-144	469.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,2785X@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158249_k127_948393_1	246194.CHY_0732	1.817e-73	257.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42EM7@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRR25158249_k127_948393_0	1382306.JNIM01000001_gene996	5.068e-122	405.0	COG0493@1|root,COG0493@2|Bacteria,2G82F@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Fer2_4,Fer4,Fer4_20,Pyr_redox_2
SRR25158249_k127_992426_7	756067.MicvaDRAFT_3334	7.91e-13	78.0	COG1196@1|root,COG1196@2|Bacteria,1G2AM@1117|Cyanobacteria,1HI0V@1150|Oscillatoriales	1117|Cyanobacteria	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158249_k127_992426_0	404589.Anae109_4038	4.763e-178	564.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,438FV@68525|delta/epsilon subdivisions,2X3QT@28221|Deltaproteobacteria,2YWVJ@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158249_k127_992426_3	42256.RradSPS_0124	1.778e-54	214.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158249_k127_992426_1	1123320.KB889719_gene7343	2.694e-86	296.0	COG1131@1|root,COG1131@2|Bacteria,2GJ0Y@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158249_k127_992426_5	2002.JOEQ01000002_gene4496	1.521e-52	195.0	COG0842@1|root,COG0842@2|Bacteria,2GK5F@201174|Actinobacteria,4ENNB@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158249_k127_992426_4	1157638.KB892208_gene625	2.718e-53	211.0	COG4585@1|root,COG4585@2|Bacteria,2GKRM@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158249_k127_992426_2	485913.Krac_5377	1.671e-75	265.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158249_k127_992426_6	1041139.KB902646_gene3375	6.312e-33	131.0	2EBN3@1|root,335NA@2|Bacteria,1PS1W@1224|Proteobacteria,2V490@28211|Alphaproteobacteria,4BFSU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158249_k127_99371_1	1120950.KB892763_gene5517	5.369e-122	408.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4DSYV@85009|Propionibacteriales	201174|Actinobacteria	J	Elongation factor G, domain IV	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158249_k127_99371_0	477641.MODMU_1794	4.306e-131	436.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158249_k127_99371_2	1157640.AQWO01000005_gene2020	5.373e-98	325.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158249_k127_998617_1	443906.CMM_2242	6.716e-07	54.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4FM24@85023|Microbacteriaceae	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158249_k127_998617_0	42256.RradSPS_2370	1.934e-68	256.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4CTMV@84995|Rubrobacteria	84995|Rubrobacteria	M	Capsule synthesis protein, CapA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158249_k127_998617_2	1122925.KB895387_gene2807	1.691e-06	51.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 2047 queries scanned
## Total time (seconds): 14.770920991897583
## Rate: 138.58 q/s